58 results on '"Subhajit Chakraborty"'
Search Results
2. Digital Quality's Role in Us Online Higher Education
- Author
-
Subhajit Chakraborty
- Abstract
Purpose: The emergence of internet-based business models has given rise to online higher education institutions (OHEIs) that offer their undergraduate and graduate degree programs exclusively online with minimal physical presence. Research on OHEIs discusses the need for external legitimacy and resource acquisition, often ignoring the role of quality among these institutions. Hence, this study aims to investigate the role of digital quality of education on OHEIs' survival. Design/methodology/approach: Guided by four different inter-disciplinary theories, a conceptual framework is offered based on a comprehensive literature review. Findings: The role of digital quality of education in improving the survival and strategic competitiveness of institutions in the US online higher education industry is highlighted. Research limitations/implications: This conceptual paper highlights how the digital quality of education becomes increasingly important over the life cycle of OHEIs. Practical implications: The proposed framework suggests that despite the competition provided by traditional and well-entrenched players, OHEIs can improve their survival and competitiveness if they invest strategically in the digital quality of education. Originality/value: This study offers an overarching conceptual framework developed through an integration of multiple theoretical perspectives and grounded in the US online higher education industry.
- Published
- 2024
- Full Text
- View/download PDF
3. N-Alkylation of Amines by C1–C10 Aliphatic Alcohols Using A Well-Defined Ru(II)-Catalyst. A Metal–Ligand Cooperative Approach
- Author
-
Amit Kumar Guin, Subhasree Pal, Subhajit Chakraborty, Santana Chakraborty, and Nanda D. Paul
- Subjects
Organic Chemistry - Published
- 2023
4. Zn(II)-Catalyzed Multicomponent Sustainable Synthesis of Pyridines in Air
- Author
-
Subhasree Pal, Siuli Das, Subhajit Chakraborty, Subhankar Khanra, and Nanda D. Paul
- Subjects
Organic Chemistry - Published
- 2023
5. Biology of Coital Behavior: Looking Through the Lens of Mathematical Genomics
- Author
-
Moumita Sil, Debaleena Nawn, Sk. Sarif Hassan, Subhajit Chakraborty, Arunava Goswami, Pallab Basu, Lalith Roopesh, Emma Wu, Kenneth Lundstrom, and Vladimir N. Uversky
- Abstract
Research has shown that genetics and epigenetics regulate mating behavior across multiple species. Previous studies have generally focused on the signaling pathways involved and spatial distribution of the associated receptors. However a thorough quantitative characterization of the receptors involved may offer deeper insight into mating behavioral patterns. Here oxytocin, arginine-vasopressin 1a, dopamine 1, and dopamine 2 receptors were investigated across 76 vertebrate species. The receptor sequences were characterized by polarity-based randomness, amino acid frequency-based Shannon entropy and Shannon sequence variability, intrinsic protein disorder, binding affinity, stability and pathogenicity of homology-based SNPs, structural and physicochemical features. Hierarchical clustering of species was derived based on structural and physicochemical features of the four receptor sequences separately, which eventually led to proximal relationships among 29 species. Humans were found to be significantly distant phylogenetically from the prairie voles, a representative of monogamous species based on coital behavior. Furthermore, the mouse (polygamous), the prairie deer mouse (polygamous), and the prairie vole (monogamous) although being proximally related (based on quantitative genomics of receptors), differed in their coital behavioral pattern, mostly, due to behavioral epigenetic regulations. This study adds a perspective that receptor genomics does not directly translate to behavioral patterns.
- Published
- 2023
6. Wurtzite CuGaS 2 with an In‐Situ‐Formed CuO Layer Photocatalyzes CO 2 Conversion to Ethylene with High Selectivity
- Author
-
Subhajit Chakraborty, Risov Das, Mohd Riyaz, Kousik Das, Ashutosh Kumar Singh, Debabrata Bagchi, Chathakudath P. Vinod, and Sebastian C. Peter
- Subjects
General Chemistry ,General Medicine ,Catalysis - Abstract
We present surface reconstruction-induced C-C coupling leads to conversion of CO2 to Ethylene. Wurtzite phase of CuGaS2. undergoes in-situ surface reconstruction leads to the formation of a thin CuO layer over the pristine catalyst which facilitates selective conversion of CO2 to ethylene (C2H4). Upon illumination, the catalyst efficiently converts CO2 to C2H4 with 75.1% selectivity (92.7% selectivity in terms of Relectron) and 20.6 µmol g-1 h-1 evolution rate. Subsequent spectroscopic and microscopic studies supported by theoretical analysis found the operando generated Cu2+ with the assistance of existing Cu+anchored the generated *CO, facilitating the C-C coupling. This study demonstrates the strain-induced in-situ surface reconstruction leading to heterojunction formation accounting for fine-tuning of the oxidation state of Cu that modulate CO2 reduction reaction pathway to selective formation of ethylene, which opens a new footstep to achieve CO2 to C2+ hydrocarbons.
- Published
- 2023
7. Mechanistic aspects of reversible methylation modifications of arginine and lysine of nuclear histones and their roles in human colon cancer
- Author
-
Ankan Roy, null Niharika, Subhajit Chakraborty, Jagdish Mishra, Suraj Pratap Singh, and Samir Kumar Patra
- Published
- 2023
8. Epigenetic regulation of pluripotency inducer genes NANOG and SOX2 in human prostate cancer
- Author
-
null Niharika, Ankan Roy, Jagdish Mishra, Subhajit Chakraborty, Suraj Pratap Singh, and Samir Kumar Patra
- Published
- 2023
9. Iron-Catalyzed Metal–Ligand Cooperative Approach toward Sustainable Synthesis of Azines and N-Acylhydrazones in Air
- Author
-
Rakesh Mondal, Amit Kumar Guin, Subhajit Chakraborty, and Nanda D. Paul
- Subjects
Organic Chemistry - Published
- 2022
10. Effects of protecting groups on luminescent metal nanoclusters: spectroscopic signatures and applications
- Author
-
Saptarshi Mukherjee and Subhajit Chakraborty
- Subjects
Materials science ,Metal ions in aqueous solution ,Metal Nanoparticles ,Nanotechnology ,Protective Agents ,behavioral disciplines and activities ,Catalysis ,Nanoclusters ,Metal ,mental disorders ,Materials Chemistry ,Fluorescent Dyes ,Ligand ,Temperature ,Metals and Alloys ,General Chemistry ,Hydrogen-Ion Concentration ,Biocompatible material ,Small molecule ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Spectrometry, Fluorescence ,X-Ray Absorption Spectroscopy ,Template ,visual_art ,Ceramics and Composites ,visual_art.visual_art_medium ,Gold ,Luminescence - Abstract
Luminescent metal nanoclusters (NCs) have been established as next-generation fluorophores. Their biocompatible and non-toxic nature, along with excellent chemical- and photo-stability, enables them to find applications in multi-disciplinary areas. However, preparing NCs which are stable is always challenging, primarily owing to their small size and propensity to self-aggregate. In this review, we highlight a holistic approach as to how ligands and templates can monitor the stability of NCs, tune their spectroscopic signatures, and alter their applications. The role of small molecules of a large ligand in the preparation of NCs and their associated limitations are also discussed. We have summarized how these NCs can be utilized in sensing several metal ions, pH, viscosity and temperature of many systems which have biological relevance. Additionally, these luminescent metal NCs find usage in cell-imaging, discriminating between cancerous and non-cancerous cell lines and also targeting specific organelles within the cellular environment.
- Published
- 2022
11. Zn(II)-Catalyzed Selective
- Author
-
Subhajit, Chakraborty, Rakesh, Mondal, Subhasree, Pal, Amit Kumar, Guin, Lisa, Roy, and Nanda D, Paul
- Abstract
We report a sustainable and eco-friendly approach for selective
- Published
- 2022
12. The strategic value of servitization: A quality management perspective
- Author
-
Muratcan Erkul, Hale Kaynak, and Subhajit Chakraborty
- Subjects
Typology ,Quality management ,Value (economics) ,Perspective (graphical) ,Manufacturing firms ,Business ,General Business, Management and Accounting ,Industrial organization - Abstract
We propose a typology suggesting varying extent of servitization for manufacturing firms in different industries that could help them improve their firm performance. We suggest that contemporary ma...
- Published
- 2021
13. Systematic Assessment of Solvent Selection in Photocatalytic CO2 Reduction
- Author
-
Subhajit Chakraborty, Sebastian C. Peter, and Risov Das
- Subjects
Reduction (complexity) ,Solvent ,Fuel Technology ,Materials science ,Chemical engineering ,Renewable Energy, Sustainability and the Environment ,Chemistry (miscellaneous) ,Materials Chemistry ,Photocatalysis ,Energy Engineering and Power Technology ,Selection (genetic algorithm) - Published
- 2021
14. Tyrosine-Templated Dual-Component Silver Nanomaterials Exhibit Photoluminescence and Versatile Antimicrobial Properties through ROS Generation
- Author
-
Preeti Sagarika, Saptarshi Mukherjee, Chandan Sahi, Saurabh Rai, and Subhajit Chakraborty
- Subjects
Antifungal Agents ,Silver ,Materials science ,Reducing agent ,Metal Nanoparticles ,Microbial Sensitivity Tests ,Saccharomyces cerevisiae ,Silver nanoparticle ,Nanomaterials ,chemistry.chemical_compound ,Bacillus cereus ,Candida albicans ,Escherichia coli ,General Materials Science ,Luminescent Agents ,Singlet Oxygen ,biology ,Singlet oxygen ,Ligand (biochemistry) ,Antimicrobial ,biology.organism_classification ,Combinatorial chemistry ,Small molecule ,Anti-Bacterial Agents ,chemistry ,Tyrosine - Abstract
The role of small molecules in the preparation of metal nanomaterials generates considerable interest in the fields from materials science to interdisciplinary sciences. In this study, a small amino acid, l-tyrosine (Tyr), has been used as a ligand precursor for the preparation of silver nanomaterials (AgNMs) comprising a dual system: smaller silver nanoclusters (responsible exclusively for the photophysical properties) and larger silver nanoparticles (responsible exclusively for the antimicrobial properties). The luminescent properties of this AgNM system substantiate the role played by Tyr as a capping and a reducing agent outside the protein environment. An interesting feature of this report is the promising antimicrobial properties of the AgNMs against Saccharomyces cerevisiae, Candida albicans, Escherichia coli, and Bacillus cereus cell lines. The importance of this work is that this investigation demonstrates the combating ability of our AgNM system against pathogenic strains (C. albicans and B. cereus) as well. Moreover, the mechanistic aspects of the antimicrobial activity of the AgNMs were elucidated using various methods, such as propidium iodide staining, monitoring reactive oxygen species generation, leakage of proteins, DNA cleavage, etc. We propose that AgNM-mediated cytotoxicity in S. cerevisiae stems from the generation of singlet oxygen (1O2) species that create oxidative stress, disrupting the cell membrane and thereby resulting in leakage of proteins from the cells. This study can pave the way toward elucidating the role of a small molecule, Tyr, in the formation of NMs and describes the use of new NMs in potential antimicrobial applications.
- Published
- 2021
15. Patient hospital experience and satisfaction on social media
- Author
-
Subhajit Chakraborty and E. Mitchell Church
- Subjects
Quality management ,030503 health policy & services ,media_common.quotation_subject ,Grounded theory ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,Nursing ,Action (philosophy) ,Perception ,Business, Management and Accounting (miscellaneous) ,Social media ,Narrative ,030212 general & internal medicine ,0305 other medical science ,Psychology ,media_common ,Health care quality - Abstract
Purpose The purpose of this paper is to show the value of open-ended narrative patient reviews on social media for elucidating aspects of hospital patient satisfaction. Design/methodology/approach Mixed methods analyses using qualitative (manual content analyses using grounded theory and algorithmic analyses using the Natural Language Toolkit) followed by quantitative analyses (negative binomial regression). Findings Health-care team communication, health-care team action orientation and patient hospital room environment are positively related to patient hospital satisfaction. Patients form their hospital satisfaction perceptions based on the three facets of their hospital stay experience. Research limitations/implications In the spirit of continuous quality improvement, periodically analyzing patient social media comments could help health-care teams understand the patient satisfaction inhibitors that they need to avoid to offer patient-centric care. Practical implications By periodically analyzing patient social media comments hospital leaders can quickly identify the gaps in their health service delivery and plug them, which could ultimately give the hospital a competitive advantage. Originality/value To the best of the authors’ knowledge, this is one of the first studies to apply mixed methods to patient hospital review comments given freely on social media to critically understand what drives patient hospital satisfaction ratings.
- Published
- 2021
16. Looking Outwards and Inwards to Improve Patient Care Quality and Clinical Outcomes in U.S. Hospitals
- Author
-
Subhajit Chakraborty
- Subjects
General Medicine - Published
- 2022
17. Possible Functional Proximity of Various Organisms Based on Taste Receptors Genomics
- Author
-
Sk. Sarif Hassan, Moumita Sil, Subhajit Chakraborty, Arunava Goswami, Pallab Basu, Debaleena Nawn, and Vladimir N. Uversky
- Abstract
Taste is one of the essential senses in providing the organism a faithful representation of the external world. Taste perception is responsible for basic food and drink appraisal and bestows the organism with valuable discriminatory power. Umami and sweet are “good” tastes that promote consumption of nutritive food, whereas bitter and sour are “bad” tastes that alert the organism to toxins and low pH, promoting rejection of foods containing harmful substances. Not every animal has the same sense of taste as humans. Variation in the taste receptor genes contributes to inter and intra organism differences of taste (sweet/bitter) sensation and preferences. Therefore a deeper understanding was needed to comprehend taste perception by various vertebrates and accordingly elucidate a possible proximity among them. In this study, a total 20 Type-1 (sweet) and 189 Type-2 (bitter) taste receptor complete-amino acid sequences were taken from the 20 vertebrate organisms (18 mammalian, 1 aves, and 1 amphibian). Among 10 primates, 8 including humans were very close based on genomics of taste receptors and rodent organisms viz. the rat and mouse were away from them. This investigation throws light on the similitude and dissimilitude of perception of sweet and bitter taste among 20 different organisms, steered by quantitative analysis of their genomic data. Furthermore, it enlightened that ligand binding affinity of sweet/bitter taste molecules in the taste receptors of any proximal pair of organisms would be similar.
- Published
- 2022
18. Possible functional proximity of various organisms based on the bioinformatics analysis of their taste receptors
- Author
-
Sk. Sarif Hassan, Moumita Sil, Subhajit Chakraborty, Arunava Goswami, Pallab Basu, Debaleena Nawn, and Vladimir N. Uversky
- Subjects
Primates ,Mammals ,Computational Biology ,Taste Perception ,General Medicine ,Taste Buds ,Biochemistry ,Rats ,Mice ,Structural Biology ,Taste ,Humans ,Animals ,Molecular Biology - Abstract
Taste is one of the essential senses in providing the organism a faithful representation of the external world. Taste perception is responsible for basic food and drink appraisal and bestows the organism with valuable discriminatory power. Umami and sweet are "good" tastes that promote consumption of nutritive food, whereas bitter and sour are "bad" tastes that alert the organism to toxins and low pH, promoting rejection of foods containing harmful substances. Not every animal has the same sense of taste as humans. Variation in the taste receptor genes contributes to inter and intra organism differences of taste (sweet/bitter) sensation and preferences. Therefore a deeper understanding was needed to comprehend taste perception by various vertebrates and accordingly elucidate a possible proximity among them. In this study, a total 20 Type-1 (sweet) and 189 Type-2 (bitter) taste receptor complete-amino acid sequences were taken from the 20 vertebrate organisms (18 mammalian, 1 Aves, and 1 amphibian). Among 10 primates, 8 including humans were very close based on genomics of taste receptors and rodent organisms viz. the rat and mouse were away from them. This investigation throws light on the similitude and dissimilitude of perception of sweet and bitter taste among 20 different organisms, steered by quantitative analysis of their genomic data. Furthermore, it enlightened that ligand binding affinity of sweet/bitter taste molecules in the taste receptors of any proximal pair of organisms would be similar.
- Published
- 2022
19. Erratum - Nickel-Catalyzed Sustainable and Selective Alkylation of Alcohols to α-Alkylated Ketones via Borrowing Hydrogen Approach
- Author
-
Nanda D. Paul, Gargi Chakraborty, Subhasree Pal, and Subhajit Chakraborty
- Subjects
Organic Chemistry - Published
- 2023
20. Role of service characteristics in determining the degree of customer involvement: a typology.
- Author
-
Subhajit Chakraborty and Hale Kaynak
- Published
- 2014
- Full Text
- View/download PDF
21. Exploring the impact of decentralized leadership on knowledge sharing and work hindrance networks in healthcare teams
- Author
-
Cara-Lynn Scheuer, Kothai Kumanan, Annika Voltan, and Subhajit Chakraborty
- Subjects
Organizational Behavior and Human Resource Management ,Knowledge management ,business.industry ,030503 health policy & services ,05 social sciences ,Knowledge sharing ,03 medical and health sciences ,Work (electrical) ,0502 economics and business ,Health care ,Sociology ,Business and International Management ,0305 other medical science ,business ,050203 business & management - Abstract
This paper adopts an explanatory sequential mixed method design to explore the impact of decentralized (vs. centralized) leadership on cross-functional teams' resource exchanges at a long-term care facility in Canada. In the quantitative phase, social network analyses were used to examine the direct and moderated effects (via leader–follower relationship quality; LMX) of the presence of formal decentralized leaders on: (1) knowledge sharing, and (2) work hindrance networks within cross-functional healthcare teams. In the qualitative phase, team members were interviewed regarding the impact of their decentralized leaders. Collectively, the findings suggest that the presence of a decentralized leader may enhance knowledge sharing and safeguard against work hindrance behaviors in cross-functional healthcare teams. However, these effects are contingent on the situation (e.g., LMX quality and status-based hierarchies). Implications for research and healthcare practice are discussed.
- Published
- 2021
22. Protein-templated gold nanoclusters as specific bio-imaging probes for the detection of Hg(<scp>ii</scp>) ions in in vivo and in vitro systems: discriminating between MDA-MB-231 and MCF10A cells
- Author
-
Atanu Nandy, Sunando Datta, Saptarshi Mukherjee, Subhajit Chakraborty, Sameena Parveen, Subhadip Ghosh, and Nirmal Kumar Das
- Subjects
Metal ions in aqueous solution ,Metal Nanoparticles ,Fluorescence correlation spectroscopy ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Biochemistry ,Analytical Chemistry ,Nanoclusters ,law.invention ,Confocal microscopy ,law ,Electrochemistry ,medicine ,Humans ,Environmental Chemistry ,Spectroscopy ,Ions ,Detection limit ,Chemistry ,Mercury ,021001 nanoscience & nanotechnology ,Human serum albumin ,Fluorescence ,0104 chemical sciences ,Spectrometry, Fluorescence ,Biophysics ,Gold ,0210 nano-technology ,Luminescence ,medicine.drug - Abstract
Gold nanoclusters (AuNCs) synthesized within a protein (Human Serum Albumin, HSA) template exhibited intense red luminescence accompanied by a quantum yield >10% and remarkable photo and cluster-core stability for a prolonged period (more than a year). These photoluminescent nanoclusters (NCs) were resistant to chemical and thermal perturbations but break down selectively and highly sensitively in the presence of mercury, Hg(ii), ions. The AuNCs were efficient in quantifying Hg(ii) ions in solution as well as bound to the hormone insulin. By exploiting the auto-fluorescence of these AuNCs, we demonstrated that our AuNCs were able to sense Hg(ii) ions at single-molecule sensitivity using Fluorescence Correlation Spectroscopy (FCS), highlighting a detection limit in the sub-nanomolar regime. The translational diffusion time of the AuNCs decreased significantly upon the interaction with Hg(ii) ions and resulted in the formation of smaller sized clusters. A cell viability study reveals the non-toxic nature of these nano-probes, which thus can be used for cell imaging. Interestingly, a cell line-based study reveals that the fluorescence intensity of AuNCs could be detected in cancerous MDA-MB-231 cells but not in non-cancerous breast-derived MCF10A cells. Further, time lapse fixed cell imaging by confocal microscopy revealed that the fluorescence of AuNCs could be quenched by Hg(ii) ions inside the MDA-MB-231 cells. Thus the objective of our study is to appraise the sensitive in vivo as well as in vitro detection of Hg(ii) ions using AuNCs as a probe.
- Published
- 2021
23. Investigating the pH dependence of thermal signatures in monohydric and polyhydric alcohols using time-resolved thermal lens spectroscopy
- Author
-
Ashwini Kumar Rawat, Subhajit Chakraborty, Amit Kumar Mishra, and Debabrata Goswami
- Subjects
Inorganic Chemistry ,Organic Chemistry ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,Atomic and Molecular Physics, and Optics ,Spectroscopy ,Electronic, Optical and Magnetic Materials - Published
- 2023
24. Diluting Convective Effects in Femtosecond Laser Induced Thermal Lens Measurements with Thermally Active Constituents
- Author
-
Subhajit Chakraborty, Amit Kumar Mishra, Ashwini Kumar Rawat, and Debabrata Goswami
- Abstract
We report Thermal Lens measurements on the binary liquid mixtures of Methanol and Phenol with femtosecond pulse excitations. The photothermal response is found to be strongly dependent on relative concentrations and the constituents’ molecular properties.
- Published
- 2022
25. Exploring the Role of Merchant Banker as Capital Market Intermediary: With Special Reference to Role Played Under Stock Market
- Author
-
Subhajit Chakraborty and Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP)
- Subjects
promoting, finance, intermediary, capital market, merchant banker ,Stock market ,Business ,Monetary economics ,J10160641020/2020©BEIESP ,Capital market ,2394-0913 - Abstract
For smooth and effective governance of corporate organizations and to achieve a sustainable development in the corporate fraternity, organizations require finance both for financing the fixed capital as well as for working capital. Finance is such an important aspect of business that enterprises cannot sustain without its interference and as such right from its incorporation till it’s winding up finance occupies a pivotal position. It is not only for the small and big enterprises which requires finance but also the entire economic structure of the country keeps reliance on it. As corporate sector contributes towards Indian economy about 53 % of Gross Domestic Product, the role of security market under the cloak of Security Exchange Board of India plays an important role in contributing to the Indian Economy. Security market also known as the stock market is a platform where a company can raise its fund or share-capital through the means of various kinds of marketable and financial instruments carrying voting rights, interest and payment of dividend both at domestic and international level. For a sustainable corporate governance, a compliance framework has to be established which will help and support the risk management system during identifying the sources of corporate funding and the pools of fund both from domestic capital market and international markets. Corporates should first create an established framework which will help them to evaluate and assess their financial requirement to the extent of managing funds from various sources. It is true that a company issues securities to the investors through the mechanism of initial public offering and further public offering in primary market and in furtherance such securities are additionally traded in secondary market through the platform of recognized stock exchange which makes it crystal clear that there is no direct congruence or connection between the issuer company and the security holders. In this gap the role played by the intermediaries are pertinent for the operations relating to issuance and trading of securities and as such merchant banker is one of the key intermediary in capital market appointed by the issuer company for public issue management. The paper will focus on the role played by the merchant banker in primary market. It will also attempt to define how the merchant banker functions with due regard to public issue management, credit rating of shares and how it complies with the changing laws and regulations for an effective management of corporate transactions.
- Published
- 2020
26. Probing Viscosity of Co‐Polymer Hydrogel and HeLa Cell Using Fluorescent Gold Nanoclusters: Fluorescence Correlation Spectroscopy and Anisotropy Decay
- Author
-
Somen Nandi, Saptarshi Mukherjee, Kankan Bhattacharyya, and Subhajit Chakraborty
- Subjects
Materials science ,Polymers ,Metal Nanoparticles ,Fluorescence correlation spectroscopy ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Micelle ,Nanoclusters ,Live cell imaging ,Copolymer ,Humans ,Physical and Theoretical Chemistry ,Anisotropy ,Fluorescent Dyes ,Viscosity ,Optical Imaging ,technology, industry, and agriculture ,Hydrogels ,021001 nanoscience & nanotechnology ,Fluorescence ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Spectrometry, Fluorescence ,Biophysics ,Gold ,0210 nano-technology ,Fluorescence anisotropy ,HeLa Cells - Abstract
Fluorescence dynamics of gold nanoclusters (Au9 and Au25 ) are studied in the complex and crowded environment of a triblock co-polymer (F127) hydrogel and inside cervical cancer cell, HeLa. In the hydrogel, spherical micelles of F127 remain immobilized with a hydrophobic core (PPO) and a hydrophilic corona (PEO) region. The fluorescence anisotropy decay suggests that the timescale of rotational relaxation in the hydrogel is similar to that in bulk water (viscosity ∼1 cP). From fluorescence correlation spectroscopy (FCS) it is inferred that the local viscosity in the hydrogel is 12 cP for Au9 and 18 cP for Au23 . These results indicate that gold nanoclusters (AuNCs) localize in the corona region of the hydrogel. Evidently, frictions against rotation and translation are different inside the gel. It is suggested that rotation of the AuNCs senses the immediate water-like "void" region while translation motion involves in-and-out movement of the AuNCs at the periphery of the gel. Finally, the gold nanoclusters are used for cell imaging and estimation of intracellular viscosity of HeLa cells.
- Published
- 2020
27. Tyrosine-Templated Dual-Component Silver Nanomaterials Exhibit Photoluminescence and Versatile Antimicrobial Properties through ROS Generation
- Author
-
SUBHAJIT CHAKRABORTY
- Published
- 2021
28. Achieving molecular distinction in alcohols with femtosecond thermal lens spectroscopy
- Author
-
Ashwini Kumar Rawat, Subhajit Chakraborty, Amit Kumar Mishra, and Debabrata Goswami
- Subjects
General Physics and Astronomy ,Physical and Theoretical Chemistry - Published
- 2022
29. Nickel-Catalyzed Sustainable and Selective Alkylation of Alcohols to α-Alkylated Ketones via Borrowing Hydrogen Approach
- Author
-
Nanda D. Paul, Gargi Chakraborty, Subhasree Pal, and Subhajit Chakraborty
- Subjects
Organic Chemistry - Abstract
Herein, we report a nickel-catalyzed sustainable, environment-friendly, and economically affordable borrowing hydrogen approach (BHA) for synthesizing various α-alkylated ketones via dehydrogenative coupling of primary and secondary alcohols. Using a well-defined, air-stable, inexpensive, and easy-to-prepare four-coordinate macrocyclic Ni(II)-catalyst [Ni(MeTAA)] of a tetra-aza macrocyclic ligand (tetramethyltetraaza[14]annulene (H2MeTAA)), a series of α-alkylated ketones were prepared in good yields. A few control reactions, including deuterium-labelling experiments, were performed to unveil the reaction mechanism.
- Published
- 2022
30. Poly-lysinated nanoscale carbon probe for low power two-photon bioimaging
- Author
-
Niranjan Chatterjee, Santosh K. Misra, Subhajit Chakraborty, Arjit Gupta, Debabrata Goswami, and SAYAN Kundu
- Subjects
Photons ,Photobleaching ,Instrumentation ,Carbon ,Fluorescence ,Spectroscopy ,Atomic and Molecular Physics, and Optics ,Fluorescent Dyes ,Analytical Chemistry - Abstract
Effective outcome from dynamic live-cell-imaging requires utilization of a probe with high emission intensity and low photobleaching. It would be preferable to achieve such properties at a low power of the applied laser to avoid any probable damage to biological cells or tissue. Most of the used small-molecule fluorophores have been reported to show significant photobleaching in a time-dependent manner and require high laser power to gain significant intensity for bioimaging. Carbon nanoparticles have recently been successfully used for cell imaging with low bleaching characteristics but require high laser power and lack optical nonlinearity at low power levels. Here, we report the preparation, characterization, and application of a Nanoscale Carbon (NC) which, on being surface decorated with crescent-shaped poly-lysine (PLNC), provides two-photon fluorescence (TPF) and low bleaching properties. PLNC was found to stain the cytoplasm of C2C12 muscle cells in the first four-hours of incubation with high TPF in the infrared range and can be useful for deep tissue imaging with further improvements.
- Published
- 2022
31. Role of Small Moiety of a Large Ligand: Tyrosine Templated Copper Nanoclusters
- Author
-
Subhajit Chakraborty and Saptarshi Mukherjee
- Subjects
Reducing agent ,Metal Nanoparticles ,Biocompatible Materials ,02 engineering and technology ,010402 general chemistry ,Photochemistry ,Ligands ,01 natural sciences ,Nanoclusters ,Metal ,Moiety ,General Materials Science ,Physical and Theoretical Chemistry ,Density Functional Theory ,chemistry.chemical_classification ,Ligand ,021001 nanoscience & nanotechnology ,Small molecule ,0104 chemical sciences ,Amino acid ,Spectrometry, Fluorescence ,chemistry ,visual_art ,visual_art.visual_art_medium ,Tyrosine ,0210 nano-technology ,Luminescence ,Copper - Abstract
To explore the underlying formation mechanism of luminescent metal nanoclusters (NCs) using a small moiety such as amino acids (outside the milieu of a protein environment) as templates, herein we report blue-emitting copper nanoclusters (CuNCs) using l-tyrosine (l-Tyr) as a capping agent as well as a reducing agent. We also demonstrate the effect of an in situ fibrillation of Tyr on the luminescence and structural properties of NCs. Fluorescence studies along with microscopic imaging revealed the rapid formation of a dityrosine (di-Tyr) moiety in an alkaline medium followed by an aggregated "Tamarix dioica leaf"-like fibrillar pattern along with CuNCs. Our present investigation delineates the role played by π-π interactions in the formation of the fibrillar structures. We substantiated the fundamentals of using a small molecule of a large ligand that can serve as a template and also show how these NCs once formed destroy the fibrils of di-Tyr as a function of time.
- Published
- 2021
32. Understanding the Photothermal Response of CBNP Nanofluids Using Thermal Lens Spectroscopic Techniques
- Author
-
Subhajit Chakraborty, Amit Kumar Mishra, Ashwini Kumar Rawat, and Debabrata Goswami
- Abstract
We performed a dual beam Z-Scan experiment to examine the thermal lensing effects in CBNP nanofluids. The photothermal characteristics and heat dissipation dynamics were observed for these nanofluids at different levels of their linear absorption.
- Published
- 2021
33. Do EHR and HIE deliver on their promise? Analysis of Pennsylvania acute care hospitals
- Author
-
Dinesh R. Pai, Balaraman Rajan, and Subhajit Chakraborty
- Subjects
Economics and Econometrics ,Management Science and Operations Research ,General Business, Management and Accounting ,Industrial and Manufacturing Engineering - Published
- 2022
34. Social media hospital ratings and HCAHPS survey scores
- Author
-
Subhajit Chakraborty and E. Mitchell Church
- Subjects
Health Policy ,05 social sciences ,Hospital quality ,medicine.disease ,Hospitals ,United States ,03 medical and health sciences ,0302 clinical medicine ,Patient Satisfaction ,Health Care Surveys ,0502 economics and business ,Patient experience ,medicine ,Business, Management and Accounting (miscellaneous) ,Social media ,030212 general & internal medicine ,Patient review ,Medical emergency ,Psychology ,Healthcare providers ,Social Media ,050203 business & management - Abstract
PurposeTo empirically verify whether patient hospital satisfaction ratings on social media such as Yelp provide similar information as the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) surveys.Design/methodology/approachOLS and ordinal regressions performed on secondary data obtained from Yelp.com and 2016 Hospital Compare database disclosed by CMS.FindingsResults show that the patient hospital satisfaction ratings from Yelp can predict the patient experience of care domain scores obtained through the annual HCAHPS surveys and are also positively and significantly correlated to the overall hospital quality performance scores given by CMS.Research limitations/implicationsStudy suggests that social media patient review information could be used to supplement the information obtained from HCAHPS surveys, thereby providing hospitals more accurate information about their patient experiences.Practical implicationsHospital leaders need not wait an entire year to receive their HCHAPS scores to know about the issues related to their patient experience that need improvement and can periodically refer to free Yelp patient review scores on Yelp.com to obtain similar information.Originality/valueTo the best of knowledge, this research is the first to empirically demonstrate that patient reviews freely obtained from social media sites like Yelp can provide similar information as obtained from HCAHPS surveys and can thus be used to supplement HCAHPS.
- Published
- 2020
35. Preferential Binding of Thioflavin T to AT-Rich DNA: White Light Emission through Intramolecular Förster Resonance Energy Transfer
- Author
-
Srikrishna Pramanik, Ushasi Pramanik, Somen Nandi, Atanu Nandy, Saptarshi Mukherjee, and Subhajit Chakraborty
- Subjects
Light ,Base pair ,Chemistry ,02 engineering and technology ,DNA ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Fluorescence ,Intercalating Agents ,0104 chemical sciences ,Nucleobase ,Crystallography ,chemistry.chemical_compound ,Förster resonance energy transfer ,Intramolecular force ,Ethidium ,White light ,Fluorescence Resonance Energy Transfer ,General Materials Science ,Thioflavin ,Benzothiazoles ,Physical and Theoretical Chemistry ,0210 nano-technology - Abstract
Herein we report the effect of different nucleobase pair compositions on the association-induced fluorescence enhancement property of Thioflavin T (ThT), upon binding with 20 base pair long double-stranded DNA (dsDNA). Analysis of binding and decay constants along with the association (
- Published
- 2020
36. Entropy Analysis of MHD Variable Thermal Conductivity Fluid Flow Past a Convectively Heated Stretching Cylinder
- Author
-
Sanatan Das, Rabindra Nath Jana, Subhajit Chakraborty, and Oluwole Daniel Makinde
- Subjects
Radiation ,Materials science ,020209 energy ,02 engineering and technology ,Mechanics ,Condensed Matter Physics ,Bejan number ,Physics::Fluid Dynamics ,Entropy (classical thermodynamics) ,Thermal conductivity ,0202 electrical engineering, electronic engineering, information engineering ,Fluid dynamics ,General Materials Science ,Magnetohydrodynamics - Abstract
The present study is related to entropy analysis during magnetohydrodynamic (MHD) boundary layer flow of a viscous incompressible electrically conducting fluid past a stretching cylinder with convective heating in the presence of a transverse magnetic field. The governing boundary layer equations in cylindrical form are simplified by means of appropriate similarity transformations. Numerical solutions with high precision are obtained using Runge-Kutta fourth order scheme with eminent shooting technique. The effects of the pertinent parameters on the fluid velocity, temperature, entropy generation number, Bejan number as well as the shear stress at the surface of the cylinder are discussed graphically and quantitatively. It is examined that due to the presence of magnetic field, entropy generation can be controlled and reduced. Bejan number is plotted to present a comparative analysis of entropy generation due to heat transfer and fluid friction. It is found that Bejan number is an increasing function of Biot number.
- Published
- 2018
37. Thermal Inflection Study of Methanol-Hexane Mixtures using Time-Resolved Thermal Lens Technique
- Author
-
Debabrata Goswami, Subhajit Chakraborty, and Ashwini Kumar Rawat
- Subjects
Materials science ,Convective heat transfer ,Analytical chemistry ,law.invention ,Lens (optics) ,Hexane ,chemistry.chemical_compound ,chemistry ,law ,Thermal ,Femtosecond ,Heat transfer ,Physics::Accelerator Physics ,Methanol ,Physics::Chemical Physics ,Beam (structure) - Abstract
Time-resolved thermal lens (TL) technique is used to measure the heat transfer in pure methanol and its binary mixtures with hexane. We used dual-beam mode mismatched pump-probe scheme where a femtosecond laser beam of 1560 nm was used as a pump beam, and its frequency-doubled 780 nm beam was used as probe beam. TL Signal decreases with increasing concentration of hexane in the binary mixture. On higher concentration of Hexane in binary mixture then we have found convective heat transfer mode was absent. At 40%-60% methanol hexane mixture, we observed a sudden curious jump in TL signal.
- Published
- 2019
38. Sensing the Molecular Properties in Methanol and its Binary Mixtures using Time-Resolved Thermal Lens Spectrometer
- Author
-
Subhajit Chakraborty, Debabrata Goswami, and Ashwini Kumar Rawat
- Subjects
Materials science ,Spectrometer ,Analytical chemistry ,Nonlinear optics ,Signal ,law.invention ,Lens (optics) ,chemistry.chemical_compound ,chemistry ,law ,Heat transfer ,Thermal ,Carbon tetrachloride ,Methanol - Abstract
Mode Mismatched Pump-Probe spectroscopic method was employed to examine the thermally induced nonlinear optical properties of methanol and its binary mixtures. The heat transfer mechanism in methanol and its binary mixtures with carbon tetrachloride (CCl 4 ) at different concentrations of methanol is investigated. Methanol has the highest Thermal Lens (TL) signal, and CCl 4 does not have any TL signal at all. However, the presence of CCl 4 modulates the TL signal of the binary mixture. The time-domain shift in TL signal is observed for different concentrations of methanol, which indicates the unusual molecular behavior in the binary mixture.
- Published
- 2019
39. Enhanced Luminescent Properties of Photo-Stable Copper Nanoclusters through Formation of 'Protein-Corona'-Like Assemblies
- Author
-
Nirmal Kumar Das, Saptarshi Mukherjee, Subhajit Chakraborty, and Madhumita Mukherjee
- Subjects
Materials science ,Metal Nanoparticles ,Fluorescence correlation spectroscopy ,Protein Corona ,02 engineering and technology ,Calorimetry ,010402 general chemistry ,Photochemistry ,01 natural sciences ,Nanoclusters ,Adsorption ,Dynamic light scattering ,medicine ,Humans ,Physical and Theoretical Chemistry ,Serum Albumin ,Isothermal titration calorimetry ,021001 nanoscience & nanotechnology ,Human serum albumin ,Glutathione ,Dynamic Light Scattering ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Spectrometry, Fluorescence ,Thermodynamics ,0210 nano-technology ,Luminescence ,Copper ,Protein Binding ,medicine.drug - Abstract
In this study, interactions of synthesized copper nanoclusters (CuNCs) with a model transport protein, human serum albumin (HSA), have been systematically investigated by using various spectroscopic approaches. The interactions give rise to the formation of "protein-corona" like assemblies and the luminescence properties (both steady-state and time-resolved) are enhanced due to gradual adsorption of the protein on the surface of the NCs. The associated thermodynamics and binding parameters have been estimated resorting to luminescent experimental techniques as well as isothermal titration calorimetry (ITC) studies, indicating that every NC is surrounded by (4±1) protein molecules. The adsorption of HSA on the surface of the NCs has been characterized by dynamic light scattering (DLS) and time-resolved anisotropy measurements. Finally, fluorescence correlation spectroscopy (FCS) data substantiate the emergence of new "protein-corona" like assemblies resulting in slower translational diffusion motions and concomitant rise of the hydrodynamic diameters.
- Published
- 2018
40. Investigating healthcare brand communities: The impact of online hospital reviews
- Author
-
E. Mitchell Church and Subhajit Chakraborty
- Subjects
Marketing ,Value (ethics) ,Internet ,business.industry ,Communication ,030503 health policy & services ,05 social sciences ,Public relations ,Hospitals ,03 medical and health sciences ,Brand community ,Patient Satisfaction ,Health Care Surveys ,Outcome Assessment, Health Care ,0502 economics and business ,General Health Professions ,Health care ,Humans ,050211 marketing ,Quality of care ,0305 other medical science ,Psychology ,business ,Qualitative Research ,Quality Indicators, Health Care - Abstract
This study examines hospital brand communities to improve the understanding of what patients value and how they view the opinions and experiences of other community members. Results from the empirical analysis of brand communities of 364 hospitals involving over 22,000 patient reviews on Yelp.com show that the brand community influences patient decision making in a number of ways. While determining the usefulness of reviews, online hospital review readers consider a combination of factors like affective language, the communication, environmental conditions, and quality of care provided in the hospital, and to a lesser extent the responsiveness of the provider.
- Published
- 2018
41. An Integrated Lean Supply Chain Framework for U.S. Hospitals
- Author
-
Subhajit Chakraborty and Jorge A. Gonzalez
- Subjects
Information Systems and Management ,Supply chain management ,Supply chain ,Business ,Management Science and Operations Research ,Statistics, Probability and Uncertainty ,Industrial organization ,Management Information Systems - Published
- 2018
42. Towards a Triadic Quality Measurement Framework for U.S. Healthcare
- Author
-
Hale Kaynak and Subhajit Chakraborty
- Subjects
Service (business) ,Teamwork ,Knowledge management ,Quality management ,business.industry ,media_common.quotation_subject ,05 social sciences ,General Business, Management and Accounting ,Conceptual framework ,0502 economics and business ,Health care ,050211 marketing ,Quality (business) ,Systems thinking ,business ,Psychology ,Medicaid ,health care economics and organizations ,050203 business & management ,media_common - Abstract
Although there are various measures of healthcare quality, such as those used by the Centers for Medicare and Medicaid Services (CMS), an inclusive perspective that considers the patient, the hospital's external and internal relationships, and the nodal organizations is missing. Medical practitioner comments from the authors' interactions, coupled with the findings from their literature review, have motivated the authors to suggest that healthcare quality should be measured using a triadic approach. In this study, the authors offer an overarching conceptual framework for measuring quality in the U.S. healthcare system that utilizes a triadic approach integrating various aspects of quality at three different levels of measurement. At the micro-level, the focus is on patients–admitted and treated–and their perceptions of a hospital's service as well as outcomes. The authors suggest measures related to the healthcare teamwork quality at the meso-level. At the macro- level, in which the organization i...
- Published
- 2018
43. Unraveling molecular interactions in binary liquid mixtures with time-resolved thermal-lens-spectroscopy
- Author
-
Amit Kumar Mishra, Debabrata Goswami, Subhajit Chakraborty, and Ashwini Kumar Rawat
- Subjects
Convection ,Materials science ,Convective heat transfer ,Intermolecular force ,Analytical chemistry ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Thermal conduction ,01 natural sciences ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,chemistry.chemical_compound ,chemistry ,Heat transfer ,Volume fraction ,Materials Chemistry ,Methanol ,Physical and Theoretical Chemistry ,0210 nano-technology ,Spectroscopy - Abstract
Non-contact localized laser heating-based thermal lensing has emerged as a technique for probing the heat transport in liquids. A mode-mismatched dual-beam pump–probe spectroscopic technique was employed to investigate the photothermal response and modes of heat dissipation in methanol and binary mixtures of methanol with polar (water, methanol (MeOH)) and nonpolar (CCl4) solvents. We recorded the time-resolved thermal lens (TL) signal of a probe beam at 780 nm after heat deposition by a 1560 nm pump beam. For pure solvents, the TL signal was found to be approximately one order of magnitude larger for methanol than for water, DMSO, or CCl4, implying that the energy deposition is larger for methanol than for any of the other solvents. Subsequently, binary mixtures were studied where the TL signal increased with an increase in the volume fraction of methanol. All TL signals are shown to have a physical interpretation in terms of heat conduction and convection. In the case of methanol–water, the observed trend can be rationalized in terms of a strong intermolecular interaction. Convective heat transfer is shown to dominate the overall heat transfer in pure methanol and in binary mixtures for all volume fractions where MeOH is in excess of 50%. No convection is observed for very dilute mixtures with a small amount of methanol; in this case, heat conduction is sufficient to reach equilibration. Interestingly, for binary mixtures of methanol with DMSO or water, a decreasing trend is observed in the concentration range between 90% and 100% volume fraction of methanol. We observe also that the TL signal is modified in case of intermolecular interactions forming large clusters of methanol with the cosolvent. In such cases, heat diffusion is affected. Thus, TL can be seen as a sensitive probe for intermolecular interactions as well.
- Published
- 2021
44. Improving Hospital Efficiency While Angering Patients?
- Author
-
Earnie M. Church and Subhajit Chakraborty
- Subjects
General Medicine - Published
- 2021
45. Time Evolution of Local pH Around a Photo-Acid in Water and a Polymer Hydrogel: Time Resolved Fluorescence Spectroscopy of Pyranine
- Author
-
Somen Nandi, Saptarshi Mukherjee, Kankan Bhattacharyya, and Subhajit Chakraborty
- Subjects
Materials science ,Analytical chemistry ,Fluorescence correlation spectroscopy ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Micelle ,Atomic and Molecular Physics, and Optics ,0104 chemical sciences ,Pyranine ,chemistry.chemical_compound ,chemistry ,Excited state ,Emission spectrum ,Physical and Theoretical Chemistry ,Time-resolved spectroscopy ,0210 nano-technology ,Spectroscopy ,Fluorescence anisotropy - Abstract
In this work, we propose a new analysis of the time resolved emission spectra of a photo-acid, HA, pyranine (8-hydroxypyrene-1,3,6-trisulphonic acid, HPTS) based on time resolved area normalized emission spectra (TRANES). Presence of an isoemissive point in TRANES confirms the presence of two emissive species (HA and A- ) inside the system in bulk water and inside a co-polymer hydrogel [F127, (PEO)100 -(PPO)70 -(PEO)100 ]. We show that following electronic excitation, the local pH around HPTS, is much lower than the bulk pH presumably because of ejection of proton from the photo-acid in the excited state. With increase in time, the local pH increases and reaches the bulk value. We further, demonstrate that the excited state pKa of HPTS may be estimated from the emission intensities of HA and A- at long time. The time constant for time evolution of pH is ∼630 ps in water, ∼1300 ps in F127 gel and ∼4700 ps in CTAB micelle. The location and local viscosity sensed by the probe is ascertained using fluorescence correlation spectroscopy (FCS) and fluorescence anisotropy decay. The different values of the local viscosity reported by these two methods are reconciled.
- Published
- 2019
46. Structure, Activity, and Dynamics of Human Serum Albumin in a Crowded Pluronic F127 Hydrogel
- Author
-
Kankan Bhattacharyya, Saptarshi Mukherjee, Atanu Nandy, Somen Nandi, and Subhajit Chakraborty
- Subjects
Circular dichroism ,Serum albumin ,Fluorescence correlation spectroscopy ,Serum Albumin, Human ,Poloxamer ,Buffers ,010402 general chemistry ,01 natural sciences ,Fluorescence spectroscopy ,chemistry.chemical_compound ,0103 physical sciences ,Materials Chemistry ,medicine ,Humans ,Physical and Theoretical Chemistry ,010304 chemical physics ,biology ,Chemistry ,Relaxation (NMR) ,Hydrogels ,Buffer solution ,Human serum albumin ,Fluorescence ,0104 chemical sciences ,Surfaces, Coatings and Films ,embryonic structures ,Biophysics ,biology.protein ,medicine.drug - Abstract
Structure, activity, and dynamics of a plasma protein, human serum albumin (HSA), inside a crowded environment of F127 gel are studied by circular dichroism (CD), fluorescence correlation spectroscopy (FCS), and picosecond time-resolved fluorescence spectroscopy. For this purpose, the protein is covalently labeled by a maleimide dye, 7-(diethylamino)-3-(4-maleimidylphenyl)-4-methyl-coumarin (CPM). The circular dichroism (CD) spectra suggest that the protein is more structured in the gel reflecting about the biological activities of the protein. FCS results demonstrate that compared to that in bulk water (buffer solution), translational diffusion is about 59 times slower inside the F127 gel. This indicates higher translational friction (viscosity) sensed by the probe (CPM). On the contrary, rotational relaxation (and hence, rotational friction) is more or less similar in F127 gel and in bulk water. FCS results further indicate that the time scales of conformational relaxation of the protein are substantially slow inside the crowded environment of F127 gel. The fast component of conformational relaxation is retarded by ∼55 times, and the slow component by ∼20 times. Fluorescence maximum of CPM bound to HSA show a ∼5 nm red shift, implying that the microenvironment of the probe, CPM, is more polar inside the gel. Solvation dynamics of CPM-labeled HSA inside the gel (⟨τs⟩ ∼ 300 ps) is faster compared to that for the protein in bulk water (⟨τs⟩ ∼ 600 ps).
- Published
- 2019
47. Bridging hospital quality leadership to patient care quality
- Author
-
Subhajit Chakraborty, José A. Pagán, and Hale Kaynak
- Subjects
Economics and Econometrics ,Teamwork ,021103 operations research ,Quality management ,Isolation (health care) ,business.industry ,media_common.quotation_subject ,05 social sciences ,0211 other engineering and technologies ,Team effectiveness ,02 engineering and technology ,Management Science and Operations Research ,General Business, Management and Accounting ,Industrial and Manufacturing Engineering ,InformationSystems_GENERAL ,Empirical research ,Nursing ,0502 economics and business ,Health care ,Technology integration ,Quality (business) ,business ,Psychology ,050203 business & management ,media_common - Abstract
Understanding what drives quality in the delivery of healthcare services is critical to improve the patient care experience. In a hospital, the integration of technology platforms and effective teamwork promote quality care, but this outcome requires that hospital leadership prioritizes technology integration and commits resources to sustain effective healthcare delivery teams. Some of these concepts have been investigated with a limited focus or in very narrow research contexts. Because these concepts do not interact in isolation, an empirical study that examines the relationships between them simultaneously is important to explore the links between hospital quality leadership (QL), technology integration (TI), healthcare team effectiveness (HTE) and patient care quality (PCQ). An online survey of 300 middle and senior-level U.S. hospital executives and quality heads completed during a four-month period is used to test the research hypotheses drawn primarily from quality management, information processing, and team effectiveness theories. The results suggest that hospital leaders should emphasize the integration of all technology systems in their hospitals and continuously encourage their healthcare teams to work effectively thereby improving the quality of patient care delivered. Based on the post-hoc results, we suggest that hospital quality leaders should recognize the difference in magnitude of the effects of HTE and TI on the four PCQ facets.
- Published
- 2021
48. An intrinsically disordered protein in F127 hydrogel: Fluorescence correlation spectroscopy and structural diversity of beta casein
- Author
-
Saptarshi Mukherjee, Subhajit Chakraborty, Ushasi Pramanik, and Kankan Bhattacharyya
- Subjects
Chemistry ,Tryptophan ,General Physics and Astronomy ,Fluorescence correlation spectroscopy ,02 engineering and technology ,Radius ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Intrinsically disordered proteins ,01 natural sciences ,Fluorescence ,0104 chemical sciences ,law.invention ,law ,Casein ,Biophysics ,Copolymer ,Physical and Theoretical Chemistry ,Crystallization ,0210 nano-technology - Abstract
Intrinsically Disordered Proteins (IDPs) switch between diverse structures which prevents them from crystallization. FCS of the IDP beta casein (β-CN), labeled with Alexa488, suggests that in buffer the structure fluctuates between a highly extended state (radius 34.5 ± 7 nm) and a highly collapsed state (radius 1 nm). To understand their behavior in a highly crowded environment, like the cell, β-CN was studied inside a pluronic copolymer (F127) where a 2-times higher rotational and 10–16 times higher translational friction were observed. Fluorescence emissions of Tryptophan indicate that the protein is localized at corona region exposing to the void region of the gel.
- Published
- 2021
49. Cultural and Institutional Differences in Healthcare Quality Across Three North-American Nations
- Author
-
Jorge A. Gonzalez, Cara-Lynn Scheuer, Miguel Sahagun, and Subhajit Chakraborty
- Subjects
Health services ,business.industry ,media_common.quotation_subject ,Health care ,Quality (business) ,General Medicine ,Sociology ,Meaning (existential) ,Public relations ,business ,Healthcare providers ,media_common - Abstract
The meaning of health service quality differs across cultural and institutional contexts. This poses a problem for different stakeholders—patients, healthcare providers, and hospital leaders—when i...
- Published
- 2020
50. Specific ion effects on F127 hydrogel: FCS, anisotropy and solvation dynamics
- Author
-
Somen Nandi, Laxmikanta Khamari, Kankan Bhattacharyya, Saptarshi Mukherjee, and Subhajit Chakraborty
- Subjects
Solvation ,General Physics and Astronomy ,Fluorescence correlation spectroscopy ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,Chloride ,0104 chemical sciences ,Ion ,Perchlorate ,chemistry.chemical_compound ,Viscosity ,chemistry ,Picosecond ,medicine ,Physical and Theoretical Chemistry ,0210 nano-technology ,Anisotropy ,medicine.drug - Abstract
Specific interaction of the chloride and perchlorate ions with F127 hydrogel is studied by fluorescence correlation spectroscopy and picoseconds dynamics. An anionic dye C343 probes the hydrophilic corona while the hydrophobic dye C153 reports on the core. In the absence of salts, C343 experiences a translational viscosity of ~16 cP, which increases to ~29 cP in 1 M LiCl and ~39 cP in 1 M LiClO4. Anisotropy decays remain unaffected by salts. The perchlorate ion makes solvation dynamics at corona faster while the chloride ion has no effect. At core, the ions do not affect translational viscosity or solvation dynamics.
- Published
- 2019
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.