Introduction: The main aim of this presentation is to introduce project supported by Goce Delcev University, Stip, R. Macedonia, which will be realize during 2015-2016 year. This research study is clinically prospective, cross-sequential, but also partly retrospective because it involves also variables from the past, such as patients’ history data (number of suicidal attempts, stressful life events, etc.). Research objective: This research clinical study is aimed at exploring the differences and similarities between the three groups of depressed patients - respondents: with passive suicidal ideation, with active suicidal ideation, and without suicidal ideation, in respect of certain clinically relevant risk factors for suicide (depression, suicidal ideation, hopelessness, negative life events, suicidal attempts). Special emphasis will be placed on the role of passive suicidal ideation. Sample and psychological instruments: The research will be conducted in two stages. In the first stage (pilot study) the reliability of psychological instruments on a sample from R. Macedonia will be established (Cronbach's alpha coefficient) on a non-clinical sample from Stip and Skopje, aged 19-65. In the second stage, a clinical sample of 200 respondents who met the criteria for major depression was provided in Clinical Hospital in Stip and City Hospital 8th September in Skopje). The variables are operationalized through the set of psychological instruments, which will be adapted for Macedonian population. Based on psychological instruments three groups of depressive patients will be formed that would later be compared: with passive suicidal ideation; with active suicidal ideation; and without suicidal ideation. Expected results: There is a significant association between suicidal ideas (passive and active suicidal ideation), hopelessness, negative life events, suicidal attempts, and depression. There is a significant association between negative life events, suicidal attempts and suicidal ideas. It is expected that the group of active, passive and the group without suicidal ideation will significantly differ among themselves in terms of suicidal ideas, hopelessness, negative life events, depression and suicidal attempts. Suicidal ideas (passive and active suicidal ideation), hopelessness, negative life events, and depression were significant predictors of suicidal attempts. Key words: major depression; active suicidal ideation; passive suicidal ideation; negative life events; suicidal attemps.