49 results on '"Struillou, Xavier"'
Search Results
2. Knowledge and Practice Behaviours of Obstetricians/ Gynecologists and Midwives Concerning Periodontal Health and Pregnancy.
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Bechina, Camille, Bonvillain, Guillaume, Rethore, Gildas, Soueidan, Assem, Winer, Norbert, Maitre, Yoann, and Struillou, Xavier
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MIDWIVES ,MEDICAL personnel ,PREGNANCY complications ,GYNECOLOGISTS ,PRENATAL care ,DENTAL hygienists - Abstract
Purpose: The purpose of the present study was to evaluate the level of knowledge of prenatal health professionals concerning the relationship between periodontal diseases and pregnancy complications, as well as their professional implications in the oral health field. Materials and Methods: A questionnaire was distributed to obstetricians/gynecologists, interns specialised in obstetrics/ gynecology, midwives, and student midwives at Loire Atlantique and Vendée hospitals (France). The questionnaire included 5 sociodemographic questions and 14 questions regarding the level of knowledge about the relationship between periodontal diseases and pregnancy complications as well as the professionals' level of involvement in oral health care. Results: Twenty-three obstetricians/gynecologists and 55 midwives responded to the questionnaire. Preterm delivery and chorioamnionitis were the most frequently mentioned complications of pregnancy, whereas the risk of pre-eclampsia was rarely mentioned. Half of the professionals said they were aware of the oral manifestations of pregnancy. Gingivitis and an increased risk of caries were the most frequently mentioned items, whereas epulis was the least frequently mentioned item. The level of involvement of prenatal care practitioners in oral health care was limited due to a lack of competence and time. Nevertheless, 64% of the participants discussed the risks of poor oral hygiene with their patients. Conclusion: There is good knowledge among French gynecologists/obstetricians and midwives regarding the oral manifestations of pregnancy. However, there is still a lack of knowledge concerning the links between periodontal diseases and pregnancy complications. The involvement and behaviour of pregnancy professionals in the oral health field is inadequate. The present survey highlights the need to improve the initial and continuing education of obstetricians and midwives on this topic. [ABSTRACT FROM AUTHOR]
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- 2023
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3. The Effectiveness of the Addition of Platelet-Rich Fibrin to Bovine Xenografts in Sinus and Bone Ridge Augmentation: A Systematic Review
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Idiri, Katia, primary, Bandiaky, Octave, additional, Soueidan, Assem, additional, Verner, Christian, additional, Renard, Emmanuelle, additional, and Struillou, Xavier, additional
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- 2023
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4. Injectable Hydrogel Membrane for Guided Bone Regeneration
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Chichiricco, Pauline Marie, primary, Matricardi, Pietro, additional, Colaço, Bruno, additional, Gomes, Pedro, additional, Jérôme, Christine, additional, Lesoeur, Julie, additional, Veziers, Joëlle, additional, Réthoré, Gildas, additional, Weiss, Pierre, additional, Struillou, Xavier, additional, and Le Visage, Catherine, additional
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- 2023
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5. Current Data on Oral Peri-Implant and Periodontal Microbiota and Its Pathological Changes: A Systematic Review
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Gazil, Virginie, primary, Bandiaky, Octave Nadile, additional, Renard, Emmanuelle, additional, Idiri, Katia, additional, Struillou, Xavier, additional, and Soueidan, Assem, additional
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- 2022
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6. GUIDED PERI-IMPLANT AUTOGENOUS SOFT TISSUE GRAFTING: CASE REPORT
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CRAUSTE, Eleonore, primary, Struillou, Xavier, additional, Lanoiselee, Edouard, additional, and CLOITRE, Alexandra, additional
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- 2022
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7. Periodontal Diseases and Adverse Pregnancy Outcomes: Review of Two Decades of Clinical Research.
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Pockpa, Zocko Ange Désiré, Soueidan, Assem, Koffi-Coulibaly, Nadin Thérèse, Limam, Alexandre, Badran, Zahi, and Struillou, Xavier
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PREGNANCY outcomes ,PREMATURE rupture of fetal membranes ,PERIODONTAL disease ,PREGNANCY complications ,MEDICAL research - Abstract
Purpose: The aim of this study was to review the literature and chart the clinical studies that have focused on periodontal diseases and adverse pregnancy outcomes since 1996. Materials and Methods: Medline, Cinahl, and Cochrane databases were searched for original studies focused on pregnancy outcomes and periodontal status in humans. The most recent search was conducted on April 30, 2020. Results: Of the 633 articles identified, 232 articles (n = 119,774 participants) were selected for analysis. The majority of studies highlighted a statistically significant association between periodontal diseases and preterm birth (71 of 111 articles; 63.96%), low birth weight (46 of 64 articles; 71.87%), preterm low birth weight (29 of 49 articles; 59.18%), preeclampsia (31 of 45 articles; 68.89%) and other pregnancy complications, such as preterm, prelabor rupture of membranes (17 of 26 articles; 65.38%). Geographical analysis revealed that clinical studies were conducted in 51 countries, primarily in the United States (42 studies, 18.10%), Brazil (33 studies, 14.22%) and India (25 studies, 10.78%). Irrespective of geographical location, analysis showed various degrees of evidence of a relationship between periodontal diseases and adverse pregnancy outcomes. Conclusion: The majority of the studies found a statistically significant link between periodontal diseases and some complications of pregnancy. The strength of such a link varies according to type of study, type of variable and outcome measure selected. [ABSTRACT FROM AUTHOR]
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- 2021
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8. Prevalence and risk indicators for severe periodontitis in Côte d’Ivoire
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Koffi-Coulibaly, Nadin Thérèse, primary, Pockpa, Zocko Ange Désiré, additional, Mobio, Gnaba Samson, additional, Struillou, Xavier, additional, and Soueidan, Assem, additional
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- 2022
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9. Receptor activator of nuclear factor kappa B (RANK) as a determinant of peri-implantitis
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Rakić Mia, Nikolić-Jakoba Nataša, Struillou Xavier, Petković-Ćurčin Aleksandra, Stamatović Novak, Matić Smiljka, Janković Saša, Aleksić Zoran, Vasilić Đurđa, Leković Vojislav, and Vojvodić Danilo
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receptor activator of nuclear factor-kappa b ,sensitivity and specificity ,dental implantation ,endosseus ,periodontitis ,Medicine (General) ,R5-920 - Abstract
Background/Aim. Peri-implantitis presents inflammatory process that affects soft and hard supporting tissues of osseointegrated implant based on inflammatory osteoclastogenesis. The aim of this study was to investigate whether receptor activator of nuclear factor kappa B (RANK) concentrations in peri-implant crevicular fluid could be associated with clinical parameters that reflect inflammatory nature of peri-implantitis. Methods. The study included 67 patients, 22 with diagnosed peri-implantitis, 22 persons with healthy peri-implant tissues and 23 patients with periodontitis. Clinical parameters from each patient were recorded and samples of peri-implant/gingival crevicular fluid were collected for the enzyme-linked immunosorbent assay (ELISA) analysis. Results. RANK concentration was significantly increased in samples from the patients with periimplantitis when compared to healthy implants (p < 0.0001), where the average levels were 9 times higher. At the same time RANK concentration was significantly higher in periimplantitis than in periodontitis sites (p < 0.0001). In implant patients pocket depths and bleeding on probing values were positively associated with high RANK concentrations (p < 0.0001). Conclusion. These results revealed association of increased RANK concentration in samples of periimplant/ gingival crevicular fluid with peri-implant inflammation and suggests that RANK could be a pathologic determinant of peri-implantitis, thereby a potential parameter in assessment of peri-implant tissue inflammation and a potential target in designing treatment strategies.
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- 2013
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10. CD14 and TNFα single nucleotide polymorphisms are candidates for genetic biomarkers of peri-implantitis
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Rakic, Mia, Petkovic-Curcin, Aleksandra, Struillou, Xavier, Matic, Smiljana, Stamatovic, Novak, and Vojvodic, Danilo
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- 2015
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11. Guided Peri-Implant Autogenous Soft-Tissue Grafting: A Case Report.
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Crauste, Eleonore, Struillou, Xavier, Lanoiselee, Edouard, and Cloitre, Alexandra
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GINGIVAL grafts ,GINGIVAL recession ,COMPUTED tomography ,DENTAL implants ,TRANSPLANTATION of organs, tissues, etc. ,OSSEOINTEGRATION ,PROOF of concept - Abstract
This case report presents a proof of concept for a guided free gingival graft around a dental implant. A 65-year-old man presented to replace teeth Nos. 30 and 31. Once the osseointegration of the 2 implants placed by guided surgery had been achieved, a free gingival graft was indicated. The surgical planning of this graft was performed using cone-beam computerized tomography and arch digital scanning already used for implant placement. The greater palatine foramen and gutter were radiologically located to protect their arterial content. Two surgical guides were designed, one for the palatal donor site and one for the recipient site. The first one served both as an incision guide and as a postoperative protective plate. The procedure was free of adverse events. At the 1-year recall, the average gain in keratinized tissue width was 2.5 mm. This guided surgery could be used in a patient with insufficient amount of keratinized tissue around a posterior implant. For the first time, this procedure makes it possible to (1) anticipate, (2) accelerate, and (3) secure the surgical intervention. This technique can improve the practitioner's operative comfort and potentially the outcomes of free gingival grafts. Further research and clinical studies are needed to validate this protocol and to assess its long-term impact on peri-implant health. [ABSTRACT FROM AUTHOR]
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- 2022
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12. The association of hydrogel and biphasic calcium phosphate in the treatment of dehiscence-type peri-implant defects: an experimental study in dogs
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Struillou, Xavier, Rakic, Mia, Badran, Zahi, Macquigneau, Laure, Colombeix, Caroline, Pilet, Paul, Verner, Christian, Gauthier, Olivier, Weiss, Pierre, and Soueidan, Assem
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- 2013
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13. Combination of bone substitutes and vectors in periodontology and implantology: A systematic review
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LABUSSIERE, Marion, primary, BADRAN, Zahi, additional, RETHORE, Gildas, additional, VERNER, Christian, additional, SOUEIDAN, Assem, additional, and STRUILLOU, Xavier, additional
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- 2021
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14. Treatment of periodontal defects in dogs using an injectable composite hydrogel/biphasic calcium phosphate
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Struillou, Xavier, Boutigny, Hervé, Badran, Zahi, Fellah, Borhane H., Gauthier, Olivier, Sourice, Sophie, Pilet, Paul, Rouillon, Thierry, Layrolle, Pierre, Weiss, Pierre, and Soueidan, Assem
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- 2011
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15. Tooth desensitization with an Er:YAG laser: in vitro microscopical observation and a case report
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Badran, Zahi, Boutigny, Hervé, Struillou, Xavier, Baroth, Serge, Laboux, Olivier, and Soueidan, Assem
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- 2011
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16. Periodontitis as a risk factor for systemic disease: Are microparticles the missing link?
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Badran, Zahi, Struillou, Xavier, Verner, Christian, Clee, Thibaud, Rakic, Mia, Martinez, Maria C., and Soueidan, Assem
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- 2015
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17. Treatment of stage I-III periodontitis-The EFP S3 level clinical practice guideline
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Sanz, Mariano, Herrera, David, Kebschull, Moritz, Chapple, Iain, Jepsen, Søren, Berglundh, Tord, Sculean, Anton, Tonetti, Maurizio S., Merete Aass, Anne, Aimetti, Mario, Kuru, Bahar Eren, Belibasakis, Georgios, Blanco, Juan, Bol‐van den Hil, Ellen, Bostanci, Nagihan, Bozic, Darko, Bouchard, Philippe, Buduneli, Nurcan, Cairo, Francesco, Calciolari, Elena, Carra, Maria Clotilde, Cortellini, Pierpaolo, Cosyn, Jan, D'Aiuto, Francesco, Dannewitz, Bettina, Danser, Monique, Demirel, Korkud, Derks, Jan, Sanctis, Massimo, Dietrich, Thomas, Dörfer, Christof, Dommisch, Henrik, Donos, Nikos, Eaton, Kenneth, Eickholz, Peter, Figuero, Elena, Giannobile, William, Goldstein, Moshe, Graziani, Filippo, Kamposiora, Phophi, Kirkevang, Lise‐Lotte, Kocher, Thomas, Kononen, Eija, Lang, Nicklaus, Lambert, France, Landi, Luca, Melo, Paulo, Loos, Bruno, Lopez, Rodrigo, Lundberg, Pernilla, Machtei, Eli, Madianos, Phoebus, Martín, Conchita, Matesanz, Paula, Meyle, Jörg, Molina, Ana, Montero, Eduardo, Nart, Jose, Needleman, Ian, Nibali, Luigi, Papapanou, Panos, Pilloni, Andrea, Polak, David, Polyzois, Ioannis, Preshaw, Philip, Quirynen, Marc, Ramseier, Christoph, Renvert, Stefan, Salvi, Giovanni, Sanz‐Sánchez, Ignacio, Shapira, Lior, Slot, Dagmar Else, Stavropoulos, Andreas, Struillou, Xavier, Suvan, Jean, Teughels, Wim, Timus, Daniela, Tomasi, Cristiano, Trombelli, Leonardo, Weijden, Fridus, Vassallo, Paula, Walter, Clemens, West, Nicola, Wimmer, Gernot, Kopp, Ina, Brocklehurst, Paul, Wennström, Jan, EFP Workshop Participants and Methodological Consultants, and Surgical clinical sciences
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medicine.medical_specialty ,Consensus ,Health Behavior ,Psychological intervention ,clinical guideline ,grade ,health policy ,oral health ,periodontal therapy ,periodontitis ,stage ,Disease ,03 medical and health sciences ,0302 clinical medicine ,Germany ,Medicine ,Humans ,030212 general & internal medicine ,Intensive care medicine ,Periodontitis ,Health policy ,Modalities ,business.industry ,Dentistry(all) ,030206 dentistry ,Guideline ,Periodontology ,Clinical Practice Guideline ,medicine.disease ,Gingivitis ,Systematic review ,Periodontics ,business - Abstract
BACKGROUND The recently introduced 2017 World Workshop on the classification of periodontitis, incorporating stages and grades of disease, aims to link disease classification with approaches to prevention and treatment, as it describes not only disease severity and extent but also the degree of complexity and an individual's risk. There is, therefore, a need for evidence-based clinical guidelines providing recommendations to treat periodontitis. AIM The objective of the current project was to develop a S3 Level Clinical Practice Guideline (CPG) for the treatment of Stage I-III periodontitis. MATERIAL AND METHODS This S3 CPG was developed under the auspices of the European Federation of Periodontology (EFP), following the methodological guidance of the Association of Scientific Medical Societies in Germany and the Grading of Recommendations Assessment, Development and Evaluation (GRADE). The rigorous and transparent process included synthesis of relevant research in 15 specifically commissioned systematic reviews, evaluation of the quality and strength of evidence, the formulation of specific recommendations and consensus, on those recommendations, by leading experts and a broad base of stakeholders. RESULTS The S3 CPG approaches the treatment of periodontitis (stages I, II and III) using a pre-established stepwise approach to therapy that, depending on the disease stage, should be incremental, each including different interventions. Consensus was achieved on recommendations covering different interventions, aimed at (a) behavioural changes, supragingival biofilm, gingival inflammation and risk factor control; (b) supra- and sub-gingival instrumentation, with and without adjunctive therapies; (c) different types of periodontal surgical interventions; and (d) the necessary supportive periodontal care to extend benefits over time. CONCLUSION This S3 guideline informs clinical practice, health systems, policymakers and, indirectly, the public on the available and most effective modalities to treat periodontitis and to maintain a healthy dentition for a lifetime, according to the available evidence at the time of publication.
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- 2020
18. Periodontal pockets: A potential reservoir for SARS-CoV-2?
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Badran, Zahi, primary, Gaudin, Alexis, additional, Struillou, Xavier, additional, Amador, Gilles, additional, and Soueidan, Assem, additional
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- 2020
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19. Variation of the Cytokine Profiles in Gingival Crevicular Fluid Between Different Groups of Periodontally Healthy Teeth
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Taso, Ervin, primary, Rakic, Mia, additional, Stefanovic, Vladimir, additional, Petković-Curcin, Aleksandra, additional, Stanojevic, Ivan, additional, Djukic, Mirjana, additional, Struillou, Xavier, additional, Vojvodic, Danilo, additional, Banovic, Tatjana, additional, and Kanjevac, Tatjana, additional
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- 2020
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20. Periodontal Diseases and Age-Related Macular Degeneration: Is There a Link? A Review
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Pockpa, Zocko Ange Désiré, primary, Struillou, Xavier, additional, Kone, Dramane, additional, Mobio, Gnaba Samson, additional, Soueidan, Assem, additional, and Badran, Zahi, additional
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- 2019
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21. Periodontal regenerative medicine using mesenchymal stem cells and biomaterials: A systematic review of pre-clinical studies
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PORTRON, Sophie, primary, SOUEIDAN, Assem, additional, MARSDEN, Anne-Claire, additional, RAKIC, Mia, additional, VERNER, Christian, additional, WEISS, Pierre, additional, BADRAN, Zahi, additional, and STRUILLOU, Xavier, additional
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- 2019
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22. Role of good oral hygiene on clinical evolution of rheumatoid arthritis: a randomized study nested in the ESPOIR cohort
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Mariette, Xavier, primary, Perrodeau, Elodie, primary, Verner, Christian, primary, Struillou, Xavier, primary, Picard, Nicolas, primary, Schaeverbeke, Thierry, primary, Constantin, Arnaud, primary, Ravaud, Philippe, primary, and Bouchard, Philippe, primary
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- 2019
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23. In situ photochemical crosslinking of hydrogel membrane for Guided Tissue Regeneration
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Chichiricco, Pauline Marie, primary, Riva, Raphael, additional, Thomassin, Jean-Michel, additional, Lesoeur, Julie, additional, Struillou, Xavier, additional, Le Visage, Catherine, additional, Jérôme, Christine, additional, and Weiss, Pierre, additional
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- 2018
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24. Role of good oral hygiene on clinical evolution of rheumatoid arthritis: a randomized study nested in the ESPOIR cohort.
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Mariette, Xavier, Perrodeau, Elodie, Verner, Christian, Struillou, Xavier, Picard, Nicolas, Schaeverbeke, Thierry, Constantin, Arnaud, Ravaud, Philippe, and Bouchard, Philippe
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CONFIDENCE intervals ,DENTAL scaling ,MOUTHWASHES ,PATHOLOGY ,PERIODONTAL disease ,RHEUMATOID arthritis ,STATISTICAL sampling ,TOOTH care & hygiene ,RANDOMIZED controlled trials ,GRAM-negative anaerobic bacteria - Abstract
Objective There is a relationship between RA and periodontal disease. We aimed to investigate if a good oral hygiene could improve activity of RA. Methods The patients with RA according to ACR/EULAR 2010 criteria and included in the French early arthritis ESPOIR cohort were included in a randomized nested study into: (i) intervention group: general recommendations of good oral hygiene including teeth brushing, daily antiseptic mouthwash and twice a year scaling; and (ii) control group: no intervention. The primary end point was the delta DAS28-ESR. Results Four hundred and seventy-two patients were randomized (238 in intervention and 234 in control). 92/238 from the intervention group accepted the procedure and 81 had a first visit to the dentist. 56% of patients had periodontal disease at baseline. Duration of RA was 9.0±0.7 years. Baseline DAS28-ESR was 2.7±1.3. After a median duration of 24 months, delta DAS28-ESR was −0.17±1.29 and −0.09±1.28 in intervention and control groups, respectively (mean difference (complier average causal effect): −0.37 (95% CI −1.12, 0.37), P = 0.33). In the intervention group, there was a significant decrease of the bacteria involved in the red complex: Porphyromonas gingivalis (P = 0.002), Tannerella forsythia (P = 0.002) and Treponema denticola (P = 0.019). The patients with baseline periodontal disease and those who became negative for one red complex bacterium had a slightly more important decrease of DAS28-ESR. Conclusion Oral hygiene instruction together with regular scaling and polishing of the teeth significantly decreased the load of periodontal pathogens but did not decrease RA activity. This intervention should be tested in patients with earlier RA and more active disease. Trial registration ClinicalTrials.gov, http://clinicaltrials.gov , NCT01831648. [ABSTRACT FROM AUTHOR]
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- 2020
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25. Evaluation of a hydrogel membrane on bone regeneration in furcation periodontal defects in dogs
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STRUILLOU, Xavier, primary, FRUCHET, Aurélien, additional, RAKIC, Mia, additional, BADRAN, Zahi, additional, RETHORE, Gildas, additional, SOURICE, Sophie, additional, FELLAH, Borhane Hakim, additional, LE GUEHENNEC, Laurent, additional, GAUTHIER, Olivier, additional, WEISS, Pierre, additional, and SOUEIDAN, Assem, additional
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- 2018
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26. Twenty Years of Full-Mouth Disinfection: The Past, the Present and the Future
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Pockpa, Ange Désiré, primary, Soueidan, Assem, additional, Louis, Pauline, additional, Coulibaly, Nadin Thérèse, additional, Badran, Zahi, additional, and Struillou, Xavier, additional
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- 2018
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27. Uticaj tipa materijala za plombiranje zuba na koncentraciju interleukina 9 u uzorcima gingivalne sulkusne tečnosti
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Ervin Taso, Karolina Miller, Mia Rakic, Ivan Stanojevic, Milena Jovic, Danilo Vojvodic, Struillou Xavier, Aleksandra Petkovic-Curcin, Milka Gardasevic, Mirjana Đukić, and Vladimir Stefanovic
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0301 basic medicine ,Gingival and periodontal pocket ,medicine.medical_treatment ,Dentistry ,Gingivitis ,0302 clinical medicine ,gingivalna sulkusna tečnost ,gingival cervicular fluid ,dental materials ,Pharmacology (medical) ,Dental Restoration, Permanent ,Orthodontics ,lcsh:R5-920 ,Dental Plaque Index ,Gingival Crevicular Fluid ,Middle Aged ,materijali za punjenje korenskog kanala ,medicine.symptom ,Periodontal Index ,lcsh:Medicine (General) ,Dental restoration ,Adult ,Adolescent ,karijes ,engineering.material ,Dental Caries ,03 medical and health sciences ,Dental Materials ,Young Adult ,stomatognathic system ,medicine ,Humans ,Interleukin 9 ,Gingival sulcus ,Aged ,business.industry ,interleukin-9 ,Interleukin-9 ,030206 dentistry ,cytokines ,Amalgam (dentistry) ,stomatognathic diseases ,Dental Restoration, Temporary ,030104 developmental biology ,Odontoblast ,engineering ,dental caries ,citokini ,zub ,business - Abstract
Background/Aim. Several cytokines and lymphokines (IL1β, ENA78, IL6, TNFα, IL8 and S100A8) are expressed during dental pulp inflammation. Analysis of gingival crevicular fluid (GCF) offers a non-invasive means of studying general host response in oral cavity. Although GCF levels of various mediators could reflect the state of inflammation both in dental pulp and gingiva adjacent to a tooth, GCF samples of those without significant gingivitis could be interpreted as reflection of pulpal process. The aim of this study was to investigate IL9 GCF values in patients with dental caries and to assess possible influence of various dental fillings materials on local IL9 production. Methods. The study group included 90 patients, aged 18-70, with inclusion and exclusion criteria in the prospective clinical study. Of the 6 types of material used for the restoration of prepared cavities, 3 were intended for temporary and 3 for definitive restoration. According to dental fillings weight, all the participants were divided into 3 groups: those with fillings lighter than 0.50 g, those with 0.50-1.00 g, and those with fillings heavier than 1.00 g. Samples were taken from gingival sulcus using the filter paper technique. Clinical parameters were determined by bleeding index, plaque index (Silness-Lou, 0-3), gingival index (0-3), and gingival sulcus depth. Cytokine concentrations were assessed using commercially available cytomix. Results. According to the weight of dental fillings, there was a clear decreament trend of IL9 values meaning that dental defects greater than 1.00 g of dental filling were associated with lower GCF IL9 concentration. The IL9 values correlated with the degree of gingival index and depth of gingival sulcus, being higher with more advanced gingivitis and more pronounced anatomical changes in the tooth edge. Different filling materials exerted various local IL9 responses. Zink polycarbonate cement and amalgam fillings induced a significant and long-lasting local IL9 decrement, while the use of Tetric EvoCeram and GMA-BISK significantly increased IL9 levels. Conclusion. The obtained results indicate that IL9 GCF could be regarded as a measure of odontoblasts' response to the extensity of dental caries. The type of material used for dental fillings could profoundly alter biological function of gingival and pulpal cells. Also, the results obtained in this study suggest that some materials could even enhance wound repair by modulating macrophage activation. Uvod/Cilj. Jedan broj citokina i limfokina (IL1β, ENA78, IL6, TNFα, IL8 I S100A8) izlučuje se tokom upale zubne pulpe. Analiza gingivalne sulkusne tečnosti (gingival crevicular fluid - GCF) omogućava neinvazivno proučavanje opšteg odgovora pacijenta na lokalne promene u usnoj duplji. Iako nivoi GCF mogu da odražavaju stanje upale kako u zubnoj pulpi, tako i u gingivi susednog zuba, uzorci GCF zuba bez značajnijeg gingivitisa mogli bi se tumačiti kao pokazatelji procesa u pulpi. Cilj ovog istraživanja bio je da se ispitaju nivoi IL9 u GCF kod pacijenata sa zubnim karijesom i da se utvrdi eventualni uticaj različitih materijala za zubne ispune na lokalnu proizvodnju IL9. Metode. U studiju je bilo uključeno 90 pacijenata, starih od 18 do 70 godina, uz primenu kriterijuma za uključivanje/isključivanje za prospektivne kliničke studije. Od ukupno šest materijala za punjenje pripremljenih kaviteta, tri je korišćeno za privremenu i tri za trajnu ispunu. Prema težini zubnog ispuna, pacijenti su bili podeljeni na tri grupe: oni sa ispunama lakšim od 0,50 g, sa ispunama od 0,50 do 1,00 g i sa ispunama težim od 1,00 g. Uzorci su uzimani iz gingivalnog sulkusa primenom tehnike filter papira. Korišćeni klinički parametri bili su indeks krvarenja, plak indeks (Silness-Lou, 0-3), gingivalni indeks (0-3) i dubina gingivalnog sulkusa. Koncentracije citokina određene su komercijalnim citomiksom. Rezultati. Težina zubne ispune ukazivala je na tendenciju opadanja vrednosti IL9, što je značilo da je veće oštećenje zuba, sa zubnom ispunom težom od 1,00 g, praćeno nižom koncentracijom IL9 u GCF. Vrednosti IL9 bile su u korelaciji sa stepenom gingivalnog indeksa i dubinom gingivalnog sulkusa, pogotovu u poodmaklom gingivitisu i izraženijim anatomskim promenama ivica zuba. Različite ispune izazivale su različite lokalne sekrecije IL9. Cink-polikarbonatni cement i amalgamska ispuna izazvale su značajan i dugotrajan pad nivoa lokalnog IL9, dok je primena tetrik-evocerama i GMA-BISK znatno povisila nivoe IL9. Zaključak. Rezultati dobijeni u ovoj studiji ukazuju da se IL9 u GCF može koristiti kao mera za reakciju odontoblasta na veličinu karijesa. Tip zubne ispune može da promeni biološku funkciju ćelija gingive i pulpe. Rezultati ove studije, takođe, ukazuju i na to da neke vrste ispuna mogu čak da ubrzaju zarastanje rane modulacijom aktivnosti makrofaga.
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- 2016
28. MMP-9 -1562 C>T (rs3918242) Promoter Polymorphism as a Susceptibility Factor for Multiple Gingival Recessions.
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Perunovic, Neda, Rakic, Mia, Jankovic, Sasa, Aleksic, Zoran, Struillou, Xavier, Cakic, Sasa, Puletic, Miljan, Lekovic, Vojislav, and Milasin, Jelena
- Subjects
GINGIVAL recession ,CONFIDENCE intervals ,FISHER exact test ,GENETIC polymorphisms ,NUCLEOTIDES ,POLYMERASE chain reaction ,RESEARCH funding ,LOGISTIC regression analysis ,PILOT projects ,DATA analysis software ,DESCRIPTIVE statistics ,MATRIX metalloproteinases ,ODDS ratio ,GENOTYPES ,DISEASE risk factors - Abstract
The objective of this pilot study was to investigate the potential role of -1562 C>T single nucleotide polymorphism (SNP) in the promoter region of the matrix metalloproteinase-9 (MMP-9) gene as a risk modulator in the development of multiple gingival recessions (MGRs) in young adults in the Serbian population. The study sample comprised 161 systemically healthy people: 60 with MGRs and 101 controls with healthy periodontal tissues. Genotyping was done using polymerase chain reaction/restriction fragment length polymorphism approach on DNA obtained from buccal swabs. Clinical measurements included vertical recession depth (VRD), clinical attachment level (CAL), keratinized gingival width (KGW), visible plaque index (PI), and bleeding on probing (BOP). Heterozygotes (CT) were significantly more frequent in the MGRs group than in the control group (P = .005) and carriers of the T allele had an approximately threefold increase of MGRs risk. Patients with the CT genotype exhibited significantly higher values of VRD and CAL and significantly lower values of KGW than patients with the wildtype genotype. Associations among different genotypes and periodontal biotypes in the MGRs group remained insignificant because all participants exhibited thin biotype. The -1562 C>T SNP in the promoter region of MMP-9 appears to be a risk factor for MGR development and a potential predictor of more severe clinical phenotype. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
29. Silicon Nitride (Si3N4) Implants: The Future of Dental Implantology?
- Author
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Badran, Zahi, primary, Struillou, Xavier, additional, Hughes, Francis J, additional, Soueidan, Assem, additional, Hoornaert, Alain, additional, and Ide, Mark, additional
- Published
- 2017
- Full Text
- View/download PDF
30. Clinical Performance of Narrow-Diameter Titanium-Zirconium Implants
- Author
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Badran, Zahi, primary, Struillou, Xavier, additional, Strube, Nicolas, additional, Bourdin, David, additional, Dard, Michel, additional, Soueidan, Assem, additional, and Hoornaert, Alain, additional
- Published
- 2017
- Full Text
- View/download PDF
31. MMP-9-1562 C > T (rs3918242) Promoter Polymorphism as a Susceptibility Factor for Multiple Gingival Recessions
- Author
-
Perunović, Neda, Perunović, Neda, Rakić, Mia, Janković, Saša, Aleksić, Zoran, Struillou, Xavier, Čakić, Saša, Puletić, Miljan, Leković, Vojislav, Milašin, Jelena, Perunović, Neda, Perunović, Neda, Rakić, Mia, Janković, Saša, Aleksić, Zoran, Struillou, Xavier, Čakić, Saša, Puletić, Miljan, Leković, Vojislav, and Milašin, Jelena
- Abstract
The objective of this pilot study was to investigate the potential role of-1562 C>T single nucleotide polymorphism (SNP) in the promoter region of the matrix metalloproteinase-9 (MMP-9) gene as a risk modulator in the development of multiple gingival recessions (MGRs) in young adults in the Serbian population. The study sample comprised 161 systemically healthy people: 60 with MGRs and 101 controls with healthy periodontal tissues. Genotyping was done using polymerase chain reaction/restriction fragment length polymorphism approach on DNA obtained from buccal swabs. Clinical measurements included vertical recession depth (VRD), clinical attachment level (CAL), keratinized gingival width (KGW), visible plaque index (PI), and bleeding on probing (BOP). Heterozygotes (CT) were significantly more frequent in the MGRs group than in the control group (P = .005) and carriers of the T allele had an approximately threefold increase of MGRs risk. Patients with the CT genotype exhibited significantly higher values of VRD and CAL and significantly lower values of KGW than patients with the wildtype genotype. Associations among different genotypes and periodontal biotypes in the MGRs group remained insignificant because all participants exhibited thin biotype. The 1562 C>T SNP in the promoter region of MMP-9 appears to be a risk factor for MGR development and a potential predictor of more severe clinical phenotype.
- Published
- 2015
32. Estimation of Bone Loss Biomarkers as a Diagnostic Tool for Peri-Implantitis
- Author
-
Rakic, Mia, primary, Struillou, Xavier, additional, Petkovic-Curcin, Aleksandra, additional, Matic, Smiljana, additional, Canullo, Luigi, additional, Sanz, Mariano, additional, and Vojvodic, Danilo, additional
- Published
- 2014
- Full Text
- View/download PDF
33. Silicon Nitride (Si3N4) Implants: The Future of Dental Implantology?
- Author
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Badran, Zahi, Struillou, Xavier, Hughes, Francis J, Soueidan, Assem, Hoornaert, Alain, and Ide, Mark
- Subjects
DENTAL implants ,SILICON nitride ,ANTIBACTERIAL agents ,DENTAL ceramics ,OSSEOINTEGRATION ,HEALTH outcome assessment - Abstract
For decades titanium has been the preferred material for dental implant fabrication, with mechanical and biological performance resulting in high clinical success rates. These have been further enhanced by incremental development of surface modifications aimed at improving speed and degree of osseointegration and resulting in enhanced clinical treatment options and outcomes. However, increasing demand for metal-free dental restorations has also led to the development of ceramic-based dental implants, such as zirconia. In orthopedics, alternative biomaterials, such as polyetheretherketone or silicon nitride, have been used for implant applications. The latter is potentially of particular interest for oral use as it has been shown to have antibacterial properties. In this article we aim to shed light on this particular biomaterial as a future promising candidate for dental implantology applications, addressing basic specifications required for any dental implant material. In view of available preclinical data, silicon nitride seems to have the essential characteristics to be a candidate for dental implants material. This novel ceramic has a surface with potentially antimicrobial properties, and if this is confirmed in future research, it could be of great interest for oral use. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
34. CD14 and TNFα single nucleotide polymorphisms are candidates for genetic biomarkers of peri-implantitis
- Author
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Rakic, Mia, primary, Petkovic-Curcin, Aleksandra, additional, Struillou, Xavier, additional, Matic, Smiljana, additional, Stamatovic, Novak, additional, and Vojvodic, Danilo, additional
- Published
- 2014
- Full Text
- View/download PDF
35. Receptor activator of nuclear factor kappa B (RANK) as a determinant of peri-implantitis
- Author
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Rakić, Mia, Rakić, Mia, Nikolić-Jakoba, Nataša, Struillou, Xavier, Petković-Ćurčin, Aleksandra, Stamatović, Novak, Matić, Smiljka, Janković, Saša, Aleksić, Zoran, Vasilić, Đurđa, Leković, Vojislav, Vojvodić, Danilo, Rakić, Mia, Rakić, Mia, Nikolić-Jakoba, Nataša, Struillou, Xavier, Petković-Ćurčin, Aleksandra, Stamatović, Novak, Matić, Smiljka, Janković, Saša, Aleksić, Zoran, Vasilić, Đurđa, Leković, Vojislav, and Vojvodić, Danilo
- Abstract
Background/Aim. Peri-implantitis presents inflammatory process that affects soft and hard supporting tissues of osseointegrated implant based on inflammatory osteoclastogenesis. The aim of this study was to investigate whether receptor activator of nuclear factor kappa B (RANK) concentrations in peri-implant crevicular fluid could be associated with clinical parameters that reflect inflammatory nature of peri-implantitis. Methods. The study included 67 patients, 22 with diagnosed peri-implantitis, 22 persons with healthy peri-implant tissues and 23 patients with periodontitis. Clinical parameters from each patient were recorded and samples of peri-implant/gingival crevicular fluid were collected for the enzyme-linked immunosorbent assay (ELISA) analysis. Results. RANK concentration was significantly increased in samples from the patients with periimplantitis when compared to healthy implants (p lt 0.0001), where the average levels were 9 times higher. At the same time RANK concentration was significantly higher in periimplantitis than in periodontitis sites (p lt 0.0001). In implant patients pocket depths and bleeding on probing values were positively associated with high RANK concentrations (p lt 0.0001). Conclusion. These results revealed association of increased RANK concentration in samples of periimplant/ gingival crevicular fluid with peri-implant inflammation and suggests that RANK could be a pathologic determinant of peri-implantitis, thereby a potential parameter in assessment of peri-implant tissue inflammation and a potential target in designing treatment strategies., Uvod/Cilj. Periimplantitis predstavlja inflamatorni proces koji zahvata meko i tvrdo potporno tkivo osteointegrisanog implantata, i zasnovan je na inflamatornoj osteoklastogenezi. Cilj studije bio je da se utvrdi povezanost koncentracije receptora aktivatora nuklearnog faktora kapa-B (RANK), kao glavnog receptora osteoklastnog metabolizma, sa kliničkim parametrima periimplantitisa. Metode. Studija je uključila 67 sistemski zdravih pacijenata (22 sa periimplantitisom, 22 sa zdravim implantatima i 23 sa periodontopatijom). Pacijentima su mereni klinički parametri i uziman je uzorak periimplantne/gingivalne tečnosti za određivanje koncentracije RANK-a ELISA metodom. Rezultati. Koncentracija RANK-a bila je značajno povišena kod periimplantitisa u odnosu na zdrave implantate (p lt 0,0001), gde je srednja vrednost koncentracije bila 9 puta veća. Istovremeno, RANK je bio značajno viši kod periimplantitisa nego kod parodontopatije (p lt 0,0001). U grupi sa implantatima dubina periodontalnog džepa i krvarenje na probu bili su pozitivno udruženi sa visokim vrednostima RANK-a (p lt 0,0001). Zaključak. Rezultati istraživanja pokazuju udruženost povišenosti koncentracije RANK-a sa periimplantnom inflamacijom i navodi na zaključak da bi RANK mogao da bude patološka determinanta periimplantitisa, a time i potencijalni parametar za praćenje inflamacije periimplantnog tkiva i potencijalni cilj za pravljenje terapijskih strategija.
- Published
- 2013
36. Clinical Outcomes After Nonsurgical Periodontal Therapy with an Er:YAG Laser Device: A Randomized Controlled Pilot Study
- Author
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Badran, Zahi, primary, Boutigny, Hervé, additional, Struillou, Xavier, additional, Weiss, Pierre, additional, Laboux, Olivier, additional, and Soueidan, Assem, additional
- Published
- 2012
- Full Text
- View/download PDF
37. Laser-Induced Fluorescence for Subgingival Calculus Detection: Scientific Rational and Clinical Application in Periodontology
- Author
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Badran, Zahi, primary, Demoersman, Julien, additional, Struillou, Xavier, additional, Boutigny, Hervé, additional, Weiss, Pierre, additional, and Soueidan, Assem, additional
- Published
- 2011
- Full Text
- View/download PDF
38. Er:YAG Laser in the Clinical Management of Severe Peri-implantitis: A Case Report
- Author
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Badran, Zahi, primary, Bories, Céline, additional, Struillou, Xavier, additional, Saffarzadeh, Afchine, additional, Verner, Christian, additional, and Soueidan, Assem, additional
- Published
- 2011
- Full Text
- View/download PDF
39. Tooth desensitization with an Er:YAG laser: in vitro microscopical observation and a case report
- Author
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Badran, Zahi, primary, Boutigny, Hervé, additional, Struillou, Xavier, additional, Baroth, Serge, additional, Laboux, Olivier, additional, and Soueidan, Assem, additional
- Published
- 2010
- Full Text
- View/download PDF
40. Experimental Animal Models in Periodontology: A Review
- Author
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Struillou, Xavier, primary, Boutigny, Hervé, additional, Soueidan, Assem, additional, and Layrolle, Pierre, additional
- Published
- 2010
- Full Text
- View/download PDF
41. Variation of the cytokine profiles in gingival crevicular fluid between different groups of periodontally healthy teeth
- Author
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Taso, Ervin, Taso, Ervin, Rakić, Mia, Bajić, Vladimir, Petković-Ćurčin, Aleksandra, Stanojević, Ivan, Đukić, Mirjana, Struillou, Xavier, Vojvodić, Danilo, Banović, Tatjana, Kanjevac, Tatjana, Taso, Ervin, Taso, Ervin, Rakić, Mia, Bajić, Vladimir, Petković-Ćurčin, Aleksandra, Stanojević, Ivan, Đukić, Mirjana, Struillou, Xavier, Vojvodić, Danilo, Banović, Tatjana, and Kanjevac, Tatjana
- Abstract
Profiling of biomarkers of physiological process represents an integrative part in optimisation of diagnostic markers in order to adjust the diagnostic ranges to the potential effects of the local factors such occlusal forces in case of periodontal tissues. The objective of this study was estimation of IL-1β, IL-2, IL-4, IL-5, IL- 6, IL-9, IL-10, IL-12, IL-13, IL-17, IL-22, TNFα and IFNγ concentrations in gingival crevicular fluid samples (GCF) between different groups of teeth. Two hundred fifty-nine systemically healthy non-smokers having at least one vital tooth without restorations, with healthy periodontal tissues, were clinically examined and the GCF sample was retrieved. The cytokine levels were estimated using flow cytometry and compared between central incisors (CI), lateral incisors, canines, first premolars, second premolars, first molars and second molars. Cytokine profiles varied between different groups of teeth with tendency of increase in proinflammatory cytokines from anterior teeth toward molars. Molars might be considered teeth with natural predisposition for faster bone resorption while the adjustment of diagnostic range of periodontal biomarkers for anterior or posterior teeth should be considered within diagnostic context. Cytokine profiles varied between different groups of teeth with tendency of increase in proinflammatory cytokines from anterior teeth toward molars. Molars might be considered teeth with natural predisposition for faster bone resorption while the adjustment of diagnostic range of periodontal biomarkers for anterior or posterior teeth should be considered within diagnostic context., Profilisanje biomarkera fiziološkog procesa predstavlja integrativni deo optimalizacije dijagnostičkih markera, kako bi se dijagnostički rasponi prilagodili potencijalnim uticajima lokalnih faktora poput okluzijskih sila u slučaju parodontalnih tkiva. Cilj ove studije bila je procena koncentracija IL-1b, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12, IL-13, IL-17, IL- 22, TNFα i IFNγ u uzorcima gingivalne tečnosti (GT) kod različitih grupa zuba. Klinički je pregledano dvesta pedeset devet sistemski zdravih nepušača sa najmanje jednim vitalnim zubom bez restauracija, sa zdravim parodontalnim tkivima, i uzet je GT uzorak. Nivoi citokina procenjeni su protočnom citometrijom i upoređeni između centralnih sekutića (CS), bočnih sekutića, očnjaka, prvih i drugih premolara, kao i prvih i drugih kutnjaka. Profil citokina varirao je između različitih grupa zuba sa tendencijom povećanja pro-upalnih citokina od prednjih zuba do kutnjaka. Molari se mogu smatrati zubima sa prirodnom predispozicijom za bržu resorpciju kosti, dok bi podešavanje dijagnostičkog raspona parodontalnih biomarkera za prednje ili zadnje zube trebalo razmotriti unutar dijagnostičkog konteksta.
42. "Use of lasers in the nonsurgical treatment of peri-implantitis: a systematic review of the literature".
- Author
-
Dominique C, Rethore G, Verner C, Alliot C, Soueidan A, and Struillou X
- Abstract
Background: Peri-implantitis is an infectious disease that causes inflammation of the tissue surrounding an implant. The aim of this systematic review of the literature is to assess the effect of the use of lasers in the nonsurgical treatment of peri-implantitis in order to estimate its benefits compared to conventional therapies., Materials and Methods: the review's protocol has been registered on PROSPERO international prospective register. The research strategy was performed according to the PRISMA guidelines. The inclusion criteria were: in vivo studies, written in English, measurements of clinical parameters, minimum follow-up at 6 months and with nonsurgical control group, studies about photodynamic therapy, randomized clinical trial, and clinical trial. Electronic (on Pubmed, Cochrane, LILACS and EPC databases) and manual searches (in articles' referencies) were conducted until July 2021. Risk of bias was assessed for each reference thanks to the Cochrane Collaboration's tool., Results: A total of 12 randomized clinical trials, with a high level of evidence, were selected and investigated in this systematic review. A table summarizes data extracted from these articles. It appears that the parameters improve favorably by using lasers, but without any significant difference., Conclusion: in accordance with the analysis of studies, our results show that laser therapy with specific characteristics allows to obtain beneficial therapeutic effects on wound healing in the short and the medium-term concerning the clinical parameters in the nonsurgical treatment of peri-implantitis. Concerning its long-term usefulness, it has yet to be confirmed. However, its benefits remains limited since the results agree that the effects of the laser are similar to those obtained by using conventional therapy.
- Published
- 2024
- Full Text
- View/download PDF
43. Knowledge and Practice Behaviours of Obstetricians/Gynecologists and Midwives Concerning Periodontal Health and Pregnancy.
- Author
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Bechina C, Bonvillain G, Rethore G, Soueidan A, Winer N, Maitre Y, and Struillou X
- Subjects
- Pregnancy, Female, Infant, Newborn, Humans, Obstetricians, Gynecologists, Surveys and Questionnaires, Attitude of Health Personnel, Midwifery, Obstetrics education, Pregnancy Complications, Periodontal Diseases complications
- Abstract
Purpose: The purpose of the present study was to evaluate the level of knowledge of prenatal health professionals concerning the relationship between periodontal diseases and pregnancy complications, as well as their professional implications in the oral health field., Materials and Methods: A questionnaire was distributed to obstetricians/gynecologists, interns specialised in obstetrics/gynecology, midwives, and student midwives at Loire Atlantique and Vendée hospitals (France). The questionnaire included 5 sociodemographic questions and 14 questions regarding the level of knowledge about the relationship between periodontal diseases and pregnancy complications as well as the professionals' level of involvement in oral health care., Results: Twenty-three obstetricians/gynecologists and 55 midwives responded to the questionnaire. Preterm delivery and chorioamnionitis were the most frequently mentioned complications of pregnancy, whereas the risk of pre-eclampsia was rarely mentioned. Half of the professionals said they were aware of the oral manifestations of pregnancy. Gingivitis and an increased risk of caries were the most frequently mentioned items, whereas epulis was the least frequently mentioned item. The level of involvement of prenatal care practitioners in oral health care was limited due to a lack of competence and time. Nevertheless, 64% of the participants discussed the risks of poor oral hygiene with their patients., Conclusion: There is good knowledge among French gynecologists/obstetricians and midwives regarding the oral manifestations of pregnancy. However, there is still a lack of knowledge concerning the links between periodontal diseases and pregnancy complications. The involvement and behaviour of pregnancy professionals in the oral health field is inadequate. The present survey highlights the need to improve the initial and continuing education of obstetricians and midwives on this topic.
- Published
- 2023
- Full Text
- View/download PDF
44. Papillary Reconstruction using Hyaluronic Acid: A Review.
- Author
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Lieppe T, Alliot C, Verner C, Badran Z, Soueidan A, and Struillou X
- Subjects
- Animals, Humans, Hyaluronic Acid therapeutic use
- Abstract
Purpose: The aim of this review is to analyse the use of hyaluronic acid injection in the interdental space to reconstruct the papilla in animal models and humans., Materials and Methods: Electronic databases were searched up to May 2022, and additional hand searching was performed. The search strategy was implemented according to the PRISMA guidelines. The inclusion criteria were: studies written in English, studies using hyaluronic acid, in vivo studies, studies with a precise number of specimens, case series with ≥6 patients, and studies published after 2010. The risk of bias was assessed for each study that could be evaluated., Results: A total of 19 articles were selected and reviewed in this review. Due to the great heterogeneity of the protocols and materials, comparison between studies was not possible. However, using this technique, the studies found statistically significant improvements in most cases. The filling percentages ranged from 19% to 100%. Regarding patient satisfaction, the few studies that evaluated this parameter found statistically significant results with most patients willing to repeat the experience. Regarding side effects, only two studies reported them. Moreover, the procedure does not seem to be very painful., Conclusion: The results suggest that hyaluronic acid injections seem to be effective in reconstructing papillary volume. However, to date, too few clinical trials with a high level of proof have been conducted on this technique. Future studies will have to work on the size of the sample, the concentration of the product, the number of injections and the injection method.
- Published
- 2022
- Full Text
- View/download PDF
45. Association Between Periodontitis and Preterm Birth in a Cohort of Pregnant Women in Ivory Coast.
- Author
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Pockpa ZAD, Soueidan A, Koffi-Coulibaly NT, Mobio GS, Pere M, Badran Z, and Struillou X
- Subjects
- Female, Infant, Newborn, Pregnancy, Humans, Infant, Low Birth Weight, Cohort Studies, Pregnant Women, Cote d'Ivoire epidemiology, Premature Birth epidemiology, Premature Birth etiology, Periodontitis complications, Periodontitis epidemiology
- Abstract
Purpose: The aim of this study was to investigate the possible association between periodontitis and preterm birth in Ivory Coast., Materials and Methods: A cohort study including 446 volunteers (pregnant women) aged 15-50 years was performed in the Gynecology-Obstetrics Department of the University Hospital Center of Cocody-Abidjan in Ivory Coast. Socioeconomic and periodontal status was obtained during pregnancy. After delivery, obstetric data was collected. Periodontitis was diagnosed according to the new 2018 EFP/AAP classification of Periodontal and Peri-Implant Diseases and Conditions, as follows: a subject presenting with interdental CAL at two non-adjacent teeth or buccal/oral CAL ≥ 3 mm with pocketing > 3 mm was diagnosed with periodontitis. Any birth before the 37th week was considered a preterm birth (PTB)., Results: The prevalence of periodontitis and preterm birth were 59.47% and 18.34%, respectively. Periodontitis was mainly stage 1. PTB was statistically significantly higher in pregnant women with periodontitis compared to women without periodontitis (p = 0.0002). Multivariate analysis showed that periodontitis was associated with PTB (p = 0.0002). Logistic regression showed that periodontitis is a risk factor for preterm birth (OR = 3.62; 95% CI: 1.80-7.31; p = 0.0003)., Conclusion: The results of this study suggest that periodontitis is an additional risk factor for preterm birth in Ivory Coast.
- Published
- 2022
- Full Text
- View/download PDF
46. Effect of Reinforced Oral Hygiene on Periodontally Healthy Dental Students: A Four-year Follow-up Clinical Trial.
- Author
-
Baudrion MC, Bories C, Soueidan A, Enkel B, Struillou X, and Badran Z
- Subjects
- Clinical Trials as Topic, Dental Plaque Index, Follow-Up Studies, Humans, Periodontal Attachment Loss, Periodontal Pocket, Oral Hygiene, Students, Dental
- Abstract
Purpose: In periodontally healthy individuals, mean crevicular depth ranges from 1 to 3 mm. This depth threshold has been used as an indicator to differentiate a physiological dentoalveolar sulcus from a periodontal pocket needing further treatment. Because many studies have shown the important contribution of oral hygiene status to periodontal health, the purpose of this study was to explore the clinical effect of reinforced oral hygiene on the periodontal status of periodontitis-free dental students., Materials and Methods: In our longitudinal observational clinical study, we assessed the periodontal status of healthy individuals attending the dental school by measuring the periodontal pocket depth, bleeding on probing, and plaque index. The follow-up reassessment was carried out four years later at the end of the dental curriculum., Results: The study showed that oral hygiene improvement led to a slight but significant reduction in the mean sulcus depth (-0.049 mm; p<0.0001)., Conclusions: Reinforcement of oral hygiene contributes to the reduction of probing depth even in periodontally healthy patients.
- Published
- 2020
- Full Text
- View/download PDF
47. Silicon Nitride (Si 3 N 4 ) Implants: The Future of Dental Implantology?
- Author
-
Badran Z, Struillou X, Hughes FJ, Soueidan A, Hoornaert A, and Ide M
- Subjects
- Forecasting, Humans, Materials Testing, Surface Properties, Ceramics, Dental Implants trends, Dental Prosthesis Design trends, Silicon Compounds
- Abstract
For decades titanium has been the preferred material for dental implant fabrication, with mechanical and biological performance resulting in high clinical success rates. These have been further enhanced by incremental development of surface modifications aimed at improving speed and degree of osseointegration and resulting in enhanced clinical treatment options and outcomes. However, increasing demand for metal-free dental restorations has also led to the development of ceramic-based dental implants, such as zirconia. In orthopedics, alternative biomaterials, such as polyetheretherketone or silicon nitride, have been used for implant applications. The latter is potentially of particular interest for oral use as it has been shown to have antibacterial properties. In this article we aim to shed light on this particular biomaterial as a future promising candidate for dental implantology applications, addressing basic specifications required for any dental implant material. In view of available preclinical data, silicon nitride seems to have the essential characteristics to be a candidate for dental implants material. This novel ceramic has a surface with potentially antimicrobial properties, and if this is confirmed in future research, it could be of great interest for oral use.
- Published
- 2017
- Full Text
- View/download PDF
48. An in vitro analysis model for investigating the staining effect of various chlorhexidine-based mouthwashes.
- Author
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Kouadio AA, Struillou X, Bories C, Bouler JM, Badran Z, and Soueidan A
- Abstract
Background: There are different mouthwashes containing chlorhexidine in different concentrations, as well as various excipients. Chlorhexidine induce stains or discoloration in teeth and mucous membranes. The aim of this work was to design a model to reproduce in vitro staining associated with the use of different mouthwashes containing chlorhexidine., Material and Methods: We used as substrates of natural teeth and elephant ivory slices. Different incubation baths were conducted over 21 days in culture dishes at 37°C. At the beginning of experiment before incubation (D0) and after 21 days (D21) of incubation with different mouthwashes, pictures of substrates were taken in a standardized manner and an image analysis software was used to analyse and quantify the staining under the various conditions by using the 3 main colours (Red, Green, Blue, RGB)., Results: The results of this work demonstrate a very good reproducibility of the protocol, and secondly, a different expression statistically significant of the primary blue colour. We suggest that for a given concentration of chlorhexidine, the staining effects may vary depending on the excipients used., Conclusions: This replicable model, easy to implement over a relatively short duration, can be used for evaluation of existing mouthwashes, and to test the excipients anti discoloration proposed by manufacturers. Key words: In vitro, chlorhexidine, mouthwashes, dental stain, tooth discoloration., Competing Interests: Conflict of interest statement:All authors disclose any financial and personal relationships with other people or organisations that could inappropriately influence (bias) their work.
- Published
- 2017
- Full Text
- View/download PDF
49. [Peri-implantitis: tools and techniques for disinfecting the implant surface].
- Author
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Bories C, Struillou X, Badran Z, and Soueidan A
- Subjects
- Air Abrasion, Dental, Anti-Bacterial Agents therapeutic use, Dental Plaque prevention & control, Dental Scaling instrumentation, Dental Scaling methods, Humans, Lasers, Oral Hygiene, Peri-Implantitis surgery, Periodontal Debridement instrumentation, Photochemotherapy, Ultrasonics, Decontamination methods, Dental Implants microbiology, Peri-Implantitis therapy, Periodontal Debridement methods
- Published
- 2011
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