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A recent “umbrella” review examined various biomarkers relating to the serotonin system, and concluded there was no consistent evidence implicating serotonin in the pathophysiology of depression. We present reasons for why this conclusion is overstated, including methodological weaknesses in the review process, selective reporting of data, over-simplification, and errors in the interpretation of neuropsychopharmacological findings. We use the examples of tryptophan depletion and serotonergic molecular imaging, the two research areas most relevant to the investigation of serotonin, to illustrate this.

This is the report produced by EGI-ACE Task 7.2 and the EGI Green Computing Task force (established by Task 7.2 with the goal of facilitating awareness of Green issues amongst EGI-ACE partners and overall improvements in Green initiatives). It covers an overview of the activities of the T7.2 working group and Green Task force focusing on the development of detailed objectives, and actions undertaken to fulfill those objectives, along with appendices providing details of the surveying activities and responses. It closes with overall conclusions and recommendations.

In-Person Panel Recording: https://youtu.be/EIRkiurzFSg

TheLong-Term Data Preservation Task Force(LTDP TF) of the EOSC Association has since its establishment worked on mapping the status and further clarification of the meaning of long-term preservation within the EOSC. This work has resulted in anoverview and discussion paperto presents the context, activities and ongoing issues surrounding the EOSC Association Long Term Data Preservation Task Force. The paper describes our approach on preservation in the context of EOSC concerning outcomes, systems, and actions with attention to the vision, roles, finance, and networks needed to deliver preservation for FAIR digital objects in the EOSC. This document is intended to collect community feedback on our approach as well as future recommendations to be considered. We kindly ask the community for feedback on our approach as well as future recommendations to be considered through a short survey: https://ec.europa.eu/eusurvey/runner/TFLTDPsurvey2023

In-Person Poster

In-Person Workshop

Short paper

Current digital preservation systems such as Archivematica and Preservica lack a common and consistent way to describe and execute preservation policies and actions at a technical level. Archivematica’s Format Policy Register (FPR) and Preservica’s Linked Data Registry (LDR) both define what tools and rules to use when doing digital preservation and whilst these two approaches aim to solve similar problems, they are not interoperable. There is no way to share technical information between the two solutions and for users to share their experience on what approaches to use in different contexts and why. This hinders implementation and execution of digital preservation in an interoperable way within the digital preservation community. This paper presents new work by Artefactual, Arkivum, Preservica and Jisc on how Preservation Action Registries (PAR) could be used to capture and share technical best practice for the preservation of digital objects in the form of a corpus of machine-readable recommendations. The registry’s data model defines what tools can be used for different digital object formats, what properties can be extracted or measured and what preservation actions can be taken. The model includes contextual and historical information on the reasons why recommendations are being given. The information is versioned and includes the tool parameters and software environments needed to execute different preservation actions so they are directly ‘executable’ by preservation systems. Our model makes registry content accessible through APIs using a distributed set of registries rather than a single canonical source. In this way, information can be made available from a range of sources including central registries (moderated and curated) or by exchange directly between trusted peer institutions or systems. Preservation systems such as Archivematica and Preservica are able to publish to and consume content from these registries. The work is supported by Jisc as part of the Research Data Shared Service initiative and we believe is the first time that vendors, national service providers and end-users have all come together in this way. The PAR approach should engender greater confidence in digital preservation, provide users with more flexibility and knowledge sharing opportunities, and accelerate the adoption of digital preservation in new sectors.