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5. Contributors

6. Health-related quality of life in patients given ciltacabtagene autoleucel for relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b–2, open-label study

7. Germline Cancer Susceptibility Gene Testing in Unselected Patients With Colorectal Adenocarcinoma: A Multicenter Prospective Study

8. Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma

9. Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma.

11. Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study

15. Impact of integrated translational research on clinical exome sequencing

16. Genome-wide detection of tandem DNA repeats that are expanded in autism

17. MYC dysregulation in the progression of multiple myeloma

18. Clinical Impact of Pathogenic Germline Variants in Pancreatic Cancer: Results From a Multicenter, Prospective, Universal Genetic Testing Study

20. Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

23. Spectrum and functional validation of PSMB5 mutations in multiple myeloma

24. A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

25. Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma

26. “Direct to Drug” screening as a precision medicine tool in multiple myeloma

27. Mate pair sequencing outperforms fluorescence in situ hybridization in the genomic characterization of multiple myeloma

29. Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients

30. Data from Perspectives on the Risk-Stratified Treatment of Multiple Myeloma

31. Supplementary Table from Perspectives on the Risk-Stratified Treatment of Multiple Myeloma

32. Supplement 2. Next generation sequencing results for first round screen from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

35. Supplement 5. A total of 36 mutations in 19S proteasome subunits out of 895 patients were identified in CoMMpass study. from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

36. Figure S1 from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

37. Supplement 1. sgRNA sequences targeting PSMC1 to C6 from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

38. Supplement 3. sgRNA sequences used for second round screen. from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

41. Supplemental Figure legends from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

42. Supplement 4. Next generation sequencing results for second round screen. from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

43. Table S1: IC50 (nM) for M cells deleted PSMC subunits treated with BTZ from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

47. Supplementary Table S3 from Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas

50. Supplementary Figures S1-S3 from Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas

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