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In this paper a lumped parameter electrical model for porous silicon junction field effect transistor (PSJFET) gas sensors is presented and experimentally validated. The PSJFET is an integrated p-channel JFET device modified with a porous silicon layer, the latter acting as sensing element. The model is described by using an analytical closed-form expression, which quantitatively links the sensor current to the analyte concentration in the environment, and validated by using experimental data of PSJFETs exposed to both synthetic air and NO2 with concentration of 300 ppb. Best fitting of experimental data with the proposed model allows one to get quantitative information on the effect of NO2 adsorption/desorption at the PS surface on electrical PS parameters, such as its conductance and surface charge density. [ABSTRACT FROM AUTHOR]

In this work a novel self-powered microneedle-based transdermal biosensor for pain-free high-accuracy real-time measurement of glycaemia in interstitial fluid (ISF) is reported. The proposed transdermal biosensor makes use of an array of silicon-dioxide hollow microneedles that are about one order of magnitude both smaller (borehole down to 4µm) and more densely-packed (up to 1×10(6)needles/cm(2)) than state-of-the-art microneedles used for biosensing so far. This allows self-powered (i.e. pump-free) uptake of ISF to be carried out with high efficacy and reliability in a few seconds (uptake rate up to 1µl/s) by exploiting capillarity in the microneedles. By coupling the microneedles operating under capillary-action with an enzymatic glucose biosensor integrated on the back-side of the needle-chip, glucose measurements are performed with high accuracy (±20% of the actual glucose level for 96% of measures) and reproducibility (coefficient of variation 8.56%) in real-time (30s) over the range 0-630mg/dl, thus significantly improving microneedle-based biosensor performance with respect to the state-of-the-art., (Copyright © 2014 Elsevier B.V. All rights reserved.)