392 results on '"Stefanati, A."'
Search Results
2. Effect of variability of mechanical properties on the predictive capabilities of vulnerable coronary plaques.
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Marco Stefanati, Anna Corti, Valentina D. A. Corino, Martin R. Bennett, Zhongzhao Teng, Gabriele Dubini, and José Felix Rodriguez Matas
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- 2024
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3. Travellers’ risk behaviors and health problems: Post-travel follow up in two travel medicine centers in Italy
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Stefanati, A., Pierobon, A., Baccello, V., DeStefani, E., Gamberoni, D., Furlan, P., Sandri, F., Stano, A., Coin, P., Baldo, V., and Gabutti, G.
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- 2021
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4. An Unfitted Method with Elastic Bed Boundary Conditions for the Analysis of Heterogeneous Arterial Sections
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Stephan Gahima, Pedro Díez, Marco Stefanati, José Félix Rodríguez Matas, and Alberto García-González
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elastic bed boundary condition ,robin boundary condition ,immersed boundary method ,level set ,arterial biomechanics ,unfitted method ,Mathematics ,QA1-939 - Abstract
This manuscript presents a novel formulation for a linear elastic model of a heterogeneous arterial section undergoing uniform pressure in a quasi-static regime. The novelties are twofold. First, an elastic bed support on the external boundary (elastic bed boundary condition) replaces the classical Dirichlet boundary condition (i.e., blocking displacements at arbitrarily selected nodes) for elastic solids to ensure a solvable problem. In addition, this modeling approach can be used to effectively account for the effect of the surrounding material on the vessel. Secondly, to study many geometrical configurations corresponding to different patients, we devise an unfitted strategy based on the Immersed Boundary (IB) framework. It allows using the same (background) mesh for all possible configurations both to describe the geometrical features of the cross-section (using level sets) and to compute the solution of the mechanical problem. Results on coronary arterial sections from realistic segmented images demonstrate that the proposed unfitted IB-based approach provides results equivalent to the standard finite elements (FE) for the same number of active degrees of freedom with an average difference in the displacement field of less than 0.5%. However, the proposed methodology does not require the use of a different mesh for every configuration. Thus, it is paving the way for dimensionality reduction.
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- 2023
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5. Effect of myofibril architecture on the active contraction of dystrophic muscle. A mathematical model
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Stefanati, Marco, Torrente, Yvan, and Rodriguez Matas, José Félix
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- 2021
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6. Manicomiche: Madness, Language and the Dismantling of the Asylum in Gianni Celati’s Comiche
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Ronchi Stefanati, Michele, Diazzi, Alessandra, editor, and Sforza Tarabochia, Alvise, editor
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- 2019
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7. Influenza coverage rates in subjects with chronic heart diseases: results obtained in four consecutive immunisation seasons in the Local Health Unit of Ferrara (North Italy)'
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Armando Stefanati, Silvia Lupi, Gianluca Campo, Silvia Cocchio, Patrizia Furlan, Vincenzo Baldo, and Giovanni Gabutti
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Immunisation ,Influenza ,Coverage rate ,Immunisation season ,Chronic heart disease ,Exemption ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Seasonal influenza epidemics yearly affects 5–15% of the world’s population, resulting in 3–5 million serious cases and up to 650,000 deaths. According to the 2017–2019 Italian National Immunisation Plan, free immunisation is offered to the categories at increased risk of experience the complications of the infection (over 65 years old subjects, pregnant women and individuals with underlying conditions, including chronic heart diseases). Rising evidence suggests that influenza can trigger adverse cardiovascular events therefore the vaccination is recommended for secondary prevention of cardiovascular diseases. Despite this, the influenza coverage rate in subjects with chronic heart disease is underestimated. Methods The study investigated the coverage rate in four consecutive influenza seasons (from 2011/2012 to 2014/2015) in subjects that benefit from exemption from paying healthcare costs for chronic heart disease living in Local Health Unit (LHU) of Ferrara (Italy), comparing the databases of exemptions and immunisations. Results The levels of influenza vaccine uptake were unstable, reaching the 50.3% in 2011/2012 immunisation season and falling to 42.2% in the following year. Coverage rates increased with increasing age, without achieving the 75% target, neither in over 65 years old subjects. The logistic regression analysis showed that influenza coverage rates were statistically significant different (p
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- 2020
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8. Impact of Pertussis on the Italian population: Analysis of hospital discharge records in the period 2001–2014
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Brosio, Federica, Kuhdari, Parvanè, Cocchio, Silvia, Stefanati, Armando, Baldo, Vincenzo, and Gabutti, Giovanni
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- 2020
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9. A mathematical model of healthy and dystrophic skeletal muscle biomechanics
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Stefanati, Marco, Villa, Chiara, Torrente, Yvan, and Rodriguez Matas, José Félix
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- 2020
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10. Cineamatori militanti
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Michele Ronchi Stefanati
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engagement politique ,documentaires ,Ghirri ,éthique ,consumérisme ,Language and Literature - Abstract
Cet essai explore la relation entre l’œuvre cinématographique de Celati et la société contemporaine. Il s’agit de souligner que ses documentaires, comme ses textes, naissent d’une opposition évidente contre certains phénomènes qui caractérisent les sociétés contemporaines : les effets du consumérisme sur les rapports humains et sur l’environnement ; l’américanisation des habitudes ; le « maquillage » des effets du temps et de l’idée de la mort grâce à la chirurgie esthétique ; l’attitude néocolonialiste du tourisme en Afrique.
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- 2020
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11. Viral Respiratory Infections in Hematological Patients
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Giovanni Gabutti, Francesco De Motoli, Federica Sandri, Maria Vittoria Toffoletto, and Armando Stefanati
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Cancer ,Hematological malignancy ,Immunocompromised ,Respiratory viral infections ,Stem cell transplantation ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Viral infections of the respiratory system represent one of the most important complications in hematological patients in terms of both the severity of the clinical picture and its related impact on the duration of hospitalization, and of mortality. The most implicated viruses are those that commonly cause community-based respiratory diseases: respiratory syncytial virus, Influenza virus and rhinovirus. However, in some cases the clinical picture may be triggered by first infection with or reactivation of pathogens normally not responsible for clinically relevant diseases in immunocompetent subjects. This issue is currently being taken into greater consideration within the scientific community. However, the strong heterogeneity in the epidemiology and clinical expression of these infections and the lack of adequate therapeutic options imply that there is currently no uniform consensus on the best management of these patients. The main purpose of this review is to highlight which viruses are currently most implicated in the onset of these infections, what is their incidence in so heterogeneous and fragile patients and the factors that lead to disease's onset and evolution. Possible or available clinical management options, diagnostic and therapeutic tools, and preventive and prophylaxis measures are also discussed.
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- 2020
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12. Diagnostic anticipation to reduce emergency department length of stay: a retrospective cohort study in Ferrara University hospital, Italy
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Andrea Strada, Niccolò Bolognesi, Lamberto Manzoli, Giorgia Valpiani, Chiara Morotti, Francesca Bravi, Roberto Bentivegna, Elena Forini, Antonella Pesci, Armando Stefanati, Eugenio Di Ruscio, and Tiziano Carradori
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Emergency department ,Overcrowding ,Healthcare services research, retrospective cohort study ,Quality improvement ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Emergency Department (ED) crowding reduces staff satisfaction and healthcare quality and safety, which in turn increase costs. Despite a number of proposed solutions, ED length of stay (LOS) - a main cause of overcrowding - remains a major issue worldwide. This retrospective cohort study was aimed at evaluating the effectiveness on ED LOS of a procedure called “Diagnostic Anticipation” (DA), which consisted in anticipating the ordering of blood tests by nurses, at triage, following a diagnostic algorithm approved by physicians. Methods In the second half of 2019, the ED of the University Hospital of Ferrara, Italy, adopted the DA protocol on alternate weeks for all patients with chest pain, abdominal pain, and non-traumatic bleeding. A retrospective cohort study on DA impact was conducted. Using ED electronic data, LOS independent predictors (age, sex, NEDOCS and Priority Color Code, imaging tests, specialistic consultations, hospital admission) were evaluated through multiple regression. Results During the weeks when DA was adopted, as compared to control weeks, the mean LOS was shorter by 18.2 min for chest pain, but longer by 15.7 min for abdominal pain, and 33.3 for non-traumatic bleeding. At multivariate analysis, adjusting for age, gender, triage priority, specialist consultations, imaging test, hospitalization and ED crowding, the difference in visit time was significant for chest pain only (p
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- 2020
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13. Coronavirus: Update Related to the Current Outbreak of COVID-19
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Giovanni Gabutti, Erica d’Anchera, Federica Sandri, Marta Savio, and Armando Stefanati
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Coronavirus ,COVID-19 ,Infectious disease ,MERS ,Pneumonia ,Public health ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract In December 2019, some cases of viral pneumonia were epidemiologically related to a new coronavirus in the province of Hubei, China. Subsequently, there has been an increase in infections attributable to this virus throughout China and worldwide. The World Health Organization (WHO) has officially named the infection coronavirus disease 2019 (COVID-19), and the virus has been classified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This appears to be a virus from Rhinolophus bats, but the intermediate host has not yet been identified. The mechanism of infection of SARS-CoV-2 is not yet known; it appears to have affinity for cells located in the lower airways, where it replicates. The interhuman transmission of coronaviruses mainly occurs through saliva droplets and direct and indirect contact via surfaces. As of March 10, 2020, the number of cases worldwide was 113,702. Along with severe acute respiratory syndrome (SARS) and Middle Eastern respiratory syndrome (MERS), COVID-19 appears to cause a severe clinical picture in humans, ranging from mild malaise to death by sepsis/acute respiratory distress syndrome. The prognosis is worse in elderly patients with comorbidities. To date, there is no specific therapy for COVID-19. Prevention of SARS-CoV-2 infection implies strategies that limit the spread of the virus. WHO and other international and national bodies have developed continuously updated strategic objectives and provisions to contain the spread of the virus and infection.
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- 2020
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14. Impact of Pertussis on the Italian population: Analysis of hospital discharge records in the period 2001–2014
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Federica Brosio, Parvanè Kuhdari, Silvia Cocchio, Armando Stefanati, Vincenzo Baldo, and Giovanni Gabutti
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Infectious and parasitic diseases ,RC109-216 - Abstract
Objectives: The study aimed to analyze and update the impact of pertussis on the Italian population by evaluating pertussis-related hospital admissions in the period 2001–2014. Design or methods: Hospital Discharge Records (HDR) were provided by the National Archive of HDR data of the Ministry of Health. Only hospitalizations included in the primary diagnosis were evaluated. Significant trends over the considered years were assessed as average annual percent changes (AAPC) applying the Joinpoint model. Results: A total of 7,102 hospital admissions for pertussis (main diagnosis) were registered; the trend of hospitalizations progressively decreased from >1/100,000 inhabitants in the years 2001-2004 to 0.64/100,000 inhabitants in 2014. A great part of hospitalizations (63.6%) involved subjects
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- 2020
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15. A 2-year point-prevalence surveillance of healthcare-associated infections and antimicrobial use in Ferrara University Hospital, Italy
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Paola Antonioli, Niccolò Bolognesi, Giorgia Valpiani, Chiara Morotti, Daniele Bernardini, Francesca Bravi, Eugenio Di Ruscio, Armando Stefanati, and Giovanni Gabutti
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Infection control ,Cross infection ,Iatrogenic disease ,Antimicrobial stewardship ,Drug resistance, bacterial ,Point prevalence survey ,Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract Background Healthcare-Associated Infections (HAIs) represent one of the leading issues to patient safety as well as a significant economic burden. Similarly, Antimicrobial Use (AMU) and Resistance (AMR) represent a growing threat to global public health and the sustainability of healthcare services. Methods A Point Prevalence Survey (PPS) following the 2016 ECDC protocol for HAI prevalence and AMU was conducted at Ferrara University Hospital (FUH). Data were collected by a team of trained independent surveyors in 2016 and 2018. Risk factors independently associated with HAI were assessed by a multivariate logistic regression model. Results Of the 1102 patients surveyed, 115 (10.4%) had an active HAI and 487 (44.2%) were on at least 1 systemic antimicrobial agent. Factors independently associated with increased HAI risk were a “Rapidly Fatal” McCabe score (expected fatal outcome within 1 year), presence of medical devices (PVC, CVC, indwelling urinary catheter or mechanically assisted ventilation) and a length of hospital stay of at least 1 week. The most frequent types of HAI were pneumonia, bloodstream infections, and urinary tract infections. Antimicrobial resistance to third-generation cephalosporins was observed in about 60% of Enterobacteriaceae. Conclusions The survey reports a high prevalence of HAI and AMU in FUH. Repeated PPSs are useful to control HAIs and AMU in large acute-care hospitals, highlighting the main problematic factors and allowing planning for improvement actions.
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- 2020
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16. Viral Respiratory Infections in Hematological Patients
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Gabutti, Giovanni, De Motoli, Francesco, Sandri, Federica, Toffoletto, Maria Vittoria, and Stefanati, Armando
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- 2020
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17. Coronavirus: Update Related to the Current Outbreak of COVID-19
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Gabutti, Giovanni, d’Anchera, Erica, Sandri, Federica, Savio, Marta, and Stefanati, Armando
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- 2020
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18. Varicella zoster virus vaccines: an update
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Gabutti G, Bolognesi N, Sandri F, Florescu C, and Stefanati A
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EPIDEMIOLOGY ,VARICELLA VACCINE ,RECOMBINANT ZOSTER VACCINE ,ZOSTER VACCINE LIVE ,VACCINATION STRATEGIES ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Giovanni Gabutti,1 Niccolò Bolognesi,2 Federica Sandri,2 Caterina Florescu,2 Armando Stefanati11Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 2Postgraduate School of Hygiene and Preventive Medicine, University of Ferrara, Ferrara, ItalyAbstract: Varicella zoster virus (VZV) is the etiological agent of varicella, a highly infectious, self-limiting disease with serious complications. The decline in cell-mediated immunity (CMI) that occurs with aging or immunodepression causes a reactivation of the latent VZV as herpes zoster (HZ). Prevention of VZV through varicella vaccination strategies allows to avoid the primary infection in newborns and susceptible subjects. Available monovalent and combined VZV vaccines are effective, safe and generally well tolerated. Universal varicella vaccination has significantly impacted on incidence, complications and deaths related to this disease. Prevention of HZ through vaccination is a priority to avoid the significant burden of its incidence and complications. Currently two HZ vaccines are available. The recombinant zoster vaccine (RZV), approved by the FDA in 2017 and Zoster Vaccine Live (ZVL) licensed in the United States by the FDA in 2006. The advisory committee on immunization practices (ACIP) preferentially recommends RZV. ZVL remains an option for prevention of HZ in immunocompetent adults aged ≥60 years, although the CMI tends to wane a few years after vaccination.Keywords: epidemiology, varicella vaccine, recombinant zoster vaccine, Zoster Vaccine Live, vaccination strategies
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- 2019
19. Assessment of seroprevalence against poliovirus among Italian adolescents and adults
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Silvia Lupi, Armando Stefanati, Tatjana Baldovin, Alberto Roman, Vincenzo Baldo, and Giovanni Gabutti
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poliomyelitis ,seroprevalence ,immunity ,microneutralization assay ,seropositivity ,Immunologic diseases. Allergy ,RC581-607 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
In 2002, the WHO European Region was declared polio-free. Nonetheless global eradication has not yet been completed and the reintroduction from at risk areas is still possible. This seroprevalence study evaluated samples collected from each Italian region in the 12−50 years old age range to assess protection against Poliovirus (PV) 1, 2 and 3 among subjects immunised with different vaccination schedules. 1073 samples (50.5% females) were examined. WHO standardized microneutralization assay was used. Seroprotection rates were 92.9%, 96.2% and 83.4%, for PV1, PV2 and PV3, respectively. Geometric Mean Titres (GMTs) were higher for PV2 (52.8) and PV1 (41.1) than for PV3 (21.0). Increasing the age, a decreasing trend in seropositivity was observed, in particular for PV3. The 2017–2019 Italian National Immunisation Plan emphasises, as primary objective, the maintenance of the polio-free status and strongly validates the 2 + 1 schedule in the first year of life with IPV vaccine associated with the administration of booster doses at 6 years and during the adolescence. Surveillance system and high population immunity are crucial to ensure the maintenance of polio-free status.
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- 2019
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20. Attitudes towards compulsory vaccination in Italy: Results from the NAVIDAD multicentre study
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Castaldi, S., Di Donna, F., Di Martino, G., Genovese, C., Golfera, M., Gori, D., Greco, P., Loperto, I., Miduri, A., Olivero, E., Prospero, E., Quattrocolo, F., Rossello, P., Rosso, A., Sisti, L.G., Stracci, F., Zappalà, G., Gualano, M.R., Bert, F., Voglino, G., Buttinelli, E., D'Errico, M.M., De Waure, C., Di Giovanni, P., Fantini, M.P., Giuliani, A.R., Marranzano, M., Masanotti, G., Massimi, A., Nante, N., Pennino, F., Squeri, R., Stefanati, A., Signorelli, C., and Siliquini, R.
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- 2018
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21. Immunogenicity and safety of the multicomponent meningococcal B vaccine (4CMenB) in children and adolescents: a systematic review and meta-analysis
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Flacco, Maria Elena, Manzoli, Lamberto, Rosso, Annalisa, Marzuillo, Carolina, Bergamini, Mauro, Stefanati, Armando, Cultrera, Rosario, Villari, Paolo, Ricciardi, Walter, Ioannidis, John P A, and Contopoulos-Ioannidis, Despina G
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- 2018
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22. Influenza coverage rates in subjects with chronic heart diseases: results obtained in four consecutive immunisation seasons in the Local Health Unit of Ferrara (North Italy)”
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Stefanati, Armando, Lupi, Silvia, Campo, Gianluca, Cocchio, Silvia, Furlan, Patrizia, Baldo, Vincenzo, and Gabutti, Giovanni
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- 2020
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23. A novel nonlive, adjuvanted herpes zoster subunit vaccine: a report on the emerging clinical data and safety profile
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Brosio F, Masetti G, Matteo G, Stefanati A, and Gabutti G
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Herpes Zoster ,adjuvanted recombinant subunit Herpes Zoster vaccine ,live attenuated Herpes Zoster vaccine ,Infectious and parasitic diseases ,RC109-216 - Abstract
Federica Brosio,1 Giulia Masetti,1 Giulio Matteo,1 Armando Stefanati,2 Giovanni Gabutti2 1Postgraduate School of Hygiene and Preventive Medicine, Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 2Department of Medical Sciences, University of Ferrara, Ferrara, Italy Abstract: Herpes zoster (HZ) is an acute vesicular dermatitis with a typical dermatomal distribution, caused by the varicella zoster virus (VZV), often preceded and accompanied by prodromal pain or pruritus. HZ may be related to several complications such as postherpetic neuralgia (PHN). The incidence and severity of the disease increase with aging, due to immunosenescence and in particular to the decline of the specific cell-mediated immunity (CMI). The impact of HZ in terms of morbidity and short- and long-term complications, the availability of suboptimal treatment options to date, and the high costs for the diagnostic and clinical-therapeutic management of patients have motivated the search for a new preventive approach through the development of a vaccine. The vaccine currently in use with live-attenuated virus (ZVL) has been shown to be effective in reducing the incidence of HZ, its impact, and the onset of PHN, although the efficacy is lower in older subjects and tends to decrease some years after immunization. A new adjuvanted recombinant subunit vaccine (HZ/su), containing the VZV glycoprotein E (gE) and the AS01B adjuvant system, is now a very promising alternative to ZVL; in several clinical studies, it showed a good safety profile and was able to elicit high immune humoral and cell-mediated responses, both maintained up to 9 years. Furthermore, HZ/su vaccine was effective both in preventing HZ and in reducing the onset of PHN and other complications. HZ/su has been recommended and preferred over ZVL by the Advisory Committee on Immunization Practices (ACIP) for the prevention of HZ and its complications in immunocompetent adults aged ≥50 years, even if already vaccinated with ZVL, through a two-dose schedule. HZ/su has been approved in Canada, USA, Europe, and Japan and is currently being approved in Australia. The aim of this review was to describe the epidemiological data, HZ and PHN risks and their impact on the social life and common life of infected people, and ZVL and HZ/su vaccine development including various clinical trials and efficacy, safety, and tolerability profiles. Keywords: herpes zoster, adjuvanted recombinant herpes zoster subunit vaccine, live-attenuated herpes zoster vaccine
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- 2018
24. Human respiratory syncytial virus and hospitalization in young children in Italy
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Parvanè Kuhdari, Federica Brosio, Cristina Malaventura, Armando Stefanati, Andrea Orsi, Giancarlo Icardi, and Giovanni Gabutti
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Human respiratory syncytial virus ,Epidemiology ,Impact ,Hospitalization ,Pediatrics ,RJ1-570 - Abstract
Abstract Background Human respiratory syncytial virus (hRSV) is ubiquitous and causes respiratory diseases in both children and adults. Worldwide, hRSV pneumonia is the second cause of postnatal infant death after malaria. Given the high impact in terms of morbidity, mortality and costs, especially in the pediatric population, hRSV is recognized as a global health problem and the WHO, in view of the availability of new vaccines, has urged an active surveillance program of virus-related infections. The aim of this study has been to evaluate the impact of hRSV infections in the Italian population, particularly the pediatric one, in terms of hospitalizations. Methods In the period 2001–2014, Hospital Discharge Records (HDRs) with the following diagnosis codes included in the primary diagnosis were evaluated: 466.11 (hRSV bronchiolitis), 480.1 (hRSV pneumonia) and 796 (hRSV). HDRs were supplied by the National Archive of HDRs data, Ministry of Health. Results During the period 2001–2014, 57,656 hospital admissions due to hRSV pathologies were performed. Most hospitalizations (88.8%) involved patients with less than 1 year of age. Considering only primary diagnosis, 93% of the admissions were due to bronchiolitis, 5% to pneumonia and 2% to not otherwise specified hRSV infections. In the period 2001–2014, the hospitalization rate in 0–2 years old children, was equal to 224.8, 9.6 and 4.6/100,000 for hRSV bronchiolitis, hRSV pneumonia and not otherwise specified hRSV infection, respectively. Conclusions This study confirms the high impact of hRSV on the pediatric population in the age class 0–4 years, with a peak in the first 12 months of life. Most hospitalizations were urgent, although the duration of the hospital stay was for the most part less than a week, with ordinary discharge at home. Pending the conclusion of ongoing clinical trials on different hRSV vaccine types, it is extremely important to have updated data on the impact of hRSV-related pathologies in the various age groups.
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- 2018
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25. Human Papilloma Virus Vaccination: Focus on the Italian Situation
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Giovanni Gabutti, Erica d’Anchera, Francesco De Motoli, Marta Savio, and Armando Stefanati
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HPV ,HPV vaccination ,papilloma virus ,vaccines ,adolescents ,infectious diseases ,Medicine - Abstract
Human papilloma virus (HPV) is a viral agent whose transmission occurs mainly by sexual means. It causes different pathological conditions in both males and females, ranging from benign pathologies up to cancers. The introduction of vaccination has certainly had a major impact in terms of reducing the incidence of both HPV infections and diseases but in the European Union and the European Economic Area (EU/EEA) there are still about more than 13,000 deaths due to cervical cancer each year. To date in Europe and in Italy there are three vaccines available (bi-, tetra-, and nonvalent vaccines). The vaccination campaign started irregularly in Europe and Italy in 2007, with pre-adolescent girls as the primary target. Later, other cohorts were introduced such as 12-year-old boys, additional cohorts of >25-year-old women, women who already underwent cervical surgery and other subjects entitled to free vaccination. The COVID-19 pandemic has strongly impacted on public health services, particularly on vaccinations that, especially during the first pandemic phase, have been often delayed and/or canceled. The most affected vaccinations by the pandemic have been the non-mandatory ones, particularly those addressing the adolescent and adult population, such as immunization against papillomavirus. To date the achievement of the coverage target set by the Italian National Immunization Plan (NIP) has not yet been achieved. The aim of this work is to summarize the current situation in Italy and to discuss the strategies that have been implemented to increase overall vaccination coverage rates.
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- 2021
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26. An Unfitted Method with Elastic Bed Boundary Conditions for the Analysis of Heterogeneous Arterial Sections
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Gahima, Stephan, primary, Díez, Pedro, additional, Stefanati, Marco, additional, Rodríguez Matas, José Félix, additional, and García-González, Alberto, additional
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- 2023
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27. Sociomedical Indicators in the Cholera Epidemic in Ferrara of 1855
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Scapoli, Chiara, Guidi, Enrica, Angelini, Lauretta, Stefanati, Armando, and Gregorio, Pasquale
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- 2003
28. Diagnostic anticipation to reduce emergency department length of stay: a retrospective cohort study in Ferrara University hospital, Italy
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Strada, Andrea, Bolognesi, Niccolò, Manzoli, Lamberto, Valpiani, Giorgia, Morotti, Chiara, Bravi, Francesca, Bentivegna, Roberto, Forini, Elena, Pesci, Antonella, Stefanati, Armando, Di Ruscio, Eugenio, and Carradori, Tiziano
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- 2020
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29. A 2-year point-prevalence surveillance of healthcare-associated infections and antimicrobial use in Ferrara University Hospital, Italy
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Antonioli, Paola, Bolognesi, Niccolò, Valpiani, Giorgia, Morotti, Chiara, Bernardini, Daniele, Bravi, Francesca, Di Ruscio, Eugenio, Stefanati, Armando, and Gabutti, Giovanni
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- 2020
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30. Has VZV epidemiology changed in Italy? Results of a seroprevalence study
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Antonella De Donno, Parvanè Kuhdari, Marcello Guido, Maria Cristina Rota, Antonino Bella, Giordana Brignole, Silvia Lupi, Adele Idolo, Armando Stefanati, Martina Del Manso, Giovanni Gabutti, and The Study Group on seroepidemiology
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chickenpox ,immunization ,seroprevalence ,surveillance ,varicella-zoster virus ,Immunologic diseases. Allergy ,RC581-607 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
The aim of the study was to evaluate if and how varicella prevalence has changed in Italy. In particular a seroprevalence study was performed, comparing it to similar surveys conducted in pre-immunization era. During 2013–2014, sera obtained from blood samples taken for diagnostic purposes or routine investigations were collected in collaboration with at least one laboratory/center for each region, following the approval of the Ethics Committee. Data were stratified by sex and age. All samples were processed in a national reference laboratory by an immunoassay with high sensitivity and specificity. Statutory notifications, national hospital discharge database and mortality data related to VZV infection were analyzed as well. A total of 3707 sera were collected and tested. In the studied period both incidence and hospitalization rates decreased and about 5 deaths per year have been registered. The seroprevalence decreased in the first year of life in subjects passively protected by their mother, followed by an increase in the following age classes. The overall antibody prevalence was 84%. The comparison with surveys conducted with the same methodology in 1996–1997 and 2003–2004 showed significant differences in age groups 1–19 y. The study confirms that in Italy VZV infection typically occurs in children. The impact of varicella on Italian population is changing. The comparison between studies performed in different periods shows a significant increase of seropositivity in age class 1 – 4 years, expression of vaccine interventions already adopted in some regions.
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- 2017
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31. COVID-19: opinions and behavior of Italian general population during the first epidemic phase
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Genovese, C., La Fauci, V., Di Pietro, A., Trimarchi, G., Odone, A., Casuccio, A., Costantino, C., Restivo, V., Fantini, M., Gori, D., Azzara, A., Deiana, G., Castaldi, S., Righi, E., Palandri, L., Panciroli, G., Bianco, A., Licata, F., Cosentino, S., Mistretta, A., Marranzano, M., Ragusa, R., Gabutti, G., Stefanati, A., Prato, R., Fortunato, F., Martinelli, D., Icardi, G., Panatto, D., Amicizia, D., Fabiani, L., Moretti, A., Di Risio, D., Siliquini, R., Voglino, G., Bert, F., Lorini, C., Bonaccorsi, G., Torre, I., Pennino, F., Pavia, M., Di Giuseppe, G., Paolantonio, A., Villari, P., Marzuillo, C., Messina, G., Rivieri, C., Nante, N., Majori, S., Tardivo, S., Moretti, F., D'Amato, S., Mazzitelli, F., Giunta, I., Lo Giudice, D., Panto, G., Signorelli, C., Squeri, R., Genovese, Cristina, La Fauci, Vincenza, Di Pietro, Angela, Trimarchi, Giuseppe, Odone, Anna, Casuccio, Alessandra, Costantino, Claudio, Restivo, Vincenzo, Fantini, Mariapia, Gori, Davide, Azara, Antonio, Deiana, Giovanna, Castaldi, Silvana, Righi, Elena, Palandri, Lucia, Panciroli, Giovanni, Bianco, Aida, Licata, Francesca, Cosentino, Sofia, Mistretta, Antonio, Marranzano, Marina, Ragusa, Rosalia, Gabutti, Giovanni, Stefanati, Armando, Prato, Rosa, Fortunato, Francesca, Martinelli, Domenico, Icardi, Giancarlo, Panatto, Donatella, Amicizia, Daniela, Fabiani, Leila, Moretti, Annalucia, Di Risio, Damiana, Siliquini, Roberta, Voglino, Gianluca, Bert, Fabrizio, Lorini, Chiara, Bonaccorsi, Guglielmo, Torre, Ida, Pennino, Francesca, Pavia, Maria, Di Giuseppe, Gabriella, Paolantonio, Andrea, Villari, Paolo, Marzuillo, Carolina, Messina, Gabriele, Rivieri, Cesare, Nante, Nicola, Majori, Silvia, Tardivo, Stefano, Moretti, Francesca, D'Amato, Smeralda, Mazzitelli, Francesco, Giunta, Ioselita, Lo Giudice, Daniela, Pantò, Giuseppe, Signorelli, Carlo, Squeri, Raffaele, Genovese C., La Fauci V., Di Pietro A., Trimarchi G., Odone A., Casuccio A., Costantino C., Restivo V., Fantini M., Gori D., Azzara A., Deiana G., Castaldi S., Righi E., Palandri L., Panciroli G., Bianco A., Licata F., Cosentino S., Mistretta A., Marranzano M., Ragusa R., Gabutti G., Stefanati A., Prato R., Fortunato F., Martinelli D., Icardi G., Panatto D., Amicizia D., Fabiani L., Moretti A., Di Risio D., Siliquini R., Voglino G., Bert F., Lorini C., Bonaccorsi G., Torre I., Pennino F., Pavia M., Di Giuseppe G., Paolantonio A., Villari P., Marzuillo C., Messina G., Rivieri C., Nante N., Majori S., Tardivo S., Moretti F., D'amato S., Mazzitelli F., Giunta I., Lo Giudice D., Panto G., Signorelli C., and Squeri R.
- Subjects
risk perception ,Male ,knowledge ,SARS-CoV-2 ,attitude ,COVID-19 ,perception ,population ,attitude, COVID-19, knowledge, perception, population, risk perception ,Attitude ,Humans ,Female ,Public Health ,Epidemics ,Human - Abstract
Background and aim: On January 9, 2020, the World Health Organization (WHO) declared that Chinese health authorities had identified a new coronavirus strain never before isolated in humans, the 2019-nCoV later redefined SARS-CoV-2, that still today represent a public health problem. The present survey started on 10 February 2020 with the aim of a) assessing the risk perception in healthcare workers and young students, following the evolution of attitudes, perception and knowledge over time, b) provide useful information to the general population during survey. Results: A study sample consisting of 4116 Italian in-dividuals of both sexes was enrolled. High levels of risk perception, low perception of self-efficacy and low levels of knowledge scores (24.55 ± 5.76 SD) were obtained indicating the need for continuous population monitoring as well as further communication strategies carried out at institution levels. Conclusion: The results of the present study could help public health authorities in carrying out informative campaigns for general population and could be an important tool in evaluating public knowledge and misperceptions during the management of the COVID-19. (www.actabiomedica.it).
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- 2022
32. Cholera, the Current Status of Cholera Vaccines and Recommendations for Travellers
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Giovanni Gabutti, Andrea Rossanese, Alberto Tomasi, Sandro Giuffrida, Vincenzo Nicosia, Juan Barriga, Caterina Florescu, Federica Sandri, and Armando Stefanati
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cholera ,cholera prevention ,vaccines ,oral cholera vaccine ,Medicine - Abstract
Cholera is endemic in approximately 50 countries, primarily in Africa and South and Southeast Asia, and in these areas, it remains a disease associated with poverty. In developed nations, cholera is rare, and cases are typically imported from endemic areas by returning travellers. Cholera is readily preventable with the tools available to modern medicine. In developing nations, cholera transmission can be prevented through improved water, sanitation, and hygiene services and the use of oral cholera vaccines (OCVs). For travellers, risk can be mitigated by practicing regular hand hygiene and consuming food and water from safe sources. OCVs should be considered for high-risk travellers likely to be exposed to cholera patients or contaminated water and food. There are currently three World Health Organization pre-qualified OCVs, which are based on killed whole-cell strains of Vibrio cholerae. These established vaccines offer significant protection in adults and children for up to 2 years. A novel live attenuated vaccine that provides rapid-onset protection in adults and children is licensed in the USA and Europe only. Live attenuated OCVs may mimic the natural infection of V. cholerae more closely, generating rapid immune responses without the need for repeat dosing. These potential benefits have prompted the ongoing development of several additional live attenuated vaccines. The objective of this article is to provide a general review of the current landscape of OCVs, including a discussion of their appropriate use in international travellers.
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- 2020
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33. Pertussis Immunization in Pregnancy: A Review
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Gabutti, Giovanni, primary, Stefanati, Armando, additional, and Kuhdari, Parvanè, additional
- Published
- 2018
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34. Identifying elderly with low vaccine uptake using social deprivation indices: a systematic review: Vladimir Vukovic
- Author
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Vukovic, V, Gasparini, R, Amicizia, D, Arata, L, Boccalini, S, Fortunato, F, Lillini, R, Panatto, D, Stefanati, A, and de Waure, C
- Published
- 2017
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35. Immunogenicity and safety of the multicomponent meningococcal B vaccine (4CMenB): a meta-analysis: Lamberto Manzoli
- Author
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Flacco, ME, Manzoli, L, Rosso, A, Marzuillo, C, Bergamini, M, Stefanati, A, Villari, P, Ricciardi, W, Ioannidis, JP, and Contopoulos-Ioannidis, DG
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- 2017
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36. Temporal trends in herpes zoster-related hospitalizations in Italy, 2001–2013: differences between regions that have or have not implemented varicella vaccination
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Valente, Nicoletta, Cocchio, Silvia, Stefanati, Armando, Baldovin, Tatjana, Martinelli, Domenico, Prato, Rosa, Baldo, Vincenzo, and Gabutti, Giovanni
- Published
- 2017
- Full Text
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37. Ceftolozane/Tazobactam and Ceftazidime/Avibactam for Multidrug-Resistant Gram-Negative Infections in Immunocompetent Patients: A Single-Center Retrospective Study
- Author
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Rosario Cultrera, Marco Libanore, Agostino Barozzi, Erica d’Anchera, Letizia Romanini, Fabio Fabbian, Francesco De Motoli, Brunella Quarta, Armando Stefanati, Niccolò Bolognesi, and Giovanni Gabutti
- Subjects
carbapenem-sparing regimen ,ceftazidime/avibactam ,ceftolozane-tazobactam ,ESBL-producing Enterobacterales ,healthcare-associated infections ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Complicated infections from multidrug-resistant Gram-negative bacteria (MDR-GNB) represent a serious problem presenting many challenges. Resistance to many classes of antibiotics reduces the probability of an adequate empirical treatment, with unfavorable consequences, increasing morbidity and mortality. Readily available patient medical history and updated information about the local microbiological epidemiology remain critical for defining the baseline risk of MDR-GNB infections and guiding empirical treatment choices, with the aim of avoiding both undertreatment and overtreatment. There are few literature data that report real-life experiences in the use of ceftolozane/tazobactam and ceftazidime/avibactam, with particular reference to microbiological cure. Some studies reported experiences for the treatment of MDR-GNB infections in patients with hematological malignancies or specifically in Pseudomonas aeruginosa infections. We report our clinical single-center experience regarding the real-life use of ceftolozane/tazobactam and ceftazidime/avibactam to treat serious and complicated infections due to MDR-GNB and carbapenem-resistant Enterobacterales (CRE), with particular regard given to intra-abdominal and urinary tract infections and sepsis.
- Published
- 2020
- Full Text
- View/download PDF
38. Assessment of Malnutrition in Community-dwelling Elderly People: Cooperation among General Practitioners and Public Health
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Maura FERRARI BRAVO, Fabrizio GALLO, Concetta MARCHELLO, Roberta BOICELLI, Silvia LUPI, Massimiliano ATZEI, Francesco BRUNETTI, Romina CASARETTO, Federico DAPELO, Daniela GEREVINI, Eliana LEONARDELLI, Anna MANNO, Elisabetta PERI, Paola SOAVE, Angelo TRAVERSARO, Antonio ZAMPOGNA, Roberto ZUNINO, Armando STEFANATI, and Giovanni GABUTTI
- Subjects
Malnutrition ,Free-living elderly people ,MNA ,Dietetic counseling ,Public aspects of medicine ,RA1-1270 - Abstract
Background: Malnutrition, a very common condition in the elderly, is known to increase their vulnerability to adverse health events. This study aimed to estimate the prevalence of malnutrition in the over 75-yr-old community-dwelling population in the “Chiavarese” Local Health Unit district (North West Italy). Methods: The short version of the Mini Nutritional Assessment (MNA-SF) was used by General Practitioners (GP) as a screening tool to investigate the nutritional status of elderly people (1039 subjects). The study was conducted in 2012- 2013 in the Local Health Unit of Chiavari (Liguria Region), Italy. The malnutrition was subsequently confirmed by means of biochemical parameters. Subjects at risk of malnutrition or malnourished (n=22) received personalized dietary counseling by the GP. Results: The MNA-SF recognized 21% of the elderly people being at risk of malnutrition and biochemical tests confirmed a malnutrition prevalence of 3.5%. The dietary counseling improved the MNA-SF score and biochemical parameters, but the difference was statistically significant only for the MNA-SF score (P=0.00613). Conclusion: Malnutrition can be evaluated with a simple tool such as the MNA-SF, recognized at the earliest stage and successfully treated by the GP.
- Published
- 2018
39. A Knowledge, Attitude, and Perception Study on Flu and COVID-19 Vaccination during the COVID-19 Pandemic: Multicentric Italian Survey Insights
- Author
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Genovese, Cristina, Costantino, Claudio, Odone, Anna, Trimarchi, Giuseppe, La Fauci Vincenza, Mazzitelli, Francesco, D'Amato, Smeralda, Squeri, Raffaele, The Covid-Risk Perception Group (Alessandra Casuccio, Maria Pia Fantini, Antonio, Azara, Silvana, Castaldi, Righi, Elena, Aida, Bianco, Sofia, Cosentino, Antonio, Mistretta, Giovanni, Gabutti, Rosa, Prato, Giancarlo, Icardi, Leila, Fabiani, Roberta, Siliquini, Guglielmo, Bonaccorsi, Ida, Torre, Maria, Pavia, Paolo, Villari, Gabriele, Messina, Silvia, Majori, Vincenzo, Restivo, Davide, Gori, Giovanna, Deiana, Palandri, Lucia, Panciroli, Giovanni, Francesca, Licata, Marina, Marranzano, Armando, Stefanati, Francesca, Fortunato, Domenico, Martinelli, Donatella, Panatto, Daniela, Amicizia, Annalucia, Moretti, Damiana Di Risio, Gianluca, Voglino, Fabrizio, Bert, Chiara, Lorini, Francesca, Pennino, Gabriella Di Giuseppe, Andrea, Carolina, Marzuillo, Cesare, Rivieri, Nicola, Nante, Stefano, Tardivo, Francesca, Moretti, Rosalia, Ragusa, Carlo, Signorelli), C., Genovese, C., Costantino, A., Odone, G., Trimarchi, V., La Fauci, F., Mazzitelli, S., D'Amato, R., Squeri, Casuccio, Alessandra, Pia Fantini, Maria, Azara, Antonio, Castaldi, Silvana, Righi, Elena, Bianco, Aida, Cosentino, Sofia, Mistretta, Antonio, Gabutti, Giovanni, Prato, Rosa, Icardi, Giancarlo, Fabiani, Leila, Siliquini, Roberta, Bonaccorsi, Guglielmo, Torre, Ida, Pavia, Maria, Villari, Paolo, Messina, Gabriele, Majori, Silvia, Restivo, Vincenzo, Gori, Davide, Deiana, Giovanna, Palandri, Lucia, Panciroli, Giovanni, Licata, Francesca, Marranzano, Marina, Stefanati, Armando, Fortunato, Francesca, Martinelli, Domenico, Panatto, Donatella, Amicizia, Daniela, Moretti, Annalucia, Di Risio, Damiana, Voglino, Gianluca, Bert, Fabrizio, Lorini, Chiara, Pennino, Francesca, Di Giuseppe, Gabriella, Andrea, Marzuillo, Carolina, Rivieri, Cesare, Nante, Nicola, Tardivo, Stefano, Moretti, Francesca, Ragusa, Rosalia, Signorelli., Carlo, Genovese C., Costantino C., Odone A., Trimarchi G., La Fauci V., Mazzitelli F., D'amato S., and Squeri R.
- Subjects
Pharmacology ,knowledge ,attitudes ,COVID-19 vaccination ,Vaccination ,Immunology ,COVID-19 ,flu vaccination ,perception ,vaccination ,Knowledge ,Infectious Diseases ,Attitude ,Attitudes ,Drug Discovery ,Perception ,Pharmacology (medical) ,Flu vaccination - Abstract
In January 2020, Chinese health authorities identified a novel coronavirus strain never before isolated in humans. It quickly spread across the world, and was eventually declared a pandemic, leading to about 310 million confirmed cases and to 5,497,113 deaths (data as of 11 January 2022). Influenza viruses affect millions of people during cold seasons, with high impacts, in terms of mortality and morbidity. Patients with comorbidities are at a higher risk of acquiring severe problems due to COVID-19 and the flu—infections that could impact their underlying clinical conditions. In the present study, knowledge, attitudes, and opinions of the general population regarding COVID-19 and influenza immunization were evaluated. A multicenter, web-based, cross-sectional study was conducted between 10 February and 12 July 2020, during the first wave of SARS-CoV-2 infections among the general population in Italy. A sample of 4116 questionnaires was collected at the end of the study period. Overall, 17.5% of respondents stated that it was unlikely that they would accept a future COVID-19 vaccine (n = 720). Reasons behind vaccine refusal/indecision were mainly a lack of trust in the vaccine (41.1%), the fear of side effects (23.4%), or a lack of perception of susceptibility to the disease (17.1%). More than 50% (53.8%; n = 2214) of the sample participants were willing to receive flu vaccinations in the forthcoming vaccination campaign, but only 28.2% of cases had received it at least once in the previous five seasons. A higher knowledge score about SARS-CoV-2/COVID-19 and at least one flu vaccination during previous influenza seasons were significantly associated with the intention to be vaccinated against COVID-19 and influenza. The continuous study of factors, determining vaccination acceptance and hesitancy, is fundamental in the current context, in regard to improve vaccination confidence and adherence rates against vaccine preventable diseases.
- Published
- 2022
40. Assessment of lifestyle and eating habits among undergraduate students in northern Italy
- Author
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Silvia Lupi, Francesco Bagordo, Armando Stefanati, Tiziana Grassi, Lucia Piccinni, Mauro Bergamini, and Antonella De Donno
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dietary habits ,university students ,food frequency questionnaire ,Public aspects of medicine ,RA1-1270 - Abstract
AIM AND METHODOLOGY: Dietary habits of university students were analyzed in order to investigate any differences between students living at and away from home. Two hundred and fifty-eight undergraduate students attending University of Ferrara completed a self-administered questionnaire on demographic characteristics, food frequency consumption habits and body weight perception. RESULTS: Students living at home practiced more sport and consumed more frequently raw and cooked vegetables, fish, meat and poultry, fresh fruit, eggs, bread/cereals. Conversely, students living away from home consumed more often packaged/ready food, beer and spirits, milk and chips. The majority of students living alone reported a modification of dietary habits since leaving family. Furthermore they perceived to have a weight condition different from normal in a greater extent than students living with family. DISCUSSION: Students living alone encountered more difficulties in adopting a healthy diet so it would be desirable to adopt nutritional educational interventions on university students, usually neglected by these measures.
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- 2015
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41. Travellers’ risk behaviors and health problems: Post-travel follow up in two travel medicine centers in Italy
- Author
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Valeria Baccello, A. Stano, Giovanni Gabutti, Vincenzo Baldo, Diego Gamberoni, Federica Sandri, P. Coin, A. Pierobon, E. DeStefani, Armando Stefanati, and Patrizia Furlan
- Subjects
Adult ,Diarrhea ,Male ,Street vendor ,medicine.medical_specialty ,Adolescent ,Fever ,Health Behavior ,Chemoprevention ,NO ,Young Adult ,03 medical and health sciences ,Health problems ,Travel-related health problems ,Risk-Taking ,Risk Factors ,Surveys and Questionnaires ,Environmental health ,medicine ,Humans ,Travel medicine ,dangerous behavior ,travel medicine ,travel-associated infectious diseases ,travel-related health problems ,travel-related illness ,Dangerous behavior ,Travel ,0303 health sciences ,030306 microbiology ,business.industry ,Vaccination ,Risk behavior ,people.profession ,Febrile illness ,Dangerous behavior, Travel medicine, Travel-associated infectious diseases, Travel-related health problems, Travel-related illness ,Middle Aged ,Middle age ,Skin reaction ,Infectious Diseases ,Italy ,Travel-associated infectious diseases ,Multivariate Analysis ,Female ,Travel-Related Illness ,people ,business ,human activities ,Travel Medicine ,Follow-Up Studies - Abstract
Objectives We examined the association between travellers’ characteristics, compliance with pre-travel recommendations and health problems. Methods Volunteer travellers were enrolled and data collected using a questionnaire between 30–60 days after returning home. We analyzed the associations through bivariate and multivariate models. Results Of the 468 enrolled travelers, 68% consumed raw food and 81% food containing milk and/or eggs. 32% consumed street vendor food and 30% drinks containing ice. 24% used the recommended mechanical prophylaxis measures. 46% got sick during and/or after travel (gastrointestinal symptoms most frequently). Factors predisposing to health problems were female gender, youth/middle age, intermediate travel duration and profession. The American continent and staying in hostels and tents were significantly associated with febrile illness. Street vendor food was significantly associated with skin reactions. Conclusions Adherence to behavioral recommendations remains low. Travellers must be informed of health risks during and after travel.
- Published
- 2021
42. Human respiratory syncytial virus and hospitalization in young children in Italy
- Author
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Kuhdari, Parvanè, Brosio, Federica, Malaventura, Cristina, Stefanati, Armando, Orsi, Andrea, Icardi, Giancarlo, and Gabutti, Giovanni
- Published
- 2018
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43. Chronic diseases are strongly associated with sickness absences in a sample of Italian public employees
- Author
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Enrico Casimirri, Alice Vaccari, Michela Schito, Melissa Bonci, Mariarita Stendardo, Armando Stefanati, Marco Nardini, and Piera Boschetto
- Subjects
sickness absence ,Chronic diseases ,occupational health ,gastrointestinal diseases ,psychiatric diseases ,Medicine - Abstract
Objectives: Data on the prevalence of chronic diseases and their relationship with sickness absence in the Italian public employees are rather scarce. Therefore, in the first place, we assessed the distribution of chronic diseases in the employees of the University of Ferrara. As a next step, we investigated the possible associations between each chronic disease and cumulative days of all-cause sickness absence, and finally we investigated the odds ratio of each single chronic disease on sickness absence. Material and Methods: A total of 514 employees, 269 sick-listed and 245 not sick-listed in 2012, were studied. Demographical/clinical characteristics and chronic diseases were obtained from all study participants during medical surveillance procedures. Sickness absence days and job seniority data were obtained from the administrative office. Results: Gastrointestinal and psychiatric diseases were the most reported in the sick-listed sample (p = 0.01 and p = 0.02, respectively, compared to the not sick-listed). In the interquantile regression analysis, the sickness absence days were as - sociated with psychiatric diseases (β = 65.1, 95% CI: 13.2-117.1, p = 0.01) and with the presence of 2 or more chronic diseases (β = 23.3, 95% CI: 4.5-42, p = 0.02). Furthermore, the logistic regression analysis showed that the odds of sickness absence were increased 2 fold by psychiatric diseases (OR = 2.2, 95% CI: 1.01-4.93, p = 0.04), and gastrointestinal diseases (OR = 1.9, 95% CI:1.07-3.42, p = 0.02) and, to a lesser extent, by high body mass index (OR = 1.05, 95% CI: 1-1.11, p = 0.03). Conversely, female gender reduced by half the odds of sickness absence (OR = 0.5, 95% CI: 0.3-0.8, p = 0.04). Conclusions: This study highlights the relevant association between chronic diseases and sickness absence in Italian public employees. Our findings indicate the importance of considering the health status when designing preventive interventions aimed at decreasing sickness absences in this population.
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- 2014
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44. Sieroprevalenza della pertosse nella popolazione italiana: risultati preliminari
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Tiziana, Grassi, Savio, Marta, Francesco, Bagordo, Maria Cristina, Rota, Panico, A., DE MOTOLI, Francesco, Lupi, Silvia, Stefanati, Armando, Gabutti, Giovanni, and Gruppo di studio Sieroepidemiologia
- Subjects
NO - Published
- 2022
45. Viral Respiratory Infections in Hematological Patients
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Francesco De Motoli, Maria Vittoria Toffoletto, Federica Sandri, Armando Stefanati, and Giovanni Gabutti
- Subjects
0301 basic medicine ,Microbiology (medical) ,Respiratory viral infections ,medicine.medical_specialty ,030106 microbiology ,Review ,Infectious and parasitic diseases ,RC109-216 ,medicine.disease_cause ,Virus ,NO ,03 medical and health sciences ,0302 clinical medicine ,Hematological malignancy ,Epidemiology ,Cancer, Hematological malignancy, Immunocompromised, Respiratory viral infections, Stem cell transplantation ,medicine ,030212 general & internal medicine ,Respiratory system ,Intensive care medicine ,Immunocompromised ,Cancer ,business.industry ,Incidence (epidemiology) ,Stem cell transplantation ,medicine.disease ,Infectious Diseases ,Rhinovirus ,business - Abstract
Viral infections of the respiratory system represent one of the most important complications in hematological patients in terms of both the severity of the clinical picture and its related impact on the duration of hospitalization, and of mortality. The most implicated viruses are those that commonly cause community-based respiratory diseases: respiratory syncytial virus, Influenza virus and rhinovirus. However, in some cases the clinical picture may be triggered by first infection with or reactivation of pathogens normally not responsible for clinically relevant diseases in immunocompetent subjects. This issue is currently being taken into greater consideration within the scientific community. However, the strong heterogeneity in the epidemiology and clinical expression of these infections and the lack of adequate therapeutic options imply that there is currently no uniform consensus on the best management of these patients. The main purpose of this review is to highlight which viruses are currently most implicated in the onset of these infections, what is their incidence in so heterogeneous and fragile patients and the factors that lead to disease's onset and evolution. Possible or available clinical management options, diagnostic and therapeutic tools, and preventive and prophylaxis measures are also discussed.
- Published
- 2020
46. Impact of Pertussis on the Italian population: Analysis of hospital discharge records in the period 2001–2014
- Author
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Parvanè Kuhdari, Silvia Cocchio, Vincenzo Baldo, Giovanni Gabutti, Federica Brosio, and Armando Stefanati
- Subjects
Adult ,Male ,0301 basic medicine ,Microbiology (medical) ,Adolescent ,Whooping Cough ,030106 microbiology ,Burden ,NO ,lcsh:Infectious and parasitic diseases ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Pertussis ,Pertussis-related hospitalization ,Hospital discharge ,Humans ,Medicine ,lcsh:RC109-216 ,030212 general & internal medicine ,Child ,Aged ,Aged, 80 and over ,Main diagnosis ,Joinpoint Model ,business.industry ,Vaccination ,Infant ,Pertussis, Burden, Vaccination, Pertussis-related hospitalization, Hospital discharge record ,General Medicine ,Middle Aged ,Italian population ,Patient Discharge ,Hospital discharge record ,The primary diagnosis ,Hospitalization ,Infectious Diseases ,Italy ,Child, Preschool ,Female ,Christian ministry ,business ,Demography - Abstract
Objectives: The study aimed to analyze and update the impact of pertussis on the Italian population by evaluating pertussis-related hospital admissions in the period 2001–2014. Design or methods: Hospital Discharge Records (HDR) were provided by the National Archive of HDR data of the Ministry of Health. Only hospitalizations included in the primary diagnosis were evaluated. Significant trends over the considered years were assessed as average annual percent changes (AAPC) applying the Joinpoint model. Results: A total of 7,102 hospital admissions for pertussis (main diagnosis) were registered; the trend of hospitalizations progressively decreased from >1/100,000 inhabitants in the years 2001-2004 to 0.64/100,000 inhabitants in 2014. A great part of hospitalizations (63.6%) involved subjects
- Published
- 2020
47. Cineamatori militanti
- Author
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Michele Ronchi Stefanati
- Subjects
Ghirri ,consumérisme ,impegno politico ,documentaires ,Language and Literature ,éthique ,consumismo ,etica ,engagement politique ,documentari - Abstract
Cet essai explore la relation entre l’œuvre cinématographique de Celati et la société contemporaine. Il s’agit de souligner que ses documentaires, comme ses textes, naissent d’une opposition évidente contre certains phénomènes qui caractérisent les sociétés contemporaines : les effets du consumérisme sur les rapports humains et sur l’environnement ; l’américanisation des habitudes ; le « maquillage » des effets du temps et de l’idée de la mort grâce à la chirurgie esthétique ; l’attitude néocolonialiste du tourisme en Afrique. Questo saggio indaga il legame tra l’opera cinematografica di Celati e la società contemporanea, sottolineando come i suoi documentari nascano sempre, come del resto i suoi scritti, da una netta contrapposizione a fenomeni pervasivi della contemporaneità quali gli effetti del consumismo sulle relazioni umane e sull’ambiente, l’americanizzazione dei costumi, la cancellazione degli effetti del tempo e dell’idea della morte tramite forme di chirurgia cosmetica, l’attitudine neocoloniale del turista occidentale in Africa.
- Published
- 2021
48. Human Papilloma Virus Vaccination: Focus on the Italian Situation
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Francesco De Motoli, Marta Savio, Erica d’Anchera, Giovanni Gabutti, and Armando Stefanati
- Subjects
medicine.medical_specialty ,HPV ,HPV, HPV vaccination, papilloma virus, vaccines, adolescents, infectious diseases, cervical cancer, COVID-19 ,cervical cancer ,Immunology ,Review ,infectious diseases ,NO ,Drug Discovery ,Pandemic ,medicine ,media_common.cataloged_instance ,Pharmacology (medical) ,adolescents ,European union ,media_common ,Pharmacology ,Cervical cancer ,HPV vaccination ,Transmission (medicine) ,business.industry ,Incidence (epidemiology) ,Public health ,COVID-19 ,vaccines ,medicine.disease ,Vaccination ,Immunization ,Medicine ,business ,Demography ,papilloma virus - Abstract
Human papilloma virus (HPV) is a viral agent whose transmission occurs mainly by sexual means. It causes different pathological conditions in both males and females, ranging from benign pathologies up to cancers. The introduction of vaccination has certainly had a major impact in terms of reducing the incidence of both HPV infections and diseases but in the European Union and the European Economic Area (EU/EEA) there are still about more than 13,000 deaths due to cervical cancer each year. To date in Europe and in Italy there are three vaccines available (bi-, tetra-, and nonvalent vaccines). The vaccination campaign started irregularly in Europe and Italy in 2007, with pre-adolescent girls as the primary target. Later, other cohorts were introduced such as 12-year-old boys, additional cohorts of >25-year-old women, women who already underwent cervical surgery and other subjects entitled to free vaccination. The COVID-19 pandemic has strongly impacted on public health services, particularly on vaccinations that, especially during the first pandemic phase, have been often delayed and/or canceled. The most affected vaccinations by the pandemic have been the non-mandatory ones, particularly those addressing the adolescent and adult population, such as immunization against papillomavirus. To date the achievement of the coverage target set by the Italian National Immunization Plan (NIP) has not yet been achieved. The aim of this work is to summarize the current situation in Italy and to discuss the strategies that have been implemented to increase overall vaccination coverage rates.
- Published
- 2021
49. Human Papilloma Virus Vaccination: Focus on the Italian Situation
- Author
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Gabutti, Giovanni, primary, d’Anchera, Erica, additional, De Motoli, Francesco, additional, Savio, Marta, additional, and Stefanati, Armando, additional
- Published
- 2021
- Full Text
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50. Evaluation and review of preventive measures applied during COVID-19 pandemic: strategies adopted by European countries
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Stefanati, Armando, D'Anchera, Erica, De Motoli, Francesco, Savio, Marta, Toffoletto, Maria Vittoria, and Gabutti, Giovanni
- Subjects
Europe ,Sars-CoV-2 ,Preventive measures ,COVID-19 pandemic ,Review ,Strategies - Abstract
The COVID-19 pandemic has greatly jeopardized the European continent and the spread of SARS-COV-2 has led European countries to implement a series of preventive interventions aimed at decreasing the incidence rate of the disease, in consideration of the lack of specific therapies and of a vaccine. Each European country has behaved in different ways and timing accordingly to the epidemiological trend and to different political strategies. The main purpose of preventive measures is to lower the incidence rate of the disease, avoiding the collapse of health systems and limiting the total number of severe cases and deaths. All these targets should fit with needs that go beyond scientific evidence such as economic interests, decisions of neighboring countries and specific socio-political factors for each country. The objective of this research is to clarify which preventive measures have been recommended and applied in different European countries., Journal of Preventive Medicine and Hygiene, Vol. 62 No. 1s3 (2021): SARS-CoV-2 (Covid-19) in the history of the pandemics: a tsunami that is changing the world
- Published
- 2021
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