Search

Your search keyword '"Steeg, Patricia S."' showing total 808 results
Start Over Author "Steeg, Patricia S."
808 results on '"Steeg, Patricia S."'

2. National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities

Author

Kim, Michelle M, Mehta, Minesh P, Smart, DeeDee K, Steeg, Patricia S, Hong, Julie A, Espey, Michael G, Prasanna, Pataje G, Crandon, Laura, Hodgdon, Christine, Kozak, Niki, Armstrong, Terri S, Morikawa, Aki, Willmarth, Nicole, Tanner, Kirk, Boire, Adrienne, Gephart, Melanie Hayden, Margolin, Kim A, Hattangadi-Gluth, Jona, Tawbi, Hussein, Trifiletti, Daniel M, Chung, Caroline, Basu-Roy, Upal, Burns, Robyn, Oliva, Isabella C Glitza, Aizer, Ayal A, Anders, Carey K, Davis, Joanne, Ahluwalia, Manmeet S, Chiang, Veronica, Li, Jing, Kotecha, Rupesh, Formenti, Silvia C, Ellingson, Benjamin M, Gondi, Vinai, Sperduto, Paul W, Barnholtz-Sloan, Jill S, Rodon, Jordi, Lee, Eudocia Q, Khasraw, Mustafa, Yeboa, Debra Nana, Brastianos, Priscilla K, Galanis, Evanthia, Coleman, C Norman, and Ahmed, Mansoor M

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Brain Cancer, Rare Diseases, Clinical Research, Cancer, Brain Disorders, Good Health and Well Being, United States, Humans, Quality of Life, National Cancer Institute (U.S.), Biomedical Research, Consensus, Brain Neoplasms, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Brain metastases are an increasing global public health concern, even as survival rates improve for patients with metastatic disease. Both metastases and the sequelae of their treatment are key determinants of the inter-related priorities of patient survival, function, and quality of life, mandating a multidimensional approach to clinical care and research. At a virtual National Cancer Institute Workshop in September, 2022, key stakeholders convened to define research priorities to address the crucial areas of unmet need for patients with brain metastases to achieve meaningful advances in patient outcomes. This Policy Review outlines existing knowledge gaps, collaborative opportunities, and specific recommendations regarding consensus priorities and future directions in brain metastases research. Achieving major advances in research will require enhanced coordination between the ongoing efforts of individual organisations and consortia. Importantly, the continual and active engagement of patients and patient advocates will be necessary to ensure that the directionality of all efforts reflects what is most meaningful in the context of patient care.

Published
2023

5. Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

Author

Rodrigues, Gonçalo, Hoshino, Ayuko, Kenific, Candia M, Matei, Irina R, Steiner, Loïc, Freitas, Daniela, Kim, Han Sang, Oxley, Peter R, Scandariato, Ilana, Casanova-Salas, Irene, Dai, Jinxiang, Badwe, Chaitanya R, Gril, Brunilde, Tešić Mark, Milica, Dill, Brian D, Molina, Henrik, Zhang, Haiying, Benito-Martin, Alberto, Bojmar, Linda, Ararso, Yonathan, Offer, Katharine, LaPlant, Quincey, Buehring, Weston, Wang, Huajuan, Jiang, Xinran, Lu, Tyler M, Liu, Yuan, Sabari, Joshua K, Shin, Sandra J, Narula, Navneet, Ginter, Paula S, Rajasekhar, Vinagolu K, Healey, John H, Meylan, Etienne, Costa-Silva, Bruno, Wang, Shizhen Emily, Rafii, Shahin, Altorki, Nasser Khaled, Rudin, Charles M, Jones, David R, Steeg, Patricia S, Peinado, Héctor, Ghajar, Cyrus M, Bromberg, Jacqueline, de Sousa, Maria, Pisapia, David, and Lyden, David

Subjects
Biochemistry and Cell Biology, Biological Sciences, Cancer, Neurosciences, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Animals, Brain, Brain Neoplasms, Cell Line, Tumor, Cell Movement, Cell Proliferation, Chemokine CCL1, Chemokine CXCL1, Cyclooxygenase 2, Endothelial Cells, Exosomes, Gene Expression Regulation, Neoplastic, Humans, Hyaluronoglucosaminidase, Mice, Mice, Inbred C57BL, Mice, Nude, Neoplasm Metastasis, Neovascularization, Pathologic, Signal Transduction, Survival Analysis, Tumor Burden, Tumor Microenvironment, Tumor Necrosis Factor-alpha, Xenograft Model Antitumor Assays, Medical and Health Sciences, Developmental Biology, Biochemistry and cell biology
Abstract

The development of effective therapies against brain metastasis is currently hindered by limitations in our understanding of the molecular mechanisms driving it. Here we define the contributions of tumour-secreted exosomes to brain metastatic colonization and demonstrate that pre-conditioning the brain microenvironment with exosomes from brain metastatic cells enhances cancer cell outgrowth. Proteomic analysis identified cell migration-inducing and hyaluronan-binding protein (CEMIP) as elevated in exosomes from brain metastatic but not lung or bone metastatic cells. CEMIP depletion in tumour cells impaired brain metastasis, disrupting invasion and tumour cell association with the brain vasculature, phenotypes rescued by pre-conditioning the brain microenvironment with CEMIP+ exosomes. Moreover, uptake of CEMIP+ exosomes by brain endothelial and microglial cells induced endothelial cell branching and inflammation in the perivascular niche by upregulating the pro-inflammatory cytokines encoded by Ptgs2, Tnf and Ccl/Cxcl, known to promote brain vascular remodelling and metastasis. CEMIP was elevated in tumour tissues and exosomes from patients with brain metastasis and predicted brain metastasis progression and patient survival. Collectively, our findings suggest that targeting exosomal CEMIP could constitute a future avenue for the prevention and treatment of brain metastasis.

Published
2019

6. Brain metastases.

Author

Achrol, Achal Singh, Rennert, Robert C, Anders, Carey, Soffietti, Riccardo, Ahluwalia, Manmeet S, Nayak, Lakshmi, Peters, Solange, Arvold, Nils D, Harsh, Griffith R, Steeg, Patricia S, and Chang, Steven D

Subjects
Humans, Breast Neoplasms, Brain Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Antineoplastic Agents, Mass Screening, Prognosis, Immunotherapy, Drug Therapy, Radiotherapy, Quality of Life, Neuroimaging, Clinical Sciences
Abstract

An estimated 20% of all patients with cancer will develop brain metastases, with the majority of brain metastases occurring in those with lung, breast and colorectal cancers, melanoma or renal cell carcinoma. Brain metastases are thought to occur via seeding of circulating tumour cells into the brain microvasculature; within this unique microenvironment, tumour growth is promoted and the penetration of systemic medical therapies is limited. Development of brain metastases remains a substantial contributor to overall cancer mortality in patients with advanced-stage cancer because prognosis remains poor despite multimodal treatments and advances in systemic therapies, which include a combination of surgery, radiotherapy, chemotherapy, immunotherapy and targeted therapies. Thus, interest abounds in understanding the mechanisms that drive brain metastases so that they can be targeted with preventive therapeutic strategies and in understanding the molecular characteristics of brain metastases relative to the primary tumour so that they can inform targeted therapy selection. Increased molecular understanding of the disease will also drive continued development of novel immunotherapies and targeted therapies that have higher bioavailability beyond the blood-tumour barrier and drive advances in radiotherapies and minimally invasive surgical techniques. As these discoveries and innovations move from the realm of basic science to preclinical and clinical applications, future outcomes for patients with brain metastases are almost certain to improve.

Published
2019

8. Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer

Author

Silvestri, Vanesa L, primary, Tran, Andy D, additional, Chung, Monika, additional, Chung, Natalie, additional, Gril, Brunilde, additional, Robinson, Christina, additional, Difilippantonio, Simone, additional, Wei, Debbie, additional, Kruhlak, Michael J, additional, Peer, Cody J, additional, Figg, W Douglas, additional, Khan, Imran, additional, and Steeg, Patricia S, additional

Published
2024
Full Text
View/download PDF

12. Toward a Drug Development Path That Targets Metastatic Progression in Osteosarcoma

Author

Khanna, Chand, Fan, Timothy M, Gorlick, Richard, Helman, Lee J, Kleinerman, Eugenie S, Adamson, Peter C, Houghton, Peter J, Tap, William D, Welch, Danny R, Steeg, Patricia S, Merlino, Glenn, Sorensen, Poul HB, Meltzer, Paul, Kirsch, David G, Janeway, Katherine A, Weigel, Brenda, Randall, Lor, Withrow, Stephen J, Paoloni, Melissa, Kaplan, Rosandra, Teicher, Beverly A, Seibel, Nita L, Smith, Malcolm, Üren, Aykut, Patel, Shreyaskumar R, Trent, Jeffrey, Savage, Sharon A, Mirabello, Lisa, Reinke, Denise, Barkaukas, Donald A, Krailo, Mark, and Bernstein, Mark

Subjects
Pediatric Cancer, Pediatric Research Initiative, Pediatric, Orphan Drug, Rare Diseases, Cancer, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Good Health and Well Being, Animals, Antineoplastic Agents, Bone Neoplasms, Disease Models, Animal, Disease Progression, Dogs, Drug Evaluation, Preclinical, Humans, Osteosarcoma, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Despite successful primary tumor treatment, the development of pulmonary metastasis continues to be the most common cause of mortality in patients with osteosarcoma. A conventional drug development path requiring drugs to induce regression of established lesions has not led to improvements for patients with osteosarcoma in more than 30 years. On the basis of our growing understanding of metastasis biology, it is now reasonable and essential that we focus on developing therapeutics that target metastatic progression. To advance this agenda, a meeting of key opinion leaders and experts in the metastasis and osteosarcoma communities was convened in Bethesda, Maryland. The goal of this meeting was to provide a "Perspective" that would establish a preclinical translational path that could support the early evaluation of potential therapeutic agents that uniquely target the metastatic phenotype. Although focused on osteosarcoma, the need for this perspective is shared among many cancer types. The consensus achieved from the meeting included the following: the biology of metastatic progression is associated with metastasis-specific targets/processes that may not influence grossly detectable lesions; targeting of metastasis-specific processes is feasible; rigorous preclinical data are needed to support translation of metastasis-specific agents into human trials where regression of measurable disease is not an expected outcome; preclinical data should include an understanding of mechanism of action, validation of pharmacodynamic markers of effective exposure and response, the use of several murine models of effectiveness, and where feasible the inclusion of the dog with naturally occurring osteosarcoma to define the activity of new drugs in the micrometastatic disease setting.

Published
2014

14. Roadblocks to translational advances on metastasis research

Author

Brabletz, Thomas, Lyden, David, Steeg, Patricia S, and Werb, Zena

Subjects
Health Services and Systems, Biomedical and Clinical Sciences, Health Sciences, Cancer, Drug Discovery, Epithelial-Mesenchymal Transition, Humans, Neoplasm Metastasis, Neoplasms, Neoplastic Stem Cells, Translational Research, Biomedical, Translational Medical Research, Medical and Health Sciences, Immunology, Biomedical and clinical sciences, Health sciences
Abstract

Promising advances in cancer therapy stemming from an increasing understanding of the molecular and genetic underpinnings of the tumorigenic process have been fueled by a strong, determined scientific community, influential patient advocacy groups and committed funding bodies. Despite these efforts, the development of effective drugs to prevent systemic dissemination of cancer cells or to eliminate overt metastasis in secondary organs remains a challenge to both researchers and physicians. In an attempt to tackle the most relevant and timely translational issues, a meeting held in 2012 as a result of a successful partnership between the Volkswagen Foundation and Nature Medicine brought together a group of metastasis research experts to identify the most important hurdles and help create a framework for potential clinical and translational strategies.

Published
2013

16. A framework for the development of effective anti-metastatic agents

Author

Anderson, Robin L., Balasas, Theo, Callaghan, Juliana, Coombes, R. Charles, Evans, Jeff, Hall, Jacqueline A., Kinrade, Sally, Jones, David, Jones, Paul S., Jones, Rob, Marshall, John F., Panico, Maria Beatrice, Shaw, Jacqui A., Steeg, Patricia S., Sullivan, Mark, Tong, Warwick, Westwell, Andrew D., and Ritchie, James W. A.

Published
2019
Full Text
View/download PDF

17. Data from Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer

Author

Khan, Imran, primary, Gril, Brunilde, primary, Paranjape, Anurag N., primary, Robinson, Christina M., primary, Difilippantonio, Simone, primary, Biernat, Wojciech, primary, Bieńkowski, Michał, primary, Pęksa, Rafał, primary, Duchnowska, Renata, primary, Jassem, Jacek, primary, Brastianos, Priscilla K., primary, Metellus, Philippe, primary, Bialecki, Emilie, primary, Woodroofe, Carolyn C., primary, Wu, Haitao, primary, Swenson, Rolf E., primary, and Steeg, Patricia S., primary

Published
2023
Full Text
View/download PDF

18. Supplementary Figure S1-S10 from Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer

Author

Khan, Imran, primary, Gril, Brunilde, primary, Paranjape, Anurag N., primary, Robinson, Christina M., primary, Difilippantonio, Simone, primary, Biernat, Wojciech, primary, Bieńkowski, Michał, primary, Pęksa, Rafał, primary, Duchnowska, Renata, primary, Jassem, Jacek, primary, Brastianos, Priscilla K., primary, Metellus, Philippe, primary, Bialecki, Emilie, primary, Woodroofe, Carolyn C., primary, Wu, Haitao, primary, Swenson, Rolf E., primary, and Steeg, Patricia S., primary

Published
2023
Full Text
View/download PDF

19. Supplementary Table 1 from Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer

Author

Khan, Imran, primary, Gril, Brunilde, primary, Paranjape, Anurag N., primary, Robinson, Christina M., primary, Difilippantonio, Simone, primary, Biernat, Wojciech, primary, Bieńkowski, Michał, primary, Pęksa, Rafał, primary, Duchnowska, Renata, primary, Jassem, Jacek, primary, Brastianos, Priscilla K., primary, Metellus, Philippe, primary, Bialecki, Emilie, primary, Woodroofe, Carolyn C., primary, Wu, Haitao, primary, Swenson, Rolf E., primary, and Steeg, Patricia S., primary

Published
2023
Full Text
View/download PDF

20. Supplementary Material and Methods from Comparison of Three Transcytotic Pathways for Distribution to Brain Metastases of Breast Cancer

Author

Khan, Imran, primary, Gril, Brunilde, primary, Paranjape, Anurag N., primary, Robinson, Christina M., primary, Difilippantonio, Simone, primary, Biernat, Wojciech, primary, Bieńkowski, Michał, primary, Pęksa, Rafał, primary, Duchnowska, Renata, primary, Jassem, Jacek, primary, Brastianos, Priscilla K., primary, Metellus, Philippe, primary, Bialecki, Emilie, primary, Woodroofe, Carolyn C., primary, Wu, Haitao, primary, Swenson, Rolf E., primary, and Steeg, Patricia S., primary

Published
2023
Full Text
View/download PDF

21. Data from Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, primary, Steinberg, Seth M., primary, Nousome, Darryl, primary, Houston, Nicole, primary, Wu, Xiaolin, primary, Armstrong, Terri S., primary, Burton, Eric, primary, Smart, Dee Dee, primary, Shah, Ritu, primary, Peer, Cody J., primary, Mozarsky, Brett, primary, Arisa, Oluwatobi, primary, Figg, William D., primary, Mendoza, Tito R., primary, Vera, Elizabeth, primary, Brastianos, Priscilla, primary, Carter, Scott, primary, Gilbert, Mark R., primary, Anders, Carey K., primary, Connolly, Roisín M., primary, Tweed, Carol, primary, Smith, Karen L., primary, Khan, Imran, primary, Lipkowitz, Stanley, primary, Steeg, Patricia S., primary, and Zimmer, Alexandra S., primary

Published
2023
Full Text
View/download PDF

22. Supplementary Data 1 from Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, primary, Steinberg, Seth M., primary, Nousome, Darryl, primary, Houston, Nicole, primary, Wu, Xiaolin, primary, Armstrong, Terri S., primary, Burton, Eric, primary, Smart, Dee Dee, primary, Shah, Ritu, primary, Peer, Cody J., primary, Mozarsky, Brett, primary, Arisa, Oluwatobi, primary, Figg, William D., primary, Mendoza, Tito R., primary, Vera, Elizabeth, primary, Brastianos, Priscilla, primary, Carter, Scott, primary, Gilbert, Mark R., primary, Anders, Carey K., primary, Connolly, Roisín M., primary, Tweed, Carol, primary, Smith, Karen L., primary, Khan, Imran, primary, Lipkowitz, Stanley, primary, Steeg, Patricia S., primary, and Zimmer, Alexandra S., primary

Published
2023
Full Text
View/download PDF

23. Figure S1 from Phase I Study and Cell-Free DNA Analysis of T-DM1 and Metronomic Temozolomide for Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases

Author

Jenkins, Sarah, primary, Zhang, Wei, primary, Steinberg, Seth M., primary, Nousome, Darryl, primary, Houston, Nicole, primary, Wu, Xiaolin, primary, Armstrong, Terri S., primary, Burton, Eric, primary, Smart, Dee Dee, primary, Shah, Ritu, primary, Peer, Cody J., primary, Mozarsky, Brett, primary, Arisa, Oluwatobi, primary, Figg, William D., primary, Mendoza, Tito R., primary, Vera, Elizabeth, primary, Brastianos, Priscilla, primary, Carter, Scott, primary, Gilbert, Mark R., primary, Anders, Carey K., primary, Connolly, Roisín M., primary, Tweed, Carol, primary, Smith, Karen L., primary, Khan, Imran, primary, Lipkowitz, Stanley, primary, Steeg, Patricia S., primary, and Zimmer, Alexandra S., primary

Published
2023
Full Text
View/download PDF

25. Supplementary Table 1 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

26. Supplementary Figure 2 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

28. Data from Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model

Author

Mittapalli, Rajendar K., primary, Liu, Xinli, primary, Adkins, Chris E., primary, Nounou, Mohamed I., primary, Bohn, Kaci A., primary, Terrell, Tori B., primary, Qhattal, Hussaini S., primary, Geldenhuys, Werner J., primary, Palmieri, Diane, primary, Steeg, Patricia S., primary, Smith, Quentin R., primary, and Lockman, Paul R., primary

Published
2023
Full Text
View/download PDF

29. Supplementary Figure 6 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

31. Supplementary Figure 5 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

33. Supplementary Figures 1 through 3 from Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model

Author

Mittapalli, Rajendar K., primary, Liu, Xinli, primary, Adkins, Chris E., primary, Nounou, Mohamed I., primary, Bohn, Kaci A., primary, Terrell, Tori B., primary, Qhattal, Hussaini S., primary, Geldenhuys, Werner J., primary, Palmieri, Diane, primary, Steeg, Patricia S., primary, Smith, Quentin R., primary, and Lockman, Paul R., primary

Published
2023
Full Text
View/download PDF

35. Supplementary Figure 4 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

36. Data from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

37. Supplementary Figure 7 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

38. Supplementary Figure Legend from Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model

Author

Mittapalli, Rajendar K., primary, Liu, Xinli, primary, Adkins, Chris E., primary, Nounou, Mohamed I., primary, Bohn, Kaci A., primary, Terrell, Tori B., primary, Qhattal, Hussaini S., primary, Geldenhuys, Werner J., primary, Palmieri, Diane, primary, Steeg, Patricia S., primary, Smith, Quentin R., primary, and Lockman, Paul R., primary

Published
2023
Full Text
View/download PDF

39. Supplementary Figure 1 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

40. Supplementary Figure 3 from Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs

Author

Berghoff, Anna. S., primary, Liao, Yunxiang, primary, Karreman, Matthia A., primary, Ilhan-Mutlu, Ayseguel, primary, Gunkel, Katharina, primary, Sprick, Martin R., primary, Eisen, Christian, primary, Kessler, Tobias, primary, Osswald, Matthias, primary, Wünsche, Susanne, primary, Feinauer, Manuel, primary, Gril, Brunhilde, primary, Marmé, Frederic, primary, Michel, Laura L., primary, Bago-Horvath, Zuszanna, primary, Sahm, Felix, primary, Becker, Natalia, primary, Breckwoldt, Michael O., primary, Solecki, Gergely, primary, Gömmel, Miriam, primary, Huang, Lulu, primary, Rübmann, Petra, primary, Thome, Carina M., primary, Ratliff, Miriam, primary, Trumpp, Andreas, primary, Steeg, Patricia S., primary, Preusser, Matthias, primary, Wick, Wolfgang, primary, and Winkler, Frank, primary

Published
2023
Full Text
View/download PDF

44. Supplementary Figure Legends from Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner

Author

Palmieri, Diane, primary, Duchnowska, Renata, primary, Woditschka, Stephan, primary, Hua, Emily, primary, Qian, Yongzhen, primary, Biernat, Wojciech, primary, Sosińska-Mielcarek, Katarzyna, primary, Gril, Brunilde, primary, Stark, Andreas M., primary, Hewitt, Stephen M., primary, Liewehr, David J., primary, Steinberg, Seth M., primary, Jassem, Jacek, primary, and Steeg, Patricia S., primary

Published
2023
Full Text
View/download PDF

45. Supplementary Figure 1 from Profound Prevention of Experimental Brain Metastases of Breast Cancer by Temozolomide in an MGMT-Dependent Manner

Author

Palmieri, Diane, primary, Duchnowska, Renata, primary, Woditschka, Stephan, primary, Hua, Emily, primary, Qian, Yongzhen, primary, Biernat, Wojciech, primary, Sosińska-Mielcarek, Katarzyna, primary, Gril, Brunilde, primary, Stark, Andreas M., primary, Hewitt, Stephen M., primary, Liewehr, David J., primary, Steinberg, Seth M., primary, Jassem, Jacek, primary, and Steeg, Patricia S., primary

Published
2023
Full Text
View/download PDF

47. Supplementary Table S1 from Accelerated Preclinical Testing Using Transplanted Tumors from Genetically Engineered Mouse Breast Cancer Models

Author

Varticovski, Lyuba, primary, Hollingshead, Melinda G., primary, Robles, Ana I., primary, Wu, Xiaolin, primary, Cherry, James, primary, Munroe, David J., primary, Lukes, Luanne, primary, Anver, Miriam R., primary, Carter, John P., primary, Borgel, Suzanne D., primary, Stotler, Howard, primary, Bonomi, Carrie A., primary, Nunez, Nomelí P., primary, Hursting, Stephen D., primary, Qiao, Wenhui, primary, Deng, Chuxia X., primary, Green, Jeff E., primary, Hunter, Kent W., primary, Merlino, Glenn, primary, Steeg, Patricia S., primary, Wakefield, Lalage M., primary, and Barrett, J. Carl, primary

Published
2023
Full Text
View/download PDF

48. Supplementary Figures S1-S5 from Nelfinavir, A Lead HIV Protease Inhibitor, Is a Broad-Spectrum, Anticancer Agent that Induces Endoplasmic Reticulum Stress, Autophagy, and Apoptosis In vitro and In vivo

Author

Gills, Joell J., primary, LoPiccolo, Jaclyn, primary, Tsurutani, Junji, primary, Shoemaker, Robert H., primary, Best, Carolyn J.M., primary, Abu-Asab, Mones S., primary, Borojerdi, Jennifer, primary, Warfel, Noel A., primary, Gardner, Erin R., primary, Danish, Matthew, primary, Hollander, M. Christine, primary, Kawabata, Shigeru, primary, Tsokos, Maria, primary, Figg, William D., primary, Steeg, Patricia S., primary, and Dennis, Phillip A., primary

Published
2023
Full Text
View/download PDF

49. Supplementary Data File from Alterations in Pericyte Subpopulations Are Associated with Elevated Blood–Tumor Barrier Permeability in Experimental Brain Metastasis of Breast Cancer

Author

Lyle, L. Tiffany, primary, Lockman, Paul R., primary, Adkins, Chris E., primary, Mohammad, Afroz Shareef, primary, Sechrest, Emily, primary, Hua, Emily, primary, Palmieri, Diane, primary, Liewehr, David J., primary, Steinberg, Seth M., primary, Kloc, Wojciech, primary, Izycka-Swieszewska, Ewa, primary, Duchnowska, Renata, primary, Nayyar, Naema, primary, Brastianos, Priscilla K., primary, Steeg, Patricia S., primary, and Gril, Brunilde, primary

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results