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Your search keyword '"Sugahara, Takaya"' showing total 11 results
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11 results on '"Sugahara, Takaya"'

1. A reductively convertible nickel phthalocyanine precursor as a biological thiol-responsive turn-on photoacoustic contrast agent.

Author

Nogita, Kohei, Sugahara, Takaya, Miki, Koji, Mu, Huiying, Kobayashi, Minoru, Harada, Hiroshi, and Ohe, Kouichi

Abstract

A nickel phthalocyanine precursor bearing poly(ethylene glycol) as a turn-on contrast agent for photoacoustic imaging was prepared. The water-soluble polymeric chains were smoothly eliminated through thiol-mediated reductive aromatization in cancer cells, enabling the detection of endogenous biological thiols in vitro and in vivo. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Cloning and nucleotide sequence of the carboxynorspermidine decarboxylase gene from Vibrio alginolyticus

Author

Yamamoto, Shigeo, Sugahara, Takaya, Tougou, Katsuhiko, and Shinoda, Sumio

Subjects
Decarboxylases -- Genetic aspects, Microbiological synthesis -- Analysis, Vibrio -- Research, Biological sciences
Abstract

Immuno-screening method enables the isolation of the gene encoding the pyridoxal 5'-phosphate-dependent carboxynorspermidine decarboxylase from Vibrio alginolyticus. The enzyme is responsible for the last catalytic-step in the norspermidine biosynthesis. Sequential analysis helps characterize the gene and the amino acid sequence is compared with those of other bacterial decarboxylases. Southern hybridization uses a part of the cloned DNA of the gene to analyze homologous sequences in other Vibrio species.

Published
1994

11. 3D Visualization of Liquid Water in Catalyst Layer Using X-Ray CT

Author

Sugahara, Takaya, Sasabe, Takashi, Naito, Hiroshi, Kodama, Manabu, and Hirai, Shuichiro

Abstract

To clarify the behavior of liquid water in polymer electrolyte fuel cell (PEFC), X-ray computed tomography (XTM) is used. In the past, 3D visualization experiments of liquid water in substrate layer and microporous layer (MPL) were conducted. However, 3D visualization of liquid water in catalyst layer (CL) has not been conducted yet. It is important to clarify liquid water in CL because water is generated in CL. We improved two things. First, we used the CL with low platinum percentage because its X-ray absorption coefficient is low. Second, 20.5-hour CT scan was conducted to improve spatial resolution. Therefore, we succeeded the detection of liquid water in CL.

Published
2022
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