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526 results on '"Strnad, Vratislav"'

3. DEGRO guideline for personalized radiotherapy of brain metastases and leptomeningeal carcinomatosis in patients with breast cancer

Author

Borm, Kai J., Behzadi, Sophie T., Hörner-Rieber, Juliane, Krug, David, Baumann, Rene, Corradini, Stefanie, Duma, Marciana Nona, Dunst, Jürgen, Fastner, Gerd, Feyer, Petra, Fietkau, Rainer, Haase, Wulf, Harms, Wolfgang, Hehr, Thomas, Matuschek, Christiane, Piroth, Marc D., Schmeel, Leonard Christopher, Souchon, Rainer, Strnad, Vratislav, Budach, Wilfried, and Combs, Stephanie E.

Published
2024
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12. Brachytherapy

Author

Strnad, Vratislav, Kaidar-Person, Orit, editor, Meattini, Icro, editor, and Poortmans, Philip, editor

Published
2022
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19. Outcomes of I-125 Low-Dose-Rate Brachytherapy in Patients with Localized Prostate Cancer: A Comprehensive Analysis from a Specialized Tertiary Referral Center.

Author

Schubert, Philipp, Strnad, Vratislav, Höfler, Daniel, Schweizer, Claudia, Putz, Florian, Lotter, Michael, Kreppner, Stephan, Karius, Andre, Fietkau, Rainer, and Merten, Ricarda

Subjects
*LOW dose rate brachytherapy, *PROSTATE cancer patients, *TUMOR treatment, *TREATMENT effectiveness, *PATIENT reported outcome measures, *PROSTATE cancer
Abstract

Low-dose-rate (LDR) brachytherapy with I-125 seeds is one of the most common primary tumor treatments for low-risk and low-intermediate-risk prostate cancer. This report aimed to present an analysis of single-institution long-term results. We analyzed the treatment outcomes of 119 patients with low- and intermediate-risk prostate cancer treated with LDR brachytherapy at our institution between 2014 and 2020. The analysis focused on biochemical recurrence rates (BRFS), overall survival (OS), cumulative local recurrence rate (CLRR), and the incidence of acute and late toxicities. Patient-reported quality of life measures were also evaluated to provide a holistic view on the treatment's impact. The median follow-up period was 46 months. CLRR was 3.3% (4/119), five-year BRFS was 87%, and the five-year OS rate was 95%. Dysuria was the most common acute urinary toxicity, reported in 26.0% of patients as grade 1 and 13.4% as grade 2. As a late side effect, 12.6% of patients experienced mild dysuria. Sexual dysfunction persisted in 6.7% of patients as grade 1, 7.5% as grade 2, and 10.0% as grade 3. LDR brachytherapy in patients with prostate cancer is an effective treatment, with favorable clinical outcomes and manageable toxicity. The low CLRR and high OS rates, as well as low incidence of severe side effects, support the continued use of LDR brachytherapy as a primary treatment modality for localized prostate cancer. [ABSTRACT FROM AUTHOR]

Published
2024
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22. The use of bolus in postmastectomy radiation therapy for breast cancer: A systematic review

Author

Dahn, Hannah M., Boersma, Liesbeth J., de Ruysscher, Dirk, Meattini, Icro, Offersen, Birgitte V., Pignol, Jean-Philippe, Aristei, Cynthia, Belkacemi, Yazid, Benjamin, Dori, Bese, Nuran, Coles, Charlotte E., Franco, Pierfrancesco, Ho, Alice, Hol, Sandra, Jagsi, Reshma, Kirby, Anna M., Marrazzo, Livia, Marta, Gustavo N., Moran, Meena S., Nichol, Alan M., Nissen, Henrik D., Strnad, Vratislav, Zissiadis, Yvonne E., Poortmans, Philip, and Kaidar-Person, Orit

Published
2021
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24. Salvage Mastectomy Versus Second Conservative Treatment for Second Ipsilateral Breast Tumor Event: A Propensity Score-Matched Cohort Analysis of the GEC-ESTRO Breast Cancer Working Group Database

Author

Hannoun-Levi, Jean-Michel, Gal, Jocelyn, Van Limbergen, Erik, Chand, Marie-Eve, Schiappa, Renaud, Smanyko, Viktor, Kauer-Domer, Daniela, Pasquier, David, Lemanski, Claire, Racadot, Séverine, Houvenaeghel, Gilles, Guix, Benjamin, Belliere-Calandry, Aurélie, Loessl, Kristina, Polat, Bulent, Gutierrez, Cristina, Galalae, Razvan, Polgar, Csaba, and Strnad, Vratislav

Published
2021
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25. Exclusive endocrine therapy or partial breast irradiation for women aged ≥70 years with luminal A-like early stage breast cancer (NCT04134598 – EUROPA): Proof of concept of a randomized controlled trial comparing health related quality of life by patient reported outcome measures

Author

Meattini, Icro, Poortmans, Philip M.P., Marrazzo, Livia, Desideri, Isacco, Brain, Etienne, Hamaker, Marije, Lambertini, Matteo, Miccinesi, Guido, Russell, Nicola, Saieva, Calogero, Strnad, Vratislav, Visani, Luca, Kaidar-Person, Orit, and Livi, Lorenzo

Published
2021
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31. Estimating follow‐up CTs from geometric deformations of catheter implants in interstitial breast brachytherapy: A feasibility study using electromagnetic tracking

Author

Dürrbeck, Christopher, primary, Schulz, Moritz, additional, Pflaum, Leonie, additional, Kallis, Karoline, additional, Geimer, Tobias, additional, Abu‐Hossin, Nadin, additional, Strnad, Vratislav, additional, Maier, Andreas, additional, Fietkau, Rainer, additional, and Bert, Christoph, additional

Published
2023
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33. 596: The utilisation of brachytherapy in Europe – A BrachyHERO survey

Author

Johansen, Jacob G., Jürgenliemk-Schulz, Ina-Maria, Haddad, Hathal, Hannoun-Levi, Jean-Michel, Hellebust, Taran, Guix, Benjamin, Lössl, Kristina, Pieters, Bradley R., Rao, Christopher, Strnad, Vratislav, Sturdza, Alina E., Tagliaferri, Luca, Takácsi-Nagy, Zoltán, Villafranca, Elena, Wojcieszek, Piotr, Rembielak, Agata, and Niehoff, Peter

Published
2024
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37. External-Beam-Accelerated Partial-Breast Irradiation Reduces Organ-at-Risk Doses Compared to Whole-Breast Irradiation after Breast-Conserving Surgery

Author

Ott, Oliver J., primary, Stillkrieg, Wilhelm, additional, Lambrecht, Ulrike, additional, Schweizer, Claudia, additional, Lamrani, Allison, additional, Sauer, Tim-Oliver, additional, Strnad, Vratislav, additional, Bert, Christoph, additional, Hack, Carolin C., additional, Beckmann, Matthias W., additional, and Fietkau, Rainer, additional

Published
2023
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39. Data from Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer

Author

Ruiz-Fernández de Córdoba, Borja, primary, Moreno, Haritz, primary, Valencia, Karmele, primary, Perurena, Naiara, primary, Ruedas, Pablo, primary, Walle, Thomas, primary, Pezonaga-Torres, Alberto, primary, Hinojosa, Juan, primary, Guruceaga, Elisabet, primary, Pineda-Lucena, Antonio, primary, Abengózar-Muela, Marta, primary, Cochonneau, Denis, primary, Zandueta, Carolina, primary, Martínez-Canarias, Susana, primary, Teijeira, Álvaro, primary, Ajona, Daniel, primary, Ortiz-Espinosa, Sergio, primary, Morales, Xabier, primary, Ortiz de Solórzano, Carlos, primary, Santisteban, Marta, primary, Ramos-García, Luis I., primary, Guembe, Laura, primary, Strnad, Vratislav, primary, Heymann, Dominique, primary, Hervás-Stubbs, Sandra, primary, Pío, Rubén, primary, Rodríguez-Ruiz, María E., primary, de Andrea, Carlos E., primary, Vicent, Silvestre, primary, Melero, Ignacio, primary, Lecanda, Fernando, primary, and Martínez-Monge, Rafael, primary

Published
2023
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40. Supplementary Data from Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer

Author

Ruiz-Fernández de Córdoba, Borja, primary, Moreno, Haritz, primary, Valencia, Karmele, primary, Perurena, Naiara, primary, Ruedas, Pablo, primary, Walle, Thomas, primary, Pezonaga-Torres, Alberto, primary, Hinojosa, Juan, primary, Guruceaga, Elisabet, primary, Pineda-Lucena, Antonio, primary, Abengózar-Muela, Marta, primary, Cochonneau, Denis, primary, Zandueta, Carolina, primary, Martínez-Canarias, Susana, primary, Teijeira, Álvaro, primary, Ajona, Daniel, primary, Ortiz-Espinosa, Sergio, primary, Morales, Xabier, primary, Ortiz de Solórzano, Carlos, primary, Santisteban, Marta, primary, Ramos-García, Luis I., primary, Guembe, Laura, primary, Strnad, Vratislav, primary, Heymann, Dominique, primary, Hervás-Stubbs, Sandra, primary, Pío, Rubén, primary, Rodríguez-Ruiz, María E., primary, de Andrea, Carlos E., primary, Vicent, Silvestre, primary, Melero, Ignacio, primary, Lecanda, Fernando, primary, and Martínez-Monge, Rafael, primary

Published
2023
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41. Supplementary Figure from Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer

Author

Ruiz-Fernández de Córdoba, Borja, primary, Moreno, Haritz, primary, Valencia, Karmele, primary, Perurena, Naiara, primary, Ruedas, Pablo, primary, Walle, Thomas, primary, Pezonaga-Torres, Alberto, primary, Hinojosa, Juan, primary, Guruceaga, Elisabet, primary, Pineda-Lucena, Antonio, primary, Abengózar-Muela, Marta, primary, Cochonneau, Denis, primary, Zandueta, Carolina, primary, Martínez-Canarias, Susana, primary, Teijeira, Álvaro, primary, Ajona, Daniel, primary, Ortiz-Espinosa, Sergio, primary, Morales, Xabier, primary, Ortiz de Solórzano, Carlos, primary, Santisteban, Marta, primary, Ramos-García, Luis I., primary, Guembe, Laura, primary, Strnad, Vratislav, primary, Heymann, Dominique, primary, Hervás-Stubbs, Sandra, primary, Pío, Rubén, primary, Rodríguez-Ruiz, María E., primary, de Andrea, Carlos E., primary, Vicent, Silvestre, primary, Melero, Ignacio, primary, Lecanda, Fernando, primary, and Martínez-Monge, Rafael, primary

Published
2023
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43. Late side-effects and cosmetic results of accelerated partial breast irradiation with interstitial brachytherapy versus whole-breast irradiation after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: 5-year results of a randomised, controlled, phase 3 trial

Author

Polgár, Csaba, Ott, Oliver J, Hildebrandt, Guido, Kauer-Dorner, Daniela, Knauerhase, Hellen, Major, Tibor, Lyczek, Jaroslaw, Guinot, José Luis, Dunst, Jürgen, Miguelez, Cristina Gutierrez, Slampa, Pavel, Allgäuer, Michael, Lössl, Kristina, Polat, Bülent, Kovács, György, Fischedick, Arnt-René, Fietkau, Rainer, Resch, Alexandra, Kulik, Anna, Arribas, Leo, Niehoff, Peter, Guedea, Ferran, Schlamann, Annika, Pötter, Richard, Gall, Christine, Uter, Wolfgang, and Strnad, Vratislav

Published
2017
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46. Accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy compared with whole-breast irradiation with boost for early breast cancer: 10-year results of a GEC-ESTRO randomised, phase 3, non-inferiority trial

Author

Strnad, Vratislav, primary, Polgár, Csaba, additional, Ott, Oliver J, additional, Hildebrandt, Guido, additional, Kauer-Dorner, Daniela, additional, Knauerhase, Hellen, additional, Major, Tibor, additional, Łyczek, Jarosław, additional, Guinot, Jose Luis, additional, Gutierrez Miguelez, Cristina, additional, Slampa, Pavel, additional, Allgäuer, Michael, additional, Lössl, Kristina, additional, Polat, Bülent, additional, Fietkau, Rainer, additional, Schlamann, Annika, additional, Resch, Alexandra, additional, Kulik, Anna, additional, Arribas, Leo, additional, Niehoff, Peter, additional, Guedea, Ferran, additional, Dunst, Jürgen, additional, Gall, Christine, additional, and Uter, Wolfgang, additional

Published
2023
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47. GEC-ESTRO multicenter phase 3-trial: Accelerated partial breast irradiation with interstitial multicatheter brachytherapy versus external beam whole breast irradiation: Early toxicity and patient compliance

Author

Ott, Oliver J., Strnad, Vratislav, Hildebrandt, Guido, Kauer-Dorner, Daniela, Knauerhase, Hellen, Major, Tibor, Łyczek, Jaroslaw, Guinot, José Luis, Dunst, Jürgen, Miguelez, Cristina Gutierrez, Slampa, Pavel, Allgäuer, Michael, Lössl, Kristina, Polat, Bülent, Kovács, György, Fischedick, Arnt-René, Wendt, Thomas G., Fietkau, Rainer, Kortmann, Rolf-Dieter, Resch, Alexandra, Kulik, Anna, Arribas, Leo, Niehoff, Peter, Guedea, Ferran, Schlamann, Annika, Pötter, Richard, Gall, Christine, Malzer, Martina, Uter, Wolfgang, and Polgár, Csaba

Published
2016
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48. 5-year results of accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy versus whole-breast irradiation with boost after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: a randomised, phase 3, non-inferiority trial

Author

Strnad, Vratislav, Ott, Oliver J, Hildebrandt, Guido, Kauer-Dorner, Daniela, Knauerhase, Hellen, Major, Tibor, Lyczek, Jaroslaw, Guinot, Jose Luis, Dunst, Jürgen, Miguelez, Cristina Gutierrez, Slampa, Pavel, Allgäuer, Michael, Lössl, Kristina, Polat, Bülent, Kovács, György, Fischedick, Arnt-René, Wendt, Thomas G, Fietkau, Rainer, Hindemith, Marion, Resch, Alexandra, Kulik, Anna, Arribas, Leo, Niehoff, Peter, Guedea, Fernando, Schlamann, Annika, Pötter, Richard, Gall, Christine, Malzer, Martina, Uter, Wolfgang, and Polgár, Csaba

Published
2016
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49. Localization of reference points in electromagnetic tracking data and their application for treatment error detection in interstitial breast brachytherapy.

Author

Dürrbeck, Christopher, Schuster, Sabrina, Sauer, Birte Christina, Abu‐Hossin, Nadin, Strnad, Vratislav, Fietkau, Rainer, and Bert, Christoph

Subjects
INTERSTITIAL brachytherapy, RADIOISOTOPE brachytherapy, BREAST, IMAGE registration, MAGNETS, MAGNETIC fields, TRAFFIC safety
Abstract

Background: Electromagnetic tracking (EMT) is a promising technology that holds great potential to advance patient‐specific pre‐treatment verification in interstitial brachytherapy (iBT). It allows easy determination of the implant geometry without line‐of‐sight restrictions and without dose exposure to the patient. What it cannot provide, however, is a link to anatomical landmarks, such as the exit points of catheters or needles on the skin surface. These landmarks are required for the registration of EMT data with other imaging modalities and for the detection of treatment errors such as incorrect indexer lengths, and catheter or needle shifts. Purpose: To develop an easily applicable method to detect reference points in the positional data of the trajectory of an EMT sensor, specifically the exit points of catheters in breast iBT, and to apply the approach to pre‐treatment error detection. Methods: Small metal objects were attached to catheter fixation buttons that rest against the breast surface to intentionally induce a local, spatially limited perturbation of the magnetic field on which the working principle of EMT relies. This perturbation can be sensed by the EMT sensor as it passes by, allowing it to localize the metal object and thus the catheter exit point. For the proof‐of‐concept, different small metal objects (magnets, washers, and bushes) and EMT sensor drive speeds were used to find the optimal parameters. The approach was then applied to treatment error detection and validated in‐vitro on a phantom. Lastly, the in‐vivo feasibility of the approach was tested on a patient cohort of four patients to assess the impact on the clinical workflow. Results: All investigated metal objects were able to measurably perturb the magnetic field, which resulted in missing sensor readings, that is two data gaps, one for the sensor moving towards the tip end and one when retracting from there. The size of the resulting data gaps varied depending on the choice of gap points used for calculation of the gap size; it was found that the start points of the gaps in both directions showed the smallest variability. The median size of data gaps was ⩽8 mm for all tested materials and sensor drive speeds. The variability of the determined object position was ⩽0.5 mm at a speed of 1.0 cm/s and ⩽0.7 mm at 2.5 cm/s, with an increase up to 2.3 mm at 5.0 cm/s. The in‐vitro validation of the error detection yielded a 100% detection rate for catheter shifts of ≥2.2 mm. All simulated wrong indexer lengths were correctly identified. The in‐vivo feasibility assessment showed that the metal objects did not interfere with the routine clinical workflow. Conclusions: The developed approach was able to successfully detect reference points in EMT data, which can be used for registration to other imaging modalities, but also for treatment error detection. It can thus advance the automation of patient‐specific, pre‐treatment quality assurance in iBT. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Brachytherapy training survey among radiation oncology residents in Europe

Author

Sturdza, Alina Emiliana, primary, Stephanides, Marianne, additional, Jurgenliemk-Schulz, Ina, additional, Eriksen, Jesper Grau, additional, Benstead, Kim, additional, Hoskin, Peter, additional, Vlad, Stefanel, additional, Escande, Alexandre, additional, Corradini, Stefanie, additional, Knoth, Johannes, additional, Westerveld, Henrike, additional, Tagliaferri, Luca, additional, Najari-Jamali, Dina, additional, Konat-Bąska, Katarzyna, additional, Plesinac, Vesna, additional, Tan, Li Tee, additional, Nout, Remi, additional, Strnad, Vratislav, additional, Niehoff, Peter, additional, Pieters, Bradley R., additional, Tanderup, Kari, additional, and Kamrava, Mitchell, additional

Published
2022
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