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1. Targeted temperature control following traumatic brain injury: ESICM/NACCS best practice consensus recommendations

Author

Lavinio, Andrea, Coles, Jonathan P., Robba, Chiara, Aries, Marcel, Bouzat, Pierre, Chean, Dara, Frisvold, Shirin, Galarza, Laura, Helbok, Raimund, Hermanides, Jeroen, van der Jagt, Mathieu, Menon, David K., Meyfroidt, Geert, Payen, Jean-Francois, Poole, Daniele, Rasulo, Frank, Rhodes, Jonathan, Sidlow, Emily, Steiner, Luzius A., Taccone, Fabio Silvio, and Takala, Riikka

Published
2024
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2. Association of preoperative beta-blocker use and cardiac complications after major noncardiac surgery: a prospective cohort study

Author

Mueller, Philip, Burri, Katrin, Weder, Samantha, Skolozubova, Daria, Horvat-Csoti, Sonja, Doebele, Niklas, Schaer, Marco, Heimbach, Bent, Lopez-Ayala, Pedro, Seeberger, Esther, Doyle, Nadine, Meissner, Kathrin, Glarner, Noemi, Puelacher, Christian, Gualandro, Danielle M., Pargger, Mirjam, Huré, Gabrielle, Maiorano, Silvia, Strebel, Ivo, Fried, Simona, Bolliger, Daniel, Steiner, Luzius A., Lampart, Andreas, Lurati Buse, Giovanna, Mujagic, Edin, Lardinois, Didier, Kindler, Christoph, Guerke, Lorenz, Schaeren, Stefan, Mueller, Andreas, Clauss, Martin, Buser, Andreas, Hammerer-Lercher, Angelika, and Mueller, Christian

Published
2024
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5. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author

Hemmes, Sabrine NT., Gama de Abreu, Marcelo, Severgnini, Paolo, Hollmann, Markus W., Binnekade, Jan M., Wrigge, Hermann, Canet, Jaume, Hiesmayr, Michael, Schmid, Werner, Tschernko, Edda, Jaber, Samir, Hedenstierna, Göran, Putensen, Christian, Pelosi, Paolo, Schultz, Marcus J., Marti, Agnes, Bacuzzi, Alessandro, Brodhun, Alexander, Molin, Alexandre, Merten, Alfred, Parera, Ana, Brunelli, Andrea, Cortegiani, Andrea, Güldner, Andreas, Reske, Andreas W., Gratarola, Angelo, Giarratano, Antonino, Bastin, Bea, Heyse, Bjorn, Mazul-Sunko, Branka, Amantea, Bruno, Barberis, Bruno, Uhlig, Christopher, Marín, Conrado Minguez, Celentano, Cristian, La Bella, Daniela, D’Antini, David, Velghe, David, Sulemanji, Demet, De Robertis, Edoardo, Hartmann, Eric, Montalto, Francesca, Tropea, Francesco, Mills, Gary H., Cinnella, Gilda, Della Rocca, Giorgio, Caggianelli, Girolamo, Pellerano, Giulia, Mollica, Giuseppina, Bugedo, Guillermo, Mulier, Jan-Paul, Vandenbrande, Jeroen, Geib, Johann, Yaqub, Jonathan, Florez, Jorge, Mayoral, Juan F., Sprung, Juraj, Van Limmen, Jurgen, Bos, Lieuwe DJ., de Baerdemaeker, Luc, Jamaer, Luc, Spagnolo, Luigi, Strys, Lydia, Gil, Manuel Granell, Vidal Melo, Marcos F., Unzueta, Maria Carmen, Moral, Maria Victoria, Ferner, Marion, Weiss, Martin, Vanoni, Massimo, Schaefer, Maximilian S., Prieto, Mercè, Grio, Michele, Spieth, Peter Markus, Simon, Philipp, Bodger, Phoebe, Sierra, Pilar, Laufenberg-Feldmann, Rita, Rusca, Roberta, Proietti, Rodolfo, Raineri, Santi Maurizio, Caroleo, Santo, Sabaté, Sergi, De Hert, Stefan, Pezzato, Stefano, Treschan, Tanja A., Goranovic, Tatjana, Koch, Thea, Bluth, Thomas, Kiss, Thomas, Perilli, Valter, Cegarra, Virginia, Ferrando, Carlos, Belda, Javier, Soro, Marina, Unzueta, Carmen, Suarez-Sipmann, Fernando, Librero, Julián, Llombart, Alicia, Rovira, Lucas, Granell, Manuel, Aldecoa, César, Diaz-Cambronero, Oscar, Balust, Jaume, Garutti, Ignacio, Gonzalez, Rafael, Gallego, Lucia, Garcia del Valle, Santiago, Redondo, Javier, Pestaña, David, Rodríguez, Aurelio, García, Javier, Matta, Manuel de la, Ibáñez, Maite, Barrios, Francisco, Hernández, Samuel, Torres, Vicente, Peiró, Salvador, Pozo, Natividad, Villena, Abigail, Carramiñana, Albert, Gallego-Casilda, Alberto, Duca, Alejandro, Alcón, Amalia, Miñana, Amanda, Asensio, Ana, Colás, Ana, Galve, Ana Isabel, Izquierdo, Ana, Jurado, Ana, Pérez, Ana María, Mugarra, Ana, Gutierrez, Andrea, De Miguel, Ángeles, Lozano, Angels, Katime, Antonio, Romero, Antonio, Garrigues, Beatriz, Ayas, Begoña, Arocas, Blanca, Delgado, Carlos, Fernández, Carmen, Romero, Carolina, Gallego, Clara, Garcés, Cristina, Lisbona, Cristina, Parrilla, Cristina, López-Herrera, Daniel, González, Domingo, Llamazares, Eduardo, Del Rio, Elena, Lozano, Elena, Pastor, Ernesto, Chamorro, Estefanía, Gracia, Estefanía, Sánchez, Ester, Romero, Esther, Díez, Fernando, Serralta, Ferran, Daviu, Francisco, Sandín, Francisco, Aguilar, Gerardo, Tusman, Gerardo, Azparren, Gonzalo, Martínez-Pallí, Graciela, Mazzinari, Guido, Benítez, Inmaculada, Hernandéz, Inmaculada, India, Inmaculada, León, Irene, Fuentes, Isabel, Ruiz, Isabel, Puig, Jaume, Román, Javie Ignacio, Acosta, Jesús, Rico-Feijoo, Jesús, Olmedo, Jonathan, Carbonell, Jose A., Alonso, Jose M., Pérez, Jose María, Marcos, Jose Miguel, Navarro, Jose, Valdivia, Jose, Carrizo, Juan, Piqueras, Laura, Soriano, Laura, Vaquero, Laura, Miguel, Lisset, Muñoz, Lorena, Valencia, Lucia, Olmedilla, Luis, Etulain, Mᵃ Justina, Tisner, Manuel, Barrio, María, Alonso, María Dolores, García, María, Hernández, María J., Alberola, María José, Parra, María, Argente, María Pilar, Vila, María, De Fez, Mario, Agilaga, Marta, Gine, Marta, Ayuso, Mercedes, García, Mercedes, Bejarano, Natalia, Peña, Natalia, Ojeda, Nazario, Martínez, Nilda, García, Nuria, Padrón, Oto, García, Pablo, Valls, Paola, Cruz, Patricia, Piñeiro, Patricia, Charco, Pedro, Anaya, Rafael, López, Ramiro, Rodríguez, Rayco, Martínez, Rocío, Pujol, Roger, Dosdá, Rosa, Lardies, Rosa, Díaz, Ruben, Villazala, Rubén, Zapatero, Sara, Cabrera, Sergio, Sánchez, Sergio, Martin, Silvia, Diaz, Suzana, Franco, Tania, Moreno, Tania, Socorro, Tania, Gilabert, Vicente, Balandrón, Victor, Moral, Victoria, Cegarra, Virgina, Varón, Viviana, Abelha, Fernando, Abitağaoğlu, Sühayla, Achilles, Marc, Adebesin, Afeez, Adriaensens, Ine, Ahene, Charles, Akbar, Fatima, Al Harbi, Mohammed, Al Khoury al Kallab, Rita, Albanel, Xavier, Aldenkortt, Florence, Saleh Alfouzan, Rawan Abdullah, Alruqaie, Reef, Altermatt, Fernando, Luís de Castro Araujo, Bruno, Arbesú, Genaro, Artsi, Hanna, Aurilio, Caterina, Ayanoglu, Omer Hilmi, Baig, Harris, Baird, Yolanda, Balonov, Konstantin, Banks, Samantha, Bao, Xiaodong, Baumgartner, Mélanie, Tortosa, Isabel Belda, Bergamaschi, Alice, Bergmann, Lars, Bigatello, Luca, Pérez, Elena Biosca, Birr, Katja, Bojaxhi, Elird, Bonenti, Chiara, Bonney, Iwona, Bos, Elke M.E., Bowman, Sara, Braz, Leandro Gobbo, Brugnoni, Elisa, Brull, Sorin J., Brunetti, Iole, Bruni, Andrea, Buenvenida, Shonie L., Busch, Cornelius Johannes, Camerini, Giovanni, Capatti, Beatrice, Carmona, Javiera, Carungcong, Jaime, Carvalho, Marta, Cattan, Anat, Cavaleiro, Carla, Chiumello, Davide, Ciardo, Stefano, Coburn, Mark, Colella, Umberto, Contreras, Victor, Dincer, Pelin Corman, Cotter, Elizabeth, Crovetto, Marcia, Darrah, William, Davies, Simon, Del Cojo Peces, Enrique, Delphin, Ellise, Diaper, John, Junior, Paulo do Nascimento, Donatiello, Valerio, Dong, Jing, Dourado, Maria do Socorro, Dullenkopf, Alexander, Ebner, Felix, Elgendy, Hamed, Ellenberger, Christoph, Arı, Dilek Erdoğan, Ermert, Thomas, Farah, Fadi, Fernandez-Bustamante, Ana, Ferreira, Cristina, Fiore, Marco, Fonte, Ana, Palahí, Christina Fortià, Galimberti, Andrea, Garofano, Najia, Giaccari, Luca Gregorio, Gilsanz, Fernando, Girrbach, Felix, Gobbi, Luca, Godfried, Marc Bernard, Goettel, Nicolai, Goldstein, Peter A., Goren, Or, Gorlin, Andrew, Graterol, Juan, Guyon, Pierre, Haire, Kevin, Harou, Philippe, Helf, Antonia, Hemmes, Sabrine N.T., Hempel, Gunther, Hernández Cádiz, María José, Heyse, Björn, Huercio, Ivan, Ilievska, Jasmina, Jakus, Lien, Jeganath, Vijay, Jelting, Yvonne, Jung, Minoa, Kabon, Barbara, Kacha, Aalok, Ilić, Maja Karaman, Karuppiah, Arunthevaraja, Kavas, Ayse Duygu, Barcelos, Gleicy Keli, Kellogg, Todd A., Kemper, Johann, Kerbrat, Romain, Khodr, Suraya, Kienbaum, Peter, Kir, Bunyamin, Kivrak, Selin, Klarić, Vlasta, Köksal, Ceren, Kowark, Ana, Kranke, Peter, Kuvaki, Bahar, Kuzmanovska, Biljana, Laffey, John, Lange, Mirko, Freitas de Lemos, Marília, Licker, Marc-Joseph, López-Baamonde, Manuel, López-Hernández, Antonio, Lopez-Martinez, Mercedes, Luise, Stéphane, MacGregor, Mark, Magalhães, Danielle, Maillard, Julien, Malerbi, Patrizia, Manimekalai, Natesan, Margarson, Michael, Markstaller, Klaus, Martin, Archer K., Martin, David P., Martin, Yvette N., Martínez-Ocon, Julia, Martin-Loeches, Ignacio, Maseda, Emilio, Matot, Idit, McAuliffe, Niamh, McKenzie, Travis J., Medina, Paulina, Meersch, Melanie, Menzen, Angelika, Mertens, Els, Meurer, Bernd, Meyer-Treschan, Tanja, Miao, Changhong, Micalizzi, Camilla, Milić, Morena, Pinheiro Módolo, Norma Sueli, Moine, Pierre, Mölders, Patrick, Montero-Feijoo, Ana, Moret, Enrique, Muller, Markus K., Murphy, Zoe, Nalwaya, Pramod, Naumovski, Filip, Navalesi, Paolo, Navarro e Lima, Lais Helena, Adam, Višnja Nesek, Neumann, Claudia, Newell, Christopher, Nisnevitch, Zoulfira, Nizamuddin, Junaid, Novazzi, Cecilia, O'Connor, Michael, Oprea, Günther, Sungur, Mukadder Orhan, Özbilgin, Şule, Pace, Maria Caterina, Pacheco, Marcos, Packianathaswamy, Balaji, Gonzalez, Estefania Palma, Papaspyros, Fotios, Paredes, Sebastián, Passavanti, Maria Beatrice, Pedemonte, Juan Cristobal, Peremin, Sanja, Philipsenburg, Christoph, Pinho, Daniela, Pinho, Silvia, Posthuma, Linda M., Pota, Vincenzo, Preckel, Benedikt, Priani, Paolo, Rached, Mohamed Aymen, Radoeshki, Aleksandar, Ragazzi, Riccardo, Rajamanickam, Tamilselvan, Rajamohan, Arthi, Ramakrishna, Harish, Rangarajan, Desikan, Reiterer, Christian, Renew, J. Ross, Reynaud, Thomas, Rhys, Rhidian, Rivas, Eva, Robitzky, Luisa, Rossaint, Rolf, Rubulotta, Francesca, Machado, Humberto S., Nunes, Catarina S., Sabbatini, Giovanni, Samuels, Jon D., Sanahuja, Josep Martí, Sansone, Pasquale, Santos, Alice, Sayedalahl, Mohamed, Scharffenberg, Martin, Schiffer, Eduardo, Schliewe, Nadja, Schorer, Raoul, Schumann, Roman, Selmo, Gabriele, Sendra, Mar, Senturk, Mert, Shaw, Kate, Shosholcheva, Mirjana, Sibai, Abdulrazak, Simonassi, Francesca, Sinno, Claudia, Sivrikoz, Nukhet, Skandalou, Vasiliki, Smith, Neil, Soares, Maria, Artiles, Tania Socorro, Castro, Diogo Sousa, Sousa, Miguel, Spadaro, Savino, Stamatakis, Emmanouil, Steiner, Luzius A., Stevenazzi, Andrea, Suarez-de-la-Rica, Alejandro, Suppan, Mélanie, Teichmann, Robert, Tena Guerrero, José Maria, Thiel, Bram, Tolós, Raquel, Altun, Gulbin Tore, Tucci, Michelle, Turnbull, Zachary A., Turudić, Žana, Unterberg, Matthias, Van Nieuwenhove, Yves, Van Waesberghe, Julia, Vidal Melo, Marcos Francisco, Vitković, Bibiana, Vivona, Luigi, Vizcaychipi, Marcela, Volta, Carlo Alberto, Weber, Anne, Weingarten, Toby N., Wittenstein, Jakob, Wyffels, Piet, Yagüe, Julio, Yates, David, Yavru, Ayşen, Zac, Lilach, Zhong, Jing, Campos, Niklas S., Librero, Julian, Ball, Lorenzo, and Serpa Neto, A.

Published
2022
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6. Cardiovascular imaging following perioperative myocardial infarction/injury

Author

Arslani, Ketina, Gualandro, Danielle M., Puelacher, Christian, Lurati Buse, Giovanna, Lampart, Andreas, Bolliger, Daniel, Schulthess, David, Glarner, Noemi, Hidvegi, Reka, Kindler, Christoph, Blum, Steffen, Cardozo, Francisco A. M., Caramelli, Bruno, Gürke, Lorenz, Wolff, Thomas, Mujagic, Edin, Schaeren, Stefan, Rikli, Daniel, Campos, Carlos A., Fahrni, Gregor, Kaufmann, Beat A., Haaf, Philip, Zellweger, Michael J., Kaiser, Christoph, Osswald, Stefan, Steiner, Luzius A., and Mueller, Christian

Published
2022
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7. Patient- and procedure-related factors in the pathophysiology of perioperative myocardial infarction/injury

Author

Badertscher, Patrick, Boeddinghaus, Jasper, Buser, Andreas, Freese, Michael, Hammerer-Lercher, Angelika, Koechlin, Luca, Lopez-Ayala, Pedro, Mehrkens, Arne, Mujagic, Edin, Nestelberger, Thomas, Prepoudis, Alexandra, Mitrovic, Sandra, Rentsch, Katharina, Seeberger, Esther, Vogt, Ronja, Walter, Joan, Wildi, Karin, Wolff, Thomas, Wussler, Desiree, Gueckel, Johanna, Puelacher, Christian, Glarner, Noemi, Gualandro, Danielle M., Strebel, Ivo, Zimmermann, Tobias, Arslani, Ketina, Hidvegi, Reka, Liffert, Marcel, Genini, Alessandro, Marbot, Stella, Schlaepfer, Maria, Steiner, Luzius A., Bolliger, Daniel, Lampart, Andreas, Gürke, Lorenz, Kindler, Christoph, Schären, Stefan, Osswald, Stefan, Clauss, Martin, Rikli, Daniel, Lurati Buse, Giovanna, and Mueller, Christian

Published
2022
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8. Wireless wearables for postoperative surveillance on surgical wards: a survey of 1158 anaesthesiologists in Western Europe and the USA

Author

Biais, Matthieu, Bonhomme, Vincent, Buhre, Wolfgang, Cholley, Bernard, Constantin, Jean-Michel, Futier, Emmanuel, Jaber, Samir, Leone, Marc, Preckel, Benedikt, Reuter, Daniel, Schoettker, Patrick, Scheeren, Thomas, Sander, Michael, Steiner, Luzius A., Treskatsch, Sascha, Zacharowski, Kai, Afonso, Anoushka, Arora, Lovkesh, Ault, Michael L., Bartels, Karsten, Brown, Charles, Brown, Daniel, Colquhoun, Douglas, Fink, Ryan, Gan, Tong J., Hanson, Neil, Hyder, Omar, Miller, Timothy, McEvoy, Matt, Pearl, Ronald, Pirracchio, Romain, Popovich, Marc, Satyapriya, Sree, Segal, B. Scott, Williams, George, Michard, Frederic, Thiele, Robert H., Saugel, Bernd, Joosten, Alexandre, Flick, Moritz, and Khanna, Ashish K.

Published
2022
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9. The number of comorbidities as an important cofactor to ASA class in predicting postoperative outcome: An international multicentre cohort study.

Author

Grob, Christian A., Angehrn, Luzius W., Kaufmann, Mark, Hahnloser, Dieter, Winiker, Michael, Erb, Thomas O., Joller, Sonja, Schumacher, Philippe, Bruppacher, Heinz R., O'Grady, Gregory, Murtagh, Jonathon, Gawria, Larsa, Albers, Kim, Meier, Sonja, Heilbronner Samuel, Anna R., Schindler, Christian, Steiner, Luzius A., and Dell‐Kuster, Salome

Subjects
ELECTRONIC health records, LENGTH of stay in hospitals, SURGICAL complications, TREATMENT effectiveness, POPULATION aging
Abstract

Background: Multimorbidity is a growing burden in our ageing society and is associated with perioperative morbidity and mortality. Despite several modifications to the ASA physical status classification, multimorbidity as such is still not considered. Thus, the aim of this study was to quantify the burden of comorbidities in perioperative patients and to assess, independent of ASA class, its potential influence on perioperative outcome. Methods: In a subpopulation of the prospective ClassIntra® validation study from eight international centres, type and severity of anaesthesia‐relevant comorbidities were additionally extracted from electronic medical records for the current study. Patients from the validation study were of all ages, undergoing any type of in‐hospital surgery and were followed up until 30 days postoperatively to assess perioperative outcomes. Primary endpoint was the number of comorbidities across ASA classes. The associated postoperative length of hospital stay (pLOS) and Comprehensive Complication Index (CCI®) were secondary endpoints. On a scale from 0 (no complication) to 100 (death) the CCI® measures the severity of postoperative morbidity as a weighted sum of all postoperative complications. Results: Of 1421 enrolled patients, the mean number of comorbidities significantly increased from 1.5 in ASA I (95% CI, 1.1–1.9) to 10.5 in ASA IV (95% CI, 8.3–12.7) patients. Furthermore, independent of ASA class, postoperative complications measured by the CCI® increased per each comorbidity by 0.81 (95% CI, 0.40–1.23) and so did pLOS (geometric mean ratio, 1.03; 95% CI, 1.01–1.06). Conclusions: These data quantify the high prevalence of multimorbidity in the surgical population and show that the number of comorbidities is predictive of negative postoperative outcomes, independent of ASA class. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Association of preoperative beta-blocker use and cardiac complications after major noncardiac surgery: a prospective cohort study

Author

Glarner, Noemi, primary, Puelacher, Christian, additional, Gualandro, Danielle M., additional, Pargger, Mirjam, additional, Huré, Gabrielle, additional, Maiorano, Silvia, additional, Strebel, Ivo, additional, Fried, Simona, additional, Bolliger, Daniel, additional, Steiner, Luzius A., additional, Lampart, Andreas, additional, Lurati Buse, Giovanna, additional, Mujagic, Edin, additional, Lardinois, Didier, additional, Kindler, Christoph, additional, Guerke, Lorenz, additional, Schaeren, Stefan, additional, Mueller, Andreas, additional, Clauss, Martin, additional, Buser, Andreas, additional, Hammerer-Lercher, Angelika, additional, Mueller, Christian, additional, Mueller, Philip, additional, Burri, Katrin, additional, Weder, Samantha, additional, Skolozubova, Daria, additional, Horvat-Csoti, Sonja, additional, Doebele, Niklas, additional, Schaer, Marco, additional, Heimbach, Bent, additional, Lopez-Ayala, Pedro, additional, Seeberger, Esther, additional, Doyle, Nadine, additional, and Meissner, Kathrin, additional

Published
2024
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12. Targeted Temperature Management following Traumatic Brain Injury: ESICM / NACCS Consensus Recommendations Guidelines

Author

Lavinio, Andrea, primary, Coles, Jonathan P, additional, Robba, Chiara, additional, Aries, Marcel, additional, Bouzat, Pierre, additional, Chean, Dara, additional, Frisvold, Shirin, additional, Galarza, Laura, additional, Helbok, Raimund, additional, Hermanides, Jeroen, additional, Jagt, Mathieu van der, additional, Menon, David K, additional, Meyfroidt, Geert, additional, Payen, Jean-Francois, additional, Poole, Daniele, additional, Rasulo, Frank, additional, Rhodes, Jonathan, additional, Sidlow, Emily, additional, Steiner, Luzius A, additional, Taccone, Fabio S, additional, and Takala, Riikka, additional

Published
2024
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14. Prospective validation of classification of intraoperative adverse events (ClassIntra) : international, multicentre cohort study

Author

Dell-Kuster, Salome, Gomes, Nuno V, Gawria, Larsa, Aghlmandi, Soheila, Aduse-Poku, Maame, Bissett, Ian, Blanc, Catherine, Brandt, Christian, ten Broek, Richard B, Bruppacher, Heinz R, Clancy, Cillian, Delrio, Paolo, Espin, Eloy, Galanos-Demiris, Konstantinos, Gecim, Ethem, Ghaffari, Shahbaz, Gié, Olivier, Goebel, Barbara, Hahnloser, Dieter, Herbst, Friedrich, Orestis, Ioannidis, Joller, Sonja, Kang, Soojin, Martín, Rocio, Mayr, Johannes, Meier, Sonja, Murugesan, Jothi, Nally, Deirdre, Ozcelik, Menekse, Pace, Ugo, Passeri, Michael, Rabanser, Simone, Ranter, Barbara, Rega, Daniela, Ridgway, Paul F, Rosman, Camiel, Schmid, Roger, Schumacher, Philippe, Solis-Pena, Alejandro, Villarino, Laura, Vrochides, Dionisios, Engel, Alexander, O’Grady, Greg, Loveday, Benjamin, Steiner, Luzius A, Van Goor, Harry, Bucher, Heiner C, Clavien, Pierre-Alain, Kirchhoff, Philipp, and Rosenthal, Rachel

Published
2020

15. Adherence to the European Society of Cardiology/European Society of Anaesthesiology recommendations on preoperative cardiac testing and association with positive results and cardiac events: a cohort study

Author

Gueckel, Johanna, Strebel, Ivo, Liffert, Marcel, du Fay de Lavallaz, Jeanne, Pouly, Jeanne, Hammerer-Lercher, Angelika, Rentsch, Katharina, Lopez Ayala, Pedro, Osswald, Stefan, Seeberger, Esther, Koechlin, Luca, Buser, Andreas, Rikli, Daniel, Schaeren, Stefan, Lardinois, Didier, Caramelli, Bruno, Lurati Buse, Giovanna A.L., Puelacher, Christian, Gualandro, Danielle Menosi, Kilinc, Derya, Glarner, Noemi, Hidvegi, Reka, Bolliger, Daniel, Arslani, Ketina, Lampart, Andreas, Steiner, Luzius A., Kindler, Christoph, Wolff, Thomas, Mujagic, Edin, Guerke, Lorenz, and Mueller, Christian

Published
2021
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16. Association between self-reported functional capacity and major adverse cardiac events in patients at elevated risk undergoing noncardiac surgery: a prospective diagnostic cohort study

Author

Gueckel, Johanna, Strebel, Ivo, Liffert, Marcel, Wolff, Thomas, EdinMujagic, Guerke, Lorenz, Hammerer-Lercher, Angelika, Rentsch, Katharina, Boeddinghaus, Jasper, Nestelberger, Thomas, Wildi, Karin, Zimmermann, Tobias, Prepoudis, Alexandra, Lampart, Andreas, Osswald, Stefan, Seeberger, Esther, Koechlin, Luca, Buser, Andreas, Rikli, Daniel, Lurati Buse, Giovanna A.L., Puelacher, Christian, Gualandro, Danielle Menosi, Genini, Alessandro S., Hidvegi, Reka, Bolliger, Daniel, Arslani, Ketina, Steiner, Luzius A., Kindler, Christoph, and Mueller, Christian

Published
2021
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17. Targeted temperature control following traumatic brain injury:ESICM/NACCS best practice consensus recommendations

Author

Lavinio, Andrea, Coles, Jonathan P., Robba, Chiara, Aries, Marcel, Bouzat, Pierre, Chean, Dara, Frisvold, Shirin, Galarza, Laura, Helbok, Raimund, Hermanides, Jeroen, van der Jagt, Mathieu, Menon, David K., Meyfroidt, Geert, Payen, Jean Francois, Poole, Daniele, Rasulo, Frank, Rhodes, Jonathan, Sidlow, Emily, Steiner, Luzius A., Taccone, Fabio Silvio, Takala, Riikka, Lavinio, Andrea, Coles, Jonathan P., Robba, Chiara, Aries, Marcel, Bouzat, Pierre, Chean, Dara, Frisvold, Shirin, Galarza, Laura, Helbok, Raimund, Hermanides, Jeroen, van der Jagt, Mathieu, Menon, David K., Meyfroidt, Geert, Payen, Jean Francois, Poole, Daniele, Rasulo, Frank, Rhodes, Jonathan, Sidlow, Emily, Steiner, Luzius A., Taccone, Fabio Silvio, and Takala, Riikka

Abstract

Aims and scope: The aim of this panel was to develop consensus recommendations on targeted temperature control (TTC) in patients with severe traumatic brain injury (TBI) and in patients with moderate TBI who deteriorate and require admission to the intensive care unit for intracranial pressure (ICP) management. Methods: A group of 18 international neuro-intensive care experts in the acute management of TBI participated in a modified Delphi process. An online anonymised survey based on a systematic literature review was completed ahead of the meeting, before the group convened to explore the level of consensus on TTC following TBI. Outputs from the meeting were combined into a further anonymous online survey round to finalise recommendations. Thresholds of ≥ 16 out of 18 panel members in agreement (≥ 88%) for strong consensus and ≥ 14 out of 18 (≥ 78%) for moderate consensus were prospectively set for all statements. Results: Strong consensus was reached on TTC being essential for high-quality TBI care. It was recommended that temperature should be monitored continuously, and that fever should be promptly identified and managed in patients perceived to be at risk of secondary brain injury. Controlled normothermia (36.0–37.5 °C) was strongly recommended as a therapeutic option to be considered in tier 1 and 2 of the Seattle International Severe Traumatic Brain Injury Consensus Conference ICP management protocol. Temperature control targets should be individualised based on the perceived risk of secondary brain injury and fever aetiology. Conclusions: Based on a modified Delphi expert consensus process, this report aims to inform on best practices for TTC delivery for patients following TBI, and to highlight areas of need for further research to improve clinical guidelines in this setting.

Published
2024

19. Systematic screening on admission for SARS-CoV-2 to detect asymptomatic infections

Author

Stadler, Rahel N., Maurer, Laura, Aguilar-Bultet, Lisandra, Franzeck, Fabian, Ruchti, Chantal, Kühl, Richard, Widmer, Andreas F., Schindler, Ruth, Bingisser, Roland, Rentsch, Katharina M., Pargger, Hans, Sutter, Raoul, Steiner, Luzius, Meier, Christoph, Kübler, Werner, Hirsch, Hans H., Egli, Adrian, Battegay, Manuel, Bassetti, Stefano, and Tschudin-Sutter, Sarah

Published
2021
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25. Guideline adherence to statin therapy and association with short-term and long-term cardiac complications following noncardiac surgery

Author

Glarner, Noemi, primary, Puelacher, Christian, additional, Gualandro, Danielle Menosi, additional, Lurati Buse, Giovanna, additional, Hidvegi, Reka, additional, Bolliger, Daniel, additional, Lampart, Andreas, additional, Burri, Katrin, additional, Pargger, Mirjam, additional, Gerhard, Hatice, additional, Weder, Samantha, additional, Maiorano, Silvia, additional, Meister, Rebecca, additional, Tschan, Carla, additional, Osswald, Stefan, additional, Steiner, Luzius A., additional, Guerke, Lorenz, additional, Kappos, Elisabeth A., additional, Clauss, Martin, additional, Filipovic, Miodrag, additional, Arenja, Nisha, additional, and Mueller, Christian, additional

Published
2023
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33. Acute heart failure after non-cardiac surgery: incidence, phenotypes, determinants and outcomes

Author

Gualandro, Danielle M. M., Puelacher, Christian, Chew, Michelle, Andersson, Henrik, Buse, Giovanna Lurati, Glarner, Noemi, Mueller, Daria, Cardozo, Francisco A. M., Burri-Winkler, Katrin, Mork, Constantin, Wussler, Desiree, Shrestha, Samyut, Heidelberger, Isabelle, Fält, Mikael, Hidvegi, Reka, Bolliger, Daniel, Lampart, Andreas, Steiner, Luzius A. A., Scharen, Stefan, Kindler, Christoph, Gurke, Lorenz, Rikli, Daniel, Lardinois, Didier, Osswald, Stefan, Buser, Andreas, Caramelli, Bruno, Mueller, Christian, Gualandro, Danielle M. M., Puelacher, Christian, Chew, Michelle, Andersson, Henrik, Buse, Giovanna Lurati, Glarner, Noemi, Mueller, Daria, Cardozo, Francisco A. M., Burri-Winkler, Katrin, Mork, Constantin, Wussler, Desiree, Shrestha, Samyut, Heidelberger, Isabelle, Fält, Mikael, Hidvegi, Reka, Bolliger, Daniel, Lampart, Andreas, Steiner, Luzius A. A., Scharen, Stefan, Kindler, Christoph, Gurke, Lorenz, Rikli, Daniel, Lardinois, Didier, Osswald, Stefan, Buser, Andreas, Caramelli, Bruno, and Mueller, Christian

Abstract

Aims Primary acute heart failure (AHF) is a common cause of hospitalization. AHF may also develop postoperatively (pAHF). The aim of this study was to assess the incidence, phenotypes, determinants and outcomes of pAHF following non-cardiac surgery.Methods and results A total of 9164 consecutive high-risk patients undergoing 11 262 non-cardiac inpatient surgeries were prospectively included. The incidence, phenotypes, determinants and outcome of pAHF, centrally adjudicated by independent cardiologists, were determined. The incidence of pAHF was 2.5% (95% confidence interval [CI] 2.2-2.8%); 51% of pAHF occurred in patients without known heart failure (de novo pAHF), and 49% in patients with chronic heart failure. Among patients with chronic heart failure, 10% developed pAHF, and among patients without a history of heart failure, 1.5% developed pAHF. Chronic heart failure, diabetes, urgent/emergent surgery, atrial fibrillation, cardiac troponin elevations above the 99th percentile, chronic obstructive pulmonary disease, anaemia, peripheral artery disease, coronary artery disease, and age, were independent predictors of pAHF in the logistic regression model. Patients with pAHF had significantly higher all-cause mortality (44% vs. 11%, p < 0.001) and AHF readmission (15% vs. 2%, p < 0.001) within 1 year than patients without pAHF. After Cox regression analysis, pAHF was an independent predictor of all-cause mortality (adjusted hazard ratio [aHR] 1.7 [95% CI 1.3-2.2]; p < 0.001) and AHF readmission (aHR 2.3 [95% CI 1.5-3.7]; p < 0.001). Findings were confirmed in an external validation cohort using a prospective multicentre cohort of 1250 patients (incidence of pAHF 2.4% [95% CI 1.6-3.3%]).Conclusions Postoperative AHF frequently developed following non-cardiac surgery, being de novo in half of cases, and associated with a very high mortality., Funding Agencies|Swiss National Science Foundation; Swiss Heart Foundation; University Hospital Basel; University of Basel; AstraZeneca; Abbott; Roche; Clinical Research Program of the University of Basel; Spezialprogramm Nachwuchsforderung Klinische Forschung; Forderung Exzellenter Junger Forschender; Forschung fond Kantonsspital Aarau; Swiss Academy of Medical Sciences; Bangerter Foundation; Fundacao de Amparo a Pesquisa do Estado de Sao Paulo; Brazil [FAPESP] [2015/23731-6]; Swedish Research Council [2019-02833]; South Eastern Sweden Research Council [746981, 712291]; LinkopingUniversity-Region_Osterg_otland ALF [687681, 792291]

Published
2023
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34. Impact of sedation and vasopressors on in vivo cerebrovascular reactivity in adult moderate/severe traumatic brain injury (TBI)

Author

Kazina, Colin (Neurosurgery), Ashraf, Ahmed (Electrical and Computer Engineering), Unger, Bertram (Otolaryngology), Steiner, Luzius (Anesthesiology and Acute Medicine, University Hospital Basel), Zeiler, Frederick A., Froese, Logan, Kazina, Colin (Neurosurgery), Ashraf, Ahmed (Electrical and Computer Engineering), Unger, Bertram (Otolaryngology), Steiner, Luzius (Anesthesiology and Acute Medicine, University Hospital Basel), Zeiler, Frederick A., and Froese, Logan

Abstract

Traumatic brain injury (TBI) is one of the leading causes of death and disability both in Canada and worldwide. Despite TBIs’ extensive impact on healthcare there has been limited overall improvement over the past four decades. However, the secondary injuries associated with TBI (those being the cascading physiological events that lead to increased tissue damage) are theoretically targetable by critical care. Of these secondary injuries, cerebral autoregulation (CA; the innate ability to maintain healthy homeostasis of cerebral blood flow) has gained extensive interest given it has been independently linked to mortality and poor outcomes. CA is often measured through the surrogate measure of cerebrovascular reactivity (CVR) and has been assessed in TBI related critical care. To date, current care appears to have a limited impact on CVR, with many patients having extensive periods of care dominated by impaired CVR. This has sparked interest in the mediation of CVR, though there is still a lot unknown surrounding the drivers of impaired CVR after TBI. Thus, this thesis aims to help answer the following questions: a) what is the relationship between current guideline-based agents (vasopressor and sedative agents) administered in vivo and CVR? and b) what is the relationship between objectively measured depth of sedation and CVR/cerebral physiologies? This work evaluated several cerebral physiologic indices and CVR measures with in vivo sedative and vasopressor agents. Current critical care guideline-driven use of vasopressor and sedative agents has a limited impact on CVR measures, when evaluated in a dose-based fashion with high-frequency cerebral physiology. Moreover, impaired CVR measures appear to be relatively treatment independent from current care. Additionally, this work explored the relationship between objective depth of sedation and CVR. Such work documented a unique relationship between these measures, where CVR can in theory be mediated by the depth of sed

Published
2023

35. Prediction of perioperative myocardial infarction/injury in high-risk patients after noncardiac surgery

Author

Meister, Rebecca, Puelacher, Christian, Glarner, Noemi, Gualandro, Danielle Menosi, Andersson, Henrik, Pargger, Mirjam, Hure, Gabrielle, Virant, Georgiana, Bolliger, Daniel, Lampart, Andreas, Steiner, Luzius, Hidvegi, Reka, Buse, Giovanna Lurati, Kindler, Christoph, Gurke, Lorenz, Mujagic, Edin, Schaeren, Stefan, Clauss, Martin, Lardinois, Didier, Hammerer-Lercher, Angelika, Chew, Michelle, Mueller, Christian, Meister, Rebecca, Puelacher, Christian, Glarner, Noemi, Gualandro, Danielle Menosi, Andersson, Henrik, Pargger, Mirjam, Hure, Gabrielle, Virant, Georgiana, Bolliger, Daniel, Lampart, Andreas, Steiner, Luzius, Hidvegi, Reka, Buse, Giovanna Lurati, Kindler, Christoph, Gurke, Lorenz, Mujagic, Edin, Schaeren, Stefan, Clauss, Martin, Lardinois, Didier, Hammerer-Lercher, Angelika, Chew, Michelle, and Mueller, Christian

Abstract

Aims Perioperative myocardial infarction/injury (PMI) is a surprisingly common yet difficult-to-predict cardiac complication in patients undergoing noncardiac surgery. We aimed to assess the incremental value of preoperative cardiac troponin (cTn) concentration in the prediction of PMI. Methods and results Among prospectively recruited patients at high cardiovascular risk (age >= 65 years or >= 45 years with preexisting cardiovascular disease), PMI was defined as an absolute increase in high-sensitivity cTnT (hs-cTnT) concentration of >= 14 ng/L (the 99th percentile) above the preoperative concentration. Perioperative myocardial infarction/injury was centrally adjudicated by two independent cardiologists using serial measurements of hs-cTnT. Using logistic regression, three models were derived: Model 1 including patient- and procedure-related information, Model 2 adding routinely available laboratory values, and Model 3 further adding preoperative hs-cTnT concentration. Models were also compared vs. preoperative hs-cTnT alone. The findings were validated in two independent cohorts. Among 6944 patients, PMI occurred in 1058 patients (15.2%). The predictive accuracy as quantified by the area under the receiver operating characteristic curve was 0.73 [95% confidence interval (CI) 0.71-0.74] for Model 1, 0.75 (95% CI 0.74-0.77) for Model 2, 0.79 (95% CI 0.77-0.80) for Model 3, and 0.74 for hs-cTnT alone. Model 3 included 10 preoperative variables: age, body mass index, known coronary artery disease, metabolic equivalent >4, risk of surgery, emergency surgery, planned duration of surgery, haemoglobin, platelet count, and hs-cTnT. These findings were confirmed in both independent validation cohorts (n = 722 and n = 966). Conclusion Preoperative cTn adds incremental value above patient- and procedure-related variables as well as routine laboratory variables in the prediction of PMI., Funding Agencies|Swiss National Science Foundation; University Basel; Universitatsspital Basel; Swiss Heart Foundation; Roche Diagnostics; Abbott; Astra Zeneca Schweiz; Cardiovascular Research Foundation Basel; Fundacao de Amparo a Pesquisa do Estado de Sao Paulo, Brazil (FAPESP) [2015/23731-6]

Published
2023
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36. Independent External Validation of a Preoperative Prediction Model for Delirium After Cardiac Surgery: A Prospective Observational Cohort Study

Author

Wueest, Alexandra S, Berres, Manfred, Bettex, Dominique A, Steiner, Luzius A, Monsch, Andreas U, Goettel, Nicolai; https://orcid.org/0000-0003-0191-9775, Wueest, Alexandra S, Berres, Manfred, Bettex, Dominique A, Steiner, Luzius A, Monsch, Andreas U, and Goettel, Nicolai; https://orcid.org/0000-0003-0191-9775

Abstract

Objective: This investigation provided independent external validation of an existing preoperative risk prediction model. Design: A prospective observational cohort study of patients undergoing cardiac surgery covering the period between April 16, 2018 and January 18, 2022. Setting: Two academic hospitals in Switzerland. Participants: Adult patients (≥60 years of age) who underwent elective cardiac surgery, including coronary artery bypass graft, mitral or aortic valve replacement or repair, and combined procedures. Interventions: None. Measurements and main results: The primary outcome measure was the incidence of postoperative delirium (POD) in the intensive or intermediate care unit, diagnosed using the Intensive Care Delirium Screening Checklist. The prediction model contained 4 preoperative risk factors to which the following points were assigned: Mini-Mental State Examination (MMSE) score ≤23 received 2 points; MMSE 24-27, Geriatric Depression Scale (GDS) >4, prior stroke and/or transient ischemic attack (TIA), and abnormal serum albumin (≤3.5 or ≥4.5 g/dL) received 1 point each. The missing data were handled using multiple imputation. In total, 348 patients were included in the study. Sixty patients (17.4%) developed POD. For point levels in the prediction model of 0, 1, 2, and ≥3, the cumulative incidence of POD was 12.6%, 22.8%, 25.8%, and 35%, respectively. The validation resulted in a pooled area under the receiver operating characteristics curve of 0.60 (median CI, 0.525-0.679). Conclusions: The evaluated predictive model for delirium after cardiac surgery in this patient cohort showed only poor discriminative capacity but fair calibration. Keywords: External validation; cardiac surgery; delirium; prediction

Published
2023

40. Contributors

Author

Benkreira, Aymen, primary, Bilotta, Federico, additional, Bonhomme, Vincent, additional, Borozdina, Anastasia, additional, Chaikittisilpa, Nophanan, additional, Cournoyer, Alexis, additional, Cueni, Nadine, additional, Defresne, Aline, additional, Denault, André Y., additional, Evered, Lis, additional, Franssen, Colette, additional, Hollinger, Alexa, additional, James, Michael L., additional, Koht, Antoun, additional, Lele, Abhijit V., additional, Mailhot, Tanya, additional, Matta, Basil, additional, McLawhorn, Marc, additional, Prabhakar, Hemanshu, additional, Ramani, Ramachandran, additional, Rasulo, Frank, additional, Robba, Chiara, additional, Shaaban-Ali, Mohamed, additional, Sharma, Deepak, additional, Siegemund, Martin, additional, Sloan, Tod B., additional, Steiner, Luzius A., additional, Tran, Gabriel, additional, Varanini, Niccoló, additional, and Vavilala, Monica S., additional

Published
2018
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43. Reporting Essentials for DElirium bioMarker Studies (REDEEMS): Explanation and Elaboration

Author

Amgarth-Duff, Ingrid, primary, Hosie, Annemarie, additional, Caplan, Gideon A., additional, Adamis, Dimitrios, additional, Watne, Leiv Otto, additional, Cunningham, Colm, additional, Oh, Esther S, additional, Wang, Sophia, additional, Lindroth, Heidi, additional, Sanders, Robert D, additional, Olofsson, Birgitta, additional, Girard, Timothy D, additional, Steiner, Luzius A, additional, Vasunilashorn, Sarinnapha M, additional, and Agar, Meera, additional

Published
2022
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47. Perioperative Myocardial Injury After Noncardiac Surgery: Incidence, Mortality, and Characterization

Author

Puelacher, Christian, Lurati Buse, Giovanna, Seeberger, Daniela, Sazgary, Lorraine, Marbot, Stella, Lampart, Andreas, Espinola, Jaqueline, Kindler, Christoph, Hammerer, Angelika, Seeberger, Esther, Strebel, Ivo, Wildi, Karin, Twerenbold, Raphael, du Fay de Lavallaz, Jeanne, Steiner, Luzius, Gurke, Lorenz, Breidthardt, Tobias, Rentsch, Katharina, Buser, Andreas, Gualandro, Danielle M., Osswald, Stefan, Mueller, Christian, Seeberger, Manfred, Christ-Crain, Mirjam, Cuculi, Florim, Badertscher, Patrick, Nestelberger, Thomas, Wussler, Desiree, Flores, Dayana, Boeddinghaus, Jasper, Sabti, Zaid, Giménez, Maria Rubini, Kozhuharov, Nikola, Shrestha, Samyut, Kloos, Wanda, Lohrmann, Jens, Reichlin, Tobias, Freese, Michael, Meissner, Kathrin, Kaiser, Christoph, and Buser, Andreas

Published
2018
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50. Intraoperative positive end-expiratory pressure and postoperative pulmonary complications: a patient-level meta-analysis of three randomised clinical trials

Author

Campos, Niklas S., primary, Bluth, Thomas, additional, Hemmes, Sabrine N.T., additional, Librero, Julian, additional, Pozo, Natividad, additional, Ferrando, Carlos, additional, Ball, Lorenzo, additional, Mazzinari, Guido, additional, Pelosi, Paolo, additional, Gama de Abreu, Marcelo, additional, Schultz, Marcus J., additional, Serpa Neto, A., additional, Hemmes, Sabrine NT., additional, Severgnini, Paolo, additional, Hollmann, Markus W., additional, Binnekade, Jan M., additional, Wrigge, Hermann, additional, Canet, Jaume, additional, Hiesmayr, Michael, additional, Schmid, Werner, additional, Tschernko, Edda, additional, Jaber, Samir, additional, Hedenstierna, Göran, additional, Putensen, Christian, additional, Marti, Agnes, additional, Bacuzzi, Alessandro, additional, Brodhun, Alexander, additional, Molin, Alexandre, additional, Merten, Alfred, additional, Parera, Ana, additional, Brunelli, Andrea, additional, Cortegiani, Andrea, additional, Güldner, Andreas, additional, Reske, Andreas W., additional, Gratarola, Angelo, additional, Giarratano, Antonino, additional, Bastin, Bea, additional, Heyse, Bjorn, additional, Mazul-Sunko, Branka, additional, Amantea, Bruno, additional, Barberis, Bruno, additional, Uhlig, Christopher, additional, Marín, Conrado Minguez, additional, Celentano, Cristian, additional, La Bella, Daniela, additional, D’Antini, David, additional, Velghe, David, additional, Sulemanji, Demet, additional, De Robertis, Edoardo, additional, Hartmann, Eric, additional, Montalto, Francesca, additional, Tropea, Francesco, additional, Mills, Gary H., additional, Cinnella, Gilda, additional, Della Rocca, Giorgio, additional, Caggianelli, Girolamo, additional, Pellerano, Giulia, additional, Mollica, Giuseppina, additional, Bugedo, Guillermo, additional, Mulier, Jan-Paul, additional, Vandenbrande, Jeroen, additional, Geib, Johann, additional, Yaqub, Jonathan, additional, Florez, Jorge, additional, Mayoral, Juan F., additional, Sprung, Juraj, additional, Van Limmen, Jurgen, additional, Bos, Lieuwe DJ., additional, de Baerdemaeker, Luc, additional, Jamaer, Luc, additional, Spagnolo, Luigi, additional, Strys, Lydia, additional, Gil, Manuel Granell, additional, Vidal Melo, Marcos F., additional, Unzueta, Maria Carmen, additional, Moral, Maria Victoria, additional, Ferner, Marion, additional, Weiss, Martin, additional, Vanoni, Massimo, additional, Schaefer, Maximilian S., additional, Prieto, Mercè, additional, Grio, Michele, additional, Spieth, Peter Markus, additional, Simon, Philipp, additional, Bodger, Phoebe, additional, Sierra, Pilar, additional, Laufenberg-Feldmann, Rita, additional, Rusca, Roberta, additional, Proietti, Rodolfo, additional, Raineri, Santi Maurizio, additional, Caroleo, Santo, additional, Sabaté, Sergi, additional, De Hert, Stefan, additional, Pezzato, Stefano, additional, Treschan, Tanja A., additional, Goranovic, Tatjana, additional, Koch, Thea, additional, Kiss, Thomas, additional, Perilli, Valter, additional, Cegarra, Virginia, additional, Belda, Javier, additional, Soro, Marina, additional, Unzueta, Carmen, additional, Suarez-Sipmann, Fernando, additional, Librero, Julián, additional, Llombart, Alicia, additional, Rovira, Lucas, additional, Granell, Manuel, additional, Aldecoa, César, additional, Diaz-Cambronero, Oscar, additional, Balust, Jaume, additional, Garutti, Ignacio, additional, Gonzalez, Rafael, additional, Gallego, Lucia, additional, Garcia del Valle, Santiago, additional, Redondo, Javier, additional, Pestaña, David, additional, Rodríguez, Aurelio, additional, García, Javier, additional, Matta, Manuel de la, additional, Ibáñez, Maite, additional, Barrios, Francisco, additional, Hernández, Samuel, additional, Torres, Vicente, additional, Peiró, Salvador, additional, Villena, Abigail, additional, Carramiñana, Albert, additional, Gallego-Casilda, Alberto, additional, Duca, Alejandro, additional, Alcón, Amalia, additional, Miñana, Amanda, additional, Asensio, Ana, additional, Colás, Ana, additional, Galve, Ana Isabel, additional, Izquierdo, Ana, additional, Jurado, Ana, additional, Pérez, Ana María, additional, Mugarra, Ana, additional, Gutierrez, Andrea, additional, De Miguel, Ángeles, additional, Lozano, Angels, additional, Katime, Antonio, additional, Romero, Antonio, additional, Garrigues, Beatriz, additional, Ayas, Begoña, additional, Arocas, Blanca, additional, Delgado, Carlos, additional, Fernández, Carmen, additional, Romero, Carolina, additional, Gallego, Clara, additional, Garcés, Cristina, additional, Lisbona, Cristina, additional, Parrilla, Cristina, additional, López-Herrera, Daniel, additional, González, Domingo, additional, Llamazares, Eduardo, additional, Del Rio, Elena, additional, Lozano, Elena, additional, Pastor, Ernesto, additional, Chamorro, Estefanía, additional, Gracia, Estefanía, additional, Sánchez, Ester, additional, Romero, Esther, additional, Díez, Fernando, additional, Serralta, Ferran, additional, Daviu, Francisco, additional, Sandín, Francisco, additional, Aguilar, Gerardo, additional, Tusman, Gerardo, additional, Azparren, Gonzalo, additional, Martínez-Pallí, Graciela, additional, Benítez, Inmaculada, additional, Hernandéz, Inmaculada, additional, India, Inmaculada, additional, León, Irene, additional, Fuentes, Isabel, additional, Ruiz, Isabel, additional, Puig, Jaume, additional, Román, Javie Ignacio, additional, Acosta, Jesús, additional, Rico-Feijoo, Jesús, additional, Olmedo, Jonathan, additional, Carbonell, Jose A., additional, Alonso, Jose M., additional, Pérez, Jose María, additional, Marcos, Jose Miguel, additional, Navarro, Jose, additional, Valdivia, Jose, additional, Carrizo, Juan, additional, Piqueras, Laura, additional, Soriano, Laura, additional, Vaquero, Laura, additional, Miguel, Lisset, additional, Muñoz, Lorena, additional, Valencia, Lucia, additional, Olmedilla, Luis, additional, Etulain, Mᵃ Justina, additional, Tisner, Manuel, additional, Barrio, María, additional, Alonso, María Dolores, additional, García, María, additional, Hernández, María J., additional, Alberola, María José, additional, Parra, María, additional, Argente, María Pilar, additional, Vila, María, additional, De Fez, Mario, additional, Agilaga, Marta, additional, Gine, Marta, additional, Ayuso, Mercedes, additional, García, Mercedes, additional, Bejarano, Natalia, additional, Peña, Natalia, additional, Ojeda, Nazario, additional, Martínez, Nilda, additional, García, Nuria, additional, Padrón, Oto, additional, García, Pablo, additional, Valls, Paola, additional, Cruz, Patricia, additional, Piñeiro, Patricia, additional, Charco, Pedro, additional, Anaya, Rafael, additional, López, Ramiro, additional, Rodríguez, Rayco, additional, Martínez, Rocío, additional, Pujol, Roger, additional, Dosdá, Rosa, additional, Lardies, Rosa, additional, Díaz, Ruben, additional, Villazala, Rubén, additional, Zapatero, Sara, additional, Cabrera, Sergio, additional, Sánchez, Sergio, additional, Martin, Silvia, additional, Diaz, Suzana, additional, Franco, Tania, additional, Moreno, Tania, additional, Socorro, Tania, additional, Gilabert, Vicente, additional, Balandrón, Victor, additional, Moral, Victoria, additional, Cegarra, Virgina, additional, Varón, Viviana, additional, Abelha, Fernando, additional, Abitağaoğlu, Sühayla, additional, Achilles, Marc, additional, Adebesin, Afeez, additional, Adriaensens, Ine, additional, Ahene, Charles, additional, Akbar, Fatima, additional, Al Harbi, Mohammed, additional, Al Khoury al Kallab, Rita, additional, Albanel, Xavier, additional, Aldenkortt, Florence, additional, Saleh Alfouzan, Rawan Abdullah, additional, Alruqaie, Reef, additional, Altermatt, Fernando, additional, Luís de Castro Araujo, Bruno, additional, Arbesú, Genaro, additional, Artsi, Hanna, additional, Aurilio, Caterina, additional, Ayanoglu, Omer Hilmi, additional, Baig, Harris, additional, Baird, Yolanda, additional, Balonov, Konstantin, additional, Banks, Samantha, additional, Bao, Xiaodong, additional, Baumgartner, Mélanie, additional, Tortosa, Isabel Belda, additional, Bergamaschi, Alice, additional, Bergmann, Lars, additional, Bigatello, Luca, additional, Pérez, Elena Biosca, additional, Birr, Katja, additional, Bojaxhi, Elird, additional, Bonenti, Chiara, additional, Bonney, Iwona, additional, Bos, Elke M.E., additional, Bowman, Sara, additional, Braz, Leandro Gobbo, additional, Brugnoni, Elisa, additional, Brull, Sorin J., additional, Brunetti, Iole, additional, Bruni, Andrea, additional, Buenvenida, Shonie L., additional, Busch, Cornelius Johannes, additional, Camerini, Giovanni, additional, Capatti, Beatrice, additional, Carmona, Javiera, additional, Carungcong, Jaime, additional, Carvalho, Marta, additional, Cattan, Anat, additional, Cavaleiro, Carla, additional, Chiumello, Davide, additional, Ciardo, Stefano, additional, Coburn, Mark, additional, Colella, Umberto, additional, Contreras, Victor, additional, Dincer, Pelin Corman, additional, Cotter, Elizabeth, additional, Crovetto, Marcia, additional, Darrah, William, additional, Davies, Simon, additional, Del Cojo Peces, Enrique, additional, Delphin, Ellise, additional, Diaper, John, additional, Junior, Paulo do Nascimento, additional, Donatiello, Valerio, additional, Dong, Jing, additional, Dourado, Maria do Socorro, additional, Dullenkopf, Alexander, additional, Ebner, Felix, additional, Elgendy, Hamed, additional, Ellenberger, Christoph, additional, Arı, Dilek Erdoğan, additional, Ermert, Thomas, additional, Farah, Fadi, additional, Fernandez-Bustamante, Ana, additional, Ferreira, Cristina, additional, Fiore, Marco, additional, Fonte, Ana, additional, Palahí, Christina Fortià, additional, Galimberti, Andrea, additional, Garofano, Najia, additional, Giaccari, Luca Gregorio, additional, Gilsanz, Fernando, additional, Girrbach, Felix, additional, Gobbi, Luca, additional, Godfried, Marc Bernard, additional, Goettel, Nicolai, additional, Goldstein, Peter A., additional, Goren, Or, additional, Gorlin, Andrew, additional, Graterol, Juan, additional, Guyon, Pierre, additional, Haire, Kevin, additional, Harou, Philippe, additional, Helf, Antonia, additional, Hempel, Gunther, additional, Hernández Cádiz, María José, additional, Heyse, Björn, additional, Huercio, Ivan, additional, Ilievska, Jasmina, additional, Jakus, Lien, additional, Jeganath, Vijay, additional, Jelting, Yvonne, additional, Jung, Minoa, additional, Kabon, Barbara, additional, Kacha, Aalok, additional, Ilić, Maja Karaman, additional, Karuppiah, Arunthevaraja, additional, Kavas, Ayse Duygu, additional, Barcelos, Gleicy Keli, additional, Kellogg, Todd A., additional, Kemper, Johann, additional, Kerbrat, Romain, additional, Khodr, Suraya, additional, Kienbaum, Peter, additional, Kir, Bunyamin, additional, Kivrak, Selin, additional, Klarić, Vlasta, additional, Köksal, Ceren, additional, Kowark, Ana, additional, Kranke, Peter, additional, Kuvaki, Bahar, additional, Kuzmanovska, Biljana, additional, Laffey, John, additional, Lange, Mirko, additional, Freitas de Lemos, Marília, additional, Licker, Marc-Joseph, additional, López-Baamonde, Manuel, additional, López-Hernández, Antonio, additional, Lopez-Martinez, Mercedes, additional, Luise, Stéphane, additional, MacGregor, Mark, additional, Magalhães, Danielle, additional, Maillard, Julien, additional, Malerbi, Patrizia, additional, Manimekalai, Natesan, additional, Margarson, Michael, additional, Markstaller, Klaus, additional, Martin, Archer K., additional, Martin, David P., additional, Martin, Yvette N., additional, Martínez-Ocon, Julia, additional, Martin-Loeches, Ignacio, additional, Maseda, Emilio, additional, Matot, Idit, additional, McAuliffe, Niamh, additional, McKenzie, Travis J., additional, Medina, Paulina, additional, Meersch, Melanie, additional, Menzen, Angelika, additional, Mertens, Els, additional, Meurer, Bernd, additional, Meyer-Treschan, Tanja, additional, Miao, Changhong, additional, Micalizzi, Camilla, additional, Milić, Morena, additional, Pinheiro Módolo, Norma Sueli, additional, Moine, Pierre, additional, Mölders, Patrick, additional, Montero-Feijoo, Ana, additional, Moret, Enrique, additional, Muller, Markus K., additional, Murphy, Zoe, additional, Nalwaya, Pramod, additional, Naumovski, Filip, additional, Navalesi, Paolo, additional, Navarro e Lima, Lais Helena, additional, Adam, Višnja Nesek, additional, Neumann, Claudia, additional, Newell, Christopher, additional, Nisnevitch, Zoulfira, additional, Nizamuddin, Junaid, additional, Novazzi, Cecilia, additional, O'Connor, Michael, additional, Oprea, Günther, additional, Sungur, Mukadder Orhan, additional, Özbilgin, Şule, additional, Pace, Maria Caterina, additional, Pacheco, Marcos, additional, Packianathaswamy, Balaji, additional, Gonzalez, Estefania Palma, additional, Papaspyros, Fotios, additional, Paredes, Sebastián, additional, Passavanti, Maria Beatrice, additional, Pedemonte, Juan Cristobal, additional, Peremin, Sanja, additional, Philipsenburg, Christoph, additional, Pinho, Daniela, additional, Pinho, Silvia, additional, Posthuma, Linda M., additional, Pota, Vincenzo, additional, Preckel, Benedikt, additional, Priani, Paolo, additional, Rached, Mohamed Aymen, additional, Radoeshki, Aleksandar, additional, Ragazzi, Riccardo, additional, Rajamanickam, Tamilselvan, additional, Rajamohan, Arthi, additional, Ramakrishna, Harish, additional, Rangarajan, Desikan, additional, Reiterer, Christian, additional, Renew, J. 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2022
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