187 results on '"Strauß, Hans Georg"'
Search Results
2. Mammakarzinomrezidiv und metastasiertes Mammakarzinom
- Author
-
Kantelhardt, Eva J., Vetter, Martina, Strauß, Hans-Georg, Wacker, Jürgen, editor, Sillem, Martin, editor, Bastert, Gunther, editor, and Beckmann, Matthias W., editor
- Published
- 2020
- Full Text
- View/download PDF
3. Role of Pelvic Lymph Node Resection in Vulvar Squamous Cell Cancer: A Subset Analysis of the AGO-CaRE-1 Study
- Author
-
Woelber, Linn, Bommert, Mareike, Harter, Philipp, Prieske, Katharina, zu Eulenburg, Christine, Jueckstock, Julia, Hilpert, Felix, de Gregorio, Nikolaus, Iborra, Severine, Sehouli, Jalid, Ignatov, Atanas, Hillemanns, Peter, Fuerst, Sophie, Strauss, Hans-Georg, Baumann, Klaus, Beckmann, Matthias, Mustea, Alexander, Meier, Werner, Mahner, Sven, and Jaeger, Anna
- Published
- 2021
- Full Text
- View/download PDF
4. Age, treatment and prognosis of patients with squamous cell vulvar cancer (VSCC) - analysis of the AGO-CaRE-1 study
- Author
-
Prieske, Katharina, Woelber, Linn, Muallem, Mustafa Zelal, Eulenburg, Christine, Jueckstock, Julia Kathrin, Hilpert, Felix, de Gregorio, Nikolaus, Iborra, Severine, Ignatov, Atanas, Hillemanns, Peter, Fuerst, Sophie, Strauss, Hans-Georg, Baumann, Klaus, Beckmann, Matthias, Mustea, Alexander, Meier, Werner, Harter, Philipp, Wimberger, Pauline, Sehouli, Jalid, and Mahner, Sven
- Published
- 2021
- Full Text
- View/download PDF
5. Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
- Author
-
Dominguez-Valentin, Mev, Crosbie, Emma J., Engel, Christoph, Aretz, Stefan, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Nakken, Sigve, Hovig, Eivind, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria Grazia, Cavestro, Giulia Martina, Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Strauß, Hans-Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka-Pekka, Plazzer, John-Paul, Pineda, Marta, Navarro, Matilde, Vidal, Joan Brunet, Kariv, Revital, Rosner, Guy, Piñero, Tamara Alejandra, Gonzalez, María Laura, Kalfayan, Pablo, Ryan, Neil, ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Burn, John, Greenblatt, Marc, de Vos tot Nederveen Cappel, Wouter H., Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Büttner, Reinhard, Görgens, Heike, Morak, Monika, Holzapfel, Stefanie, Hüneburg, Robert, von Knebel Doeberitz, Magnus, Loeffler, Markus, Rahner, Nils, Weitz, Jürgen, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Lepistö, Anna, Auranen, Annika, Hopper, John L., Win, Aung Ko, Haile, Robert W., Lindor, Noralane M., Gallinger, Steven, Le Marchand, Loïc, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Okkels, Henrik, Ketabi, Zohreh, Denton, Oliver G., Rødland, Einar Andreas, Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Möslein, Gabriela, Sampson, Julian R., Evans, D. Gareth, Seppälä, Toni T., and Møller, Pål
- Published
- 2021
- Full Text
- View/download PDF
6. Validation and functional follow‐up of cervical cancer risk variants at the HLA locus.
- Author
-
Eisenblätter, Rieke, Seifert, Finja, Schürmann, Peter, Beckhaus, Theresa, Hanel, Patricia, Jentschke, Matthias, Böhmer, Gerd, Strauß, Hans‐Georg, Hirchenhain, Christine, Schmidmayr, Monika, Müller, Florian, Hein, Alexander, Stuebs, Frederik, Koch, Martin, Ruebner, Matthias, Beckmann, Matthias W., Fasching, Peter A., Luyten, Alexander, Häfner, Norman, and Hillemanns, Peter
- Subjects
CERVICAL cancer ,EPITHELIUM ,CANCER susceptibility ,DISEASE risk factors ,CANCER invasiveness ,DYSPLASIA - Abstract
Cervical cancer is the fourth most common cancer in females. Genome‐wide association studies (GWASs) have proposed cervical cancer susceptibility variants at the HLA locus on chromosome 6p21. To corroborate these findings and investigate their functional impact in cervical tissues and cell lines, we genotyped nine variants from cervical cancer GWASs (rs17190106, rs535777, rs1056429, rs2763979, rs143954678, rs113937848, rs3117027, rs3130214, and rs9477610) in a German hospital‐based series of 1122 invasive cervical cancers, 1408 dysplasias, and 1196 healthy controls. rs17190106, rs1056429 and rs143954678/rs113937848 associated with cervical malignancies overall, while rs17190106 and rs535777 associated specifically with invasive cancer (OR = 0.69, 95% CI = 0.55–0.86, p = 0.001) or adenocarcinomas (OR = 1.63, 95%CI = 1.17–2.27, p = 0.004), respectively. We tested these and one previously genotyped GWAS variant, rs9272117, for potential eQTL effects on 36 gene transcripts at the HLA locus in 280 cervical epithelial tissues. The strongest eQTL pairs were rs9272117 and HLA‐DRB6 (p = 1.9x10E‐5), rs1056429 and HLA‐DRB5 (p = 2.5x10E‐4), and rs535777 and HLA‐DRB1 (p = 2.7x10E‐4). We also identified transcripts that were specifically upregulated (DDX39B, HCP5, HLA‐B, LTB, NFKBIL1) or downregulated (HLA‐C, HLA‐DPB2) in HPV+ or HPV16+ samples. In comparison, treating cervical epithelial cells with proinflammatory cytokine γ‐IFN led to a dose‐dependent induction of HCP5, HLA‐B, HLA‐C, HLA‐DQB1, HLA‐DRB1, HLA‐DRB6, and repression of HSPA1L. Taken together, these results identify relevant genes from both the MHC class I and II regions that are inflammation‐responsive in cervical epithelium and associate with HPV (HCP5, HLA‐B, HLA‐C) and/or with genomic cervical cancer risk variants (HLA‐DRB1, HLA‐DRB6). They may thus constitute important contributors to the immune escape of precancerous cells after HPV‐infection. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
7. Bevacizumab and platinum-based combinations for recurrent ovarian cancer: a randomised, open-label, phase 3 trial
- Author
-
Ackermann, Sven, Anthuber, Christoph, Aydogdu, Mustafa, Baldauf, Angelika, Bauer, Wolfgang, Behringer, Dirk, Belau, Antje, Bender, Alexandra, Brucker, Cosima, Burges, Alexander, Canzler, Ulrich, Daabach, Trygve, Denschlag, Dominik, Deryal, Mustafa, Dörfel, Steffen, Ebert, Juliane, El-Balat, Ahmed, Fehm, Tanja, Feidicker, Susanne Maria, Feisel-Schwickardi, Gabriele, Felberbaum, Ricardo, Frank, Matthias, Gebauer, Gerhard, Gerber, Bernd, Gerhardt, Axel, Grafe, Andrea, Griesshammer, Martin, Grischke, Eva-Maria, Gröll, Isolde, Gropp-Meier, Martina, Hager, Dietrich, Hanf, Volker, Hannig, Carla Verena, Hantschmann, Peer, Harter, Philipp, Hauzenberger, Tanja, Herwig, Uwe, Heubner, Martin, Hielscher, Carsten, Hilpert, Felix, Hitschold, Thomas, Hofmann, Manfred, Jackisch, Christian, Janni, Wolfgang, Kiesel, Ludwig, Ko, Yon-Dschun, Koch, Hans-Joachim, Krabisch, Petra, Krieger, Peter, Kubin, Thomas, Kühn, Thorsten, Lampe, Björn, Ledwon, Peter, Lemster, Sabine, Lex, Benno, Liebrich, Clemens, Lorenz, Ralf, Lück, Hans-Joachim, Mahner, Sven, Mallmann, Peter, Marmé, Frederik, Meier, Werner, Meinerz, Wolfgang, Menke, Götz, Möbus, Volker, Müller, Thomas, Müller, Volker, Neunhöffer, Tanja, Ober, Angelika, Oskay-Özcelik, Gülten, Ostertag, Horst, Park-Simon, Tjoung-Won, Pölcher, Martin, Rautenberg, Beate, Rein, Daniel, Reiter, Wilhelm, Rempen, Andreas, Runnebaum, Ingo, Schmalfeldt, Barbara, Schmidt, Marcus, Schnohr, Sabine, Scholz, Heinz, Schröder, Willibald, Sehouli, Jalid, Simon, Eike, Sperfeld, Antje, Steckkönig, Annette, Strauß, Hans-Georg, Stuth, Ronaldo, Terhaag, Jürgen, Thiel, Falk, Thill, Marc, Tomé, Oliver, Uleer, Christoph, Vogel, Susanne, Voß, Hermann, Weigel, Michael, Winkler, Ulrich, Wischnik, Arthur, Zeiser, Tobias, Zorr, Andreas, Glasspool, Ros, Hudson, Emma, Jones, Rachel, Lafleur, Judith, Marth, Christian, Petru, Edgar, Reinthaller, Alexander, Antill, Yoland, Azer, Mary, Baron-Hay, Sally, Beale, Philip, Begbie, Stephen, Black, Allison, Briscoe, Karen, Dean, Andrew, Goh, Jeffrey, Harvey, Sandra, Lee, Chee, Matos, Marco, Meniawy, Tarek, Olesen, Inger, Shannon, Catherine, Vasey, Paul, Abadie-Lacourtoisie, Sophie, Arsene, Olivier, Barthier, Sophie, Becuwe-Roemer, Célia, Berton-Rigaud, Dominique, Cappiello-Bataller, Maria, Catala, Stéphanie, Costan, Cristina, Del Piano, Francesco, Deplanque, Gaël, Despax, Raymond, Dohollou, Nadine, Garnier-Tixidré, Claire, Grenier, Julien, Guardiola, Emmanuel, Hardy-Bessard, Anne-Claire, Joly, Florence, Kurtz, Jean-Emmanuel, Lefeuvre-Plesse, Claudia, Leheurteur, Marianne, Lesoin, Anne, Levache, Charles-Briac, L'Haridon, Tifenn, Longo, Raffaele, Lortholary, Alain, Meunier, Jérôme, Mouret-Reynier, Marie-Ange, Petit, Thierry, Raban, Nadia, Romano, Olivier, Vannetzel, Jean-Michel, Zannetti, Alain, Pfisterer, Jacobus, Shannon, Catherine M, Baumann, Klaus, Rau, Joern, Dean, Andrew P, Hein, Alexander, Zeimet, Alain G, Hanker, Lars C, Glasspool, Rosalind, de Gregorio, Nikolaus, Meniawy, Tarek M, Goh, Jeffrey C, Baron Hay, Sally, Kommoss, Stefan, and du Bois, Andreas
- Published
- 2020
- Full Text
- View/download PDF
8. Predicting the course of disease in recurrent vulvar cancer – A subset analysis of the AGO-CaRE-1 study
- Author
-
Woelber, Linn, Eulenburg, Christine, Kosse, Jens, Neuser, Petra, Heiss, Christoph, Hantschmann, Peer, Mallmann, Peter, Tanner, Berno, Pfisterer, Jacobus, Jückstock, Julia, Hilpert, Felix, de Gregorio, Nikolaus, Iborra, Severine, Sehouli, Jalid, Ignatov, Atanas, Hillemanns, Peter, Fürst, Sophie, Strauss, Hans-Georg, Mahner, Sven, and Prieske, Katharina
- Published
- 2019
- Full Text
- View/download PDF
9. Lymph node ratio in inguinal lymphadenectomy for squamous cell vulvar cancer: Results from the AGO-CaRE-1 study
- Author
-
Polterauer, Stephan, Schwameis, Richard, Grimm, Christoph, Hillemanns, Peter, Jückstock, Julia, Hilpert, Felix, de Gregorio, Nikolaus, Hasenburg, Annette, Sehouli, Jalid, Fürst, Sophie Theresa, Strauß, Hans Georg, Baumann, Klaus, Thiel, Falk, Mustea, Alexander, Harter, Philipp, Wimberger, Pauline, Kölbl, Heinz, Reinthaller, Alexander, Woelber, Linn, and Mahner, Sven
- Published
- 2019
- Full Text
- View/download PDF
10. Supplementary Figure S1 from Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer
- Author
-
Leman, Raphaël, primary, Muller, Etienne, primary, Legros, Angelina, primary, Goardon, Nicolas, primary, Chentli, Imène, primary, Atkinson, Alexandre, primary, Tranchant, Aurore, primary, Castera, Laurent, primary, Krieger, Sophie, primary, Ricou, Agathe, primary, Boulouard, Flavie, primary, Joly, Florence, primary, Boucly, Romain, primary, Dumont, Aurélie, primary, Basset, Noémie, primary, Coulet, Florence, primary, Chevalier, Louise-Marie, primary, Rouleau, Etienne, primary, Leitner, Katharina, primary, González-Martin, Antonio, primary, Gargiulo, Piera, primary, Lück, Hans-Joachim, primary, Genestie, Catherine, primary, Bogner, Gerhard, primary, Marth, Christian, primary, Petru, Edgar, primary, Reinthaller, Alexander, primary, Schauer, Christian, primary, Sevelda, Paul, primary, D'Hondt, Lionel, primary, Vergote, Ignace, primary, Vuylsteke, Peter, primary, Hietanen, Sakari, primary, Lindahl, Gabriel, primary, Mäenpää, Johanna, primary, Nøttrup, Trine Jakobi, primary, Puistola, Ulla, primary, Abadie-Lacourtoisie, Sophie, primary, Alexandre, Jérôme, primary, Boissier, Emilie, primary, Bourgeois, Hugues, primary, Chevalier-Place, Annick, primary, Combe, Pierre, primary, Costan, Cristina, primary, Dauba, Jérôme, primary, De Cock, Laure, primary, Desauw, Christophe, primary, Despax, Raymond, primary, Dohollou, Nadine, primary, Dubot, Coraline, primary, Fabbro, Michel, primary, Favier, Laure, primary, Floquet, Anne, primary, Follana, Philippe, primary, Tixidre, Claire Garnier, primary, Garnier, Georges, primary, Gladieff, Laurence, primary, Grenier, Julien, primary, Guillemet, Cécile, primary, Hardy-Bessard, Anne-Claire, primary, Kalbacher, Elsa, primary, Kaminsky, Marie-Christine, primary, Kurtz, Jean-Emmanuel, primary, Largillier, Rémy, primary, Lefeuvre-Plesse, Claudia, primary, Lesoin, Anne, primary, Levache, Charles-Briac, primary, L'Haridon, Tifenn, primary, Lortholary, Alain, primary, Lotz, Jean-Pierre, primary, Meunier, Jérôme, primary, Mousseau, Mirerille, primary, Mouret-Reynier, Marie-Ange, primary, Pautier, Patricia, primary, Petit, Thierry, primary, Provansal, Magali, primary, Pujade-Lauraine, Eric, primary, Raban, Nadia, primary, Ray-Coquard, Isabelle, primary, Rodrigues, Manuel, primary, Selle, Frédéric, primary, Sverdlin, Robert, primary, Tazi, Youssef, primary, You, Benoît, primary, Aktas, Bahriye, primary, Bauerschlag, Dirk Olaf, primary, Beck, Thomas, primary, Belau, Antje, primary, Bronger, Holger, primary, Buchholz, Stefan, primary, Buderath, Paul, primary, Burges, Alexander, primary, Canzler, Ulrich, primary, de Gregorio, Nikolaus, primary, Denschlag, Dominik, primary, Dieterich, Max, primary, Eichbaum, Michael, primary, El-Balat, Ahmed, primary, Emons, Günter, primary, Fasching, Peter, primary, Feisel-Schwickardi, Gabriele, primary, Frank, Matthias, primary, Friedrich, Michael, primary, Grischke, Eva-Maria, primary, Gropp-Meier, Martina, primary, Hanker, Lars, primary, Hannig, Carla, primary, Harter, Philipp, primary, Hasenburg, Annette, primary, Hellriegel, Martin, primary, Herwig, Uwe, primary, Heubner, Martin, primary, Hulde, Joachim, primary, Jackisch, Christian, primary, Kögel, Matthias, primary, Krieger, Peter, primary, Kühn, Thorsten, primary, Liebrich, Clemens, primary, Mallmann, Peter, primary, Marmé, Frederik, primary, Meier, Werner, primary, Möbus, Voker, primary, Mohamed, Omar Farag, primary, Nestle-Krämling, Carolin, primary, Neunhöffer, Tanja, primary, Oskay-Özcelik, Gülten, primary, Park-Simon, Tjoung-Won, primary, Rautenberg, Beate, primary, Rein, Daniel, primary, Ruhwedel, Wencke, primary, Runnebaum, Ingo, primary, Sagasser, Jacqueline, primary, Schmalfeldt, Barbara, primary, Schneeweiss, Andreas, primary, Schnelzer, Andreas, primary, Scholz, Heinz, primary, Sehouli, Jalid, primary, Sperfeld, Antje, primary, Steckkönig, Annette, primary, Strauß, Hans-Georg, primary, Tomé, Oliver, primary, Treustedt, Jörn, primary, Voß, Hermann, primary, Wischnik, Arthur, primary, Witteler, Ralf, primary, Wöckel, Achim, primary, Woeltjen, Hans-Heinrich, primary, Zorr, Andreas, primary, Bologna, Alessandra, primary, Colombo, Nicoletta, primary, Tognon, Germana, primary, Cinieri, Saverio, primary, Lorusso, Domenica, primary, Mosconi, Anna Maria, primary, Pignata, Sandro, primary, Savarese, Antonella, primary, Scambia, Giovanni, primary, Sorio, Roberto, primary, Zamagni, Claudio, primary, Fujiwara, Keiichi, primary, Fujiwara, Hiroyuki, primary, Kobayashi, Hiroaki, primary, Matsumoto, Takashi, primary, Nagao, Shoji, primary, Satoh, Toyomi, primary, Yonemori, Kan, primary, Yoshida, Hiroyuki, primary, Bratos, Raquel, primary, Caballero, Cristina, primary, Garica, Yolanda, primary, González-Martín, Antonio, primary, Alia, Eva Maria Guerra, primary, Hernando, Susana, primary, Herrero, Ana, primary, Lainez, Nuria, primary, Manso, Luis, primary, Martin, Cristina, primary, Murata, Eleonor, primary, Ortega, Eugenia, primary, Palacio, Isabel, primary, Poveda, Andres, primary, Romero, Ignacio, primary, Rubio, Maria Jesús, primary, and Vaur, Dominique, primary
- Published
- 2023
- Full Text
- View/download PDF
11. Supplementary Table S2 from Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer
- Author
-
Leman, Raphaël, primary, Muller, Etienne, primary, Legros, Angelina, primary, Goardon, Nicolas, primary, Chentli, Imène, primary, Atkinson, Alexandre, primary, Tranchant, Aurore, primary, Castera, Laurent, primary, Krieger, Sophie, primary, Ricou, Agathe, primary, Boulouard, Flavie, primary, Joly, Florence, primary, Boucly, Romain, primary, Dumont, Aurélie, primary, Basset, Noémie, primary, Coulet, Florence, primary, Chevalier, Louise-Marie, primary, Rouleau, Etienne, primary, Leitner, Katharina, primary, González-Martin, Antonio, primary, Gargiulo, Piera, primary, Lück, Hans-Joachim, primary, Genestie, Catherine, primary, Bogner, Gerhard, primary, Marth, Christian, primary, Petru, Edgar, primary, Reinthaller, Alexander, primary, Schauer, Christian, primary, Sevelda, Paul, primary, D'Hondt, Lionel, primary, Vergote, Ignace, primary, Vuylsteke, Peter, primary, Hietanen, Sakari, primary, Lindahl, Gabriel, primary, Mäenpää, Johanna, primary, Nøttrup, Trine Jakobi, primary, Puistola, Ulla, primary, Abadie-Lacourtoisie, Sophie, primary, Alexandre, Jérôme, primary, Boissier, Emilie, primary, Bourgeois, Hugues, primary, Chevalier-Place, Annick, primary, Combe, Pierre, primary, Costan, Cristina, primary, Dauba, Jérôme, primary, De Cock, Laure, primary, Desauw, Christophe, primary, Despax, Raymond, primary, Dohollou, Nadine, primary, Dubot, Coraline, primary, Fabbro, Michel, primary, Favier, Laure, primary, Floquet, Anne, primary, Follana, Philippe, primary, Tixidre, Claire Garnier, primary, Garnier, Georges, primary, Gladieff, Laurence, primary, Grenier, Julien, primary, Guillemet, Cécile, primary, Hardy-Bessard, Anne-Claire, primary, Kalbacher, Elsa, primary, Kaminsky, Marie-Christine, primary, Kurtz, Jean-Emmanuel, primary, Largillier, Rémy, primary, Lefeuvre-Plesse, Claudia, primary, Lesoin, Anne, primary, Levache, Charles-Briac, primary, L'Haridon, Tifenn, primary, Lortholary, Alain, primary, Lotz, Jean-Pierre, primary, Meunier, Jérôme, primary, Mousseau, Mirerille, primary, Mouret-Reynier, Marie-Ange, primary, Pautier, Patricia, primary, Petit, Thierry, primary, Provansal, Magali, primary, Pujade-Lauraine, Eric, primary, Raban, Nadia, primary, Ray-Coquard, Isabelle, primary, Rodrigues, Manuel, primary, Selle, Frédéric, primary, Sverdlin, Robert, primary, Tazi, Youssef, primary, You, Benoît, primary, Aktas, Bahriye, primary, Bauerschlag, Dirk Olaf, primary, Beck, Thomas, primary, Belau, Antje, primary, Bronger, Holger, primary, Buchholz, Stefan, primary, Buderath, Paul, primary, Burges, Alexander, primary, Canzler, Ulrich, primary, de Gregorio, Nikolaus, primary, Denschlag, Dominik, primary, Dieterich, Max, primary, Eichbaum, Michael, primary, El-Balat, Ahmed, primary, Emons, Günter, primary, Fasching, Peter, primary, Feisel-Schwickardi, Gabriele, primary, Frank, Matthias, primary, Friedrich, Michael, primary, Grischke, Eva-Maria, primary, Gropp-Meier, Martina, primary, Hanker, Lars, primary, Hannig, Carla, primary, Harter, Philipp, primary, Hasenburg, Annette, primary, Hellriegel, Martin, primary, Herwig, Uwe, primary, Heubner, Martin, primary, Hulde, Joachim, primary, Jackisch, Christian, primary, Kögel, Matthias, primary, Krieger, Peter, primary, Kühn, Thorsten, primary, Liebrich, Clemens, primary, Mallmann, Peter, primary, Marmé, Frederik, primary, Meier, Werner, primary, Möbus, Voker, primary, Mohamed, Omar Farag, primary, Nestle-Krämling, Carolin, primary, Neunhöffer, Tanja, primary, Oskay-Özcelik, Gülten, primary, Park-Simon, Tjoung-Won, primary, Rautenberg, Beate, primary, Rein, Daniel, primary, Ruhwedel, Wencke, primary, Runnebaum, Ingo, primary, Sagasser, Jacqueline, primary, Schmalfeldt, Barbara, primary, Schneeweiss, Andreas, primary, Schnelzer, Andreas, primary, Scholz, Heinz, primary, Sehouli, Jalid, primary, Sperfeld, Antje, primary, Steckkönig, Annette, primary, Strauß, Hans-Georg, primary, Tomé, Oliver, primary, Treustedt, Jörn, primary, Voß, Hermann, primary, Wischnik, Arthur, primary, Witteler, Ralf, primary, Wöckel, Achim, primary, Woeltjen, Hans-Heinrich, primary, Zorr, Andreas, primary, Bologna, Alessandra, primary, Colombo, Nicoletta, primary, Tognon, Germana, primary, Cinieri, Saverio, primary, Lorusso, Domenica, primary, Mosconi, Anna Maria, primary, Pignata, Sandro, primary, Savarese, Antonella, primary, Scambia, Giovanni, primary, Sorio, Roberto, primary, Zamagni, Claudio, primary, Fujiwara, Keiichi, primary, Fujiwara, Hiroyuki, primary, Kobayashi, Hiroaki, primary, Matsumoto, Takashi, primary, Nagao, Shoji, primary, Satoh, Toyomi, primary, Yonemori, Kan, primary, Yoshida, Hiroyuki, primary, Bratos, Raquel, primary, Caballero, Cristina, primary, Garica, Yolanda, primary, González-Martín, Antonio, primary, Alia, Eva Maria Guerra, primary, Hernando, Susana, primary, Herrero, Ana, primary, Lainez, Nuria, primary, Manso, Luis, primary, Martin, Cristina, primary, Murata, Eleonor, primary, Ortega, Eugenia, primary, Palacio, Isabel, primary, Poveda, Andres, primary, Romero, Ignacio, primary, Rubio, Maria Jesús, primary, and Vaur, Dominique, primary
- Published
- 2023
- Full Text
- View/download PDF
12. Data from Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer
- Author
-
Leman, Raphaël, primary, Muller, Etienne, primary, Legros, Angelina, primary, Goardon, Nicolas, primary, Chentli, Imène, primary, Atkinson, Alexandre, primary, Tranchant, Aurore, primary, Castera, Laurent, primary, Krieger, Sophie, primary, Ricou, Agathe, primary, Boulouard, Flavie, primary, Joly, Florence, primary, Boucly, Romain, primary, Dumont, Aurélie, primary, Basset, Noémie, primary, Coulet, Florence, primary, Chevalier, Louise-Marie, primary, Rouleau, Etienne, primary, Leitner, Katharina, primary, González-Martin, Antonio, primary, Gargiulo, Piera, primary, Lück, Hans-Joachim, primary, Genestie, Catherine, primary, Bogner, Gerhard, primary, Marth, Christian, primary, Petru, Edgar, primary, Reinthaller, Alexander, primary, Schauer, Christian, primary, Sevelda, Paul, primary, D'Hondt, Lionel, primary, Vergote, Ignace, primary, Vuylsteke, Peter, primary, Hietanen, Sakari, primary, Lindahl, Gabriel, primary, Mäenpää, Johanna, primary, Nøttrup, Trine Jakobi, primary, Puistola, Ulla, primary, Abadie-Lacourtoisie, Sophie, primary, Alexandre, Jérôme, primary, Boissier, Emilie, primary, Bourgeois, Hugues, primary, Chevalier-Place, Annick, primary, Combe, Pierre, primary, Costan, Cristina, primary, Dauba, Jérôme, primary, De Cock, Laure, primary, Desauw, Christophe, primary, Despax, Raymond, primary, Dohollou, Nadine, primary, Dubot, Coraline, primary, Fabbro, Michel, primary, Favier, Laure, primary, Floquet, Anne, primary, Follana, Philippe, primary, Tixidre, Claire Garnier, primary, Garnier, Georges, primary, Gladieff, Laurence, primary, Grenier, Julien, primary, Guillemet, Cécile, primary, Hardy-Bessard, Anne-Claire, primary, Kalbacher, Elsa, primary, Kaminsky, Marie-Christine, primary, Kurtz, Jean-Emmanuel, primary, Largillier, Rémy, primary, Lefeuvre-Plesse, Claudia, primary, Lesoin, Anne, primary, Levache, Charles-Briac, primary, L'Haridon, Tifenn, primary, Lortholary, Alain, primary, Lotz, Jean-Pierre, primary, Meunier, Jérôme, primary, Mousseau, Mirerille, primary, Mouret-Reynier, Marie-Ange, primary, Pautier, Patricia, primary, Petit, Thierry, primary, Provansal, Magali, primary, Pujade-Lauraine, Eric, primary, Raban, Nadia, primary, Ray-Coquard, Isabelle, primary, Rodrigues, Manuel, primary, Selle, Frédéric, primary, Sverdlin, Robert, primary, Tazi, Youssef, primary, You, Benoît, primary, Aktas, Bahriye, primary, Bauerschlag, Dirk Olaf, primary, Beck, Thomas, primary, Belau, Antje, primary, Bronger, Holger, primary, Buchholz, Stefan, primary, Buderath, Paul, primary, Burges, Alexander, primary, Canzler, Ulrich, primary, de Gregorio, Nikolaus, primary, Denschlag, Dominik, primary, Dieterich, Max, primary, Eichbaum, Michael, primary, El-Balat, Ahmed, primary, Emons, Günter, primary, Fasching, Peter, primary, Feisel-Schwickardi, Gabriele, primary, Frank, Matthias, primary, Friedrich, Michael, primary, Grischke, Eva-Maria, primary, Gropp-Meier, Martina, primary, Hanker, Lars, primary, Hannig, Carla, primary, Harter, Philipp, primary, Hasenburg, Annette, primary, Hellriegel, Martin, primary, Herwig, Uwe, primary, Heubner, Martin, primary, Hulde, Joachim, primary, Jackisch, Christian, primary, Kögel, Matthias, primary, Krieger, Peter, primary, Kühn, Thorsten, primary, Liebrich, Clemens, primary, Mallmann, Peter, primary, Marmé, Frederik, primary, Meier, Werner, primary, Möbus, Voker, primary, Mohamed, Omar Farag, primary, Nestle-Krämling, Carolin, primary, Neunhöffer, Tanja, primary, Oskay-Özcelik, Gülten, primary, Park-Simon, Tjoung-Won, primary, Rautenberg, Beate, primary, Rein, Daniel, primary, Ruhwedel, Wencke, primary, Runnebaum, Ingo, primary, Sagasser, Jacqueline, primary, Schmalfeldt, Barbara, primary, Schneeweiss, Andreas, primary, Schnelzer, Andreas, primary, Scholz, Heinz, primary, Sehouli, Jalid, primary, Sperfeld, Antje, primary, Steckkönig, Annette, primary, Strauß, Hans-Georg, primary, Tomé, Oliver, primary, Treustedt, Jörn, primary, Voß, Hermann, primary, Wischnik, Arthur, primary, Witteler, Ralf, primary, Wöckel, Achim, primary, Woeltjen, Hans-Heinrich, primary, Zorr, Andreas, primary, Bologna, Alessandra, primary, Colombo, Nicoletta, primary, Tognon, Germana, primary, Cinieri, Saverio, primary, Lorusso, Domenica, primary, Mosconi, Anna Maria, primary, Pignata, Sandro, primary, Savarese, Antonella, primary, Scambia, Giovanni, primary, Sorio, Roberto, primary, Zamagni, Claudio, primary, Fujiwara, Keiichi, primary, Fujiwara, Hiroyuki, primary, Kobayashi, Hiroaki, primary, Matsumoto, Takashi, primary, Nagao, Shoji, primary, Satoh, Toyomi, primary, Yonemori, Kan, primary, Yoshida, Hiroyuki, primary, Bratos, Raquel, primary, Caballero, Cristina, primary, Garica, Yolanda, primary, González-Martín, Antonio, primary, Alia, Eva Maria Guerra, primary, Hernando, Susana, primary, Herrero, Ana, primary, Lainez, Nuria, primary, Manso, Luis, primary, Martin, Cristina, primary, Murata, Eleonor, primary, Ortega, Eugenia, primary, Palacio, Isabel, primary, Poveda, Andres, primary, Romero, Ignacio, primary, Rubio, Maria Jesús, primary, and Vaur, Dominique, primary
- Published
- 2023
- Full Text
- View/download PDF
13. Supplementary Appendix S1 from Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer
- Author
-
Leman, Raphaël, primary, Muller, Etienne, primary, Legros, Angelina, primary, Goardon, Nicolas, primary, Chentli, Imène, primary, Atkinson, Alexandre, primary, Tranchant, Aurore, primary, Castera, Laurent, primary, Krieger, Sophie, primary, Ricou, Agathe, primary, Boulouard, Flavie, primary, Joly, Florence, primary, Boucly, Romain, primary, Dumont, Aurélie, primary, Basset, Noémie, primary, Coulet, Florence, primary, Chevalier, Louise-Marie, primary, Rouleau, Etienne, primary, Leitner, Katharina, primary, González-Martin, Antonio, primary, Gargiulo, Piera, primary, Lück, Hans-Joachim, primary, Genestie, Catherine, primary, Bogner, Gerhard, primary, Marth, Christian, primary, Petru, Edgar, primary, Reinthaller, Alexander, primary, Schauer, Christian, primary, Sevelda, Paul, primary, D'Hondt, Lionel, primary, Vergote, Ignace, primary, Vuylsteke, Peter, primary, Hietanen, Sakari, primary, Lindahl, Gabriel, primary, Mäenpää, Johanna, primary, Nøttrup, Trine Jakobi, primary, Puistola, Ulla, primary, Abadie-Lacourtoisie, Sophie, primary, Alexandre, Jérôme, primary, Boissier, Emilie, primary, Bourgeois, Hugues, primary, Chevalier-Place, Annick, primary, Combe, Pierre, primary, Costan, Cristina, primary, Dauba, Jérôme, primary, De Cock, Laure, primary, Desauw, Christophe, primary, Despax, Raymond, primary, Dohollou, Nadine, primary, Dubot, Coraline, primary, Fabbro, Michel, primary, Favier, Laure, primary, Floquet, Anne, primary, Follana, Philippe, primary, Tixidre, Claire Garnier, primary, Garnier, Georges, primary, Gladieff, Laurence, primary, Grenier, Julien, primary, Guillemet, Cécile, primary, Hardy-Bessard, Anne-Claire, primary, Kalbacher, Elsa, primary, Kaminsky, Marie-Christine, primary, Kurtz, Jean-Emmanuel, primary, Largillier, Rémy, primary, Lefeuvre-Plesse, Claudia, primary, Lesoin, Anne, primary, Levache, Charles-Briac, primary, L'Haridon, Tifenn, primary, Lortholary, Alain, primary, Lotz, Jean-Pierre, primary, Meunier, Jérôme, primary, Mousseau, Mirerille, primary, Mouret-Reynier, Marie-Ange, primary, Pautier, Patricia, primary, Petit, Thierry, primary, Provansal, Magali, primary, Pujade-Lauraine, Eric, primary, Raban, Nadia, primary, Ray-Coquard, Isabelle, primary, Rodrigues, Manuel, primary, Selle, Frédéric, primary, Sverdlin, Robert, primary, Tazi, Youssef, primary, You, Benoît, primary, Aktas, Bahriye, primary, Bauerschlag, Dirk Olaf, primary, Beck, Thomas, primary, Belau, Antje, primary, Bronger, Holger, primary, Buchholz, Stefan, primary, Buderath, Paul, primary, Burges, Alexander, primary, Canzler, Ulrich, primary, de Gregorio, Nikolaus, primary, Denschlag, Dominik, primary, Dieterich, Max, primary, Eichbaum, Michael, primary, El-Balat, Ahmed, primary, Emons, Günter, primary, Fasching, Peter, primary, Feisel-Schwickardi, Gabriele, primary, Frank, Matthias, primary, Friedrich, Michael, primary, Grischke, Eva-Maria, primary, Gropp-Meier, Martina, primary, Hanker, Lars, primary, Hannig, Carla, primary, Harter, Philipp, primary, Hasenburg, Annette, primary, Hellriegel, Martin, primary, Herwig, Uwe, primary, Heubner, Martin, primary, Hulde, Joachim, primary, Jackisch, Christian, primary, Kögel, Matthias, primary, Krieger, Peter, primary, Kühn, Thorsten, primary, Liebrich, Clemens, primary, Mallmann, Peter, primary, Marmé, Frederik, primary, Meier, Werner, primary, Möbus, Voker, primary, Mohamed, Omar Farag, primary, Nestle-Krämling, Carolin, primary, Neunhöffer, Tanja, primary, Oskay-Özcelik, Gülten, primary, Park-Simon, Tjoung-Won, primary, Rautenberg, Beate, primary, Rein, Daniel, primary, Ruhwedel, Wencke, primary, Runnebaum, Ingo, primary, Sagasser, Jacqueline, primary, Schmalfeldt, Barbara, primary, Schneeweiss, Andreas, primary, Schnelzer, Andreas, primary, Scholz, Heinz, primary, Sehouli, Jalid, primary, Sperfeld, Antje, primary, Steckkönig, Annette, primary, Strauß, Hans-Georg, primary, Tomé, Oliver, primary, Treustedt, Jörn, primary, Voß, Hermann, primary, Wischnik, Arthur, primary, Witteler, Ralf, primary, Wöckel, Achim, primary, Woeltjen, Hans-Heinrich, primary, Zorr, Andreas, primary, Bologna, Alessandra, primary, Colombo, Nicoletta, primary, Tognon, Germana, primary, Cinieri, Saverio, primary, Lorusso, Domenica, primary, Mosconi, Anna Maria, primary, Pignata, Sandro, primary, Savarese, Antonella, primary, Scambia, Giovanni, primary, Sorio, Roberto, primary, Zamagni, Claudio, primary, Fujiwara, Keiichi, primary, Fujiwara, Hiroyuki, primary, Kobayashi, Hiroaki, primary, Matsumoto, Takashi, primary, Nagao, Shoji, primary, Satoh, Toyomi, primary, Yonemori, Kan, primary, Yoshida, Hiroyuki, primary, Bratos, Raquel, primary, Caballero, Cristina, primary, Garica, Yolanda, primary, González-Martín, Antonio, primary, Alia, Eva Maria Guerra, primary, Hernando, Susana, primary, Herrero, Ana, primary, Lainez, Nuria, primary, Manso, Luis, primary, Martin, Cristina, primary, Murata, Eleonor, primary, Ortega, Eugenia, primary, Palacio, Isabel, primary, Poveda, Andres, primary, Romero, Ignacio, primary, Rubio, Maria Jesús, primary, and Vaur, Dominique, primary
- Published
- 2023
- Full Text
- View/download PDF
14. Association of two genomic variants with HPV type-specific risk of cervical cancer
- Author
-
Seifert, Finja, primary, Eisenblätter, Rieke, additional, Beckmann, Julia, additional, Schürmann, Peter, additional, Hanel, Patricia, additional, Jentschke, Matthias, additional, Böhmer, Gerd, additional, Strauß, Hans-Georg, additional, Hirchenhain, Christine, additional, Schmidmayr, Monika, additional, Müller, Florian, additional, Fasching, Peter, additional, Luyten, Alexander, additional, Häfner, Norman, additional, Dürst, Matthias, additional, Runnebaum, Ingo, additional, Hillemanns, Peter, additional, Dörk, Thilo, additional, and Ramachandran, Dhanya, additional
- Published
- 2023
- Full Text
- View/download PDF
15. Role of tumour-free margin distance for loco-regional control in vulvar cancer—a subset analysis of the Arbeitsgemeinschaft Gynäkologische Onkologie CaRE-1 multicenter study
- Author
-
Woelber, Linn, Griebel, Lis-Femke, Eulenburg, Christine, Sehouli, Jalid, Jueckstock, Julia, Hilpert, Felix, de Gregorio, Nikolaus, Hasenburg, Annette, Ignatov, Atanas, Hillemanns, Peter, Fuerst, Sophie, Strauss, Hans-Georg, Baumann, Klaus H., Thiel, Falk C., Mustea, Alexander, Meier, Werner, Harter, Philipp, Wimberger, Pauline, Hanker, Lars Christian, Schmalfeldt, Barbara, Canzler, Ulrich, Fehm, Tanja, Luyten, Alexander, Hellriegel, Martin, Kosse, Jens, Heiss, Christoph, Hantschmann, Peer, Mallmann, Peter, Tanner, Berno, Pfisterer, Jacobus, Richter, Barbara, Neuser, Petra, and Mahner, Sven
- Published
- 2016
- Full Text
- View/download PDF
16. Association of two genomic variants with HPV subtype-specific risk of cervical cancer
- Author
-
Ramachandran, Dhanya, primary, Seifert, Finja, additional, Eisenblätter, Rieke, additional, Beckmann, Julia, additional, Schürmann, Peter, additional, Hanel, Patricia, additional, Jentschke, M., additional, Böhmer, Gerd, additional, Strauß, Hans-Georg, additional, Hirchenhain, Christine, additional, Schmidmayr, Monika, additional, Müller, Florian, additional, Fasching, Peter, additional, Luyten, Alexander, additional, Häfner, Norman, additional, Dürst, Matthias, additional, Runnebaum, Ingo, additional, Hillemanns, Peter, additional, and Dörk, Thilo, additional
- Published
- 2023
- Full Text
- View/download PDF
17. Abstract P1-11-11: HER2-directed therapy in early breast cancer – improvement over 20 years
- Author
-
Thomssen, Christoph, primary, Engel, Julia, additional, Reinhardt, Kristin, additional, Strauß, Hans-Georg, additional, Große, Regina, additional, Barrot, Susanne, additional, Bauer, Marcus, additional, van Uden, Lisa, additional, Kaufhold, Sandy, additional, Schüler, Kathleen, additional, Wieder, Vanessa, additional, Kantelhardt, Eva J., additional, and Vetter, Martina, additional
- Published
- 2023
- Full Text
- View/download PDF
18. Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, April 2021)
- Author
-
Denschlag, Dominik, additional, Ackermann, Sven, additional, Battista, Marco Johannes, additional, Cremer, Wolfgang, additional, Egerer, Gerlinde, additional, Fehr, Matthias, additional, Follmann, Markus, additional, Haase, Heidemarie, additional, Harter, Philipp, additional, Hettmer, Simone, additional, Horn, Lars-Christian, additional, Juhasz-Boess, Ingolf, additional, Kast, Karin, additional, Köhler, Günter, additional, Kröncke, Thomas, additional, Lindel, Katja, additional, Mallmann, Peter, additional, Meyer-Steinacker, Regine, additional, Mustea, Alexander, additional, Petru, Edgar, additional, Reichardt, Peter, additional, Schmidt, Dietmar, additional, Strauss, Hans-Georg, additional, Thiel, Falk, additional, Ulrich, Uwe Andreas, additional, Vogl, Thomas, additional, Vordermark, Dirk, additional, Wallwiener, Markus, additional, Gass, Paul, additional, and Beckmann, Matthias W., additional
- Published
- 2022
- Full Text
- View/download PDF
19. Outcome After Sentinel Lymph Node Dissection in Vulvar Cancer: A Subgroup Analysis of the AGO-CaRE-1 Study
- Author
-
Klapdor, Rüdiger, Hillemanns, Peter, Wölber, Linn, Jückstock, Julia, Hilpert, Felix, de Gregorio, Nikolaus, Iborra, Severine, Sehouli, Jalid, Habermann, Anika, Fürst, Sophie Teresa, Strauß, Hans Georg, Baumann, Klaus, Thiel, Falk, Mustea, Alexander, Meier, Werner, Harter, Philipp, Wimberger, Pauline, Hanker, Lars, Schmalfeldt, Barbara, Canzler, Ulrich, Fehm, Tanja, Luyten, Alexander, Hellriegel, Martin, Kosse, Jens, Heiss, Christoph, Hantschmann, Peer, Mallmann, Peter, Tanner, Berno, Pfisterer, Jacobus, Richter, Barbara, Jäger, Martin, and Mahner, Sven
- Published
- 2017
- Full Text
- View/download PDF
20. Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No. 015/074, April 2021)
- Author
-
Denschlag, Dominik, Ackermann, Sven, Battista, Marco Johannes, Cremer, Wolfgang, Egerer, Gerlinde, Fehr, Matthias, Follmann, Markus, Haase, Heidemarie, Harter, Philipp, Hettmer, Simone, Horn, Lars-Christian, Juhasz-Boess, Ingolf, Kast, Karin, Köhler, Günter, Kröncke, Thomas, Lindel, Katja, Mallmann, Peter, Meyer-Steinacker, Regine, Mustea, Alexander, Petru, Edgar, Reichardt, Peter, Schmidt, Dietmar, Strauss, Hans-Georg, Thiel, Falk, Ulrich, Uwe Andreas, Vogl, Thomas, Vordermark, Dirk, Wallwiener, Markus, Gass, Paul, and Beckmann, Matthias W.
- Subjects
Maternity and Midwifery ,Obstetrics and Gynecology - Abstract
Purpose This is an official guideline, published and coordinated by the Germany Society for Gynecology and Obstetrics (Deutsche Gesellschaft für Gynäkologie und Geburtshilfe, DGGG). Because of their rarity and heterogeneous histopathology, uterine sarcomas are challenging in terms of their clinical management and therefore require a multidisciplinary approach. To our knowledge, there are currently no binding evidence-based recommendations for the appropriate management of this heterogeneous group of tumors. Methods This S2k guideline was first published in 2015. The update published here is once again the result of the consensus of a representative interdisciplinary committee of experts who were commissioned by the Guidelines Committee of the DGGG to carry out a systematic search of the literature on uterine sarcomas. Members of the participating professional societies achieved a formal consensus after a structured consensus process. Recommendations 1.1 Epidemiology, classification, staging of uterine sarcomas. 1.2 Symptoms, general diagnostic workup, general pathology or genetic predisposition to uterine sarcomas. 2. Management of leiomyosarcomas. 3. Management of low-grade endometrial stromal sarcomas. 4. Management of high-grade endometrial stromal sarcoma and undifferentiated uterine sarcomas. 5. Management of adenosarcomas. 6. Rhabdomyosarcomas of the uterus in children and adolescents. 7. Follow-up of uterine sarcomas. 8. Management of morcellated uterine sarcomas. 9. Information provided to patients.
- Published
- 2022
21. 2022-RA-1725-ESGO Pazopanib with Topotecan weekly for patients with platinum-resistant or intermediate-sensitive recurrent ovarian cancer- results of a multicentre NOGGO phase I and II study (TOPAZ)
- Author
-
Arndt, Tjadina, primary, Chekerov, Radoslav, additional, Pietzner, Klaus, additional, Yalcinkaya, Isil, additional, Canzler, Ulrich, additional, Wimberger, Pauline, additional, Strauß, Hans Georg, additional, Mahner, Sven, additional, Woelber, Linn, additional, de Gregorio, Nikolaus, additional, Hacker, Ulrich Thorsten, additional, Abel, Ekkehard von, additional, Richter, Rolf, additional, and Sehouli, Jalid, additional
- Published
- 2022
- Full Text
- View/download PDF
22. Genome-wide association study and functional follow-up identify 14q12 as a candidate risk locus for cervical cancer
- Author
-
Ramachandran, Dhanya, Dennis, Joe, Fachal, Laura, Schürmann, Peter, Bousset, Kristine, Hülse, Fabienne, Mao, Qianqian, Wang, Yingying, Jentschke, Matthias, Böhmer, Gerd, Strauß, Hans-Georg, Hirchenhain, Christine, Schmidmayr, Monika, Müller, Florian, Runnebaum, Ingo, Hein, Alexander, Stübs, Frederik, Koch, Martin, Ruebner, Matthias, Beckmann, Matthias W, Fasching, Peter A, Luyten, Alexander, Dürst, Matthias, Hillemanns, Peter, Easton, Douglas F, Dörk, Thilo, Ramachandran, Dhanya [0000-0001-8139-7799], Dörk, Thilo [0000-0002-9458-0282], and Apollo - University of Cambridge Repository
- Subjects
Papillomavirus Infections ,Humans ,Uterine Cervical Neoplasms ,Female ,Forkhead Transcription Factors ,Genetic Predisposition to Disease ,Nerve Tissue Proteins ,Papillomaviridae ,Polymorphism, Single Nucleotide ,Follow-Up Studies ,Genome-Wide Association Study - Abstract
Cervical cancer is among the leading causes of cancer-related death in females worldwide. Infection by human papillomavirus (HPV) is an established risk factor for cancer development. However, genetic factors contributing to disease risk remain largely unknown. We report on a genome-wide association study (GWAS) on 375 German cervical cancer patients and 866 healthy controls, followed by a replication study comprising 658 patients with invasive cervical cancer, 1361 with cervical dysplasia and 841 healthy controls. Functional validation was performed for the top GWAS variant on chromosome 14q12 (rs225902, close to PRKD1). After bioinformatic annotation and in silico predictions, we performed transcript analysis in a cervical tissue series of 317 samples and demonstrate rs225902 as an expression quantitative trait locus (eQTL) for FOXG1 and two tightly co-regulated long non-coding RNAs at this genomic region, CTD-2251F13 (lnc-PRKD1-1) and CTD-2503I6 (lnc-FOXG1-6). We also show allele-specific effects of the 14q12 variants via luciferase assays. We propose a combined effect of genotype, HPV status and gene expression at this locus on cervical cancer progression. Taken together, this work uncovers a potential candidate locus with regulatory functions and contributes to the understanding of genetic susceptibility to cervical cancer.
- Published
- 2022
23. T-Cell Density at the Invasive Margin and Immune Phenotypes Predict Outcome in Vulvar Squamous Cell Cancer
- Author
-
Burandt, Eike, primary, Blessin, Niclas C., additional, Rolschewski, Ann-Christin, additional, Lutz, Florian, additional, Mandelkow, Tim, additional, Yang, Cheng, additional, Bady, Elena, additional, Reiswich, Viktor, additional, Simon, Ronald, additional, Sauter, Guido, additional, Mahner, Sven, additional, Gregorio, Nikolaus de, additional, Klapdor, Rüdiger, additional, Kalder, Matthias, additional, Braicu, Elena I., additional, Fürst, Sophie, additional, Klar, Maximilian, additional, Strauß, Hans-Georg, additional, Prieske, Katharina, additional, and Wölber, Linn, additional
- Published
- 2022
- Full Text
- View/download PDF
24. Immune phenotypes and T-cell density at the invasive margin correlate with prognosis in epithelial vulvar cancer.
- Author
-
Burandt, E C, primary, Blessin, Niclas, additional, Rolschewski, Ann-Christin, additional, Lutz, Florian, additional, Mandelkow, Tim, additional, Yang, Cheng, additional, Bady, Elena, additional, Reiswich, Viktor, additional, Simon, Ronald, additional, Sauter, Guido, additional, Mahner, Sven, additional, de Gregorio, Nikolaus, additional, Klapdor, Rüdiger, additional, Kalder, Matthias, additional, Braicu, Ioana, additional, Fuerst, Sophie, additional, Klar, Maximillian, additional, Strauss, Hans-Georg, additional, Prieske, Katharina, additional, and Woelber, Linn Lena, additional
- Published
- 2022
- Full Text
- View/download PDF
25. Epidemiological and demographic characteristics of gynecological sarcoma: Results of the prospective intergroup registry for gynecological sarcoma in Germany (REGSA–NOGGO RU1).
- Author
-
Roser, Eva, primary, Noack, Anne-Sophie, additional, Zocholl, Dario, additional, Kommoss, Stefan, additional, Harter, Philipp, additional, Kalder, Matthias, additional, Egger, Eva-Katherina, additional, Buderath, Paul, additional, Marth, Christian, additional, Ulrich, Uwe Andreas, additional, Klar, Maximillian, additional, Weigel, Michael, additional, Traub, Lea Franziska, additional, Strauss, Hans-Georg, additional, Hanker, Lars Ch., additional, Wimberger, Pauline, additional, Pölcher, Martin, additional, Beck, Felix, additional, Pietzner, Klaus, additional, and Sehouli, Jalid, additional
- Published
- 2022
- Full Text
- View/download PDF
26. Phase II study of fulvestrant 250 mg/month in patients with recurrent or metastatic endometrial cancer: A study of the Arbeitsgemeinschaft Gynäkologische Onkologie
- Author
-
Emons, Günter, Günthert, Andreas, Thiel, Falk C., Camara, Oumar, Strauss, Hans-Georg, Breitbach, Georg-Peter, Kölbl, Heinz, Reimer, Toralf, Finas, Dominique, and Rensing, Klaus
- Published
- 2013
- Full Text
- View/download PDF
27. Quality of life and sexual function in patients with borderline tumors of the ovary. A substudy of the Arbeitsgemeinschaft Gynaekologische Onkologie (AGO) study group ROBOT study
- Author
-
Farthmann, Juliane, Hasenburg, Annette, Weil, Meike, Fotopoulou, Christina, Ewald-Riegler, Nina, du Bois, Oya, Trillsch, Fabian, Mahner, Sven, Strauss, Hans-Georg, Wimberger, Pauline, Reuss, Alexander, and du Bois, Andreas
- Published
- 2015
- Full Text
- View/download PDF
28. Adjuvant Therapy in Lymph Node-Positive Vulvar Cancer: The AGO-CaRE-1 Study
- Author
-
Mahner, Sven, Jueckstock, Julia, Hilpert, Felix, Neuser, Petra, Harter, Philipp, de Gregorio, Nikolaus, Hasenburg, Annette, Sehouli, Jalid, Habermann, Annika, Hillemanns, Peter, Fuerst, Sophie, Strauss, Hans-Georg, Baumann, Klaus, Thiel, Falk, Mustea, Alexander, Meier, Werner, du Bois, Andreas, Griebel, Lis-Femke, and Woelber, Linn
- Published
- 2015
- Full Text
- View/download PDF
29. Genome-wide association study and functional follow-up identify 14q12 as a candidate risk locus for cervical cancer
- Author
-
Ramachandran, Dhanya, primary, Dennis, Joe, additional, Fachal, Laura, additional, Schürmann, Peter, additional, Bousset, Kristine, additional, Hülse, Fabienne, additional, Mao, Qianqian, additional, Wang, Yingying, additional, Jentschke, Matthias, additional, Böhmer, Gerd, additional, Strauß, Hans-Georg, additional, Hirchenhain, Christine, additional, Schmidmayr, Monika, additional, Müller, Florian, additional, Runnebaum, Ingo, additional, Hein, Alexander, additional, Stübs, Frederik, additional, Koch, Martin, additional, Ruebner, Matthias, additional, Beckmann, Matthias W, additional, Fasching, Peter A, additional, Luyten, Alexander, additional, Dürst, Matthias, additional, Hillemanns, Peter, additional, Easton, Douglas F, additional, and Dörk, Thilo, additional
- Published
- 2022
- Full Text
- View/download PDF
30. Adjuvant radiotherapy and local recurrence in vulvar cancer – a subset analysis of the AGO-CaRE-1 study
- Author
-
Woelber, Linn, primary, Prieske, Katharina, additional, Eulenburg, Christine zu, additional, Corradini, Stefanie, additional, Petersen, Cordula, additional, Bommert, Mareike, additional, Blankenstein, Thomas, additional, Hilpert, Felix, additional, de Gregorio, Nikolaus, additional, Iborra, Severine, additional, Sehouli, Jalid, additional, Ignatov, Atanas, additional, Hillemanns, Peter, additional, Fuerst, Sophie, additional, Strauss, Hans-Georg, additional, Baumann, Klaus, additional, Beckmann, Matthias W., additional, Mustea, Alexander, additional, Mahner, Sven, additional, and Jaeger, Anna, additional
- Published
- 2022
- Full Text
- View/download PDF
31. p53 and p16 expression profiles in vulvar cancer: a translational analysis by the Arbeitsgemeinschaft Gynäkologische Onkologie Chemo and Radiotherapy in Epithelial Vulvar Cancer study group
- Author
-
Woelber, Linn, primary, Prieske, Katharina, additional, Eulenburg, Christine, additional, Oliveira-Ferrer, Leticia, additional, de Gregorio, Nikolaus, additional, Klapdor, Ruediger, additional, Kalder, Matthias, additional, Braicu, Iona, additional, Fuerst, Sophie, additional, Klar, Maximilian, additional, Strauss, Hans-Georg, additional, Beckmann, Matthias, additional, Meier, Werner, additional, Ignatov, Atanas, additional, Mustea, Alexander, additional, Jueckstock, Julia, additional, Schmidt, Georg, additional, Bauerschlag, Dirk, additional, Hellriegel, Martin, additional, Canzler, Ulrich, additional, Petry, Karl Ulrich, additional, Kommoss, Stefan, additional, Hantschmann, Peer, additional, Heubner, Martin, additional, Mahner, Sven, additional, and Burandt, Eike, additional
- Published
- 2021
- Full Text
- View/download PDF
32. Uptake of hysterectomy and bilateral salpingooophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
- Author
-
Seppala, Toni T., Dominguez-Valentin, Mev, Crosbie, Emma J., Engel, Christoph, Aretz, Stefan, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Hovig, Eivind, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria G., Cavestro, Giulia M., Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Strauss, Hans-Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka-Pekka, Plazzer, John-Paul, Pineda, Marta, Navarro, Matilde, Vida, Joan B., Kariv, Revital, Rosner, Guy, Pinero, Tamara A., Pavicic, Walter, Kalfayan, Pablo, Ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Burn, John, Greenblatt, Marc, Cappel, Wouter H. de Vos Tot Nederveen, Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Buettner, Reinhard, Goergens, Heike, Morak, Monika, Holzapfel, Stefanie, Hueneburg, Robert, Doeberitz, Magnus von Knebel, Loeffler, Markus, Redler, Silke, Weitz, Jurgen, Pylvaenaeinen, Kirsi, Renkonen-Sinisalo, Laura, Lepisto, Anna, Hopper, John L., Win, Aung K., Lindor, Noralane M., Gallinger, Steven, Marchand, Loic Le, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Wadt, Karin A. W., Mourits, Marian J. E., Ketabi, Zohreh, Denton, Oliver G., Rodland, Einar A., Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Moeslein, Gabriela, Rokkones, Erik, Sampson, Julian R., Evans, D. G., Moller, Pal, Seppala, Toni T., Dominguez-Valentin, Mev, Crosbie, Emma J., Engel, Christoph, Aretz, Stefan, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Hovig, Eivind, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria G., Cavestro, Giulia M., Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Strauss, Hans-Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka-Pekka, Plazzer, John-Paul, Pineda, Marta, Navarro, Matilde, Vida, Joan B., Kariv, Revital, Rosner, Guy, Pinero, Tamara A., Pavicic, Walter, Kalfayan, Pablo, Ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Burn, John, Greenblatt, Marc, Cappel, Wouter H. de Vos Tot Nederveen, Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Buettner, Reinhard, Goergens, Heike, Morak, Monika, Holzapfel, Stefanie, Hueneburg, Robert, Doeberitz, Magnus von Knebel, Loeffler, Markus, Redler, Silke, Weitz, Jurgen, Pylvaenaeinen, Kirsi, Renkonen-Sinisalo, Laura, Lepisto, Anna, Hopper, John L., Win, Aung K., Lindor, Noralane M., Gallinger, Steven, Marchand, Loic Le, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Wadt, Karin A. W., Mourits, Marian J. E., Ketabi, Zohreh, Denton, Oliver G., Rodland, Einar A., Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Moeslein, Gabriela, Rokkones, Erik, Sampson, Julian R., Evans, D. G., and Moller, Pal
- Abstract
Purpose: This study aimed to report the uptake of hysterectomy and/or bilateral salpingo-oophorectomy (BSO) to prevent gynaecological cancers (risk-reducing surgery [RRS]) in carriers of pathogenic MMR (path_MMR) variants. Methods: The Prospective Lynch Syndrome Database (PLSD) was used to investigate RRS by a cross-sectional study in 2292 female path_MMR carriers aged 30-69 years. Results: Overall, 144, 79, and 517 carriers underwent risk-reducing hysterectomy, BSO, or both combined, respectively. Two-thirds of procedures before 50 years of age were combined hysterectomy and BSO, and 81% of all procedures included BSO. Risk-reducing hysterectomy was performed before age 50 years in 28%, 25%, 15%, and 9%, and BSO in 26%, 25%, 14% and 13% of path_MLH1, path_MSH2, path_MSH6, and path_PMS2 carriers, respectively. Before 50 years of age, 107 of 188 (57%) BSO and 126 of 204 (62%) hysterectomies were performed in women without any prior cancer, and only 5% (20/392) were performed simultaneously with colorectal cancer (CRC) surgery. Conclusion: Uptake of RRS before 50 years of age was low, and RRS was rarely undertaken in association with surgical treatment of CRC. Uptake of RRS aligned poorly with gene-and age-associated risk estimates for endometrial or ovarian cancer that were published recently from PLSD and did not correspond well with current clinical guidelines. The reasons should be clarified. Decision-making on opting for or against RRS and its timing should be better aligned with predicted risk and mortality for endometrial and ovarian cancer in Lynch syn-drome to improve outcomes. (C) 2021 The Author(s). Published by Elsevier Ltd.
- Published
- 2021
33. Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants:a Prospective Lynch Syndrome Database report
- Author
-
Seppälä, Toni T., Dominguez-Valentin, Mev, Crosbie, Emma J., Engel, Christoph, Aretz, Stefan, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Hovig, Eivind, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria G., Cavestro, Giulia M., Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Strauß, Hans Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka Pekka, Plazzer, John Paul, Pineda, Marta, Navarro, Matilde, Vida, Joan B., Kariv, Revital, Rosner, Guy, Piñero, Tamara A., Pavicic, Walter, Kalfayan, Pablo, ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Burn, John, Greenblatt, Marc, de Vos tot Nederveen Cappel, Wouter H., Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Büttner, Reinhard, Görgens, Heike, Morak, Monika, Holzapfel, Stefanie, Hüneburg, Robert, von Knebel Doeberitz, Magnus, Loeffler, Markus, Redler, Silke, Weitz, Jürgen, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Lepistö, Anna, Hopper, John L., Win, Aung K., Lindor, Noralane M., Gallinger, Steven, Le Marchand, Loïc, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Wadt, Karin A.W., Mourits, Marian J.E., Ketabi, Zohreh, Denton, Oliver G., Rødland, Einar A., Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Möslein, Gabriela, Rokkones, Erik, Sampson, Julian R., Evans, D. G., Møller, Pål, Seppälä, Toni T., Dominguez-Valentin, Mev, Crosbie, Emma J., Engel, Christoph, Aretz, Stefan, Macrae, Finlay, Winship, Ingrid, Capella, Gabriel, Thomas, Huw, Hovig, Eivind, Nielsen, Maartje, Sijmons, Rolf H., Bertario, Lucio, Bonanni, Bernardo, Tibiletti, Maria G., Cavestro, Giulia M., Mints, Miriam, Gluck, Nathan, Katz, Lior, Heinimann, Karl, Vaccaro, Carlos A., Green, Kate, Lalloo, Fiona, Hill, James, Schmiegel, Wolff, Vangala, Deepak, Perne, Claudia, Strauß, Hans Georg, Tecklenburg, Johanna, Holinski-Feder, Elke, Steinke-Lange, Verena, Mecklin, Jukka Pekka, Plazzer, John Paul, Pineda, Marta, Navarro, Matilde, Vida, Joan B., Kariv, Revital, Rosner, Guy, Piñero, Tamara A., Pavicic, Walter, Kalfayan, Pablo, ten Broeke, Sanne W., Jenkins, Mark A., Sunde, Lone, Bernstein, Inge, Burn, John, Greenblatt, Marc, de Vos tot Nederveen Cappel, Wouter H., Della Valle, Adriana, Lopez-Koestner, Francisco, Alvarez, Karin, Büttner, Reinhard, Görgens, Heike, Morak, Monika, Holzapfel, Stefanie, Hüneburg, Robert, von Knebel Doeberitz, Magnus, Loeffler, Markus, Redler, Silke, Weitz, Jürgen, Pylvänäinen, Kirsi, Renkonen-Sinisalo, Laura, Lepistö, Anna, Hopper, John L., Win, Aung K., Lindor, Noralane M., Gallinger, Steven, Le Marchand, Loïc, Newcomb, Polly A., Figueiredo, Jane C., Thibodeau, Stephen N., Therkildsen, Christina, Wadt, Karin A.W., Mourits, Marian J.E., Ketabi, Zohreh, Denton, Oliver G., Rødland, Einar A., Vasen, Hans, Neffa, Florencia, Esperon, Patricia, Tjandra, Douglas, Möslein, Gabriela, Rokkones, Erik, Sampson, Julian R., Evans, D. G., and Møller, Pål
- Abstract
Purpose: This study aimed to report the uptake of hysterectomy and/or bilateral salpingo-oophorectomy (BSO) to prevent gynaecological cancers (risk-reducing surgery [RRS]) in carriers of pathogenic MMR (path_MMR) variants. Methods: The Prospective Lynch Syndrome Database (PLSD) was used to investigate RRS by a cross-sectional study in 2292 female path_MMR carriers aged 30–69 years. Results: Overall, 144, 79, and 517 carriers underwent risk-reducing hysterectomy, BSO, or both combined, respectively. Two-thirds of procedures before 50 years of age were combined hysterectomy and BSO, and 81% of all procedures included BSO. Risk-reducing hysterectomy was performed before age 50 years in 28%, 25%, 15%, and 9%, and BSO in 26%, 25%, 14% and 13% of path_MLH1, path_MSH2, path_MSH6, and path_PMS2 carriers, respectively. Before 50 years of age, 107 of 188 (57%) BSO and 126 of 204 (62%) hysterectomies were performed in women without any prior cancer, and only 5% (20/392) were performed simultaneously with colorectal cancer (CRC) surgery. Conclusion: Uptake of RRS before 50 years of age was low, and RRS was rarely undertaken in association with surgical treatment of CRC. Uptake of RRS aligned poorly with gene- and age-associated risk estimates for endometrial or ovarian cancer that were published recently from PLSD and did not correspond well with current clinical guidelines. The reasons should be clarified. Decision-making on opting for or against RRS and its timing should be better aligned with predicted risk and mortality for endometrial and ovarian cancer in Lynch syndrome to improve outcomes.
- Published
- 2021
34. Pelvine Lymphonodektomie beim Vulvakarzinom - Wohl oder Übel?
- Author
-
Woelber, Linn, Bommert, Mareike, Prieske, Katharina, Fischer, Inger, Zu Eulenburg, Christine, Vettorazzi, Eik, Harter, Philipp, Jueckstock, Julia, Hilpert, Felix, De Gregorio, Niko, Iborra, Severine, Sehouli, Jalid, Ignatov, Atanas, Hillemanns, Peter, Fuerst, Sophie, Strauss, Hans Georg, Baumann, Klaus, Beckmann, Matthias, Mustea, Alexander, Meier, Werner, Wimberger, Pauline, Hanker, Lars, Canzler, Ulrich, Fehm, Tanja, Luyten, Alexander, Hellriegel, Martin, Kosse, Jens, Heiss, Christoph, Hantschmann, Peer, Mallmann, Peter, Tanner, Berno, Pfisterer, Jacobus, Mahner, Sven, Schmalfeldt, Barbara, and Jaeger, Anna
- Subjects
recurrence ,vulvar cancer ,lymph node metastasis ,pelvic lymphadenectomy ,prognosis - Abstract
Since the publication of the updated German guideline in 2015, the recommendations for performing pelvic lymphadenectomy (LAE) in patients with vulvar cancer (VSCC) have changed considerably. The guideline recommends surgical lymph node staging in all patients with a higher risk of pelvic lymph node involvement. However, the current data do not allow the population at risk to be clearly defined, therefore, the indication for pelvic lymphadenectomy is still not clear. There are currently two published German patient populations who had pelvic LAE which can be used to investigate both the prognostic effect of histologically verified pelvic lymph node metastasis and the relation between inguinal and pelvic lymph node involvement. A total of 1618 patients with primary FIGO stage ≥ IB VSCC were included in the multicenter AGO CaRE-1 study (1998-2008), 70 of whom underwent pelvic LAE. During a retrospective single-center evaluation carried out at the University Medical Center Hamburg-Eppendorf (UKE), a total of 514 patients with primary VSCC treated between 1996-2018 were evaluated, 21 of whom underwent pelvic LAE. In both cohorts, around 80% of the patients who underwent pelvic LAE were inguinally node-positive, with a median number of three affected groin lymph nodes. There were no cases of pelvic lymph node metastasis without inguinal lymph node metastasis in either of the two cohorts. Between 33-35% of the inguinal node-positive patients also had pelvic lymph node metastasis; the median number of affected groin lymph nodes in these patients was high (> 4), and the maximum median diameter of the largest inguinal metastasis was > 40 mm in both cohorts. Pelvic lymph node staging and pelvic radiotherapy is therefore probably not necessary for the majority of node-positive patients with VSCC, as the relevant risk of pelvic lymph node involvement was primarily found in node-positive patients with high-grade disease. More, ideally prospective data collections are necessary to validate the relation between inguinal and pelvic lymph node involvement.
- Published
- 2020
35. Association of genomic variants atPAX8andPBX2with cervical cancer risk
- Author
-
Ramachandran, Dhanya, primary, Wang, Yingying, additional, Schürmann, Peter, additional, Hülse, Fabienne, additional, Mao, Qianqian, additional, Jentschke, Matthias, additional, Böhmer, Gerd, additional, Strauß, Hans‐Georg, additional, Hirchenhain, Christine, additional, Schmidmayr, Monika, additional, Müller, Florian, additional, Runnebaum, Ingo, additional, Hein, Alexander, additional, Koch, Martin, additional, Ruebner, Matthias, additional, Beckmann, Matthias W., additional, Fasching, Peter A., additional, Luyten, Alexander, additional, Dürst, Matthias, additional, Hillemanns, Peter, additional, and Dörk, Thilo, additional
- Published
- 2021
- Full Text
- View/download PDF
36. Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
- Author
-
Seppälä, Toni T., primary, Dominguez-Valentin, Mev, additional, Crosbie, Emma J., additional, Engel, Christoph, additional, Aretz, Stefan, additional, Macrae, Finlay, additional, Winship, Ingrid, additional, Capella, Gabriel, additional, Thomas, Huw, additional, Hovig, Eivind, additional, Nielsen, Maartje, additional, Sijmons, Rolf H., additional, Bertario, Lucio, additional, Bonanni, Bernardo, additional, Tibiletti, Maria G., additional, Cavestro, Giulia M., additional, Mints, Miriam, additional, Gluck, Nathan, additional, Katz, Lior, additional, Heinimann, Karl, additional, Vaccaro, Carlos A., additional, Green, Kate, additional, Lalloo, Fiona, additional, Hill, James, additional, Schmiegel, Wolff, additional, Vangala, Deepak, additional, Perne, Claudia, additional, Strauß, Hans-Georg, additional, Tecklenburg, Johanna, additional, Holinski-Feder, Elke, additional, Steinke-Lange, Verena, additional, Mecklin, Jukka-Pekka, additional, Plazzer, John-Paul, additional, Pineda, Marta, additional, Navarro, Matilde, additional, Vida, Joan B., additional, Kariv, Revital, additional, Rosner, Guy, additional, Piñero, Tamara A., additional, Pavicic, Walter, additional, Kalfayan, Pablo, additional, ten Broeke, Sanne W., additional, Jenkins, Mark A., additional, Sunde, Lone, additional, Bernstein, Inge, additional, Burn, John, additional, Greenblatt, Marc, additional, de Vos tot Nederveen Cappel, Wouter H., additional, Della Valle, Adriana, additional, Lopez-Koestner, Francisco, additional, Alvarez, Karin, additional, Büttner, Reinhard, additional, Görgens, Heike, additional, Morak, Monika, additional, Holzapfel, Stefanie, additional, Hüneburg, Robert, additional, von Knebel Doeberitz, Magnus, additional, Loeffler, Markus, additional, Redler, Silke, additional, Weitz, Jürgen, additional, Pylvänäinen, Kirsi, additional, Renkonen-Sinisalo, Laura, additional, Lepistö, Anna, additional, Hopper, John L., additional, Win, Aung K., additional, Lindor, Noralane M., additional, Gallinger, Steven, additional, Le Marchand, Loïc, additional, Newcomb, Polly A., additional, Figueiredo, Jane C., additional, Thibodeau, Stephen N., additional, Therkildsen, Christina, additional, Wadt, Karin A.W., additional, Mourits, Marian J.E., additional, Ketabi, Zohreh, additional, Denton, Oliver G., additional, Rødland, Einar A., additional, Vasen, Hans, additional, Neffa, Florencia, additional, Esperon, Patricia, additional, Tjandra, Douglas, additional, Möslein, Gabriela, additional, Rokkones, Erik, additional, Sampson, Julian R., additional, Evans, D.G., additional, and Møller, Pål, additional
- Published
- 2021
- Full Text
- View/download PDF
37. Pelvic Lymphadenectomy in Vulvar Cancer – Does it make sense?
- Author
-
Woelber, Linn, additional, Bommert, Mareike, additional, Prieske, Katharina, additional, Fischer, Inger, additional, zu Eulenburg, Christine, additional, Vettorazzi, Eik, additional, Harter, Philipp, additional, Jueckstock, Julia, additional, Hilpert, Felix, additional, de Gregorio, Niko, additional, Iborra, Severine, additional, Sehouli, Jalid, additional, Ignatov, Atanas, additional, Hillemanns, Peter, additional, Fuerst, Sophie, additional, Strauss, Hans-Georg, additional, Baumann, Klaus, additional, Beckmann, Matthias, additional, Mustea, Alexander, additional, Meier, Werner, additional, Wimberger, Pauline, additional, Hanker, Lars, additional, Canzler, Ulrich, additional, Fehm, Tanja, additional, Luyten, Alexander, additional, Hellriegel, Martin, additional, Kosse, Jens, additional, Heiss, Christoph, additional, Hantschmann, Peer, additional, Mallmann, Peter, additional, Tanner, Berno, additional, Pfisterer, Jacobus, additional, Mahner, Sven, additional, Schmalfeldt, Barbara, additional, and Jaeger, Anna, additional
- Published
- 2020
- Full Text
- View/download PDF
38. Chemoradiation in Cervical Cancer with Cisplatin and High-Dose Rate Brachytherapy Combined with External Beam Radiotherapy Results of a Phase-II Study: Results of a Phase-II Study
- Author
-
Strauss, Hans-Georg, Kuhnt, Thomas, Laban, Cornelia, Puschmann, Daniela, Pigorsch, Steffi, Dunst, Juergen, Koelbl, Heinz, and Haensgen, Gabriele
- Published
- 2002
- Full Text
- View/download PDF
39. Ezrin expression is related to poor prognosis in FIGO stage I endometrioid carcinomas
- Author
-
Köbel, Martin, Langhammer, Tina, Hüttelmaier, Stefan, Schmitt, Wolfgang D, Kriese, Karen, Dittmer, Jürgen, Strauss, Hans-Georg, Thomssen, Christoph, and Hauptmann, Steffen
- Published
- 2006
- Full Text
- View/download PDF
40. IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer
- Author
-
Bley, Nadine, primary, Schott, Annekatrin, additional, Müller, Simon, additional, Misiak, Danny, additional, Lederer, Marcell, additional, Fuchs, Tommy, additional, Aßmann, Chris, additional, Glaß, Markus, additional, Ihling, Christian, additional, Sinz, Andrea, additional, Pazaitis, Nikolaos, additional, Wickenhauser, Claudia, additional, Vetter, Martina, additional, Ungurs, Olga, additional, Strauss, Hans-Georg, additional, Thomssen, Christoph, additional, and Hüttelmaier, Stefan, additional
- Published
- 2020
- Full Text
- View/download PDF
41. Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
- Author
-
Dominguez-Valentin, Mev, primary, Seppälä, Toni T., additional, Engel, Christoph, additional, Aretz, Stefan, additional, Macrae, Finlay, additional, Winship, Ingrid, additional, Capella, Gabriel, additional, Thomas, Huw, additional, Hovig, Eivind, additional, Nielsen, Maartje, additional, Sijmons, Rolf H, additional, Bertario, Lucio, additional, Bonanni, Bernardo, additional, Tibiletti, Maria Grazia, additional, Cavestro, Giulia Martina, additional, Mints, Miriam, additional, Gluck, Nathan, additional, Katz, Lior, additional, Heinimann, Karl, additional, Vaccaro, Carlos A., additional, Green, Kate, additional, Lalloo, Fiona, additional, Hill, James, additional, Schmiegel, Wolff, additional, Vangala, Deepak, additional, Perne, Claudia, additional, Strauß, Hans-Georg, additional, Tecklenburg, Johanna, additional, Holinski-Feder, Elke, additional, Steinke-Lange, Verena, additional, Mecklin, Jukka-Pekka, additional, Plazzer, John-Paul, additional, Pineda, Marta, additional, Navarro, Matilde, additional, Vidal, Joan Brunet, additional, Kariv, Revital, additional, Rosner, Guy, additional, Piñero, Tamara Alejandra, additional, Gonzalez, María Laura, additional, Kalfayan, Pablo, additional, Sampson, Julian R., additional, Ryan, Neil A. J., additional, Evans, D. Gareth, additional, Møller, Pål, additional, and Crosbie, Emma J., additional
- Published
- 2020
- Full Text
- View/download PDF
42. Association of genomic variants at the human leukocyte antigen locus with cervical cancer risk, HPV status and gene expression levels
- Author
-
Ramachandran, Dhanya, primary, Schürmann, Peter, additional, Mao, Qianqian, additional, Wang, Yingying, additional, Bretschneider, Lisa‐Marie, additional, Speith, Lisa‐Marie, additional, Hülse, Fabienne, additional, Enßen, Julia, additional, Bousset, Kristine, additional, Jentschke, Matthias, additional, Böhmer, Gerd, additional, Strauß, Hans‐Georg, additional, Hirchenhain, Christine, additional, Schmidmayr, Monika, additional, Tarbiat, Johanna, additional, Runnebaum, Ingo, additional, Dürst, Matthias, additional, Hein, Alexander, additional, Koch, Martin, additional, Ruebner, Matthias, additional, Ekici, Arif, additional, Beckmann, Matthias W., additional, Fasching, Peter A., additional, Luyten, Alexander, additional, Petry, Karl‐Ulrich, additional, Hillemanns, Peter, additional, and Dörk, Thilo, additional
- Published
- 2020
- Full Text
- View/download PDF
43. Evaluation of treatment patterns and prognosis in correlation with age in patients with vulvar cancer: A subset analysis of the AGO-CaRE-1 study.
- Author
-
Prieske, Katharina, primary, Woelber, Linn Lena, additional, Muallem, Mustafa Zelal, additional, Eulenburg, Christine, additional, Jueckstock, Julia Kathrin, additional, Hilpert, Felix, additional, de Gregorio, Nikolaus, additional, Iborra, Severine, additional, Ignatov, Atanas, additional, Hillemanns, Peter, additional, Fuerst, Sophie, additional, Strauss, Hans-Georg, additional, Baumann, Klaus, additional, Thiel, Falk, additional, Mustea, Alexander, additional, Meier, Werner, additional, Harter, Philipp, additional, Wimberger, Pauline, additional, Sehouli, Jalid, additional, and Mahner, Sven, additional
- Published
- 2020
- Full Text
- View/download PDF
44. Bevacizumab and platinum-based combinations for recurrent ovarian cancer: a randomised, open-label, phase 3 trial
- Author
-
Pfisterer, Jacobus, primary, Shannon, Catherine M, additional, Baumann, Klaus, additional, Rau, Joern, additional, Harter, Philipp, additional, Joly, Florence, additional, Sehouli, Jalid, additional, Canzler, Ulrich, additional, Schmalfeldt, Barbara, additional, Dean, Andrew P, additional, Hein, Alexander, additional, Zeimet, Alain G, additional, Hanker, Lars C, additional, Petit, Thierry, additional, Marmé, Frederik, additional, El-Balat, Ahmed, additional, Glasspool, Rosalind, additional, de Gregorio, Nikolaus, additional, Mahner, Sven, additional, Meniawy, Tarek M, additional, Park-Simon, Tjoung-Won, additional, Mouret-Reynier, Marie-Ange, additional, Costan, Cristina, additional, Meier, Werner, additional, Reinthaller, Alexander, additional, Goh, Jeffrey C, additional, L'Haridon, Tifenn, additional, Baron Hay, Sally, additional, Kommoss, Stefan, additional, du Bois, Andreas, additional, Kurtz, Jean-Emmanuel, additional, Ackermann, Sven, additional, Anthuber, Christoph, additional, Aydogdu, Mustafa, additional, Baldauf, Angelika, additional, Bauer, Wolfgang, additional, Behringer, Dirk, additional, Belau, Antje, additional, Bender, Alexandra, additional, Brucker, Cosima, additional, Burges, Alexander, additional, Daabach, Trygve, additional, Denschlag, Dominik, additional, Deryal, Mustafa, additional, Dörfel, Steffen, additional, Ebert, Juliane, additional, Fehm, Tanja, additional, Feidicker, Susanne Maria, additional, Feisel-Schwickardi, Gabriele, additional, Felberbaum, Ricardo, additional, Frank, Matthias, additional, Gebauer, Gerhard, additional, Gerber, Bernd, additional, Gerhardt, Axel, additional, Grafe, Andrea, additional, Griesshammer, Martin, additional, Grischke, Eva-Maria, additional, Gröll, Isolde, additional, Gropp-Meier, Martina, additional, Hager, Dietrich, additional, Hanf, Volker, additional, Hannig, Carla Verena, additional, Hantschmann, Peer, additional, Hauzenberger, Tanja, additional, Herwig, Uwe, additional, Heubner, Martin, additional, Hielscher, Carsten, additional, Hilpert, Felix, additional, Hitschold, Thomas, additional, Hofmann, Manfred, additional, Jackisch, Christian, additional, Janni, Wolfgang, additional, Kiesel, Ludwig, additional, Ko, Yon-Dschun, additional, Koch, Hans-Joachim, additional, Krabisch, Petra, additional, Krieger, Peter, additional, Kubin, Thomas, additional, Kühn, Thorsten, additional, Lampe, Björn, additional, Ledwon, Peter, additional, Lemster, Sabine, additional, Lex, Benno, additional, Liebrich, Clemens, additional, Lorenz, Ralf, additional, Lück, Hans-Joachim, additional, Mallmann, Peter, additional, Meinerz, Wolfgang, additional, Menke, Götz, additional, Möbus, Volker, additional, Müller, Thomas, additional, Müller, Volker, additional, Neunhöffer, Tanja, additional, Ober, Angelika, additional, Oskay-Özcelik, Gülten, additional, Ostertag, Horst, additional, Pölcher, Martin, additional, Rautenberg, Beate, additional, Rein, Daniel, additional, Reiter, Wilhelm, additional, Rempen, Andreas, additional, Runnebaum, Ingo, additional, Schmidt, Marcus, additional, Schnohr, Sabine, additional, Scholz, Heinz, additional, Schröder, Willibald, additional, Simon, Eike, additional, Sperfeld, Antje, additional, Steckkönig, Annette, additional, Strauß, Hans-Georg, additional, Stuth, Ronaldo, additional, Terhaag, Jürgen, additional, Thiel, Falk, additional, Thill, Marc, additional, Tomé, Oliver, additional, Uleer, Christoph, additional, Vogel, Susanne, additional, Voß, Hermann, additional, Weigel, Michael, additional, Winkler, Ulrich, additional, Wischnik, Arthur, additional, Zeiser, Tobias, additional, Zorr, Andreas, additional, Glasspool, Ros, additional, Hudson, Emma, additional, Jones, Rachel, additional, Lafleur, Judith, additional, Marth, Christian, additional, Petru, Edgar, additional, Antill, Yoland, additional, Azer, Mary, additional, Baron-Hay, Sally, additional, Beale, Philip, additional, Begbie, Stephen, additional, Black, Allison, additional, Briscoe, Karen, additional, Dean, Andrew, additional, Goh, Jeffrey, additional, Harvey, Sandra, additional, Lee, Chee, additional, Matos, Marco, additional, Meniawy, Tarek, additional, Olesen, Inger, additional, Shannon, Catherine, additional, Vasey, Paul, additional, Abadie-Lacourtoisie, Sophie, additional, Arsene, Olivier, additional, Barthier, Sophie, additional, Becuwe-Roemer, Célia, additional, Berton-Rigaud, Dominique, additional, Cappiello-Bataller, Maria, additional, Catala, Stéphanie, additional, Del Piano, Francesco, additional, Deplanque, Gaël, additional, Despax, Raymond, additional, Dohollou, Nadine, additional, Garnier-Tixidré, Claire, additional, Grenier, Julien, additional, Guardiola, Emmanuel, additional, Hardy-Bessard, Anne-Claire, additional, Lefeuvre-Plesse, Claudia, additional, Leheurteur, Marianne, additional, Lesoin, Anne, additional, Levache, Charles-Briac, additional, Longo, Raffaele, additional, Lortholary, Alain, additional, Meunier, Jérôme, additional, Raban, Nadia, additional, Romano, Olivier, additional, Vannetzel, Jean-Michel, additional, and Zannetti, Alain, additional
- Published
- 2020
- Full Text
- View/download PDF
45. Sarcoma of the Uterus. Guideline of the DGGG and OEGGG (S2k Level, AWMF Register Number 015/074, February 2019)
- Author
-
Denschlag, Dominik, Ackermann, Sven, Battista, Marco Johannes, Cremer, Wolfgang, Egerer, Gerlinde, Follmann, Markus, Haas, Heidemarie, Harter, Philipp, Hettmer, Simone, Horn, Lars-Christian, Juhasz-Boess, Ingolf, Kast, Karin, Koehler, Gunter, Kroencke, Thomas, Lindel, Katja, Mallmann, Peter, Meyer-Steinacker, Regine, Mustea, Alexander, Petru, Edgar, Reichardt, Peter, Schmidt, Dietmar, Strauss, Hans-Georg, Tempfer, Clemens, Thiel, Falk, Ulrich, Uwe, Vogl, Thomas, Vordermark, Dirk, Gass, Paul, Beckmann, Matthias W., Denschlag, Dominik, Ackermann, Sven, Battista, Marco Johannes, Cremer, Wolfgang, Egerer, Gerlinde, Follmann, Markus, Haas, Heidemarie, Harter, Philipp, Hettmer, Simone, Horn, Lars-Christian, Juhasz-Boess, Ingolf, Kast, Karin, Koehler, Gunter, Kroencke, Thomas, Lindel, Katja, Mallmann, Peter, Meyer-Steinacker, Regine, Mustea, Alexander, Petru, Edgar, Reichardt, Peter, Schmidt, Dietmar, Strauss, Hans-Georg, Tempfer, Clemens, Thiel, Falk, Ulrich, Uwe, Vogl, Thomas, Vordermark, Dirk, Gass, Paul, and Beckmann, Matthias W.
- Abstract
Aims This is an official guideline published and coordinated by the German Society of Gynecology and Obstetrics (DGGG) and the Austrian Society of Gynecology and Obstetrics (OEGGG). Because of their rarity and heterogeneous histopathology, uterine sarcomas are challenging in terms of how they should be managed clinically, and treatment requires a multidisciplinary approach. To our knowledge, there are currently no binding evidence-based recommendations for the appropriate management of this heterogeneous group of tumors. Methods This S2k guideline was first published in 2015. The update published here is the result of the consensus of a representative interdisciplinary group of experts who carried out a systematic search of the literature on uterine sarcomas in the context of the guidelines program of the DGGG, OEGGG and SGGG. Members of the participating professional societies achieved a formal consensus after a moderated structured consensus process. Recommendations The consensus-based recommendations and statements include the epidemiology, classification, staging, symptoms, general diagnostic work-up and general pathology of uterine sarcomas as well as the genetic predisposition to develop uterine sarcomas. Also included are statements on the management of leiomyosarcomas, (low and high-grade) endometrial stromal sarcomas and undifferentiated uterine sarcomas and adenosarcomas. Finally, the guideline considers the follow-up and morcellation of uterine sarcomas and the information provided to patients.
- Published
- 2019
46. Significance of endovaginal ultrasonography in assessing tamoxifen-associated changes of the endometrium: A prospective study
- Author
-
Strauss, Hans-Georg, Wolters, Matthias, Methfessel, Gisela, Buchmann, Juergen, and Koelbl, Heinz
- Published
- 2000
47. Association of genomic variants at PAX8 and PBX2 with cervical cancer risk.
- Author
-
Ramachandran, Dhanya, Wang, Yingying, Schürmann, Peter, Hülse, Fabienne, Mao, Qianqian, Jentschke, Matthias, Böhmer, Gerd, Strauß, Hans‐Georg, Hirchenhain, Christine, Schmidmayr, Monika, Müller, Florian, Runnebaum, Ingo, Hein, Alexander, Koch, Martin, Ruebner, Matthias, Beckmann, Matthias W., Fasching, Peter A., Luyten, Alexander, Dürst, Matthias, and Hillemanns, Peter
- Subjects
DISEASE risk factors ,CERVICAL cancer ,GENOME-wide association studies ,CERVICAL intraepithelial neoplasia ,GENETIC variation ,CANCER invasiveness - Abstract
Cervical malignancy is triggered by human papillomavirus infection but the risk for cervical cancer has a hereditary component. From a recent Genome Wide Association Study meta‐analysis, 2q14.1 (PAX8) and 6p21.32 (PBX2) have been proposed as novel cervical cancer susceptibility loci. We investigated the two main signals at these loci in an independent case‐control series of 2578 cases with cervical dysplasia or carcinoma and 1483 healthy females. We find significant associations for both variants, rs10175462 at PAX8 and rs2856437 at PBX2, with overall cervical disease (rs10175462: odds ratio [OR] 0.82, 95% confidence interval [CI] 0.74‐0.91, P = 2.4 × 10−4; rs2856437: OR 1.52, 95% CI 1.14‐2.02, P =.004). Both variants showed evidence of association with invasive squamous cervical cancer (rs10175462: OR 0.80, 95% CI 0.68‐0.94, P =.006; rs2856437: OR 1.56, 95% CI 1.03‐2.36, P =.036) and with high‐grade dysplasia (rs10175462: OR 0.79, 95%CI 0.70‐0.90, P = 1.9 × 10−4; rs2856437: OR 1.58, 95% CI 1.15‐2.17, P =.005). A combined analysis of high‐grade dysplasia and invasive cervical cancer also showed significant associations for both variants (rs10175462: OR 0.81, 95% CI 0.73‐0.91, P = 2.4 × 10−4; rs2856437: OR 1.57, 95% CI 1.18‐2.10, P =.002). No association was detected for rs2856437 with low‐grade dysplasia, while rs10175462 showed weak evidence of association (P =.05). RNA analyses in cervical samples revealed that PAX8 transcripts were upregulated in HPV‐positive lesions (P =.008) but this was not observed in the presence of the protective minor allele of rs10175462. The rs10175462 genotype also correlated with reduced levels of the lncRNA PAX8‐AS1 (P <.001). Taken together, our results extend the evidence for a link between genomic risk variants at the HLA region (PBX2) with cervical disease and support PAX8 as the first consistent non‐HLA cervical cancer susceptibility locus. What's new? High‐risk HPV is a major trigger of cervical cancer, but only some women are susceptible. Here, the authors investigated two genetic variants recently identified in genome‐wide association studies as possibly related to cervical cancer risk. The variants are located in the genes PAX8 and PBX2. This study tested the association in a German population containing 1122 cases of invasive cervical cancer, 1384 cases of cervical dysplasia, and 1483 controls. Both variants showed an association with cervical cancer and high‐grade cervical dysplasia. RNA analysis also revealed that the PAX8 variants influenced the amount of transcript found in cervical samples. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
48. Sarcoma of the Uterus. Guideline of the DGGG and OEGGG (S2k Level, AWMF Register Number 015/074, February 2019)
- Author
-
Denschlag, Dominik, additional, Ackermann, Sven, additional, Battista, Marco Johannes, additional, Cremer, Wolfgang, additional, Egerer, Gerlinde, additional, Follmann, Markus, additional, Haas, Heidemarie, additional, Harter, Philipp, additional, Hettmer, Simone, additional, Horn, Lars-Christian, additional, Juhasz-Boess, Ingolf, additional, Kast, Karin, additional, Köhler, Günter, additional, Kröncke, Thomas, additional, Lindel, Katja, additional, Mallmann, Peter, additional, Meyer-Steinacker, Regine, additional, Mustea, Alexander, additional, Petru, Edgar, additional, Reichardt, Peter, additional, Schmidt, Dietmar, additional, Strauss, Hans-Georg, additional, Tempfer, Clemens, additional, Thiel, Falk, additional, Ulrich, Uwe, additional, Vogl, Thomas, additional, Vordermark, Dirk, additional, Gass, Paul, additional, and Beckmann, Matthias W., additional
- Published
- 2019
- Full Text
- View/download PDF
49. The influence of obesity on tumor recurrence in vulvar cancer patients.
- Author
-
Klapdor, Rüdiger, primary, Hillemanns, Peter, additional, Woelber, Linn Lena, additional, Jueckstock, Julia Kathrin, additional, Hilpert, Felix, additional, de Gregorio, Nikolaus, additional, Hasenburg, Annette, additional, Sehouli, Jalid, additional, Ignatov, Atanas, additional, Fuerst, Sophie, additional, Strauss, Hans-Georg, additional, Baumann, Klaus, additional, Thiel, Falk, additional, Mustea, Alexander, additional, Meier, Werner, additional, Harter, Philipp, additional, Wimberger, Pauline, additional, Hanker, Lars Christian, additional, Schmalfeldt, Barbara, additional, and Mahner, Sven, additional
- Published
- 2019
- Full Text
- View/download PDF
50. p53 and p16 expression profiles reveal three prognostically relevant subgroups in vulvar cancer: A TMA based study by the AGO-CaRE-translational study group.
- Author
-
Woelber, Linn Lena, primary, Prieske, Katharina, additional, Eulenburg, Christine, additional, de Gregorio, Nikolaus, additional, Klapdor, Rüdiger, additional, Kalder, Matthias, additional, Braicu, Elena Ioana, additional, Fuerst, Sophie, additional, Klar, Maximillian, additional, Strauss, Hans-Georg, additional, Mehlhorn, Grit, additional, Meier, Werner, additional, Ignatov, Atanas, additional, Mustea, Alexander, additional, Jueckstock, Julia Kathrin, additional, Schmidt, Georg, additional, Bauerschlag, Dirk, additional, Hellriegel, Martin, additional, Mahner, Sven, additional, and Burandt, Eike, additional
- Published
- 2019
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.