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Purpose: To examine the effect of fast- versus slow-speed eccentric-muscle-action resistance training on lower-body strength, vertical jump height, sprint speed, and change-of-direction performance in elite soccer players during a competitive season. Methods: Twenty-two elite soccer players, from a single team, were randomly assigned to groups that undertook either 1- (fast speed) or 4-second (slow speed) eccentric resistance training during the in-season period. A 5-week program was conducted during an elite top-division European League soccer season. Performance measures including predicted 1-repetition-maximum back squat, countermovement jump, 20-m sprint, and change of direction were tested before and after the intervention period. Total match and training running distance and muscle soreness were also recorded during each week of the intervention. Results: An analysis of covariance showed significant group effects (P = .01) for countermovement jump with a greater jump height in the 1-second fast-speed group postintervention (95% CI, 1.1–6.9 cm). Despite an overall increase in 1-repetition maximum pretraining to posttraining (95% CI, 10.0–15.3 kg, effect size 0.69), there were no significant differences (P > .05) between groups after the intervention. Similarly, there were no differences between groups for change of direction, 20-m sprint, or muscle soreness. Conclusion: Faster eccentric muscle actions may be superior for increasing movements in elite soccer players in-season.

This study examined the effect of aerobic exercise with and without blood flow restriction (BFR) on exercise-induced hypoalgesia and endogenous opioid and endocannabinoid systems. In a randomized crossover design, pain-free individuals performed 20 min of cycling in four experimental trials: 1) low-intensity aerobic exercise (LI-AE) at 40% V̇o2max; 2) LI-AE with low-pressure BFR (BFR40); 3) LI-AE with high-pressure BFR (BFR80); and 4) high-intensity aerobic exercise (HI-AE) at 70% V̇o2max. Pressure pain thresholds (PPTs) were assessed before and 5 min postexercise. Circulating concentrations of beta-endorphin and 2-arachidonoylglycerol were assessed before and 10 min postexercise. In the exercising legs, postexercise PPTs were increased following BFR40 and BFR80 compared with LI-AE (23–32% vs. 1–2% increase, respectively). The increase in PPTs was comparable to HI-AE (17–20% increase) with BFR40 and greater with BFR80 (30–32% increase). Both BFR80 and HI-AE increased PPTs in remote areas of the body (increase of 26–28% vs. 19–21%, respectively). Postexercise circulating beta-endorphin concentration was increased following BFR40 (11%) and HI-AE (14%), with the greatest change observed following BFR80 (29%). Postexercise circulating 2-arachidonoylglycerol concentration was increased following BFR40 (22%) and BFR80 (20%), with the greatest change observed following HI-AE (57%). Addition of BFR to LI-AE can trigger both local and systemic hypoalgesia that is not observed follow LI-AE alone and activate endogenous opioid and endocannabinoid systems of pain inhibition. Compared with HI-AE, local and systemic hypoalgesia following LI-AE with high-pressure BFR is greater and comparable, respectively. LI-AE with BFR may help pain management in load-compromised individuals.\ud \ud NEW & NOTEWORTHY We have shown that performing blood flow restriction (BFR) during low-intensity aerobic exercise can trigger local and systemic hypoalgesia, which is not typically observed with this intensity of exercise. High-pressure BFR triggers greater and comparable hypoalgesia than high-intensity aerobic exercise in the exercising limbs and remote areas of the body, respectively. Performing BFR during low-intensity aerobic exercise activates the opioid and endocannabinoid systems, providing novel insight into potential mechanisms of hypoalgesia with BFR exercise

Longitudinal changes in anthropometric and physical performance characteristics of International female rugby union players were evaluated across 5-seasons, according to field position. Sixty-eight international female rugby union players from a top 2 ranked international team, undertook anthropometric and physical performance measurements across five seasons. Anthropometric and physical performance changes occurred, with skinfolds decreasing between 2015 and 2017 and body mass increasing between 2017 and 2019. Single-leg isometric squat (SL ISO), 0-10 m momentum (0-10 Mom) and 20-30 m momentum (20-30Mom) were higher in 2018 and 2019 than all years. Front-row players were characterised by greater SL ISO and 1-RM bench press than inside and outside backs, with higher skinfolds and lower endurance levels than all positions. Between 2017 and 2019, front-row players had larger decreases and increases in endurance and one repetition maximum (1-RM) bench press, respectively, compared to all other positions. Forwards had the highest 0-10Mom and 20-30Mom, and scrum-half the lowest, while outside backs had faster 0-10, 30-40, and 40 m (TT40 m) times, and greater peak velocity (Vmax) compared to forward positions. These longitudinal findings show that physical performance has increased, with anthropometric and performance characteristics becoming more distinctive between positions, among elite female rugby union players.

The aim of this investigation was to determine if acute or repeated applications of ischemic preconditioning (IPC) could enhance the recovery process, following exercise induced muscle damage (EIMD).Randomized control trial.Twenty-three healthy males were familiarised with the muscle damaging protocol (five sets of 20 drop jumps from a 0.6 m box) and randomly allocated to one of three groups: SHAM (3 × 5 min at 20 mmHg), Acute IPC (3 × 5 min at 220 mmHg) and Repeated IPC (3 days x 3 × 5 min at 220 mmHg). The indices of muscle damage measured included creatine kinase concentration ([CK]), thigh swelling, delayed onset muscle soreness, counter movement jumps (CMJ) and maximal voluntary isometric contraction (MVIC).Both acute and repeated IPC improved recovery in MVIC versus SHAM. Repeated IPC led to a faster MVIC recovery at 48 h (101.5%) relative to acute IPC (92.6%) and SHAM (84.4%) (P 0.05). Less swelling was found for both acute and repeated IPC vs. SHAM (P 0.05) but no group effects were found for CMJ, soreness or [CK] responses (P 0.05).Taken together, repeated IPC can enhance recovery time of MVIC more than an acute application, and both reduce swelling following EIMD, relative to a SHAM condition.

Lovegrove, S, Hughes, L, Mansfield, S, Read, P, Price, P, and Patterson, SD. Repetitions in reserve is a reliable tool for prescribing resistance training load. J Strength Cond Res 36(10): 2696-2700, 2022-This study investigated the reliability of repetitions in reserve (RIR) as a method for prescribing resistance training load for the deadlift and bench press exercises. Fifteen novice trained men (age: 17.3 ± 0.9 years, height: 176.0 ± 8.8 cm, body mass: 71.3 ± 10.7 kg) were assessed for 1 repetition maximum (1RM) for deadlift (118.1 ± 27.3 kg) and bench press (58.2 ± 18.6 kg). Subsequently, they completed 3 identical sessions (one familiarization session and 2 testing sessions) comprising sets of 3, 5, and 8 repetitions. For each repetition scheme, the load was progressively increased in successive sets until subjects felt they reached 1-RIR at the end of the set. Test-retest reliability of load prescription between the 2 testing sessions was determined using intraclass correlation coefficient (ICC) and coefficient of variation (CV). A 2-way analysis of variance with repeated measures was used for each exercise to assess differences in the load corresponding to 1-RIR within each repetition scheme. All test-retest comparisons demonstrated a high level of reliability (deadlift: ICC = 0.95-0.99, CV = 2.7-5.7% and bench press: ICC = 0.97-0.99, CV = 3.8-6.2%). Although there were no differences between time points, there was a difference for load corresponding to 1-RIR across the 3 repetition schemes (deadlift: 88.2, 84.3, and 79.2% 1RM; bench press: 93.0, 87.3, and 79.6% 1RM for the 3-, 5-, and 8-repetition sets, respectively). These results suggest that RIR is a reliable tool for load prescription in a young novice population. Furthermore, the between-repetition scheme differences highlight that practitioners can effectively manipulate load and volume (repetitions in a set) throughout a training program to target specific resistance training adaptations.

Uddin, N, Jeffries, O, Read, P, Howe, L, Patterson, S, and Waldron, M. Physiological responses to linear and nonlinear soccer-specific match simulations and their effects on lower-limb muscle fatigue. J Strength Cond Res 34(11): 3232-3240, 2020-The aims of this study were to: (a) investigate the effects of linear and nonlinear soccer simulations on lower-limb muscle function and physiological responses and (b) evaluate the relationship between match-running demands and changes in lower-limb muscle function. In a repeated-measures cross-over design, 8 participants completed either a linear or nonlinear adapted Loughborough Intermittent Shuttle Test (LIST) on 2 occasions. The movement of players was tracked with a global positioning system, while lower-limb muscle function tests and physiological measurements were performed before and every 15 minutes during the simulation. There were no differences in distance covered, yet high-speed running (p = 0.007), accelerations (p = 0.008), and decelerations (p = 0.015) were higher in the linear LIST. Mean heart rate (p = 0.001) and ratings of perceived exertion (p = 0.013) were higher in the nonlinear LIST. Peak landing forces (p = 0.017) and jump height (p = 0.001) were reduced between baseline and 90 minutes but were not different between conditions. Changes in peak landing forces from baseline to half-time (r = -0.57, n = 16, p = 0.022) and full-time (r = -0.58, n = 16, p = 0.019) were related to high-speed running. Hamstring force was unaffected by time (p = 0.448) but was reduced in the linear LIST (p = 0.044). Protocols posing different external and internal demands elicited similar levels of fatigue across simulations. Hamstring function was not an effective indicator of fatigue, but our results highlight the greater demands placed on this muscle group when higher-speed running is performed.

\ud Objective – There is a high incidence of concussion and frequent utilization of Rapid Weight Loss (RWL) methods among combat sport athletes, yet the apparent similarity in symptoms experienced as a result of a concussion or RWL has not been investigated. This study surveyed combat sports athletes to investigate the differences in symptom-onset and recovery between combat sports and evaluated the relationships between concussion and RWL symptoms.\ud Design – Cross-Sectional Study\ud Setting – Data were collected via an online survey.\ud Participants – 132 (male 115, female 17) combat sport athletes.\ud Interventions – Modified Sport Concussion Assessment Tool (SCAT) symptom checklist and weight-cutting questionnaire.\ud Main Outcome Measures – Survey items included combat sport discipline, weight loss, and medical history, weight-cutting questionnaire, and concussion & weight-cutting symptom checklists.\ud Results – Strong associations (rs = 0.6 – 0.7, p < 0.05) were observed between concussion and RWL symptoms. The most frequently reported symptom resolution times were 24 - 48 h for a weight-cut (WC; 59%) and 3 - 5 days for a concussion (43%), with 60 - 70% of athletes reporting a deterioration and lengthening of concussion symptoms when undergoing a WC. The majority of athletes (65%) also reported at least one WC in their career to ‘not go according to plan’, resulting in a lack of energy (83%) and strength/power (70%).\ud Conclusions – RWL and concussion symptoms are strongly associated, with the majority of athletes reporting a deterioration of concussion symptoms during a WC. The results indicate that concussion symptoms should be monitored alongside hydration status to avoid any compound effects of prior RWL on the interpretation of concussion assessments and to avoid potential misdiagnoses among combat athletes.

INTRODUCTION:During spaceflight missions, astronauts work in an extreme environment with several hazards to physical health and performance. Exposure to microgravity results in remarkable deconditioning of several physiological systems, leading to impaired physical condition and human performance, posing a major risk to overall mission success and crew safety. Physical exercise is the cornerstone of strategies to mitigate physical deconditioning during spaceflight. Decades of research have enabled development of more optimal exercise strategies and equipment onboard the International Space Station. However, the effects of microgravity cannot be completely ameliorated with current exercise countermeasures. Moreover, future spaceflight missions deeper into space require a new generation of spacecraft, which will place yet more constraints on the use of exercise by limiting the amount, size, and weight of exercise equipment and the time available for exercise. Space agencies are exploring ways to optimize exercise countermeasures for spaceflight, specifically exercise strategies that are more efficient, require less equipment, and are less time-consuming. Blood flow restriction exercise is a low intensity exercise strategy that requires minimal equipment and can elicit positive training benefits across multiple physiological systems. This method of exercise training has potential as a strategy to optimize exercise countermeasures during spaceflight and reconditioning in terrestrial and partial gravity environments. The possible applications of blood flow restriction exercise during spaceflight are discussed herein.Hughes L, Hackney KJ, Patterson SD.Optimization of exercise countermeasures to spaceflight using blood flow restriction. Aerosp Med Hum Perform. 2021; 93(1):32–45.

Purpose This study investigated the effects of a 10-day heat acclimation (HA) programme on the time course of changes in thermoneutral maximal oxygen uptake ($$\dot{V}$$ V ˙ O2max) during and up to 10 days post-HA. Methods Twenty-two male cyclists were assigned to a HA or control (Con) training group following baseline ramp tests of thermoneutral $$\dot{V}$$ V ˙ O2max. Ten days of fixed-intensity (50% baseline $$\dot{V}$$ V ˙ O2max) indoor cycling was performed in either ~ 38.0 °C (HA) or ~ 20 °C (Con). $$\dot{V}$$ V ˙ O2max was re-tested on HA days 5, 10 and post-HA days 1, 2, 3, 4, 5 and 10. Results $$\dot{V}$$ V ˙ O2max initially declined across time in both groups during training (P P $$\dot{V}$$ V ˙ O2max was higher than control by post-HA day 4 in the HA group (P = 0.046). Conclusions The non-linear time course of $$\dot{V}$$ V ˙ O2max adaptation suggests that post-testing should be performed 96-h post-training to identify the maximal change for most individuals. In preparation for training or testing, athletes can augment their aerobic power in thermoneutral environments by performing 10 days HA, but the full effects will manifest at varying stages of the post-HA period.

Ischaemic preconditioning (IPC) has emerged as a potential non-invasive ergogenic aid to enhance exercise performance. Repeated application of IPC has demonstrated clinical efficacy, therefore our aims were to investigate its effect on endurance cycling performance and muscle efficiency. Twenty participants undertook 7-d repeated bilateral lower limb occlusion (4 x 5-min) of IPC (220 mmHg) or sham (20 mmHg). Prior to and 72-h following the intervention, participants performed submaximal cycling at 70, 80 and 90% of ventilatory threshold (VT) followed by an incremental exercise test. IPC had no effect on

Ischemic preconditioning (IPC) has been suggested as a potential ergogenic aid to improve exercise performance, although controversial findings exist. The controversies may be explained by several factors, including the mode of exercise, the ratio between the magnitude of improvement, or the error of measurement and physiological meaning. However, a relevant aspect has been lacking in the literature: the interpretation of the findings considering statistical tests and adequate effect size (ES) according to the fitness level of individuals. Thus, we performed a systematic review with meta-analysis to update the effects of IPC on exercise performance and physiological responses, using traditional statistics (P values), ES, and smallest worth change (SWC) approach contextualizing the IPC application to applied Sports and Exercise performance. Forty-five studies met the inclusion criteria. Overall, the results show that IPC has a minimal or nonsignificant effect on performance considering the fitness level of the individuals, using statistical approaches (i.e., tests with P value, ES, and SWC). Therefore, IPC procedures should be revised and refined in future studies to evaluate if IPC promotes positive effects on performance in a real-world scenario with more consistent interpretation.

The purpose of this study was to determine the primary cues regulating perceived effort and exercise performance using a fixed-RPE protocol in severe and moderate hypoxia. Eight male participants (26 ± 6 years, 76.3 ± 8.6 kg, 178.5 ± 3.6 cm, 51.4 ± 8.0 mL kg− 1 min− 1 $$\dot {V}$$ O2max) completed three exercise trials in environmental conditions of severe hypoxia (FIO2 0.114), moderate hypoxia (FIO2 0.152), and normoxia (FIO2 0.202). They were instructed to continually adjust their power output to maintain a perceived effort (RPE) of 16, exercising until power output declined to 80% of the peak 30-s power output achieved. Exercise time was reduced (severe hypoxia 428 ± 210 s; moderate hypoxia 1044 ± 384 s; normoxia 1550 ± 590 s) according to a reduction in FIO2 (P 0.05). Minute ventilation increased at a faster rate according to a decrease in FIO2 (severe hypoxia 27.6 ± 6.6; moderate hypoxia 21.8 ± 3.9; normoxia 17.3 ± 3.9 L min− 1). Moderate-to-strong correlations were identified between breathing frequency (r = − 0.718, P

Muscle wasting is implicated in the pathogenesis of intensive care unit acquired weakness (ICU-AW), affecting 40% of patients and causing long-term physical disability. A repetitive vascular occlusion stimulus (RVOS) limits muscle atrophy in healthy and orthopaedic subjects, thus, we explored its application to ICU patients. Adult multi-organ failure patients received standard care +/− twice daily RVOS {4 cycles of 5 min tourniquet inflation to 50 mmHg supra-systolic blood pressure, and 5 min complete deflation} for 10 days. Serious adverse events (SAEs), tolerability, feasibility, acceptability, and exploratory outcomes of the rectus femoris cross-sectional area (RFCSA), echogenicity, clinical outcomes, and blood biomarkers were assessed. Only 12 of the intended 32 participants were recruited. RVOS sessions (76.1%) were delivered to five participants and two could not tolerate it. No SAEs occurred; 75% of participants and 82% of clinical staff strongly agreed or agreed that RVOS is an acceptable treatment. RFCSA fell significantly and echogenicity increased in controls (n = 5) and intervention subjects (n = 4). The intervention group was associated with less frequent acute kidney injury (AKI), a greater decrease in the total sequential organ failure assessment score (SOFA) score, and increased insulin-like growth factor-1 (IGF-1), and reduced syndecan-1, interleukin-4 (IL-4) and Tumor necrosis factor receptor type II (TNF-RII) levels. RVOS application appears safe and acceptable, but protocol modifications are required to improve tolerability and recruitment. There were signals of possible clinical benefit relating to RVOS application.

Explosive actions are integral to soccer performance and highly influenced by the ability to generate maximal power. The purpose of this study was to investigate the relationship between force-velocity profile, jump performance, acceleration and maximal sprint speed in elite female soccer players. Thirty-nine international female soccer players (24.3±4.7 years) performed 40-m sprints, maximal countermovement jumps and five loaded squat jumps at increasing loads to determine individual force-velocity profiles. Theoretical maximal velocity, theoretical maximal force, maximal power output, one repetition maximal back squat and one repetition maximal back squat relative to body mass were determined using the force-velocity profile. Counter movement jump, squat jump and maximal power output demonstrated moderate to large correlation with acceleration and maximal sprint speed (r=− 0.32 to −0.44 and −0.32 to −0.67 respectively, p0.05). Vertical force-velocity profiling and maximal strength can provide valuable insight into the neuromuscular qualities of an athlete to individualize training, but the ability to produce force, maximal power, and further transference into sprint performance, must be central to program design.

Performing exercise with compression of the limb vasculature was founded in Japan during the 1990s as kaatsu training, meaning ‘added pressure.’ The adaptations that underpin these various applications of blood flow restriction (BFR) arise from significant alteration to local tissue physiology during BFR. The application of BFR has evolved rapidly over the past decade. Research shows that the most significant aspect of BFR application that relates to both the effectiveness and safety of the BFR stimulus is the pressure applied and type of cuff used. The nature of BFR exercise has elicited several concerns over the safety of this modality, which have been explored within research. Safety concerns include possible effects on the cardiovascular system and muscle damage. The most documented aspect of BFR exercise is the effect on muscular adaptations to training. It is well understood that muscle hypertrophy and strength adaptations to BFR training are significantly greater than those achieved with exercise at an equivalent intensity without BFR.

IntroductionChronic low back pain (CLBP) is a leading cause of disability in the UK Military. Pain and psychological comorbidities have been reported to influence the rating of perceived exertion (RPE). Exercise rehabilitation can be monitored using RPE; however, the accuracy of RPE in inpatient CLBP rehabilitation is unknown.MethodsA prospective cohort correlation study of 40 UK Military inpatients with CLBP was completed. Disability (ODI), kinesiophobia (TSK), anxiety (GAD-7) and depression (PHQ-9) were subjectively reported at the beginning and end of a 3 week intervention. Pain (VAS) and HR were recorded in the first aerobic exercise (AE) session (T1) and the final aerobic exercise session (T2). RPE was reported for each AE session.ResultsAt T1, a positive correlation was observed between RPE accuracy (−7.2±20.9), and pre-exercise pain (2.7 mm ±1.6 mm) (p>0.001) and ODI (31.0±16.9) (p>0.05), and a negative relationship between RPE accuracy and average HR (135 bpm ±22 bpm) (p>0.001) was observed. At T2, there was no significant correlation between RPE accuracy (−4.4±22.6) and pre-exercise pain (2.8 mm ±1.6 mm) or ODI (34.0±16.5) (p>0.05). The strong negative relationship between RPE accuracy and average HR (137 bpm ±20 bpm) remained at T2. Improved RPE accuracy over the 3-week rehabilitation programme was correlated to the change in average HR (r=−0.314, pConclusionsComorbidities may negatively affect RPE accuracy in CLBP, but the magnitude of the influence reduces over intensive rehabilitation.

Objectives This study aimed to evaluate changes in rugby union physical match characteristics across five seasons of International female competition, according to position and opposition quality. Design & methods Global positional systems and performance analysis data from 78 female rugby union players (minimum of five international appearances) were analysed between 2015 and 2019. Mixed-linear-modelling was used to investigate the effects of season, opposition and position during 969 individual match performances from 53 International matches. Results Running demands increased between 2015 and 2017 (World Cup year) and plateaued thereafter, except for sprints among the outside backs, which declined between 2017 and 2019, and accelerations and decelerations >3 m s2 which increased between 2017 and 2019. Collisions were higher in forwards than backs, and highest against stronger opposition. Running demands were greater against weaker opposition, but the ‘most intense periods’ of running were greater against stronger opposition in 2017. Conclusions Match demands increased between 2015 and the 2017 World Cup year, which was underpinned by increased sprinting and greater running during maximum intensity periods against top 5 opposition. The increase in accelerations and decelerations in the latter years, alongside the maintenance of average running demands and collision counts, is consistent with the reported continuous playing style of female rugby, thus placing specific demands on players and requiring tailored training methods. Some positions (Forwards and Scrum-halves) appear to be important for this adopted style, demonstrating concomitantly high relative collision and running intensities.

Context: Neuromuscular electrical stimulation (NMES) combined with blood flow restriction (BFR) has been shown to improve muscular strength and size better than NMES alone. However, previous studies used varied methodologies not recommended by previous NMES or BFR research. Objective: The present study investigated the acute effects of NMES combined with varying degrees of BFR using research-recommended procedures to enhance understanding and the clinical applicability of this combination. Design: Randomized crossover. Setting: Physiology laboratory. Participants: A total of 20 healthy adults (age 27 [4] y; height 177 [8] cm; body mass 77 [13] kg). Interventions: Six sessions separated by at least 7 days. The first 2 visits served as familiarization, with the experimental conditions performed in the final 4 sessions: NMES alone, NMES 40% BFR, NMES 60% BFR, and NMES 80% BFR. Main Outcome Measures: Maximal voluntary isometric contraction, muscle thickness, blood pressure, heart rate, rating of perceived exertion, and pain were all recorded before and after each condition. Results: The NMES 80% BFR caused greater maximal voluntary isometric contraction decline than any other condition (−38.9 [22.3] N·m, P P P Conclusion: The NMES combined with 80% BFR caused greater acute force decrement than the other conditions. However, greater perceptual ratings of pain and ratings of perceived exertion were observed with NMES 80% BFR. These acute observations must be investigated during chronic interventions to corroborate any relationship to changes in muscle strength and size in clinical populations.

Anterior cruciate ligament (ACL) rupture is a highly prevalent orthopedic injury, resulting in substantial skeletal muscle atrophy because of changes in muscle protein balance and satellite cell abundance. Neural activation problems also contribute to strength loss, impacting upon a patients’ physical function and rehabilitative capacity. Heavy loads typically required for muscle hypertrophy and strength adaptations are contraindicated because of graft strain and concomitant cartilage, meniscal, and bone pathologies associated with ACL reconstruction. Strength of the quadriceps is a fundamental component for the ability to reduce shearing and torsional strains on the ACL with ground contact, and forms a critical component of ACL rehabilitation. Given the dangers of early postoperative heavy-loading, low-load blood flow restriction (BFR) training may provide an alternative rehabilitation tool for practitioners. Passive BFR can attenuate early muscle atrophy and strength loss, and may be more effective with the addition of novel, complementary therapies such as neuromuscular electrical stimulation. Upon ambulation, aerobic, and resistance exercise with BFR can stimulate muscle hypertrophy and strength adaptations and resolve activation problems. This may occur through increasing muscle protein synthesis and satellite cell proliferation, decreasing muscle protein breakdown and improving muscle activation by altered recruitment patterns. Thus, BFR training may provide an effective rehabilitation tool that does not place heavy loads and force through the tibiofemoral joint. This may reduce the risk of damaging the graft, cartilage, meniscus, or other intra-articular structures, providing thorough screening before use is followed by correct, evidence-informed application.

This study investigated the effects of taurine on repeated sprint exercise, performed after fixed incremental ramp exercise to exhaustion at isokinetic high (90 r/min) or low (50 r/min) cadences. In a double-blind, repeated measures design, nine females completed an incremental ramp test to volitional exhaustion, followed by 2 min active recovery and 6 × 10 s sprints on a cycle ergometer, in one of four conditions: high cadence (90 r/min) + taurine (50 mg/kg body mass); high cadence + placebo (3 mg/kg body mass maltodextrin); low cadence (50 r/min) + taurine; low cadence + placebo. Heart rate (HR) and blood lactate concentration B[La] were measured before and after the ramp test and after the sprints. Taurine lowered HR vs. placebo prior to the ramp test (P = 0.004; d = 2.1). There was an effect of condition on ramp performance (P

Taurine is central to many physiological processes, some of which are augmented by exogenous supply and have the potential to facilitate endurance performance; however, its independent effects on performance have not been systematically analysed. To evaluate the effects of isolated oral taurine ingestion on endurance performance and to assess the contribution of (1) the dose and (2) the supplementation period to the ergogenic effect. A search was performed using various databases in September 2017. The studies were screened using search criteria for eligibility. Ten peer-reviewed articles were identified for inclusion. A sub-analysis of time-to-exhaustion (TTE) trials (n = 7) was also performed. The effects of (1) dose and (2) the acute (single dose) or chronic (> 1 day) supplementation periods were assessed using meta-regression. The doses of taurine ranged from 1 to 6 g/day and were provided in single doses and for up to 2 weeks among a range of subjects. Taurine ingestion improved overall endurance performance (Hedges’ g = 0.40, 95% CI 0.12–0.67, P = 0.004), which was similar in TTE trials (Hedges’ g = 0.43, 95% CI 0.12–0.75, P = 0.007). There were no differences between acute or chronic supplementation for the full sample (P = 0.897) or the TTE group (P = 0.896). The dose of taurine did not moderate its effect on endurance performance (P > 0.05). Human endurance performance can be improved by orally ingesting a single dose of taurine in varying amounts (1–6 g).

Purpose:To investigate the effects of caffeine (C), taurine (T), caffeine and taurine coingestion (C +T), or placebo (P) on repeated Wingate cycling performance and associated physiological responses.Methods:Seven male team-sport players participated in a randomized, single-blind, crossover study, where they completed 3 Wingate tests, each separated by 2 min, an hour after ingesting: C (5 mg/kg body mass [BM]), T (50 mg/kg BM), C +T (5 mg/kg BM + 50 mg/kg BM), or P (5 mg/kg BM) in a gelatin capsule. Performance was measured on an ergometer, and blood lactate, perceived exertion, heart rate (HR), mean arterial pressure (MAP), and rate pressure product (RPP) were measured at rest (presupplement), baseline (1 h postsupplement), and during and after exercise.Results:Magnitude-based inferences revealed that all of the supplements increased (smalltomoderate, likely to very likely) mean peak power (MPP), peak power (PP), and mean power (MP) compared to P, with greater MPP, PP, and MP in T compared to C (small, possible). Intrasprint fatigue index (%FIIntra) was greater in T compared to P and C (moderate, likely), and %FIInterwas lower in T compared to C (small, possible). C and C +T increased HR, MAP, and RPP compared to P and T at baseline (moderate tovery large, likely to most likely); however, these only remained higher in C compared to all conditions in the final sprint.Conclusions:T elicited greater improvements in performance compared to P, C, or C +T while reducing the typical chronotropic and pressor effects of C.

he aims of the study were to investigate: 1) fluctuations in kinematic and locomotor-based metabolic power estimates during elite-level under-21 soccer matches and 2) the relationship between temporary fatigue during matches and heart rate (HR) responses to the YO-YO intermittent recovery test 1 (YO-YO IR1). High speed running (HSR), high metabolic load (HML) distances and average metabolic power (AMP) data were collected from 13 elite soccer players during six matches using global positioning systems. Indices of heart rate recovery (HRR60s; HR60s; %HRR60s) were assessed after a submaximal (YO-YO IR1). The peak 5-min period of matches was higher than both the subsequent 5-min period and the match average for all physical variables (P < 0.001). HML distance was greater (P < 0.001) in peak, post-peak and mean 5-min periods compared to HSR. Peak intensity HML distance was related to %HRR60s (r = -0.331) but not AMP (r = -0.273) or HSR distance (r = -0.224). HML distance should be used to monitor fluctuations in intensity during soccer matches. HRR measured after a submaximal YO-YO IR1 has limited potential, in the assessment of the match specific fitness of players.

This study aimed to investigate and compare the magnitude of exercise-induced hypoalgesia (EIH) with low-intensity blood flow restriction (BFR) resistance exercise (RE) at varying pressures to other intensities of resistance exercise and examine endogenous mechanisms of pain reduction. Twelve individuals performed four experimental trials involving unilateral leg press exercise in a randomized crossover design: low-load RE at 30% of one repetition maximum (1RM), high-load RE (70% 1RM), and BFR-RE (30% 1RM) at a low and high pressure. BFR pressure was prescribed relative to limb occlusion pressure at 40% and 80% for the low- and high-pressure trials. Pressure pain thresholds (PPT) were assessed before and 5 min and 24 h following exercise in exercising and nonexercising muscles. Venous blood samples were collected at the same timepoints to determine plasma concentrations of beta-endorphin and 2-arachidonoylglycerol. High-pressure BFR-RE increased PPTs in the exercising limb to a greater extent than all other trials. Comparable systemic EIH effects were observed with HLRE and both BFR-RE trials. PPTs in the exercising limb remained elevated above baseline at 24 h postexercise following both BFR-RE trials. Postexercise plasma beta-endorphin concentration was elevated during the BFR-RE trials. No changes to 2-arachidonoylglycerol concentration were observed. High pressure BFR-RE causes a greater EIH response in the exercising limb that persists for up to 24 h following exercise. The reduction in pain sensitivity with BFR-RE is partly driven by endogenous opioid production of beta-endorphin. BFR-RE should be investigated as a possible pain-modulation tool in individuals with acute and chronic pain. NEW & NOTEWORTHY High-pressure blood flow restriction (BFR) causes a greater hypoalgesia response in the exercising limb (48%) compared with light and heavy load resistance exercise (10–34%). Performing light load resistance exercise with BFR causes systemic hypoalgesia comparable with heavy load resistance exercise (10–18%). BFR resistance exercise prolonged the exercise-induced hypoalgesia response for 24 h in the exercising limb (15% and 24%, respectively). Activation of endogenous opioid production and a conditioned pain modulation effect partly mediate the relationship between exercise and hypoalgesia.

In the published article, there was an error regarding the affiliation for JohnnyOwens. His affiliation is reported as Owens Recovery Science. We would like to add that this is a private company who run educational courses on the topic area. A correction has therefore been made to the Conflict of Interest Statement: “The authors declare a potential conflict of interest. JO is affiliated withOwens Recovery Science. This is a private company who run educational courses on the topic area. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.” In addition to the above, after concerns were raised regarding the use of the phrase “Position Stand,” the original article has been updated accordingly. Also the word “Position Stand” must be removed from the article title. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Previous injury is associated with increased risk of future injury. Residual inter‐limb deficits are a potential contributing factor leading to compensatory movement patterns on return to sport. The purpose of this study was to examine the effects of previous severe injury on bilateral ground reaction force asymmetries measured during a countermovement jump using a dual force platform. A total of 34 male professional soccer players (age 19 ± 2 years) were subdivided into two groups; previous severe injury (N = 17) or no severe injury (N = 17). Previously injured players showed significantly greater asymmetry in concentric phase variables (P < 0.05) with strong effect sizes (range = 0.99‐1.35). These players also showed significantly elevated asymmetry in eccentric phase variables (P < 0.05) and medium to large effect sizes (range = 0.73‐1.05), with the exception of eccentric deceleration impulse (P > 0.05; d = 0.33). There were no significant between‐group differences in bilateral jump performance parameters (P > 0.05). These data indicate that despite being cleared to return to sport, participating in elite‐level training, full competition and exhibiting no decrements in jump performance, significant inter‐limb asymmetries persist in the concentric and eccentric phases of the CMJ.

Blood flow restriction (BFR) has been shown to produce beneficial adaptations to skeletal muscle. These adaptations have been documented in the civilian and military populations. BFR therapy may provide patients a safe method to begin strength training at earlier stages of rehabilitation to allow for earlier and more effective return to activity and improved military readiness. The purpose was to review BFR therapy physiology, complications, side effects, standardized treatment algorithms, and long-term patient outcomes.

Background Forty per cent of critically ill patients are affected by intensive care unit-acquired weakness (ICU-AW), to which skeletal muscle wasting makes a substantial contribution. This can impair outcomes in hospital, and can cause long-term physical disability after hospital discharge. No effective mitigating strategies have yet been identified. Application of a repetitive vascular occlusion stimulus (RVOS) a limb pressure cuff inducing brief repeated cycles of ischaemia and reperfusion, can limit disuse muscle atrophy in both healthy controls and bed-bound patients recovering from knee surgery. We wish to determine whether RVOS might be effective in mitigating against muscle wasting in the ICU. Given that RVOS can also improve vascular function in healthy controls, we also wish to assess such effects in the critically ill. We here describe a pilot study to assess whether RVOS application is safe, tolerable, feasible and acceptable for ICU patients. Methods This is a randomised interventional feasibility trial. Thirty-two ventilated adult ICU patients with multiorgan failure will be recruited within 48 h of admission and randomised to either the intervention arm or the control arm. Intervention participants will receive RVOS twice daily (except only once on day 1) for up to 10 days or until ICU discharge. Serious adverse events and tolerability (pain score) will be recorded; feasibility of trial procedures will be assessed against pre-specified criteria and acceptability by semi-structured interview. Together with vascular function, muscle mass and quality will be assessed using ultrasound and measures of physical function at baseline, on days 6 and 11 of study enrolment, and at ICU and hospital discharge. Blood and urine biomarkers of muscle metabolism, vascular function, inflammation and DNA damage/repair mechanism will also be analysed. The Health questionnaire will be completed 3 months after hospital discharge. Discussion If this study demonstrates feasibility, the derived data will be used to inform the design (and sample size) of an appropriately-powered prospective trial to clarify whether RVOS can help preserve muscle mass/improve vascular function in critically ill patients. Trial registration ISRCTN Registry, ISRCTN44340629. Registered on 26 October 2017. Electronic supplementary material The online version of this article (10.1186/s13063-019-3547-5) contains supplementary material, which is available to authorized users.

We implemented a blood flow restriction resistance training (BFR-RT) intervention during an 8-week rehabilitation programme in anterior cruciate ligament reconstruction (ACLR) patients within a National Health Service setting. To compare the effectiveness of BFR-RT and standard-care traditional heavy-load resistance training (HL-RT) at improving skeletal muscle hypertrophy and strength, physical function, pain and effusion in ACLR patients following surgery. 28 patients scheduled for unilateral ACLR surgery with hamstring autograft were recruited for this parallel-group, two-arm, single-assessor blinded, randomised clinical trial following appropriate power analysis. Following surgery, a criteria-driven approach to rehabilitation was utilised and participants were block randomised to either HL-RT at 70% repetition maximum (1RM) (n = 14) or BFR-RT (n = 14) at 30% 1RM. Participants completed 8 weeks of biweekly unilateral leg press training on both limbs, totalling 16 sessions, alongside standard hospital rehabilitation. Resistance exercise protocols were designed consistent with standard recommended protocols for each type of exercise. Scaled maximal isotonic strength (10RM), muscle morphology of the vastus lateralis of the injured limb, self-reported function, Y-balance test performance and knee joint pain, effusion and range of motion (ROM) were assessed at pre-surgery, post-surgery, mid-training and post-training. Knee joint laxity and scaled maximal isokinetic knee extension and flexion strength at 60°/s, 150°/s and 300°/s were measured at pre-surgery and post-training. Four participants were lost, with 24 participants completing the study (12 per group). There were no adverse events or differences between groups for any baseline anthropometric variable or pre- to post-surgery change in any outcome measure. Scaled 10RM strength significantly increased in the injured limb (104 ± 30% and 106 ± 43%) and non-injured limb (33 ± 13% and 39 ± 17%) with BFR-RT and HL-RT, respectively, with no group differences. Significant increases in knee extension and flexion peak torque were observed at all speeds in the non-injured limb with no group differences. Significantly greater attenuation of knee extensor peak torque loss at 150°/s and 300°/s and knee flexor torque loss at all speeds was observed with BFR-RT. No group differences in knee extensor peak torque loss were found at 60°/s. Significant and comparable increases in muscle thickness (5.8 ± 0.2% and 6.7 ± 0.3%) and pennation angle (4.1 ± 0.3% and 3.4 ± 0.1%) were observed with BFR-RT and HL-RT, respectively, with no group differences. No significant changes in fascicle length were observed. Significantly greater and clinically important increases in several measures of self-reported function (50-218 ± 48% vs. 35-152 ± 56%), Y-balance performance (18-59 ± 22% vs. 18-33 ± 19%), ROM (78 ± 22% vs. 48 ± 13%) and reductions in knee joint pain (67 ± 15% vs. 39 ± 12%) and effusion (6 ± 2% vs. 2 ± 2%) were observed with BFR-RT compared to HL-RT, respectively. BFR-RT can improve skeletal muscle hypertrophy and strength to a similar extent to HL-RT with a greater reduction in knee joint pain and effusion, leading to greater overall improvements in physical function. Therefore, BFR-RT may be more appropriate for early rehabilitation in ACLR patient populations within the National Health Service.

Examine the comfort and pain experienced with blow flow restriction resistance training (BFR-RT) compared to standard care heavy load resistance training (HL-RT) during anterior cruciate ligament reconstruction (ACLR) patient rehabilitation. Randomised controlled trial. United Kingdom National Health Service. Twenty eight patients undergoing unilateral ACLR surgery with hamstring autograft were recruited. Following surgery participants were block randomised to either HL-RT at 70% repetition maximum (1RM) (n = 14) or BFR-RT (n = 14) at 30% 1RM and completed 8 weeks of twice weekly unilateral leg press training on both limbs. Perceived knee pain, muscle pain and rating of perceived exertion (RPE) were assessed using Borg's (1998) RPE and pain scales during training. Knee pain was also assessed 24 h post-training. There were no adverse events. Knee pain was lower with BFR-RT during (p 0.05) for both BFR-RT and HL-RT. ACLR patients experienced less knee joint pain and reported similar ratings of perceived exertion during and following leg press exercise with BFR-RT compared to traditional HL-RT. BFR-RT may be more advantageous during the early phases of post-surgery ACLR rehabilitation. [Abstract copyright: Copyright © 2019. Published by Elsevier Ltd.]

Waddingham, DP, Millyard, A, Patterson, SD, and Hill, J. Effect of ballistic potentiation protocols on elite sprint swimming: optimizing performance. J Strength Cond Res 35(10): 2833-2838, 2021-Warming-up before an athletic event is important for performance; however, in some competition scenarios, there is a long wait between completing the warm-up and the event. Thus, potentiation protocols are becoming increasingly popular in a competition environment. The aim of the study was to determine the effects of practical potentiation protocols on 15-m start performance in national level swimmers. Eleven national level swimmers participated in the study. Using a randomized cross-over design, subjects completed a 15-m swimming start following 4 different experimental conditions (swim-specific control, resisted band squat, weighted countermovement jumps, and drop jumps from a 45-cm box), each separated by at least 48 hours. A repeated-measures analysis of variance showed a significant difference in 15-m swimming start performance following different warm-up protocols (F(1.646, 14.810) = 6.968, p = 0.01). A post hoc Bonferroni test indicated that 15-m start time was significantly quicker with the band squat protocol compared with the swim-specific protocol (6.65 ± 0.43 vs. 6.78 ± 0.43 seconds, respectively, p = 0.04). The results conclude that practical potentiation protocols are able to enhance 15-m swim start performance when combined with a swim-specific warm-up and supports the use of postactivation potentiation during competitive swimming environments.

Madison, G, Patterson, SD, Read, P, Howe, L, and Waldron, M. Effects of small-sided game variation on changes in hamstring strength. J Strength Cond Res 33(3): 839-845, 2019-Small-sided games (SSGs) are commonly used by soccer practitioners to condition players. This form of exercise can result in fatigue, potentially exposing the muscle to injury risk. The purpose of this study was to determine the effects of SSG variations on hamstring torque in semiprofessional soccer players. In a counterbalanced cross-over design, 10 male semiprofessional soccer players took part in both small relative area (3 vs. 3; 300 m) and large relative area (4 vs. 4; 1000 m) SSGs. The games comprised 6 × 4-minute bouts, with 90-second recovery. Both movement and heart rate responses were monitored by global positioning systems (GPS) and hamstring isometric torque was measured pre-training and post-training using a NordBord. There were differences (p < 0.05) between the small and large relative area games for peak hamstring force decrement (5.78 N and -13.62 N, respectively) and mean hamstring force decrement at 90° (11.11 N and -4.78 N, respectively). The number of accelerations was related to (r = 0.46, p = 0.039) reduced hamstring peak torque at 90°. In conclusion, larger relative area SSGs elicited the greatest internal and external loads, resulting in decrements in hamstring force. The number of accelerations performed in the session increases the likelihood of hamstring fatigue and can be controlled with the relative pitch area.