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To enhance the stability and disturbance rejection of wireless charging systems for electric vehicles, we designed a bilateral collaborative control strategy based on BP neural networks, achieving closed-loop constant voltage control for the secondary rectification circuit. Integrating BP neural network adaptive PID parameters with dual-phase-shift control, this strategy outperforms conventional incremental PID controllers in terms of response time and overshoot. Validated on an 11 kW experimental platform, our approach demonstrated efficient response under disturbances; with a load switch from 10 Ω to 12 Ω, the system exhibited a mere 5% fluctuation rate and an impressive efficiency of up to 92.96%. [ABSTRACT FROM AUTHOR]

Diabetic foot is a kind of limb- and life-threatening complication that is difficult to treat with conventional therapy, especially when accompanied with peripheral arterial insufficiency and severe infection. We present a diabetic patient with a postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant to almost all antibiotics. As the clinical response to antimicrobial therapy was poor, antibiotic was discontinued. Autologous platelet-rich gel with anticoagulation, negative pressure wound therapy, and improvement of microcirculation were used successfully to eradicate infection of the superbug and achieve final wound closure. [ABSTRACT FROM AUTHOR]

The article discusses a case study of a 51-year old Chinese female patient with multiple endocrine neoplasia type 1 (MEN1). The case was presented with co-existence of insulinoma and glucagonoma with germinal missense mutation. It explains the autosomal dominant familial cancer syndrome due to heterozygous germinal mutations of the MEN1 tumor suppressor gene, pancreatic or endocrine tumors and their metastases.

Aims: To explore the influence of recent high-altitude residential history on the optimal cutoff of glycosylated hemoglobin (HbA1c) for detecting abnormal glucose metabolism. Methods: The study included 505 self-reported healthy Han participants of age 18-65 years, recruited in Chengdu and categorized based on recent (within 3 months) high-altitude (>2,500 m) residential history. The 1999 WHO criteria was used as the gold standard for defining prediabetes and diabetes. HbA1c test performance was assessed using receiver operating characteristic curve, with the optimal cutoff determined by Maximum Youden index. Propensity score matching with 0.02 calipers and nearest neighbor method was used to balance confounding factors between groups. Results: Of the participants, 238 (47.13%) were populations with recent high-altitude residential history (HA group), and 267 (52.87%) were low-altitude dwellers (LA group). The HA group had slightly higher HbA1c levels ( p > 0.05) and higher erythrocyte and hemoglobin levels ( p < 0.05), compared to the LA group. Weak correlations between prediabetes and HbA1c levels were observed in the HA group ( r s = 0.21, p < 0.05) and the LA group ( r s = 0.07, p = 0.25). The optimal cutoff for the detection of diabetes was 6.5% (area under the curve [AUC] 0.94) in the HA group and 5.9% (AUC 0.97) in the LA group, which remained unchanged after adjustment for confounders. Conclusions: The optimal cutoff of HbA1c for the detection of diabetes in populations with recent history of living at high altitude was higher than that in general populations living at low altitude, and the diagnostic value of HbA1c for prediabetes was also inadequate.

Objective: To review the regulatory effect of microRNA (miRNA) in wound healing, which abnormal expression associates with diabetes., Methods: The literature on miRNA associating with wound healing was reviewed and summarized., Results: miRNA plays a key role in wound healing, including regulating inflammation, angiogenesis, granulation tissue formation, and re-epithelization., Conclusion: Abnormal expression of miRNA may be related to delayed healing of the diabetic wound, but further research is needed to confirm it.