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13 results on '"Suleiman, Ahmed Mohamed"'

4. A conceptual framework for power generation technology management for developing countries

Author

Aljamel, Suleiman Ahmed Mohamed, Perera, Terrence, and Saad, Sameh

Subjects
333
Abstract

Most of the current approaches of technology management emphasis on the need of systematic technology management in both strategic and operational perspectives. The majority of developing countries have a problem to manage technology systematically and fail to implement management techniques effectively. There is a big gap between developed and developing countries in most fields of technology and the power generation sector is among them. The goal of this research work is to develop a conceptual framework for power generation technology management for developing countries. Also to draw a systematic guide lines and clear strategy to help decision makers to optimise their decisions to save resources and less harming to climate. In this work, a systematic approach is developed to select a suitable hard technology for power generation technologies selection using the AHP software. A sensitivity analysis is carried out to show how the decision is affected with the change in criteria and sub-criteria. After this objective is achieved, some other soft technologies are identified with their limits and integrated with hard technologies for power generation. A validation of the proposed model is provided using the questionnaire technique.

Published
2010

6. Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients

Author

Gaafar, Nuha Mohamed, primary, Osman, Tarig Al‐Hadi, additional, Ahmed, Israa Abdulrahman, additional, Elsheikh, Mariam, additional, Dongre, Harsh, additional, Jacobsen, Martha Rolland, additional, Mohamed, Nazar Gafar, additional, Fromreide, Siren, additional, Suleiman, Ahmed Mohamed, additional, Johannessen, Anne Christine, additional, Nginamau, Elisabeth Sivy, additional, and Costea, Daniela Elena, additional

Published
2021
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10. Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients.

Author

Gaafar, Nuha Mohamed, Osman, Tarig Al‐Hadi, Ahmed, Israa Abdulrahman, Elsheikh, Mariam, Dongre, Harsh, Jacobsen, Martha Rolland, Mohamed, Nazar Gafar, Fromreide, Siren, Suleiman, Ahmed Mohamed, Johannessen, Anne Christine, Nginamau, Elisabeth Sivy, and Costea, Daniela Elena

Subjects
ORAL cancer, IMMUNOHISTOCHEMISTRY, TUMOR immunology
Abstract

Background: Tumor immune infiltrate has been explored in oral squamous cell carcinoma (OSCC), but studies on simultaneous characterization of multiple immune cell subtypes separately in stromal and intraepithelial tumor compartments are limited. Objectives: We aimed to investigate the immune cell infiltrate in OSCC by using immunohistochemistry (IHC) for a panel of inflammatory cells in stromal and epithelial tumor compartments for a better characterization of the tumors. Methods: Thirty‐six OSCC lesions and nine normal oral mucosa (NOM) samples from patients attending Khartoum Dental Teaching Hospital, Sudan were investigated for presence of tumor infiltrating lymphocytes, tumor‐associated macrophages, tumor‐associated neutrophils, and PD‐L1 positive cells in the inflammatory infiltrate by single and double IHC. Digital quantitative analysis (Aperio Technologies Inc.) was performed separately for stromal and epithelial compartments. Results: OSCC cases displayed a higher inflammatory infiltrate in the associated stroma, but not in the epithelial compartment when compared to NOM. The immunosuppressive type of inflammatory infiltrate, that is, T regulatory cells (FoxP3+ cells) was identified to be significantly higher in the epithelial compartment of tumors with advanced clinical state. An immunoscore developed by combining intraepithelial FoxP3+ and CD4+ cells was found significantly higher in lesions from elderly patients, localized at toombak dipping‐related sites, poorly differentiated OSCCs, or with loco‐regional lymph node spreading. Conclusions: Despite heavy immune cell infiltration in tumor‐associated stroma, the majority of OSCCs in this cohort displayed a low intraepithelial immune infiltration. An immunoscore based on combined CD4 and FoxP3 intraepithelial expression may serve as an indicator of advanced tumor progression and should be further investigated for its use as potential prognostic biomarker in OSCC. [ABSTRACT FROM AUTHOR]

Published
2022
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13. A conceptual framework for power generation technology management for developing countries

Author

Aljamel, Suleiman Ahmed Mohamed., Perera, Terrence, and Saad, Sameh

Abstract

Most of the current approaches of technology management emphasis on the need of systematic technology management in both strategic and operational perspectives. The majority of developing countries have a problem to manage technology systematically and fail to implement management techniques effectively. There is a big gap between developed and developing countries in most fields of technology and the power generation sector is among them. The goal of this research work is to develop a conceptual framework for power generation technology management for developing countries. Also to draw a systematic guide lines and clear strategy to help decision makers to optimise their decisions to save resources and less harming to climate. In this work, a systematic approach is developed to select a suitable hard technology for power generation technologies selection using the AHP software. A sensitivity analysis is carried out to show how the decision is affected with the change in criteria and sub-criteria. After this objective is achieved, some other soft technologies are identified with their limits and integrated with hard technologies for power generation. A validation of the proposed model is provided using the questionnaire technique.

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