Search

Your search keyword '"Stephanou, Euripides G."' showing total 369 results
Start Over Author "Stephanou, Euripides G."
369 results on '"Stephanou, Euripides G."'

11. Development of West-European PM2.5 and NO2 land use regression models incorporating satellite-derived and chemical transport modelling data

Author

de Hoogh, Kees, Gulliver, John, Donkelaar, Aaron van, Martin, Randall V., Marshall, Julian D., Bechle, Matthew J., Cesaroni, Giulia, Pradas, Marta Cirach, Dedele, Audrius, Eeftens, Marloes, Forsberg, Bertil, Galassi, Claudia, Heinrich, Joachim, Hoffmann, Barbara, Jacquemin, Bénédicte, Katsouyanni, Klea, Korek, Michal, Künzli, Nino, Lindley, Sarah J., Lepeule, Johanna, Meleux, Frederik, de Nazelle, Audrey, Nieuwenhuijsen, Mark, Nystad, Wenche, Raaschou-Nielsen, Ole, Peters, Annette, Peuch, Vincent-Henri, Rouil, Laurence, Udvardy, Orsolya, Slama, Rémy, Stempfelet, Morgane, Stephanou, Euripides G., Tsai, Ming Y., Yli-Tuomi, Tarja, Weinmayr, Gudrun, Brunekreef, Bert, Vienneau, Danielle, and Hoek, Gerard

Published
2016
Full Text
View/download PDF

13. Occurrence of DBPs in Drinking Water of European Regions for Epidemiology Studies

Author

KRASNER, STUART W., KOSTOPOULOU, MARIA, TOLEDANO, MIREILLE B., WRIGHT, JOHN, PATELAROU, EVRIDIKI, KOGEVINAS, MANOLIS, VILLANUEVA, CRISTINA M., CARRASCO-TURIGAS, GLÒRIA, MARINA, LORETO SANTA, FERNÁNDEZ-SOMOANO, ANA, BALLESTER, FERRAN, TARDON, ADONINA, GRAZULEVICIENE, REGINA, DANILEVICIUTE, ASTA, CORDIER, SYLVAINE, COSTET, NATHALIE, RIGHI, ELENA, AGGAZZOTTI, GABRIELLA, STEPHANOU, EURIPIDES G., KARGAKI, SOPHIA, and NIEUWENHUIJSEN, MARK J.

Published
2016

14. Ocean–Atmosphere Interactions of Particles

Author

de Leeuw, Gerrit, Guieu, Cécile, Arneth, Almuth, Bellouin, Nicolas, Bopp, Laurent, Boyd, Philip W., van der Gon, Hugo A. C. Denier, Desboeufs, Karine V., Dulac, François, Facchini, M. Cristina, Gantt, Brett, Langmann, Baerbel, Mahowald, Natalie M., Marañón, Emilio, O’Dowd, Colin, Olgun, Nazli, Pulido-Villena, Elvira, Rinaldi, Matteo, Stephanou, Euripides G., Wagener, Thibaut, Liss, Peter S., editor, and Johnson, Martin T., editor

Published
2014
Full Text
View/download PDF

17. Trihalomethanes in Drinking Water and Bladder Cancer Burden in the European Union

Author

Evlampidou, Iro, Font-Ribera, Laia, Rojas-Rueda, David, Gracia-Lavedan, Esther, Coste, Nathalie, Pearce, Neil, Vineis, Paolo, Jaakkola, Jouni J.K., Delloye, Francis, Makris, Konstantinos C., Stephanou, Euripides G., Kargaki, Sophia, Kozisek, Frantisek, Sigsgaard, Torben, Hansen, Birgitte, Schullehner, Jorg, Nahkur, Ramon, Galey, Catherine, Zwiener, Christian, Vargha, Marta, Righi, Elena, Aggazzotti, Gabriella, Kalnina, Gunda, Grazuleviciene, Regina, Polanska, Kinga, Gubkova, Dasa, Bitenc, Katarina, Goslan, Emma H., Kogevinas, Manolis, and Villanueva, Cristina M.

Subjects
United States. Environmental Protection Agency -- Officials and employees, Bladder cancer, Cancer research, Trihalomethanes, Drinking water, Infection control, Water, Medical research, Diseases, Environmental issues, Health, European Union -- Officials and employees, European Union. European Council -- Officials and employees, World Health Organization -- Officials and employees
Abstract

Background: Trihalomethanes (THMs) are widespread disinfection by-products (DBPs) in drinking water, and long-term exposure has been consistently associated with increased bladder cancer risk. OBJECTIVE: We assessed THM levels in drinking water in the European Union as a marker of DBP exposure and estimated the attributable burden of bladder cancer. METHODS: We collected recent annual mean THM levels in municipal drinking water in 28 European countries (EU28) from routine monitoring records. We estimated a linear exposure-response function for average residential THM levels and bladder cancer by pooling data from studies included in the largest international pooled analysis published to date in order to estimate odds ratios (ORs) for bladder cancer associated with the mean THM level in each country (relative to no exposure), population-attributable fraction (PAF), and number of attributable bladder cancer cases in different scenarios using incidence rates and population from the Global Burden of Disease study of 2016. Results: We obtained 2005-2018 THM data from EU26, covering 75% of the population. Data coverage and accuracy were heterogeneous among countries. The estimated population-weighted mean THM level was 11.7 [micro]g/L [standard deviation (SD) of 11.2]. The estimated bladder cancer PAF was 4.9% [95% confidence interval (CI): 2.5, 7.1] overall (range: 0-23%), accounting for 6,561 (95% CI: 3,389, 9,537) bladder cancer cases per year. Denmark and the Netherlands had the lowest PAF (0.0% each), while Cyprus (23.2%), Malta (17.9%), and Ireland (17.2%) had the highest among EU26. In the scenario where no country would exceed the current EU mean, 2,868 (95% CI: 1,522, 4,060; 43%) annual attributable bladder cancer cases could potentially be avoided. Discussion: Efforts have been made to reduce THM levels in the European Union. However, assuming a causal association, current levels in certain countries still could lead to a considerable burden of bladder cancer that could potentially be avoided by optimizing water treatment, disinfection, and distribution practices, among other possible measures. https://doi.org/10.1289/EHP4495, Introduction Drinking water disinfection is essential for public health protection against waterborne infections. However, disinfection byproducts (DBPs) are formed as an unintended consequence of water disinfection. DBPs form a complex [...]

Published
2020
Full Text
View/download PDF

18. Air Pollution During Pregnancy and Childhood Cognitive and Psychomotor Development: Six European Birth Cohorts

Author

Guxens, Mònica, Garcia-Esteban, Raquel, Giorgis-Allemand, Lise, Forns, Joan, Badaloni, Chiara, Ballester, Ferran, Beelen, Rob, Cesaroni, Giulia, Chatzi, Leda, de Agostini, Maria, de Nazelle, Audrey, Eeftens, Marloes, Fernandez, Mariana F., Fernández-Somoano, Ana, Forastiere, Francesco, Gehring, Ulrike, Ghassabian, Akhgar, Heude, Barbara, Jaddoe, Vincent W. V., Klümper, Claudia, Kogevinas, Manolis, Krämer, Ursula, Larroque, Béatrice, Lertxundi, Aitana, Lertxuni, Nerea, Murcia, Mario, Navel, Vladislav, Nieuwenhuijsen, Mark, Porta, Daniela, Ramos, Rosa, Roumeliotaki, Theano, Slama, Rémy, Sørensen, Mette, Stephanou, Euripides G., Sugiri, Dorothea, Tardón, Adonina, Tiemeier, Henning, Tiesler, Carla M. T., Verhulst, Frank C., Vrijkotte, Tanja, Wilhelm, Michael, Brunekreef, Bert, Pershagen, Göran, and Sunyer, Jordi

Published
2014

19. Polycyclic aromatic hydrocarbons (PAHs) and their alkylated, nitrated and oxygenated derivatives in the atmosphere over the Mediterranean and Middle East seas

Author

Wietzoreck, Marco, primary, Kyprianou, Marios, additional, Musa Bandowe, Benjamin A., additional, Celik, Siddika, additional, Crowley, John N., additional, Drewnick, Frank, additional, Eger, Philipp, additional, Friedrich, Nils, additional, Iakovides, Minas, additional, Kukučka, Petr, additional, Kuta, Jan, additional, Nežiková, Barbora, additional, Pokorná, Petra, additional, Přibylová, Petra, additional, Prokeš, Roman, additional, Rohloff, Roland, additional, Tadic, Ivan, additional, Tauer, Sebastian, additional, Wilson, Jake, additional, Harder, Hartwig, additional, Lelieveld, Jos, additional, Pöschl, Ulrich, additional, Stephanou, Euripides G., additional, and Lammel, Gerhard, additional

Published
2022
Full Text
View/download PDF

20. Cohort Profile: The Mother-Child Cohort in Crete, Greece (Rhea Study)

Author

Chatzi, Leda, Leventakou, Vasiliki, Vafeiadi, Marina, Koutra, Katerina, Roumeliotaki, Theano, Chalkiadaki, Georgia, Karachaliou, Marianna, Daraki, Vasiliki, Kyriklaki, Andriani, Kampouri, Mariza, Fthenou, Eleni, Sarri, Katerina, Vassilaki, Maria, Fasoulaki, Maria, Bitsios, Panos, Koutis, Antonis, Stephanou, Euripides G, and Kogevinas, Manolis

Published
2017
Full Text
View/download PDF

21. Variation of NO2 and NOx concentrations between and within 36 European study areas: Results from the ESCAPE study

Author

Cyrys, Josef, Eeftens, Marloes, Heinrich, Joachim, Ampe, Christophe, Armengaud, Alexandre, Beelen, Rob, Bellander, Tom, Beregszaszi, Timea, Birk, Matthias, Cesaroni, Giulia, Cirach, Marta, de Hoogh, Kees, De Nazelle, Audrey, de Vocht, Frank, Declercq, Christophe, Dėdelė, Audrius, Dimakopoulou, Konstantina, Eriksen, Kirsten, Galassi, Claudia, Grąulevičienė, Regina, Grivas, Georgios, Gruzieva, Olena, Gustafsson, Annika Hagenbjörk, Hoffmann, Barbara, Iakovides, Minas, Ineichen, Alex, Krämer, Ursula, Lanki, Timo, Lozano, Patricia, Madsen, Christian, Meliefste, Kees, Modig, Lars, Mölter, Anna, Mosler, Gioia, Nieuwenhuijsen, Mark, Nonnemacher, Michael, Oldenwening, Marieke, Peters, Annette, Pontet, Sabrina, Probst-Hensch, Nicole, Quass, Ulrich, Raaschou-Nielsen, Ole, Ranzi, Andrea, Sugiri, Dorothee, Stephanou, Euripides G., Taimisto, Pekka, Tsai, Ming-Yi, Vaskövi, Éva, Villani, Simona, Wang, Meng, Brunekreef, Bert, and Hoek, Gerard

Published
2012
Full Text
View/download PDF

27. Supplementary material to "Polycyclic aromatic hydrocarbons (PAHs) and their alkylated-, nitro- and oxy-derivatives in the atmosphere over the Mediterranean and Middle East seas"

Author

Wietzoreck, Marco, primary, Kyprianou, Marios, additional, Bandowe, Benjamin A. Musa, additional, Celik, Siddika, additional, Crowley, John N., additional, Drewnick, Frank, additional, Eger, Philipp, additional, Friedrich, Nils, additional, Iakovides, Minas, additional, Kukučka, Petr, additional, Kuta, Jan, additional, Nežiková, Barbora, additional, Pokorná, Petra, additional, Přibylová, Petra, additional, Prokeš, Roman, additional, Rohloff, Roland, additional, Tadic, Ivan, additional, Tauer, Sebastian, additional, Wilson, Jake, additional, Harder, Hartwig, additional, Lelieveld, Jos, additional, Pöschl, Ulrich, additional, Stephanou, Euripides G., additional, and Lammel, Gerhard, additional

Published
2022
Full Text
View/download PDF

32. Sex specific associations between in utero exposure to persistent organic pollutants and allergy-related outcomes in childhood: The Rhea Mother–Child Cohort (Crete, Greece)

Author

Margetaki, Katerina, primary, Alexaki, Maria, additional, Vittorakis, Evangelos, additional, Roumeliotaki, Theano, additional, Leventakou, Vasiliki, additional, Bempi, Vicky, additional, Chalkiadaki, Georgia, additional, Kyrtopoulos, Soterios A., additional, Rantakokko, Panu, additional, Kiviranta, Hannu, additional, Stephanou, Euripides G., additional, Kogevinas, Manolis, additional, Chatzi, Leda, additional, and Vafeiadi, Marina, additional

Published
2021
Full Text
View/download PDF

35. Sex specific associations between in utero exposure to persistent organic pollutants and allergy-related outcomes in childhood: The Rhea Mother–Child Cohort (Crete, Greece).

Author

Margetaki, Katerina, Alexaki, Maria, Vittorakis, Evangelos, Roumeliotaki, Theano, Leventakou, Vasiliki, Bempi, Vicky, Chalkiadaki, Georgia, Kyrtopoulos, Soterios A., Rantakokko, Panu, Kiviranta, Hannu, Stephanou, Euripides G., Kogevinas, Manolis, Chatzi, Leda, and Vafeiadi, Marina

Subjects
PERSISTENT pollutants, CHILD development, PRENATAL exposure, POISSON regression, ASTHMA in children
Abstract

Accumulating evidence suggests that in utero exposures can influence the development of the immune system. Few studies have investigated whether prenatal exposure to persistent organic pollutants (POPs) is associated with allergy-related phenotypes in childhood, nor explored sex differences. We examined the association between prenatal exposure to POPs and offspring allergic outcomes in early and mid-childhood. We included 682 mother–child pairs from the prospective birth cohort Rhea. We measured dichlorodiphenyldichloroethylene (DDE), hexachlorobenzene (HCB) and 6 polychlorinated biphenyl (PCB) congeners in maternal first trimester serum. Parents completed the questionnaires adapted from the International Study on Asthma and Allergy in Childhood (ISAAC) for allergy-related phenotypes when their children were 4 and 6 years old. We used Poisson regression models to estimate Risk Ratios. Prenatal HCB was associated with increased risk for rhinoconjunctivitis at 6 years (RR (95% CI): 2.5; (1.3, 4.8) for a doubling in the exposure). Among girls, prenatal DDE was associated with increased risk for current wheeze, current asthma and current rhinoconjunctivitis at 4 years (RR (95%CI): 1.4 (0.8, 2.6), 1.6 (1.1, 2.4) and 1.8 (1.0, 3.3) and p-interaction = 0.035, 0.027 and 0.059, respectively), with increased risk for current rhinoconjunctivitis at 6 years (RR (95%CI): 1.7 (0.7, 3.8) and p-interaction = 0.028) and total PCBs were associated with increased risk for current eczema at 4 years (RR (95%CI): 2.1 (1.1, 4.2) and p-interaction = 0.028). In boys, prenatal DDE was associated with decreased risk for current wheeze and current asthma at 4 years. Our findings suggest that even low levels of exposure to POPs prenatally may affect the development of childhood allergy-related outcomes in a sex and age-specific manner. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

37. Ocean–Atmosphere Interactions of Particles

Author

de Leeuw, Gerrit, primary, Guieu, Cécile, additional, Arneth, Almuth, additional, Bellouin, Nicolas, additional, Bopp, Laurent, additional, Boyd, Philip W., additional, van der Gon, Hugo A. C. Denier, additional, Desboeufs, Karine V., additional, Dulac, François, additional, Facchini, M. Cristina, additional, Gantt, Brett, additional, Langmann, Baerbel, additional, Mahowald, Natalie M., additional, Marañón, Emilio, additional, O’Dowd, Colin, additional, Olgun, Nazli, additional, Pulido-Villena, Elvira, additional, Rinaldi, Matteo, additional, Stephanou, Euripides G., additional, and Wagener, Thibaut, additional

Published
2013
Full Text
View/download PDF

41. Pre-diagnostic blood immune markers, incidence and progression of B-cell lymphoma and multiple myeloma: Univariate and functionally informed multivariate analyses

Author

Vermeulen, Roel, Saberi Hosnijeh, Fatemeh, Bodinier, Barbara, Portengen, Lützen, Liquet, Benoît, Garrido-Manriquez, Javiera, Lokhorst, Henk, Bergdahl, Ingvar A, Kyrtopoulos, Soterios A, Johansson, Ann-Sofie, Georgiadis, Panagiotis, Melin, Beatrice, Palli, Domenico, Krogh, Vittorio, Panico, Salvatore, Sacerdote, Carlotta, Tumino, Rosario, Vineis, Paolo, Castagné, Raphaële, Chadeau-Hyam, Marc, Botsivali, Maria, Chatziioannou, Aristotelis, Valavanis, Ioannis, Kleinjans, Jos C S, de Kok, Theo M C M, Keun, Hector C, Athersuch, Toby J, Kelly, Rachel, Lenner, Per, Hallmans, Göran, Stephanou, Euripides G, Myridakis, Antonis, Kogevinas, Manolis, Fazzo, Lucia, De Santis, Marco, Comba, Pietro, Bendinelli, Benedetta, Kiviranta, Hannu, Rantakokko, Panu, Airaksinen, Riikka, Ruokojarvi, Paivi, Gilthorpe, Mark, Fleming, Sarah, Fleming, Thomas, Tu, Yu-Kang, Lundh, Thomas, Chien, Kuo-Liong, Chen, Wei J, Lee, Wen-Chung, Kate Hsiao, Chuhsing, Kuo, Po-Hsiu, Hung, Hung, Liao, Shu-Fen, Vermeulen, Roel, Saberi Hosnijeh, Fatemeh, Bodinier, Barbara, Portengen, Lützen, Liquet, Benoît, Garrido-Manriquez, Javiera, Lokhorst, Henk, Bergdahl, Ingvar A, Kyrtopoulos, Soterios A, Johansson, Ann-Sofie, Georgiadis, Panagioti, Melin, Beatrice, Palli, Domenico, Krogh, Vittorio, Panico, Salvatore, Sacerdote, Carlotta, Tumino, Rosario, Vineis, Paolo, Castagné, Raphaële, Chadeau-Hyam, Marc, Botsivali, Maria, Chatziioannou, Aristoteli, Valavanis, Ioanni, Kleinjans, Jos C S, de Kok, Theo M C M, Keun, Hector C, Athersuch, Toby J, Kelly, Rachel, Lenner, Per, Hallmans, Goran, Stephanou, Euripides G, Myridakis, Antoni, Kogevinas, Manoli, Fazzo, Lucia, De Santis, Marco, Comba, Pietro, Bendinelli, Benedetta, Kiviranta, Hannu, Rantakokko, Panu, Airaksinen, Riikka, Ruokojarvi, Paivi, Gilthorpe, Mark, Fleming, Sarah, Fleming, Thoma, Tu, Yu-Kang, Lundh, Thoma, Chien, Kuo-Liong, Chen, Wei J, Lee, Wen-Chung, Kate Hsiao, Chuhsing, Kuo, Po-Hsiu, Hung, Hung, Liao, Shu-Fen, One Health Chemisch, dIRAS RA-2, Sub Physical Oceanography, and Immunology

Subjects
Adult, Male, Vascular Endothelial Growth Factor A, multivariate model, prospective cohort, lymphoma, multivariate models, cytokine, Humans, Prospective Studies, Chemokine CCL7, Aged, Cancer och onkologi, mixed-effect modeling, Chemokine CX3CL1, Incidence, mixed‐effect modeling, Middle Aged, Transforming Growth Factor alpha, Prognosis, time to diagnosis, Europe, multiple myeloma, Case-Control Studies, Cancer and Oncology, Multivariate Analysis, Female, Fibroblast Growth Factor 2, Lymphoma, Large B-Cell, Diffuse, Biomarkers, Cancer Epidemiology, Follow-Up Studies
Abstract

Recent prospective studies have shown that dysregulation of the immune system may precede the development of B‐cell lymphomas (BCL) in immunocompetent individuals. However, to date, the studies were restricted to a few immune markers, which were considered separately. Using a nested case–control study within two European prospective cohorts, we measured plasma levels of 28 immune markers in samples collected a median of 6 years before diagnosis (range 2.01–15.97) in 268 incident cases of BCL (including multiple myeloma [MM]) and matched controls. Linear mixed models and partial least square analyses were used to analyze the association between levels of immune marker and the incidence of BCL and its main histological subtypes and to investigate potential biomarkers predictive of the time to diagnosis. Linear mixed model analyses identified associations linking lower levels of fibroblast growth factor‐2 (FGF‐2 p = 7.2 × 10−4) and transforming growth factor alpha (TGF‐α, p = 6.5 × 10−5) and BCL incidence. Analyses stratified by histological subtypes identified inverse associations for MM subtype including FGF‐2 (p = 7.8 × 10−7), TGF‐α (p = 4.08 × 10−5), fractalkine (p = 1.12 × 10−3), monocyte chemotactic protein‐3 (p = 1.36 × 10−4), macrophage inflammatory protein 1‐alpha (p = 4.6 × 10−4) and vascular endothelial growth factor (p = 4.23 × 10−5). Our results also provided marginal support for already reported associations between chemokines and diffuse large BCL (DLBCL) and cytokines and chronic lymphocytic leukemia (CLL). Case‐only analyses showed that Granulocyte‐macrophage colony stimulating factor levels were consistently higher closer to diagnosis, which provides further evidence of its role in tumor progression. In conclusion, our study suggests a role of growth‐factors in the incidence of MM and of chemokine and cytokine regulation in DLBCL and CLL., What's new? B‐cell lymphomas (BCL) are frequent in immunocompromised individuals, but most BCL cases are thought to occur as a consequence of minor immune perturbations in otherwise immunocompetent individuals. Here the authors prospectively examined a panel of immune markers in the blood from 268 patients afflicted with BCL and paired controls. The data uncover a functional role for growth factors (i.e. FGF‐2, TGF‐alpha) in the incidence and progression of multiple myeloma, a BCL subtype, and underscore the importance of chemokine and cytokine regulation in diffuse large B‐cell lymphoma and chronic lymphocytic leukemia.

Published
2018

44. DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia

Author

Georgiadis, Panagiotis, Gavriil, Marios, Rantakokko, Panu, Ladoukakis, Efthymios, Botsivali, Maria, Kelly, Rachel S., Bergdahl, Ingvar A., Kiviranta, Hannu, Vermeulen, Roel C. H., Spaeth, Florentin, Hebbels, Dennie G. A. J., Kleinjans, Jos C. S., de Kok, Theo M. C. M., Palli, Domenico, Vineis, Paolo, Kyrtopoulos, Soterios A., Gottschalk, Ralph, van Leeuwen, Danitsja, Timmermans, Leen, Bendinelli, Benedetta, Portengen, Lutzen, Saberi-Hosnijeh, Fatemeh, Melin, Beatrice, Hallmans, Goran, Lenner, Per, Keun, Hector C., Siskos, Alexandros, Athersuch, Toby J., Kogevinas, Manolis, Stephanou, Euripides G., Myridakis, Antonis, Fazzo, Lucia, De Santis, Marco, Comba, Pietro, Airaksinen, Riikka, Ruokojarvi, Paivi, Gilthorpe, Mark, Fleming, Sarah, Fleming, Thomas, Tu, Yu-Kang, Jonsson, Bo, Lundh, Thomas, Chen, Wei J., Lee, Wen-Chung, Hsiao, Chuhsing Kate, Chien, Kuo-Liong, Kuo, Po-Hsiu, Hung, Hung, Liao, Shu-Fen, Toxicogenomics, RS: GROW - R1 - Prevention, RS: FSE MaCSBio, RS: FPN MaCSBio, RS: FHML MaCSBio, RS: MHeNs - R3 - Neuroscience, and Commission of the European Communities

Subjects
Male, EnviroGenomarkers consortium, HYPOMETHYLATION, 010501 environmental sciences, medicine.disease_cause, 01 natural sciences, Pathogenesis, Blood plasma, LYMPHOMA, skin and connective tissue diseases, lcsh:Environmental sciences, General Environmental Science, lcsh:GE1-350, RISK, 0303 health sciences, DNA methylation, ROLES, B-cell lymphoma, Melanoma, Persistent organic pollutants, Middle Aged, Polychlorinated Biphenyls, CANCER, 3. Good health, Italy, Molecular epidemiology, Female, Stem cell, Adult, GENES, POLYCOMB, Article, 03 medical and health sciences, Arbetsmedicin och miljömedicin, MD Multidisciplinary, medicine, Humans, Environmental toxicology, Gene, 030304 developmental biology, 0105 earth and related environmental sciences, Sweden, POLYCHLORINATED BIPHENYL EXPOSURES, Occupational Health and Environmental Health, medicine.disease, HYPERMETHYLATION, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, 13. Climate action, Cancer research, sense organs, Carcinogenesis, Hazard assessment, Environmental Sciences
Abstract

Objectives: To characterize the impact of PCB exposure on DNA methylation in peripheral blood leucocytes and to evaluate the corresponding changes in relation to possible health effects, with a focus on B-cell lymphoma. Methods: We conducted an epigenome-wide association study on 611 adults free of diagnosed disease, living in Italy and Sweden, in whom we also measured plasma concentrations of 6 PCB congeners, DDE and hexachlorobenzene. Results: We identified 650 CpG sites whose methylation correlates strongly (FDR

Published
2019

46. Iso- and Anteiso-alkanes: specific tracers of environmental tobacco smoke in indoor and outdoor particle-size distributed urban aerosols

Author

Kavouras, Ilias S., Stratigakis, Nikolaos, and Stephanou, Euripides G.

Subjects
Passive smoking -- Environmental aspects, Indoor air quality -- Research, Pollution -- Measurement, Environmental issues, Science and technology
Abstract

Branched iso- and anteiso-alkenes were shown to be good tracers of environmental tobacco smoke both in indoor and outdoor tobacco smoke determinations. Some of the qualities that make iso- and anteiso-alkenes better tracers than the conventional n-alkenes and polyaromatic hydrocarbon tracers are the non-reactive character of the alkenes, their specificity and long atmospheric residence times, which render the substances readily distinguishable using gas chromatography.

Published
1998

Catalog

Books, media, physical & digital resources
See catalog results