1. Weight loss–induced reduction in physical activity recovers during weight maintenance
- Author
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Klaas R. Westerterp, Stefan Gja Camps, Sanne P. M. Verhoef, Humane Biologie, and RS: NUTRIM - R1 - Metabolic Syndrome
- Subjects
Adult ,Male ,DOUBLY-LABELED WATER ,medicine.medical_specialty ,BODY-COMPOSITION ,Diet, Reducing ,food.diet ,Physical Exertion ,Physical activity ,Medicine (miscellaneous) ,Body Mass Index ,Animal science ,food ,Weight loss ,Weight maintenance ,Weight Loss ,Humans ,Medicine ,Obesity ,LEAN MEN ,Caloric Restriction ,OVERWEIGHT ,Nutrition and Dietetics ,business.industry ,Body Weight ,ADAPTIVE THERMOGENESIS ,Thermogenesis ,Middle Aged ,medicine.disease ,Diet ,AFFLUENT SOCIETIES ,Surgery ,Very low calorie diet ,METABOLIC-RATE ,HUMAN ENERGY-EXPENDITURE ,Basal metabolic rate ,Body Composition ,SKELETAL-MUSCLE ,Female ,Basal Metabolism ,medicine.symptom ,Energy Intake ,Energy Metabolism ,Sleep ,business ,Body mass index ,RESTRICTION - Abstract
BACKGROUND: Weight loss due to a negative energy balance is considered to be accompanied by a decrease in physical activity. OBJECTIVE: The aim of this study was to investigate whether a decrease in physical activity is sustained during weight maintenance. DESIGN: Subjects were 20 men and 31 women [mean (+/-SD) age: 42 +/- 8 y; BMI (in kg/m2): 31.4 +/- 2.8]. Weight loss was achieved by an 8-wk very-low-energy diet period, followed by 44 wk of weight maintenance. Physical activity measures were total energy expenditure expressed as a multiple of sleeping metabolic rate (PALSMR) and resting metabolic rate (PALRMR), activity-induced energy expenditure divided by body weight (AEE/kg), and activity counts measured by a triaxial accelerometer. Measurements took place at 0, 8, and 52 wk. RESULTS: Body mass decreased significantly during the diet period (10.5 +/- 3.8%, P < 0.001), and this reduction was sustained after 52 wk (6.0 +/- 5.1%, P < 0.001). PALSMR and PALRMR decreased from 1.81 +/- 0.23 and 1.70 +/- 0.22, respectively, before the diet to 1.69 +/- 0.20 and 1.55 +/- 0.19 after the diet (P < 0.001) and increased again after weight maintenance to 1.85 +/- 0.27 and 1.71 +/- 0.23, respectively, compared with 8-wk measurements (P < 0.001). AEE/kg decreased from 0.043 +/- 0.015 MJ/kg at baseline to 0.037 +/- 0.014 MJ/kg after the diet (P < 0.001) and was higher after 52 wk (0.044 +/- 0.17 MJ/kg) compared with after 8 wk (P < 0.001). Activity counts decreased from 1.64 +/- 0.37 megacounts/d at baseline to 1.54 +/- 0.35 megacounts/d after the diet (P < 0.05) and were higher after 52 wk (1.73 +/- 0.49 megacounts/d) compared with 8 wk (P < 0.01). CONCLUSION: A weight loss-induced reduction in physical activity returns to baseline values when weight loss is maintained. This trial was registered at clinicaltrials.gov as NCT01015508.
- Published
- 2013