1. Work-related asthma in adults with severe asthma from the Korean Severe Asthma Registry (KoSAR)
- Author
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Youngsoo Lee, MD, Sun-Kyung Lee, PhD, So-Young Park, MD, PhD, Min-Hye Kim, MD, PhD, Sung-Yoon Kang, MD, PhD, Ga-Young Ban, MD, PhD, Young-Hee Nam, MD, PhD, Joo-Hee Kim, MD, PhD, Chin Kook Rhee, MD, PhD, Woo-Jung Song, MD, PhD, Jae-Woo Kwon, MD, PhD, Taehoon Lee, MD, PhD, So Ri Kim, MD, PhD, Heung-Woo Park, MD, PhD, You Sook Cho, MD, PhD, Young-Il Koh, MD, PhD, Kwang-Ha Yoo, MD, PhD, Byung-Jae Lee, MD, PhD, Ho Joo Yoon, MD, PhD, Hae-Sim Park, MD, PhD, and Sang-Heon Kim, MD, PhD
- Subjects
Work-related asthma ,Severe asthma ,Quality of life ,Depression ,Anxiety ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Background: Exposure to allergens or irritants in the workplace may affect asthma control and the quality of life (QoL) of patients with asthma. Objective: To examine the prevalence and characteristics of work-related asthma (WRA) in adult patients with severe asthma. Methods: We analyzed data from the Korean Severe Asthma Registry (KoSAR), which is a nationwide multicenter observational study on severe asthma in Korea. Severe asthma was defined according to the American Thoracic Society (ATS) and the European Respiratory Society (ERS) guidelines. WRA was identified on the basis of asthma symptom aggravation at the workplace, as indicated by responses to a structured questionnaire. We compared the demographic and clinical characteristics and QoL between adult patients with severe asthma and WRA and those without WRA. Results: Among 364 patients with severe asthma who were employed at the time of enrollment, 65 (17.9%) had WRA. There were no significant differences in age, sex, obesity, or smoking history between the WRA and non-WRA groups. However, individuals with WRA exhibited a higher prevalence of anxiety (7.7% vs 2.4%, P = 0.046) and depression (12.3% vs 3.7%, P = 0.010) than those without. The levels of asthma control, lung function, and frequency of asthma exacerbations were similar between the two groups, but patients with WRA reported lower QoL, as determined by the Quality of Life Questionnaire for Adult Korean Asthmatics (56.6 ± 14.6 vs. 63.5 ± 13.9, P
- Published
- 2024
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