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Researchers from the National University in Costa Rica conducted a study on the reactivation of latent Brucella infection in mice after treatment with doxycycline and streptomycin. The study found that a specific antibiotic regimen achieved therapeutic levels against Brucella in various tissues with minimal side effects. Despite successful treatment, relapses occurred in all mice after 182 days, suggesting potential mechanisms of bacterial persistence post-treatment. The research, supported by Consejo Nacional de Rectores, provides insights into antibiotic treatment outcomes and bacterial persistence in tissues. [Extracted from the article]

Researchers from China Agricultural University conducted a study on tuberculosis, focusing on the role of outer membrane protein A (OmpA) in antimicrobial resistance in Mycobacteria. The study found that overexpression of OmpA increased aminoglycoside sensitivity in mycobacteria, particularly streptomycin. This research provides valuable insights into antibiotic resistance and potential new strategies for tuberculosis treatment. The study was supported by The National Natural Science Foundation of China and was published in BMC Microbiology. [Extracted from the article]

A study from Yunnan University in Kunming, China, explores a new therapeutic strategy for infectious diseases caused by intracellular multidrug-resistant bacteria. Researchers found that a combination of glabrol and streptomycin effectively targets bacterial inner membrane phospholipids, disrupts arginine biosynthesis, and promotes ROS production, leading to membrane and wall damage. The study concluded that the designed nanoparticles for drug delivery showed significantly higher efficacy in clearing intracellular bacteria compared to the combination alone. This research offers promising insights into combating drug-resistant bacterial infections. [Extracted from the article]

A recent report from Jilin University in the People's Republic of China discusses the findings of a systematic review and network meta-analysis on the treatment options for human brucellosis. The study compared and ranked different antibiotic regimens based on their efficacy and safety. The results showed that doxycycline plus gentamicin, triple therapy, and doxycycline plus streptomycin were the most effective and safe treatments for brucellosis. Rifampicin plus quinolones was considered an alternative therapy, while single therapy and other combinations were not recommended. The study aims to provide clinicians with evidence-based recommendations for brucellosis treatment. [Extracted from the article]

A new report discusses research conducted at the National University of Singapore on the potential synergistic effects of concurrent optical and magnetic stimulation (COMS) for wound healing. The study found that the combination of magnetic fields and light had supra-additive effects on cell proliferation and ATP production, indicating improved mitochondrial respiratory efficiency. However, the presence of streptomycin, an antibiotic, reduced the enhancements in cell proliferation caused by COMS. The researchers concluded that avoiding the use of aminoglycoside antibiotics during COMS therapy is crucial for maintaining clinical efficacy. [Extracted from the article]

Researchers from the National Research Center in Giza, Egypt have conducted a study on tissue engineering for bone regeneration. They prepared nanoceramic powders using a wet-chemical precipitation method and created composite scaffolds by blending alginate, gelatin, and the nanoceramic powders. The scaffolds were then loaded with streptomycin sulfate. The researchers investigated the properties of the scaffolds, including their surface morphology, mechanical strength, swelling, bioactivity, biocompatibility, and drug release. The results showed that the scaffolds with 60% bio-nanoceramic filler and streptomycin sulfate were the most suitable for bone repair. The study suggests that these scaffolds have potential for use in bone regeneration. [Extracted from the article]

A study conducted by Fudan University in Shanghai, China analyzed trends and risk factors for drug resistance in Mycobacterium tuberculosis (M. tuberculosis) in HIV-infected patients with active tuberculosis. The study found that the rates of drug resistance to rifampicin and quinolones in HIV/AIDS patients were high and increasing over the years. Age and a history of previous anti-tuberculosis treatment were identified as the main factors associated with the development of drug resistance in HIV/AIDS patients with tuberculosis. The research provides valuable insights into the understanding of drug resistance in this population. [Extracted from the article]

Researchers at the College of Sciences and Humanities in Tamil Nadu, India have reported new data on the enhanced bioactivity of streptomycin bioconjugated metal nanoparticles against streptomycin-resistant bacillus sp. The study aimed to develop new antimicrobial compounds to combat multidrug resistance in pathogenic organisms. The researchers synthesized silver, gold, and platinum nanoparticles using the rind extract of Garcinia mangostana L. fruit and bioconjugated them with streptomycin. The bioconjugates showed significant antibacterial activity, with the highest activity exhibited by silver nanoparticles. The study also found that the nanoparticles were hemocompatible and did not cause hemolysis. [Extracted from the article]

A recent study conducted at Himachal Pradesh University in Shimla, India, investigated the micellization behavior of streptomycin sulfate, a surface-active drug, in aqueous medium with six amino acids. The study analyzed the thermodynamic aspects using conductivity, density, and speed of sound measurements, as well as UV-Vis spectroscopy. The presence of amino acids was found to enhance the drug's tendency to form micelles, and the study also explored the interactions between amino acids and the drug using UV-Vis spectroscopy. The research concluded that there were significant changes in micropolarity and micelle assembly due to these interactions. This research has been peer-reviewed and provides valuable insights into the behavior of streptomycin sulfate in aqueous amino acid solutions. [Extracted from the article]

A recent study conducted by researchers from Mahasarakham University focused on the antibiofilm and antibacterial activities of lupinifolin, a compound derived from Derris reticulata Craib stem, in combination with protein synthesis inhibitors against methicillin-resistant Staphylococcus aureus (MRSA). The study found that lupinifolin and tetracycline significantly reduced MRSA biofilm formation, while streptomycin and clindamycin tended to enhance biofilm formation. The combination of lupinifolin and streptomycin exhibited synergy in inhibiting MRSA biofilm formation, while the combination of lupinifolin and tetracycline or clindamycin did not show any interaction. These findings suggest that lupinifolin has the potential to enhance antibiofilm activity and reduce MRSA biofilm formation. [Extracted from the article]

Keywords: Amino Acids; Antibiotics; Drugs and Therapies; Health and Medicine; Peptides; Pharmaceuticals; Proteins; Streptomycin Therapy EN Amino Acids Antibiotics Drugs and Therapies Health and Medicine Peptides Pharmaceuticals Proteins Streptomycin Therapy 1534 1534 1 11/06/23 20231110 NES 231110 2023 NOV 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Research findings on antibiotics are discussed in a new report. Keywords for this news article include: Kazi Nazrul University, Antibiotics, Pharmaceuticals, Peptides, Proteins, Amino Acids, Drugs and Therapies, Health and Medicine, Streptomycin Therapy. [Extracted from the article]

The goal of this project was to look at biochemical parameters, trace elements, and inflammatory factors in the acute and chronic stages of brucellosis after treatment with streptomycin and hydroxychloroquine-loaded solid lipid nanoparticles (STR-HCQ-SLN). Keywords: Hamadan; Iran; Asia; Antibiotics; Antiinfectives; Antimalarial Agents; Antirheumatics; Biochemicals; Biochemistry; Brucellosis; Chemicals; Diet and Nutrition; Diseases and Conditions; Drugs and Therapies; Emerging Technologies; Foodborne Diseases and Conditions; Gram-Negative Bacterial Infections; Health and Medicine; Hydroxychloroquine Therapy; Nanoparticles; Nanotechnology; Pharmaceuticals; Streptomycin Therapy; Vitamin D; Vitamins EN Hamadan Iran Asia Antibiotics Antiinfectives Antimalarial Agents Antirheumatics Biochemicals Biochemistry Brucellosis Chemicals Diet and Nutrition Diseases and Conditions Drugs and Therapies Emerging Technologies Foodborne Diseases and Conditions Gram-Negative Bacterial Infections Health and Medicine Hydroxychloroquine Therapy Nanoparticles Nanotechnology Pharmaceuticals Streptomycin Therapy Vitamin D Vitamins 87 87 1 09/11/23 20230914 NES 230914 2023 SEP 14 (NewsRx) -- By a News Reporter-Staff News Editor at Food Weekly News -- New research on Gram-Negative Bacterial Infections - Brucellosis is the subject of a report. [Extracted from the article]

Mumbai, India, Asia, Aminoglycosides Therapy, Antibiotics, Antiinfectives, Biophysics, Drugs and Therapies, Health and Medicine, Neomycin Therapy, Pharmaceuticals, Streptomycin Therapy Keywords: Mumbai; India; Asia; Aminoglycosides Therapy; Antibiotics; Antiinfectives; Biophysics; Drugs and Therapies; Health and Medicine; Neomycin Therapy; Pharmaceuticals; Streptomycin Therapy EN Mumbai India Asia Aminoglycosides Therapy Antibiotics Antiinfectives Biophysics Drugs and Therapies Health and Medicine Neomycin Therapy Pharmaceuticals Streptomycin Therapy 1328 1328 1 09/04/23 20230908 NES 230908 2023 SEP 8 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New research on Drugs and Therapies - Antibiotics is the subject of a report. [Extracted from the article]

Keywords: Actinomycetales Infections; Antibacterials; Antibiotics; Antimicrobials; Drugs and Therapies; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Health and Medicine; Hospitals; Musculoskeletal Diseases and Conditions; Mycobacterium Infections; Mycobacterium Tuberculosis; Osteoarticular Tuberculosis; Pharmaceuticals; Risk and Prevention; Spinal Tuberculosis; Streptomycin Therapy; Surgery; Tuberculosis EN Actinomycetales Infections Antibacterials Antibiotics Antimicrobials Drugs and Therapies Gram-Positive Bacteria Gram-Positive Bacterial Infections Health and Medicine Hospitals Musculoskeletal Diseases and Conditions Mycobacterium Infections Mycobacterium Tuberculosis Osteoarticular Tuberculosis Pharmaceuticals Risk and Prevention Spinal Tuberculosis Streptomycin Therapy Surgery Tuberculosis 1840 1840 1 08/28/23 20230901 NES 230901 2023 AUG 28 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- Investigators publish new report on spinal tuberculosis. For more information on this research see: Topical streptomycin irrigation of lesions to prevent postoperative site infections in spinal tuberculosis: a retrospective analysis. [Extracted from the article]

Because intestinal E. coli isolates exhibit remarkable strain-specific differences, we generated spontaneous StrR mutants of 10 clinical E. coli phylotype B2 strains from patients with IBD, colorectal cancer, and urinary tract infection. Keywords: Antibiotics; Digestive System Diseases and Conditions; Drugs and Therapies; Enterobacteriaceae; Escherichia coli; Genetics; Gram-Negative Bacteria; Health and Medicine; Inflammatory Bowel Disease; Pharmaceuticals; Proteobacteria; Streptomycin Therapy EN Antibiotics Digestive System Diseases and Conditions Drugs and Therapies Enterobacteriaceae Escherichia coli Genetics Gram-Negative Bacteria Health and Medicine Inflammatory Bowel Disease Pharmaceuticals Proteobacteria Streptomycin Therapy 2804 2804 1 07/03/23 20230707 NES 230707 2023 JUL 7 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- New study results on inflammatory bowel disease have been published. [Extracted from the article]

For more information on this research see: Experimental and theoretical studies for corrosion of molybdenum electrode using streptomycin drug in phosphoric acid medium. Keywords: Antibiotics; Chemicals; Drugs and Therapies; Health and Medicine; Heavy Metals; Molybdenum; Orthophosphoric Acid; Pharmaceuticals; Phosphoric Acid; Streptomycin Therapy; Transition Elements EN Antibiotics Chemicals Drugs and Therapies Health and Medicine Heavy Metals Molybdenum Orthophosphoric Acid Pharmaceuticals Phosphoric Acid Streptomycin Therapy Transition Elements 2561 2561 1 04/10/23 20230414 NES 230414 2023 APR 14 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Investigators publish new report on antibiotics. [Extracted from the article]

Keywords: Actinobacteria; Actinomycetales; Actinomycetales Infections; Antibiotics; Antiinfectives; Antituberculosis Agents; Drugs and Therapies; Gram-Positive Asporogenous Rods; Gram-Positive Bacteria; Gram-Positive Rods; Health and Medicine; Hydrazines; Isoniazid; Isoniazid Therapy; Mycobacteria; Mycobacteriaceae; Mycobacterium; Mycobacterium Infections; Mycobacterium Tuberculosis; Mycobacterium tuberculosis; Nicotinic Acid Derivatives; Pharmaceuticals; Streptomycin Therapy; Tuberculosis EN Actinobacteria Actinomycetales Actinomycetales Infections Antibiotics Antiinfectives Antituberculosis Agents Drugs and Therapies Gram-Positive Asporogenous Rods Gram-Positive Bacteria Gram-Positive Rods Health and Medicine Hydrazines Isoniazid Isoniazid Therapy Mycobacteria Mycobacteriaceae Mycobacterium Mycobacterium Infections Mycobacterium Tuberculosis Mycobacterium tuberculosis Nicotinic Acid Derivatives Pharmaceuticals Streptomycin Therapy Tuberculosis 1870 1870 1 03/23/23 20230324 NES 230324 2023 MAR 24 (NewsRx) -- By a News Reporter-Staff News Editor at TB & Outbreaks Week -- New research on Mycobacterium tuberculosis is the subject of a new report. Actinobacteria, Actinomycetales, Actinomycetales Infections, Antibiotics, Antiinfectives, Antituberculosis Agents, Drugs and Therapies, Gram-Positive Asporogenous Rods, Gram-Positive Bacteria, Gram-Positive Rods, Health and Medicine, Hydrazines, Isoniazid, Mycobacteria, Mycobacteriaceae, Mycobacterium, Mycobacterium Infections, Mycobacterium Tuberculosis, Mycobacterium tuberculosis, Nicotinic Acid Derivatives, Isoniazid Therapy, Pharmaceuticals, Streptomycin Therapy, Tuberculosis. [Extracted from the article]

Keywords: Karachi; Pakistan; Asia; Antibiotics; Antiinfectives; Antituberculosis Agents; Drugs and Therapies; Emerging Technologies; Health and Medicine; Hydrazines; Isoniazid; Isoniazid Therapy; Nanoparticles; Nanoprobes; Nanotechnology; Nicotinic Acid Derivatives; Pharmaceuticals; Streptomycin Therapy EN Karachi Pakistan Asia Antibiotics Antiinfectives Antituberculosis Agents Drugs and Therapies Emerging Technologies Health and Medicine Hydrazines Isoniazid Isoniazid Therapy Nanoparticles Nanoprobes Nanotechnology Nicotinic Acid Derivatives Pharmaceuticals Streptomycin Therapy 2268 2268 1 03/23/23 20230310 NES 230310 2023 MAR 10 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- A new study on Nanotechnology - Nanoparticles is now available. Karachi, Pakistan, Asia, Antibiotics, Antiinfectives, Antituberculosis Agents, Drugs and Therapies, Emerging Technologies, Health and Medicine, Hydrazines, Isoniazid Therapy, Nanoparticles, Nanoprobes, Nanotechnology, Nicotinic Acid Derivatives, Pharmaceuticals, Streptomycin Therapy, Isoniazid. [Extracted from the article]

Keywords: Campo Grande; Brazil; South America; Antibiotics; Antiinfectives; Bacterial Infections and Mycoses; Benzamidines; Chloramphenicol; Chloramphenicol Therapy; Diminazene; Drugs and Therapies; Health and Medicine; Hydrocarbons; Nitro Compounds; Nitrobenzenes; Ophthalmic Antiinfectives; Ophthalmic Preparations; Pharmaceuticals; Propylene Glycols; Streptomycin Therapy; Topical Agents; Triazenes EN Campo Grande Brazil South America Antibiotics Antiinfectives Bacterial Infections and Mycoses Benzamidines Chloramphenicol Chloramphenicol Therapy Diminazene Drugs and Therapies Health and Medicine Hydrocarbons Nitro Compounds Nitrobenzenes Ophthalmic Antiinfectives Ophthalmic Preparations Pharmaceuticals Propylene Glycols Streptomycin Therapy Topical Agents Triazenes 2376 2376 1 03/24/23 20230217 NES 230217 2023 FEB 17 (NewsRx) -- By a News Reporter-Staff News Editor at Drug Week -- Current study results on Bacterial Infections and Mycoses have been published. Campo Grande, Brazil, South America, Antibiotics, Antiinfectives, Bacterial Infections and Mycoses, Benzamidines, Chloramphenicol, Chloramphenicol Therapy, Diminazene, Drugs and Therapies, Health and Medicine, Hydrocarbons, Nitrobenzenes, Ophthalmic Antiinfectives, Ophthalmic Preparations, Pharmaceuticals, Propylene Glycols, Streptomycin Therapy, Topical Agents, Triazenes, Nitro Compounds. [Extracted from the article]