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2,927 results on '"Stevenson, William G."'

4. Clinical Characteristics and Outcomes in Patients With Atrial Fibrillation and Pathogenic TTN Variants

Author

Virk, Zain M., El-Harasis, Majd A., Yoneda, Zachary T., Anderson, Katherine C., Sun, Lili, Quintana, Joseph A., Murphy, Brittany S., Laws, James L., Davogustto, Giovanni E., O’Neill, Matthew J., Varghese, Bibin T., Crawford, Diane M., Williams, Hollie L., Shabani, Mahsima, Pelphrey, Cassady J., Grauherr, Dakota D., Tomasek, Kelsey, Su, Yan Ru, Lancaster, Megan C., Wells, Quinn S., Dendy, Jeffrey M., Saavedra, Pablo, Estrada, Juan C., Richardson, Travis D., Shen, Sharon T., Kanagasundram, Arvindh N., Montgomery, Jay A., Ellis, Christopher R., Crossley, George H., Tandri, Harikrishna, Kannankeril, Prince J., Lubitz, Steven A., Stevenson, William G., Ye, Fei, Ellinor, Patrick T., Stevenson, Lynne W., Roden, Dan M., and Shoemaker, M. Benjamin

Published
2024
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5. Ablation for Atrial Fibrillation in Patients With Rare Pathogenic Variants in Cardiomyopathy and Arrhythmia Genes

Author

El-Harasis, Majd A., Yoneda, Zachary T., Anderson, Katherine C., Ye, Fei, Quintana, Joseph A., Martinez-Parachini, J. Roberto, Jackson, Gregory G., Varghese, Bibin T., Crawford, Diane M., Sun, Lili, Williams, Hollie L., O’Neill, Matthew J., Davogustto, Giovanni E., Laws, James L., Murphy, Brittany S., Tomasek, Kelsey, Su, Yan Ru, McQuillen, Emily, Metz, Emma, Smith, Carly, Stubbs, Doug, Grauherr, Dakota D., Wells, Quinn S., Michaud, Gregory F., Saavedra, Pablo, Carlos Estrada, Juan, Richardson, Travis D., Shen, Sharon T., Kanagasundram, Arvindh N., Montgomery, Jay A., Tandri, Harikrishna, Ellis, Christopher R., Crossley, George H., Kannankeril, Prince J., Stevenson, Lynne W., Stevenson, William G., Lubitz, Steven A., Ellinor, Patrick T., Roden, Dan M., and Shoemaker, M. Benjamin

Published
2024
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6. Substrate Characterization and Outcomes of Ventricular Tachycardia Ablation in Amyloid Cardiomyopathy: A Multicenter Study

Author

Compagnucci, Paolo, Dello Russo, Antonio, Gasperetti, Alessio, Schiavone, Marco, Sehrawat, Ojasav, Hasegawa, Kanae, Mohanty, Sanghamitra, Liang, Jackson J., Kapa, Suraj, La Fazia, Vincenzo Mirco, Bogun, Frank, Stevenson, William G., Tondo, Claudio, Siontis, Konstantinos C., Tandri, Harikrishna, Santangeli, Pasquale, Natale, Andrea, and Casella, Michela

Published
2024
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11. Can Intracardiac Echocardiography Reduce Steam Pops During Half-Normal Saline Irrigated Radiofrequency Ablation?

Author

Hasegawa, Kanae, Yoneda, Zachary T., Martines-Parachini, Jose R., Powers, Edward M., Davogustto, Giovanni E., Hu, Tiffany Y., Tokutake, Kenichi, Kurata, Masaaki, Richardson, Travis D., Montgomery, Jay A., Shen, Sharon, Estrada, Juan C., Saavedra, Pablo J., Emerson, Amy, Walker, Marilyn L., Tandri, Harikrishna, Michaud, Gregory F., Kanagasundram, Arvindh N., and Stevenson, William G.

Published
2024
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20. Abstract 15689: Ablation for Atrial Fibrillation in Patients With Rare Pathogenic Variants in Cardiomyopathy and Arrhythmia Genes

Author

El-Harasis, Majd A, Yoneda, Zachary, Anderson, Katherine, Ye, Fei, Quintana, Joseph, Martinez-Parachini, Jose R, Jackson, Gregory, Varghese, Bibin, Crawford, Diane, Sun, Lili, Williams, Hollie L, OʼNeill, Matthew, Davogustto, Giovanni E, Laws, James L, Murphy, Brittany, Tomasek, Kelsey, Su, Yan Ru, Solem, Emily, Metz, Emma, Smith, Carly, Stubbs, Douglas, Grauherr, Dakota, Wells, Quinn, Michaud, Gregory, saavedra, pablo, Estrada, Juan C, Richardson, Travis, Shen, Sharon, Kanagasundram, Arvindh, Montgomery, Jay A, Tandri, Harikrishna, Ellis, Christopher R, Crossley, George H, Kannankeril, Prince, Stevenson, Lynne W, Stevenson, William G, Lubitz, Steven A, Ellinor, Patrick T, Roden, Dan M, and Shoemaker, Ben B

Published
2023
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25. Predictive Score for Identifying Survival and Recurrence Risk Profiles in Patients Undergoing Ventricular Tachycardia Ablation

Author

Vergara, Pasquale, Tzou, Wendy S, Tung, Roderick, Brombin, Chiara, Nonis, Alessandro, Vaseghi, Marmar, Frankel, David S, Di Biase, Luigi, Tedrow, Usha, Mathuria, Nilesh, Nakahara, Shiro, Tholakanahalli, Venkat, Bunch, T Jared, Weiss, J Peter, Dickfeld, Timm, Lakireddy, Dhanunjaya, Burkhardt, J David, Santangeli, Pasquale, Callans, David, Natale, Andrea, Marchlinski, Francis, Stevenson, William G, Shivkumar, Kalyanam, Sauer, William H, and Della Bella, Paolo

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Heart Disease, Cardiovascular, Good Health and Well Being, Age Factors, Aged, Aged, 80 and over, Catheter Ablation, Cohort Studies, Databases, Factual, Decision Trees, Electrocardiography, Follow-Up Studies, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Predictive Value of Tests, ROC Curve, Recurrence, Retrospective Studies, Risk Assessment, Severity of Illness Index, Sex Factors, Stroke Volume, Survival Analysis, Tachycardia, Ventricular, Time Factors, Treatment Outcome, cardiomyopathies, catheter ablation, mortality, risk assessment, ventricular tachycardia, Cardiorespiratory Medicine and Haematology, Medical Physiology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences, Medical physiology
Abstract

BackgroundSeveral distinct risk factors for arrhythmia recurrence and mortality following ventricular tachycardia (VT) ablation have been described. The effect of concurrent risk factors has not been assessed so far; thus, it is not yet possible to estimate these risks for a patient with several comorbidities. The aim of the study was to identify specific risk groups for mortality and VT recurrence using the Survival Tree (ST) analysis method.MethodsIn 1251 patients 16 demographic, clinical and procedure-related variables were evaluated as potential prognostic factors using ST analysis using a recursive partitioning algorithm that searches for relationships among variables. Survival time and time to VT recurrence in groups derived from ST analysis were compared by a log-rank test. A random forest analysis was then run to extract a variable importance index and internally validate the ST models.ResultsLeft ventricular ejection fraction, implantable cardioverter defibrillator/cardiac resynchronization device, previous ablation were, in hierarchical order, identified by ST analysis as best predictors of VT recurrence, while left ventricular ejection fraction, previous ablation, Electrical storm were identified as best predictors of mortality. Three groups with significantly different survival rates were identified. Among the high-risk group, 65.0% patients were survived and 52.1% patients were free from VT recurrence; within the medium- and low-risk groups, 84.0% and 97.2% patients survived, 72.4% and 88.4% were free from VT recurrence, respectively.ConclusionsOur study is the first to derive and validate a decisional model that provides estimates of VT recurrence and mortality with an effective classification tree. Preprocedure risk stratification could help optimize periprocedural and postprocedural care.

Published
2018

26. Outcomes of Catheter Ablation of Ventricular Tachycardia Based on Etiology in Nonischemic Heart Disease: An International Ventricular Tachycardia Ablation Center Collaborative Study.

Author

Vaseghi, Marmar, Hu, Tiffany Y, Tung, Roderick, Vergara, Pasquale, Frankel, David S, Di Biase, Luigi, Tedrow, Usha B, Gornbein, Jeffrey A, Yu, Ricky, Mathuria, Nilesh, Nakahara, Shiro, Tzou, Wendy S, Sauer, William H, Burkhardt, J David, Tholakanahalli, Venkatakrishna N, Dickfeld, Timm-Michael, Weiss, J Peter, Bunch, T Jared, Reddy, Madhu, Callans, David J, Lakkireddy, Dhanunjaya R, Natale, Andrea, Marchlinski, Francis E, Stevenson, William G, Della Bella, Paolo, and Shivkumar, Kalyanam

Subjects
Humans, Tachycardia, Ventricular, Cardiomyopathies, Catheter Ablation, Treatment Outcome, Retrospective Studies, Adult, Aged, Middle Aged, Female, Male, ablation, arrhythmogenic right ventricular cardiomyopathy, myocarditis, nonischemic, sarcoidosis, valvular, ventricular tachycardia, Rare Diseases, Autoimmune Disease, Cardiovascular, Heart Disease, Clinical Research, Cardiorespiratory Medicine and Haematology, Clinical Sciences
Abstract

ObjectivesThis study sought to characterize ventricular tachycardia (VT) ablation outcomes across nonischemic cardiomyopathy (NICM) etiologies and adjust these outcomes by patient-related comorbidities that could explain differences in arrhythmia recurrence rates.BackgroundOutcomes of catheter ablation of VT in patients with NICM could be related to etiology of NICM.MethodsData from 2,075 patients with structural heart disease referred for catheter ablation of VT from 12 international centers was retrospectively analyzed. Patient characteristics and outcomes were noted for the 6 most common NICM etiologies. Multivariable Cox proportional hazards modeling was used to adjust for potential confounders.ResultsOf 780 NICM patients (57 ± 14 years of age, 18% women, left ventricular ejection fraction 37 ± 13%), underlying prevalence was 66% for dilated idiopathic cardiomyopathy (DICM), 13% for arrhythmogenic right ventricular cardiomyopathy (ARVC), 6% for valvular cardiomyopathy, 6% for myocarditis, 4% for hypertrophic cardiomyopathy, and 3% for sarcoidosis. One-year freedom from VT was 69%, and freedom from VT, heart transplantation, and death was 62%. On unadjusted competing risk analysis, VT ablation in ARVC demonstrated superior VT-free survival (82%) versus DICM (p ≤ 0.01). Valvular cardiomyopathy had the poorest unadjusted VT-free survival, at 47% (p < 0.01). After adjusting for comorbidities, including age, heart failure severity, ejection fraction, prior ablation, and antiarrhythmic medication use, myocarditis, ARVC, and DICM demonstrated similar outcomes, whereas hypertrophic cardiomyopathy, valvular cardiomyopathy, and sarcoidosis had the highest risk of VT recurrence.ConclusionsCatheter ablation of VT in NICM is effective. Etiology of NICM is a significant predictor of outcomes, with ARVC, myocarditis, and DICM having similar but superior outcomes to hypertrophic cardiomyopathy, valvular cardiomyopathy, and sarcoidosis, after adjusting for potential covariates.

Published
2018

29. Ischemic Ventricular Tachycardia

Author

Lugo, Ricardo M., Kanagasundram, Arvindh, Stevenson, William G., Natale, Andrea, editor, Wang, Paul J., editor, Al-Ahmad, Amin, editor, and Estes, N. A. Mark, editor

Published
2020
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34. The precordial R′ wave: A novel discriminator between cardiac sarcoidosis and arrhythmogenic right ventricular cardiomyopathy in patients presenting with ventricular tachycardia

Author

Hoogendoorn, Jarieke C., Venlet, Jeroen, Out, Yannick N.J., Man, Sumche, Kumar, Saurabh, Sramko, Marek, Dechering, Dirk G., Nakajima, Ikutaro, Siontis, Konstantinos C., Watanabe, Masaya, Nakamura, Yoshinori, Tedrow, Usha B., Bogun, Frank, Eckardt, Lars, Peichl, Petr, Stevenson, William G., and Zeppenfeld, Katja

Published
2021
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36. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect

Author

Woodford, Mark R., Baker-Williams, Alexander J., Sager, Rebecca A., Backe, Sarah J., Blanden, Adam R., Hashmi, Fiza, Kancherla, Priyanka, Gori, Alessandro, Loiselle, David R., Castelli, Matteo, Serapian, Stefano A., Colombo, Giorgio, Haystead, Timothy A., Jensen, Sandra M., Stetler-Stevenson, William G., Loh, Stewart N., Schmidt, Laura S., Linehan, W. Marston, Bah, Alaji, Bourboulia, Dimitra, Bratslavsky, Gennady, and Mollapour, Mehdi

Published
2021
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40. Sarcoid Ventricular Tachycardia

Author

Lugo, Ricardo M., Kanagasundram, Arvindh, Stevenson, William G., Natale, Andrea, editor, Wang, Paul J., editor, Al-Ahmad, Amin, editor, and Estes, N. A. Mark, editor

Published
2020
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41. Retrograde coronary venous ethanol ablation for ventricular tachycardia in a patient with inaccessible substrate due to previous surgery.

Author

Weinand, Nicholas, Thind, Munveer, Pomerantz, Brian, Hu, Tiffany, Stevenson, William G., and Richardson, Travis

Subjects
CORONARY artery surgery, ABLATION techniques, ETHANOL, TREATMENT effectiveness, RADIO frequency therapy, VENTRICULAR tachycardia, CORONARY arteries, CATHETER ablation
Abstract

Introduction: Catheter‐based radiofrequency (RF) ablation is generally regarded as the standard approach for patients with ventricular tachycardia (VT) refractory to antiarrhythmic drug therapy and may be considered as a first‐line approach when there is a preference to avoid these agents. Patients with a history of cardiac surgery may have VT substrate inaccessible to catheter ablation due to intervening prosthetic materials or scar. Methods and Results: This article describes a 55‐year‐old patient with a history of surgically repaired subvalvular aortic stenosis and subsequent valve‐sparing root replacement who presented with sustained VT. After RF ablation failed due to VT substrate "guarded" by graft material, retrograde coronary venous ethanol ablation (RCVEA) was employed to successfully treat the clinical VT. Conclusion: RCVEA ablation can be useful for treating VT when conventional ablation is limited by inaccessible substrate due to prior cardiac surgery. [ABSTRACT FROM AUTHOR]

Published
2024
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44. 2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias

Author

Cronin, Edmond M., Bogun, Frank M., Maury, Philippe, Peichl, Petr, Chen, Minglong, Namboodiri, Narayanan, Aguinaga, Luis, Leite, Luiz Roberto, Al-Khatib, Sana M., Anter, Elad, Berruezo, Antonio, Callans, David J., Chung, Mina K., Cuculich, Phillip, d’Avila, Andre, Deal, Barbara J., Della Bella, Paolo, Deneke, Thomas, Dickfeld, Timm-Michael, Hadid, Claudio, Haqqani, Haris M., Kay, G. Neal, Latchamsetty, Rakesh, Marchlinski, Francis, Miller, John M., Nogami, Akihiko, Patel, Akash R., Pathak, Rajeev Kumar, Saenz Morales, Luis C., Santangeli, Pasquale, Sapp, John L., Jr., Sarkozy, Andrea, Soejima, Kyoko, Stevenson, William G., Tedrow, Usha B., Tzou, Wendy S., Varma, Niraj, and Zeppenfeld, Katja

Published
2020
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45. Intramural needle ablation or repeated standard ablation in patients referred for repeat ablation of scar‐related ventricular tachycardia

Author

Kurata, Masaaki, primary, Batnyam, Uyanga, additional, Tedrow, Usha B., additional, Richardson, Travis D., additional, Kanagasundram, Arvindh N., additional, Hasegawa, Kanae, additional, Uetake, Shunsuke, additional, Manuelian, Deborah, additional, Pellegrini, Christine, additional, and Stevenson, William G., additional

Published
2024
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46. Safety of Ventricular Arrhythmia Radiofrequency Ablation with Half-Normal Saline Irrigation

Author

Hasegawa, Kanae, primary, Yoneda, Zachary T, additional, Powers, Edward M, additional, Tokutake, Kenichi, additional, Kurata, Masaaki, additional, Richardson, Travis D, additional, Montgomery, Jay A, additional, Shen, Sharon, additional, Estrada, Juan C, additional, Saavedra, Pablo J, additional, Emerson, Amy, additional, Walker, Marilyn L, additional, Tandri, Harikrishna, additional, Michaud, Gregory F, additional, Kanagasundram, Arvindh N, additional, and Stevenson, William G, additional

Published
2024
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49. Prognostic Impact of the Timing of Recurrence of Infarct-Related Ventricular Tachycardia After Catheter Ablation

Author

Siontis, Konstantinos C, Kim, Hyungjin Myra, Stevenson, William G, Fujii, Akira, Bella, Paolo Della, Vergara, Pasquale, Shivkumar, Kalyanam, Tung, Roderick, Do, Duc H, Daoud, Emile G, Okabe, Toshimasa, Zeppenfeld, Katja, Riva Silva, Marta de, Hindricks, Gerhard, Arya, Arash, Weber, Alexander, Kuck, Karl-Heinz, Metzner, Andreas, Mathew, Shibu, Riedl, Johannes, Yokokawa, Miki, Jongnarangsin, Krit, Latchamsetty, Rakesh, Morady, Fred, and Bogun, Frank M

Subjects
Heart Disease, Cardiovascular, Aged, Catheter Ablation, Female, Heart Transplantation, Humans, Male, Myocardial Infarction, Prognosis, Recurrence, Tachycardia, Ventricular, Time Factors, Treatment Outcome, catheter ablation, myocardial infarction, prognosis, recurrence, ventricular tachycardia, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Medical Physiology, Cardiovascular System & Hematology
Abstract

Recurrence of ventricular tachycardia (VT) after ablation in patients with previous myocardial infarction is associated with adverse prognosis. However, the impact of the timing of VT recurrence on outcomes is unclear. We analyzed data from a multicenter collaborative database of patients who underwent catheter ablation for infarct-related VT. Multivariable Cox regression analyses investigated the effect of the timing of VT recurrence on the composite outcome of death or heart transplantation using VT recurrence as a time-varying covariate. A total of 1412 patients were included (92% men; age: 66.7±10.7 years), and 605 patients (42.8%) had a recurrence after median 116 days (188 [31.1%] within 1 month, 239 [39.5%] between 1 and 12 months, and 178 [29.4%] after 12 months). At median follow-up of 670 days, 375 patients (26.6%) experienced death or heart transplantation. The median time from recurrence to death or heart transplantation was 65 and 198.5 days in patients with recurrence ≤30 days and >30 days post ablation, respectively. The adjusted hazard ratio (95% confidence interval) for the effect of VT recurrence occurring immediately post ablation on death or heart transplantation was 3.45 (2.33-5.11) in reference to no recurrence. However, the magnitude of this effect decreased statistically significantly (P

Published
2016

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