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1. Ribosomal oxygenases are structurally conserved from prokaryotes to humans

2. Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

3. Precision is essential for efficient catalysis in an evolved Kemp eliminase

4. Natural and anthropogenic substrates affect movement behavior of the Southern Graycheek Salamander (Plethodon metcalfi)

5. Large-scale identification and translocation of type IV secretion substrates by Coxiella burnetii

6. Phosphorylated Rad l8 directs DNA Polymerase to sites of stalled replication

7. Substrate specificity of Rhbg: ammonium and methyl ammonium transport

8. Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation

9. Postreplication gaps at UV lesions are signals for checkpoint activation

10. Costs and constraints from time-delayed feedback in small gene regulatory motifs

11. Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase

12. Substrate-enhanced supercooling in AuSi eutectic droplets

13. Crystal structure of the FTO protein reveals basis for its substrate specificity

14. DNA as a universal substrate for chemical kinetics

15. Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate

16. Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role

17. Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLC[gamma]l

18. Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase

19. Paddling mechanism for the substrate translocation by AAA+ motor revealed by multiscale molecular simulations

20. Substrate positioning controls the partition between halogenation and hydroxylation in the aliphatic halogenase, SyrB2

21. Chemoenzymatic elaboration of monosaccharides using engineered cytochrome [P450.sub.BM3] demethylases

22. Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution

23. Crystal structures of Streptococcus suis mannonate dehydratase (ManD) and its complex with substrate: genetic and biochemical evidence for a catalytic mechanism

24. Molecular basis of substrate selection by the n-end rule adaptor protein CIpS

25. Effects of Si[O.sub.2] addition in FePt on microstructures and magnetic properties on two different MgO substrates

26. Development of a phase-controlled constant-distance scanning electrochemical microscope

27. Organic photodiodes for biosensor miniaturization

28. Protein-mediated sandwich strategy for surface-enhanced Raman scattering: application to versatile protein detection

29. Electrochemical and chemical microfluidic gold etching to generate patterned and gradient substrates for cell adhesion and cell migration

30. Indirect broadband optical monitoring with multiple witness substrates

31. Elucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approaches

32. Substrate thickness error and radial tilt detection using a five-beam optical head

33. Structural plasticity of an acid-activated chaperone allows promiscuous substrate binding

34. Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation

35. Generation of hyperpolarized substrates by secondary labeling with [1,1-[sup.13]C] acetic anhydride

36. Phosphorylation of IRS proteins, insulin action, and insulin resistance

37. Self-assembled peptide monolayers as a toxin sensing mechanism within arrayed microchannels

38. Effects of intracerebroventricular and intra-accumbens melanin-concentrating hormone agonism on food intake and energy expenditure

39. The cavity-chaperone Skp protects its substrate from aggregation but allows independent folding of substrate domains

40. The substrate-binding protein imposes directionality on an electrochemical sodium gradient-driven TRAP transporter

41. Myocardial FFA metabolism during rest and atrial pacing in humans

42. The mechanism of transport by mitochondrial carriers based on analysis of symmetry

43. Off-line coupling of capillary electrophoresis to substrate-assisted laser desorption inductively coupled plasma mass spectrometry

44. Cation-assisted laser desorption/ionization for matrix-free surface mass spectrometry of alkanethiolate self-assembled monolayers on gold substrates and nanoparticles

47. Global protein stability profiling in mammalian cells

48. Protein kinase PKR mutants resistant to the poxvirus pseudosubstrate K3L protein

49. Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure

50. Substrate-induced changes in the density of peptide transporter PEPT1 expressed in Xenopus oocytes

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