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47 results on '"Steinmeyer, Brian"'

20. Omega-3 augmentation of sertraline in treatment of depression in patients with coronary heart disease

Author

Carney, Robert M., Freedland, Kenneth E., Rubin, Eugene H., Rich, Michael W., Steinmeyer, Brian C., and Harris, William S.

Subjects
Coronary heart disease -- Care and treatment, Depression, Mental -- Care and treatment, Omega-3 fatty acids -- Usage, Omega-3 fatty acids -- Health aspects, Psychiatric patients -- Health aspects, Sertraline -- Usage, Sertraline -- Health aspects
Abstract

A study was conducted to evaluate whether the use of omega-3 helped improve the response to sertraline in the case of patients suffering from depression and coronary heart disease. Results indicated that there were no benefits encountered from the use of omega-3.

Published
2009

21. Treatment of depression after coronary artery bypass surgery: a randomized controlled trial

Author

Freedland, Kenneth E., Skala, Judith A., Carney, Robert M., Rubin, Eugene H., Lustman, Patrick J., Davila-Roman, Victor G., Steinmeyer, Brian C., and Hogue, Charles W., Jr.

Subjects
Depression, Mental -- Care and treatment, Coronary artery bypass -- Complications and side effects, Coronary artery bypass -- Psychological aspects, Cognitive therapy -- Usage, Cognitive therapy -- Health aspects, Stress management -- Usage, Stress management -- Health aspects, Health, Psychology and mental health
Published
2009

28. Depression and Multiple Rehospitalizations in Patients with Heart Failure

Author

Freedland, Kenneth E., Carney, Robert M., Rich, Michael W., Steinmeyer, Brian C., Skala, Judith A., and Dávila-Román, Victor G.

Subjects
Adult, Heart Failure, Male, Psychiatric Status Rating Scales, Time Factors, Depression, Middle Aged, Prognosis, Patient Readmission, Risk Assessment, Severity of Illness Index, Article, Risk Factors, Linear Models, Odds Ratio, Humans, Female, Aged, Proportional Hazards Models
Abstract

There have been few studies of the effect of depression on rehospitalization in patients with heart failure (HF), and even fewer on its role in multiple rehospitalizations.Depression is an independent risk factor for multiple readmissions in patients with HF.A cohort of 662 patients with HF who were discharged alive after hospitalization were interviewed to evaluate symptoms of depression and were followed for 1 year. All-cause readmissions were documented by chart review. A marginal proportional rates model was used to model the effect of depression on the rate of rehospitalization with adjustment for known predictors of HF outcomes.Depression symptoms predicted multiple readmissions (adjusted hazard ratio [HR]: 1.08, 95% confidence interval [CI]: 1.03-1.13, P = 0.0008). Compared with patients without depression, those who met the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria for major depression at index were at the highest risk for multiple rehospitalizations (HR: 1.51, 95% CI: 1.15-1.97, P = 0.003).Depression is an independent risk factor for multiple all-cause readmissions in patients with HF.

Published
2016

41. Nighttime Heart Rate and Survival in Depressed Patients Post Acute Myocardial Infarction

Author

Carney, Robert M., primary, Steinmeyer, Brian, additional, Freedland, Kenneth E., additional, Blumenthal, James A., additional, Stein, Phyllis K., additional, Steinhoff, William A., additional, Howells, William B., additional, Berkman, Lisa F., additional, Watkins, Lana L., additional, Czajkowski, Susan M., additional, Domitrovich, Peter P., additional, Burg, Matthew M., additional, Hayano, Junichiro, additional, and Jaffe, Allan S., additional

Published
2008
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43. Heart Rate Turbulence, Depression, and Survival After Acute Myocardial Infarction

Author

Carney, Robert M., primary, Howells, William B., additional, Blumenthal, James A., additional, Freedland, Kenneth E., additional, Stein, Phyllis K., additional, Berkman, Lisa F., additional, Watkins, Lana L., additional, Czajkowski, Susan M., additional, Steinmeyer, Brian, additional, Hayano, Junichiro, additional, Domitrovich, Peter P., additional, Burg, Matthew M., additional, and Jaffe, Allan S., additional

Published
2007
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44. Obstructive Sleep Apnea/Hypopnea Syndrome and Poor Response to Sertraline in Patients With Coronary Heart Disease.

Author

Roest, Annelieke M., Carney, Robert M., Stein, Phyllis K., Freedland, Kenneth E., Meyer, Hilary, Steinmeyer, Brian C., de Jonge, Peter, and Rubin, Eugene H.

Subjects
ANTIDEPRESSANTS, CORONARY disease, SLEEP apnea syndromes, SERTRALINE, MENTAL depression
Abstract

The article discusses a study to determine the link between obstructive sleep apnea/hypopnea syndrome (OSAHS) and the poor response to sertraline in patients with coronary heart disease. OSAHS refers to a chronic, sleep-related breathing disorder characterized by recurrent complete blockage or partial blockage of the upper airway. The results showed that OSAHS is associated with a relatively poor response to antidepressant medication.

Published
2012
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45. Omega-3 Fatty Acids for CHD With Depression.

Author

Anghelescu, Ion, Carney, Robert M., Freedland, Kenneth E., and Steinmeyer, Brian C.

Subjects
LETTERS to the editor, CORONARY disease, OMEGA-3 fatty acids, SERTRALINE, ANTIDEPRESSANTS
Abstract

A letter to the editor is presented in response to the article "Omega-3 augmentation of sertraline in treatment of depression in patients with coronary heart disease," by Robert M. Carney et al, as well as a response by article's authors.

Published
2010
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46. Psychosocial Syndemics and Multimorbidity in Patients with Heart Failure † .

Author

Freedland KE, Skala JA, Carney RM, Steinmeyer BC, and Rich MW

Abstract

Heart failure (HF) is a common cause of hospitalization and mortality in older adults. HF is almost always embedded within a larger pattern of multimorbidity, yet many studies exclude patients with complex psychiatric and medical comorbidities or cognitive impairment. This has left significant gaps in research on the problems and treatment of patients with HF. In addition, HF is only one of multiple challenges facing patients with multimorbidity, stressful socioeconomic circumstances, and psychosocial problems. The purpose of this study is to identify combinations of comorbidities and health disparities that may affect HF outcomes and require different mixtures of medical, psychological, and social services to address. The syndemics framework has yielded important insights into other disorders such as HIV/AIDS, but it has not been applied to the complex psychosocial problems of patients with HF. The multimorbidity framework is an alternative approach for investigating the effects of multiple comorbidities on health outcomes. The specific aims are: (1) to determine the coprevalence of psychiatric and medical comorbidities in patients with HF ( n = 535); (2) to determine whether coprevalent comorbidities have synergistic effects on readmissions, mortality, self-care, and global health; (3) to identify vulnerable subpopulations of patients with HF who have high coprevalences of syndemic comorbidities; (4) to determine the extent to which syndemic comorbidities explain adverse HF outcomes in vulnerable subgroups of patients with HF; and (5) to determine the effects of multimorbidity on readmissions, mortality, self-care, and global health., Competing Interests: CONFLICTS OF INTEREST The authors declare that they have no conflicts of interest.

Published
2021
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47. Increased ventricular premature contraction frequency during rem sleep in patients with coronary artery disease and obstructive sleep apnea.

Author

Watanabe MA, Bhalodia R, Lundequam EJ, Domitrovich PP, Steinmeyer BC, Stein PK, Freedland KE, Duntley SP, and Carney RM

Abstract

Background: Patients with obstructive sleep apnea are reported to have a peak of sudden cardiac death at night, in contrast to patients without apnea whose peak is in the morning. We hypothesized that ventricular premature contraction (VPC) frequency would correlate with measures of apnea and sympathetic activity., Methods: Electrocardiograms from a sleep study of 125 patients with coronary artery disease were evaluated. Patients were categorized by apnea-hypopnea index (AHI) into Moderate (AHI <15) or Severe (AHI>15) apnea groups. Sleep stages studied were Wake, S1, S2, S34, and rapid eye movement (REM). Parameters of a potent autonomically-based risk predictor for sudden cardiac death called heart rate turbulence were calculated., Results: There were 74 Moderate and 51 Severe obstructive sleep apnea patients. VPC frequency was affected significantly by sleep stage (Wake, S2 and REM, F=5.8, p<.005) and by AHI (F=8.7, p<.005). In Severe apnea patients, VPC frequency was higher in REM than in Wake (p=.011). In contrast, patients with Moderate apnea had fewer VPCs and exhibited no sleep stage dependence (p=.19). Oxygen desaturation duration per apnea episode correlated positively with AHI (r(2)=.71, p<.0001), and was longer in REM than in non-REM (p<.0001). The heart rate turbulence parameter TS correlated negatively with oxygen desaturation duration in REM (r(2)=.06, p=.014)., Conclusions: Higher VPC frequency coupled with higher sympathetic activity caused by longer apnea episodes in REM sleep may be one reason for increased nocturnal death in apneic patients.

Published
2008

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