1. Trends and Racial/Ethnic Disparities in the Rates of Pre-eclampsia by HIV Status in the US
- Author
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Vidella Coker, Muktar H. Aliyu, Hamisu M. Salihu, Collins Onyenaka, Jason L. Salemi, Deepa Dongarwar, Charlee King, Emmanuella Oduguwa, Jamalena Thompson, Oluwatoyin Bakare, Kiara K. Spooner, Omonike A. Olaleye, Sumaya Gendra, Seun Kutse, Elza Enamorado, Veronica B Ajewole, Onyinye Nwangwu, and Mayra Blanco
- Subjects
Adult ,medicine.medical_specialty ,Health (social science) ,Adolescent ,Databases, Factual ,Sociology and Political Science ,Ethnic group ,HIV Infections ,Preeclampsia ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Pre-Eclampsia ,Acquired immunodeficiency syndrome (AIDS) ,Pregnancy ,Epidemiology ,Ethnicity ,medicine ,Humans ,030212 general & internal medicine ,Pregnancy Complications, Infectious ,reproductive and urinary physiology ,Retrospective Studies ,030505 public health ,Eclampsia ,business.industry ,Health Policy ,Racial Groups ,Public Health, Environmental and Occupational Health ,Health Status Disparities ,Middle Aged ,medicine.disease ,United States ,female genital diseases and pregnancy complications ,Anthropology ,embryonic structures ,Cohort ,Female ,Hiv status ,0305 other medical science ,business ,Demography - Abstract
Preeclampsia and HIV account for a significant proportion of the global burden of disease and pose severe maternal–fetal risks. There is a dearth of literature regarding racial/ethnic disparities in preeclampsia associated with HIV/AIDS in the US. We retrospectively analyzed data from the National Inpatient Sample (NIS) database from 2002 to 2015 on a cohort of hospitalized pregnant women with or without preeclampsia and HIV. Joinpoint regression models were used to identify trends in the rates of preeclampsia among pregnant women living with or without HIV, stratified by race/ethnicity over the study period. We also assessed the association between preeclampsia and various socio-demographic factors. We analyzed over 60 million pregnancy-related hospitalizations, of which 3665 had diagnoses of preeclampsia and HIV, corresponding to a rate of 0.61 per 10,000. There was an increasing trend in the diagnosis of preeclampsia among hospitalized, pregnant women without HIV across each racial/ethnic category. The highest prevalence of preeclampsia was among non-Hispanic (NH) Blacks, regardless of HIV status. The increase in rates of pre-eclampsia between 2002 and 2015 was mostly noted among pregnant women without HIV. Regardless of HIV status, NH-Blacks experienced the highest discharge prevalence of preeclampsia.
- Published
- 2020