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1. Management of Fetal Hydrops due to Maternal Antibodies against a Low Incidence Paternal Red Cell Antigen: A Novel Insight from Clinical Practice

Author

Joyce Poole, Edwin Massey, Alison Hills, John Moppett, Stephen W. Jones, Timothy Overton, and Sue Search

Subjects
Adult, Male, Middle Cerebral Artery, Embryology, medicine.medical_specialty, Hydrops Fetalis, Exchange Transfusion, Whole Blood, Blood Transfusion, Intrauterine, Disease, Ultrasonography, Prenatal, Antigen, Pregnancy, Fetal hydrops, medicine.artery, medicine, Humans, Radiology, Nuclear Medicine and imaging, Fetus, Red Cell, biology, Anemia, Neonatal, business.industry, Obstetrics, Incidence (epidemiology), Infant, Newborn, Obstetrics and Gynecology, General Medicine, Pedigree, Pediatrics, Perinatology and Child Health, Middle cerebral artery, Immunology, Blood Group Antigens, biology.protein, Female, Anemia, Hemolytic, Autoimmune, Antibody, business
Abstract

A rare case of a low incidence red cell antigen causing severe fetal allo-immune red cell disease is presented. Discussion of how this can be diagnosed and successfully managed antenatally using middle cerebral artery Doppler ultrasound and maternal antibody titre levels for fetal surveillance and timing of intervention with intrauterine transfusion.

Published
2012
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