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Your search keyword '"Stepan, Vaclav"' showing total 19 results
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19 results on '"Stepan, Vaclav"'

1. REFLECT – Research flight of EURADOS and CRREAT: Intercomparison of various radiation dosimeters onboard aircraft

Author

Ambrožová, Iva, Beck, Peter, Benton, Eric R., Billnert, Robert, Bottollier-Depois, Jean-Francois, Caresana, Marco, Dinar, Nesrine, Domański, Szymon, Gryziński, Michał A., Kákona, Martin, Kolros, Antonín, Krist, Pavel, Kuć, Michał, Kyselová, Dagmar, Latocha, Marcin, Leuschner, Albrecht, Lillhök, Jan, Maciak, Maciej, Mareš, Vladimír, Murawski, Łukasz, Pozzi, Fabio, Reitz, Guenther, Schennetten, Kai, Silari, Marco, Šlegl, Jakub, Sommer, Marek, Štěpán, Václav, Trompier, Francois, Tscherne, Christoph, Uchihori, Yukio, Vargas, Arturo, Viererbl, Ladislav, Wielunski, Marek, Wising, Mie, Zorloni, Gabriele, and Ploc, Ondřej

Published
2020
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8. DNA damage modeled with Geant4-DNA: effects of plasmid DNA conformation and experimental conditions

Author

Domínguez-Kondo, Jorge Naoki, primary, Moreno, Eduardo Barbosa, additional, Stepan, Vaclav, additional, Stefanová, Klára, additional, Perrot, Yann, additional, Villagrasa, Carmen, additional, Incerti, Sebastien, additional, De Celis Alonso, Benito, additional, Schuemann, Jan, additional, Faddegon, Bruce A, additional, and Ramos-Mendez, Jose, additional

Published
2021
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9. Radiation-induced plasmid DNA damage: Effect of concentration and length

Author

Brabcova, Katerina, Zuzana, Jamborová, Michaelidesova, Anna, Marie, Davídková, Kodaira, Satoshi, Sefl, Martin, Stepan, Vaclav, and Satoshi, Kodaira

Abstract

Plasmid DNA is commonly used as a simpler substitute for a cell in studies of early effects of ionizing radiation because it allows to determine yields of primary DNA lesions. Experimental studies often employ plasmids of different lengths, in different concentrations in the aqueous solution. Influence of these parameters on the heavy-ion induced yields of primary DNA damage has been studied, using plasmids pUC19 (2686 bp), pBR322 (4361 bp) and pKLAC2 (9107 bp) in 10 and 50 ng/μl concentration. Results demonstrate the impact of plasmid length, while no significant difference was observed between the two concentrations. The uncertainty of the results is discussed.

Published
2019

16. Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit

Author

Bernal, Mario A., Bordage, Marie Claude, Brown, Jeremy Michael Cooney, Davídková, Marie, Delage, E., El Bitar, Ziad Ei, Enger, Shirin A., Francis, Ziad, Guatelli, Susanna, Ivanchenko, Vladimir N., Karamitros, Mathieu, Kyriakou, Ioanna, Maigne, Lydia, Meylan, Sylvain, Murakami, Kouichi, Okada, Shogo, Payno, H., Perrot, Yann, Petrović, Ivan M., Pham, Q. T., Ristić-Fira, Aleksandra, Sasaki, Takashi, Stepan, Vaclav, Tran, Ngoc Hoang, Villagrasa, Carmen, and Incerti, Sebastien

Subjects
Ionizing radiation, Geant4-DNA, Radiolysis, Radiobiology, Monte Carlo
Abstract

Understanding the fundamental mechanisms involved in the induction of biological damage by ionizing radiation remains a major challenge of todays radiobiology research. The Monte Carlo simulation of physical, physicochemical and chemical processes involved may provide a powerful tool for the simulation of early damage induction. The Geant4-DNA extension of the general purpose Monte Carlo Geant4 simulation toolkit aims to provide the scientific community with an open source access platform for the mechanistic simulation of such early damage. This paper presents the most recent review of the Geant4-DNA extension, as available to Geant4 users since June 2015 (release 10.2 Beta). In particular, the review includes the description of new physical models for the description of electron elastic and inelastic interactions in liquid water, as well as new examples dedicated to the simulation of physicochemical and chemical stages of water radiolysis. Several implementations of geometrical models of biological targets are presented as well, and the list of Geant4-DNA examples is described.

Published
2015

17. Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study

Author

Incerti, Sebastien, Psaltaki, Maria G., Gillet, Pierre, Barberet, Ph., Bardies, M., Bernal, Mario A., Bordage, Marie Claude, Breton, Vincent, Davídková, Marie, Delage, E., El Bitar, Ziad Ei, Francis, Ziad, Guatelli, Susanna, Ivanchenko, A., Ivanchenko, Vladimir, Karamitros, Mathieu, Lee, Sebyeong, Maigne, Lydia, Meylan, Sylvain, Murakami, Kouichi, Nieminen, Petteri H., Payno, H., Perrot, Yann, Petrović, Ivan M., Pham, Q. T., Ristić-Fira, Aleksandra, Santin, Giovanni, Sasaki, Takashi, Seznec, Herve, Shin, Jae-ik, Stepan, Vaclav, Tran, Ngoc Hoang, Villagrasa, Carmen, Geant4-DNA Collaboration, Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), National Technical University of Athens [Athens] (NTUA), Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Instituto de Fisica 'Gleb Wataghin' (INSTITUTO DE FISICA 'GLEB WATAGHIN'), Universidade Estadual de Campinas (UNICAMP), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Department of Radiation Dosimetry, Nuclear Physics Institute of the AS CR, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Department of Physics, Faculty of Sciences, Université Saint-Joseph de Beyrouth (USJ), Centre for Medical Radiation Physics, University of Wollongong [Australia], Geant4 Associates International (G4AI), Ecoanalytica, Institut de Neurosciences cognitives et intégratives d'Aquitaine (INCIA), Université Bordeaux Segalen - Bordeaux 2-Université Sciences et Technologies - Bordeaux 1-SFR Bordeaux Neurosciences-Centre National de la Recherche Scientifique (CNRS), Proton Therapy Center, National Cancer Center Korea, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), KEK (High energy accelerator research organization), European Space Research and Technology Centre (ESTEC), European Space Agency (ESA), Vinča Institute of Nuclear Sciences, University of Belgrade [Belgrade], Ton Duc Thang University [Hô-Chi-Minh-City], Université Sciences et Technologies - Bordeaux 1 (UB)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM), Universidade Estadual de Campinas = University of Campinas (UNICAMP), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Bordeaux Segalen - Bordeaux 2-Université Sciences et Technologies - Bordeaux 1 (UB)-SFR Bordeaux Neurosciences-Centre National de la Recherche Scientifique (CNRS), and Agence Spatiale Européenne = European Space Agency (ESA)

Subjects
Nuclear and High Energy Physics, Work (thermodynamics), Radiation transport, Physics::Medical Physics, Reference data (financial markets), Monte Carlo method, Ion, Deposition (phase transition), Statistical physics, Instrumentation, Monte Carlo, Physics, Energy depositions, [PHYS]Physics [physics], Geant4-DNA, Ion track, Geant4 dnas, Monte Carlo methods, Liquids, DNA, Analytical calculation, Monte- carlo simulations, Charged particle, Computational physics, Comparative studies, Liquid water, Dose, Dynamic Monte Carlo method
Abstract

International audience; An accurate modeling of radial energy deposition around ion tracks is a key requirement of radiation transport software used for simulations in radiobiology at the sub-cellular scale. The work presented in this paper is part of the on-going benchmarking of the "Geant4-DNA" physics processes and models, which are available in the Geant4 Monte Carlo simulation toolkit for the low energy transport of particles in liquid water. We present for the first time radial dose distributions of incident ion tracks simulated with "Geant4-DNA". Simulation results are compared to other results available in the literature, obtained from analytical calculations, step-by-step Monte Carlo simulations and measurements. They show a reasonable agreement with reference data. © 2014 Elsevier B.V. All rights reserved.

Published
2014
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19. Chants d'Auvergne

Author

T., J., primary, Canteloube, J., additional, Stepan, Vaclav, additional, and Tolstoi, S. L., additional

Published
1928
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