21 results on '"Strasser N"'
Search Results
2. P214 Clinical course of SARS-CoV-2 infections of paediatric patients with cystic fibrosis– a single retrospective centre experience
- Author
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Sieber, J., primary, Strasser, N., additional, Schmidthaler, K., additional, Dehlink, E., additional, Gaupmann, R., additional, Szépfalusi, Z., additional, and Gruber, S., additional
- Published
- 2023
- Full Text
- View/download PDF
3. MERLIN (MEthane Remote sensing LIdar missioN): heading towards PFM and observation of interesting effects
- Author
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Minoglou, Kyriaki, Karafolas, Nikos, Cugny, Bruno, Strasser, N., Wührer, C., Kühl, C., Haiml, M., Viehmann, D., and Kritzler, M.
- Published
- 2023
- Full Text
- View/download PDF
4. Long Term Outcome After Pediatric Lung Transplantation
- Author
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Gruber, S., primary, Nachbaur, E., additional, Strasser, N., additional, Castillo, T., additional, and Szépfalusi, Z., additional
- Published
- 2022
- Full Text
- View/download PDF
5. P371 The impact of elexacaftor/tezacaftor/ivacaftor on mental health in young children with cystic fibrosis.
- Author
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Gruber, S., Strasser, N., Appelt, D., Molnar, A., Gona-Höpler, L., Ohmann, S., Sackl-Pammer, P., Plener, P., Szepfalusi, Z., and Prinz, K.
- Subjects
- *
CYSTIC fibrosis , *CHILDREN'S health , *MENTAL health - Published
- 2024
- Full Text
- View/download PDF
6. P078 Case report: elexacaftor/tezacaftor/ivacaftor as a game changer in an individual with CFTR class II mutation N1303k
- Author
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Gona-Hoepler, L.M., Dehlink, E., Strasser, N., Nachbaur, E., and Gruber, S.
- Published
- 2023
- Full Text
- View/download PDF
7. Quality of Life after Pediatric Lung Transplantation
- Author
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Strasser, N., primary, Gruber, S., additional, Hoetzenecker, K., additional, Klepetko, W., additional, Szépfalusi, Z., additional, and Nachbaur, E., additional
- Published
- 2020
- Full Text
- View/download PDF
8. Optical In-Situ Monitor A Breadboard System to Enable Space-Based Optical Observation of Space Debris
- Author
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Utzmann, J., Ferreira, L., Strasser, N., Vives, G., Probst, Dieter, and Lievre, N.
- Subjects
520 Astronomy - Abstract
The goals of the ESA project "Optical In-Situ Monitor" are to design and integrate a breadboard of a space-based space debris camera and to develop and test its end-to-end processing chain. The corresponding future flight model shall be used for the detection of small-sized (down to 1 mm) space debris in LEO as well as larger objects in GEO. It is intended to be flown on a platform in sun-synchronous orbit near the terminator plane. The activity`s breadboard system is comprised of the following three main elements. Breadboard Instrument: acquires images of space debris scenes generated by the Test Set-Up with the characteristics of the future flight model instrument. Image processing pipeline: on-board debris detection and data reduction, on-ground astrometry and photometry. Test Set-Up: scene generator for space debris observation scenarios. The breadboard system will constitute a unique facility to perform realistic tests of the end-to-end chain for debris observations within a controlled environment. This chain starts from signal generation via the scene generator, is followed by the acquisition of images via the breadboard instrument and finally performs the data processing until the astrometric and photometric reduction step. High accuracy is required for the scene generation part regarding motion and photometric accuracy because it serves as ground-truth for the system. As prime contractor, Airbus Defence and Space is responsible fo project management, system and performance engineering, the breadboard instrument, and on-board data processing hardware issues. The required image processing software is being developed at the Astronomical Institute of the University of Bern (AIUB). Micos provides the space debris scene generator, emulating both debris and star background. The paper will provide an overview of requirements and the design of the three main elements as well as on the results of the end-to-end performance tests.
- Published
- 2018
- Full Text
- View/download PDF
9. MERLIN (MEthane Remote sensing LIdar missioN): heading towards PFM and observation of interesting effects.
- Author
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Strasser, N., Wührer, C., Kühl, C., Haiml, M., Viehmann, D., and Kritzler, M.
- Published
- 2024
- Full Text
- View/download PDF
10. The seventh blind test of crystal structure prediction: structure ranking methods.
- Author
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Hunnisett LM, Francia N, Nyman J, Abraham NS, Aitipamula S, Alkhidir T, Almehairbi M, Anelli A, Anstine DM, Anthony JE, Arnold JE, Bahrami F, Bellucci MA, Beran GJO, Bhardwaj RM, Bianco R, Bis JA, Boese AD, Bramley J, Braun DE, Butler PWV, Cadden J, Carino S, Červinka C, Chan EJ, Chang C, Clarke SM, Coles SJ, Cook CJ, Cooper RI, Darden T, Day GM, Deng W, Dietrich H, DiPasquale A, Dhokale B, van Eijck BP, Elsegood MRJ, Firaha D, Fu W, Fukuzawa K, Galanakis N, Goto H, Greenwell C, Guo R, Harter J, Helfferich J, Hoja J, Hone J, Hong R, Hušák M, Ikabata Y, Isayev O, Ishaque O, Jain V, Jin Y, Jing A, Johnson ER, Jones I, Jose KVJ, Kabova EA, Keates A, Kelly PF, Klimeš J, Kostková V, Li H, Lin X, List A, Liu C, Liu YM, Liu Z, Lončarić I, Lubach JW, Ludík J, Maryewski AA, Marom N, Matsui H, Mattei A, Mayo RA, Melkumov JW, Mladineo B, Mohamed S, Momenzadeh Abardeh Z, Muddana HS, Nakayama N, Nayal KS, Neumann MA, Nikhar R, Obata S, O'Connor D, Oganov AR, Okuwaki K, Otero-de-la-Roza A, Parkin S, Parunov A, Podeszwa R, Price AJA, Price LS, Price SL, Probert MR, Pulido A, Ramteke GR, Rehman AU, Reutzel-Edens SM, Rogal J, Ross MJ, Rumson AF, Sadiq G, Saeed ZM, Salimi A, Sasikumar K, Sekharan S, Shankland K, Shi B, Shi X, Shinohara K, Skillman AG, Song H, Strasser N, van de Streek J, Sugden IJ, Sun G, Szalewicz K, Tan L, Tang K, Tarczynski F, Taylor CR, Tkatchenko A, Touš P, Tuckerman ME, Unzueta PA, Utsumi Y, Vogt-Maranto L, Weatherston J, Wilkinson LJ, Willacy RD, Wojtas L, Woollam GR, Yang Y, Yang Z, Yonemochi E, Yue X, Zeng Q, Zhou T, Zhou Y, Zubatyuk R, and Cole JC
- Abstract
A seventh blind test of crystal structure prediction has been organized by the Cambridge Crystallographic Data Centre. The results are presented in two parts, with this second part focusing on methods for ranking crystal structures in order of stability. The exercise involved standardized sets of structures seeded from a range of structure generation methods. Participants from 22 groups applied several periodic DFT-D methods, machine learned potentials, force fields derived from empirical data or quantum chemical calculations, and various combinations of the above. In addition, one non-energy-based scoring function was used. Results showed that periodic DFT-D methods overall agreed with experimental data within expected error margins, while one machine learned model, applying system-specific AIMnet potentials, agreed with experiment in many cases demonstrating promise as an efficient alternative to DFT-based methods. For target XXXII, a consensus was reached across periodic DFT methods, with consistently high predicted energies of experimental forms relative to the global minimum (above 4 kJ mol
-1 at both low and ambient temperatures) suggesting a more stable polymorph is likely not yet observed. The calculation of free energies at ambient temperatures offered improvement of predictions only in some cases (for targets XXVII and XXXI). Several avenues for future research have been suggested, highlighting the need for greater efficiency considering the vast amounts of resources utilized in many cases., (open access.)- Published
- 2024
- Full Text
- View/download PDF
11. The seventh blind test of crystal structure prediction: structure generation methods.
- Author
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Hunnisett LM, Nyman J, Francia N, Abraham NS, Adjiman CS, Aitipamula S, Alkhidir T, Almehairbi M, Anelli A, Anstine DM, Anthony JE, Arnold JE, Bahrami F, Bellucci MA, Bhardwaj RM, Bier I, Bis JA, Boese AD, Bowskill DH, Bramley J, Brandenburg JG, Braun DE, Butler PWV, Cadden J, Carino S, Chan EJ, Chang C, Cheng B, Clarke SM, Coles SJ, Cooper RI, Couch R, Cuadrado R, Darden T, Day GM, Dietrich H, Ding Y, DiPasquale A, Dhokale B, van Eijck BP, Elsegood MRJ, Firaha D, Fu W, Fukuzawa K, Glover J, Goto H, Greenwell C, Guo R, Harter J, Helfferich J, Hofmann DWM, Hoja J, Hone J, Hong R, Hutchison G, Ikabata Y, Isayev O, Ishaque O, Jain V, Jin Y, Jing A, Johnson ER, Jones I, Jose KVJ, Kabova EA, Keates A, Kelly PF, Khakimov D, Konstantinopoulos S, Kuleshova LN, Li H, Lin X, List A, Liu C, Liu YM, Liu Z, Liu ZP, Lubach JW, Marom N, Maryewski AA, Matsui H, Mattei A, Mayo RA, Melkumov JW, Mohamed S, Momenzadeh Abardeh Z, Muddana HS, Nakayama N, Nayal KS, Neumann MA, Nikhar R, Obata S, O'Connor D, Oganov AR, Okuwaki K, Otero-de-la-Roza A, Pantelides CC, Parkin S, Pickard CJ, Pilia L, Pivina T, Podeszwa R, Price AJA, Price LS, Price SL, Probert MR, Pulido A, Ramteke GR, Rehman AU, Reutzel-Edens SM, Rogal J, Ross MJ, Rumson AF, Sadiq G, Saeed ZM, Salimi A, Salvalaglio M, Sanders de Almada L, Sasikumar K, Sekharan S, Shang C, Shankland K, Shinohara K, Shi B, Shi X, Skillman AG, Song H, Strasser N, van de Streek J, Sugden IJ, Sun G, Szalewicz K, Tan BI, Tan L, Tarczynski F, Taylor CR, Tkatchenko A, Tom R, Tuckerman ME, Utsumi Y, Vogt-Maranto L, Weatherston J, Wilkinson LJ, Willacy RD, Wojtas L, Woollam GR, Yang Z, Yonemochi E, Yue X, Zeng Q, Zhang Y, Zhou T, Zhou Y, Zubatyuk R, and Cole JC
- Abstract
A seventh blind test of crystal structure prediction was organized by the Cambridge Crystallographic Data Centre featuring seven target systems of varying complexity: a silicon and iodine-containing molecule, a copper coordination complex, a near-rigid molecule, a cocrystal, a polymorphic small agrochemical, a highly flexible polymorphic drug candidate, and a polymorphic morpholine salt. In this first of two parts focusing on structure generation methods, many crystal structure prediction (CSP) methods performed well for the small but flexible agrochemical compound, successfully reproducing the experimentally observed crystal structures, while few groups were successful for the systems of higher complexity. A powder X-ray diffraction (PXRD) assisted exercise demonstrated the use of CSP in successfully determining a crystal structure from a low-quality PXRD pattern. The use of CSP in the prediction of likely cocrystal stoichiometry was also explored, demonstrating multiple possible approaches. Crystallographic disorder emerged as an important theme throughout the test as both a challenge for analysis and a major achievement where two groups blindly predicted the existence of disorder for the first time. Additionally, large-scale comparisons of the sets of predicted crystal structures also showed that some methods yield sets that largely contain the same crystal structures., (open access.)
- Published
- 2024
- Full Text
- View/download PDF
12. Predicting Spin-Dependent Phonon Band Structures of HKUST-1 Using Density Functional Theory and Machine-Learned Interatomic Potentials.
- Author
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Strasser N, Wieser S, and Zojer E
- Subjects
- Density Functional Theory, Phonons, Algorithms, Metal-Organic Frameworks
- Abstract
The present study focuses on the spin-dependent vibrational properties of HKUST-1, a metal-organic framework with potential applications in gas storage and separation. Employing density functional theory (DFT), we explore the consequences of spin couplings in the copper paddle wheels (as the secondary building units of HKUST-1) on the material's vibrational properties. By systematically screening the impact of the spin state on the phonon bands and densities of states in the various frequency regions, we identify asymmetric -COO- stretching vibrations as being most affected by different types of magnetic couplings. Notably, we also show that the DFT-derived insights can be quantitatively reproduced employing suitably parametrized, state-of-the-art machine-learned classical potentials with root-mean-square deviations from the DFT results between 3 cm
-1 and 7 cm-1 . This demonstrates the potential of machine-learned classical force fields for predicting the spin-dependent properties of complex materials, even when explicitly considering spins only for the generation of the reference data used in the force-field parametrization process.- Published
- 2024
- Full Text
- View/download PDF
13. Two-Year Survivorship and Patient-Reported Outcomes of a Prospectively Enrolled Cohort of INFINITY Total Ankle Arthroplasties.
- Author
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Doty J, Murphy GA, Bohay D, Fortin P, Vora A, Strasser N, Friscia D, Newton W, and Gross CE
- Subjects
- Humans, Ankle surgery, Prospective Studies, Survivorship, Treatment Outcome, Canada, Ankle Joint surgery, Reoperation, Patient Reported Outcome Measures, Retrospective Studies, Arthroplasty, Replacement, Ankle adverse effects, Osteoarthritis surgery, Osteoarthritis etiology
- Abstract
Background: The INFINITY total ankle implant is a widely and successfully used option for total ankle arthroplasty. The purpose of this study is to assess the 2-year survivorship, complication rates, patient-reported outcomes, and radiologic findings of prospectively enrolled patients undergoing a fixed-bearing total ankle arthroplasty (TAA). This study sought to determine if factors such as traditional vs patient-specific instrumentation, preoperative degree of arthritis, deformity, or etiology of arthritis impact surgical or clinical outcomes., Methods: A total of 143 prospectively enrolled patients (148 ankles) underwent TAA with a fixed-bearing total ankle implant between 2017 and 2019 at 9 different institutions by 9 different surgeons. A total of 116 completed 2-year follow-up. Patients were stratified by instrumentation used, degree of preoperative deformity, the Canadian Orthopaedic Foot and Ankle Society (COFAS) grading system, and etiology of arthritis. Outcomes used included implant survivorship and adverse events within 2 years of surgery. Additionally, patient-reported outcomes and radiographs were collected at 6-month, 1-year, and 2-year postoperatively. PROMs used included Ankle Osteoarthritis Score (AOS), Patient-Reported Outcomes Measurement Information System (PROMIS) global health score, the Foot and Ankle Outcome Score (FAOS), and patient satisfaction (rated from excellent to poor)., Results: Implant survivorship at 2 years was 97.79%. There were 17 reoperations (11.5%), with 4 of the implants requiring revision (2.7%). Significant improvements in all PROMs were observed among all subgroups at all postoperative time points without significant variation between subgroups. Patients classified as COFAS type 2 arthritis preoperatively demonstrated significantly more improvement in FAOS Total Symptom Score at the 1- and 2-year measurements than COFAS type 3 patients at both time points., Conclusion: Total ankle arthroplasty with a fixed-bearing implant system is a safe and reliable treatment option for patients with end-stage arthritis regardless of degree of deformity or COFAS grading., Level of Evidence: Level II, prospective cohort study., Competing Interests: Ethical ApprovalEthical approval for this study was obtained from Medical University of South Carolina institutional review board Pro00080181. Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: Jesse Doty, MD, reports grants or contracts from any entity; royalties or licenses; consulting fees; and payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Stryker. Donald R. Bohay, MD, FACS, reports consulting fees; and payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing, or educational events from Stryker. G. Andrew Murphy, MD, Paul T. Fortin, MD, and Anand Vora, MD, report support for the present manuscript from Wright Medical. David A. Friscia, MD, reports support for the present manuscript; consulting fees; payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events; and support for attending meetings and/or travel from Stryker. ICMJE forms for all authors are available online.
- Published
- 2024
- Full Text
- View/download PDF
14. The effects of dietary amino acid balance on post-embryonic development in a lubber grasshopper.
- Author
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Hatle J, Clark CR, Agne P, Strasser N, Arcaro J, Kordek EN, Rogers K, Short CA, Sahni Z, Sullivan S, Reams B, and Halleak S
- Subjects
- Male, Animals, Horses, Drosophila melanogaster metabolism, Amino Acids metabolism, Methionine metabolism, Diet, Embryonic Development, Animal Feed, Dietary Proteins metabolism, Vitellogenins metabolism, Grasshoppers metabolism
- Abstract
Effects of dietary protein quality on insect development (not just growth) are unclear. Dietary amino acid blends matching yolk proteins support reproduction and juvenile development in Drosophila melanogaster. We matched amino acids to vitellogenin and tested development of juvenile male lubber grasshoppers, which do not produce vitellogenin. Last instars were fed classic dry diets with amino acids substituted for proteins. Matching amino acids to vitellogenin allowed molting to adulthood, while an unmatched isonitrogenous diet did not. Health on dry diets was poor, so we developed wet diets with agar, horse feed, and amino acids. Juveniles fed these diets matched to vitellogenin developed comparably to juveniles fed lettuce. However, wet diets with amino acids dissimilar to vitellogenin (low-quality) slowed development but maintained size at adulthood. We observed no compensatory feeding on low-quality diets. Theory suggests accumulation of proteins permits development. To detect a threshold, we started last juvenile instars on high-quality diets, then abruptly switched them to low-qualities diets. When switched to the poor-quality diet at 6d, grasshoppers molted at a similar age (∼17d) to grasshoppers continuously on the high-quality diet. Total hemolymph proteins levels were unaffected by the timing of diet switches. Last, methionine is essential but can be noxious at high levels. Diets with low-quality protein except for methionine slowed growth early but did not alter the time or size at molt. Overall, the feeding threshold is solely due to essential amino acids, and low-quality protein diets slowed development but did not affect adult size., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
15. Competing Intramolecular Hydrogen Bond Strengths and Intermolecular Interactions in the 4-Aminobutanol-Water Complex.
- Author
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Hohl JA, Harris MW, Strasser N, Kelterer AM, and Lavrich RJ
- Abstract
We seek to determine the effect of competing intermolecular hydrogen bonds from water on the preferred conformation of 4-aminobutanol (4AB) monomers stabilized by intramolecular hydrogen bonds. Toward this end, the rotational spectrum of the 4-aminobutanol-H
2 O complex was recorded using Fourier transform microwave spectroscopy and fit to the rotational, quadrupole coupling, and centrifugal distortion constants of the Watson S-reduction Hamiltonian. The experimental results are consistent with a 4AB-water complex that preserves the intramolecular hydrogen bond within the 4AB monomer and forms a single intermolecular bond with water acting as a donor. The experimental monomer structure agrees well with the lowest energy conformation calculated at the MP2/6-311++G(d,p) level of theory. Upon complex formation and the introduction of competing intermolecular bonds from water, only small changes in the OH···N intramolecular hydrogen bond and backbone torsional angles of the 4-aminobutanol monomer are observed. Similar small changes were observed for the shorter chain 3-aminopropanol amino alcohol monomer when complexed with water, in contrast to the 2-aminoethanol-H2 O complex. In the latter, a large change in the backbone torsional angle and a breaking of the intramolecular hydrogen bond were observed. Thus, extending the methylene chain results in an increase in the strength of the intramolecular hydrogen bond in unbranched amino alcohols.- Published
- 2018
- Full Text
- View/download PDF
16. Peroneal tendon displacement accompanying intra-articular calcaneal fractures.
- Author
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Toussaint RJ, Lin D, Ehrlichman LK, Ellington JK, Strasser N, and Kwon JY
- Subjects
- Calcaneus diagnostic imaging, Foot Injuries diagnostic imaging, Humans, Intra-Articular Fractures diagnostic imaging, Joint Dislocations diagnostic imaging, Radiography, Retrospective Studies, Tendon Injuries diagnostic imaging, Tendons diagnostic imaging, Tendons surgery, Calcaneus injuries, Foot Injuries complications, Intra-Articular Fractures complications, Joint Dislocations complications, Tendon Injuries complications
- Abstract
Background: Peroneal tendon displacement (subluxation or dislocation) accompanying an intra-articular calcaneal fracture is often undetected and under-treated. The goals of this study were to determine (1) the prevalence of peroneal tendon displacement accompanying intra-articular calcaneal fractures, (2) the association of tendon displacement with fracture classifications, (3) the association of tendon displacement with heel width, and (4) the rate of missed diagnosis of the tendon displacement on radiographs and computed tomography (CT) scans and the resulting treatment rate., Methods: A retrospective radiographic review of all calcaneal fractures presenting at three institutions from June 30, 2006, to June 30, 2011, was performed. CT imaging of 421 intra-articular calcaneal fractures involving the posterior facet was available for review. The prevalence of peroneal tendon displacement was noted and its associations with fracture classification and heel width were evaluated., Results: Peroneal tendon displacement was identified in 118 (28.0%) of the 421 calcaneal fracture cases. The presence of tendon displacement was significantly associated with joint-depression fractures compared with tongue-type fractures (p < 0.001). Only twelve (10.2%) of the 118 cases of peroneal tendon displacement had been identified in the radiology reports. Although sixty-five (55.1%) of the fractures with tendon displacement had been treated with internal fixation, the tendon displacement was treated surgically in only seven (10.8%) of these cases., Conclusions: Analysis of CT images showed a 28% prevalence of peroneal tendon displacement accompanying intra-articular calcaneal fractures. Surgeons and radiologists are encouraged to consider this association.
- Published
- 2014
- Full Text
- View/download PDF
17. A RADIATION PROTECTION SHIELD FOR USE IN THE OPERATING ROOM.
- Author
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STRASSER NF, KRAWZOFF G, LERNER HA, and GILMORE JH
- Subjects
- Humans, Equipment and Supplies, Lead, Operating Rooms, Radiation Protection, Radiology, Radiotherapy, Technology, Radiologic
- Published
- 1964
- Full Text
- View/download PDF
18. Radioactive mercury in the diagnosis of brain tumors.
- Author
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Manfredi RA and Strasser NF
- Subjects
- Adult, Female, Humans, Middle Aged, Brain Neoplasms diagnosis, Mercury, Radionuclide Imaging
- Published
- 1966
19. Use of isotopes for demonstration of lesions in joints and bones as an aid in differential diagnosis.
- Author
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Strasser NF and Thrift CB
- Subjects
- Aged, Arthritis, Rheumatoid diagnosis, Diagnosis, Differential, Gout diagnosis, Hand, Humans, Male, Neoplasm Metastasis, Osteoarthritis diagnosis, Prostatic Neoplasms complications, Serum Albumin, Radio-Iodinated, Strontium Isotopes, Arthritis diagnosis, Lupus Vulgaris diagnosis, Radionuclide Imaging, Scleroderma, Systemic diagnosis, Spinal Neoplasms diagnosis
- Published
- 1968
- Full Text
- View/download PDF
20. Superior mesenteric artery syndrome.
- Author
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HYDE JS, SWARTS CL, NICHOLAS EE, SNEAD CR, and STRASSER NF
- Subjects
- Humans, Duodenal Diseases, Intestinal Obstruction, Mesenteric Arteries, Superior Mesenteric Artery Syndrome
- Published
- 1963
- Full Text
- View/download PDF
21. Excretory urography in pediatric patients with renografin administered intramuscularly.
- Author
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STRASSER NF, LERNER HA, DANCKERS UF, and SNEAD CR
- Subjects
- Child, Humans, Contrast Media, Diatrizoate Meglumine, Kidney Diseases diagnostic imaging, Urogenital System diagnostic imaging, Urography
- Published
- 1962
- Full Text
- View/download PDF
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