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141 results on '"Subhadeep Roy"'

1. Exploring the interaction between extracellular matrix components in a 3D organoid disease model to replicate the pathophysiology of breast cancer

Author: Anamitra Bhattacharya, Kamare Alam, Nakka Sharmila Roy, Kulwinder Kaur, Santanu Kaity, Velayutham Ravichandiran, and Subhadeep Roy
Subjects: 3D organoid, In-vitro disease model, Cell patterning, Tumor microenvironment, Extra cellular matrix, Cancer associated fibroblast, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Abstract In vitro models are necessary to study the pathophysiology of the disease and the development of effective, tailored treatment methods owing to the complexity and heterogeneity of breast cancer and the large population affected by it. The cellular connections and tumor microenvironments observed in vivo are often not recapitulated in conventional two-dimensional (2D) cell cultures. Therefore, developing 3D in vitro models that mimic the complex architecture and physiological circumstances of breast tumors is crucial for advancing our understanding of the illness. A 3D scaffold-free in vitro disease model mimics breast cancer pathophysiology by allowing cells to self-assemble/pattern into 3D structures, in contrast with other 3D models that rely on artificial scaffolds. It is possible that this model, whether applied to breast tumors using patient-derived primary cells (fibroblasts, endothelial cells, and cancer cells), can accurately replicate the observed heterogeneity. The complicated interactions between different cell types are modelled by integrating critical components of the tumor microenvironment, such as the extracellular matrix, vascular endothelial cells, and tumor growth factors. Tissue interactions, immune cell infiltration, and the effects of the milieu on drug resistance can be studied using this scaffold-free 3D model. The scaffold-free 3D in vitro disease model for mimicking tumor pathophysiology in breast cancer is a useful tool for studying the molecular basis of the disease, identifying new therapeutic targets, and evaluating treatment modalities. It provides a more physiologically appropriate high-throughput platform for screening large compound library in a 96–384 well format. We critically discussed the rapid development of personalized treatment strategies and accelerated drug screening platforms to close the gap between traditional 2D cell culture and in vivo investigations. Graphical Abstract
Published: 2023
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2. Disease spectrum and its molecular characterisation in the lentil production system of lower-Indo Gangetic plains

Author: Huma Nazneen, Raju Das, Arpita Das, Subrata Dutta, Sudip Bhattacharya, Subhas Patar, Subhadeep Roy, Sanjeev Gupta, and Shiv Kumar
Subjects: lentil, collar rot, blight complex, rust, molecular characterization, Geospatial mapping, Plant culture, SB1-1110
Abstract: Lentil is a food legume grown in the Indo-Gangetic plains including lower Gangetic Bengal (LGB). Lentil productivity in this zone is severely impeded because of the prevalence of several biotic cues. Plausible reports regarding the status of disease scenario and the associated risk factors are missing. Therefore, judicious crop management strategies are lacking. An intensive survey of 267 farmers’ fields was conducted over 3 years in major lentil-growing districts of LGB to evaluate the disease incidence and prevalence. Additional insights were generated, apprehending isolation and characterisation of associated pathogens through spore morphology and molecular markers as well as elucidating the role of biophysical factors in influencing disease development. Climate change has shifted the disease dimension of lentil and precipitated new disease complexes of great risk, which was reflected through geospatial mapping results in the present study. The prevalence of three major diseases, namely collar rot (Sclerotium rolfsii), lentil blight complex (LBC) incited by both Alternaria and Stemphylium, and lentil rust (Uromyces viciae-fabae), was ascertained through cultural and molecular studies and contextualised through pathogenicity appraisal. This study is the first to investigate the complex mixed infection of Alternaria alternata and Stemphylium botryosum, successfully isolating S. botyrosum in India, and confirming the pathogens through sequencing by using internal transcribed spacer (ITS) primers and Stemphylium-specific Glycerol-3-phosphate dehydrogenase 1 (gpd1) and gpd2 primers. Unlike late planting, early planting promoted collar rot infestation. LBC and rust incidence were magnified in late planting. Soil texture resulted in the spatial distribution of collar rot disease. The surveyed data also highlighted the potential role of resistant cultivars and cropping pattern intervention to ensure associational resistance towards addressing the disease bottleneck in lentil.
Published: 2024
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3. Role of Angiogenesis and Its Biomarkers in Development of Targeted Tumor Therapies

Author: Anchal Pathak, Ajay Kumar Pal, Subhadeep Roy, Mukesh Nandave, and Keerti Jain
Subjects: Internal medicine, RC31-1245
Abstract: Angiogenesis plays a significant role in the human body, from wound healing to tumor progression. “Angiogenic switch” indicates a time-restricted event where the imbalance between pro- and antiangiogenic factors results in the transition from prevascular hyperplasia to outgrowing vascularized tumor, which eventually leads to the malignant cancer progression. In the last decade, molecular players, i.e., angiogenic biomarkers and underlying molecular pathways involved in tumorigenesis, have been intensely investigated. Disrupting the initiation and halting the progression of angiogenesis by targeting these biomarkers and molecular pathways has been considered as a potential treatment approach for tumor angiogenesis. This review discusses the currently known biomarkers and available antiangiogenic therapies in cancer, i.e., monoclonal antibodies, aptamers, small molecular inhibitors, miRNAs, siRNAs, angiostatin, endostatin, and melatonin analogues, either approved by the U.S. Food and Drug Administration or currently under clinical and preclinical investigations.
Published: 2024
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4. Editorial: Pharmaceutically targeting hypoxia in the breast cancer microenvironment: mechanistic and translational approaches

Author: Manjari Singh, Manash K. Paul, and Subhadeep Roy
Subjects: breast cancer, hypoxia, drug delivery, tumor microenvironment (TME), HIF-1α, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2023
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5. A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis

Author: Maurizio Chioccioli, Subhadeep Roy, Rachel Newell, Linda Pestano, Brent Dickinson, Kevin Rigby, Jose Herazo-Maya, Gisli Jenkins, Steward Ian, Gauri Saini, Simon R. Johnson, Rebecca Braybrooke, Guying Yu, Maor Sauler, Farida Ahangari, Shuizi Ding, Joseph DeIuliis, Nachelle Aurelien, Rusty L. Montgomery, and Naftali Kaminski
Subjects: Idiopathic pulmonary fibrosis, MicroRNA, miR-29, RNA therapies, Medicine, Medicine (General), R5-920
Abstract: Summary: Background: MicroRNAs are non-coding RNAs that negatively regulate gene networks. Previously, we reported that systemically delivered miR-29 mimic MRG-201 reduced fibrosis in animal models, supporting the consideration of miR-29-based therapies for idiopathic pulmonary fibrosis (IPF). Methods: We generated MRG-229, a next-generation miR-29 mimic based on MRG-201 with improved chemical stability due to additional sugar modifications and conjugation with the internalization moiety BiPPB (PDGFbetaR-specific bicyclic peptide)1. We investigated the anti-fibrotic efficacy of MRG-229 on TGF-β1 treated human lung fibroblasts (NHLFs), human precision cut lung slices (hPCLS), and in vivo bleomycin studies; toxicology was assessed in two animal models, rats, and non-human primates. Finally, we examined miR-29b levels in a cohort of 46 and 213 patients with IPF diagnosis recruited from Yale and Nottingham Universities (Profile Cohort), respectively. Findings: The peptide-conjugated MRG-229 mimic decreased expression of pro-fibrotic genes and reduced collagen production in each model. In bleomycin-treated mice, the peptide-conjugated MRG-229 mimic downregulated profibrotic gene programs at doses more than ten-fold lower than the original compound. In rats and non-human primates, the peptide-conjugated MRG-229 mimic was well tolerated at clinically relevant doses with no adverse findings observed. In human peripheral blood from IPF patients decreased miR-29 concentrations were associated with increased mortality in two cohorts potentially identified as a target population for treatment. Interpretation: Collectively, our results provide support for the development of the peptide-conjugated MRG-229 mimic as a potential therapy in humans with IPF. Funding: This work was supported by NIH NHLBI grants UH3HL123886, R01HL127349, R01HL141852, U01HL145567.
Published: 2022
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6. Correlation Between Avalanches and Emitted Energies During Fracture With a Variable Stress Release Range

Author: Narendra K. Bodaballa, Soumyajyoti Biswas, and Subhadeep Roy
Subjects: disordered systems, stress release range, fiber bundle model, avalanche statistics, acoustic emission, correlation function, Physics, QC1-999
Abstract: We observe the failure process of a fiber bundle model with a variable stress release range, γ, and higher the value of γ, lower the stress release range. By tuning γ from low to high, it is possible to go from the mean-field (MF) limit of the model to the local load-sharing (LLS) limit where local stress concentration plays a crucial role. In the MF limit, individual avalanches (number of fibers breaking in going from one stable state to the next, s) and the corresponding energies E emitted during those avalanches have one-to-one linear correlation. This results in the same size distributions for both avalanches (P(s)) and energy bursts (Q(E)): a scale-free distribution with a universal exponent value of −5/2. With increasing γ, the model enters the LLS limit beyond some γc. In this limit, due to the presence of local stress concentrations around a damaged region, such correlation C(γ) between s and E decreases, i.e., a smaller avalanche can emit a large amount of energy or a large avalanche may emit a small amount of energy. The nature of the decrease in the correlation between s and E depends highly on the dimension of the bundle. In this work, we study the decrease in the correlation between avalanche size and the corresponding energy bursts with an increase in the load redistribution localization in the fiber bundle model in one and two dimensions. Additionally, we note that the energy size distribution remains scale-free for all values of γ, whereas the avalanche size distribution becomes exponential for γ > γc.
Published: 2022
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7. Formulation and Intracellular Trafficking of Lipid–Drug Conjugate Nanoparticles Containing a Hydrophilic Antitubercular Drug for Improved Intracellular Delivery to Human Macrophages

Author: Sayantan Pandit, Subhadeep Roy, Jonathan Pillai, and Subham Banerjee
Subjects: Chemistry, QD1-999
Published: 2020
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8. From Nucleation to Percolation: The Effect of System Size when Disorder and Stress Localization Compete

Author: Subhadeep Roy
Subjects: disordered systems, fiber bundle model, stress release range, nucleation and growth, percolation, spatial correlation, Physics, QC1-999
Abstract: A phase diagram for a one-dimensional fiber bundle model is constructed with a continuous variation in two parameters guiding the dynamics of the model: strength of disorder and range of stress relaxation. When the range of stress relaxation is very low, the stress concentration plays a prominent role and the failure process is nucleating where a single crack propagates from a particular nucleus with a very high spatial correlation unless the disorder strength is high. On the other hand, a high range of stress relaxation represents the mean-field limit of the model where the failure events are random in space. At an intermediate disorder strength and stress release range, when these two parameters compete, the failure process shows avalanches and precursor activities. As the size of the bundle is increased, it favors a nucleating failure. In the thermodynamic limit, we only observe a nucleating failure unless either the disorder strength is extremely high or the stress release range is high enough so that the model is in the mean-field limit. A complex phase diagram on the plane of disorder strength, stress release range, and system size is presented showing different failure modes - 1) nucleation 2) avalanche, and 3) percolation, depending on the spatial correlation observed during the failure process.
Published: 2021
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9. Repurposing Combination Therapy of Voacamine With Vincristine for Downregulation of Hypoxia-Inducible Factor-1α/Fatty Acid Synthase Co-axis and Prolyl Hydroxylase-2 Activation in ER+ Mammary Neoplasia

Author: Lakhveer Singh, Subhadeep Roy, Anurag Kumar, Shubham Rastogi, Dinesh Kumar, Mohd. Nazam Ansari, Abdulaziz S. Saeedan, Manjari Singh, and Gaurav Kaithwas
Subjects: mammary gland carcinoma, hypoxia inducible factor-1α (HIF-1α), fatty acid synthase (FASN), prolyl hydroxylase-2, voacamine, repurposable drugs, Biology (General), QH301-705.5
Abstract: The current study investigated the role of combination therapy with voacamine and vincristine in preventing mammary gland carcinoma through prolyl hydroxylase-2 activation. Prolyl hydroxylase-2 activation leads to the downregulation of hypoxia-inducible factor-1α and fatty acid synthase. Overexpression of hypoxia-inducible factor-1α and fatty acid synthase has been previously reported in solid tumors of the mammary gland. After screening a battery of natural compounds similar to vincristine, voacamine was selected as a possible prolyl hydroxylase-2 activator, and its activity was evaluated using a 7,12-dimethylbenz[a]anthracene-induced rat model. The combination therapy was evaluated for cardiac toxicity using a hemodynamic profile. Angiogenic markers were evaluated by carmine staining. Monotherapy and combination therapy were also evaluated for liver and kidney toxicity using hematoxylin and eosin staining. The antioxidant potential was delineated using oxidative stress markers. The serum metabolomic profile was studied using NMR spectroscopy, and the disruption of fatty acids was evaluated using gas chromatography. Western blotting of proteins involved in hypoxic pathways was performed to decipher the action of therapy at the molecular level. Immunoblotting analysis validated that combination therapy has potential toss with prolyl hydroxylase-2 activity and thus initiates proteolytic degradation of hypoxia-inducible factor-1α and its consequent effects. Combination therapy also stimulated programmed cell death (apoptosis) in rapidly dividing cancer cells. The present study explored the role of voacamine inactivation of prolyl hydroxylase-2, which can decrease the overexpression of hypoxia-inducible factor-1α and fatty acid synthase in mammary gland carcinoma cells.
Published: 2021
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10. Correction: Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling

Author: Manjari Singh, Sweta Kasna, Subhadeep Roy, Sara Aldosary, Abdulaziz S. Saeedan, Mohd. Nazam Ansari, and Gaurav Kaithwas
Subjects: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2022
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11. Role of Pore-Size Distribution on Effective Rheology of Two-Phase Flow in Porous Media

Author: Subhadeep Roy, Santanu Sinha, and Alex Hansen
Subjects: non-linear fluid flow, two-phase flow, porous media, pore-size distribution, effective rheology, Environmental technology. Sanitary engineering, TD1-1066
Abstract: Immiscible two-phase flow of Newtonian fluids in porous media exhibits a power law relationship between flow rate and pressure drop when the pressure drop is such that the viscous forces compete with the capillary forces. When the pressure drop is large enough for the viscous forces to dominate, there is a crossover to a linear relation between flow rate and pressure drop. Different values for the exponent relating the flow rate and pressure drop in the regime where the two forces compete have been reported in different experimental and numerical studies. We investigate the power law and its exponent in immiscible steady-state two-phase flow for different pore size distributions. We measure the values of the exponent and the crossover pressure drop for different fluid saturations while changing the shape and the span of the distribution. We consider two approaches, analytical calculations using a capillary bundle model and numerical simulations using dynamic pore-network modeling. In case of the capillary bundle when the pores do not interact to each other, we find that the exponent is always equal to 3/2 irrespective of the distribution type. For the dynamical pore network model on the other hand, the exponent varies continuously within a range when changing the shape of the distribution whereas the width of the distribution controls the crossover point.
Published: 2021
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12. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling

Author: Manjari Singh, Sweta Kasna, Subhadeep Roy, Sara Aldosary, Abdulaziz S. Saeedan, Mohd. Nazam Ansari, and Gaurav Kaithwas
Subjects: Tadalafil, ER+ mammary gland cancer, Mitochondrial stress, PDE-5 inhibitor, N-methyl-n-nitrosourea, DuCLOX, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Abstract Background This study evaluates the anti-cancer effects of Tadalafil (potent PDE-5 inhibitor) in female albino wistar rats against n-methyl n-nitrosourea induced mammary gland carcinogenesis. Methods The animals were selected and randomly divided among four groups and each group contains six animals per group. The animal tissue and serum samples were evaluated for the presence of antioxidant parameters and the cellular morphology was studied using carminic staining, haematoxylin staining and scanning electron microscopy followed by immunoblotting analysis. Results On the grounds of hemodynamic recordings and morphology, n-methyl n-nitrosourea treated group showed distorted changes along with distorted morphological parameters. For morphological analysis, the mammary gland tissues were evaluated using scanning electron microscopy, whole mount carmine staining, haematoxylin and eosin staining. The serum samples were evaluated for the evaluation of oxidative stress markers and inflammatory markers. The level of caspase 3 and 8 were also evaluated for the estimation of apoptosis. The fatty acid profiling of mammary gland tissue was evaluated using fatty acid methyl esters formation. The mitochondrial mediated apoptosis and inflammatory markers were evaluated using immunoblotting assay. Conclusion The results confirm that Tadalafil treatment restored all the biological markers to the normal and its involvement in mitochondrial mediated death apoptosis pathway along with inhibition of inflammatory markers.
Published: 2019
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13. Model for creep failure with healing

Author: Subhadeep Roy and Takahiro Hatano
Subjects: Physics, QC1-999
Abstract: To understand general properties of creep failure with healing effects, we study a mean-field fiber bundle model with probabilistic rupture and rejoining processes. The dynamics of the model is determined by two factors: bond breaking and formation of new bonds. Steady states are realized due to the balance between breaking and healing beyond a critical healing factor, below which the bundle breaks completely. Correlation between the fluctuating value of strain generated in the model with time at the steady state leads to a characteristic time that diverges in a scale-free manner as we approach the critical healing factor. Transient behaviors in the strain rate also involve a power law with a nonuniversal exponent.
Published: 2022
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14. Size Distribution of Emitted Energies in Local Load Sharing Fiber Bundles

Author: Subhadeep Roy and Soumyajyoti Biswas
Subjects: fiber bundle model, local load sharing, energy emission, threshold activated dynamics, avalanches, Physics, QC1-999
Abstract: We study the local load sharing fiber bundle model and its energy burst statistics. While it is known that the avalanche size distribution of the model is exponential, we numerically show here that the avalanche size (s) and the corresponding average energy burst (〈E〉) in this version of the model have a non-linear relation (〈E〉 ~ sγ). Numerical results indicate that γ ≈ 2.5 universally for different failure threshold distributions. With this numerical observation, it is then possible to show that the energy burst distribution is a power law, with a universal exponent value of −(γ + 1).
Published: 2021
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15. Flow-Area Relations in Immiscible Two-Phase Flow in Porous Media

Author: Subhadeep Roy, Santanu Sinha, and Alex Hansen
Subjects: porous media, thermodynamic relations, seepage velocity, steady state flow, two phase flow, Physics, QC1-999
Abstract: We present a theoretical framework for immiscible incompressible two-phase flow in homogeneous porous media that connects the distribution of local fluid velocities to the average seepage velocities. By dividing the pore area along a cut transversal to the average flow direction up into differential areas associated with the local flow velocities, we construct a distribution function that allows us to not only re-establish existing relationships of between the seepage velocities of the immiscible fluids, but also to find new relations between their higher moments. We support and demonstrate the formalism through numerical simulations using a dynamic pore-network model for immiscible two-phase flow with two- and three-dimensional pore networks. Our numerical results are in agreement with the theoretical considerations.
Published: 2020
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16. Caesarean section rate and postnatal bed occupancy: a retrospective study replacing assumptions with evidence

Author: Subhadeep Roy and L Montgomery Irvine
Subjects: Caesarean section, Postnatal bed occupancy, Post-caesarean length of stay, Caesarean on request, Patient choice, Public aspects of medicine, RA1-1270
Abstract: Abstract Background Obstetric units across the UK face resource pressures alongside a rising rate of Caesarean section (CS). It is assumed that this places a further burden in the form of postnatal bed demands. The number of inpatient beds has fallen nationally, and this may be used to justify attempts to restrict the CS rate. We set out to replace such assumptions with evidence. We did not find any similar contemporary analysis in a literature search. Methods The postnatal length of stay (LOS) of women delivering at Watford General Hospital, a large unit hosting around 5500 deliveries per annum, was stratified by mode of delivery. Differences within and across time periods were analysed. Results The CS rate rose from 14.5% in 1995 to 30.9% in 2015. The mean LOS post-CS declined from 4.2 to 2.4 days. These data were statistically significant to p
Published: 2018
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17. Revisiting the systemic lipopolysaccharide mediated neuroinflammation: Appraising the effect of l-cysteine mediated hydrogen sulphide on it

Author: Abdulaziz S. Al-Saeedan, Varsha Gautam, Mohd Nazam Ansari, Manjari Singh, Rajnish K. Yadav, Jitendra K. Rawat, Uma Devi, Swetlana Gautam, Subhadeep Roy, and Gaurav Kaithwas
Subjects: Therapeutics. Pharmacology, RM1-950
Abstract: The present research was ventured to examine the effect of l-cysteine on neuro-inflammation persuaded by peripheral lipopolysaccharides (LPS, 125 μg/kg, i.p.) administration. No behavioral, biochemical, and inflammatory abnormality was perceived in the brain tissues of experimental animals after LPS administration. l-cysteine precipitated marginal symptoms of toxicity in the brain tissue. Similar pattern of wholesome effect of LPS were perceived when evaluated through the brain tissue fatty acid profile, histopathologically and NF-ĸBP65 protein expression. LPS was unsuccessful to alter the levels of hydrogen sulphide (H2S), cyclooxygenase (COX) and lipoxygenase (LOX) enzyme in brain tissue. LPS afforded significant peripheral toxicity, when figured out through inflammatory markers (COX, LOX), gaseous signaling molecules nitric oxide (NO), H2S, liver toxicity (SGOT, SGPT), and inflammatory transcription factor (NF-ĸBP65) and l-cysteine also provided a momentous protection against the same as well. The study inculcated two major finding, firstly LPS (i.p.) cannot impart inflammatory changes to brain and secondly, l-cysteine can afford peripheral protection against deleterious effect of LPS (i.p.) Keywords: Hydrogen sulphide, l-cysteine, Inflammation, Lipopolysaccharide, Neuroinflammation
Published: 2018
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18. Molecular docking analysis and antidiabetic activity of Rifabutin against STZ-NA induced diabetes in albino wistar rats

Author: Danish Ahmed, Mohd. Ibrahim Khan, Gaurav Kaithwas, Subhadeep Roy, Swetlana Gautam, Manjari Singh, Uma Devi, Rajnish Yadav, Jitendra Rawat, and Shubhini Saraf
Subjects: Blood glucose, CADD, GLP-1R, Rifabutin, STZ-NA, Medicine (General), R5-920, Science
Abstract: Computer Aided Drug Design (CADD) molecular docking program used in this study and as a result Rifabutin was retrieved as structurally similar drug molecule to Lixisenatide (A widely used GLP-1 agonist). To afford beneficial reason in vitro study conducted which too provides a favourable mark for prospective inhibition of α-glucosidase and α-amylase enzyme and thereby evaluated for its antidiabetic potential against Streptozotocin (STZ) and Nicotinamide (NA) induced diabetes in albino wistar rats. Rifabutin demonstrated significant efficacy towards restoring the blood glucose, insulin and distorted lipid profile in the animals treated with STZ-NA. Rifabutin also regulated the inflammatory (Nitric Oxide) and oxidative stress (TBARs, SOD, Catalase, GSH and protein carbonyl) markers in the pancreatic tissue of the STZ-NA treated animals. When scrutinized on the grounds electrocardiographic and heart rate variability (HRV) changes, Rifabutin decreased the heart rate, without much affecting the QRS, QT and QTc interval. Rifabutin was also evident to be less hepatotoxic in comparison to the standard metformin, providing an added advantage as an anti-diabetic agent. The study concluded that the low dose of rifabutin can favourably regulate of the blood glucose and other biochemical paradigms in comparison to high dose of rifabutin.
Published: 2017
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19. Effective Rheology of Two-Phase Flow in a Capillary Fiber Bundle Model

Author: Subhadeep Roy, Alex Hansen, and Santanu Sinha
Subjects: two-phase flow, capillary fiber bundle model, effective rheology, non-Darcy flow at low velocity, porous media, Physics, QC1-999
Abstract: We investigate the effective rheology of two-phase flow in a bundle of parallel capillary tubes carrying two immiscible fluids under an external pressure drop. The diameter of the tubes vary along the length which introduce capillary threshold pressures. We demonstrate through analytical calculations that a transition from a linear Darcy to a non-linear behavior occurs while decreasing the pressure drop ΔP, where the total flow rate 〈Q〉 varies with ΔP with an exponent 2 as 〈Q〉~ΔP2 for uniform threshold distribution. The exponent changes when a lower cut-off Pm is introduced in the threshold distribution and in the limit where ΔP approaches Pm, the flow rate scales as 〈Q〉 ~ (|ΔP|-Pm)3/2. While considering threshold distribution with a power α, we find that the exponent γ for the non-linear regime vary as γ = α + 1 for Pm = 0 and γ = α + 1/2 for Pm > 0. We provide numerical results in support of our analytical findings.
Published: 2019
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20. Transcutaneous Vagus Nerve Stimulation Regulates the Cholinergic Anti-inflammatory Pathway to Counteract 1, 2-Dimethylhydrazine Induced Colon Carcinogenesis in Albino wistar Rats

Author: Jitendra K. Rawat, Subhadeep Roy, Manjari Singh, Swetlana Guatam, Rajnish K. Yadav, Mohd Nazam Ansari, Sara A. Aldossary, Abdulaziz S. Saeedan, and Gaurav Kaithwas
Subjects: transcutaneous auricular vagus nerve stimulation, cholinergic anti-inflammatory pathway, colon cancer, acetylcholine, 2-dimethyl hydrazine, Therapeutics. Pharmacology, RM1-950
Abstract: The present work was undertaken to study the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on 1, 2-dimethyhydrazine (DMH) induced colon cancer and role of the cholinergic anti-inflammatory pathways (CAP) in the same. Groups of rats were randomly divided into ten groups (n = 8). DMH administration was very well apparent for autonomic dysfunction as observed through distorted hemodynamic (electrocardiogram and heart rate variability), increased aberrant crypt foci and flat neoplastic lesions (methylene blue staining, scanning electron microscopy and Hematoxylin and eosin staining). DMH administration was also recorded for per-oxidative damage. taVNS application restored the autonomic function, cellular morphology and curtailed the oxidative damage. DMH application conspicuously inhibited the mitochondrial apoptosis which was restored back after taVNS application, when scrutinized through immunoblotting and quantitative real time polymerase chain reaction studies. taVNS application up-regulated the CAP as perceived through increased expression for α7 nicotinic acetylcholine receptor(α7nAchR) and decreased expression for nuclear factor kappa-ligand-chain-enhancer of activated B cells (NFκBp65), tissue necrosis factor-α and high mobility group box-1 at protein and mRNA levels. All in all, taVNS up-surged the CAP to counteract DMH induced colon carcinogenesis. Among all the stimulation parameters used, taVNS 3 (pulse width-1 ms, frequency-6 Hz, voltage-6 v, duration-240 min) was observed to be the most effective. Since only chemotherapy and surgery are available options for management of CRC, which are troublesome and painful, there is currently no non-invasive method available for management of CRC. Results of the current study affirmed the effectiveness of taVNS against DMH induced colon cancer. The present study established taVNS as a novel and non-invasive approach toward the management of CRC.
Published: 2019
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21. Phase transitions and correlations in fracture processes where disorder and stress compete

Author: Santanu Sinha, Subhadeep Roy, and Alex Hansen
Subjects: Physics, QC1-999
Abstract: We study the effect of the competition between disorder and stress enhancement in fracture processes using the local load sharing fiber bundle model, a model that hovers on the border between analytical tractability and numerical accessibility. We implement a disorder distribution with one adjustable parameter. The model undergoes a localization transition as a function of this parameter. We identify an order parameter for this transition and find that the system is in the localized phase over a finite range of values of the parameter bounded by a transition to the nonlocalized phase on both sides. The transition is of first order at one side and of second order at the other. The critical exponents characterizing the second-order transition are close to those characterizing the percolation transition. We determine the spatiotemporal correlation function in the localized phase. It is characterized by two power laws as in invasion percolation. We find exponents that are consistent with the values found in that problem.
Published: 2020
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22. Creep failure in a threshold-activated dynamics: Role of temperature during a subcritical loading

Author: Subhadeep Roy and Takahiro Hatano
Subjects: Physics, QC1-999
Abstract: Creep is a time-dependent deformation of solids at relatively low stresses, leading to the breakdown with time. Here we propose a simple model for creep failure of disordered solids in which temperature and stress are controllable. Despite its simplicity, this model can reproduce most experimental observations: Distribution of the creep lifetime obeys the log-normal distribution, and the average creep lifetime decays in a scale-free manner with the increasing stress. Finally, to characterize the failure abruptness, the average breakdown frequency is introduced as an order parameter, which exhibits a series of jumps with varying temperature. Finite-size scaling holds for these jumps, implying the existence of nonequilibrium transitions.
Published: 2020
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23. DuCLOX-2/5 Inhibition Attenuates Inflammatory Response and Induces Mitochondrial Apoptosis for Mammary Gland Chemoprevention

Author: Swetlana Gautam, Atul K. Rawat, Shreesh R. Sammi, Subhadeep Roy, Manjari Singh, Uma Devi, Rajnish K. Yadav, Lakhveer Singh, Jitendra K. Rawat, Mohd N. Ansari, Abdulaziz S. Saeedan, Dinesh Kumar, Rakesh Pandey, and Gaurav Kaithwas
Subjects: DuCLOX-2/5 inhibition, angiogenesis, apoptosis, cyclooxygenase, lipoxygenase, NMR, Therapeutics. Pharmacology, RM1-950
Abstract: The present study is a pursuit to define implications of dual cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) (DuCLOX-2/5) inhibition on various aspects of cancer augmentation and chemoprevention. The monotherapy and combination therapy of zaltoprofen (COX-2 inhibitor) and zileuton (5-LOX inhibitor) were validated for their effect against methyl nitrosourea (MNU) induced mammary gland carcinoma in albino wistar rats. The combination therapy demarcated significant effect upon the cellular proliferation as evidenced through decreased in alveolar bud count and restoration of the histopathological architecture when compared to toxic control. DuCLOX-2/5 inhibition also upregulated levels of caspase-3 and caspase-8, and restored oxidative stress markers (GSH, TBARs, protein carbonyl, SOD and catalase). The immunoblotting and qRT-PCR studies revealed the participation of the mitochondrial mediated death apoptosis pathway along with favorable regulation of COX-2, 5-LOX. Aforementioned combination restored the metabolic changes to normal when scrutinized through 1H NMR studies. Henceforth, the DuCLOX-2/5 inhibition was recorded to import significant anticancer effects in comparison to either of the individual treatments.
Published: 2018
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24. Failure time in heterogeneous systems

Author: Subhadeep Roy, Soumyajyoti Biswas, and Purusattam Ray
Subjects: Physics, QC1-999
Abstract: We show that the failure time τ_{f} in the fiber bundle model, taken as a prototype of heterogeneous materials, depends crucially on the strength of the disorder δ and the stress release range R in the model. In the mean-field limit, the distribution of τ_{f} is log-normal. In this limit, the average failure time shows the variation τ_{f}∼L^{α(δ)}, where L is the system size. The exponent α has a constant value above a critical disorder δ_{c} (=1/6), while it is an increasing function of δ in the region δ
Published: 2019
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25. Synthesis of DNA/RNA and Their Analogs via Phosphoramidite and H-Phosphonate Chemistries

Author: Subhadeep Roy and Marvin Caruthers
Subjects: DNA, RNA, phosphoramidites, H-phosphonates, boranephosphonates, metallophosphonates, boranealkylphosphines, Organic chemistry, QD241-441
Abstract: The chemical synthesis of DNA and RNA is universally carried out using nucleoside phosphoramidites or H-phosphonates as synthons. This review focuses on the phosphorus chemistry behind these synthons and how it has been developed to generate procedures whereby yields per condensation approach 100% with very few side products. Additionally the synthesis and properties of certain DNA and RNA analogs that are modified at phosphorus will also be discussed. These analogs include boranephosphonates, metallophosphonates, and alkylboranephosphines.
Published: 2013
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26. Test Time Adaptation for Blind Image Quality Assessment.

Author: Subhadeep Roy, Shankhanil Mitra, Soma Biswas, and Rajiv Soundararajan
Published: 2023
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27. Mechanistic crosstalk of extracellular calcium-mediated regulation of maturation and plasticity in human monocytes

Author: Subhadeep Roy, Aarushi Sharma, and Sourabh Ghosh
Subjects: Biophysics, Cell Biology, Molecular Biology, Biochemistry
Abstract: Innate immune cells play a pivotal role in controlling tissue repair and rejection after biomaterial implantation. Calcium supplementation regulates cellular responses and alter the pathophysiology of various diseases. A series of macrophage activations through differential plasticity has been observed after cell-to-material interactions. We investigated the role of calcium supplementation in controlling macrophage phenotypes in pro-inflammatory and pre-reparative states. Oxidative defence and mitochondria involvement in cellular plasticity and the sequential M0 to M1 and M1 to M2 transitions were observed after calcium supplementation. This study describes the molecular mechanism of reactive oxygen species and drives the interconnected cellular plasticity of macrophages in the presence of calcium. Gene expression, and immunostaining, revealed a relationship between MHC class II maturation and cellular plasticity. This study elucidated the role of controlled calcium supplementation under various conditions. These findings underscore the molecular mechanism of calcium-mediated immune induction and its favourable use in different calcium-containing biomaterials., essential for tissue regeneration.
Published: 2023

28. Experimental Models for Autism Spectrum Disorder Follow-Up for the Validity

Author: Uma Devi, Vikas Kumar, Pushpraj S Gupta, Suchita Dubey, Manjari Singh, Swetlana Gautam, Jitendra K Rawat, Subhadeep Roy, Rajnish Kumar Yadav, Mohd Nazam Ansari, Abdulaziz S. Saeedan, and Gaurav Kaithwas
Abstract: Autism spectrum disorders (ASDs) are often considered to be genetic. They are characterized by unificational behavioral abnormalities which are classified in two basic domains: social relations and social communication, and restricted and repetitive pattern of behaviors and activity. Clinical research has evidenced that genetic and environmental factors play a major role in the development of ASD, and it is contemplated to be a multifactorial as well. Augmentation in the field of molecular genetics and neuroscience allows the pharmacologist to explore more features of ASDs using genetic, humanoid, and nonhumanoid models. Hence, the present review was undertaken to elucidate the major concepts associated with the models of ASD, such as gene or chromosome incrimination; face, predict, and construct validities; behavioral assays; and advantages and disadvantages of preclinical models along with constrains in developing genetic models for ASD.
Published: 2016
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29. Regulation of Transactivation at C-TAD Domain of HIF-1α by Factor-Inhibiting HIF-1α (FIH-1): A Potential Target for Therapeutic Intervention in Cancer

Author: Soniya Rani, Subhadeep Roy, Manjari Singh, and Gaurav Kaithwas
Subjects: Aging, Cell Biology, General Medicine, Biochemistry
Abstract: Hypoxia-inducible factor-1alpha (HIF-1α) is a major transcription factor that adapts to low oxygen homeostasis and regulates the expression of several hypoxic genes, which aid in cancer survival and development. It has recently piqued the interest of translational researchers in the disciplines of cancer sciences. Hypoxia triggers an ample adaptive mechanism mediated via the HIF-1α transcriptional domain. Anaerobic glycolysis, angiogenesis, metastasis, and mitophagy are adaptive mechanisms that support tumor survival by promoting oxygen supply and regulating oxygen demand in hypoxic tumor cells. Throughout this pathway, the factor-inhibiting HIF-1α is a negative regulator of HIF-1α leading to its hydroxylation at the C-TAD domain of HIF-1α under normoxia. Thus, hydroxylated HIF-1α is unable to proceed with the transcriptional events due to interference in binding of C-TAD and CBP/p300. From this review, we can hypothesize that remodeling of FIH-1 activity is a unique mechanism that decreases the transcriptional activity of HIF-1α and, as a result, all of its hypoxic consequences. Hence, this review manuscript details the depth of knowledge of FIH-1 on hypoxia-associated cellular and molecular events, a potential strategy for targeting hypoxia-induced malignancies.
Published: 2022

30. Rheology of Immiscible Two-phase Flow in Mixed Wet Porous Media: Dynamic Pore Network Model and Capillary Fiber Bundle Model Results

Author: Subhadeep Roy, Alex Hansen, Hursanay Fyhn, and Santanu Sinha
Subjects: Pressure drop, Materials science, Capillary action, General Chemical Engineering, Flow (psychology), Fluid Dynamics (physics.flu-dyn), FOS: Physical sciences, Physics - Fluid Dynamics, Mechanics, Catalysis, Volumetric flow rate, Physics::Fluid Dynamics, Rheology, Wetting, Two-phase flow, Porous medium
Abstract: Immiscible two-phase flow in porous media with mixed wet conditions was examined using a capillary fiber bundle model, which is analytically solvable, and a dynamic pore network model. The mixed wettability was implemented in the models by allowing each tube or link to have a different wetting angle chosen randomly from a given distribution. Both models showed that mixed wettability can have significant influence on the rheology in terms of the dependence of the global volumetric flow rate on the global pressure drop. In the capillary fiber bundle model, for small pressure drops when only a small fraction of the tubes were open, it was found that the volumetric flow rate depended on the excess pressure drop as a power law with an exponent equal to 3/2 or 2 depending on the minimum pressure drop necessary for flow. When all the tubes were open due to a high pressure drop, the volumetric flow rate depended linearly on the pressure drop, independent of the wettability. In the transition region in between where most of the tubes opened, the volumetric flow depended more sensitively on the wetting angle distribution function and was in general not a simple power law. The dynamic pore network model results also showed a linear dependence of the flow rate on the pressure drop when the pressure drop is large. However, out of this limit the dynamic pore network model demonstrated a more complicated behaviour that depended on the mixed wettability condition and the saturation. In particular, the exponent relating volumetric flow rate to the excess pressure drop could take on values anywhere between 1.0 and 1.8. The values of the exponent were highest for saturations approaching 0.5, also, the exponent generally increased when the difference in wettability of the two fluids were larger and when this difference was present for a larger fraction of the porous network., 23 pages, 9 figures
Published: 2021

31. Modeling and Tracking of Underground Cable Fault Using Genetic Algorithm

Author: Sanhita Mishra, Subhadeep Roy, Sarat Chandra Swain, and Aurobinda Routray
Published: 2022

32. Performance Bounds for Turbo Coded Half Duplex Relay Systems.

Author: Subhadeep Roy and Tolga M. Duman
Published: 2006
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33. A sub-word-parallel Galois field multiply-accumulate unit for digital signal processors.

Author: Subhadeep Roy
Published: 2005
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34. Stochastic power control for CDMA over Rayleigh fading channels.

Author: Subhadeep Roy and Tolga M. Duman
Published: 2004
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35. Development of a biomimetic arch-like 3D bioprinted construct for cartilage regeneration using gelatin methacryloyl and silk fibroin-gelatin bioinks

Author: Juhi Chakraborty, Julia Fernández-Pérez, Kenny A van Kampen, Subhadeep Roy, Tim ten Brink, Carlos Mota, Sourabh Ghosh, and Lorenzo Moroni
Subjects: 3D bioprinting, HEDGEHOG, collagen network, Wnt/beta-catenin, FABRICATION, Biomedical Engineering, Bioengineering, ARTICULAR-CARTILAGE, ORGANIZATION, General Medicine, Biochemistry, COLLAGEN, MESENCHYMAL STEM-CELLS, Biomaterials, DIFFERENTIATION, CHONDROGENESIS, TISSUE, arch architecture, silk fibroin-gelatin, TGF-beta, MATRIX, gelatin methacryloyl, Biotechnology
Abstract: In recent years, engineering biomimetic cellular microenvironments have been a top priority for regenerative medicine. Collagen II, which is arranged in arches, forms the predominant fiber network in articular cartilage. Due to the shortage of suitable microfabrication techniques capable of producing 3D fibrous structures, in vitro replication of the arch-like cartilaginous tissue constitutes one of the major challenges. Hence, in the present study, we report a 3D bioprinting approach for fabricating arch-like constructs using two types of bioinks, gelatin methacryloyl (GelMa) and silk fibroin-gelatin (SF-G). The bioprinted SF-G constructs displayed increased proliferation of the encapsulated human bone marrow-derived mesenchymal stem cells compared to the GelMA constructs. Biochemical assays, gene, and protein expression exhibited the superior role of SF-G in forming the fibrous collagen network and chondrogenesis. Protein-protein interaction study using Metascape evaluated the function of the proteins involved. Further GeneMANIA and STRING analysis using Col 2A1, SOX 9, ACAN, and the genes upregulated on day 21 in RT-PCR, i.e. β-catenin, TGFβR1, Col 1A1 in SF-G and PRG4, Col 10A1, MMP 13 in GelMA validated our in vitro results. These findings emphasized the role of SF-G in regulating the Wnt/β-catenin and TGF-β signaling pathways. Hence, the 3D bioprinted arch-like constructs possess a substantial potential for cartilage regeneration.
Published: 2023

36. Stress-Induced Haematohidrosis: a Case Report

Author: Sayantanava Mitra, Seshadri Sekhar Chatterjee, Subhadeep Roy, and Manoj Kumar
Published: 2022

37. Modeling crack propagation in heterogeneous materials: Griffith's law, intrinsic crack resistance and avalanches

Author: Subhadeep, Roy, Takahiro, Hatano, and Purusattam, Ray
Subjects: Condensed Matter::Materials Science, Statistical Mechanics (cond-mat.stat-mech), mental disorders, FOS: Physical sciences, Physics::Classical Physics, Condensed Matter - Statistical Mechanics, Physics::Geophysics
Abstract: Various kinds of heterogeneity in solids including atomistic discreteness affect the fracture strength as well as the failure dynamics remarkably. Here we study the effects of an initial crack in a discrete model for fracture in heterogeneous materials, known as the fiber bundle model. We find three distinct regimes for fracture dynamics depending on the initial crack size. If the initial crack is smaller than a certain value, it does not affect the rupture dynamics and the critical stress. While for a larger initial crack, the growth of the crack leads to a breakdown of the entire system, and the critical stress depends on the crack size in a power-law manner with a nontrivial exponent. The exponent, as well as the limiting crack size, depend on the strength of heterogeneity and the range of stress relaxation in the system., 12 pages, 6 figures
Published: 2022

38. Underground Cable Fault Tracking by Ant Colony Optimization

Author: Sanhita Mishra, Subhadeep Roy, S.C. Swain, and Aurobinda Routray
Published: 2022

39. Mitochondrial apoptosis and curtailment of hypoxia‐inducible factor‐1α/fatty acid synthase: A dual edge perspective of gamma linolenic acid in ER+ mammary gland cancer

Author: Dinesh Kumar, Gaurav Kaithwas, Subhadeep Roy, Manjari Singh, and Atul Rawat
Subjects: 0301 basic medicine, Clinical Biochemistry, Cell, Antineoplastic Agents, Apoptosis, Breast Neoplasms, Biochemistry, Palmitic acid, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Tumor Cells, Cultured, medicine, Humans, gamma-Linolenic Acid, gamma-Linolenic acid, Carcinogen, Cell Proliferation, Membrane Potential, Mitochondrial, biology, Cell Cycle, Methylnitrosourea, Cell Biology, General Medicine, Phosphatidylserine, Cell cycle, Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, Mitochondria, Fatty acid synthase, 030104 developmental biology, medicine.anatomical_structure, Microscopy, Fluorescence, chemistry, 030220 oncology & carcinogenesis, MCF-7 Cells, biology.protein, Female, Fatty Acid Synthases
Abstract: Gamma linolenic acid is a polyunsaturated fatty acid having selective anti-tumour properties with negligible systemic toxicity. In the present study, the anti-cancer potential of gamma linolenic acid and its effects on mitochondrial as well as hypoxia-associated marker was evaluated. The effect of gamma linolenic acid was scrutinised against ER + MCF-7 cells by using fluorescence microscopy, JC-1 staining, dot plot assay and cell cycle analysis. The in vitro results were also confirmed using carcinogen (n-methyl-n-nitrosourea) induced in vivo model. The early and late apoptotic signals in the conjugation with mitochondrial depolarisation were found once scrutinised through mitochondrial membrane potential and life death staining after gamma linolenic acid treatment. Gamma linolenic acid arrested the cell cycle in G0/G1 phase with the majority of cell populations in the early apoptotic stage. The translocation of phosphatidylserine was studied through annexin-V FITC dot plot assay. The markers of cellular proliferation (decreased alveolar bud count, histopathological architecture restoration and loss of tumour micro-vessels) were diminished after gamma linolenic acid treatment. Gamma linolenic acid ameliorates the biological effects of n-methyl-n-nitrosourea persuading the mitochondrial mediated death pathway and impeding the hypoxic microenvironment to make a halt in palmitic acid synthesis. SIGNIFICANCE: The present study elaborates the effect of gamma linolenic acid on mammary gland cancer by following mitochondrial-mediated death apoptosis pathway. Gamma linolenic acid also inhibits cell-wall synthesis by the curtailment of HIF-1α and FASN level in mammary gland cancer.
Published: 2020

40. Regulation of decellularized matrix mediated immune response

Author: Juhi Chakraborty, Subhadeep Roy, and Sourabh Ghosh
Subjects: 0303 health sciences, Decellularization, Tissue Engineering, Tissue Scaffolds, Decellularized matrix, Biomedical Engineering, 02 engineering and technology, Biology, 021001 nanoscience & nanotechnology, Acquired immune system, Extracellular Matrix, Cell biology, Extracellular matrix, 03 medical and health sciences, Immune system, Host vs Graft Reaction, Animals, Humans, Macrophage, Cellular antigens, Acellular Dermis, General Materials Science, 0210 nano-technology, Reprogramming, 030304 developmental biology
Abstract: The substantially growing gap between suitable donors and patients waiting for new organ transplantation has compelled tissue engineers to look for suitable patient-specific alternatives. Lately, a decellularized extracellular matrix (dECM), obtained primarily from either discarded human tissues/organs or other species, has shown great promise in the constrained availability of high-quality donor tissues. In this review, we have addressed critical gaps and often-ignored aspects of understanding the innate and adaptive immune response to the dECM. Firstly, although most of the studies claim preservation of the ECM ultrastructure, almost all methods employed for decellularization would inevitably cause a certain degree of disruption to the ECM ultrastructure and modulation in secondary conformations, which may elicit a distinct immunogenic response. Secondly, it is still a major challenge to find ways to conserve the native biochemical, structural and biomechanical cues by making a judicious decision regarding the choice of decellularization agents/techniques. We have critically analyzed various decellularization protocols and tried to find answers on various aspects such as whether the secondary structural conformation of dECM proteins would be preserved after decellularization. Thirdly, to keep the dECM ultrastructure as close to the native ECM we have raised the question "How good is good enough?" Even residual cellular antigens or nucleic acid fragments may elicit antigenicity leading to a low-grade immune response. A combinative knowledge of macrophage plasticity in the decellularized tissue and limits of decellularization will help achieve the native ultrastructure. Lastly, we have shifted our focus on the scientific basis of the presently accepted criteria for decellularization, and the effect on immune response concerning the interaction between the decellularized extracellular matrix and macrophages with the subsequent influence of T-cell activation. Amalgamating suitable decellularization approaches, sufficient knowledge of macrophage plasticity and elucidation of molecular pathways together will help fabricate functional immune informed decellularized tissues in vitro that will have substantial implications for efficient clinical translation and prediction for in vivo reprogramming and tissue regeneration.
Published: 2020

41. 3D printed hydroxyapatite promotes congruent bone ingrowth in rat load bearing defects

Author: Juhi Chakraborty, Subhadeep Roy, and Sourabh Ghosh
Subjects: Biomaterials, Weight-Bearing, Bone Regeneration, Durapatite, Tissue Scaffolds, Printing, Three-Dimensional, Biomedical Engineering, Animals, Humans, Bioengineering, X-Ray Microtomography, Porosity, Rats
Abstract: 3D porous hydroxyapatite (HAP) scaffolds produced by conventional foaming processes have limited control over the scaffold’s pore size, geometry, and pore interconnectivity. In addition, random internal pore architecture often results in limited clinical success. Imitating the intricate 3D architecture and the functional dynamics of skeletal deformations is a difficult task, highlighting the necessity for a custom-made, on-demand tissue replacement, for which 3D printing is a potential solution. To combat these problems, here we report the ability of 3D printed HAP scaffolds for in vivo bone regeneration in a rat tibial defect model. Rapid prototyping using the direct-write technique to fabricate 25 mm2 HAP scaffolds were employed for precise control over geometry (both external and internal) and scaffold chemistry. Bone ingrowth was determined using histomorphometry and a novel micro-computed tomography (micro-CT) image analysis. Substantial bone ingrowth was observed in implants that filled the defect site. Further validating this quantitatively by micro-CT, the Bone mineral density (BMD) of the implant at the defect site was 1024 mgHA ccm−1, which was approximately 61.5% more than the BMD found with the sham control at the defect site. In addition, no evident immunoinflammatory response was observed in the hematoxylin and eosin micrographs. Interestingly, the present study showed a positive correlation with the outcomes obtained in our previous in vitro study. Overall, the results suggest that 3D printed HAP scaffolds developed in this study offer a suitable matrix for rendering patient-specific and defect-specific bone formation and warrant further testing for clinical application.
Published: 2022

42. Opinion dynamics: Public and private

Author: Subhadeep Roy and Soumyajyoti Biswas
Subjects: Physics - Physics and Society, Consensus, Attitude, General Mathematics, General Engineering, Humans, FOS: Physical sciences, General Physics and Astronomy, Physics and Society (physics.soc-ph)
Abstract: We study here the dynamics of opinion formation in a society where we take into account of the internally held beliefs and externally expressed opinions of the individuals, which are not necessarily the same at all times. While these two components can influence one another, their difference, both in dynamics and in the steady state, poses interesting scenarios in terms of the transition to consensus in the society and characterizations of such consensus. Here we study this public and private opinion dynamics and the critical behavior of the consensus forming transitions, using a kinetic exchange model., 13 pages, 9 figures, accepted for publication in Phil. Trans. R. Soc. A
Published: 2021

43. Kaon-proton strong interaction at low relative momentum via femtoscopy in Pb-Pb collisions at the LHC

Author: Rafael Peretti Pezzi, Leticia Cunqueiro Mendez, Maya Hachiya Shimomura, Anton Jusko, Raul Arteche Diaz, Lukas Lautner, Jaehyun Kim, In Kwon Yoo, Ivan Kralik, Miroslav Pikna, Mario Sitta, Giacomo Contin, David Karatovic, Saul Anibal Rodriguez Ramirez, Raphaelle Marie Bailhache, Zebo Tang, Elisa Meninno, Linda Vickovic, Nicolo Jacazio, Jochen Klein, Ermanno Vercellin, Tatiana Lazareva, Chun-Lu Huang, S. R. Klein, Bharati Naik, Kirill Lapidus, Rihan Haque, Christian Holm Christensen, Trine Spedstad Tveter, Gianluca Aglieri Rinella, Ivan Kisel, Petr Zavada, Christina Markert, Michelangelo Agnello, Leo Clifford Greiner, Stefano Piano, Evgeny Kryshen, David Dobrigkeit Chinellato, Sarah Louise La Pointe, Germano Bonomi, Przemyslaw Stefan Rokita, Ian Gardner Bearden, Eszter Frajna, Daiki Sekihata, Giuseppe Eugenio Bruno, Michael Rudolf Ciupek, Peter Glassel, Francesca Ercolessi, Lukas Nellen, David Olle Rickard Silvermyr, Bartosz Balis, Sven Gotovac, Zabulon Vilakazi, Victor Jose Gaston Feuillard, Roman Lavicka, Arturo Alejandro Menchaca-Rocha, Pritam Chakraborty, Marek Bombara, Ernst Hellbar, Jan Jadlovsky, Dhruv Utpalkumar Dixit, Andreas Michael Mathis, Ganesh Jagannath Tambave, Alexey Kuryakin, Hannah Bossi, Ahsan Mehmood Khan, Vladimir Vechernin, Yasir Ali, Jon-Are Saetre, Eugenio Nappi, Kristjan Herlache Gulbrandsen, Satoshi Yano, Monika Varga-Kofarago, Daniel Berenyi, Johannes Peter Wessels, Martin Schmidt, Peter Christiansen, Pietro Fecchio, Philippe Pillot, Fabio de Moraes Canedo, Silvia Delsanto, Piotr Jan Gasik, Vikas Singhal, Pablo Fierro Rojas, Tinku Sarkar Sinha, Vitaly Okorokov, Roberto Preghenella, Antonino Zichichi, Jorge Andres Lopez Lopez, Guillaume Taillepied, Matteo Concas, Irais Bautista Guzman, Paolo Martinengo, Laszlo Gyulai, Marcelo Gameiro Munhoz, C. Ceballos Sanchez, Laura Serksnyte, Lucia Anna Husova, Gabriel Garcia Guardiano, N. Bianchi, Bhawani Singh, Mihail Bogdan Blidaru, Henner Buesching, Andry Malala Rakotozafindrabe, Tuva Ora Herenui Richert, Siyu Tang, Benedikt Volkel, Michal Sumbera, F. Krizek, Boris Batyunya, Shiming Yuan, Mario Ivan Martinez Hernandez, Panagiotis Christakoglou, Jonghan Park, Samsul Islam, Baidyanath Sahoo, Dukhishyam Mallick, Anastasia Berdnikova, Anju Bhasin, Somnath Kar, Nicola Funicello, Nora De Marco, Fernando Torales Acosta, Rosario Turrisi, Wenjing Deng, Krzysztof Redlich, Evgeny Kondratyuk, Yanchun Ding, Sami Sakari Rasanen, Joakim Nystrand, Juan Manuel Mejia Camacho, David H. Evans, Haakon Andre Reme-Ness, Adam Ryszard Kisiel, Zuzana Jakubcinova, Aude Marie Camille Glaenzer, Ivan Vorobyev, Olja Dordic, Oton Vazquez Doce, Jin Joo Seo, Alessandro Grelli, Naomi van der Kolk, Cindy Mordasini, Vladimir Kaplin, Antoine Jean-Simon Junique, Lucas Altenkamper, Antonio Carlos Oliveira da Silva, Mikhail Malaev, Yitao Wu, Yasuo Miake, Sinjini Chandra, Vojtech Petracek, Andrea Ferrero, Lucrezia Camilla Migliorin, Javier Ernesto Castillo Castellanos, Stefano Trogolo, Patrick Simon Reichelt, Hikari Murakami, Jørgen André Lien, William Edward Witt, Ionel Stan, Mohammed Hamid, Antonio Ortiz Velasquez, Luigi Dello Stritto, Roy Crawford Lemmon, Jana Bielcikova, Guillermo Tejeda Munoz, Costin Grigoras, Marielle Chartier, Alberto Martin Gago Medina, Raimond Snellings, Julian Wojciech Myrcha, Marek Kowalski, Arthur Willem Jean Gal, Rainer Arno Ernst Renfordt, Petr Nomokonov, Anik Gupta, Debjani Banerjee, Alexander Kluge, Jian Liu, Alexey Kurepin, C. Suire, Alexander Adler, Fernando Antonio Flor, Sebastien Perrin, Zubayer Ahammed, Alessandro Balbino, Ulrich Fuchs, Corrado Gargiulo, Evgeny Ryabinkin, Davide Caffarri, Dagmar Adamová, Nicolo' Valle, Siegfried Valentin Foertsch, Paolo Giubellino, Pierre Vande Vyvre, Yury Ryabov, Adam Tadeusz Wegrzynek, Bruno Espagnon, Philippe Crochet, Giacomo Vito Margagliotti, Ida Storehaug, Eugen Mudnic, Sourav Kundu, Meike Charlotte Danisch, Roman Rogalev, Prottoy Das, Robert Vertesi, Bjarte Kileng, David Horak, Rashmi Raniwala, Anantachai Lakrathok, Fabian Pliquett, Mikolaj Krzewicki, Luca Quaglia, Sebastian Hornung, Claude Andre Pruneau, Sarita Sahoo, Hanna Paulina Zbroszczyk, Toru Sugitate, Martin Poghosyan, Roberto Barbera, Dimitar Lubomirov Mihaylov, Johan Alme, Luciano Ramello, Florian Herrmann, Massimo Lamanna, Barbara Jacak, Diego Stocco, Alexander Philipp Kalweit, Omar Vazquez Rueda, Daicui Zhou, Se Yong Kim, Livio Bianchi, Shi Qiu, Jacek Tomasz Otwinowski, Vasco Miguel Chibante Barroso, Luca Barioglio, Brigitte Cheynis, Elena Botta, Ola Slettevoll Groettvik, Manuel Colocci, Jaehyeon Do, Solangel Rojas Torres, Masanori Ogino, Anna Onnerstad, Yue Shi Lai, Yajun Mao, Amelia Lindner, Dmitry Finogeev, Annalisa De Caro, Daniel Michael Muhlheim, Raffaele Grosso, Giuseppe Mandaglio, Sebastian Dominik Koryciak, Jungeol Kim, Kamil Rafal Deja, Laura Helena Gonzalez Trueba, Zhongbao Yin, Jerome Jung, Zhanna Khabanova, Uliana Dmitrieva, Ketil Roeed, Salvatore De Pasquale, Teodor Siemiarczuk, Ester Anna Rita Casula, Joshua Leon Konig, Yury Pestov, Bushra Ali, Sarah Julie Porteboeuf, Maria Barlou, Sanjib Muhuri, Anjali Sharma, Erin Frances Gauger, Marco Toppi, Marian Krivda, Subhadeep Roy, Negin Alizadehvandchali, Federico Cindolo, Liudmila Malinina, Daniel Jia Qin Goh, Tonatiuh Garcia Chavez, Thomas Klemenz, Christophe Furget, Jean Willy Andre Cleymans, Volker Lindenstruth, Francesca Soramel, Grzegorz Andrzej Wilk, Mario Kruger, Antonio Di Mauro, Federico Ronchetti, Norbert Novitzky, Vit Kucera, Jhuma Ghosh, Sabyasachi Siddhanta, Premomoy Ghosh, Maurice Louis Coquet, Miljenko Suljic, Smbat Grigoryan, Gvozden Neskovic, Philip Hauer, Matthias Richter, Rainer Martin Schicker, Rabi Soto Camacho, Dieter Roehrich, Subhasis Chattopadhyay, Muhammad Umair Naru, Barbara Antonina Trzeciak, Xing Long Li, Jaime Norman, Michael Jung, Thorsten Sven Kollegger, Alexander Bolozdynya, Christopher Hills, Dushmanta Sahu, Alla Maevskaya, Jeremy John Wilkinson, Meenakshi Sharma, Konstantin Mikhaylov, T. Dietel, R. J. Ehlers, Alberto Caliva, Henrique Jose Correia Zanoli, Domenico Colella, Anselmo Margotti, Youngil Kwon, Andrey Zarochentsev, Nicolas Schmidt, Dezso Varga, Shaista Khan, Felix Reidt, Ramona Lea, Jonathan Samuel Colburn, F. Bock, Ante Bilandzic, Christoph Mayer, Ernesto Calvo Villar, Alex Henri Jean Chauvin, Joyful Elma Mdhluli, Stefano Politano, D. De Gruttola, Jens Robert Luhder, Marten Ole Schmidt, Sergio Paisano Guzman, Mihai Petrovici, Anisa Khatun, Iwona Anna Sputowska, Rosario Nania, Florian Jonas, Alberto Masoni, Chiara Oppedisano, Martin Andreas Volkl, Vladimir Samsonov, Christine Nattrass, Carlos Soncco Meza, Junjie Zhu, Ara Grigoryan, Ana Maria Marin, Mirko Planinic, A. Matyja, Jamila Bashir Butt, Emma Gonzalez Hernandez, Alessandro Ferretti, Janusz Oleniacz, Lawrence Pinsky, Ritsuya Hosokawa, Pooja Pareek, Deekshit Kumar, Chiara Pinto, Raghunath Sahoo, Valerie Ramillien Barret, Bernd Stefan Windelband, Josephina Rae Wright, Varlen Grabski, Antonio Lafuente Mazuecos, Bong-Hwi Lim, Feng Fan, P. G. Jones, Hadi Hassan, Andre Augustinus, L. Betev, M. Mohisin Khan, Borge Svane Nielsen, Thomas Peitzmann, Dmitry Budnikov, Johannes Lehrbach, Pragati Sahoo, Austin Robert Schmier, Dmitry Serebryakov, Nikola Poljak, Alexander Kurepin, Jihye Song, Boris Polishchuk, Vytautas Vislavicius, Mustafa Anaam, Igor Pshenichnov, Mikhail Zhalov, Alwina Ruixin Liu, Mohammad Al-Turany, Sang Un Ahn, Mike Henry Petrus Sas, Michael Lettrich, Kirill Voloshin, Zhi Yu, Debojit Sarkar, Andreas Morsch, Jose Luis Bazo Alba, Natasha Sharma, Neelkamal Mallick, Shingo Sakai, Dimitra Andreou, Austin Vincent Harton, Attiq Ur Rehman, Marie Germain, I. Das, Silvia Arcelli, Adrian Florin Mechler, V. Muccifora, Ranbir Singh, Simon Voigt Nesbø, Monika Joanna Jakubowska, Cynthia Marie Hadjidakis, Tomas Herman, Filip Erhardt, Filippo Baruffaldi, Xinye Peng, Valentina Zaccolo, Hans Rudolf Schmidt, Marek Gorgon, Lee Stuart Barnby, Wenya Wu, Francesca Bellini, Pradip Kumar Sahu, Amrit Gautam, Piero Giubilato, Michael Henry Oliver, Laurent Bernard Aphecetche, Motoi Inaba, Klaus Johannes Reygers, Jin Hee Yoon, Ingrid Mckibben Lofnes, Jan Figiel, Alperen Yuncu, James Philip Iddon, Horst Sebastian Scheid, Vladimir Ivanov, Pranjal Sarma, Christian Claude Kuhn, Shreyasi Acharya, Mengke Cai, Katharina Demmich, Domenico Elia, Viljar Nilsen Eikeland, Natalia Kondratyeva, Mateusz Andrzej Ploskon, J. W. Harris, Seyed Farid Taghavi, Jan Anton Hasenbichler, Marco Giacalone, Alexandre Alarcon Do Passo Suaide, David Michael Rohr, Dariusz Czeslaw Miskowiec, Lucas Anne Vermunt, Klaus Barth, Matthew Daniel Buckland, Jinsook Kim, Romain Schotter, Laure Marie Massacrier, Artem Shangaraev, Dirk Hutter, Christian Lippmann, Luis Gustavo Pereira, Benjamin Donigus, Filippo Costa, Herve Borel, Dominik Voscek, Ilya Selyuzhenkov, Alice Elisabeth Ohlson, Jan Honermann, Sergey Filchagin, Marco Bregant, Roelof Jan Gijs van Weelden, Ezra Douglas Lesser, Alexander Vodopyanov, Oskari Antti Matti Saarimaki, Xavier Bernard Lopez, Jaroslav Bielcik, Ji-Young Kim, Ryan Patrick Hannigan, Elena Rogochaya, Bruno Alessandro, Enrico Fragiacomo, Boris Rumyantsev, S. N. Alam, Sergey Sadovskiy, Arturo Fernandez Tellez, Sergey Nikolaev, Claudiu Cornel Schiaua, Ishaan Ahuja, Karel Safarik, Andrey Erokhin, Thibaut Albert Rancien, Gergoe Hamar, Malgorzata Anna Janik, Rutuparna Rath, Hugo Denis Antonio Pereira Da Costa, Tariq Mahmoud, Arseniy Shabanov, Sylvain Chapeland, Paolo Camerini, Sergey Voloshin, Suharyo Sumowidagdo, Marta Urioni, Marian Ivanov, Silvia Masciocchi, Thomas Michael Cormier, Lokesh Kumar, Hua Pei, Andrea Danu, Sandeep Dudi, G. Bencedi, Sergio Vergara Limon, Kunal Garg, Maximiliano Puccio, Alek Hutson, H. 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Takahashi, Xiaoming Zhang, Imrich Szarka, Minjung Kim, Jurgen Schukraft, Nicole Bastid, Yifei Zhang, Andrea Alici, Angela Badala, D. H. Kim, Yaroslav Berdnikov, Igor Morozov, Madalina-Gabriela Tarzila, Andrey Kondratyev, Luisa Bergmann, Francesco Noferini, Grazia Luparello, Caitlin Beattie, Natalia Dzalaiova, Paraskevi Ganoti, Fabrizio Grosa, Gabor Biro, Jeongsu Bok, Alexander Borissov, Nataliya Topilskaya, Carlos Duarte Galvan, Buddhadeb Bhattacharjee, Boris Wagner, Peter Matthew Bond, Dmitry Yurevich Peresunko, Florian Paul Andre Damas, Ankhi Roy, Christian Klein-Boesing, Hartmut Hillemanns, Ionut Cristian Arsene, Maxime Guilbaud, Francesco Mazzaschi, Victor Trubnikov, Julien Faivre, Yves Roland Schutz, Vladislav Grigoryev, Mohamad Tarhini, Cristiane Jahnke, G.L. Usai, Dmitry Blau, Rahul Ramachandran Nair, Renu Bala, Nachiketa Sarkar, Petra Loncar, Eleazar Cuautle Flores, Corey James Myers, Thomas Janson, Sebastian Adam Bysiak, Ran Xu, Arturo Tauro, Soyeon Cho, Shinichi Hayashi, Victor Gonzalez, Alexey Bogdanov, Randhir Singh, A. Alkin, Anand Kumar Dubey, Catalin-Lucian Ristea, Swati Saha, Hiroki Yokoyama, Jacopo Pazzini, Gokhan Halimoglu, Andrea Rossi, Georgui Kornakov, Chiara Zampolli, Vitaly Loginov, Neelima Agrawal, Corrado Cicalo, Sanchari Thakur, Cristian Andrei, Venelin Anguelov, Johanna Stachel, Vikash Sumberia, Jesus Ricardo Alvarado Garcia, Marco van Leeuwen, Sergey Gorbunov, Yuko Sekiguchi, Stefan Kirsch, Antonio Trifiro, John Jowett, Sara Vallero, Auro Prasad Mohanty, Mauro Rogerio Cosentino, Yongwook Baek, Lidia Maria Gorlich, Kenneth Francis Read, Paula Fernanda Toledo Matuoka, Laura Brittany Havener, Dongfang Wang, Sergey Nikulin, Jacek Bogumil Biernat, Oeystein Djuvsland, Lukas Koska, Alexandre Shabetai, Jiyeon Kwon, Sanjay K. Ghosh, Stefano Boi, Cvetan Valeriev Cheshkov, Ildefonso Leon Monzon, Zaida Conesa del Valle, Takumi Osako, Chiara de Martin, A. R. Redelbach, Marko Jercic, Stefania Bufalino, Michal Broz, Alberto Rotondi, Radiy Ilkaev, Martino Gagliardi, Surya Prakash Pathak, Clara Bartels, Andrey Kazantsev, Sumit Kumar Saha, Sean Murray, Fouad Rami, Song Zhang, Adela Kravcakova, Jan de Cuveland, Sonali Padhan, Massimo Masera, Maksim Melnik Storetvedt, Anders Nils Erik Oskarsson, Preeti Dhankher, Oveis Sheibani, Wioleta Rzesa, D. Di Bari, Rune Langøy, Podist Kurashvili, Patrick Huhn, Roberta Arnaldi, Anuj Chandra, Slavka Jadlovska, Johann Joachim Schambach, Jose Garabatos Cuadrado, Maciej Slupecki, Jens Joergen Gaardhoeje, Fabio Filippo Colamaria, Fiorella Maria Celeste Fionda, Martin Vala, Taejun Kim, Alice Mulliri, Piotr Jan Konopka, Biswarup Paul, Sudhir Pandurang Rode, Tim Sebastian Rogoschinski, Guido Alexander Willems, Xiaozhi Bai, Kai Oliver Schweda, Robin Albert Andre Caron, Justin Thomas Blair, Haavard Helstrup, James Declan Mulligan, Giacinto de Cataldo, Evgeny Karpechev, Tomasz Trzcinski, Alessandra Maria Mazzoni, Edgar Dominguez Rosas, Ruben Shahoyan, Fabio Catalano, Markus Keil, Yu-Gang Ma, Janka Vrlakova, Peter Braun-Munzinger, Sanjeev Singh Sambyal, Anders Garritt Knospe, A. Nath, Luis Alberto Perez Moreno, Iouri Belikov, Teo Mrnjavac, Haidar Mas'Ud Alfanda, Barbara Ewa Erazmus, Sumit Basu, Roman Lietava, Beomkyu Kim, Andrea Dubla, Tebogo Joyce Shaba, You Zhou, Valeriy Pozdniakov, Jacek Kitowski, Edith Zinhle Buthelezi, Tulika Tripathy, Bedangadas Mohanty, Junlee Kim, Alexandru Florin Dobrin, Giuseppe Simonetti, Ivan Ravasenga, Michael Karim Habib, Ya Zhu, Christoph Blume, Andrzej Rybicki, Kosei Yamakawa, Lukas Kreis, Anar Rustamov, L. Fabbietti, Ralf Peter Averbeck, Zoltán Varga, Zaenal Akbar, Esther Bartsch, Adrian Sevcenco, Stefano Panebianco, Jonatan Adolfsson, Nima Zardoshti, Gilda Scioli, Gian Michele Innocenti, Jogender Saini, Christos Pliatskas Stylianidis, Christian Schmidt, Bernhard Skaali, A. R. Timmins, Soren Pontoppidan Sorensen, Sanghoon Lim, Mattia Faggin, Giacomo Volpe, Yury Kharlov, Luciano Musa, Serpil Yalcin Kuzu, Mikhail Ippolitov, Livia Terlizzi, Antonio Uras, Chunzheng Wang, Stefania Beole, Milan Tkacik, Theraa Tork, Amanda Nicole Flores, Inayat Rasool Bhat, Marta Verweij, Vladimir Izucheev, Ralf Keidel, Marc Weber, Pradip Kumar Roy, Sergey Shirinkin, Sudipan De, Peter Levai, Mesut Arslandok, R. 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Klay, Jinjin Pan, Yury Melikyan, Vivek Singh, Martin Kroesen, Gustavo Conesa Balbastre, Nikolai Smirnov, Artem Isakov, Sheetal Sharma, Raphael Noel Tieulent, Bernhard Franz Ketzer, Mihaela Gabriela Besoiu, Miroslaw Jablonski, Alberica Toia, Magnus Mager, Pietro Antonioli, Luisa Cifarelli, Qiye Shou, Reynier Cruz Torres, Markus Ball, Despina Hatzifotiadou, Jasper Elias Parkkila, Harald Appelshaeuser, Guillermo Mesa Perez, Georgijs Skorodumovs, Oleksandr Kovalenko, Wadut Shaikh, Giuseppe Trombetta, Peter Martin Jacobs, Jon Christopher Wikne, Alessandro De Falco, Gioacchino Vino, S. T. Heckel, Charles E. 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T., Matyja, A., Mayer, C., Mazuecos, A. L., Mazzaschi, F., Mazzilli, M., Mazzoni, M. A., Mdhluli, J. E., Mechler, A. F., Meddi, F., Melikyan, Y., Menchaca-Rocha, A., Meninno, E., Menon, A. S., Meres, M., Mhlanga, S., Miake, Y., Micheletti, L., Migliorin, L. C., Mihaylov, D. L., Mikhaylov, K., Mishra, A. N., Mi??kowiec, D., Modak, A., Mohanty, A. P., Mohanty, B., Mohisin Khan, M., Moravcova, Z., Mordasini, C., Moreira De Godoy, D. A., Moreno, L. A. P., Morozov, I., Morsch, A., Mrnjavac, T., Muccifora, V., Mudnic, E., M??hlheim, D., Muhuri, S., Mulligan, J. D., Mulliri, A., Munhoz, M. G., Munzer, R. H., Murakami, H., Murray, S., Musa, L., Musinsky, J., Myers, C. J., Myrcha, J. W., Naik, B., Nair, R., Nandi, B. K., Nania, R., Nappi, E., Naru, M. U., Nassirpour, A. F., Nath, A., Nattrass, C., Neagu, A., Nellen, L., Nesbo, S. V., Neskovic, G., Nesterov, D., Nielsen, B. S., Nikolaev, S., Nikulin, S., Nikulin, V., Noferini, F., Noh, S., Nomokonov, P., Norman, J., Novitzky, N., Nowakowski, P., Nyanin, A., Nystrand, J., Ogino, M., Ohlson, A., Okorokov, V. A., Oleniacz, J., Oliveira Da Silva, A. C., Oliver, M. H., Onnerstad, A., Oppedisano, C., Ortiz Velasquez, A., Osako, T., Oskarsson, A., Otwinowski, J., Oyama, K., Pachmayer, Y., Padhan, S., Pagano, D., Pai??, G., Palasciano, A., Pan, J., Panebianco, S., Pareek, P., Park, J., Parkkila, J. E., Pathak, S. P., Patra, R. N., Paul, B., Pazzini, J., Pei, H., Peitzmann, T., Peng, X., Pereira, L. G., Pereira Da Costa, H., Peresunko, D., Perez, G. M., Perrin, S., Pestov, Y., Petr????ek, V., Petrovici, M., Pezzi, R. P., Piano, S., Pikna, M., Pillot, P., Pinazza, O., Pinsky, L., Pinto, C., Pisano, S., P??osko??, M., Planinic, M., Pliquett, F., Poghosyan, M. G., Polichtchouk, B., Politano, S., Poljak, N., Pop, A., Porteboeuf-Houssais, S., Porter, J., Pozdniakov, V., Prasad, S. 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B., Skorodumovs, G., Slupecki, M., Smirnov, N., Snellings, R. J. M., Soncco, C., Song, J., Songmoolnak, A., Soramel, F., Sorensen, S., Sputowska, I., Stachel, J., Stan, I., Steffanic, P. J., Stiefelmaier, S. F., Stocco, D., Storehaug, I., Storetvedt, M. M., Stylianidis, C. P., Suaide, A. A. P., Sugitate, T., Suire, C., Suljic, M., Sultanov, R., umbera, M., Sumberia, V., Sumowidagdo, S., Swain, S., Szabo, A., Szarka, I., Tabassam, U., Taghavi, S. F., Taillepied, G., Takahashi, J., Tambave, G. J., Tang, S., Tang, Z., Tarhini, M., Tarzila, M. G., Tauro, A., Tejeda Mu??oz, G., Telesca, A., Terlizzi, L., Terrevoli, C., Tersimonov, G., Thakur, S., Thomas, D., Tieulent, R., Tikhonov, A., Timmins, A. R., Tkacik, M., Toia, A., Topilskaya, N., Toppi, M., Torales-Acosta, F., Tork, T., Torres, R. C., Torres, S. R., Trifir??, A., Tripathy, S., Tripathy, T., Trogolo, S., Trombetta, G., Trubnikov, V., Trzaska, W. H., Trzcinski, T. P., Trzeciak, B. A., Tumkin, A., Turrisi, R., Tveter, T. S., Ullaland, K., Uras, A., Urioni, M., Usai, G. L., Vala, M., Valle, N., Vallero, S., van der Kolk, N., van Doremalen, L. V. R., van Leeuwen, M., Vande Vyvre, P., Varga, D., Varga, Z., Varga-Kofarago, M., Vargas, A., Vasileiou, M., Vasiliev, A., V??zquez Doce, O., Vechernin, V., Vercellin, E., Vergara Lim??n, S., Vermunt, L., V??rtesi, R., Verweij, M., Vickovic, L., Vilakazi, Z., Villalobos Baillie, O., Vino, G., Vinogradov, A., Virgili, T., Vislavicius, V., Vodopyanov, A., Volkel, B., V??lkl, M. A., Voloshin, K., Voloshin, S. A., Volpe, G., von Haller, B., Vorobyev, I., Voscek, D., Vozniuk, N., Vrl??kov??, J., Wagner, B., Wang, C., Wang, D., Weber, M., Weelden, R. J. G. V., Wegrzynek, A., Wenzel, S. C., Wessels, J. P., Wiechula, J., Wikne, J., Wilk, G., Wilkinson, J., Willems, G. A., Windelband, B., Winn, M., Witt, W. E., Wright, J. R., Wu, W., Wu, Y., Xu, R., Yalcin, S., Yamaguchi, Y., Yamakawa, K., Yang, S., Yano, S., Yin, Z., Yokoyama, H., Yoo, I. -K., Yoon, J. H., Yuan, S., Yuncu, A., Zaccolo, V., Zaman, A., Zampolli, C., Zanoli, H. J. C., Zardoshti, N., Zarochentsev, A., Z??vada, P., Zaviyalov, N., Zbroszczyk, H., Zhalov, M., Zhang, S., Zhang, X., Zhang, Y., Zherebchevskii, V., Zhi, Y., Zhou, D., Zhou, Y., Zhu, J., Zhu, Y., Zichichi, A., Zinovjev, G., Zurlo, N., Laboratoire de physique subatomique et des technologies associées (SUBATECH), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), ALICE, Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Acharya S., Adamova D., Adler A., Adolfsson J., Aglieri Rinella G., Agnello M., Agrawal N., Ahammed Z., Ahmad S., Ahn S.U., Ahuja I., Akbar Z., Akindinov A., Al-Turany M., Alam S.N., Aleksandrov D., Alessandro B., Alfanda H.M., Alfaro Molina R., Ali B., Ali Y., Alici A., Alizadehvandchali N., Alkin A., Alme J., Alt T., Altenkamper L., Altsybeev I., Anaam M.N., Andrei C., Andreou D., Andronic A., Angeletti M., Anguelov V., Antinori F., Antonioli P., Anuj C., Apadula N., Aphecetche L., Appelshauser H., Arcelli S., Arnaldi R., Arsene I.C., Arslandok M., Augustinus A., Averbeck R., Aziz S., Azmi M.D., Badala A., Baek Y.W., Bai X., Bailhache R., Bailung Y., Bala R., Balbino A., Baldisseri A., Balis B., Ball M., Banerjee D., Barbera R., Barioglio L., Barlou M., Barnafoldi G.G., Barnby L.S., Barret V., Bartels C., Barth K., Bartsch E., Baruffaldi F., Bastid N., Basu S., Batigne G., Batyunya B., Bauri D., Bazo Alba J.L., Bearden I.G., Beattie C., Belikov I., Bell Hechavarria A.D.C., Bellini F., Bellwied R., Belokurova S., Belyaev V., Bencedi G., Beole S., Bercuci A., Berdnikov Y., Berdnikova A., Berenyi D., Bergmann L., Besoiu M.G., Betev L., Bhaduri P.P., Bhasin A., Bhat I.R., Bhat M.A., Bhattacharjee B., Bhattacharya P., Bianchi L., Bianchi N., Bielcik J., Bielcikova J., Biernat J., Bilandzic A., Biro G., Biswas S., Blair J.T., Blau D., Blidaru M.B., Blume C., Boca G., Bock F., Bogdanov A., Boi S., Bok J., Boldizsar L., Bolozdynya A., Bombara M., Bond P.M., Bonomi G., Borel H., Borissov A., Bossi H., Botta E., Bratrud L., Braun-Munzinger P., Bregant M., Broz M., Bruno G.E., Buckland M.D., Budnikov D., Buesching H., Bufalino S., Bugnon O., Buhler P., Buthelezi Z., Butt J.B., Bysiak S.A., Caffarri D., Cai M., Caines H., Caliva A., Calvo Villar E., Camacho J.M.M., Camacho R.S., Camerini P., Canedo F.D.M., Carnesecchi F., Caron R., Castillo Castellanos J., Casula E.A.R., Catalano F., Ceballos Sanchez C., Chakraborty P., Chandra S., Chapeland S., Chartier M., Chattopadhyay S., Chauvin A., Chavez T.G., Cheshkov C., Cheynis B., Chibante Barroso V., Chinellato D.D., Cho S., Chochula P., Christakoglou P., Christensen C.H., Christiansen P., Chujo T., Cicalo C., Cifarelli L., Cindolo F., Ciupek M.R., Clai G., Cleymans J., Colamaria F., Colburn J.S., Colella D., Collu A., Colocci M., Concas M., Conesa Balbastre G., Conesa del Valle Z., Contin G., Contreras J.G., Coquet M.L., Cormier T.M., Cortese P., Cosentino M.R., Costa F., Costanza S., Crochet P., Cuautle E., Cui P., Cunqueiro L., Dainese A., Damas F.P.A., Danisch M.C., Danu A., Das I., Das P., Das S., Dash S., De S., De Caro A., de Cataldo G., De Cilladi L., de Cuveland J., De Falco A., De Gruttola D., De Marco N., De Martin C., De Pasquale S., Deb S., Degenhardt H.F., Deja K.R., Dello Stritto L., Delsanto S., Deng W., Dhankher P., Di Bari D., Di Mauro A., Diaz R.A., Dietel T., Ding Y., Divia R., Dixit D.U., Djuvsland O., Dmitrieva U., Do J., Dobrin A., Donigus B., Dordic O., Dubey A.K., Dubla A., Dudi S., Dukhishyam M., Dupieux P., Dzalaiova N., Eder T.M., Ehlers R.J., Eikeland V.N., Elia D., Erazmus B., Ercolessi F., Erhardt F., Erokhin A., Ersdal M.R., Espagnon B., Eulisse G., Evans D., Evdokimov S., Fabbietti L., Faggin M., Faivre J., Fan F., Fantoni A., Fasel M., Fecchio P., Feliciello A., Feofilov G., Fernandez Tellez A., Ferrero A., Ferretti A., Feuillard V.J.G., Figiel J., Filchagin S., Finogeev D., Fionda F.M., Fiorenza G., Flor F., Flores A.N., Foertsch S., Foka P., Fokin S., Fragiacomo E., Frajna E., Fuchs U., Funicello N., Furget C., Furs A., Gaardhoje J.J., Gagliardi M., Gago A.M., Gal A., Galvan C.D., Ganoti P., Garabatos C., Garcia J.R.A., Garcia-Solis E., Garg K., Gargiulo C., Garibli A., Garner K., Gasik P., Gauger E.F., Gautam A., Gay Ducati M.B., Germain M., Ghosh J., Ghosh P., Ghosh S.K., Giacalone M., Gianotti P., Giubellino P., Giubilato P., Glaenzer A.M.C., Glassel P., Goh D.J.Q., Gonzalez V., Gonzalez-Trueba L.H., Gorbunov S., Gorgon M., Gorlich L., Gotovac S., Grabski V., Graczykowski L.K., Greiner L., Grelli A., Grigoras C., Grigoriev V., Grigoryan A., Grigoryan S., Groettvik O.S., Grosa F., Grosse-Oetringhaus J.F., Grosso R., Guardiano G.G., Guernane R., Guilbaud M., Gulbrandsen K., Gunji T., Gupta A., Gupta R., Guzman I.B., Guzman S.P., Gyulai L., Habib M.K., Hadjidakis C., Halimoglu G., Hamagaki H., Hamar G., Hamid M., Hannigan R., Haque M.R., Harlenderova A., Harris J.W., Harton A., Hasenbichler J.A., Hassan H., Hatzifotiadou D., Hauer P., Havener L.B., Hayashi S., Heckel S.T., Hellbar E., Helstrup H., Herman T., Hernandez E.G., Herrera Corral G., Herrmann F., Hetland K.F., Hillemanns H., Hills C., Hippolyte B., Hofman B., Hohlweger B., Honermann J., Hong G.H., Horak D., Hornung S., Horzyk A., Hosokawa R., Hristov P., Huang C., Hughes C., Huhn P., Humanic T.J., Hushnud H., Husova L.A., Hutson A., Hutter D., Iddon J.P., Ilkaev R., Ilyas H., Inaba M., Innocenti G.M., Ippolitov M., Isakov A., Islam M.S., Ivanov M., Ivanov V., Izucheev V., Jablonski M., Jacak B., Jacazio N., Jacobs P.M., Jadlovska S., Jadlovsky J., Jaelani S., Jahnke C., Jakubowska M.J., Janik M.A., Janson T., Jercic M., Jevons O., Jonas F., Jones P.G., Jowett J.M., Jung J., Jung M., Junique A., Jusko A., Kaewjai J., Kalinak P., Kalweit A., Kaplin V., Kar S., Karasu Uysal A., Karatovic D., Karavichev O., Karavicheva T., Karczmarczyk P., Karpechev E., Kazantsev A., Kebschull U., Keidel R., Keijdener D.L.D., Keil M., Ketzer B., Khabanova Z., Khan A.M., Khan S., Khanzadeev A., Kharlov Y., Khatun A., Khuntia A., Kileng B., Kim B., Kim D., Kim D.J., Kim E.J., Kim J., Kim J.S., Kim M., Kim S., Kim T., Kirsch S., Kisel I., Kiselev S., Kisiel A., Kitowski J.P., Klay J.L., Klein J., Klein S., Klein-Bosing C., Kleiner M., Klemenz T., Kluge A., Knospe A.G., Kobdaj C., Kohler M.K., Kollegger T., Kondratyev A., Kondratyeva N., Kondratyuk E., Konig J., Konigstorfer S.A., Konopka P.J., Kornakov G., Koryciak S.D., Koska L., Kotliarov A., Kovalenko O., Kovalenko V., Kowalski M., Kralik I., Kravcakova A., Kreis L., Krivda M., Krizek F., Krizkova Gajdosova K., Kroesen M., Kruger M., Kryshen E., Krzewicki M., Kucera V., Kuhn C., Kuijer P.G., Kumaoka T., Kumar D., Kumar L., Kumar N., Kundu S., Kurashvili P., Kurepin A., Kurepin A.B., Kuryakin A., Kushpil S., Kvapil J., Kweon M.J., Kwon J.Y., Kwon Y., La Pointe S.L., La Rocca P., Lai Y.S., Lakrathok A., Lamanna M., Langoy R., Lapidus K., Larionov P., Laudi E., Lautner L., Lavicka R., Lazareva T., Lea R., Lee J., Lehrbach J., Lemmon R.C., Leon Monzon I., Lesser E.D., Lettrich M., Levai P., Li X., Li X.L., Lien J., Lietava R., Lim B., Lim S.H., Lindenstruth V., Lindner A., Lippmann C., Liu A., Liu J., Lofnes I.M., Loginov V., Loizides C., Loncar P., Lopez J.A., Lopez X., Lopez Torres E., Luhder J.R., Lunardon M., Luparello G., Ma Y.G., Maevskaya A., Mager M., Mahmoud T., Maire A., Malaev M., Malik Q.W., Malinina L., Mal'Kevich D., Mallick N., Malzacher P., Mandaglio G., Manko V., Manso F., Manzari V., Mao Y., Mares J., Margagliotti G.V., Margotti A., Marin A., Markert C., Marquard M., Martin N.A., Martinengo P., Martinez J.L., Martinez M.I., Martinez Garcia G., Masciocchi S., Masera M., Masoni A., Massacrier L., Mastroserio A., Mathis A.M., Matonoha O., Matuoka P.F.T., Matyja A., Mayer C., Mazuecos A.L., Mazzaschi F., Mazzilli M., Mazzoni M.A., Mdhluli J.E., Mechler A.F., Meddi F., Melikyan Y., Menchaca-Rocha A., Meninno E., Menon A.S., Meres M., Mhlanga S., Miake Y., Micheletti L., Migliorin L.C., Mihaylov D.L., Mikhaylov K., Mishra A.N., Miskowiec D., Modak A., Mohanty A.P., Mohanty B., Mohisin Khan M., Moravcova Z., Mordasini C., Moreira De Godoy D.A., Moreno L.A.P., Morozov I., Morsch A., Mrnjavac T., Muccifora V., Mudnic E., Muhlheim D., Muhuri S., Mulligan J.D., Mulliri A., Munhoz M.G., Munzer R.H., Murakami H., Murray S., Musa L., Musinsky J., Myers C.J., Myrcha J.W., Naik B., Nair R., Nandi B.K., Nania R., Nappi E., Naru M.U., Nassirpour A.F., Nath A., Nattrass C., Neagu A., Nellen L., Nesbo S.V., Neskovic G., Nesterov D., Nielsen B.S., Nikolaev S., Nikulin S., Nikulin V., Noferini F., Noh S., Nomokonov P., Norman J., Novitzky N., Nowakowski P., Nyanin A., Nystrand J., Ogino M., Ohlson A., Okorokov V.A., Oleniacz J., Oliveira Da Silva A.C., Oliver M.H., Onnerstad A., Oppedisano C., Ortiz Velasquez A., Osako T., Oskarsson A., Otwinowski J., Oyama K., Pachmayer Y., Padhan S., Pagano D., Paic G., Palasciano A., Pan J., Panebianco S., Pareek P., Park J., Parkkila J.E., Pathak S.P., Patra R.N., Paul B., Pazzini J., Pei H., Peitzmann T., Peng X., Pereira L.G., Pereira Da Costa H., Peresunko D., Perez G.M., Perrin S., Pestov Y., Petracek V., Petrovici M., Pezzi R.P., Piano S., Pikna M., Pillot P., Pinazza O., Pinsky L., Pinto C., Pisano S., Ploskon M., Planinic M., Pliquett F., Poghosyan M.G., Polichtchouk B., Politano S., Poljak N., Pop A., Porteboeuf-Houssais S., Porter J., Pozdniakov V., Prasad S.K., Preghenella R., Prino F., Pruneau C.A., Pshenichnov I., Puccio M., Qiu S., Quaglia L., Quishpe R.E., Ragoni S., Rakotozafindrabe A., Ramello L., Rami F., Ramirez S.A.R., Ramos A.G.T., Rancien T.A., Raniwala R., Raniwala S., Rasanen S.S., Rath R., Ravasenga I., Read K.F., Redelbach A.R., Redlich K., Rehman A., Reichelt P., Reidt F., Reme-ness H.A., Renfordt R., Rescakova Z., Reygers K., Riabov A., Riabov V., Richert T., Richter M., Riegler W., Riggi F., Ristea C., Rode S.P., Rodriguez Cahuantzi M., Roed K., Rogalev R., Rogochaya E., Rogoschinski T.S., Rohr D., Rohrich D., Rojas P.F., Rokita P.S., Ronchetti F., Rosano A., Rosas E.D., Rossi A., Rotondi A., Roy A., Roy P., Roy S., Rubini N., Rueda O.V., Rui R., Rumyantsev B., Russek P.G., Rustamov A., Ryabinkin E., Ryabov Y., Rybicki A., Rytkonen H., Rzesa W., Saarimaki O.A.M., Sadek R., Sadovsky S., Saetre J., Safarik K., Saha S.K., Saha S., Sahoo B., Sahoo P., Sahoo R., Sahoo S., Sahu D., Sahu P.K., Saini J., Sakai S., Sambyal S., Samsonov V., Sarkar D., Sarkar N., Sarma P., Sarti V.M., Sas M.H.P., Schambach J., Scheid H.S., Schiaua C., Schicker R., Schmah A., Schmidt C., Schmidt H.R., Schmidt M.O., Schmidt M., Schmidt N.V., Schmier A.R., Schotter R., Schukraft J., Schutz Y., Schwarz K., Schweda K., Scioli G., Scomparin E., Seger J.E., Sekiguchi Y., Sekihata D., Selyuzhenkov I., Senyukov S., Seo J.J., Serebryakov D., Serksnyte L., Sevcenco A., Shaba T.J., Shabanov A., Shabetai A., Shahoyan R., Shaikh W., Shangaraev A., Sharma A., Sharma H., Sharma M., Sharma N., Sharma S., Sheibani O., Shigaki K., Shimomura M., Shirinkin S., Shou Q., Sibiriak Y., Siddhanta S., Siemiarczuk T., Silva T.F., Silvermyr D., Simonetti G., Singh B., Singh R., Singh V.K., Singhal V., Sinha T., Sitar B., Sitta M., Skaali T.B., Skorodumovs G., Slupecki M., Smirnov N., Snellings R.J.M., Soncco C., Song J., Songmoolnak A., Soramel F., Sorensen S., Sputowska I., Stachel J., Stan I., Steffanic P.J., Stiefelmaier S.F., Stocco D., Storehaug I., Storetvedt M.M., Stylianidis C.P., Suaide A.A.P., Sugitate T., Suire C., Suljic M., Sultanov R., Sumbera M., Sumberia V., Sumowidagdo S., Swain S., Szabo A., Szarka I., Tabassam U., Taghavi S.F., Taillepied G., Takahashi J., Tambave G.J., Tang S., Tang Z., Tarhini M., Tarzila M.G., Tauro A., Tejeda Munoz G., Telesca A., Terlizzi L., Terrevoli C., Tersimonov G., Thakur S., Thomas D., Tieulent R., Tikhonov A., Timmins A.R., Tkacik M., Toia A., Topilskaya N., Toppi M., Torales-Acosta F., Tork T., Torres R.C., Torres S.R., Trifiro A., Tripathy S., Tripathy T., Trogolo S., Trombetta G., Trubnikov V., Trzaska W.H., Trzcinski T.P., Trzeciak B.A., Tumkin A., Turrisi R., Tveter T.S., Ullaland K., Uras A., Urioni M., Usai G.L., Vala M., Valle N., Vallero S., van der Kolk N., van Doremalen L.V.R., van Leeuwen M., Vande Vyvre P., Varga D., Varga Z., Varga-Kofarago M., Vargas A., Vasileiou M., Vasiliev A., Vazquez Doce O., Vechernin V., Vercellin E., Vergara Limon S., Vermunt L., Vertesi R., Verweij M., Vickovic L., Vilakazi Z., Villalobos Baillie O., Vino G., Vinogradov A., Virgili T., Vislavicius V., Vodopyanov A., Volkel B., Volkl M.A., Voloshin K., Voloshin S.A., Volpe G., von Haller B., Vorobyev I., Voscek D., Vozniuk N., Vrlakova J., Wagner B., Wang C., Wang D., Weber M., Weelden R.J.G.V., Wegrzynek A., Wenzel S.C., Wessels J.P., Wiechula J., Wikne J., Wilk G., Wilkinson J., Willems G.A., Windelband B., Winn M., Witt W.E., Wright J.R., Wu W., Wu Y., Xu R., Yalcin S., Yamaguchi Y., Yamakawa K., Yang S., Yano S., Yin Z., Yokoyama H., Yoo I.-K., Yoon J.H., Yuan S., Yuncu A., Zaccolo V., Zaman A., Zampolli C., Zanoli H.J.C., Zardoshti N., Zarochentsev A., Zavada P., Zaviyalov N., Zbroszczyk H., Zhalov M., Zhang S., Zhang X., Zhang Y., Zherebchevskii V., Zhi Y., Zhou D., Zhou Y., Zhu J., Zhu Y., Zichichi A., Zinovjev G., and Zurlo N.
Subjects: atom: exotic, heavy ion: scattering, nucleon: pair, correlation [momentum], exotic, heavy ion, scattering, momentum, correlation, measurement methods, Hadron, 01 natural sciences, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), effective field theory, ALICE, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], effective field theory: chiral, Nuclear Experiment (nucl-ex), Nuclear Experiment, chiral [effective field theory], effective field theory, chiral, Physics, atom, exotic, SPECTROSCOPY, atom, strong interaction, nucleon, two-particle, heavy ion, 3. Good health, CERN LHC Coll, kinematics, force, Coulomb, Scattering theory, Nucleon, force, Coulomb [force], Particle Physics - Experiment, Particle physics, Nuclear and High Energy Physics, strong interaction [K p], QC1-999, FOS: Physical sciences, momentum, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], K p: strong interaction, momentum: correlation, force: Coulomb, nucleon, pair, sensitivity, TeV, scattering length, experimental results, 5020 GeV-cms/nucleon, hadron, 114 Physical sciences, scattering [heavy ion], 0103 physical sciences, SCATTERING, Nuclear Physics - Experiment, ddc:530, Sensitivity (control systems), 010306 general physics, exotic [atom], Exotic atom, 010308 nuclear & particles physics, Scattering, pair, pair [nucleon], Scattering length, Heavy Ions Experiments, LOW-ENERGY K, DA-PHI-NE, chiral, ALICE, heavy-ion collisions, nuclear physics, correlation, Coulomb, High Energy Physics::Experiment, Energy (signal processing)
Abstract: Physics letters / B 822, 136708 (2021). doi:10.1016/j.physletb.2021.136708, In quantum scattering processes between two particles, aspects characterizing the strong and Coulomb forces can be observed in kinematic distributions of the particle pairs. The sensitivity to the interaction potential reaches a maximum at low relative momentum and vanishing distance between the two particles. Ultrarelativistic heavy-ion collisions at the LHC provide an abundant source of many hadron species and can be employed as a measurement method of scattering parameters that is complementary to scattering experiments. This study confirms that momentum correlations of particles produced in Pb��Pb collisions at the LHC provide an accurate measurement of kaon��proton scattering parameters at low relative momentum, allowing precise access to the $K^- p \to K^- p$ process. This work also validates the femtoscopic measurement in ultrarelativistic heavy-ion collisions as an alternative to scattering experiments and a complementary tool to the study of exotic atoms with comparable precision. In this work, the first femtoscopic measurement of momentum correlations of $K^- p(K^- \overline{p})$ and $K^+p(K^-\overline{p})$ pairs in Pb��Pb collisions at centre-of-mass energy per nucleon pair of $\sqrt{s_{NN}}$=5.02 TeV registered by the ALICE experiment is reported. The components of the $K^-p$ complex scattering length are extracted and found to be $\Re f_0=-0.91 \pm 0.03 \textrm{(stat)}^{+0.17}_{-0.03} \textrm{(syst)}$ and $\Im f_0=0.92 \pm 0.05 \textrm{(stat)}_{-0.33}^{+0.12} \textrm{(syst)}$. The results are compared with chiral effective field theory predictions as well as with existing data from dedicated scattering and exotic kaonic atom experiments., Published by North-Holland Publ., Amsterdam
Published: 2021

44. Repurposing Combination Therapy of Voacamine With Vincristine for Downregulation of Hypoxia-Inducible Factor-1α/Fatty Acid Synthase Co-axis and Prolyl Hydroxylase-2 Activation in ER+ Mammary Neoplasia

Author: Abdulaziz S. Saeedan, Gaurav Kaithwas, Lakhveer Singh, Mohd Nazam Ansari, Subhadeep Roy, Dinesh Kumar, Shubham Rastogi, Anurag Kumar, and Manjari Singh
Subjects: Programmed cell death, hypoxia inducible factor-1α (HIF-1α), Combination therapy, biology, QH301-705.5, Chemistry, repurposable drugs, voacamine, Cell Biology, fatty acid synthase (FASN), Blot, Fatty acid synthase, Cell and Developmental Biology, Downregulation and upregulation, Hypoxia-inducible factors, Apoptosis, Cancer cell, biology.protein, Cancer research, prolyl hydroxylase-2, mammary gland carcinoma, Biology (General), Developmental Biology, Original Research
Abstract: The current study investigated the role of combination therapy with voacamine and vincristine in preventing mammary gland carcinoma through prolyl hydroxylase-2 activation. Prolyl hydroxylase-2 activation leads to the downregulation of hypoxia-inducible factor-1α and fatty acid synthase. Overexpression of hypoxia-inducible factor-1α and fatty acid synthase has been previously reported in solid tumors of the mammary gland. After screening a battery of natural compounds similar to vincristine, voacamine was selected as a possible prolyl hydroxylase-2 activator, and its activity was evaluated using a 7,12-dimethylbenz[a]anthracene-induced rat model. The combination therapy was evaluated for cardiac toxicity using a hemodynamic profile. Angiogenic markers were evaluated by carmine staining. Monotherapy and combination therapy were also evaluated for liver and kidney toxicity using hematoxylin and eosin staining. The antioxidant potential was delineated using oxidative stress markers. The serum metabolomic profile was studied using NMR spectroscopy, and the disruption of fatty acids was evaluated using gas chromatography. Western blotting of proteins involved in hypoxic pathways was performed to decipher the action of therapy at the molecular level. Immunoblotting analysis validated that combination therapy has potential toss with prolyl hydroxylase-2 activity and thus initiates proteolytic degradation of hypoxia-inducible factor-1α and its consequent effects. Combination therapy also stimulated programmed cell death (apoptosis) in rapidly dividing cancer cells. The present study explored the role of voacamine inactivation of prolyl hydroxylase-2, which can decrease the overexpression of hypoxia-inducible factor-1α and fatty acid synthase in mammary gland carcinoma cells., Graphical Abstract Mechanism of VOA and VIN to inhibit fatty acid synthesis in DMBA-induced mammary gland carcinoma of albino Wistar rats. Hypoxia-activated HIF-1α enhances lactate acidosis in the tumor microenvironment, and dysregulated pH in the tumor microenvironment activates SREBP-1c and FASN expression to speed up the fatty acid synthesis required for plasma membrane synthesis in rapidly proliferating cells. VOA- and VIN-activated PHD-2 enhanced the proteolytic degradation of HIF, thus inhibiting fatty acid synthesis. HIF-1α, hypoxia-inducible factor-1α; SREBP-1c, sterol regulatory element-binding protein-1c; FASN, fatty acid synthesis; PHD-2, prolyl hydroxylase-2.
Published: 2021

45. Soft input soft output Kalman equalizer for MIMO frequency selective fading channels.

Author: Subhadeep Roy and Tolga M. Duman
Published: 2007
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46. Experimental Evidence for an Attractive p-φ Interaction

Author: Marian Krivda, Subhadeep Roy, Francesco Noferini, Grzegorz Andrzej Wilk, Matthias Richter, Ante Bilandzic, Lawrence Pinsky, Philippe Pillot, Swati Saha, Hiroki Yokoyama, Cynthia Marie Hadjidakis, Horst Sebastian Scheid, Sergey Kiselev, Natalia Kondratyeva, Mateusz Andrzej Ploskon, Kirill Voloshin, Filippo Costa, Baidyanath Sahoo, Shakeel Ahmad, Krzysztof Redlich, Mikhail Zhalov, Alwina Ruixin Liu, Anna Onnerstad, Suharyo Sumowidagdo, Yanchun Ding, Marta Urioni, Marian Ivanov, Sami Sakari Rasanen, Juan Manuel Mejia Camacho, Stefano Boi, Michal Broz, Mohamad Tarhini, Cristiane Jahnke, Andreas Morsch, Anastasia Berdnikova, Corey James Myers, Stefano Trogolo, Shingo Sakai, Alberto Rotondi, Thomas Klemenz, Catalin-Lucian Ristea, Vitaly Loginov, Vladimir Nikulin, Laura Helena Gonzalez Trueba, Ali Zaman, Giulia Clai, Vikash Sumberia, Jesus Ricardo Alvarado Garcia, Anders Nils Erik Oskarsson, Boris Hippolyte, Marco van Leeuwen, Marco Marquard, Patrick Simon Reichelt, Rosario Nania, Yongwook Baek, Lidia Maria Gorlich, Kenneth Francis Read, Zaida Conesa del Valle, Salvatore De Pasquale, Teodor Siemiarczuk, Peter Chochula, Partha Pratim Bhaduri, Christophe Pierre Suire, Felix Reidt, Patrick Huhn, Slavka Jadlovska, Stefania Bufalino, Song Zhang, Vivek Singh, Sandeep Dudi, G. Bencedi, Lorenzo de Cilladi, Vasco Miguel Chibante Barroso, Luca Barioglio, Brigitte Cheynis, Natasha Sharma, Neelkamal Mallick, Dimitra Andreou, Austin Vincent Harton, Ailec Bell Hechavarria, Vladimir Belyaev, Podist Kurashvili, Raghunath Sahoo, Valerie Ramillien Barret, Josephina Rae Wright, Feng Fan, Stefano Piano, Michael Rudolf Ciupek, Takuya Kumaoka, Aurora Diozcora Vargas Trevino, Martin Kroesen, Supriya Das, Artur Furs, Rafael Peretti Pezzi, Daniel Michael Muhlheim, Ketil Roeed, Grigorii Feofilov, Andrea Rossi, Gustavo Conesa Balbastre, Anselmo Margotti, Artem Isakov, Bernhard Franz Ketzer, Benjamin Donigus, Hugo Denis Antonio Pereira Da Costa, Javier Ernesto Castillo Castellanos, Sebastian Dominik Koryciak, Alexander Kluge, Jhuma Ghosh, Sabyasachi Siddhanta, Michael Lettrich, Subhasis Chattopadhyay, Christophe Furget, Paolo Giubellino, Pierre Vande Vyvre, Victor Jose Gaston Feuillard, Jean Willy Andre Cleymans, Volker Lindenstruth, Francesca Soramel, Pritam Chakraborty, Barbara Antonina Trzeciak, Vladislav Manko, Nicola Rubini, Nachiketa Sarkar, Oleg Karavichev, Jian Liu, Sebastien Perrin, Domenico Elia, Alberto Caliva, Henrique Jose Correia Zanoli, Zubayer Ahammed, Nicolas Schmidt, Dezso Varga, Alex Henri Jean Chauvin, Joyful Elma Mdhluli, Stefano Politano, Petra Loncar, D. De Gruttola, Giacomo Vito Margagliotti, Mihai Petrovici, Ara Grigoryan, Jeremy John Wilkinson, Pooja Pareek, Bernd Stefan Windelband, Varlen Grabski, Leticia Cunqueiro Mendez, Dimitar Lubomirov Mihaylov, Bong-Hwi Lim, Johan Alme, Luciano Ramello, Mike Henry Petrus Sas, Anju Bhasin, Daicui Zhou, Alla Maevskaya, Philippe Crochet, Jonatan Adolfsson, Gian Michele Innocenti, Jogender Saini, Christos Pliatskas Stylianidis, Mihaela Gabriela Besoiu, Miroslaw Jablonski, Alberica Toia, Magnus Mager, Ester Anna Rita Casula, Bushra Ali, Sarah Julie Porteboeuf, Maria Barlou, Manuel Colocci, Anatoly Tikhonov, Prottay Das, Tatsuya Chujo, Negin Alizadehvandchali, Gergoe Hamar, Lennart van Doremalen, C. Ceballos Sanchez, Alberto Masoni, Lukas Koska, Somnath Kar, Pietro Antonioli, Mohammad Asif Bhat, Alexander Vinogradov, Dukhishyam Mallick, Nicola Funicello, Andrea Ferrero, Gennady Zinovjev, Sadhana Dash, Christian Schmidt, Zebo Tang, Linda Vickovic, Alexandre Shabetai, Jiyeon Kwon, Antonio Ortiz Velasquez, A. Matyja, Janusz Oleniacz, Bernhard Skaali, Pengyao Cui, Nicole Alice Martin, Mirko Planinic, Luisa Cifarelli, Silvia Pisano, Zuzana Moravcova, S. T. Heckel, Qiye Shou, Sanjay K. Ghosh, Zuzana Jakubcinova, Aude Marie Camille Glaenzer, Nicolo Jacazio, Raquel Estefania Quishpe Quishpe, Luca Micheletti, Yury Ryabov, Ulrich Fuchs, Corrado Gargiulo, Abhi Modak, Fabian Pliquett, Mikolaj Krzewicki, Boris Polishchuk, Marielle Chartier, Despina Hatzifotiadou, Jasper Elias Parkkila, Vytautas Vislavicius, Thomas Peitzmann, Robert Helmut Munzer, Soren Pontoppidan Sorensen, Sanghoon Lim, Raffaele Grosso, Leo Clifford Greiner, Roman Rogalev, Prottoy Das, Miljenko Suljic, Alessandra Fantoni, Franco Meddi, Dmitry Aleksandrov, Pavel Larionov, Franck Manso, Alexandra Neagu, Sibaliso Mhlanga, Qasim Waheed Malik, Alexandru Bercuci, Nora De Marco, Youngil Kwon, Andrey Zarochentsev, Harald Appelshaeuser, Fernando Torales Acosta, Antonio Uras, Chinorat Kobdaj, Arianna Grisel Torres Ramos, Angela Badala, Ritsuya Hosokawa, Adrian Florin Mechler, Guillermo Mesa Perez, Georgijs Skorodumovs, Oleksandr Kovalenko, Dagmar Adamová, David Dobrigkeit Chinellato, Rahul Ramachandran Nair, Jacopo Pazzini, Christian Klein-Boesing, Omar Vazquez Rueda, Hartmut Hillemanns, Yue Shi Lai, Annalisa De Caro, Edgar Dominguez Rosas, Wadut Shaikh, Gokhan Halimoglu, Fabio Catalano, Stefania Beole, Theraa Tork, Lukas Nellen, David Olle Rickard Silvermyr, Martin Schmidt, Ionel Stan, Mohammed Hamid, Joonil Lee, Giuseppe Trombetta, Lukas Lautner, Dong Jo Kim, Raphaelle Marie Bailhache, Peter Martin Jacobs, Hadi Hassan, Elisa Meninno, Meike Charlotte Danisch, Matthew Daniel Buckland, Klaus Johannes Reygers, Dominik Voscek, Jon Christopher Wikne, Alessandro De Falco, Gioacchino Vino, Charles E. Hughes, Ramni Gupta, Anand Kumar Dubey, Alexander Szabo, Filip Krizek, Laszlo Boldizsar, Alexander Kurepin, Peter Christiansen, J. W. Harris, Seyed Farid Taghavi, Erin Frances Gauger, Vit Kucera, Premomoy Ghosh, Dmitry Mal Kevich, Paola Gianotti, Marie Germain, Thomas Michael Cormier, Sergey Sadovskiy, Thomas Humanic, Uzma Tabassam, Adela Kravcakova, Preeti Dhankher, Inayat Rasool Bhat, Sanchari Thakur, Francesca Bellini, James Philip Iddon, Laszlo Gyulai, Jaehyeon Do, Solangel Rojas Torres, Emily Jade Willsher, Branislav Sitar, Roelof Jan Gijs van Weelden, Yajun Mao, Xinye Peng, Michal Meres, Tiziano Virgili, Markus Fasel, Vito Manzari, Arvind Khuntia, Ermanno Vercellin, Jose Luis Bazo Alba, Marco Giacalone, Alexandre Alarcon Do Passo Suaide, Mario Kruger, Antonio Di Mauro, Federico Ronchetti, Mengke Cai, Lokesh Kumar, Hua Pei, Ahsan Mehmood Khan, Christian Lippmann, Viktor Riabov, Guido Alexander Willems, Barthelemy von Haller, Deepa Thomas, Silvia Masciocchi, Sidharth Kumar Prasad, Annalisa Mastroserio, Paula Fernanda Toledo Matuoka, Laura Brittany Havener, Maurice Louis Coquet, R. J. Ehlers, Przemyslaw Karczmarczyk, Suman Deb, Federico Antinori, Anisa Khatun, Iwona Anna Sputowska, Ophelie Bugnon, Kenta Shigaki, Ayben Karasu Uysal, Y. Yamaguchi, Alice Elisabeth Ohlson, Simone Ragoni, Jan Honermann, Ezra Douglas Lesser, Kjetil Ullaland, Alexander Vodopyanov, Sergey Shirinkin, Yoshini Bailung, Cindy Mordasini, Lars Bratrud, Jan Musinsky, Luis Gustavo Pereira, Andrey Erokhin, Thibaut Albert Rancien, Andrey Vasiliev, Maciej Slupecki, Jens Joergen Gaardhoeje, Piotr Jan Konopka, Ombretta Pinazza, Michal Sumbera, Peter Glassel, Francesca Ercolessi, Piotr Nowakowski, Alena Gromada, Kai Oliver Schweda, Robin Albert Andre Caron, Anik Gupta, Sukalyan Chattopadhyay, Marcello Lunardon, Silvia Delsanto, Enrico Scomparin, Justin Thomas Blair, James Declan Mulligan, Maya Hachiya Shimomura, Alexey Kurepin, Tebogo Joyce Shaba, Anton Jusko, Svetlana Belokurova, Francesco Riggi, Gianluigi Boca, Panagiota Foka, Alexandr Tumkin, Rajendra Nath Patra, Hushnud Hushnud, Stephan Friedrich Stiefelmaier, Geun Hee Hong, Tiago Fiorini da Silva, Serhiy Senyukov, Paulus Gerardus Kuijer, Emma Gonzalez Hernandez, Alessandro Ferretti, Johannes Lehrbach, Susanna Costanza, Irais Bautista Guzman, Vladimir Ivanov, Ji-Young Kim, Magnus Rentsch Ersdal, Paola La Rocca, Edmundo Javier Garcia-Solis, Giulio Eulisse, Kilian Eberhard Schwarz, Bartosz Balis, Dmitrii Nesterov, Francesca Carnesecchi, Tabea Maria Eder, Oliver Matonoha, Alexander Adler, Janet Elizabeth Seger, Alessandro Balbino, Sven Gotovac, Zabulon Vilakazi, Roman Lavicka, Barbara Ewa Erazmus, Florian Herrmann, Massimo Lamanna, Jungeol Kim, Joakim Nystrand, Ivan Kralik, Miroslav Pikna, Mario Sitta, Bernhard Hohlweger, Giacomo Contin, Arturo Alejandro Menchaca-Rocha, Beomkyu Kim, Andrea Dubla, Michelangelo Agnello, Sushanta Tripathy, Cristina Terrevoli, Werner Riegler, Anjaly Sasikumar Menon, Mattia Faggin, Orlando Villalobos Baillie, Jan Fiete Grosse-Oetringhaus, Yury Kharlov, Luciano Musa, Attiq Ur Rehman, Igor Altsybeev, Motoi Inaba, Jin Hee Yoon, Austin Robert Schmier, Davide Pagano, Jiri Mares, Antonin Maire, Zhi Yu, Jesus Guillermo Contreras Nuno, Amalia Pop, Jennifer Lynn Klay, Francesco Mazzaschi, Min Jung Kweon, Marek Bombara, Sanjib Muhuri, Milan Tkacik, Ranbir Singh, Marco Toppi, Ernst Hellbar, Edith Zinhle Buthelezi, Simon Voigt Nesbø, Andreas Michael Mathis, Dmitry Serebryakov, Nikola Poljak, Giuseppe Simonetti, Ivan Ravasenga, Ya Zhu, Amanda Nicole Flores, Alexander Akindinov, Satoshi Yano, Monika Varga-Kofarago, Nicole Apadula, Udo Wolfgang Kebschull, Gabriele Fiorenza, Pascal Dupieux, Andrea Dainese, Rachid Guernane, Meenakshi Sharma, Imrich Szarka, Minjung Kim, Nicole Bastid, Sergey Fokin, Katharina Demmich, Viljar Nilsen Eikeland, Torsten Alt, Chun-Lu Huang, Navneet Kumar, Petr Zavada, Debojit Sarkar, Antonio Palasciano, Michael Andreas Winn, Gerardo Antonio Herrera Corral, Vladimir Vechernin, Yasir Ali, Hermann Franz Degenhardt, Raul Arteche Diaz, Marta Verweij, Ralf Peter Averbeck, Laure Marie Massacrier, Malgorzata Anna Janik, Yifei Zhang, Jon-Are Saetre, Jeongsu Bok, Haidar Mas'Ud Alfanda, Daniel Berenyi, Rutuparna Rath, Christina Markert, Paolo Martinengo, Eugenio Nappi, Vladimir Izucheev, Sumit Basu, K. Krizkova Gajdosova, Matthias Kleiner, Marc Weber, Anthony Robert Timmins, Haakon Andre Reme-Ness, Adam Ryszard Kisiel, Tatiana Lazareva, Christian Holm Christensen, Jinjin Pan, Yury Melikyan, Jihye Song, Sarah Louise La Pointe, Germano Bonomi, Adrian Horzyk, Bedangadas Mohanty, Kristjan Herlache Gulbrandsen, David Karatovic, Saul Anibal Rodriguez Ramirez, Johannes Peter Wessels, S. R. Klein, Dmitry Yurevich Peresunko, Junlee Kim, Elisa Laudi, R Jefferson Porter, Guillermo Tejeda Munoz, Costin Grigoras, Nikolai Smirnov, Sheetal Sharma, Ida Storehaug, Michael Karim Habib, Jan Jadlovsky, Laura Serksnyte, Lucia Anna Husova, Raphael Noel Tieulent, Reynier Cruz Torres, Markus Ball, Przemyslaw Stefan Rokita, Evgeny Kryshen, Dhruv Utpalkumar Dixit, Gabriel Garcia Guardiano, Zoltán Varga, Ankhi Roy, Sebastian Adam Bysiak, Latchezar Betev, Roberto Preghenella, Taku Gunji, Francesco Prino, Alexander Schmah, Matteo Concas, Adrian Sevcenco, Alexey Bogdanov, Stefano Panebianco, Roy Crawford Lemmon, Lucas Altenkamper, Yitao Wu, Jun Takahashi, Jana Bielcikova, Robert Vertesi, Paul Alois Buhler, Aydan Garibli, Jens Wiechula, Bjarte Kileng, Kamil Rafal Deja, Peter Graham Jones, Smbat Grigoryan, Gvozden Neskovic, Darius Keijdener, Rainer Martin Schicker, Ernesto Lopez Torres, Bhawani Singh, Mihail Bogdan Blidaru, Antoine Jean-Simon Junique, Yasuo Miake, Sinjini Chandra, Jakub Kvapil, Ernesto Calvo Villar, Georgui Kornakov, Andre Augustinus, Vojtech Petracek, Debjani Banerjee, Fernando Antonio Flor, Davide Caffarri, Nicolo' Valle, Bharati Naik, Kirill Lapidus, Yury Pestov, Tariq Mahmoud, Sylvain Chapeland, Rinaldo Rui, Sergey Evdokimov, Ganesh Jagannath Tambave, Alberto Collu, Xiaoming Zhang, Henner Buesching, Carlos Duarte Galvan, Buddhadeb Bhattacharjee, Boris Wagner, Shinichi Hayashi, David H. Evans, Antonio Carlos Oliveira da Silva, Diego Stocco, Eugen Mudnic, Daniel Jia Qin Goh, Tonatiuh Garcia Chavez, Jamila Bashir Butt, Christian Claude Kuhn, Emma Sophia Chizzali, Shreyasi Acharya, Sergey Nikolaev, Constantinos Loizides, Ravindra Singh, Sagarika Swain, Hideki Hamagaki, Nikolay Zavyalov, Vladimir Zherebchevskii, Peter Kalinak, Marianna Mazzilli, Adriana Telesca, Patrick John Steffanic, Peter Matthew Bond, Ionut Cristian Arsene, Arturo Tauro, Soyeon Cho, A. Alkin, Florian Eisenhut, Antonio Trifiro, Auro Prasad Mohanty, Tim Sebastian Rogoschinski, Takumi Osako, Peter Braun-Munzinger, Sanjeev Singh Sambyal, A. Nath, Luis Alberto Perez Moreno, Valeriy Pozdniakov, Jacek Kitowski, Sean Murray, Lukas Kreis, Zaenal Akbar, Serpil Yalcin Kuzu, Alberto Martin Gago Medina, Ralf Keidel, Johann Joachim Schambach, Peter Levai, Fiorella Maria Celeste Fionda, Shi Qiu, Gergely Gabor Barnafoldi, Jacek Tomasz Otwinowski, Zhanna Khabanova, Adrian Fereydon Nassirpour, Sudhir Pandurang Rode, Georgy Tersimonov, Bas Hofman, Maria Vasileiou, Eun Joo Kim, Nicola Zurlo, Vladimir Kovalenko, Shiming Yang, Hira Ilyas, Sarita Sahoo, Giuseppe Mandaglio, Joshua Leon Konig, Christoph Mayer, Jens Robert Luhder, Claudiu Cornel Schiaua, Ishaan Ahuja, Filippo Baruffaldi, Sergey Filchagin, Marco Bregant, Oskari Antti Matti Saarimaki, Luisa Bergmann, Andrea Danu, Thomas Janson, Guillaume Batigne, Massimo Angeletti, Evgeny Karpechev, Tomasz Trzcinski, Pawel Grzegorz Russek, Xiaomei Li, Markus Keil, Renu Bala, Christoph Blume, Andrzej Rybicki, Kosei Yamakawa, Anar Rustamov, Esther Bartsch, Nima Zardoshti, Giacomo Volpe, Mikhail Ippolitov, Livia Terlizzi, Chunzheng Wang, Mauro Rogerio Cosentino, Jose Garabatos Cuadrado, Fabio Filippo Colamaria, Xiaozhi Bai, Haavard Helstrup, Giacinto de Cataldo, Anders Garritt Knospe, Tomas Herman, Amrit Gautam, Michael Henry Oliver, Laurent Bernard Aphecetche, Iouri Belikov, Thomas Dietel, Roman Lietava, Herve Borel, You Zhou, Bruno Alessandro, Alek Hutson, H. Caines, Sudhir Raniwala, Tatiana Karavicheva, Denise Aparecida Moreira De Godoy, Alexandru Florin Dobrin, Mario Rodriguez Cahuantzi, Sandro Christian Wenzel, Syaefudin Jaelani, Laura Fabbietti, Dibakar Bauri, Gines Martinez-Garcia, Grazia Luparello, Caitlin Beattie, Natalia Dzalaiova, Paraskevi Ganoti, Fabrizio Grosa, Eleazar Cuautle Flores, Victor Gonzalez, Silvia Arcelli, Randhir Singh, Raffaele del Grande, Dariusz Czeslaw Miskowiec, Lucas Anne Vermunt, Oton Vazquez Doce, Julian Wojciech Myrcha, Arthur Willem Jean Gal, Rainer Arno Ernst Renfordt, Jinsook Kim, Romain Schotter, Petr Nomokonov, David Horak, Rashmi Raniwala, Anantachai Lakrathok, Luca Quaglia, Sebastian Hornung, Claude Andre Pruneau, Roberto Barbera, Paolo Camerini, Elena Botta, Sergey Voloshin, Zhongbao Yin, Jerome Jung, Philip Hauer, Rabi Soto Camacho, Ana Maria Marin, Peter Zahariev Hristov, Ken Oyama, Himanshu Sharma, Artem Kotliarov, Wladyslaw Henryk Trzaska, Madalina-Gabriela Tarzila, Mesut Arslandok, Alexei Khanzadeev, Lukasz Kamil Graczykowski, Valentina Mantovani Sarti, Alexander Nyanin, Basanta Kumar Nandi, Rishat Sultanov, Kristin Fanebust Hetland, Svetlana Kushpil, Antonina Rosano, Dmitry Blau, Sergey Gorbunov, Yuko Sekiguchi, Boris Batyunya, Chiara de Martin, A. R. Redelbach, Shiming Yuan, Oveis Sheibani, Wioleta Rzesa, Rune Langøy, Roberta Arnaldi, Anuj Chandra, Maxime Guilbaud, Mario Ivan Martinez Hernandez, Rosario Turrisi, Wenjing Deng, Teo Mrnjavac, Tulika Tripathy, Evgeny Kondratyuk, Gilda Scioli, Pradip Kumar Roy, Sudipan De, Evgeny Ryabinkin, Guy Paic, Yury Sibiryak, Seoyoung Noh, Hikari Murakami, Jørgen André Lien, William Edward Witt, Aditya Nath Mishra, Roberto Divia, Luigi Dello Stritto, Adam Tadeusz Wegrzynek, Yvonne Chiara Pachmayer, Alessandro Feliciello, Se Yong Kim, Amelia Lindner, Dmitry Finogeev, Purba Bhattacharya, Mohd Danish Azmi, Peter Malzacher, Markus Konrad Kohler, Bruno Espagnon, Jetnipit Kaewjai, Pietro Cortese, Rita Sadek, Andrei Riabov, Sourav Kundu, Ola Slettevoll Groettvik, Oliver Thomas Jevons, Rene Bellwied, Florian Jonas, Liudmila Malinina, Sizar Aziz, Pragati Sahoo, Norbert Novitzky, Monika Joanna Jakubowska, Giulio Usai, Ramona Lea, Jonathan Samuel Colburn, Marten Ole Schmidt, Sergio Paisano Guzman, Chiara Pinto, D. H. Kim, Dirk Hutter, Gabor Biro, Arturo Fernandez Tellez, Sergio Vergara Limon, Kunal Garg, Maximiliano Puccio, Raimond Snellings, Alexander Borissov, Vladislav Grigoryev, Giuseppe Bruno, Jose Ruben Alfaro Molina, Igor Morozov, Nataliya Topilskaya, Stefan Kirsch, Sergey Nikulin, Ran Xu, Johanna Stachel, Livio Bianchi, Dongfang Wang, Jacek Bogumil Biernat, Alexander Bolozdynya, Konstantin Mikhaylov, Federico Cindolo, Oeystein Djuvsland, Cvetan Valeriev Cheshkov, Ildefonso Leon Monzon, Radiy Ilkaev, Surya Prakash Pathak, Shaista Khan, Fouad Rami, F. Bock, Deekshit Kumar, Dmitry Budnikov, Antonio Lafuente Mazuecos, Igor Pshenichnov, I. Das, M. Mohisin Khan, Borge Svane Nielsen, Ingrid Mckibben Lofnes, Jan Figiel, Alperen Yuncu, Klaus Barth, Tinku Sarkar Sinha, Vitaly Okorokov, Ivan Vorobyev, Jin Joo Seo, Alessandro Grelli, Naomi van der Kolk, Alberto Baldisseri, Fabio de Moraes Canedo, Siegfried Valentin Foertsch, Piotr Jan Gasik, Vikas Singhal, Antonino Zichichi, Jorge Andres Lopez Lopez, Guillaume Taillepied, Marcelo Gameiro Munhoz, Valeria Muccifora, David Michael Rohr, Vladimir Kaplin, Dieter Roehrich, Muhammad Umair Naru, Xing Long Li, Jaime Norman, Marek Kowalski, Artem Shangaraev, Nicola Bianchi, Mustafa Anaam, Marek Gorgon, Lee Stuart Barnby, Wenya Wu, Pradip Kumar Sahu, Piero Giubilato, Jan Anton Hasenbichler, Xavier Bernard Lopez, Jaroslav Bielcik, Ryan Patrick Hannigan, Elena Rogochaya, Enrico Fragiacomo, Jacobb Lee Martinez, Jaehyun Kim, In Kwon Yoo, Anton Andronic, Jochen Klein, Heidi Maria Rytkonen, Trine Spedstad Tveter, Gianluca Aglieri Rinella, Ivan Kisel, Yaroslav Berdnikov, Florian Paul Andre Damas, Neelima Agrawal, Corrado Cicalo, John Jowett, Pablo Fierro Rojas, Martino Gagliardi, Clara Bartels, D. Di Bari, Martin Vala, Taejun Kim, Lucrezia Camilla Migliorin, Rihan Haque, Arnon Songmoolnak, Saikat Biswas, Ian Gardner Bearden, Eszter Frajna, Daiki Sekihata, Andrea Alici, Alexey Kuryakin, Hannah Bossi, Andrey Kondratyev, Yves Roland Schutz, Cristian Andrei, Venelin Anguelov, Andry Malala Rakotozafindrabe, Tuva Ora Herenui Richert, Siyu Tang, Benedikt Volkel, Mikhail Malaev, Martin Poghosyan, Barbara Jacak, Alexander Philipp Kalweit, Uliana Dmitrieva, Michael Jung, Thorsten Sven Kollegger, Christopher Hills, Dushmanta Sahu, Domenico Colella, Martin Andreas Volkl, Vladimir Samsonov, Christine Nattrass, Carlos Soncco Meza, Mohammad Al-Turany, Sang Un Ahn, Valentina Zaccolo, Hans Rudolf Schmidt, Pranjal Sarma, Ilya Selyuzhenkov, Boris Rumyantsev, S. N. Alam, Pietro Fecchio, Panagiotis Christakoglou, Jonghan Park, Samsul Islam, Olja Dordic, Hanna Paulina Zbroszczyk, Toru Sugitate, Anjali Sharma, Chiara Oppedisano, Junjie Zhu, Filip Erhardt, Karel Safarik, Arseniy Shabanov, Stephan Alexander Konigstorfer, Jurgen Schukraft, Victor Trubnikov, Julien Faivre, Chiara Zampolli, Sara Vallero, Marko Jercic, Andrey Kazantsev, Sumit Kumar Saha, Jan de Cuveland, Sonali Padhan, Massimo Masera, Maksim Melnik Storetvedt, Alice Mulliri, Biswarup Paul, Alessandra Maria Mazzoni, Ruben Shahoyan, Yu-Gang Ma, Janka Vrlakova, Masanori Ogino, Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), ALICE, Helsinki Institute of Physics, Acharya, S, Adamová, D, Adler, A, Adolfsson, J, Aglieri Rinella, G, Agnello, M, Agrawal, N, Ahammed, Z, Ahmad, S, Ahn, S U, Ahuja, I, Akbar, Z, Akindinov, A, Al-Turany, M, Alam, S N, Aleksandrov, D, Alessandro, B, Alfanda, H M, Alfaro Molina, R, Ali, B, Ali, Y, Alici, A, Alizadehvandchali, N, Alkin, A, Alme, J, Alt, T, Altenkamper, L, Altsybeev, I, Anaam, M N, Andrei, C, Andreou, D, Andronic, A, Angeletti, M, Anguelov, V, Antinori, F, Antonioli, P, Anuj, C, Apadula, N, Aphecetche, L, Appelshäuser, H, Arcelli, S, Arnaldi, R, Arsene, I C, Arslandok, M, Augustinus, A, Averbeck, R, Aziz, S, Azmi, M D, Badalà, A, Baek, Y W, Bai, X, Bailhache, R, Bailung, Y, Bala, R, Balbino, A, Baldisseri, A, Balis, B, Ball, M, Banerjee, D, Barbera, R, Barioglio, L, Barlou, M, Barnaföldi, G G, Barnby, L S, Barret, V, Bartels, C, Barth, K, Bartsch, E, Baruffaldi, F, Bastid, N, Basu, S, Batigne, G, Batyunya, B, Bauri, D, Bazo Alba, J L, Bearden, I G, Beattie, C, Belikov, I, Bell Hechavarria, A D C, Bellini, F, Bellwied, R, Belokurova, S, Belyaev, V, Bencedi, G, Beole, S, Bercuci, A, Berdnikov, Y, Berdnikova, A, Berenyi, D, Bergmann, L, Besoiu, M G, Betev, L, Bhaduri, P P, Bhasin, A, Bhat, I R, Bhat, M A, Bhattacharjee, B, Bhattacharya, P, Bianchi, L, Bianchi, N, Bielčík, J, Bielčíková, J, Biernat, J, Bilandzic, A, Biro, G, Biswas, S, Blair, J T, Blau, D, Blidaru, M B, Blume, C, Boca, G, Bock, F, Bogdanov, A, Boi, S, Bok, J, Boldizsár, L, Bolozdynya, A, Bombara, M, Bond, P M, Bonomi, G, Borel, H, Borissov, A, Bossi, H, Botta, E, Bratrud, L, Braun-Munzinger, P, Bregant, M, Broz, M, Bruno, G E, Buckland, M D, Budnikov, D, Buesching, H, Bufalino, S, Bugnon, O, Buhler, P, Buthelezi, Z, Butt, J B, Bysiak, S A, Caffarri, D, Cai, M, Caines, H, Caliva, A, Calvo Villar, E, Camacho, J M M, Camacho, R S, Camerini, P, Canedo, F D M, Carnesecchi, F, Caron, R, Castillo Castellanos, J, Casula, E A R, Catalano, F, Ceballos Sanchez, C, Chakraborty, P, Chandra, S, Chapeland, S, Chartier, M, Chattopadhyay, S, Chauvin, A, Chavez, T G, Cheshkov, C, Cheynis, B, Chibante Barroso, V, Chinellato, D D, Chizzali, E S, Cho, S, Chochula, P, Christakoglou, P, Christensen, C H, Christiansen, P, Chujo, T, Cicalo, C, Cifarelli, L, Cindolo, F, Ciupek, M R, Clai, G, Cleymans, J, Colamaria, F, Colburn, J S, Colella, D, Collu, A, Colocci, M, Concas, M, Conesa Balbastre, G, Conesa Del Valle, Z, Contin, G, Contreras, J G, Coquet, M L, Cormier, T M, Cortese, P, Cosentino, M R, Costa, F, Costanza, S, Crochet, P, Cuautle, E, Cui, P, Cunqueiro, L, Dainese, A, Damas, F P A, Danisch, M C, Danu, A, Das, I, Das, P, Das, S, Dash, S, De, S, De Caro, A, de Cataldo, G, De Cilladi, L, de Cuveland, J, De Falco, A, De Gruttola, D, De Marco, N, De Martin, C, De Pasquale, S, Deb, S, Degenhardt, H F, Deja, K R, Del Grande, R, Dello Stritto, L, Delsanto, S, Deng, W, Dhankher, P, Di Bari, D, Di Mauro, A, Diaz, R A, Dietel, T, Ding, Y, Divià, R, Dixit, D U, Djuvsland, Ø, Dmitrieva, U, Do, J, Dobrin, A, Dönigus, B, Dordic, O, Dubey, A K, Dubla, A, Dudi, S, Dukhishyam, M, Dupieux, P, Dzalaiova, N, Eder, T M, Ehlers, R J, Eikeland, V N, Eisenhut, F, Elia, D, Erazmus, B, Ercolessi, F, Erhardt, F, Erokhin, A, Ersdal, M R, Espagnon, B, Eulisse, G, Evans, D, Evdokimov, S, Fabbietti, L, Faggin, M, Faivre, J, Fan, F, Fantoni, A, Fasel, M, Fecchio, P, Feliciello, A, Feofilov, G, Fernández Téllez, A, Ferrero, A, Ferretti, A, Feuillard, V J G, Figiel, J, Filchagin, S, Finogeev, D, Fionda, F M, Fiorenza, G, Flor, F, Flores, A N, Foertsch, S, Foka, P, Fokin, S, Fragiacomo, E, Frajna, E, Fuchs, U, Funicello, N, Furget, C, Furs, A, Gaardhøje, J J, Gagliardi, M, Gago, A M, Gal, A, Galvan, C D, Ganoti, P, Garabatos, C, Garcia, J R A, Garcia-Solis, E, Garg, K, Gargiulo, C, Garibli, A, Garner, K, Gasik, P, Gauger, E F, Gautam, A, Gay Ducati, M B, Germain, M, Ghosh, J, Ghosh, P, Ghosh, S K, Giacalone, M, Gianotti, P, Giubellino, P, Giubilato, P, Glaenzer, A M C, Glässel, P, Goh, D J Q, Gonzalez, V, González-Trueba, L H, Gorbunov, S, Gorgon, M, Görlich, L, Gotovac, S, Grabski, V, Graczykowski, L K, Greiner, L, Grelli, A, Grigoras, C, Grigoriev, V, Grigoryan, A, Grigoryan, S, Groettvik, O S, Grosa, F, Grosse-Oetringhaus, J F, Grosso, R, Guardiano, G G, Guernane, R, Guilbaud, M, Gulbrandsen, K, Gunji, T, Gupta, A, Gupta, R, Guzman, I B, Guzman, S P, Gyulai, L, Habib, M K, Hadjidakis, C, Halimoglu, G, Hamagaki, H, Hamar, G, Hamid, M, Hannigan, R, Haque, M R, Harlenderova, A, Harris, J W, Harton, A, Hasenbichler, J A, Hassan, H, Hatzifotiadou, D, Hauer, P, Havener, L B, Hayashi, S, Heckel, S T, Hellbär, E, Helstrup, H, Herman, T, Hernandez, E G, Herrera Corral, G, Herrmann, F, Hetland, K F, Hillemanns, H, Hills, C, Hippolyte, B, Hofman, B, Hohlweger, B, Honermann, J, Hong, G H, Horak, D, Hornung, S, Horzyk, A, Hosokawa, R, Hristov, P, Huang, C, Hughes, C, Huhn, P, Humanic, T J, Hushnud, H, Husova, L A, Hutson, A, Hutter, D, Iddon, J P, Ilkaev, R, Ilyas, H, Inaba, M, Innocenti, G M, Ippolitov, M, Isakov, A, Islam, M S, Ivanov, M, Ivanov, V, Izucheev, V, Jablonski, M, Jacak, B, Jacazio, N, Jacobs, P M, Jadlovska, S, Jadlovsky, J, Jaelani, S, Jahnke, C, Jakubowska, M J, Janik, M A, Janson, T, Jercic, M, Jevons, O, Jonas, F, Jones, P G, Jowett, J M, Jung, J, Jung, M, Junique, A, Jusko, A, Kaewjai, J, Kalinak, P, Kalweit, A, Kaplin, V, Kar, S, Karasu Uysal, A, Karatovic, D, Karavichev, O, Karavicheva, T, Karczmarczyk, P, Karpechev, E, Kazantsev, A, Kebschull, U, Keidel, R, Keijdener, D L D, Keil, M, Ketzer, B, Khabanova, Z, Khan, A M, Khan, S, Khanzadeev, A, Kharlov, Y, Khatun, A, Khuntia, A, Kileng, B, Kim, B, Kim, D, Kim, D J, Kim, E J, Kim, J, Kim, J S, Kim, M, Kim, S, Kim, T, Kirsch, S, Kisel, I, Kiselev, S, Kisiel, A, Kitowski, J P, Klay, J L, Klein, J, Klein, S, Klein-Bösing, C, Kleiner, M, Klemenz, T, Kluge, A, Knospe, A G, Kobdaj, C, Köhler, M K, Kollegger, T, Kondratyev, A, Kondratyeva, N, Kondratyuk, E, Konig, J, Konigstorfer, S A, Konopka, P J, Kornakov, G, Koryciak, S D, Koska, L, Kotliarov, A, Kovalenko, O, Kovalenko, V, Kowalski, M, Králik, I, Kravčáková, A, Kreis, L, Krivda, M, Krizek, F, Krizkova Gajdosova, K, Kroesen, M, Krüger, M, Kryshen, E, Krzewicki, M, Kučera, V, Kuhn, C, Kuijer, P G, Kumaoka, T, Kumar, D, Kumar, L, Kumar, N, Kundu, S, Kurashvili, P, Kurepin, A, Kurepin, A B, Kuryakin, A, Kushpil, S, Kvapil, J, Kweon, M J, Kwon, J Y, Kwon, Y, La Pointe, S L, La Rocca, P, Lai, Y S, Lakrathok, A, Lamanna, M, Langoy, R, Lapidus, K, Larionov, P, Laudi, E, Lautner, L, Lavicka, R, Lazareva, T, Lea, R, Lee, J, Lehrbach, J, Lemmon, R C, León Monzón, I, Lesser, E D, Lettrich, M, Lévai, P, Li, X, Li, X L, Lien, J, Lietava, R, Lim, B, Lim, S H, Lindenstruth, V, Lindner, A, Lippmann, C, Liu, A, Liu, J, Lofnes, I M, Loginov, V, Loizides, C, Loncar, P, Lopez, J A, Lopez, X, López Torres, E, Luhder, J R, Lunardon, M, Luparello, G, Ma, Y G, Maevskaya, A, Mager, M, Mahmoud, T, Maire, A, Malaev, M, Malik, Q W, Malinina, L, Mal'Kevich, D, Mallick, N, Malzacher, P, Mandaglio, G, Manko, V, Manso, F, Manzari, V, Mao, Y, Mareš, J, Margagliotti, G V, Margotti, A, Marín, A, Markert, C, Marquard, M, Martin, N A, Martinengo, P, Martinez, J L, Martínez, M I, Martínez García, G, Masciocchi, S, Masera, M, Masoni, A, Massacrier, L, Mastroserio, A, Mathis, A M, Matonoha, O, Matuoka, P F T, Matyja, A, Mayer, C, Mazuecos, A L, Mazzaschi, F, Mazzilli, M, Mazzoni, M A, Mdhluli, J E, Mechler, A F, Meddi, F, Melikyan, Y, 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Subjects: Kjerne- og elementærpartikkelfysikk: 431 [VDP], Proton, General Physics and Astronomy, 01 natural sciences, High Energy Physics - Experiment, ALICE, scattering [p p], [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], correlation function, Nuclear Experiment, Physics, strong interaction, VDP::Kjerne- og elementærpartikkelfysikk: 431, Nuclear and elementary particle physics: 431 [VDP], VDP::Nuclear and elementary particle physics: 431, nuclear matter, PHOTOPRODUCTION, Particle Physics - Experiment, correlation: two-particle, QCD SUM-RULES, VECTOR-MESONS, COLLISIONS, PARTICLES, Particle physics, p p: scattering, Meson, Strong interaction, Correlation function (quantum field theory), [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Physics and Astronomy(all), 114 Physical sciences, symmetry: chiral, 0103 physical sciences, scattering length, Phi(1020), coupling constant, effective range, experimental results, 13000 GeV-cms/nucleon, Nuclear Physics - Experiment, ddc:530, phi meson, particle physics, ALICE, 010306 general physics, two-particle [correlation], Coupling constant, chiral [symmetry], 010308 nuclear & particles physics, Scattering, Scattering length, Nuclear matter, Strong Interaction, High Energy Physics::Experiment
Abstract: Physical review letters 127(17), 172301 (2021). doi:10.1103/PhysRevLett.127.172301, This Letter presents the first experimental evidence of the attractive strong interaction between a proton and a �� meson. The result is obtained from two-particle correlations of combined $p$-�� $\bar{p}$-�� pairs measured in high-multiplicity pp collisions at $\sqrt{s}$ = 13 TeV by the ALICE Collaboration. The spin-averaged scattering length and effective range of the p-�� interaction are extracted from the fully corrected correlation function employing the Lednick��-Lyuboshits approach. In particular, the imaginary part of the scattering length vanishes within uncertainties, indicating that inelastic processes do not play a prominent role for the p-�� interaction. These data demonstrate that the interaction is dominated by elastic p-�� scattering. Furthermore, an analysis employing phenomenological Gaussian- and Yukawa-type potentials is conducted. Under the assumption of the latter, the N-�� coupling constant is found to be $g_{N-��}$ = 0.14 �� 0.03(stat) �� 0.02(syst). This work provides valuable experimental input to accomplish a self-consistent description of the N-�� interaction, which is particularly relevant for the more fundamental studies on partial restoration of chiral symmetry in nuclear medium., Published by APS, College Park, Md.
Published: 2021

47. The Co-Moving Velocity in Immiscible Two-Phase Flow in Porous Media

Author: Subhadeep Roy, Håkon Pedersen, Santanu Sinha, and Alex Hansen
Subjects: Physics::Fluid Dynamics, General Chemical Engineering, Fluid Dynamics (physics.flu-dyn), FOS: Physical sciences, Physics - Fluid Dynamics, Catalysis
Abstract: We present a continuum (i.e., an effective) description of immiscible two-phase flow in porous media characterized by two fields, the pressure and the saturation. Gradients in these two fields are the driving forces that move the immiscible fluids around. The fluids are characterized by two seepage velocity fields, one for each fluid. Following Hansen et al.\ (Transport in Porous Media, 125, 565 (2018)), we construct a two-way transformation between the velocity couple consisting of the seepage velocity of each fluid, to a velocity couple consisting of the average seepage velocity of both fluids and a new velocity parameter, the co-moving velocity. The co-moving velocity is related but not equal to velocity difference between the two immiscible fluids. The two-way mapping, the mass conservation equation and the constitutive equations for the average seepage velocity and the co-moving velocity form a closed set of equations that determine the flow. There is growing experimental, computational and theoretical evidence that constitutive equation for the average seepage velocity has the form of a power law in the pressure gradient over a wide range of capillary numbers. Through the transformation between the two velocity couples, this constitutive equation may be taken directly into account in the equations describing the flow of each fluid. This is e.g., not possible using relative permeability theory. By reverse engineering relative permeability data from the literature, we construct the constitutive equation for the co-moving velocity. We also calculate the co-moving constitutive equation using a dynamic pore network model over a wide range of parameters, from where the flow is viscosity dominated to where the capillary and viscous forces compete., 29 pages, 18 figures
Published: 2021

48. K$^{0}_{\rm S}$- and (anti-)$\Lambda$-hadron correlations in pp collisions at $\sqrt{s} = 13$ TeV

Author: A. Harlenderova, Neelima Agrawal, M. S. Islam, Abhi Modak, John Jowett, D. Mal'Kevich, S. T. Heckel, Robert Helmut Munzer, Vladimir Zherebchevskii, Rosario Nania, Rahul Ramachandran Nair, Aleksey M. Tikhonov, Xinye Peng, Mengke Cai, O. Villalobos Baillie, Christian Lippmann, Luis Gustavo Pereira, M. Bombara, Peter Kalinak, Gokhan Halimoglu, Yu. V. Kharlov, P. F. T. Matuoka, Ulrich Fuchs, Corrado Gargiulo, Martino Gagliardi, Clara Bartels, Roman Rogalev, Prottoy Das, Omar Vazquez Rueda, Andrey Erokhin, Thibaut Albert Rancien, Neelkamal Mallick, Marianna Mazzilli, Adriana Telesca, Patrick John Steffanic, Dimitra Andreou, Austin Vincent Harton, Alexander Szabo, Filip Krizek, D. Di Bari, Andrey Vasiliev, Yue Shi Lai, Cindy Mordasini, Marie Germain, Erin Frances Gauger, C. J. Schmidt, Vit Kucera, Premomoy Ghosh, Maurice Louis Coquet, Konstantin Mikhaylov, Adela Kravcakova, Branislav Sitar, Enrico Scomparin, R. J. Ehlers, Anisa Khatun, Sidharth Kumar Prasad, Iwona Anna Sputowska, Annalisa Mastroserio, D. Evans, Anik Gupta, Emma Gonzalez Hernandez, Alessandro Ferretti, Peter Matthew Bond, Ionut Cristian Arsene, Preeti Dhankher, Johannes Lehrbach, W. Deng, Guido Alexander Willems, Kjetil Ullaland, N. De Marco, Paolo Giubellino, Y. Zhi, Purushottam Chakraborty, J. Porter, Stefano Piano, R. Cruz-Torres, Attiq Ur Rehman, Janet Elizabeth Seger, Philippe Crochet, Jochen Klein, Lars Bratrud, Francesco Riggi, Trine Spedstad Tveter, Ivan Kisel, Alexander Adler, Alessandro Balbino, Motoi Inaba, Jin Hee Yoon, Alice Elisabeth Ohlson, Jan Honermann, Panagiota Foka, Arturo Tauro, Soyeon Cho, A. Alkin, Florian Eisenhut, Lukas Lautner, Bernhard Hohlweger, Manuel Colocci, E. López Torres, Ezra Douglas Lesser, Alexander Vodopyanov, Yoshini Bailung, Michael Rudolf Ciupek, Antonio Trifiro, Victor Jose Gaston Feuillard, X. L. Li, Dmitrii Nesterov, Francesca Carnesecchi, Florian Herrmann, Massimo Lamanna, Raphaelle Marie Bailhache, Tabea Maria Eder, Werner Riegler, Shengkun Zhang, Alexandr Tumkin, Geun Hee Hong, Tiago Fiorini da Silva, Andrey Zarochentsev, Ermanno Vercellin, C. Ceballos Sanchez, Pablo Fierro Rojas, Anju Bhasin, T.H. Kim, Sanjib Muhuri, P. Roy, Marco Toppi, Alexander Kluge, E. Fragiacomo, Tatiana Lazareva, Ian Gardner Bearden, Eszter Frajna, Daiki Sekihata, Christian Holm Christensen, Germano Bonomi, Chong Kim, Vitaly Okorokov, Peter Chochula, Ivan Vorobyev, Jan Jadlovsky, S. Saha, Petr Zavada, Christina Markert, Przemyslaw Stefan Rokita, Silvia Arcelli, Pietro Fecchio, C. Hadjidakis, E. Nappi, Susan L. Swain, Lucas Altenkamper, Partha Pratim Bhaduri, Christophe Pierre Suire, Mukesh Sharma, Jian Liu, G. V. Margagliotti, Oliver Matonoha, Sushanta Tripathy, Cristina Terrevoli, G. A. Feofilov, Somnath Kar, Nicola Funicello, V. Samsonov, Aude Marie Camille Glaenzer, R. Alfaro Molina, Hadi Hassan, M. Masera, Yingchun Zhu, K. Šafařík, M. Zhalov, Andrea Ferrero, Alexey Kuryakin, Hannah Bossi, Jin Joo Seo, Alessandro Grelli, Dhruv Utpalkumar Dixit, Sebastien Perrin, A. Rakotozafindrabe, Zubayer Ahammed, Tebogo Joyce Shaba, Panagiotis Christakoglou, Lucrezia Camilla Migliorin, Gabriel Garcia Guardiano, Eugen Mudnic, Siegfried Valentin Foertsch, Xuan Zhang, Boris Batyunya, Shiming Yuan, Peter Glassel, Daniel Jia Qin Goh, Ionel Stan, Francesca Ercolessi, Vladimir Belyaev, J. T. Blair, Silvia Delsanto, Eleazar Cuautle, Tuva Ora Herenui Richert, Romain Schotter, Marielle Chartier, V. Grigoriev, Siyu Tang, Dagmar Adamová, Sandeep Dudi, G. Bencedi, Mohammed Hamid, Meike Charlotte Danisch, Paolo Camerini, Sergey Voloshin, Fabian Pliquett, Mikolaj Krzewicki, Raffaele Grosso, Benedikt Volkel, Alexander Akindinov, Antonio Palasciano, G. Hamar, Olja Dordic, Tonatiuh Garcia Chavez, J. Castillo Castellanos, Jamila Bashir Butt, Bhawani Singh, Mihail Bogdan Blidaru, Antoine Jean-Simon Junique, Philippe Pillot, Baidyanath Sahoo, Oleg Karavichev, Y. Sibiriak, Francesco Mazzaschi, Upasana Sharma, Ilya Selyuzhenkov, Marco Giacalone, Johan Alme, S. De Pasquale, Joakim Nystrand, Mikhail Malaev, D. Miśkowiec, Jihye Song, T. P. Sinha, Tomas Herman, Muhammad Umair Naru, Luciano Ramello, Evgeny Ryabinkin, Yasuo Miake, Sinjini Chandra, Miljenko Suljic, Jaehyeon Do, Solangel Rojas Torres, Toralf Bernhard Skaali, Anastasia Berdnikova, J. W. Harris, Seyed Farid Taghavi, A. Karasu Uysal, A. B. Kurepin, Jinjin Pan, Toru Sugitate, Xing Long Li, Jaime Norman, Christian Claude Kuhn, N. van der Kolk, Sumit Kumar Saha, Debjani Banerjee, Stefano Trogolo, Mario Kruger, Federico Ronchetti, Amrit Gautam, Nicola Bianchi, Shreyasi Acharya, H. Appelshäuser, Ketil Røed, Supriya Das, Artur Furs, Y. F. Ryabov, Adrian Liu, Vladislav Manko, Sergey Nikolaev, Fernando Antonio Flor, A. Ortiz Velasquez, Tatsuya Chujo, Mattia Faggin, Luciano Musa, Shafiq Ahmad, D. Budnikov, Yudi Ma, Peter Zahariev Hristov, Michael Henry Oliver, A. Feliciello, Patrick Simon Reichelt, Amelia Lindner, Nicola Rubini, Mustafa Anaam, Dmitry Finogeev, C. De Martin, F. Torales-Acosta, G. Martínez García, Milan Tkacik, Nikolai Smirnov, Ken Oyama, Rafael Peretti Pezzi, Himanshu Sharma, Martin Poghosyan, J. L. Klay, A. Rustamov, H. Borel, Federico Cindolo, K. Schweda, Silvia Masciocchi, Nicolo' Valle, Barbara Jacak, Alexander Philipp Kalweit, Raphael Noel Tieulent, Uliana Dmitrieva, M. V. Ivanov, Marek Gorgon, Wenya Wu, Przemyslaw Karczmarczyk, Markus Ball, Constantinos Loizides, Pradip Kumar Sahu, Suman Deb, Federico Antinori, Piero Giubilato, Bushra Ali, Q. Y. Shou, Maria Barlou, J. G. Contreras, Luca Barioglio, Brigitte Cheynis, Ophelie Bugnon, Jan Anton Hasenbichler, Xavier Bernard Lopez, Jaroslav Bielcik, Ryan Patrick Hannigan, Jan Musinsky, L. Dello Stritto, Roy Crawford Lemmon, Hideki Hamagaki, Petra Loncar, Jana Bielcikova, F. Bock, Deekshit Kumar, Amanda Nicole Flores, Ombretta Pinazza, Piotr Nowakowski, Michael Jung, Robert Vertesi, Mauro Rogerio Cosentino, Motomi Oya, I. K. Yoo, Lukas Koska, Negin Alizadehvandchali, Rene Bellwied, Elena Rogochaya, Florian Jonas, Takumi Osako, Bruno Alessandro, Alek Hutson, H. Caines, Sudhir Raniwala, Kenta Shigaki, S. Sadovsky, Christopher Hills, Dushmanta Sahu, Domenico Colella, Bjarte Kileng, M. Winn, L. De Cilladi, P. G. Kuijer, Artem Kotliarov, Madalina-Gabriela Tarzila, Antonio Lafuente Mazuecos, Svetlana Belokurova, C. Klein-Bösing, Martin Andreas Volkl, Alla Maevskaya, M. Mohisin Khan, Borge Svane Nielsen, Christine Nattrass, Francesco Noferini, B. Ketzer, Filip Erhardt, Jacobb Lee Martinez, Sean Murray, T. Kollegger, Hiroki Yokoyama, M. I. Martínez, Stephan Friedrich Stiefelmaier, A. S. Nyanin, F. Bellini, Marta Verweij, Giulio Eulisse, Anton Andronic, Alexandre Shabetai, Jiyeon Kwon, L. S. Pinsky, Alexander Bolozdynya, Mirko Planinic, J. L. Bazo Alba, Tatiana Karavicheva, Kamil Rafal Deja, Anna Onnerstad, Pragati Sahoo, Jeremy John Wilkinson, Fiorella Maria Celeste Fionda, Monika Joanna Jakubowska, Christophe Furget, Arseniy Shabanov, Kilian Eberhard Schwarz, Anselmo Margotti, Zebo Tang, Vladimir Izucheev, Jean Willy Andre Cleymans, Volker Lindenstruth, Linda Vickovic, Nicolo Jacazio, Alexander Borissov, Tiantian Cheng, Krzysztof Redlich, Yanchun Ding, Peter Graham Jones, David Michael Rohr, Artem Shangaraev, Barbara Antonina Trzeciak, Stephan Alexander Konigstorfer, Ritsuya Hosokawa, Smbat Grigoryan, Agneta Oskarsson, Katharina Garner, S. Sharma, Heidi Maria Rytkonen, Wenda Guo, Gvozden Neskovic, Kirill Voloshin, Rainer Martin Schicker, Sang Un Ahn, Valentina Zaccolo, Sandro Christian Wenzel, Eunja Kim, A. Matyja, Fabio Filippo Colamaria, F. Soramel, Thomas Klemenz, Y. Pestov, Edgar Dominguez Rosas, Felix Reidt, Julian Wojciech Myrcha, Dirk Hutter, Xiaozhi Bai, Arthur Willem Jean Gal, Rainer Arno Ernst Renfordt, Janusz Oleniacz, A. De Caro, M. Rodríguez Cahuantzi, M. J. Kweon, Y. Berdnikov, Ana Vargas, P. La Rocca, Masanori Ogino, D. L. Mihaylov, Kunal Garg, Maximiliano Puccio, Marian Krivda, Hans Rudolf Schmidt, Raimond Snellings, Sami Sakari Rasanen, Leo Clifford Greiner, Alberto Caliva, M. Weber, Arnon Songmoolnak, Juan Manuel Mejia Camacho, Henrique Jose Correia Zanoli, S. P. Sorensen, Nicolas Schmidt, J. Zhu, Rosario Turrisi, David Dobrigkeit Chinellato, Subhadeep Roy, Evgeny Kondratyuk, Jurgen Schukraft, Stefano Boi, Michal Broz, Nikita Vozniuk, Pranjal Sarma, Alex Henri Jean Chauvin, Joyful Elma Mdhluli, Stefano Politano, D. De Gruttola, Victor Trubnikov, Saikat Biswas, Archana Sharma, Rishat Sultanov, Alberto Rotondi, Austin Robert Schmier, James Philip Iddon, Vladimir Ivanov, Evgeny Karpechev, Tomasz Trzcinski, D. L. D. Keijdener, Biao Zhang, Mikhail Sukhanov, Grzegorz Andrzej Wilk, Ranbir Singh, Fabio Catalano, Matthias Richter, Ante Bilandzic, Andre Augustinus, G. Aglieri Rinella, Haavard Helstrup, Vytautas Vislavicius, Petr Nomokonov, Luca Micheletti, Dmitry Aleksandrov, Franck Manso, Alexandra Neagu, Chinorat Kobdaj, V. Chibante Barroso, Raghunath Sahoo, David Horak, Rashmi Raniwala, Anantachai Lakrathok, Luca Quaglia, Igor Pshenichnov, Valerie Ramillien Barret, Sebastian Hornung, Claude Andre Pruneau, Roberto Barbera, Simon Voigt Nesbø, Julien Faivre, Hermann Franz Degenhardt, S. K. Ghosh, Jørgen André Lien, A. M. Gago, Mihai Petrovici, Boris Rumyantsev, S. N. Alam, David Olle Rickard Silvermyr, Pooja Pareek, G. Herrera Corral, Martin Schmidt, William Edward Witt, Adam Tadeusz Wegrzynek, I. Das, L. Cunqueiro, Bruno Espagnon, A. A. Vinogradov, Andrea Alici, Hiroshi Murakami, Arianna Grisel Torres Ramos, Dai-Mei Zhou, G. L. Usai, Teodor Siemiarczuk, Z. Conesa del Valle, D. Elia, Bernd Stefan Windelband, Viljar Nilsen Eikeland, Patrick Huhn, Slavka Jadlovska, Tariq Mahmoud, Sylvain Chapeland, Anders Garritt Knospe, L. V. Malinina, Malgorzata Anna Janik, Iouri Belikov, Thomas Dietel, Ahsan Mehmood Khan, Roman Lietava, Raul Arteche Diaz, Klaus Johannes Reygers, Chiara Zampolli, Sara Vallero, Elena Botta, L. Šerkšnytė, Dong Jo Kim, Dominik Voscek, Roelof Jan Gijs van Weelden, Michael Lettrich, David Karatovic, Varlen Grabski, Jerome Jung, Michal Sumbera, A. A. P. Suaide, Øystein Djuvsland, Philip Hauer, Rutuparna Rath, J. de Cuveland, Deepa Thomas, Y. J. Kwon, A. Grigoryan, Saul Anibal Rodriguez Ramirez, Igor Morozov, Bong-Hwi Lim, Peter Christiansen, Sourav Kundu, Ola Slettevoll Groettvik, Nataliya Topilskaya, Ingrid Mckibben Lofnes, Laszlo Gyulai, Jan Figiel, T. Peitzmann, J. Schambach, Alperen Yuncu, Andreas Morsch, M. R. Haque, Cristian Andrei, Rinaldo Rui, Venelin Anguelov, D. Varga, Adrian Horzyk, You Zhou, Elisa Laudi, Shingo Sakai, Jungeol Kim, Marko Jercic, Sukalyan Chattopadhyay, Marcello Lunardon, Rabi Soto Camacho, Michal Meres, Tiziano Virgili, Markus Fasel, S. R. Klein, Silvia Pisano, Ran Xu, Ana Maria Marin, Zuzana Moravcova, J. Saini, Johanna Stachel, Evgeny Kryshen, G. Boca, B. von Haller, Mike Henry Petrus Sas, Josephina Rae Wright, Dongfang Wang, Jacek Bogumil Biernat, Norbert Novitzky, Ramona Lea, Jonathan Samuel Colburn, Feng Fan, Sergey Evdokimov, Marten Ole Schmidt, Sergio Paisano Guzman, Sonali Padhan, Maksim Melnik Storetvedt, G. de Cataldo, Raquel Estefania Quishpe Quishpe, Y. Zhang, C. Soncco, Dmitry Serebryakov, Nikola Poljak, Alberto Collu, Siraj Ahmed Khan, Z. Yin, Amalia Pop, Rachid Guernane, Debojit Sarkar, Imrich Szarka, Minjung Kim, Alessandra Fantoni, Angela Badala, Syaefudin Jaelani, Laura Fabbietti, Cvetan Valeriev Cheshkov, Nicole Bastid, Radiy Ilkaev, Jeongsu Bok, Chiara Pinto, Surya Prakash Pathak, Fouad Rami, Shi Qiu, A. Fernández Téllez, Horst Sebastian Scheid, Pietro Cortese, Rita Sadek, Carlos Duarte Galvan, Benjamin Donigus, Alice Mulliri, Biswarup Paul, Jacek Tomasz Otwinowski, Zhanna Khabanova, Hartmut Hillemanns, Buddhadeb Bhattacharjee, Boris Wagner, Anand Kumar Dubey, Haidar Mas'Ud Alfanda, Natalia Kondratyeva, Mateusz Andrzej Ploskon, Roberto Preghenella, Sumit Basu, Matteo Concas, Dibakar Bauri, Ankhi Roy, W. H. Trzaska, Mallick Dukhishyam, J.A. Mares, Bongsoo Kim, Sebastian Adam Bysiak, Latchezar Betev, J. J. Gaardhøje, Neetika Sharma, D. Peresunko, Andrei Riabov, Oliver Thomas Jevons, Sanchari Thakur, L. V. R. van Doremalen, Bedangadas Mohanty, Shinichi Hayashi, Sizar Aziz, Laura Brittany Havener, Michael Karim Habib, Filippo Costa, J. R. A. Garcia, Grazia Luparello, Caitlin Beattie, Natalia Dzalaiova, Paraskevi Ganoti, Mohammed Al-Turany, Georgui Kornakov, Bharati Naik, Fabrizio Grosa, M. van Leeuwen, V. Petráček, Ruben Shahoyan, D. A. Moreira De Godoy, Janka Vrlakova, Kirill Lapidus, Suharyo Sumowidagdo, Marta Urioni, Zoltán Varga, Claudiu Cornel Schiaua, Ishaan Ahuja, Gualtiero Volpe, Victor Gonzalez, Lucia Anna Tarasovicova, Andrea Danu, Guillaume Batigne, Ganesh Jagannath Tambave, Adrian Sevcenco, Massimo Angeletti, Jin-Hong Park, Henner Buesching, Stefano Panebianco, Gabor Biro, Vladimir Nikulin, Pawel Grzegorz Russek, Boris Hippolyte, S. L. La Pointe, Monika Varga-Kofarago, Renu Bala, Arun Kumar Yadav, Diego Stocco, Mikael Andreas Molander, Christoph Blume, Andrzej Rybicki, Kosei Yamakawa, Laure Marie Massacrier, E. Calvo Villar, Esther Bartsch, Stefan Kirsch, Sergey Nikulin, Fabio de Moraes Canedo, Piotr Jan Gasik, Vikas Singhal, Antonino Zichichi, Jorge Andres Lopez Lopez, Guillaume Taillepied, Nima Zardoshti, Marcelo Gameiro Munhoz, Valeria Muccifora, A. G. Bogdanov, Vladimir Kaplin, Marek Kowalski, L. H. González-Trueba, K. Barth, Luuk Vermunt, Mikhail Ippolitov, Livia Terlizzi, Natalia Zhigareva, Chunzheng Wang, N. Zaviyalov, J. Wiechula, Mohamad Tarhini, Cristiane Jahnke, C. Oppedisano, Yongzhen Hou, Catalin-Lucian Ristea, Vitaly Loginov, A. C. Oliveira Da Silva, Vikash Sumberia, Y. Wu, Yongwook Baek, Lidia Maria Gorlich, Kenneth Francis Read, Stefania Bufalino, Podist Kurashvili, A. V. Kazantsev, L. Nellen, Gian Michele Innocenti, Christos Pliatskas Stylianidis, Sanghoon Lim, Antonio Uras, Elisa Meninno, H. Pereira Da Costa, Theraa Tork, Y. Sekiguchi, Inayat Rasool Bhat, G. Tejeda Muñoz, Maciej Slupecki, Piotr Jan Konopka, T. J. Humanic, Robin Albert Andre Caron, James Declan Mulligan, Barbara Ewa Erazmus, Andrea Dubla, Y. Schutz, Giuseppe Simonetti, Ivan Ravasenga, Ralf Peter Averbeck, S. Beole, Maya Hachiya Shimomura, A. Maire, Anton Jusko, Ivan Kralik, Miroslav Pikna, Mario Sitta, Giacomo Contin, Michelangelo Agnello, Z. Rescakova, Satoshi Yano, Vivek Singh, Martin Kroesen, Paolo Martinengo, Artem Isakov, Mihaela Gabriela Besoiu, O. Vazquez Doce, Anthony Robert Timmins, Haakon Andre Reme-Ness, Adam Ryszard Kisiel, M. Guilbaud, Miroslaw Jablonski, Alberica Toia, Magnus Mager, Ashish Jalotra, Nasir Mehdi Malik, Costin Grigoras, Ida Storehaug, Daniel Michael Muhlheim, Pietro Antonioli, Luisa Cifarelli, Rajendra Nath Patra, Serpil Yalcin, Hushnud Hushnud, Ali Zaman, Z. Buthelezi, Giulia Clai, Sebastian Dominik Koryciak, Marco Marquard, Sabyasachi Siddhanta, Takuya Kumaoka, Serhiy Senyukov, Susanna Costanza, Magnus Rentsch Ersdal, Edmundo Javier Garcia-Solis, C. Garabatos, Alberto Masoni, Anjaly Sasikumar Menon, Jan Fiete Grosse-Oetringhaus, Lee Stuart Barnby, Igor Altsybeev, Davide Pagano, Y. Mao, Mohammad Asif Bhat, J. S. Kim, Gennady Zinovjev, Adrian Florin Mechler, Sadhana Dash, Dieter Røhrich, Seyong Kim, Y. Melikyan, Pengyao Cui, Nicole Alice Martin, Martin Vala, Nicole Apadula, Sibaliso Mhlanga, Udo Wolfgang Kebschull, Qasim Waheed Malik, A. N. Mishra, Gabriele Fiorenza, Alexandru Bercuci, Pascal Dupieux, Andrea Dainese, Sergey Fokin, Torsten Alt, Matthew Daniel Buckland, Thomas Michael Cormier, Lokesh Kumar, Hua Pei, Y. Yamaguchi, Navneet Kumar, K. Krizkova Gajdosova, Matthias Kleiner, Uzma Tabassam, Jasper Elias Parkkila, Guillermo Mesa Perez, Georgijs Skorodumovs, Simone Ragoni, Oleksandr Kovalenko, Wadut Shaikh, Giuseppe Trombetta, G. Conesa Balbastre, Peter Martin Jacobs, Bartosz Balis, Sven Gotovac, Zabulon Vilakazi, Roman Lavicka, Arturo Alejandro Menchaca-Rocha, Jon Christopher Wikne, Gioacchino Vino, Giacomo Bruno, Charles E. Hughes, L. Aphecetche, Ernst Hellbar, D. Hatzifotiadou, Dmitry Blau, Dong Hai Liu, M. Keil, Laszlo Boldizsar, J. Takahashi, Andreas Michael Mathis, Luciana Bianchi, Sergey Gorbunov, A. R. Redelbach, Oveis Sheibani, Wioleta Rzesa, Rune Langøy, Roberta Arnaldi, Nilmoni Sarkar, Vladimir Vechernin, Yasir Ali, Jon-Are Saetre, Vito Manzari, Arvind Khuntia, Viktor Riabov, Kristjan Herlache Gulbrandsen, Teo Mrnjavac, Tulika Tripathy, Johannes Peter Wessels, C. Anuj, Gilda Scioli, Z. Akbar, Richa Gupta, Sudipan De, Guy Paic, Seoyoung Noh, Alexandru Florin Dobrin, Roberto Divia, S. Porteboeuf-Houssais, Yvonne Chiara Pachmayer, Purba Bhattacharya, Mohd Danish Azmi, Peter Malzacher, Markus Konrad Kohler, Jetnipit Kaewjai, Mesut Arslandok, Alexei Khanzadeev, Lukasz Kamil Graczykowski, Valentina Mantovani Sarti, Basanta Kumar Nandi, Kristin Fanebust Hetland, Svetlana Kushpil, Antonina Rosano, I. León Monzón, C. Cicalo, Sergey Kiselev, A. De Falco, Adrian Fereydon Nassirpour, Alom Antonio Paz Jimenez, P. Gianotti, Georgy Tersimonov, P. Vande Vyvre, Bas Hofman, Taku Gunji, Alexander Schmah, Paul Alois Buhler, Aydan Garibli, Maria Vasileiou, A. M. Rossi, A. Baldisseri, Nicola Zurlo, Vladimir Kovalenko, Shiming Yang, Hira Ilyas, Jakub Kvapil, Auro Prasad Mohanty, A. Di Mauro, Tim Sebastian Rogoschinski, Peter Braun-Munzinger, Sanjeev Singh Sambyal, A. Nath, Valeriy Pozdniakov, Jacek Kitowski, Lukas Kreis, A. Kondratyev, E. A. R. Casula, Ralf Keidel, Sergey Shirinkin, P. Larionov, S. Vergara Limón, Peter Levai, Gergely Gabor Barnafoldi, Sarita Sahoo, Giuseppe Mandaglio, Joshua Leon Konig, L. A. P. Moreno, Christoph Mayer, Jens Robert Luhder, Filippo Baruffaldi, Sergey Filchagin, Marco Bregant, Oskari Antti Matti Saarimaki, A. D. C. Bell Hechavarria, F. Prino, B. Polichtchouk, Luisa Bergmann, Thomas Janson, Laboratoire de physique subatomique et des technologies associées (SUBATECH), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), ALICE, Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)
Subjects: Particle physics, p p: scattering, Physics and Astronomy (miscellaneous), Meson, Hadron, Nuclear Theory, strange meson, Strangeness, transverse momentum, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], hyperon, 01 natural sciences, High Energy Physics - Experiment, Pion, ALICE, jet: fragmentation, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], multiplicity, Nuclear Physics - Experiment, 010306 general physics, Nuclear Experiment, Engineering (miscellaneous), Monte Carlo, Physics, angular correlation: two-particle, 010308 nuclear & particles physics, Hyperon, Multiplicity (mathematics), trigger, Baryon, CERN LHC Coll, correlation, 13000 GeV-cms/nucleon, PYTHIA, Production (computer science), High Energy Physics::Experiment, hadron, Particle Physics - Experiment, experimental results
Abstract: Two-particle azimuthal correlations are measured with the ALICE apparatus in pp collisions at $\sqrt{s} = 13$ TeV to explore strangeness- and multiplicity-related effects in the fragmentation of jets and the transition regime between bulk and hard production, probed with the condition that a strange meson (K$^{0}_{\rm S}$) or baryon ($\Lambda$) with transverse momentum $p_{\rm T} > 3$ GeV/c is produced. Azimuthal correlations between kaons or $\Lambda$ hyperons with other hadrons are presented at midrapidity for a broad range of the trigger ($3 < p_{\rm T}^{\rm trigg} < 20$ GeV/$c$) and associated particle $p_{\rm T}$ (1 GeV/$c$ $< p_{\rm T}^{\rm assoc} < p_{\rm T}^{\rm trigg}$), for minimum-bias events and as a function of the event multiplicity. The near- and away-side peak yields are compared for the case of either K$^{0}_{\rm S}$ or $\Lambda$($\overline{\Lambda}$) being the trigger particle with that of inclusive hadrons (a sample dominated by pions). In addition, the measurements are compared with predictions from PYTHIA 8 and EPOS LHC event generators., Comment: 25 pages, 10 captioned figures, 2 tables, authors from page 20, published version, figures at http://alice-publications.web.cern.ch/node/7263
Published: 2021

49. Charged-particle multiplicity fluctuations in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 2.76 TeV

Author: Anik Gupta, Alexander Adler, Alessandro Balbino, Maya Hachiya Shimomura, A. Maire, Anton Jusko, Ivan Kralik, Miroslav Pikna, Mario Sitta, Florian Herrmann, Massimo Lamanna, Giacomo Contin, Mesut Arslandok, Alexei Khanzadeev, Sanjib Muhuri, P. Roy, Marco Toppi, V. Samsonov, Michelangelo Agnello, K. Šafařík, Z. Rescakova, Lukasz Kamil Graczykowski, Satoshi Yano, Valentina Mantovani Sarti, P. F. T. Matuoka, Ulrich Fuchs, Jihye Song, Corrado Gargiulo, Paolo Martinengo, Basanta Kumar Nandi, Roman Rogalev, Prottoy Das, Tariq Mahmoud, Sylvain Chapeland, O. Vazquez Doce, Omar Vazquez Rueda, Anthony Robert Timmins, Haakon Andre Reme-Ness, Adam Ryszard Kisiel, Kristin Fanebust Hetland, Svetlana Kushpil, Yue Shi Lai, Antonina Rosano, Erin Frances Gauger, Vit Kucera, Costin Grigoras, Rinaldo Rui, Premomoy Ghosh, Maurice Louis Coquet, Konstantin Mikhaylov, R. J. Ehlers, Anisa Khatun, Iwona Anna Sputowska, Ida Storehaug, I. León Monzón, C. Cicalo, Sergey Evdokimov, Emma Gonzalez Hernandez, Alessandro Ferretti, Silvia Pisano, Dmitry Blau, Johannes Lehrbach, Daniel Michael Muhlheim, Sebastian Dominik Koryciak, M. Keil, Zuzana Moravcova, Y. Zhi, R. Cruz-Torres, Haidar Mas'Ud Alfanda, Z. Yin, Syaefudin Jaelani, Alberto Collu, Jhuma Ghosh, Sabyasachi Siddhanta, Sergey Gorbunov, Attiq Ur Rehman, A. R. Redelbach, G. de Cataldo, Jasper Elias Parkkila, Motoi Inaba, Jin Hee Yoon, Raquel Estefania Quishpe Quishpe, C. Garabatos, Oveis Sheibani, Wioleta Rzesa, Rafael Peretti Pezzi, Alberto Masoni, Mauro Rogerio Cosentino, M. O. Schmidt, Rune Langøy, Roberta Arnaldi, Laura Fabbietti, Carlos Duarte Galvan, H. Borel, Buddhadeb Bhattacharjee, Boris Wagner, K. Schweda, Rosario Nania, Guillermo Mesa Perez, Georgijs Skorodumovs, J. de Cuveland, Deepa Thomas, Teo Mrnjavac, Alessandra Fantoni, Aleksey M. Tikhonov, Oleksandr Kovalenko, Wadut Shaikh, Giuseppe Trombetta, Chiara Zampolli, Y. Mao, Sukalyan Chattopadhyay, Marcello Lunardon, Sara Vallero, Tulika Tripathy, Fabio Filippo Colamaria, Angela Badala, Sumit Basu, Michael Jung, J. Saini, Dibakar Bauri, Ali Zaman, Z. Buthelezi, Giulia Clai, C. Anuj, Amalia Pop, G. Conesa Balbastre, Rachid Guernane, Gilda Scioli, Jeremy John Wilkinson, Agneta Oskarsson, J. S. Kim, Imrich Szarka, Minjung Kim, Adrian Florin Mechler, Nicole Bastid, A. Matyja, Xiaozhi Bai, Janusz Oleniacz, Y. Berdnikov, Ana Vargas, Zebo Tang, Vytautas Vislavicius, Jeongsu Bok, Peter Martin Jacobs, Jon Christopher Wikne, Shinichi Hayashi, Gioacchino Vino, Mallick Dukhishyam, Giacomo Bruno, Charles E. Hughes, Klaus Johannes Reygers, Dominik Voscek, Hartmut Hillemanns, Roelof Jan Gijs van Weelden, Ankhi Roy, Z. Akbar, Richa Gupta, Marco Marquard, D. Hatzifotiadou, Bedangadas Mohanty, Laszlo Boldizsar, J. Takahashi, Sebastian Adam Bysiak, Paolo Giubellino, Latchezar Betev, Haavard Helstrup, J. J. Gaardhøje, Sudipan De, Anders Garritt Knospe, L. V. Malinina, J. R. A. Garcia, D. Berenyi, Linda Vickovic, Georgui Kornakov, Philippe Crochet, Nicolo Jacazio, Matthew Daniel Buckland, M. Weber, Arnon Songmoolnak, Leo Clifford Greiner, Guy Paic, Anand Kumar Dubey, M. Bombara, Iouri Belikov, Thomas Dietel, David Dobrigkeit Chinellato, J.A. Mares, Luca Micheletti, Vladimir Zherebchevskii, Neelkamal Mallick, Vito Manzari, Arvind Khuntia, Viktor Riabov, Yunlong Zhang, Seoyoung Noh, Thomas Michael Cormier, Lokesh Kumar, Hua Pei, Bharati Naik, Kirill Lapidus, Taku Gunji, Michael Karim Habib, Grazia Luparello, Caitlin Beattie, Natalia Dzalaiova, Saikat Biswas, S. Sadovsky, Christopher Hills, Dushmanta Sahu, Domenico Colella, Martin Andreas Volkl, Alexandru Florin Dobrin, Manuel Colocci, Marko Jercic, Roman Lietava, Tatiana Lazareva, Christian Holm Christensen, Ganesh Jagannath Tambave, E. López Torres, Roberto Divia, S. Porteboeuf-Houssais, Jin-Hong Park, Henner Buesching, Takuya Kumaoka, You Zhou, Maciej Slupecki, Piotr Jan Konopka, Paraskevi Ganoti, Mohammed Al-Turany, David Olle Rickard Silvermyr, Christine Nattrass, Yvonne Chiara Pachmayer, S. L. La Pointe, Martin Schmidt, David H. Evans, Peter Christiansen, Peter Kalinak, Marianna Mazzilli, Adriana Telesca, Monika Varga-Kofarago, Franco Meddi, Dmitry Aleksandrov, Pavel Larionov, Franck Manso, Alexandra Neagu, Purba Bhattacharya, Sanchari Thakur, Mohd Danish Azmi, Peter Malzacher, Patrick John Steffanic, Y. Yamaguchi, Dimitra Andreou, Andrey Zarochentsev, Austin Vincent Harton, Chun-Lu Huang, Fabrizio Grosa, Archana Sharma, Chinorat Kobdaj, C. J. Schmidt, Rajendra Nath Patra, Serpil Yalcin, Hushnud Hushnud, J. L. Bazo Alba, Rishat Sultanov, Petr Zavada, Diego Stocco, Germano Bonomi, Sonali Padhan, Serhiy Senyukov, Susanna Costanza, Maksim Melnik Storetvedt, C. Hadjidakis, Magnus Rentsch Ersdal, T. J. Humanic, Robin Albert Andre Caron, Hadi Hassan, Jan Jadlovsky, James Declan Mulligan, M. van Leeuwen, Andrea Alici, Laszlo Gyulai, T. Peitzmann, G. Boca, Edmundo Javier Garcia-Solis, Markus Konrad Kohler, Christina Markert, Przemyslaw Stefan Rokita, Zoltán Varga, Alexander Schmah, Laura Brittany Havener, Dhruv Utpalkumar Dixit, Arianna Grisel Torres Ramos, M. Masera, Victor Gonzalez, Sarita Sahoo, Giuseppe Mandaglio, Anjaly Sasikumar Menon, Dai-Mei Zhou, A. Rakotozafindrabe, Jan Fiete Grosse-Oetringhaus, Gabriel Garcia Guardiano, Jetnipit Kaewjai, Z. Conesa del Valle, Silvia Arcelli, Igor Altsybeev, Joshua Leon Konig, L. A. P. Moreno, Christoph Mayer, Lucia Anna Husova, Sang Un Ahn, Valentina Zaccolo, Hans Rudolf Schmidt, Marco Giacalone, Davide Pagano, Barbara Ewa Erazmus, J. W. Harris, Seyed Farid Taghavi, Adrian Sevcenco, Alice Mulliri, Peter Matthew Bond, G. Hamar, Dong Jo Kim, Biswarup Paul, Ionut Cristian Arsene, Seyong Kim, Bhawani Singh, Mihail Bogdan Blidaru, Stefano Panebianco, Y. Melikyan, J. Zhu, Antoine Jean-Simon Junique, Shi Qiu, Paul Alois Buhler, Aydan Garibli, Jacek Tomasz Otwinowski, Zhanna Khabanova, Andrea Dubla, Arturo Tauro, E. Nappi, Susan L. Swain, Lucas Altenkamper, Anna Onnerstad, Pranjal Sarma, Y. F. Ryabov, Thomas Klemenz, Nicole Apadula, Udo Wolfgang Kebschull, Gabriele Fiorenza, Pascal Dupieux, Andrea Dainese, Y. Pestov, Boris Rumyantsev, Yasuo Miake, Sinjini Chandra, Sergey Fokin, Bongsoo Kim, Mohammad Asif Bhat, Gennady Zinovjev, Soyeon Cho, A. Alkin, Xinye Peng, Florian Eisenhut, Cristian Andrei, Pietro Cortese, Torsten Alt, Venelin Anguelov, Rita Sadek, Debjani Banerjee, Ahsan Mehmood Khan, A. Harlenderova, Jens Robert Luhder, Navneet Kumar, K. Krizkova Gajdosova, Matthias Kleiner, Fernando Antonio Flor, Michal Meres, Tiziano Virgili, Markus Fasel, S. N. Alam, Davide Caffarri, A. Ortiz Velasquez, X. L. Li, Nicolo' Valle, Silvia Masciocchi, Abhi Modak, Marek Gorgon, Lee Stuart Barnby, Wenya Wu, Pradip Kumar Sahu, Antonio Trifiro, D. A. Moreira De Godoy, Piero Giubilato, Sadhana Dash, Dieter Røhrich, Filippo Baruffaldi, Michal Sumbera, L. V. R. van Doremalen, Sergey Filchagin, Marco Bregant, A. A. P. Suaide, Y. Schutz, Giuseppe Simonetti, Vivek Singh, Ivan Ravasenga, Romain Schotter, Claudiu Cornel Schiaua, Ishaan Ahuja, V. Petráček, Ruben Shahoyan, A. Baldisseri, Przemyslaw Karczmarczyk, Oskari Antti Matti Saarimaki, Pengyao Cui, Nicole Alice Martin, Mengke Cai, O. Villalobos Baillie, Christian Lippmann, Luis Gustavo Pereira, E. Fragiacomo, Shengkun Zhang, Janka Vrlakova, Andrei Riabov, Austin Robert Schmier, Jakub Kvapil, Suman Deb, Federico Antinori, M. V. Ivanov, D. L. D. Keijdener, Jan Musinsky, J. G. Contreras, Ralf Peter Averbeck, S. Beole, Andrey Erokhin, Thibaut Albert Rancien, Ian Gardner Bearden, Eszter Frajna, Daiki Sekihata, Yingchun Zhu, Alexey Kuryakin, N. Zaviyalov, Ombretta Pinazza, Piotr Nowakowski, Andrea Danu, Guillaume Batigne, Oliver Thomas Jevons, Massimo Angeletti, Pawel Grzegorz Russek, Martin Kroesen, Artem Isakov, Paolo Camerini, Sergey Voloshin, Ophelie Bugnon, Kenta Shigaki, Takumi Osako, Felix Reidt, V. Chibante Barroso, Raghunath Sahoo, Valerie Ramillien Barret, Martin Vala, Pietro Fecchio, Sizar Aziz, Jungeol Kim, Alla Maevskaya, A. D. C. Bell Hechavarria, Sean Murray, Alexander Akindinov, D. Miśkowiec, M. I. Martínez, Svetlana Belokurova, Panagiotis Christakoglou, Ranbir Singh, A. B. Kurepin, Julian Wojciech Myrcha, Sibaliso Mhlanga, Hannah Bossi, Rahul Ramachandran Nair, Mirko Planinic, F. Prino, B. Polichtchouk, Simon Voigt Nesbø, Tuva Ora Herenui Richert, Siyu Tang, Andrey Vasiliev, C. Soncco, Luisa Bergmann, Viljar Nilsen Eikeland, C. Klein-Bösing, Sumit Kumar Saha, Xuan Zhang, Antonio Palasciano, Mihaela Gabriela Besoiu, M. Guilbaud, Federico Cindolo, Miroslaw Jablonski, Alberica Toia, Magnus Mager, Renu Bala, Christoph Blume, Pietro Antonioli, Andrzej Rybicki, Jacopo Pazzini, Gokhan Halimoglu, Kosei Yamakawa, Yu. V. Kharlov, Enrico Scomparin, Ionel Stan, Mohammed Hamid, Qasim Waheed Malik, A. N. Mishra, Alexandru Bercuci, Ritsuya Hosokawa, Katharina Garner, Jinjin Pan, Michael Lettrich, Olja Dordic, Stephan Friedrich Stiefelmaier, J. Wiechula, Mohamad Tarhini, Cristiane Jahnke, Dmitry Serebryakov, Nikola Poljak, Corey James Myers, Benedikt Volkel, C. Oppedisano, Mikhail Malaev, Kirill Voloshin, Debojit Sarkar, A. S. Nyanin, Luisa Cifarelli, Laure Marie Massacrier, Esther Bartsch, T. P. Sinha, Malgorzata Anna Janik, F. Bock, Deekshit Kumar, Peter Zahariev Hristov, Ken Oyama, Himanshu Sharma, Arthur Willem Jean Gal, Rainer Arno Ernst Renfordt, Nima Zardoshti, Fiorella Maria Celeste Fionda, Meike Charlotte Danisch, Thomas Janson, A. Karasu Uysal, Jaehyeon Do, Solangel Rojas Torres, Auro Prasad Mohanty, Nikolai Smirnov, Rutuparna Rath, Joonil Lee, Gabor Biro, Hanna Paulina Zbroszczyk, Raphael Noel Tieulent, Antonio Lafuente Mazuecos, Markus Ball, Giulio Eulisse, Francesca Bellini, Kilian Eberhard Schwarz, Øystein Djuvsland, Adrian Horzyk, Uzma Tabassam, Eunja Kim, James Philip Iddon, Toru Sugitate, Vladimir Ivanov, A. Di Mauro, Catalin-Lucian Ristea, Vitaly Loginov, A. C. Oliveira Da Silva, Janet Elizabeth Seger, Petr Nomokonov, David Horak, Rashmi Raniwala, Anantachai Lakrathok, Tim Sebastian Rogoschinski, Vikash Sumberia, Adela Kravcakova, D. Mal'Kevich, S. T. Heckel, M. Mohisin Khan, Borge Svane Nielsen, Preeti Dhankher, Robert Helmut Munzer, Yudi Ma, L. H. González-Trueba, Sudhir Pandurang Rode, K. Barth, Luuk Vermunt, Y. Wu, Jan Anton Hasenbichler, Yongwook Baek, Lidia Maria Gorlich, Kenneth Francis Read, Xavier Bernard Lopez, Jaroslav Bielcik, Mario Kruger, Federico Ronchetti, Peter Braun-Munzinger, Sanjeev Singh Sambyal, W. Deng, Guido Alexander Willems, G. L. Usai, D. Budnikov, P. G. Kuijer, Artem Kotliarov, Peter Chochula, Partha Pratim Bhaduri, Christophe Pierre Suire, Mukesh Sharma, Bernhard Hohlweger, Sandeep Dudi, G. Bencedi, Simone Ragoni, Alexander Szabo, Filip Krizek, Krzysztof Redlich, Yanchun Ding, Wladyslaw Henryk Trzaska, Sami Sakari Rasanen, Juan Manuel Mejia Camacho, Kunal Garg, David Michael Rohr, Mikhail Ippolitov, Livia Terlizzi, Madalina-Gabriela Tarzila, Martin Poghosyan, Maximiliano Puccio, F. Soramel, J. L. Klay, A. Rustamov, Barbara Jacak, Artem Shangaraev, Alexander Philipp Kalweit, Uliana Dmitrieva, A. Nath, Chunzheng Wang, Valeriy Pozdniakov, Jacek Kitowski, Lukas Kreis, Luca Quaglia, Anju Bhasin, Branislav Sitar, Elisa Laudi, Sebastian Hornung, Claude Andre Pruneau, Sidharth Kumar Prasad, G. A. Feofilov, Stefania Bufalino, Annalisa Mastroserio, Somnath Kar, Raimond Snellings, Kjetil Ullaland, N. De Marco, Ryan Patrick Hannigan, Elena Rogochaya, Lukas Lautner, Raphaelle Marie Bailhache, B. Ketzer, Bartosz Balis, Supriya Das, Artur Furs, Adrian Liu, Podist Kurashvili, Sven Gotovac, Vladislav Manko, Nicola Rubini, A. Kondratyev, Zabulon Vilakazi, C. De Martin, A. V. Kazantsev, E. A. R. Casula, Filip Erhardt, Lars Bratrud, L. Nellen, Francesco Riggi, Panagiota Foka, Evgeny Karpechev, Tomasz Trzcinski, Roberto Barbera, Elena Botta, G. Aglieri Rinella, Purushottam Chakraborty, J. Porter, L. Šerkšnytė, Roman Lavicka, Jerome Jung, Jochen Klein, Eugen Mudnic, Ralf Keidel, Rosario Turrisi, Nicola Funicello, M. Zhalov, Evgeny Kondratyuk, S. K. Ghosh, Masanori Ogino, Dmitrii Nesterov, Francesca Carnesecchi, Teodor Siemiarczuk, Tabea Maria Eder, Arseniy Shabanov, Werner Riegler, T.H. Kim, Sergey Shirinkin, Andrea Ferrero, E. Calvo Villar, Ermanno Vercellin, Trine Spedstad Tveter, Vladimir Belyaev, J. T. Blair, Stefan Kirsch, Petra Loncar, Marian Krivda, Subhadeep Roy, I. K. Yoo, Stephan Alexander Konigstorfer, Jørgen André Lien, Lukas Koska, William Edward Witt, Daniel Jia Qin Goh, Ivan Kisel, Sergey Nikulin, Arturo Alejandro Menchaca-Rocha, S. Vergara Limón, Peter Levai, Tonatiuh Garcia Chavez, J. Castillo Castellanos, Fabio de Moraes Canedo, Piotr Jan Gasik, Jonatan Adolfsson, Ernst Hellbar, Andreas Michael Mathis, A. M. Gago, Adam Tadeusz Wegrzynek, Josephina Rae Wright, Luciana Bianchi, Gian Michele Innocenti, Christos Pliatskas Stylianidis, Fabian Pliquett, Mikolaj Krzewicki, Bruno Espagnon, Peter Glassel, Francesca Ercolessi, A. A. Vinogradov, Philippe Pillot, Silvia Delsanto, Alexandre Shabetai, Jiyeon Kwon, Baidyanath Sahoo, Vikas Singhal, Raffaele Grosso, Feng Fan, Jamila Bashir Butt, Y. Sibiriak, Antonino Zichichi, Jorge Andres Lopez Lopez, Guillaume Taillepied, Jurgen Schukraft, Ilya Selyuzhenkov, Sourav Kundu, Ola Slettevoll Groettvik, Marcelo Gameiro Munhoz, Miljenko Suljic, Grzegorz Andrzej Wilk, Y. J. Kwon, Pablo Fierro Rojas, Igor Morozov, Philip Hauer, Matthias Richter, Rabi Soto Camacho, Gergely Gabor Barnafoldi, Valeria Muccifora, A. G. Bogdanov, Victor Trubnikov, Nilmoni Sarkar, Benjamin Donigus, Irais Bautista Guzman, Vladimir Kaplin, Vladimir Vechernin, Yasir Ali, Jon-Are Saetre, Joakim Nystrand, Jacobb Lee Martinez, Edgar Dominguez Rosas, M. A. Mazzoni, Fabio Catalano, Oleg Karavichev, Christian Claude Kuhn, Julien Faivre, Ante Bilandzic, Nataliya Topilskaya, Norbert Novitzky, Sergey Kiselev, Ramona Lea, Jonathan Samuel Colburn, Lucrezia Camilla Migliorin, Marek Kowalski, Anastasia Berdnikova, Hiroshi Murakami, Stefano Trogolo, Sergio Paisano Guzman, Chiara Pinto, S. De Pasquale, A. Grigoryan, Shafiq Ahmad, Sanghoon Lim, G. Herrera Corral, Francesco Noferini, L. Dello Stritto, Shreyasi Acharya, H. Appelshäuser, Ketil Røed, Sergey Nikolaev, Kristjan Herlache Gulbrandsen, Johannes Peter Wessels, Tebogo Joyce Shaba, Lawrence Pinsky, L. Cunqueiro, A. De Falco, Ana Maria Marin, T. Kollegger, Adrian Fereydon Nassirpour, A. Feliciello, Patrick Simon Reichelt, Ran Xu, Eleazar Cuautle, P. Gianotti, Johanna Stachel, Constantinos Loizides, Hiroki Yokoyama, Alexander Borissov, Hideki Hamagaki, Georgy Tersimonov, P. Vande Vyvre, Bas Hofman, Alexander Bolozdynya, Stefano Boi, Antonio Uras, Tatsuya Chujo, Elisa Meninno, Michal Broz, Alberto Rotondi, H. Pereira Da Costa, Mattia Faggin, Luciano Musa, Theraa Tork, Patrick Huhn, Maria Vasileiou, A. M. Rossi, Slavka Jadlovska, Anton Andronic, J. Schambach, Milan Tkacik, Amanda Nicole Flores, Nicola Zurlo, Vladimir Kovalenko, Andreas Morsch, M. R. Haque, Shingo Sakai, Luca Barioglio, Brigitte Cheynis, L. De Cilladi, Shiming Yang, Hira Ilyas, Igor Pshenichnov, I. Das, V. Grigoriev, Ingrid Mckibben Lofnes, Marta Verweij, Jan Figiel, Alperen Yuncu, Y. Sekiguchi, Inayat Rasool Bhat, Dongfang Wang, Jacek Bogumil Biernat, Vladimir Izucheev, G. Tejeda Muñoz, Tomas Herman, Toralf Bernhard Skaali, Amrit Gautam, Michael Henry Oliver, Laurent Bernard Aphecetche, Stefano Piano, F. Torales-Acosta, D. J. Kim, G. Martínez García, Bruno Alessandro, Michael Rudolf Ciupek, Anselmo Margotti, Victor Jose Gaston Feuillard, Cvetan Valeriev Cheshkov, Radiy Ilkaev, Alek Hutson, H. Caines, Sudhir Raniwala, Tatiana Karavicheva, S. Sharma, Heidi Maria Rytkonen, C. Ceballos Sanchez, Surya Prakash Pathak, Fouad Rami, Boris Batyunya, Sandro Christian Wenzel, Shiming Yuan, Aude Marie Camille Glaenzer, A. De Caro, R. Alfaro Molina, Marielle Chartier, Evgeny Ryabinkin, Dagmar Adamová, Florian Paul Andre Damas, Amelia Lindner, Dmitry Finogeev, Rene Bellwied, Florian Jonas, Pragati Sahoo, Hermann Franz Degenhardt, Monika Joanna Jakubowska, Raul Arteche Diaz, Dirk Hutter, David Karatovic, Saul Anibal Rodriguez Ramirez, Neelima Agrawal, S. R. Klein, M. Rodríguez Cahuantzi, M. J. Kweon, Evgeny Kryshen, Siraj Ahmed Khan, M. S. Islam, John Jowett, D. L. Mihaylov, Martino Gagliardi, Roberto Preghenella, Clara Bartels, D. Di Bari, Matteo Concas, Roy Crawford Lemmon, Tapan K. Nayak, Vitaly Okorokov, Jana Bielcikova, Ivan Vorobyev, Jin Joo Seo, Alessandro Grelli, Siegfried Valentin Foertsch, Robert Vertesi, Muhammad Umair Naru, Bjarte Kileng, M. Winn, Xing Long Li, Jaime Norman, N. van der Kolk, Nicola Bianchi, Mustafa Anaam, Kamil Rafal Deja, Peter Graham Jones, Smbat Grigoryan, Gvozden Neskovic, Rainer Martin Schicker, Andre Augustinus, Marie Germain, Alice Elisabeth Ohlson, Jan Honermann, Ezra Douglas Lesser, Alexander Vodopyanov, Yoshini Bailung, Alexandr Tumkin, Geun Hee Hong, Tiago Fiorini da Silva, S. Saha, Oliver Matonoha, Sushanta Tripathy, Cristina Terrevoli, Francesco Mazzaschi, A. Fernández Téllez, Horst Sebastian Scheid, Natalia Kondratyeva, Mateusz Andrzej Ploskon, Neetika Sharma, D. Peresunko, Filippo Costa, Suharyo Sumowidagdo, Marta Urioni, Gualtiero Volpe, Vladimir Nikulin, Boris Hippolyte, Alexander Kluge, Jian Liu, G. V. Margagliotti, M. Mukherjee, Sebastien Perrin, Zubayer Ahammed, Johan Alme, Luciano Ramello, Bushra Ali, Q. Y. Shou, Maria Barlou, Negin Alizadehvandchali, Christophe Furget, Jean Willy Andre Cleymans, Volker Lindenstruth, Barbara Antonina Trzeciak, P. La Rocca, Alberto Caliva, Henrique Jose Correia Zanoli, S. P. Sorensen, Nicolas Schmidt, Dezso Varga, Alex Henri Jean Chauvin, Joyful Elma Mdhluli, Stefano Politano, D. De Gruttola, Mihai Petrovici, Pooja Pareek, D. Elia, Bernd Stefan Windelband, Varlen Grabski, Bong-Hwi Lim, B. von Haller, Mike Henry Petrus Sas, Cindy Mordasini, Laboratoire de physique subatomique et des technologies associées (SUBATECH), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), ALICE, Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)
Subjects: heavy ion: scattering, CERN Lab, Physics and Astronomy (miscellaneous), FOS: Physical sciences, Context (language use), QC770-798, transverse momentum, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], Astrophysics, 01 natural sciences, 2760 GeV-cms/nucleon, High Energy Physics - Experiment, Nuclear physics, charged particle: multiplicity, High Energy Physics - Experiment (hep-ex), ALICE, multiplicity [charged particle], scattering [heavy ion], Nuclear and particle physics. Atomic energy. Radioactivity, 0103 physical sciences, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Rapidity, Nuclear Physics - Experiment, ddc:530, Nuclear Experiment (nucl-ex), 010306 general physics, peripheral, impact parameter, Nuclear Experiment, Engineering (miscellaneous), Monte Carlo, Physics, 010308 nuclear & particles physics, multiplicity: fluctuation, Multiplicity (mathematics), Charged particle, QB460-466, Amplitude, CERN LHC Coll, rapidity, Pseudorapidity, fluctuation [multiplicity], Quark–gluon plasma, High Energy Physics::Experiment, Impact parameter, Particle Physics - Experiment, experimental results
Abstract: The European physical journal / C 81(11), 1012 (2021). doi:10.1140/epjc/s10052-021-09784-4, Measurements of event-by-event fluctuations of charged-particle multiplicities in Pb��Pb collisions at $\sqrt{s_{\mathrm {NN}}}$ $=$ 2.76 TeV using the ALICE detector at the CERN Large Hadron Collider (LHC) are presented in the pseudorapidity range $|\eta, Published by Springer, Heidelberg
Published: 2021

50. Repurposing mechanistic insight of PDE-5 inhibitor in cancer chemoprevention through mitochondrial-oxidative stress intervention and blockade of DuCLOX signalling

Author: Abdulaziz S. Saeedan, Gaurav Kaithwas, Subhadeep Roy, Manjari Singh, Mohd Nazam Ansari, Sweta Kasna, and Sara Aldosary
Subjects: 0301 basic medicine, Cancer Research, Carcinogenesis, Lipoxygenase, Mammary gland, Mitochondrial stress, Apoptosis, Pharmacology, medicine.disease_cause, N-methyl-n-nitrosourea, Tadalafil, chemistry.chemical_compound, 0302 clinical medicine, Heart Rate, chemistry.chemical_classification, Caspase 8, PDE-5 inhibitor, ER+ mammary gland cancer, Caspase 3, Methylnitrosourea, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Mitochondria, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Female, Inflammation Mediators, Signal Transduction, Research Article, Mammary Gland Tissue, Haematoxylin, lcsh:RC254-282, 03 medical and health sciences, Genetics, medicine, Animals, Rats, Wistar, Mammary Neoplasms, Experimental, Fatty acid, Phosphodiesterase 5 Inhibitors, Rats, Staining, Oxidative Stress, 030104 developmental biology, chemistry, Prostaglandin-Endoperoxide Synthases, Reactive Oxygen Species, DuCLOX, Oxidative stress
Abstract: Background This study evaluates the anti-cancer effects of Tadalafil (potent PDE-5 inhibitor) in female albino wistar rats against n-methyl n-nitrosourea induced mammary gland carcinogenesis. Methods The animals were selected and randomly divided among four groups and each group contains six animals per group. The animal tissue and serum samples were evaluated for the presence of antioxidant parameters and the cellular morphology was studied using carminic staining, haematoxylin staining and scanning electron microscopy followed by immunoblotting analysis. Results On the grounds of hemodynamic recordings and morphology, n-methyl n-nitrosourea treated group showed distorted changes along with distorted morphological parameters. For morphological analysis, the mammary gland tissues were evaluated using scanning electron microscopy, whole mount carmine staining, haematoxylin and eosin staining. The serum samples were evaluated for the evaluation of oxidative stress markers and inflammatory markers. The level of caspase 3 and 8 were also evaluated for the estimation of apoptosis. The fatty acid profiling of mammary gland tissue was evaluated using fatty acid methyl esters formation. The mitochondrial mediated apoptosis and inflammatory markers were evaluated using immunoblotting assay. Conclusion The results confirm that Tadalafil treatment restored all the biological markers to the normal and its involvement in mitochondrial mediated death apoptosis pathway along with inhibition of inflammatory markers.
Published: 2019

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