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36 results on '"Stomach cancer -- Development and progression -- Genetic aspects"'

1. Data on Gastric Cancer Detailed by Researchers at Gansu University of Chinese Medicine (Circrtn4 Inhibits the Progression of Gastric Cancer By Sponging Mir-424-5p and Regulating Lats2 Expression)

Subjects
Oncology, Experimental, Gene expression -- Research, Stomach cancer -- Development and progression -- Genetic aspects, RNA -- Health aspects, Cancer -- Research, Health
Abstract

2023 JUL 22 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators discuss new findings in Oncology - Gastric Cancer. According to news [...]

Published
2023

2. New Gastric Cancer Data Has Been Reported by a Researcher at University of Porto (3D Chromatin Architecture Re-Wiring at the CDH3/CDH1 Loci Contributes to E-Cadherin to P-Cadherin Expression Switch in Gastric Cancer)

Subjects
Oncology, Experimental, Gene expression -- Research, Cadherins -- Genetic aspects -- Health aspects, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Research, Health
Abstract

2023 JUN 24 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- A new study on gastric cancer is now available. According to news [...]

Published
2023

3. FAM117B promotes gastric cancer growth and drug resistance by targeting the KEAP1/NRF2 signaling pathway

Author

Zhou, Yunjiang, Chen, Yaxin, Shi, Yongwei, Wu, Leyin, Tan, Yingying, Li, Tao, Chen, Yigang, Xia, Jiazeng, and Hu, Rong

Subjects
Oncology, Experimental, Gene expression -- Research, Drug resistance -- Research, Stomach cancer -- Development and progression -- Genetic aspects, Cellular signal transduction -- Research, Cancer -- Research, Transcription factors -- Health aspects, Health care industry
Abstract

Gastric cancer often shows malignant growth and insensitivity to chemotherapeutic drugs due to the regulation of complex molecular mechanisms, which results in poor prognosis for patients. However, the relevant molecular mechanisms remain unclear. In this study, we reported that family with sequence similarity 117, member B (FAM117B), promoted the growth of gastric cancer cells and reduced the sensitivity of cells to chemotherapeutic drugs. Mechanistically, FAM117B competed with nuclear factor E2-related factor 2 (NRF2) for Kelch-like ECH-associated protein 1 (KEAP1) binding, reduced the ubiquitination degradation of NRF2, and activated the KEAP1/NRF2 signaling pathway. Moreover, FAM117B-induced growth and chemoresistance of gastric cancer cells were NRF2 dependent. We found that FAM117B and NRF2 protein levels were highly expressed in tumor tissues of patients with gastric cancer and their co-overexpression represented an independent factor for poor prognosis. Collectively, our findings reveal that FAM117B is involved in promoting gastric cancer growth and drug resistance, and it could be exploited as a cancer therapeutic target., Introduction Gastric cancer originates from gastric mucosa epithelial cells and is one of the most common malignant tumors of the digestive system. In 2020, there were about 27,600 new cases [...]

Published
2023
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4. Studies from University of Porto Add New Findings in the Area of Gastric Cancer (Syndecan-4 is a maestro of gastric cancer cell invasion and communication that underscores poor survival)

Subjects
Oncology, Experimental, Proteoglycans -- Physiological aspects, Stomach cancer -- Development and progression -- Genetic aspects, Cellular control mechanisms -- Research, Cellular signal transduction -- Research, Cancer cells -- Physiological aspects, Cancer -- Research, Health
Abstract

2023 MAY 27 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on gastric cancer have been presented. According to news reporting [...]

Published
2023

5. Researchers at Fudan University Target Gastric Cancer (System Analysis Based on Lipid-Metabolism-Related Genes Identifies AGT as a Novel Therapy Target for Gastric Cancer with Neoadjuvant Chemotherapy)

Subjects
Renin-angiotensin system -- Physiological aspects -- Health aspects -- Genetic aspects, Stomach cancer -- Development and progression -- Genetic aspects, Lipid metabolism -- Genetic aspects -- Health aspects, Health
Abstract

2023 APR 15 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on gastric cancer have been presented. According to news originating [...]

Published
2023

6. Recent Studies from Xuzhou Medical University Add New Data to Clinical Oncology (Linc00665 Interacts With Bach1 To Activate Wnt1 and Mediates the M2 Polarization of Tumor-associated Macrophages In Gc)

Subjects
Oncology, Experimental, Immune response -- Research, Stomach cancer -- Development and progression -- Genetic aspects, RNA -- Health aspects, Cellular signal transduction -- Research, Macrophages -- Health aspects, Cancer -- Research, Transcription factors -- Health aspects, Health
Abstract

2023 FEB 11 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Clinical Oncology. According to news reporting from [...]

Published
2023

7. Study Findings from First Affiliated Hospital of Bengbu Medical College Broaden Understanding of Gastric Cancer (C5aR1 shapes a non-inflammatory tumor microenvironment and mediates immune evasion in gastric cancer)

Subjects
Immune response -- Health aspects, Stomach cancer -- Development and progression -- Genetic aspects, Health
Abstract

2022 DEC 31 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New study results on gastric cancer have been published. According to news [...]

Published
2022

8. New Apoptosis Study Findings Have Been Reported from Affiliated Hospital of Qingdao University (LncRNA PVT1 Promotes Cell Proliferation, Invasion, and Migration and Inhibits Cell Apoptosis by Phosphorylating YAP)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Phosphorylation -- Health aspects, RNA -- Health aspects, Cancer cells -- Growth -- Genetic aspects -- Health aspects, Company growth, Health
Abstract

2022 JUN 18 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Research findings on apoptosis are discussed in a new report. According to [...]

Published
2022

9. Findings from Jawaharlal Nehru University Has Provided New Data on Gastric Cancer (dna Damage, Cell Cycle Perturbation and Cell Death By Naphthalene Diimide Derivative In Gastric Cancer Cells)

Subjects
Naphthalene -- Health aspects, Cell cycle -- Genetic aspects, Stomach cancer -- Development and progression -- Genetic aspects, DNA damage -- Health aspects, Health
Abstract

2022 JUN 11 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Current study results on Oncology - Gastric Cancer have been published. According [...]

Published
2022

10. New Helicobacter pylori Findings from Mashhad University of Medical Sciences Described (elucidated Tumorigenic Role of Maml1 and Twist1 In Gastric Cancer Is Associated With Helicobacter Pylori Infection & Nbsp;)

Subjects
Oncology, Experimental, Helicobacter infections -- Complications and side effects, Gene expression -- Research, Stomach cancer -- Development and progression -- Genetic aspects, Transcription factors -- Health aspects, Cancer -- Research, Health
Abstract

2022 JUN 4 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Gram-Negative Bacteria - Helicobacter pylori is the subject of [...]

Published
2022

12. New Gastric Cancer Study Findings Reported from National Cancer Center (Functional Loss of P53 Cooperates With the In Vivo Microenvironment To Promote Malignant Progression of Gastric Cancers)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Gene mutation -- Health aspects, Obesity, Cancer research, Technology, Cancer, Physical fitness, Tumor proteins, Editors, Health
Abstract

2019 APR 13 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Oncology - Gastric Cancer. According to news [...]

Published
2019

13. Findings from Linyi People's Hospital Provides New Data on Gastric Cancer (Long noncoding RNA microvascular invasion in hepatocellular carcinoma is an indicator of poor prognosis and a potential therapeutic target in gastric cancer)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Hepatocellular carcinoma -- Development and progression -- Genetic aspects, RNA -- Health aspects, Obesity, Cancer research, Cancer, Physical fitness, Antisense RNA, Carcinoma, Editors, Health
Abstract

2019 APR 6 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Oncology - Gastric Cancer is the subject of a [...]

Published
2019

14. Research Conducted at Shanghai Jiao-Tong University Has Provided New Information about Stomach Cancer (Characterization of Dna Methylation Associated Gene Regulatory Networks During Stomach Cancer Progression)

Subjects
Genetic regulation -- Analysis, Stomach cancer -- Development and progression -- Genetic aspects, Gene silencing -- Analysis, Obesity, Genetic engineering, Cancer genetics, Tumors, DNA, Editors, Cancer research, Methylation, Physical fitness, Genes, Anopheles, Genetic research, Health
Abstract

2019 MAR 2 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Oncology - Stomach Cancer have been presented. According to [...]

Published
2019

15. Findings from National Tsing Hua University Has Provided New Data on Gastric Cancer (KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Transcription factors -- Health aspects, Obesity, Genomics, Cancer, Interleukins, Physical fitness, Epigenetic inheritance, Lysine, Carcinogenesis, Transcription (Genetics), Anopheles, Editors, Health
Abstract

2019 FEB 23 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Investigators publish new report on Oncology - Gastric Cancer. According to news [...]

Published
2019

16. Recent Findings from M.P. Dos Santos and Co-Researchers Yields New Information on Gastritis (Lack of Association between IL-6 Polymorphisms and Haplotypes with Gastric Cancer)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Interleukin-6 -- Genetic aspects, Haplotypes -- Health aspects, Genetic polymorphisms -- Health aspects, Health
Abstract

2018 DEC 29 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Digestive System Diseases and Conditions - Gastritis have been [...]

Published
2018

17. Data on Gastric Cancer Reported by Researchers at Affiliated People's Hospital of Jiangsu University (Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, RNA -- Health aspects, Cancer genetics -- Research, Cancer research, Obesity, Immunologic deficiency syndromes, Cancer, Physical fitness, Antisense RNA, Genes, Anopheles, Editors, Biochemistry, Health
Abstract

2018 DEC 22 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Researchers detail new data in Oncology - Gastric Cancer. According to news [...]

Published
2018

18. Research Findings from Sun Yat-sen University Update Understanding of Cell and Developmental Biology (p53-Induced LINC00893 Regulates RBFOX2 Stability to Suppress Gastric Cancer Progression)

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, RNA -- Health aspects, Biological sciences, Health
Abstract

2022 FEB 1 (NewsRx) -- By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on cell and developmental biology is now available. According to news [...]

Published
2022

19. Research results from Kyushu University, Medical Institute of Bioregulation update knowledge of gastric cancer

Subjects
Oncology, Experimental, Intermediate filament proteins, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Research, Universities and colleges, Health, Kyushu University
Abstract

Fresh data on gastric cancer are presented in the report 'The clinical significance of vimentin-expressing gastric cancer cells in bone marrow.' According to recent research published in the journal Annals [...]

Published
2010

20. Data from Central South University Advance Knowledge in Gastric Cancer

Subjects
Oncology, Experimental, Cancer -- Care and treatment -- Genetic aspects -- Research, Stomach cancer -- Development and progression -- Genetic aspects, Universities and colleges -- China, Biotechnology industry, Health, Science and technology
Abstract

By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Researchers detail new data in Gastric Cancer. According to news originating from Changsha, People's Republic of China, by [...]

Published
2012

21. Research on Gastric Cancer Described by Scientists at First Affiliated Hospital

Subjects
Oncology, Experimental -- Genetic aspects, Methylation, Cancer -- Genetic aspects -- Development and progression -- Research, Stomach cancer -- Development and progression -- Genetic aspects, Scientists, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

Data detailed in 'Role of PCDH10 and its hypermethylation in human gastric cancer' have been presented. 'Epigenetic changes of genomic DNA are involved in the development and progression of many [...]

Published
2012

22. New Findings in Gastric Cancer Described from Ningbo University

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Cancer cells -- Physiological aspects -- Genetic aspects, Cell differentiation -- Physiological aspects -- Genetic aspects, Business, Health, Health care industry
Abstract

In this recently published article, scientists in Zhejiang, People's Republic of China conducted a study 'To investigate the growth effects of 4-phenyl butyric acid (PBA) on human gastric carcinoma cells [...]

Published
2012

23. Leukemia-related protein 16 and colorectal carcinoma

Subjects
Colorectal cancer -- Development and progression -- Genetic aspects, Carcinoma -- Development and progression -- Genetic aspects, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Health
Abstract

Leukemia related protein 16 (LRP16) gene is an important estrogen-responsive gene. LRP16 gene plays an important role in the carcinogenesis and progression of hormone-dependent cancer. LRP16 expression was also reported [...]

Published
2010

24. Research on cancer gene therapy detailed by scientists at Central South University, Department of Pathology

Subjects
Oncology, Experimental -- Development and progression -- Genetic aspects, Genetic research -- Genetic aspects, Gene therapy -- Genetic aspects, Cancer -- Genetic aspects -- Care and treatment -- Development and progression -- Research, Stomach cancer -- Development and progression -- Genetic aspects, Scientists -- Genetic aspects, Bone morphogenetic proteins -- Genetic aspects, Universities and colleges -- Genetic aspects, Biotechnology industry, Health, Science and technology
Abstract

Data detailed in 'TGF-beta promotes invasion and metastasis of gastric cancer cells by increasing fascin1 expression via ERK and JNK signal pathways' have been presented. 'Transforming growth factor-beta (TGF-beta) is [...]

Published
2009

25. Research from Seoul National University, Department of Pharmacy broadens understanding of cancer gene therapy

Subjects
Development and progression, Genetic aspects, Cancer treatment -- Genetic aspects, Stomach cancer -- Development and progression -- Genetic aspects, Universities and colleges -- Genetic aspects, Genetic research -- Genetic aspects, Cancer genetics -- Development and progression -- Genetic aspects, Gene therapy -- Genetic aspects, Cancer -- Development and progression -- Genetic aspects, Cancer research -- Development and progression -- Genetic aspects, Methylation -- Genetic aspects, Pharmacy -- Genetic aspects, Oncology, Experimental -- Development and progression -- Genetic aspects, Cancer -- Care and treatment -- Genetic aspects -- Development and progression -- Research
Abstract

Data detailed in 'Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression' have been presented. 'Mothers against decapentaplegic homologue 4 (SMAD4) is a tumor suppressor gene associated with gastrointestinal [...]

Published
2007

26. Gastric carcinoma susceptibility associated with severe atrophic gastritis

Subjects
Nagoya University, Communicable diseases -- Development and progression -- Genetic aspects, Tumor proteins -- Development and progression -- Genetic aspects, Cell research -- Genetic aspects, Carcinoma -- Development and progression -- Genetic aspects, Gastritis -- Development and progression -- Genetic aspects, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Disease susceptibility -- Development and progression -- Genetic aspects
Abstract

Gastric carcinoma susceptibility could be associated with severe atrophic gastritis. 'Infection with Helicobacter pylori (Hp) has been linked to atrophic gastritis, an inflammatory precursor of non-cardia gastric carcinoma. Mutations in [...]

Published
2006

27. Etiology of gastric cancer discussed

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Diseases -- Causes and theories of causation, Health, Science and technology, Development and progression, Genetic aspects
Abstract

The etiology of gastric cancer was discussed. "Recent advances in understanding of risk factors for gastric cancer have focused attention on genetic polymorphisms in both the human host and in [...]

Published
2005

28. Etiology of gastric cancer discussed

Subjects
Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Diseases -- Causes and theories of causation, Health, Development and progression, Genetic aspects
Abstract

The etiology of gastric cancer was discussed. "Recent advances in understanding of risk factors for gastric cancer have focused attention on genetic polymorphisms in both the human host and in [...]

Published
2005

29. KLF6 gene mutations may encourage gastric cancer progression

Subjects
Gene mutations, Genetic research, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Health, Science and technology, Development and progression, Genetic aspects
Abstract

KLF6 gene mutations may encourage gastric cancer progression. "The KLF6 is a zinc-finger tumor suppressor that is frequently mutated in several human cancers and broadly involved in differentiation and development, [...]

Published
2005

30. KLF6 gene mutations may encourage gastric cancer progression

Subjects
Gene mutations, Genetic research, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Health, Development and progression, Genetic aspects
Abstract

KLF6 gene mutations may encourage gastric cancer progression. "The KLF6 is a zinc-finger tumor suppressor that is frequently mutated in several human cancers and broadly involved in differentiation and development, [...]

Published
2005

31. Epidermal growth factor examined, role of gene mutation in gastric cancer shown

Subjects
Gene mutations, Genetic research, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Epidermal growth factor, Health, Science and technology, Development and progression, Genetic aspects
Abstract

A recently published study from Japan has documented that a single nucleotide polymorphism in the 5' untranslated region of the epidermal growth factor (EGF) gene is associated with occurrence and [...]

Published
2005

32. Helicobacter pylori implicated in gastric cancer progression

Subjects
Communicable diseases -- Development and progression -- Genetic aspects, Chromosome abnormalities -- Development and progression -- Genetic aspects, Helicobacter pylori, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Health, Science and technology, Development and progression, Genetic aspects
Abstract

Helicobacter pylori was implicated as the cause for gastric cancer progression. According to recent research from Wales, "In this series of experiments, a novel protocol was developed whereby gastric cells [...]

Published
2005

33. Epidermal growth factor examined, role of gene mutation in gastric cancer shown

Subjects
Gene mutations, Genetic research, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Epidermal growth factor, Health, Development and progression, Genetic aspects
Abstract

A recently published study from Japan has documented that a single nucleotide polymorphism in the 5' untranslated region of the epidermal growth factor (EGF) gene is associated with occurrence and [...]

Published
2005

34. Helicobacter pylori implicated in gastric cancer progression

Subjects
Development and progression, Genetic aspects, Chromosome abnormalities -- Development and progression -- Genetic aspects, Stomach cancer -- Development and progression -- Genetic aspects, Cancer genetics -- Development and progression -- Genetic aspects, Cancer -- Development and progression -- Genetic aspects, Communicable diseases -- Development and progression -- Genetic aspects, Cytological research -- Genetic aspects, Medical research -- Genetic aspects, Helicobacter pylori -- Genetic aspects, Medicine, Experimental -- Genetic aspects, Cell research -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression
Abstract

Helicobacter pylori was implicated as the cause for gastric cancer progression. According to recent research from Wales, 'In this series of experiments, a novel protocol was developed whereby gastric cells [...]

Published
2005

35. Inactivating mutations of Siah-1 may be factor in gastric cancer development

Subjects
Tumor proteins -- Development and progression -- Genetic aspects, Genetic research, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Health, Science and technology, Development and progression, Genetic aspects
Abstract

According to researchers from South Korea, inactivating mutations of the Siah-1 may be a factor in the development of gastric cancer. W.S. Park and colleagues wrote, "Siah-1 is the mammalian [...]

Published
2005

36. Inactivating mutations of Siah-1 may be factor in gastric cancer development

Subjects
Tumor proteins -- Development and progression -- Genetic aspects, Genetic research, Stomach cancer -- Development and progression -- Genetic aspects, Cancer -- Genetic aspects -- Development and progression, Health, Development and progression, Genetic aspects
Abstract

According to researchers from South Korea, inactivating mutations of the Siah-1 may be a factor in the development of gastric cancer. W.S. Park and colleagues wrote, "Siah-1 is the mammalian [...]

Published
2005

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