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129 results on '"Steier, Jörg"'

11. Current and novel treatment options for obstructive sleep apnoea

Author

Randerath, Winfried, de Lange, Jan, Hedner, Jan, Ho, Jean Pierre T. F., Marklund, Marie E., Schiza, Sofia, Steier, Jörg, Verbraecken, Johan, Randerath, Winfried, de Lange, Jan, Hedner, Jan, Ho, Jean Pierre T. F., Marklund, Marie E., Schiza, Sofia, Steier, Jörg, and Verbraecken, Johan

Abstract

Obstructive sleep apnoea is a challenging medical problem due to its prevalence, its impact on quality of life and performance in school and professionally, the implications for risk of accidents, and comorbidities and mortality. Current research has carved out a broad spectrum of clinical phenotypes and defined major pathophysiological components. These findings point to the concept of personalised therapy, oriented on both the distinct clinical presentation and the most relevant pathophysiology in the individual patient. This leads to questions of whether sufficient therapeutic options other than positive airway pressure (PAP) alone are available, for which patients they may be useful, if there are specific indications for single or combined treatment, and whether there is solid scientific evidence for recommendations. This review describes our knowledge on PAP and non-PAP therapies to address upper airway collapsibility, muscle responsiveness, arousability and respiratory drive. The spectrum is broad and heterogeneous, including technical and pharmaceutical options already in clinical use or at an advanced experimental stage. Although there is an obvious need for more research on single or combined therapies, the available data demonstrate the variety of effective options, which should replace the unidirectional focus on PAP therapy.

Published
2022
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13. European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea

Author

Randerath, Winfried, primary, Verbraecken, Johan, additional, de Raaff, Christel A.L., additional, Hedner, Jan, additional, Herkenrath, Simon, additional, Hohenhorst, Winfried, additional, Jakob, Tina, additional, Marrone, Oreste, additional, Marklund, Marie, additional, McNicholas, Walter T., additional, Morgan, Rebecca L., additional, Pepin, Jean-Louis, additional, Schiza, Sofia, additional, Skoetz, Nicole, additional, Smyth, Dan, additional, Steier, Jörg, additional, Tonia, Thomy, additional, Trzepizur, Wojciech, additional, van Mechelen, Piet-Heijn, additional, and Wijkstra, Peter, additional

Published
2021
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19. Sauerstoff (O2)

Author

van Gestel, Arnoldus J.R., primary, Teschler, Helmut, additional, and Steier, Jörg, additional

Published
2014
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24. Pulmonalkreislauf

Author

van Gestel, Arnoldus J.R., primary, Schrimpf, M., additional, Teschler, Helmut, additional, and Steier, Jörg, additional

Published
2014
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25. Lagerung

Author

van Gestel, Arnoldus J.R., primary, Steier, Jörg, additional, and Teschler, Helmut, additional

Published
2014
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30. Diffusion

Author

van Gestel, Arnoldus J.R., primary, Teschler, Helmut, additional, and Steier, Jörg, additional

Published
2014
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34. European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea

Author

Randerath, Winfried, Verbraecken, Johan, de Raaff, Christel A. L., Hedner, Jan, Herkenrath, Simon, Hohenhorst, Winfried, Jakob, Tina, Marrone, Oreste, Marklund, Marie E., McNicholas, Walter T., Morgan, Rebecca L., Pepin, Jean-Louis, Schiza, Sofia, Skoetz, Nicole, Smyth, Dan, Steier, Jörg, Tonia, Thomy, Trzepizur, Wojciech, van Mechelen, Piet-Heijn, Wijkstra, Peter, Randerath, Winfried, Verbraecken, Johan, de Raaff, Christel A. L., Hedner, Jan, Herkenrath, Simon, Hohenhorst, Winfried, Jakob, Tina, Marrone, Oreste, Marklund, Marie E., McNicholas, Walter T., Morgan, Rebecca L., Pepin, Jean-Louis, Schiza, Sofia, Skoetz, Nicole, Smyth, Dan, Steier, Jörg, Tonia, Thomy, Trzepizur, Wojciech, van Mechelen, Piet-Heijn, and Wijkstra, Peter

Abstract

Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. In this European Respiratory Society (ERS) guideline on non-continuous positive airway pressure (CPAP) therapies for OSA, we present recommendations determined by a systematic review of the literature. It is an update of the 2011 ERS statement on non-CPAP therapies, advanced into a clinical guideline. A multidisciplinary group of experts, including pulmonary, surgical, dentistry and ear-nose-throat specialists, methodologists and patient representatives considered the most relevant clinical questions (for both clinicians and patients) relating to the management of OSA. Eight key clinical questions were generated and a systematic review was conducted to identify published randomised clinical trials that answered these questions. We used the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach to assess the quality of the evidence and the strength of recommendations. The resulting guideline addresses gastric bypass surgery, custom-made dual-block mandibular advancement devices, hypoglossal nerve stimulation, myofunctional therapy, maxillo-mandibular osteotomy, carbonic anhydrase inhibitors and positional therapy. These recommendations can be used to benchmark quality of care for people with OSA across Europe and to improve outcomes.

Published
2021
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39. Lagerung

Author

van Gestel, A. J. R., primary, Steier, Jörg, additional, and Teschler, Helmut, additional

Published
2010
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42. Diffusion

Author

van Gestel, A. J. R., primary, Steier, Jörg, additional, and Teschler, Helmut, additional

Published
2010
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44. Sauerstoff (O2)

Author

van Gestel, A. J. R., primary, Steier, Jörg, additional, and Teschler, Helmut, additional

Published
2010
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