Search

Your search keyword '"Storm, Benjamin S."' showing total 11 results
Start Over Author "Storm, Benjamin S."
11 results on '"Storm, Benjamin S."'

3. Corrigendum: Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies

Author

Marsh, Phillip L., primary, Moore, Ernest E., additional, Moore, Hunter B., additional, Bunch, Connor M., additional, Aboukhaled, Michael, additional, Condon, Shaun M., additional, Al-Fadhl, Mahmoud D., additional, Thomas, Samuel J., additional, Larson, John R., additional, Bower, Charles W., additional, Miller, Craig B., additional, Pearson, Michelle L., additional, Twilling, Christopher L., additional, Reser, David W., additional, Kim, George S., additional, Troyer, Brittany M., additional, Yeager, Doyle, additional, Thomas, Scott G., additional, Srikureja, Daniel P., additional, Patel, Shivani S., additional, Añón, Sofía L., additional, Thomas, Anthony V., additional, Miller, Joseph B., additional, Van Ryn, David E., additional, Pamulapati, Saagar V., additional, Zimmerman, Devin, additional, Wells, Byars, additional, Martin, Peter L., additional, Seder, Christopher W., additional, Aversa, John G., additional, Greene, Ryan B., additional, March, Robert J., additional, Kwaan, Hau C., additional, Fulkerson, Daniel H., additional, Vande Lune, Stefani A., additional, Mollnes, Tom E., additional, Nielsen, Erik W., additional, Storm, Benjamin S., additional, and Walsh, Mark M., additional

Published
2024
Full Text
View/download PDF

4. Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies

Author

Marsh, Phillip L., primary, Moore, Ernest E., additional, Moore, Hunter B., additional, Bunch, Connor M., additional, Aboukhaled, Michael, additional, Condon, Shaun M., additional, Al-Fadhl, Mahmoud D., additional, Thomas, Samuel J., additional, Larson, John R., additional, Bower, Charles W., additional, Miller, Craig B., additional, Pearson, Michelle L., additional, Twilling, Christopher L., additional, Reser, David W., additional, Kim, George S., additional, Troyer, Brittany M., additional, Yeager, Doyle, additional, Thomas, Scott G., additional, Srikureja, Daniel P., additional, Patel, Shivani S., additional, Añón, Sofía L., additional, Thomas, Anthony V., additional, Miller, Joseph B., additional, Van Ryn, David E., additional, Pamulapati, Saagar V., additional, Zimmerman, Devin, additional, Wells, Byars, additional, Martin, Peter L., additional, Seder, Christopher W., additional, Aversa, John G., additional, Greene, Ryan B., additional, March, Robert J., additional, Kwaan, Hau C., additional, Fulkerson, Daniel H., additional, Vande Lune, Stefani A., additional, Mollnes, Tom E., additional, Nielsen, Erik W., additional, Storm, Benjamin S., additional, and Walsh, Mark M., additional

Published
2023
Full Text
View/download PDF

5. Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research-20 years of experience and future perspectives

Author

Mollnes, Tom E., Storm, Benjamin S., Brekke, Ole L., Nilsson, Per H., Lambris, John D., Mollnes, Tom E., Storm, Benjamin S., Brekke, Ole L., Nilsson, Per H., and Lambris, John D.

Abstract

The complex molecular and cellular biological systems that maintain host homeostasis undergo continuous crosstalk. Complement, a component of innate immunity, is one such system. Initially regarded as a system to protect the host from infection, complement has more recently been shown to have numerous other functions, including involvement in embryonic development, tissue modeling, and repair. Furthermore, the complement system plays a major role in the pathophysiology of many diseases. Through interactions with other plasma cascades, including hemostasis, complement activation leads to the broad host-protective response known as thromboinflammation. Most complement research has been limited to reductionistic models of purified components and cells and their interactions in vitro. However, to study the pathophysiology of complement-driven diseases, including the interaction between the complement system and other inflammatory systems, holistic models demonstrating only minimal interference with complement activity are needed. Here we describe two such models; whole blood anticoagulated with either the thrombin inhibitor lepirudin or the fibrin polymerization peptide blocker GPRP, both of which retain complement activity and preserve the ability of complement to be mutually reactive with other inflammatory systems. For instance, to examine the relative roles of C3 and C5 in complement activation, it is possible to compare the effects of the C3 inhibitor compstatin effects to those of inhibitors of C5 and C5aR1. We also discuss how complement is activated by both pathogen-associated molecular patterns, inducing infectious inflammation caused by organisms such as Gram-negative and Gram-positive bacteria, and by sterile damage-associated molecular patterns, including cholesterol crystals and artificial materials used in clinical medicine. When C3 is inhibited, it is important to determine the mechanism by which inflammation is attenuated, i.e., whether the attenuation d

Published
2022
Full Text
View/download PDF

6. Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs

Author

Storm, Benjamin S., primary, Ludviksen, Judith K., additional, Christiansen, Dorte, additional, Fure, Hilde, additional, Pettersen, Kristin, additional, Landsem, Anne, additional, Nilsen, Bent Aksel, additional, Dybwik, Knut, additional, Braaten, Tonje, additional, Nielsen, Erik W., additional, and Mollnes, Tom E., additional

Published
2022
Full Text
View/download PDF

8. Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood

Author

Storm, Benjamin S., primary, Christiansen, Dorte, additional, Fure, Hilde, additional, Ludviksen, Judith K., additional, Lau, Corinna, additional, Lambris, John D., additional, Woodruff, Trent M., additional, Brekke, Ole-Lars, additional, Braaten, Tonje, additional, Nielsen, Erik W., additional, and Mollnes, Tom Eirik, additional

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results