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Your search keyword '"Starre-Gaal, Jose van der"' showing total 2 results
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2 results on '"Starre-Gaal, Jose van der"'

1. Formalin-free tissue embedding is less hazardous and results in better DNA quality.

Author

Niemantsverdriet, Maarten, Knol, Ageeth, Starre-Gaal, Jose van der, and Hoogland, Agnes Marije

Subjects
DNA, HAZARDOUS substances, FORMALDEHYDE, DIAGNOSIS, TISSUES
Abstract

Disease diagnosis, prognosis, and therapy choice progressively rely on good-quality Deoxyribonucleic acid (DNA) for molecular analysis. As tissue processing is routinely performed worldwide with ancient techniques using toxic and DNA-damaging formaldehyde, the quality of DNA isolated from embedded tissues used for diagnostics is poor. We used a novel formalin-free tissue embedding method to process tissues and show that, after 5 years, DNA quality is superior to formalin fixation. [ABSTRACT FROM AUTHOR]

Published
2024
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