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44 results on '"Steinberg, Ran"'

34. Colorectal Carcinoma in Childhood: A Retrospective Multicenter Study

Author

Kravarusic, Dragan, primary, Feigin, Elad, additional, Dlugy, Elena, additional, Steinberg, Ran, additional, Baazov, Arthur, additional, Erez, Ilan, additional, Lazar, Ludvig, additional, Kapuller, Vadim, additional, Grunspan, Moshe, additional, Ash, Shifra, additional, and Freud, Enrique, additional

Published
2007
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39. Kingella KingaeChest Mass Mimicking a Tumor in an 11-Month-Old Baby

Author

Dabaja-Younis, Halima, Kassis, Imad, Ilivitzki, Anat, Steinberg, Ran, and Shachor-Meyouhas, Yael

Abstract

Supplemental Digital Content is available in the text.Kingella kingaehas been recognized as a common etiology of pediatric osteoarticular infections, especially among children younger than 5 years of age. In recent years, there have been reported cases of unusual manifestations. We report a rare case of a chest mass mimicking a tumor in an 11-month-old baby.

Published
2017
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42. 2p24 Gain Region Harboring MYCNGene Compared with MYCNAmplified and Nonamplified Neuroblastoma

Author

Jeison, Marta, Ash, Shifra, Halevy-Berko, Gili, Mardoukh, Jacques, Luria, Drorit, Avigad, Smadar, Feinberg-Gorenshtein, Galina, Goshen, Yacov, Hertzel, Gabriel, Kapelushnik, Joseph, Barak, Ayelet Ben, Attias, Dina, Steinberg, Ran, Stein, Jerry, Stark, Batia, and Yaniv, Isaac

Abstract

Although the role of MYCNamplification in neuroblastoma is well established, the biological and clinical characteristics of the 2p gain region harboring the MYCNgene remain unclear. The aim of this study was to compare the biological and clinical characteristics of these tumors with MYCNamplified and nonamplified neuroblastoma and to determine their impact on disease outcome. Samples from 177 patients were analyzed by fluorescence in situhybridization, including MYCN, 1p, 17q, and 11q regions; 2p gain was identified in 25 patients, MYCNamplification in 31, and no amplification in 121 patients. Patients with 2p gain had a significantly worse 5-year event-free survival rate than patients with no MYCNamplified (P< 0.001), and an intermediate 5-year overall survival rate difference existed between the MYCNamplified tumors (P= 0.025) and nonamplified (P= 0.003) groups. All of the 2p gain samples were associated with segmental and/or numerical alterations in the other tested regions. The presence of segmental alterations with or without MYCNamplification was recently found to be the strongest predictor of relapse in a multivariate analysis. The results of the present study suggest that the determination of MYCNgene copy number relative to chromosome 2, when evaluating MYCNstatus at diagnosis, may help to reveal the underlying genetic pattern of these tumors and better understand their clinical behavior.

Published
2010
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44. Two year experience with minimal access surgery at Schneider Children's Medical Center of Israel.

Author

Kravarusic D, Dlugy E, Steinberg R, Paloi B, Baazov A, Feigin E, and Freud E

Subjects
Adolescent, Child, Child, Preschool, Female, Hospitals, Pediatric, Humans, Infant, Israel, Male, Medical Records, Laparoscopy statistics & numerical data, Minimally Invasive Surgical Procedures statistics & numerical data, Thoracoscopy statistics & numerical data
Abstract

Background: The minimal access surgery revolution has only just begun to impact on pediatric surgery, thanks mainly to technologic advances and evidence of the benefits of minimally invasive procedures in this population., Objectives: To review the current status of MAS in a pediatric tertiary care center in Israel, in terms of feasibility, safety, and effect on standard practices., Methods: We reviewed the files of all children who underwent a MAS procedure in our department during the period April 2002 to July 2004, and compared the findings with those of children treated by standard practices., Results: A total of 301 procedures were performed in 271 patients: 107 thoracoscopic and 194 laparoscopic. There were no major intraoperative complications. The total conversion rate was 3.65%: 0 for thoracoscopy and 5.6% for laparoscopy (11/194). Twenty-four types of procedures were performed during the study period. The thoracoscopies accounted for 92.24% of all thoracic procedures in the department (107/116), and routine abdominal laparoscopic procedures replaced open surgery in 30-100% of cases (total 44.8%, 194/433)., Conclusions: MAS procedures appear to be safe for a wide range of indications in children. In our center they currently account for a significant percentage of pediatric surgeries. We suggest that the integration of MAS training in the residency programs of pediatric surgeons be made a major long-term goal. The creation of a pediatric MAS study group that would allow for multi-institutional studies is especially important in Israel where a relatively large number of pediatric surgery departments handle a small annual number of patients.

Published
2005

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