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Purpose: Compare tracking groups with cognitive control functions and plasma brain-derived neurotrophic factors concentrations from childhood to adolescence. Methods: This is a prospective study with 3 years of follow-up. At baseline, data from 394 individuals were collected (11.7 y), and data were obtained from 134 adolescents (14.9 y) at the 3-year follow-up. At both time points, anthropometric and maximal oxygen uptake data were collected. Cardiorespiratory fitness (CRF) groups were classified into high or low CRF. At follow-up, cognitive outcomes were collected via the Stroop and Corsi block test; plasma brain-derived neurotrophic factors concentrations were also analyzed. Results: Comparisons demonstrated that maintaining high CRF over 3 years results in shorter reaction time, better inhibitory control, and higher working memory values. Likewise, the group that moved from low to high CRF over 3 years presented better reaction time. Plasma brain-derived neurotrophic factors concentrations were higher for the group that increased its CRF over the 3 years in relation to the low–low group (90.58 pg·mL−1; P =.004). However, after scaling by an allometric approach, differences were only found for reaction time and working memory between high–high and high–low groups. Conclusion: Maintaining high CRF over 3 years was positively related to reaction time and working memory in relation to adolescents that decreased their levels of CRF. [ABSTRACT FROM AUTHOR]

This study examined whether a 3-month mild-exercise intervention could improve executive function in healthy middle-aged and older adults in a randomized control trial. Ultimately, a total of 81 middle-aged and older adults were randomly assigned to either an exercise group or a control group. The exercise group received 3 months of mild cycle exercise intervention (3 sessions/week, 30-50 min/session). The control group was asked to behave as usual for the intervention period. Before and after the intervention, participants did color-word matching Stroop tasks (CWST), and Stroop interference (SI)-related reaction time (RT) was assessed as an indicator of executive function. During the CWST, prefrontal activation was monitored using functional near-infrared spectroscopy (fNIRS). SI-related oxy-Hb changes and SI-related neural efficiency (NE) scores were assessed to examine the underlying neural mechanism of the exercise intervention. Although the mild-exercise intervention significantly decreased SI-related RT, there were no significant effects of exercise intervention on SI-related oxy-Hb changes or SI-related NE scores in prefrontal subregions. Lastly, changes in the effects of mild exercise on NE with advancing age were examined. The 81 participants were divided into two subgroups (younger-aged subgroup [YA], older-aged subgroup [OA], based on median age [68 years.]). Interestingly, SI-related RT significantly decreased, and SI-related NE scores in all ROIs of the prefrontal cortex significantly increased only in the OA subgroup. These results reveal that a long-term intervention of very light-intensity exercise has a positive effect on executive function especially in older adults, possibly by increasing neural efficiency in the prefrontal cortex.

The apnea-hypopnea index (AHI) is the current diagnostic parameter for diagnosing and estimating the severity of obstructive sleep apnea (OSA). It is, however, poorly associated with the main clinical symptom of OSA, excessive daytime sleepiness, and with the often-seen cognitive decline among OSA patients. To better evaluate OSA severity, novel hypoxic load parameters have been introduced that consider the duration and depth of oxygen saturation drops associated with apneas or hypopneas. The aim of this paper was to compare novel hypoxic load parameters and traditional OSA parameters to verbal memory and executive function in OSA patients. A total of 207 adults completed a one-night polysomnography at sleep laboratory and two neuropsychological assessments, the Rey Auditory Verbal Learning Test and Stroop test. Results : Simple linear regression analyses were used to evaluate independent associations between each OSA parameter and cognitive performance. Associations were found between immediate recall and arousal index, hypoxia <90 %, average SpO 2 during sleep, and DesSev100+RevSev100. Total recall was associated with all OSA parameters, and no associations were found with the Stroop test. Subsequently, sex, age, and education were included as covariates in multiple linear regression analyses for each OSA parameter and cognitive performance. The main findings of the study were that average SpO 2 during sleep was a significant predictor of total recall (p <.007, β = −.188) with the regression model explaining 21.2 % of performance variation. Average SpO 2 during sleep was also a significant predictor of immediate recall (p <.022, β = −.171) with the regression model explaining 11.4 % of performance variation. Neither traditional OSA parameters nor novel hypoxic load parameters predicted cognitive performance after adjustment for sex, age, and education. The findings validate that the AHI is not an effective indicator of cognitive performance in OSA and suggest that average oxygen saturation during sleep may be the strongest PSG predictor of cognitive decline seen in OSA. The results also underline the importance of considering age when choosing neurocognitive tests, the importance of including more than one test for each cognitive domain as most tests are not pure measures of a single cognitive factor, and the importance of including tests that cover all cognitive domains as OSA is likely to have diffuse cognitive effects. • The currently used diagnostic tool for obstructive sleep apnea, the apnea-hypopnea index, is not associated with verbal memory and executive function. • Novel hypoxic load parameters are not associated with verbal memory or executive function in obstructive sleep apnea. • Average oxygen saturation during sleep is the strongest predictor of verbal memory in obstructive sleep apnea. [ABSTRACT FROM AUTHOR]

Objective: Chocolate is a popular food that may affect the activity of the autonomic nervous system (ANS). The aim of this study was to determine the effect of a single dose of dark or milk chocolate on ANS cardiac control during rest and mental stress induced by the Stroop test (ST). Methods: Healthy participants, divided into DARK or MILK chocolate groups, ingested corresponding type of chocolate (1 g/kg body weight). They underwent measurement of ANS during relaxation and ST before and 2 h after chocolate consumption. ANS control was assessed by determination of heart rate (HR) and heart rate variability using parameters related to complex autonomic modulation (TP, SDNN) or primary vagal modulation (HFnu, RMSSD). Results: HR was always increased during ST in both groups. Relaxation HR values after chocolate ingestion were higher only in the DARK chocolate group. During ST, values of TP, SDNN and HFnu decreased before and after chocolate ingestion in the DARK group, but only before chocolate ingestion in the MILK group. RMSSD values decreased during ST before and after chocolate ingestion in both groups. Relaxation TP, RMSSD and HFnu values after chocolate ingestion were lower in the DARK but not in the MILK group. Conclusion: The results suggest that even a single dose of milk chocolate attenuates changes in ANS cardiac control induced by mental stress, whereas a single dose of dark chocolate has an activating effect on the heart via modification of ANS cardiac control at rest. Different levels of sugars and cocoa biologically active compounds in the two types of chocolate could explain the observed effects. [ABSTRACT FROM AUTHOR]

While previous research has identified executive functions as predictors of academic performance in school children, similar studies conducted among adults show mixed results. One of the reasons given for executive functions having a limited effect on academic achievements in adulthood is that they are usually fully developed by that time. Since these executive functions are at their peak at that age, the individual differences in these as well as their influence on academic performance in adults are harder to trace. The paper describes a study conducted among 107 university students the goal of which was to find out whether there is any relationship between the adult students' inhibitory control values measured with the Stroop Test and their academic achievements. Although the results indicate a weak correlation between the Stroop Effect and the students' academic performance of low statistical significance, which seems to confirm the outcomes of the previous studies focusing on adults, the study reveals an unexpected statistically significant correlation between the students' grade averages and the number of their incorrect color identifications. This phenomenon appears to be worth pursuing in future research since it suggests the existence of another, relatively quickly measurable, variable possibly reflecting other predictors of academic performance in adults such as a degree of their manifested conscientiousness, their ability to concentrate on an assigned, relatively short, one-off task and their attitude to fulfilling this task. The Stroop Test, despite not being originally designed for this purpose, might thus be used as a simple tool suitable for providing information about these variables via the subject's number of color identification errors. Such information can subsequently inform the activities that educators may include in their curricula to foster conscientiousness and concentration in the students lacking these. [ABSTRACT FROM AUTHOR]

Abstract While previous research has identified executive functions as predictors of academic performance in school children, similar studies conducted among adults show mixed results. One of the reasons given for executive functions having a limited effect on academic achievements in adulthood is that they are usually fully developed by that time. Since these executive functions are at their peak at that age, the individual differences in these as well as their influence on academic performance in adults are harder to trace. The paper describes a study conducted among 107 university students the goal of which was to find out whether there is any relationship between the adult students’ inhibitory control values measured with the Stroop Test and their academic achievements. Although the results indicate a weak correlation between the Stroop Effect and the students’ academic performance of low statistical significance, which seems to confirm the outcomes of the previous studies focusing on adults, the study reveals an unexpected statistically significant correlation between the students’ grade averages and the number of their incorrect color identifications. This phenomenon appears to be worth pursuing in future research since it suggests the existence of another, relatively quickly measurable, variable possibly reflecting other predictors of academic performance in adults such as a degree of their manifested conscientiousness, their ability to concentrate on an assigned, relatively short, one-off task and their attitude to fulfilling this task. The Stroop Test, despite not being originally designed for this purpose, might thus be used as a simple tool suitable for providing information about these variables via the subject’s number of color identification errors. Such information can subsequently inform the activities that educators may include in their curricula to foster conscientiousness and concentration in the students lacking these.

Minimal hepatic encephalopathy (MHE) has a substantial impact on the clinical outcomes and quality of life (QOL) of patients with cirrhosis. However, timely diagnosis and intervention are challenging due to sophisticated diagnostic methods. In this study, 673 healthy controls and 905 patients with cirrhosis were screened, and 660 healthy controls and 757 patients with cirrhosis, divided into the test (292 patients) and validation (465 patients) cohort, were analyzed after screening. A diagnostic model of the Stroop test (Stroop‐CN) was constructed by multivariate linear regression based on the results of healthy controls. The prevalence of MHE and the comparison results with psychometric hepatic encephalopathy score through the Stroop‐CN model were stable in the test and validation cohorts. Moreover, the prevalence of MHE remained significantly higher in patients with worse disease conditions marked as high Child–Pugh grades and the Model for End‐stage Liver Disease and Sodium (MELD‐Na) scores in the test and validation cohort. The EuroQol 5‐D questionnaire revealed that patients with MHE had a worse QOL than those without MHE both in the test and validation cohort. In conclusion, an easy and practical Stroop‐CN model for MHE diagnosis based on the EncephalApp is established. It is found that a considerable number of Chinese patients with cirrhosis experience MHE, which significantly impacts their QOL. [ABSTRACT FROM AUTHOR]

As a widely used mental task for functional near-infrared spectroscopy (fNIRS), the original color–word Stroop task has the advantage of being difficult to habituate, but also the disadvantage of being difficult to understand, especially for children. While the introduction of derived Stroop tasks offers highly promising countermeasures, changes in brain activity during these tests have not been well tested. We investigated the degree of habituation between the original and a derived Stroop task by measuring brain activity to obtain a better fNIRS task design. Fourteen healthy adults participated in the study, and a 10-channel fNIRS device was used. A picture–word Stroop task with lower linguistic conflict than the original was conducted. The original and derived Stroop tests were repeated four times in a 1-week interval. We found that the original Stroop test did not show any significant changes in brain activity with repeated measures; however, brain activity decreased during the derived test. The differences in habituation between the original and derived tests may be due to the differences in the strength of the linguistic conflict. Our findings also highlight the need to consider the effects of habituation when using derived Stroop tasks in repeated measures. [ABSTRACT FROM AUTHOR]

Objective: The Delis-Kaplan Executive Function System (D-KEFS) Color-Word-Interference Test (CWIT; AKA Stroop test) is a widely used measure of processing speed and executive function. While test materials and instructions have been translated to Norwegian, only American age-adjusted norms from D-KEFS are available in Norway. We here develop norms in a sample of 1011 Norwegians between 20 and 85 years. We provide indexes for stability over time and assess demographic adjustments applying the D-KEFS norms. Method: Participants were healthy Norwegian adults from Center for Lifespan Changes in Brain and Cognition (LCBC) (n = 899), the Dementia Disease Initiation (n = 77), and Oslo MCI (n = 35). Using regression-based norming, we estimated linear and non-linear effects of age, education, and sex on the CWIT 1-4 subtests. Stability over time was assessed with intraclass correlation coefficients (ICC). The normative adjustment of the D-KEFS norms was assessed with linear regression models. Results: Increasing age was associated with slower completion on all CWIT subtests in a non-linear fashion (accelerated lowering of performance with older age). Women performed better on CWIT-1&3. Higher education predicted faster completion time on CWIT-3&4. The original age-adjusted norms from D-KEFS did not adjust for sex or education. Furthermore, we observed significant, albeit small effects of age on all CWIT subtests. ICC analyses indicated moderate to good stability over time. Conclusion: We present demographically adjusted regression-based norms and stability indexes for the D-KEFS CWIT subtests. US D-KEFS norms may be inaccurate for Norwegians with high or low educational attainment, especially women. [ABSTRACT FROM AUTHOR]

Mental fatigue (MF) occurs when a demanding cognitive-task is performed over a long period of time, making it difficult to continue daily tasks and maintain balance. The aim of this investigation was to determine whether the Stroop test induces mental fatigue and to examine its effects on static balance. The study is a quasi-experimental design with pre-post testing. Twenty participants (19-44) were included. Static posturography was used to evaluate balance at baseline following a 25-min relaxation period of rest and in the MFC (mental-fatigue condition) following the induction of MF with the Stroop test. The other measurements were the Multidimensional Fatigue Inventory (MFI), Fatigue Severity Scale (FSS), and Visual Analogue Scale (VAS). The study found that mental fatigue significantly increased at MFC compared to baseline, as indicated by MFI (p=.031) and FSS (p=.007) results with moderate effect sizes (d = 0.52, d = 0.67, respectively). Similarly, the study found a statistically significant increase in mental fatigue as measured by VAS results (p=.000, d = 0.95). However, the study did not find any statistically significant impairment in static balance due to mental fatigue in healthy young subjects. The results suggest that the Stroop test can induce mental fatigue, but it does not impair static balance. [ABSTRACT FROM AUTHOR]

(1) Background: The objective of the present study was to analyze the association of physical fitness, specifically lower limb strength, abdominal strength, vertical jump, and grip strength, with cognitive performance, specifically focusing on selective attention and memory in children aged 7 to 12 years. (2) Methods: Two hundred twenty-seven students participated in this study. Pearson correlation was used to analyze potential relationships between the independent variables and dependent variables. (3) Results: In relation to physical fitness, a higher number of abdominal repetitions performed in 30 s showed a significant and positive association with a higher number of correct responses assessed by the Stroop Test. Furthermore, at a functional level, higher grip strength correlated with a greater number of correct responses and a higher average correct response time in the Stroop Test. Additionally, grip strength showed a significant and positive correlation with the number of words recalled assessed by the word recall test. Our key findings showed a significant association of grip strength with the categories of cognitive status, selective attention, and memory. (4) Conclusions: This study reveals that physical fitness levels, especially grip strength and abdominal strength, correlate with selective attention capacity in primary school students. [ABSTRACT FROM AUTHOR]

Introduction and Objectives: Although the Psychometric Hepatic Encephalopathy Score (PHES) remains the gold standard in diagnosing minimal hepatic encephalopathy (MHE), its complexity limits its application in clinical practice. While more convenient tests, such as the Stroop test, Quickstroop, and the 1-min animal naming test (ANT-1), have emerged, they haven't been validated in our setting. Our objective was to validate these tests in our population. Patients and Methods: This multicenter, observational, descriptive, and cross-sectional study was conducted in three hospitals in northeastern Mexico. MHE was defined as a PHES 15 years without a history of overt hepatic encephalopathy. Data regarding sex, age, education, Child-Pugh/MELD-Na scores, etiology of cirrhosis, diabetes, hypertension, obesity, ascites, and clinically significant portal hypertension was collected. Fisher's exact test, Mann-Whitney U test, and receiver operating characteristic (ROC) curves were used for statistical analysis. Results: Of the 121 patients included, 35.5 % were diagnosed with MHE. The presence of MHE was significantly associated with education level, years of study, and scores in the Stroop test, Quickstroop, and ANT-1. The AUROC curves were 77.9 %, 74.6 %, and 72.7 % for the Stroop test, Quickstroop, and ANT-1, respectively. The resulting cut-off points were 218.398 (sensitivity: 74 %; specificity: 74 %), 40.535 (sensitivity: 77 %; specificity: 68 %), and

Background: Minimal hepatic encephalopathy (MHE) is the mildest form of hepatic encephalopathy. One of the neuropsychological tests that detects MHE is the Stroop test (via EncephalApp). The aim was to evaluate the Stroop test for the screening and diagnosis of MHE. Methods: This prospective case–control study was performed at the Clinic for Gastroenterology and Hepatology, University Clinical Center of Serbia, and included patients with cirrhosis and MHE and healthy controls. In all patients, the presence of MHE was confirmed using the animal naming test. The Stroop test was performed on each participant, and the results were compared between the two groups. The test has two components, the “OFF” and “ON” states. Results: A total of 111 participants were included. The median OFF time did not differ between the two groups, 106.3 and 91.4, p > 0.05. However, in patients with MHE, the median values of ON time and total time were significantly higher, with 122.3 vs. 105.3 and 228.0 vs. 195.6, respectively, p < 0.05. Statistical significance between patients and controls in examined parameters was detected in younger participants and the group with higher educational levels. Conclusions: The Stroop test displayed limited sensitivity in Serbian patients. Age and education affect time measurements and test performance.

Stress has a significant mental health problem of the 21st century. The number of people suffering from stress is increasing rapidly. Thus, easy-to-use, inexpensive, and accurate biomarkers are needed to detect stress during its inception. Early detection of stress-related diseases allows people to access health-care services and leads to the development of new therapies. Thus, for the early detection of stress, a biomarker would be beneficial. We aim to find if there are significant differences between stressed and non-stressed groups of participants and which brain region gets impacted during stress. We conducted experiments to acquire EEG signals to identify the most significant brain region that gets affected due to stress. This research investigates if Higuchi Fractal Dimension (HFD) extracted from EEG signals can act as potential stress biomarkers. A gamified mobile application, known as Color Word and Memory Test (CWMT), was developed, inspired by the well-known Stroop Test, to elicit mental stress at two different difficulty levels. A MUSE headband with four EEG sensors (TP9, AF7, AF8, TP10) was used to collect the EEG signals at the two difficulty levels. The Higuchi Fractal Dimension (HFD) was extracted from EEG signals acquired from 32 participants while they were exposed to stress stimuli (using the proposed CWMT application) and we then performed three experimental analyses, i.e., Analysis I, II and III. Analysis I was performed on all the 32 participants performing low and high difficulty tasks on CWMT application. Analysis II was performed on sub-groups of participants. These sub-groups were made based on score obtained by participants while using CWMT application. Analysis II aimed to find the most significantly impacted brain region during stress. For Analysis III, we used the same sub-groups as Analysis II and it aimed to identify any differences between the left and right hemispheres during stress. We conducted the statistical analysis, and p-values were calculated between the two groups (non-stressed and stressed) to detect EEG channels and brain frequency significantly associated with stress. We performed three experimental analyses (Analysis I and II are intra-hemisphere, and analysis III is inter-hemisphere). In Analysis I, we inferred that beta and alpha frequencies from the AF8 region of the brain are affected during stress. In Analysis II, we inferred that beta waves from the AF8 region are a characteristic indicator of stress. In Analysis III, we identified significant differences between the left and right parts of the brain during stress. We found a significant difference (p<0.05) between HFD value in stress and non-stressed groups in the AF8 region. Our results indicated that stressed patients have a significantly higher value of HFD in the frontal areas. [ABSTRACT FROM AUTHOR]

Improper sitting positions are known as the primary reason for back pain and the emergence of musculoskeletal disorders (MSDs) among individuals who spend prolonged time working with computer screens, keyboards, and mice. At the same time, it is well understood that automated technological tools can play an important role in the process of unhealthy habit alteration, so plenty of research efforts are focused on research and technology development (RTD) activities that aim to provide support for the prevention of back pain or the development of MSDs. Here, we report on creating a new resource in support of RTD activities aiming at the automated detection of improper sitting positions. It consists of multimodal multisensory recordings of 100 persons, made with a video recorder, camera, and wrist-attached sensors that capture physiological signals (PPG, EDA, skin temperature), as well as motion sensors (three-axis accelerometer). Our multimodal multisensory dataset (MMD-MSD) opens new opportunities for modeling the body stance (sitting posture and movements), physiological state (stress level, attention, emotional arousal and valence), and performance (success rate on the Stroop test) of people working with a computer. Finally, we demonstrate two use cases: improper neck posture detection from pictures, and task-specific cognitive load detection from physiological signals. [ABSTRACT FROM AUTHOR]

Background: PD causes striatal dopaminergic denervation in a posterior/dorsal to anterior/ventral gradient, leaving motor and associative cortico‐striato‐pallido‐thalamic loops differentially susceptible to hyperdopaminergic effects with treatment. As the choice and titration of symptomatic PD medications are guided primarily by motor symptoms, it is important to understand their cognitive implications. Objective: To investigate the effects of acute dopaminergic medication administration on executive function in Parkinson's disease (PD). Methods: Participants with idiopathic PD were administered the oral Symbol Digit Modalities Test (SDMT; n = 181) and the Stroop test (n = 172) in the off‐medication and "best on" medication states. ANCOVA was used to test for differences between off‐medication and on‐medication scores corrected for age and years of education. Results: After administration of symptomatic medications, scores worsened on the SDMT (F = 11.70, P < 0.001, d = −0.13), improved on the Stroop color (F = 26.89, P < 0.001, d = 0.184), word (F = 6.25, P = 0.013, d = 0.09), and color‐word (F = 13.22, P < 0.001, d = 0.16) test components, and the Stroop difference and ratio‐based interference scores did not significantly change. Longer disease duration correlated with lower scores on the SDMT, Stroop color, word, and color‐word scores; however, longer disease duration and higher levodopa‐equivalents correlated with higher Stroop difference‐based interference scores. Conclusions: Symptomatic medication differentially affects performance on two cognitive tests in PD. After acute treatment, core Stroop measures improved, Stroop interference was unchanged, and SDMT performance worsened, likely reflecting complex changes in processing speed and executive function related to acute treatment. When considering motor symptom therapies in PD, an individual's cognitive demands and expectations, especially regarding executive function, should be considered. [ABSTRACT FROM AUTHOR]

Super multi-view (SMV) display is a promising 3D display technology; however, potential frame loss due to bandwidth-limited video transmission could cause discomfort to viewers. Thus, an evaluation of the acceptable viewing experience will be valuable. This study investigates the effects of frame loss on visual fatigue in SMV display, focusing on quantified frame loss rates and varying frame loss modes. Experiments were conducted with 20 subjects, utilizing the Stroop test through an SMV display system to evaluate the visual fatigue under different frame loss conditions. The results show a rise in visual fatigue as the frame loss rate increases, with two critical thresholds identified. A 4% frame loss rate marks the threshold for significant loss-induced differences, beyond which visual fatigue begins to become significant in loss-induced modes compared to the normal loss-free mode. Subsequently, a 10% frame loss rate marks the threshold for significant mode-dependent differences, beyond which variations appear between different loss-induced modes, with monocular mode inducing more visual fatigue than binocular and dual-view more than single-view. Consequently, the findings advocate for refining the 3D video processing to maintain a frame loss rate below 4% for negligible effect and considering the interactions between different views for less visual fatigue. This research aims to provide insights and guidance for addressing potential challenges in developing and applying SMV display technology. [ABSTRACT FROM AUTHOR]

This research aimed to identify relations of cognitive and power capacities with reactive agility in pubescent boys (n = 55) and girls (n = 46). Cognitive abilities were evaluated by the Stroop test, while the BlazePod system was used to evaluate agility performance conducting 20 yard shuttle and triangle tests of non-reactive (TCODS) and reactive agility (TRAG), respectively. Performance in jumping power was assessed through the squat jump (SJ), countermovement jump (CMJ), and drop jump (DHJ) utilising the Opto Jump system (Microgate, Bolzano, Italy), while sprinting ability over distances of 10 and 20 m was measured using a photocells system. A principal component was extracted from the four Stroop test variables using factor analysis. Forward stepwise multiple regression analysis was conducted separately for boys and girls to evaluate the multivariate relationships among the predictors and the criterion. Among boys, 80% of the TRAG variance was explained (MultipleR = 0.9), with TCODS and SJ as significant predictors (β = 0.53 and −1.01, respectively). For girls, the TCODS was the significant predictor (β = 0.65), explaining 43% of the variance (MultipleR = 0.65). These results show that (i) cognitive abilities measured with the Stroop test were not a reliable tool for predicting TRAG, (ii) jumping power was a significant predictor of TRAG in boys, and (iii) TCODS was a significant predictor of TRAG in girls. The findings indicated that cognitive abilities do not significantly influence reactive agility in pubescent children. It seems that power features have a greater influence on reactive agility, particularly in boys who have more developed motor skills at this age compared to girls. [ABSTRACT FROM AUTHOR]

Background: Stroop Color Word Test (SCWT) is often adopted to evaluate processing of cognitive function or interference. This study addressed whether different indices of Stroop interference (SI) significantly distinguished Chinese-speaking Alzheimer's disease (AD) persons from control counterparts, and whether SCWT interference errors changed in AD persons of different severity. Methods: Forty native speakers of Mandarin Chinese, including 20 AD persons and 20 controls, participated in this study. All of the participants took SCWT, and their performance was computed for eight SI indices. Different conditions, response types, and AD errors were also examined. Results: Our findings revealed significant group differences in terms of raw scores, response types, and most SI scores. We additionally contributed to SCWT performance by AD persons of different severity. SCWT performance of very mild AD persons was slightly impaired in the incongruous condition, while the mildly-demented persons were more severely impaired in all of the conditions. Conclusion: SI indices in the current study are proven to be helpful in distinguishing AD persons from controls. Moreover, dementia exerts a certain impact on AD SCWT performance. It is thus suggested that AD persons be given help with appropriate application of SCWT, and that SCWT interference errors be adopted as a diagnostic tool in future treatment. [ABSTRACT FROM AUTHOR]

Background: Academic staff have different roles which may impose a high mental workolad on them and affect their cognitive function. This study was designed to assess different subscales of mental worklaod and cognitive function in university academic staff. Methods: This was a cross-sectional study on 86 faculty members of Shahid Sadoughi University of Medical Sciences. Stratified sampling was used to select participants from different schools. The participants were divided into basic sciences and clinical faculty members. Mental workload was assessed by National Aeronautics and Space Administration-Task Load Index (NASA-TLX). Cognitive function was assessed by Stroop test. Data were analyzed by SPSS 26 using Shapiro-Wilks test, Student's T-test, Mann Whitney U test, univariate ANOVA, and Kruskal-Wallis test. The level of significance was 0.05. Results: Mean age and work history of the participants was 43.6±8.6 yr. and 11.7±9.1 yr., respectively. Mental workload, especially two aspects of mental demand and performance, was high and it was significantly higher in the participants from school of medicine and among those with executive/administrative responsibilities. From subscales of mental workload, physical demand was significantly higher among clinical than basic sciences faculty members (p<0.05). Among different aspects of cognitive function, only numbers of congruent errors were significantly higher among clinical faculties. Mental workload and cognitive function were not significantly correlated. Conclusion: This study showed a high level of mental workload in university academic staff, especially in clinical faculty members, but this high mental workload did not affect their cognitive function. [ABSTRACT FROM AUTHOR]

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AbstractPurposeMethodsResultsConclusionOff-topic verbosity (OTV) is a tendency towards excessive, off-topic speech and has been linked with age-related deficits in executive functioning, particularly inhibition. However, there are numerous disagreements within the literature on what constitutes OTV, and there is a further lack of investigation into alternative cognitive explanations for the link between inhibition and OTV. The purpose of this study was to investigate the speech characteristics of OTV in young and older adults as well as to examine whether variations in OTV are better explained by diminished executive functioning or processing speed, as measured by the D-KEFS Stroop test.Young adults (n = 65; age 18–28) and older adults (n = 85; age 60–98) completed the D-KEFS Color-Word Interference Test and provided verbal samples of autobiographical episodic and procedural speech. These speech samples were rated on three facets of OTV: tangentiality, egocentrism and quantity of speech.Procedural autobiographical speech was found to best measure age cohort variations in OTV, and higher OTV was associated with poorer Stroop test performance in older adults but not in young adults. In fact, young adults only displayed associations between poorer Stroop performance and a reduction in speech quantity. Finally, processing speed deficits were more associated with increased OTV in older adults than executive functioning.These results provide support for links between age-related cognitive decline and OTV, but the results suggest that processing speed may be more implicated than executive functioning. [ABSTRACT FROM AUTHOR]

Background: Minimal hepatic encephalopathy (MHE) is the mildest form of hepatic encephalopathy. One of the neuropsychological tests that detects MHE is the Stroop test (via EncephalApp). The aim was to evaluate the Stroop test for the screening and diagnosis of MHE. Methods: This prospective case–control study was performed at the Clinic for Gastroenterology and Hepatology, University Clinical Center of Serbia, and included patients with cirrhosis and MHE and healthy controls. In all patients, the presence of MHE was confirmed using the animal naming test. The Stroop test was performed on each participant, and the results were compared between the two groups. The test has two components, the "OFF" and "ON" states. Results: A total of 111 participants were included. The median OFF time did not differ between the two groups, 106.3 and 91.4, p > 0.05. However, in patients with MHE, the median values of ON time and total time were significantly higher, with 122.3 vs. 105.3 and 228.0 vs. 195.6, respectively, p < 0.05. Statistical significance between patients and controls in examined parameters was detected in younger participants and the group with higher educational levels. Conclusions: The Stroop test displayed limited sensitivity in Serbian patients. Age and education affect time measurements and test performance. [ABSTRACT FROM AUTHOR]

Abstract Minimal hepatic encephalopathy (MHE) has a substantial impact on the clinical outcomes and quality of life (QOL) of patients with cirrhosis. However, timely diagnosis and intervention are challenging due to sophisticated diagnostic methods. In this study, 673 healthy controls and 905 patients with cirrhosis were screened, and 660 healthy controls and 757 patients with cirrhosis, divided into the test (292 patients) and validation (465 patients) cohort, were analyzed after screening. A diagnostic model of the Stroop test (Stroop‐CN) was constructed by multivariate linear regression based on the results of healthy controls. The prevalence of MHE and the comparison results with psychometric hepatic encephalopathy score through the Stroop‐CN model were stable in the test and validation cohorts. Moreover, the prevalence of MHE remained significantly higher in patients with worse disease conditions marked as high Child–Pugh grades and the Model for End‐stage Liver Disease and Sodium (MELD‐Na) scores in the test and validation cohort. The EuroQol 5‐D questionnaire revealed that patients with MHE had a worse QOL than those without MHE both in the test and validation cohort. In conclusion, an easy and practical Stroop‐CN model for MHE diagnosis based on the EncephalApp is established. It is found that a considerable number of Chinese patients with cirrhosis experience MHE, which significantly impacts their QOL.

This study aims to assess effects of noise on physicians' stress levels and attention capacities within an emergency department. In this prospective cross-sectional study, 15 physicians from a state hospital emergency department with 300,000 annual visits provided demographics, work factors, and physiologic data. Attention was evaluated through smartphone-based Stroop tests, while noise and heart rates were monitored via smartwatches. Median physician age was 26, with 16 months' emergency department experience. Average sound intensity was 68.80 dB. Despite noise, physicians in green/yellow areas showed increased Stroop scores (p = 0.002). Heart rate responses correlated with noise changes. End-of-shift surveys highlighted physicians' adaptability and resilience to high noise levels. Noisy emergency departments pose health risks to physicians, but noise-related stress did not significantly affect attention, beneficial for patient care. [ABSTRACT FROM AUTHOR]

(1) Background: The objective of the present study was to analyze the association of physical fitness, specifically lower limb strength, abdominal strength, vertical jump, and grip strength, with cognitive performance, specifically focusing on selective attention and memory in children aged 7 to 12 years. (2) Methods: Two hundred twenty-seven students participated in this study. Pearson correlation was used to analyze potential relationships between the independent variables and dependent variables. (3) Results: In relation to physical fitness, a higher number of abdominal repetitions performed in 30 s showed a significant and positive association with a higher number of correct responses assessed by the Stroop Test. Furthermore, at a functional level, higher grip strength correlated with a greater number of correct responses and a higher average correct response time in the Stroop Test. Additionally, grip strength showed a significant and positive correlation with the number of words recalled assessed by the word recall test. Our key findings showed a significant association of grip strength with the categories of cognitive status, selective attention, and memory. (4) Conclusions: This study reveals that physical fitness levels, especially grip strength and abdominal strength, correlate with selective attention capacity in primary school students.

Older people often show auditory temporal processing deficits and speech-in-noise intelligibility difficulties even when their audiogram is clinically normal. The causes of such problems remain unclear. Some studies have suggested that for people with normal audiograms, age-related hearing impairments may be due to a cognitive decline, while others have suggested that they may be caused by cochlear synaptopathy. Here, we explore an alternative hypothesis, namely that age-related hearing deficits are associated with decreased inhibition. For human adults (N = 30) selected to cover a reasonably wide age range (25–59 years), with normal audiograms and normal cognitive function, we measured speech reception thresholds in noise (SRTNs) for disyllabic words, gap detection thresholds (GDTs), and frequency modulation detection thresholds (FMDTs). We also measured the rate of growth (slope) of auditory brainstem response wave-I amplitude with increasing level as an indirect indicator of cochlear synaptopathy, and the interference inhibition score in the Stroop color and word test (SCWT) as a proxy for inhibition. As expected, performance in the auditory tasks worsened (SRTNs, GDTs, and FMDTs increased), and wave-I slope and SCWT inhibition scores decreased with ageing. Importantly, SRTNs, GDTs, and FMDTs were not related to wave-I slope but worsened with decreasing SCWT inhibition. Furthermore, after partialling out the effect of SCWT inhibition, age was no longer related to SRTNs or GDTs and became less strongly related to FMDTs. Altogether, results suggest that for people with normal audiograms, age-related deficits in auditory temporal processing and speech-in-noise intelligibility are mediated by decreased inhibition rather than cochlear synaptopathy. [ABSTRACT FROM AUTHOR]

Introduction: Suicide is a global phenomenon. Psychiatric disorders are estimated to contribute to a large proportion of suicides; however, impulsive suicide is also common. Among the ages of 15–29 years, suicide was the second leading cause of death worldwide and has been hypothesized to have reduced response inhibition and decision-making abilities as contributing factors, which directly relate to impaired executive functioning and suicidal behavior. Aim: This study aimed to study sociodemography, method, and pattern of suicide, and response inhibition in suicide survivors. Material and Methods: A case–control study was designed in a tertiary medical center in Madhya Pradesh using convenient sampling of suicide survivors and controls from the general population over 3 months. Data collection was semi-structured pro forma, and response inhibition was assessed using the Stroop test. Statistical analysis was performed using IBM Statistical Package for the Social Sciences (SPSS) Windows version 25.0. Independent-samples Student’s t-test, Chi-square test, and Mann–Whitney U-test were used for analyzing means of continuous data, nominal data, and ordinal data, respectively. The level of significance was at P < 0.05. Result: A total of 126 suicide survivors and 99 controls were assessed after the end of the study period. Age (mean age for cases 25.4 ± 9.16; controls 23 ± 7.9), gender (F ̴ M), and socioeconomic status were used to match cases and controls. 85.7% of suicide survivors had no history of suicide, but the majority had precipitating factors. Anomic suicide was the most common type, and poisoning was the most common method of suicide. Response inhibition between cases and control was significantly different. Conclusion: The majority of suicide attempts were impulsive in youth, with no gender discrimination. Response inhibition seemed to play a role in a suicide attempt. [ABSTRACT FROM AUTHOR]

Prefrontal cortex activation is attenuated during cognitive tasks in patients with suicidal ideation or major depressive disorder (MDD). However, the apparent relationship between patients with MDD, especially suicide high-risk (SHR) adolescents, and the characteristics of their hemodynamic responses has not yet been elucidated. To investigate this relationship, we recruited 30 patients with MDD aged 13 − 19. Functional near-infrared spectroscopy (fNIRS) data were collected for all patients during a Stroop test. Through a ten-time iterative leave-one-out cross-validation via 1000 iterative random search-based feature selections, we achieved a generalized classification accuracy of 70.3 ± 5.0 % (from min. 63.3 % to max. 76.7 %). From the results of random search-based feature selection, Ch 08 oxy and Ch 09 deoxy were identified as the two most relevant fNIRS channels. This finding implies that these fNIRS channels can be used as neurological biomarkers to distinguish SHR adolescents with MDD from suicide low-risk (SLR) adolescents. In addition, we determined the oxy-Hb channels of the SHR group, except for Ch 01 oxy , Ch 02 oxy , Ch 11 oxy , and Ch 14 oxy , were hyperactivated compared to the SLR group. • fNIRS study on adolescents with major depressive disorder • Classification of suicide high- and low-risk groups using machine learning • Development of fNIRS biomarkers via random search-based feature selection method [ABSTRACT FROM AUTHOR]

Breakfast replenishes glucose homeostasis and provides other micro-nutrients for the normal functioning of the body after a long night at night. Habitually skipping breakfast leads not only to metabolic disturbances but also to neurocognitive impairment. Hence, the current study was carried out to study the effect of skipping breakfast on neurocognitive functions. A 9-item breakfast questionnaire was distributed online to students for identifying habitual breakfast skippers from non-skippers based on inclusion criteria. Random blood glucose was noted and visual and auditory reaction time, critical flicker fusion frequency, and Stroop test were assessed in both groups to assess cognition. Forty one habitual breakfast skippers who met the inclusion criteria showed increased visual reaction time, and auditory reaction time indicating cognitive impairment. A significant reduction in the Stroop test was observed among the non-skipper group when compared to the skipper group. This study suggests that skipping breakfast diminishes neurocognitive functions like problem-solving, planning, judgment, information retention, and reasoning. [ABSTRACT FROM AUTHOR]

Daily life activities commonly include many combinations of dual tasks. Although dual task ability has been studied in healthy young adults, dual task performance in adolescents with idiopathic scoliosis (IS) has not been explored. Our objective in this study was to investigate dual task performance in adolescents with IS. We paired 33 adolescents diagnosed with IS and 33 healthy control participants (age range: 11–17 years) and administered to both groups the Stroop Color and Word test as a measure of cognitive ability, and both the Expanded Timed Up and Go (ETUG) test and the Tandem Gait test as measures of motor tasks. During the motor tasks, we had participants spell five-letter words in reverse and count down by seven from a randomly presented number between 50 and 100 to assess their dual task (cognitive-motor) performance. All cognitive, motor, and dual cognitive-motor test scores differed significantly between the IS and healthy control groups. The time taken to complete all these tasks was longer for participants with IS compared with controls (p <.05). These results revealed diminished performances on dual cognitive-motor tasks among adolescents with IS when compared to peers without IS. Dual task performance is a new research paradigm in the scoliosis rehabilitation field, and it should be further investigated in future studies. [ABSTRACT FROM AUTHOR]

Late-life depression (LLD) is a common and debilitating disorder. Previously, resting-state studies have revealed abnormal functional connectivity (FC) of brain networks in LLD. Since LLD is associated with emotional-cognitive control deficits, the aim of this study was to compare FC of large-scale brain networks in older adults with and without a history of LLD during a cognitive control task with emotional stimuli. Cross-sectional case-control study. Twenty participants diagnosed with LLD and 37 never-depressed adults 60–88 years of age underwent functional magnetic resonance imaging during an emotional Stroop task. Network-region-to-region FC was assessed with seed regions in the default mode, the frontoparietal, the dorsal attention, and the salience networks. FC between salience and sensorimotor network regions and between salience and dorsal attention network regions were reduced in LLD patients compared to controls during the processing of incongruent emotional stimuli. The normally positive FC between these networks were negative in LLD patients and inversely correlated with vascular risk and white matter hyperintensities. Emotional-cognitive control in LLD is associated with aberrant functional coupling between salience and other networks. This expands on the network-based LLD model and proposes the salience network as a target for future interventions. [ABSTRACT FROM AUTHOR]

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How do people learn when to allocate how much cognitive control to which task? According to the Learned Value of Control (LVOC) model, people learn to predict the value of alternative control allocations from features of a situation. This suggests that people may generalize the value of control learned in one situation to others with shared features, even when demands for control are different. This makes the intriguing prediction that what a person learned in one setting could cause them to misestimate the need for, and potentially overexert, control in another setting, even if this harms their performance. To test this prediction, we had participants perform a novel variant of the Stroop task in which, on each trial, they could choose to either name the color (more control-demanding) or read the word (more automatic). Only one of these tasks was rewarded each trial and could be predicted by one or more stimulus features (the color and/or word). Participants first learned colors and then words that predicted the rewarded task. Then, we tested how these learned feature associations transferred to novel stimuli with some overlapping features. The stimulus-task-reward associations were designed so that for certain combinations of stimuli, transfer of learned feature associations would incorrectly predict that more highly rewarded task would be color-naming, even though the actually rewarded task was word-reading and therefore did not require engaging control. Our results demonstrated that participants overexerted control for these stimuli, providing support for the feature-based learning mechanism described by the LVOC model.

Improper sitting positions are known as the primary reason for back pain and the emergence of musculoskeletal disorders (MSDs) among individuals who spend prolonged time working with computer screens, keyboards, and mice. At the same time, it is well understood that automated technological tools can play an important role in the process of unhealthy habit alteration, so plenty of research efforts are focused on research and technology development (RTD) activities that aim to provide support for the prevention of back pain or the development of MSDs. Here, we report on creating a new resource in support of RTD activities aiming at the automated detection of improper sitting positions. It consists of multimodal multisensory recordings of 100 persons, made with a video recorder, camera, and wrist-attached sensors that capture physiological signals (PPG, EDA, skin temperature), as well as motion sensors (three-axis accelerometer). Our multimodal multisensory dataset (MMD-MSD) opens new opportunities for modeling the body stance (sitting posture and movements), physiological state (stress level, attention, emotional arousal and valence), and performance (success rate on the Stroop test) of people working with a computer. Finally, we demonstrate two use cases: improper neck posture detection from pictures, and task-specific cognitive load detection from physiological signals.

This research aimed to identify relations of cognitive and power capacities with reactive agility in pubescent boys (n = 55) and girls (n = 46). Cognitive abilities were evaluated by the Stroop test, while the BlazePod system was used to evaluate agility performance conducting 20 yard shuttle and triangle tests of non-reactive (TCODS) and reactive agility (TRAG), respectively. Performance in jumping power was assessed through the squat jump (SJ), countermovement jump (CMJ), and drop jump (DHJ) utilising the Opto Jump system (Microgate, Bolzano, Italy), while sprinting ability over distances of 10 and 20 m was measured using a photocells system. A principal component was extracted from the four Stroop test variables using factor analysis. Forward stepwise multiple regression analysis was conducted separately for boys and girls to evaluate the multivariate relationships among the predictors and the criterion. Among boys, 80% of the TRAG variance was explained (MultipleR = 0.9), with TCODS and SJ as significant predictors (β = 0.53 and −1.01, respectively). For girls, the TCODS was the significant predictor (β = 0.65), explaining 43% of the variance (MultipleR = 0.65). These results show that (i) cognitive abilities measured with the Stroop test were not a reliable tool for predicting TRAG, (ii) jumping power was a significant predictor of TRAG in boys, and (iii) TCODS was a significant predictor of TRAG in girls. The findings indicated that cognitive abilities do not significantly influence reactive agility in pubescent children. It seems that power features have a greater influence on reactive agility, particularly in boys who have more developed motor skills at this age compared to girls.

• We explored the brain regions activated in a rodent version of the Stroop task. • Our data revealed novel involvement of cortical and striatal regions. • The dorsomedial striatum, infralimbic and retrosplenial cortices are implicated. • These data have implications for people with neurological conditions. The Stroop test is a widely used neuropsychological test measuring attention and conflict resolution, which shows sensitivity across a range of diseases, including Alzheimer's, Parkinson's and Huntington's diseases. A rodent analogue of the Stroop test, the Response-Conflict task (rRCT), allows for systematic investigation of the neural systems underpinning performance in this test. Little is known about the involvement of the basal ganglia in this neural process. The aim of this study was to use the rRCT to determine whether striatal subregions are recruited during conflict resolution processing. To achieve this, rats were exposed to Congruent or Incongruent stimuli in the rRCT and the expression patterns of the immediate early gene Zif268 were analysed throughout cortical, hippocampal and basal ganglia subregions. The results confirmed the previously reported involvement of prefrontal cortical and hippocampal regions, as well as identifying a specific role for the dysgranular (but not granular) retrosplenial cortex in conflict resolution. Finally, performance accuracy correlated significantly with reduced neural activation in the dorsomedial striatum. Involvement of the basal ganglia in this neural process has not previously been reported. These data demonstrate that the cognitive process of conflict resolution requires not only prefrontal cortical regions, but also recruits the dysgranular retrosplenial cortex and the medial region of the neostriatum. These data have implications for understanding the neuroanatomical changes that underpin impaired Stroop performance in people with neurological disorders. [ABSTRACT FROM AUTHOR]

Introduction: Given the wide-ranging involvement of cerebellar activity in motor, cognitive, and affective functions, clinical outcomes resulting from cerebellar damage can be hard to predict. Cerebellar vascular accidents are rare, comprising less than 5% of strokes, yet this rare patient population could provide essential information to guide our understanding of cerebellar function. Methods: To gain insight into which domains are affected following cerebellar damage, we retrospectively examined neuropsychiatric performance following cerebellar vascular accidents in cases registered on a database of patients with focal brain injuries. Neuropsychiatric testing included assessment of cognitive (working memory, language processing, and perceptual reasoning), motor (eye movements and fine motor control), and affective (depression and anxiety) domains. Results: Results indicate that cerebellar vascular accidents are more common in men and starting in the 5th decade of life, in agreement with previous reports. Additionally, in our group of twenty-six patients, statistically significant performance alterations were not detected at the group level an average of 1.3 years following the vascular accident. Marginal decreases in performance were detected in the word and color sub-scales of the Stroop task, the Rey Auditory Verbal Learning Test, and the Lafayette Grooved Pegboard Test. Discussion: It is well established that the acute phase of cerebellar vascular accidents can be life-threatening, largely due to brainstem compression. In the chronic phase, our findings indicate that recovery of cognitive, emotional, and affective function is likely. However, a minority of individuals may suffer significant long-term performance impairments in motor coordination, verbal working memory, and/or linguistic processing. [ABSTRACT FROM AUTHOR]

Soccer is a team sport that requires players to process a significant amount of information quickly and respond with both speed and accuracy to the ever-changing demands of the game. As such, success in soccer depends not only on physical attributes but also on cognitive abilities such as perception and decision-making. The aim of the current study was to investigate the acute effects of caffeine ingestion on Stroop test performance before and after repeated small-sided games (SSG) in professional soccer players. Twelve professional male soccer players (29 ± 4.1 years; 78.1 ± 7.7 kg body mass) participated in this study. A randomized crossover double-blind placebo-controlled trial was used. Caffeine (5 mg.kg−1) or a placebo was ingested 45 min before a protocol consisting of five 5 min SSG with 1 min rest intervals. A computerized version of the colour Stroop test was completed immediately before and after the exercise protocol. During the Stroop test, words appeared on the computer screen in three different ways: (i) neutral words (neutral condition); (ii) correspondent colour (i.e., "red" painted in red; congruent condition), or; (iii) different colour (i.e., "red" painted in green; incongruent condition). The incongruent condition aimed to cause the interference effect, as the colour and the word did not match. Ratings of perceived exertion (RPE) were assessed after each SSG. RPE increased during the five sets of the SSG protocol (p < 0.001), without differences between the caffeine and placebo trials. The soccer-specific exercise protocol promoted a faster response during the Stroop test (two-way ANOVA main effect for SSG protocol: p < 0.05), with no differences in accuracy (p > 0.05). Caffeine ingestion resulted in slower reaction time during the Stroop test during the congruent and neutral trials but not during the incongruent trial (two-way ANOVA main effect for supplementation: p = 0.009, p = 0.045, and p = 0.071, respectively). Accuracy was lower in the caffeine trial in congruent and incongruent trials (p < 0.05 caffeine vs. placebo both on the pre- and post-SSG protocol). In conclusion, a soccer-specific exercise protocol improved the Stroop test performance in professional soccer players, but acute caffeine ingestion (5 mg.kg−1) was detrimental. [ABSTRACT FROM AUTHOR]

We aimed to investigate the attention function, which is a parameter of cognitive functions, at different obstruction types (adenoid and tonsil hypertrophy, adenoid hypertrophy only, tonsillar hypertrophy only, and normal) of oral cavity and nasopharynx, and the relationship between obstruction level, type, and attention (N = 80). To evaluate attention function, Stroop test has been performed. Eighteen-item Quality of Life (OSA-18) and Brouillette Symptom Score questionnaires have been completed with each child's parents. Significant and positive relation has been found between Brouillette Symptom Score, OSA-18 score, and each 5 sections of Stroop test's points. It has been shown that children with adenotonsillar hypertrophy (ATH) are negatively affected in terms of obstructive symptoms and quality of life. At the situation of obstructive pathology, the Stroop test durations are affected negatively. Results are supporting that quality of life and attention parameter are affected negatively at children with ATH. [ABSTRACT FROM AUTHOR]

ObjectiveTo understand how, biologically, the acute event of traumatic brain injury gives rise to a long-term disease, we address the relationship between evolving cortical and subcortical brain damage and measures of functional outcome and cognitive functioning at 6 months after injury.MethodsFor this longitudinal analysis, clinical and MRI data were collected in a tertiary neurointensive care setting in a continuous sample of 157 patients surviving moderate to severe traumatic brain injury between 2000 and 2018. For each patient, we collected T1- and T2-weighted MRI data acutely and at the 6-month follow-up, as well as acute measures of injury severity (Glasgow Coma Scale), follow-up measures of functional impairment (Glasgow Outcome Scale-extended), and, in a subset of patients, neuropsychological measures of attention, executive functions, and episodic memory.ResultsIn the final cohort of 113 subcortical and 92 cortical datasets that survived (blind) quality control, extensive atrophy was observed over the first 6 months after injury across the brain. However, only atrophy within subcortical regions, particularly in the left thalamus, was associated with functional outcome and neuropsychological measures of attention, executive functions, and episodic memory. Furthermore, when brought together in an analytical model, longitudinal brain measurements could distinguish good from bad outcome with 90% accuracy, whereas acute brain and clinical measurements alone could achieve only 20% accuracy.ConclusionDespite great injury heterogeneity, secondary thalamic pathology is a measurable minimum common denominator mechanism directly relating biology to clinical measures of outcome and cognitive functioning, potentially linking the acute event and the longer-term disease of traumatic brain injury.

Although autism spectrum disorder (ASD) is characterized by deficits in cognitive control, our previous work has shown that preparatory, goal-directed cognitive processing (proactive control) may be preserved in children with ASD. We investigated whether proactive control is intact in adolescents and young adults with ASD, as well as how symptoms of ASD (repetitive behaviors) and psychopathology (Depressive, Anxiety, and Attention-Deficit/Hyperactivity Problems) are related to proactive control. Participants were adolescents and young adults with ASD (N = 44) and typical development (TD; N = 44). Proactive control was assessed using a picture-word Stroop paradigm where participants named animals depicted in drawings while ignoring a superimposed written animal word. Interference effects (reaction time (RT) differences between more difficult incongruent trials, where animal pictures and words prompted different responses, and simpler congruent trials, where animal pictures and words prompted the same response) were calculated for two versions of the Stroop Task: a mostly congruent (MC) block, where the majority of trials were congruent, and a mostly incongruent (MI) block, where most trials were incongruent. Proactive control was calculated as the reduction in interference in the MI block in comparison to the MC block. Proactive control did not differ between groups, indicating that proactive control is not impaired in adolescents and young adults with ASD. In ASD, depression symptoms were associated with reduced proactive control. Future research should investigate the effects of interventions targeting depression as well as interventions targeting proactive control processes in individuals with ASD and comorbid depression. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Introduction: Suicide is a global phenomenon. Psychiatric disorders are estimated to contribute to a large proportion of suicides; however, impulsive suicide is also common. Among the ages of 15–29 years, suicide was the second leading cause of death worldwide and has been hypothesized to have reduced response inhibition and decision-making abilities as contributing factors, which directly relate to impaired executive functioning and suicidal behavior. Aim: This study aimed to study sociodemography, method, and pattern of suicide, and response inhibition in suicide survivors. Material and Methods: A case–control study was designed in a tertiary medical center in Madhya Pradesh using convenient sampling of suicide survivors and controls from the general population over 3 months. Data collection was semi-structured pro forma, and response inhibition was assessed using the Stroop test. Statistical analysis was performed using IBM Statistical Package for the Social Sciences (SPSS) Windows version 25.0. Independent-samples Student's t-test, Chi-square test, and Mann–Whitney U-test were used for analyzing means of continuous data, nominal data, and ordinal data, respectively. The level of significance was at P < 0.05. Result: A total of 126 suicide survivors and 99 controls were assessed after the end of the study period. Age (mean age for cases 25.4 ± 9.16; controls 23 ± 7.9), gender (F ~ M), and socioeconomic status were used to match cases and controls. 85.7% of suicide survivors had no history of suicide, but the majority had precipitating factors. Anomic suicide was the most common type, and poisoning was the most common method of suicide. Response inhibition between cases and control was significantly different. Conclusion: The majority of suicide attempts were impulsive in youth, with no gender discrimination. Response inhibition seemed to play a role in a suicide attempt.

Computerized Stroop tasks have proven to be valuable tools in experimental and clinical psychology, providing reliable and reproducible assessments of cognitive processes. This paper presents the Influencer-Based Virtual Reality Stroop Test (IB-VRST), an innovative application that allows users to perform an immersive Stroop test while exposed to various virtual influencers. These influencers are categorized as task-related and non-task-related distractors, and elements of social presence implemented through competitive and collaborative virtual avatars. To validate this application and analyze the effects of these influencers on performance and stress levels, we conducted two experiments where we collected quantitative data using application logs and biometric sensors, and qualitative data using pre- and post-experiment questionnaires and self-reported stress ratings. Results show that IB-VRST successfully creates an immersive and intuitive experience that prompts the Stroop effect. While distractors generally impair performance and increase stress levels, social presence elements generally improve performance and reduce stress, except when participants compete against a more skilled opponent. This study adds to the existing literature by providing a comprehensive examination of the effects of virtual influencing factors on immersive Stroop tasks, thereby supporting the development of more engaging, immersive, and effective virtual Stroop tests.

When viewing familiar stimuli (e.g., common words), processing is highly automatized such that it can interfere with the processing of incompatible sensory information. At least two mechanisms may help mitigate this interference. Early selection accounts posit that attentional processes filter out distracting sensory information to avoid conflict. Alternatively, late selection accounts hold that all sensory inputs receive full semantic analysis and that frontal executive mechanisms are recruited to resolve conflict. To test how these mechanisms operate to overcome conflict induced by highly automatized processing, we developed a novel version of the color-word Stroop task, where targets and distractors were simultaneously flickered at different frequencies. We measured the quality of early sensory processing by assessing the amplitude of steady-state visually evoked potentials (SSVEPs) elicited by targets and distractors. We also indexed frontal executive processes by assessing changes in frontal theta oscillations induced by color-word incongruency. We found that target- and distractor-related SSVEPs were not modulated by changes in the level of conflict whereas frontal theta activity increased on high compared to low conflict trials. These results suggest that frontal executive processes play a more dominant role in mitigating cognitive interference driven by the automatic tendency to process highly familiar stimuli.