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789 results on '"Stam, J."'

1. Quantitative analysis of phase formation and growth in ternary mixtures upon evaporation of one component

Author

Muntean, S. A., Kronberg, V. C. E., Colangeli, M., Muntean, A., van Stam, J., Moons, E., and Cirillo, E. N. M.

Subjects
Condensed Matter - Statistical Mechanics, 82M31
Abstract

We perform a quantitative analysis of Monte Carlo simulations results of phase separation in ternary blends upon evaporation of one component. Specifically, we calculate the average domain size and plot it as a function of simulation time to compute the exponent of the obtained power-law. We compare and discuss results obtained by two different methods, for three different models: 2D binary-state model (Ising model), 2D ternary-state model with and without evaporation. For the ternary-state models, we study additionally the dependence of the domain growth on concentration, temperature and initial composition. We reproduce the expected 1/3 exponent for the Ising model, while for the ternary-state model without evaporation and for the one with evaporation we obtain lower values of the exponent. It turns out that phase separation patterns that can form in this type of systems are complex. The obtained quantitative results give valuable insights towards devising computable theoretical estimations of size effects on morphologies as they occur in the context of organic solar cells., Comment: 9 pages

Published
2022
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2. Unravelling donor-acceptor film morphology formation for environmentally-friendly OPV ink formulations

Author

Holmes, NP, Munday, H, Barr, MG, Thomsen, L, Marcus, MA, Kilcoyne, ALD, Fahy, A, Van Stam, J, Dastoor, PC, and Moons, E

Subjects
Chemical Sciences, Organic Chemistry
Abstract

The challenge of coating organic photovoltaics (OPV) from green solvents is to achieve the required nanostructured interpenetrating network of donor and acceptor domains based on a rational choice of solvent approach as opposed to the usual trial-and-error methods. We demonstrate here that we can achieve a bicontinuous interpenetrating network with nanoscale phase separation for the chosen donor-acceptor material system poly[2,3-bis-(3-octyloxyphenyl)quinoxaline-5,8-diyl-alt-thiophene-2,5-diyl]:phenyl-C61 butyric acid methyl ester (TQ1:PC61BM) when processing from green solvent ink formulations. This structure is achieved by first calculating the Hansen solubility parameters (HSP) of the donor and acceptor materials, followed by careful choice of solvents with selective relative solubilities for the two materials based on the desired order of precipitation necessary for forming a nanostructured interdigitated network morphology. We found that the relative distances in Hansen space (Ra) between TQ1 and the primary solvent, on the one hand, and PC61BM and the primary solvent, on the other hand, could be correlated to the donor-acceptor morphology for the formulations based on the solvents d-limonene, anisole, and 2-methyl anisole, as well as the halogenated reference solvent o-dichlorobenzene. This nanostructured blend film morphology was characterised with scanning transmission X-ray microscopy (STXM) and transmission electron microscopy (TEM), and the film surface composition was analysed by near edge X-ray absorption fine structure (NEXAFS) spectroscopy. Hansen solubility theory, based on solution thermodynamics, has been used and we propose an HSP-based method that is a general platform for the rational design of ink formulations for solution-based organic electronics, in particular facilitating the green solvent transition of organic photovoltaics. Our results show that the bulk heterojunction morphology for a donor-acceptor system processed from customised solvent mixtures can be predicted by the HSP-based method with good reliability.

Published
2019

3. The association between viral load and concurrent human papillomavirus infection at the genital and anal sites of young women and the impact of vaccination

Author

Adema, D., Buist-Arkema, R., Beerens, A., Luijt, D., Meijer, S., Schirm, J., Peeters, M., Rossen, J., Verbakel, H., van Esch, P., Verweij, J., van der Eijk, A., Huisman, R., Kerkhof, C., Korff, H., Schutten, M., Velzing, J., Verduyn-Lunel, F., Lakbiach, S., van Rosmalen, P., Schuurman, R., Doorn, E., Masthoff, L., Pannekoek, E., Sigurdsson, V., Abma, D., Adams, K., Bruisten, S., Linde, I., Oostvogel, P., Touwen, C., Vermeulen, W., Brink, A., Nelissen, J., Wolffs, P., Duijvendijk, N., Schneeberger, P., Dinnissen van Poppel, M., Melchers, W., Poort, Y., Izore, M.Hooghiemstra, Huisman, H., Weel, J., Bosma, F., Geeraedts, F., Polman, I., Isala, P.van Goor, Wolfhagen, M., de Mooij, C., van Koolwijk, E., Peters, M., Swanink, C., Tiemessen, R., van Zwet, T., Janssen, J., Pelsers, M., de Waal, W., Aalfs, G., Kiewiet, J., Sanders, P., van Buel- Bruins, H., van Bokhoven-Rombouts, C., Cornelissen, P., Kersten, M., van Ruitenbeek, C., Molenaar, I., Bugter, M., Götz, H., Illidge-Onder de Linden, M., Mattijssen, M., Stam, J., Swaders, E., de Groot, F., Postma, F., Brouwers, E., Niekamp, A., Smit, M., Botraby, A., Bukasa, D., de Haan, C., Hut-van Vliet, P., Taconis, T., de Graas, M., Hondelink, I., Kampman, C., Gelissen-Hansen, A., de Koning, I., van Kruchten, H., van de Pas, M., Fennema, H., Heijman, T., Hogewoning, A., van Leeuwen, A., van Rooijen, M., Neienhuijsen, F., Pelgrim, M., van Eer, Kahren, Laâbi, Ihsane, van Benthem, Birgit H.B., Steenbergen, Renske D.M., and King, Audrey J.

Published
2022
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4. Engineering Two-Phase and Three-Phase Microstructures from Water-Based Dispersions of Nanoparticles for Eco-Friendly Polymer Solar Cell Applications

Author

Holmes, NP, Marks, M, Cave, JM, Feron, K, Barr, MG, Fahy, A, Sharma, A, Pan, X, Kilcoyne, DAL, Zhou, X, Lewis, DA, Andersson, MR, Van Stam, J, Walker, AB, Moons, E, Belcher, WJ, and Dastoor, PC

Subjects
Chemical Sciences, Engineering, Materials
Abstract

Nanoparticle organic photovoltaics, a subfield of organic photovoltaics (OPV), has attracted increasing interest in recent years due to the eco-friendly fabrication of solar modules afforded by colloidal ink technology. Importantly, using this approach it is now possible to engineer the microstructure of the light absorbing/charge generating layer of organic photovoltaics; decoupling film morphology from film deposition. In this study, single-component nanoparticles of poly(3-hexylthiophene) (P3HT) and phenyl-C61 butyric acid methyl ester (PC61BM) were synthesized and used to generate a two-phase microstructure with control over domain size prior to film deposition. Scanning transmission X-ray microscopy (STXM) and electron microscopy were used to characterize the thin film morphology. Uniquely, the measured microstructure was a direct input for a nanoscopic kinetic Monte Carlo (KMC) model allowing us to assess exciton transport properties that are experimentally inaccessible in these single-component particles. Photoluminescence, UV-vis spectroscopy measurements, and KMC results of the nanoparticle thin films enabled the calculation of an experimental exciton dissociation efficiency (ηED) of 37% for the two-phase microstructure. The glass transition temperature (Tg) of the materials was characterized with dynamic mechanical thermal analysis (DMTA) and thermal annealing led to an increase in ηED to 64% due to an increase in donor-acceptor interfaces in the thin film from both sintering of neighboring opposite-type particles in addition to the generation of a third mixed phase from diffusion of PC61BM into amorphous P3HT domains. As such, this study demonstrates the higher level of control over donor-acceptor film morphology enabled by customizing nanoparticulate colloidal inks, where the optimal three-phase film morphology for an OPV photoactive layer can be designed and engineered.

Published
2018

5. Behavior of the reflection function of a plane-parallel medium for directions of incidence and reflection tending to horizontal directions

Author

Stam, J. W. Hovenier D. M.

Subjects
Astrophysics
Abstract

The atmospheres of (exo) planets and moons, as well as reflection nebulae, contain in general independently scattering particles in random orientation and are often supposed to be plane-parallel. Relations are presented for the (bidirectional) reflection function and several related functions of such a medium in case the directions of incidence and reflection both tend to horizontal directions. The results are quite general. The medium may be semi-infinite or finite, with or without a reflecting surface underneath, and vertically homogeneous or inhomogeneous. Some approximative formulae for the reflection function of a plane-parallel medium with independently scattering particles in random orientation, including Lambert's law, may be very inaccurate if the directions of incidence and reflection are both nearly horizontal., Comment: Accepted for publication in Astron. Astrophys

Published
2008

6. No evidence for cross-protection of the HPV-16/18 vaccine against HPV-6/11 positivity in female STI clinic visitors

Author

Adema, D., Buist-Arkema, R., Beerens, A., Luijt, D., Meijer, S., Schirm, J., Buiting, A., Peeters, M., Rossen, J., Verbakel, H., van Esch, P., Verweij, J., van der Eijk, A., Huisman, R., Kerkhof, C., Korff, H., Schutten, M., Velzing, J., Verduyn-Lunel, F., Lakbiach, S., van Rosmalen, P., Schuurman, R., Abma, D., Adams, K., Bruisten, S., Linde, I., Oostvogel, P., Touwen, C., Vermeulen, W., Brink, A., Nelissen, J., Wolffs, P., Duijvendijk, N., Schneeberger, P., Dinnissen-van Poppel, M., Melchers, W., Poort, Y., Hooghiemstra, M., Huisman, H., Weel, J., Bosch, H., de Haas, T., Kleinspenkelink, R., Polman, I., Smits, T., van Goor, P., Wolfhagen, M., de Mooij, C., van Koolwijk, E., Peters, M., Swanink, C., Tiemessen, R., van Zwet, T., Janssen, J., Pelsers, M., de Waal, W., Aalfs, G., Kiewiet, J., Sanders, P., van Buel-Bruins, H., van Bokhoven-Rombouts, C., Cornelissen, P., Kersten, M., van Ruitenbeek, C., Molenaar, I., Doorn, E., Masthoff, L., Pannekoek, E., Sigurdsson, V., Götz, H., Illidge-Onder de Linden, M., Mattijssen, M., Stam, J., Swaders, E., de Groot, F., Postma, F., Brouwers, E., Niekamp, A., Smit, M., Botraby, A., Bukasa, D., de Haan, C., Hut-van Vliet, P., Taconis, T., de Graas, M., Hondelink, I., Kampman, C., Gelissen-Hansen, A., de Koning, I., van Kruchten, H., van de Pas, M., Fennema, H., Heijman, T., Hogewoning, A., van Leeuwen, A., van Rooijen, M., Neienhuijsen, F., Pelgrim, M., Woestenberg, Petra J., King, Audrey J., van der Sande, Marianne A.B., Donken, Robine, Leussink, Suzan, van der Klis, Fiona R.M., Hoebe, Christian J.P.A., Bogaards, Johannes A., and van Benthem, Birgit H.B.

Published
2017
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9. Prodromal Transient Ischemic Attack or Minor Stroke and Outcome in Basilar Artery Occlusion

Author

Weber, A.M., Donnan, G.A., Thijs, V., Peeters, A., de Freitas, G.R., Conforto, A.B., Miranda-Alves, M., Massaro, A., Ijäs, P., Bogoslovsky, T., Lindsberg, P.J., Weimar, C., Benemann, J., Kraywinkel, K., Haverkamp, C., Michalski, D., Weissenborn, K., Goertler, M., Kloth, A., Bitsch, A., Mieck, T., Machetanz, J., Möller, P., Huber, R., Kaendler, S., Rueckert, C., Audebert, H., Müller, R., Vatankhah, B., Pfefferkorn, T., Mayer, T.E., Szabo, K., Disque, C., Busse, O., Berger, C., Hacke, W., Schwammenthal, Y., Orion, D., Tanne, D., Bergui, M., Pozzati, E., Schonewille, W.J., Algra, A., Kappelle, L.J., Luijckx, G.J., Vroomen, P., Vergouwen, M.D., Roos, Y., Stam, J., Bienfait, P., de Leeuw, F.E., de Kort, P., Dippel, D., Baird, T., Muir, K., Pagola, J., Ribo, M., Molina, C., Gonzales, A., Gil-Peralta, A., Norrving, B., Arnold, M., Fischer, U., Gralla, J., Mattle, H., Schroth, G., Michel, P., Engelter, S.T., Wetzel, S., Lyrer, P., Gandjour, J., Michael, N., Baumgartner, R., Tettenborn, B., Hungerbuehler, H., Wijman, C.A.C., Finley Caulfield, A., Lansberg, M., Schwartz, N., Venkatasubramanian, C., Garami, Z., Bogaard, S., Yatzu, F., Grotta, J., Conforto, Adriana B., de Freitas, Gabriel R., Schonewille, Wouter J., Kappelle, L. Jaap, and Algra, Ale

Published
2015
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10. Artikel 71. Parlementaire immuniteit

Author

Ellian, Afshin, Stam, J., Rijpkema, Bastiaan, RS-Research Program Transformative effects of Globalisation and Law (TGL), RS-Research Program Law in a network society (LNS), and Department of Public Law

Published
2022

13. Role of Tiam 1 in Rac-Mediated Signal Transduction Pathways

Author

Collard, J. G., Habets, G. G. M., Michiels, F., Stam, J., van der Kammen, R. A., van Leeuwen, F., Compans, R. W., editor, Cooper, M., editor, Koprowski, H., editor, Melchers, F., editor, Oldstone, M., editor, Olsnes, S., editor, Potter, M., editor, Saedler, H., editor, Vogt, P. K., editor, Wagner, H., editor, Günthert, Ursula, editor, and Birchmeier, Walter, editor

Published
1996
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14. Wilders II: Het onverdraagzaamheidscriterium toegepast door de Hoge Raad

Author

Molier, G., Rijpkema, B.R., and Stam, J.

Abstract

Met het Wilders II-arrest heeft de Hoge Raad een verdere invulling gegeven aan het in het Felter-arrest geïntroduceerde onverdraagzaamheidscriterium. Helder is nu dat dit criterium geactiveerd wordt wanneer er sprake is van beledigende uitlatingen specifiek gericht tegen een minderheidsgroep. Dergelijke uitlatingen, in de specifieke wijze waarop deze gedaan werden in Wilders II, dienen binnen het toetsingskader van artikel 137c (en d) Sr als ‘onnodig grievend’ te worden beoordeeld. Een politicus verliest daarmee de bescherming die de disculperende context van het maatschappelijke debat hem of haar normaal gesproken kan bieden. In diezelfde beweging heeft de Hoge Raad de artikelen 137c en 137d Sr nu nog duidelijker in de sfeer van de weerbare democratie getrokken, dat wil zeggen: als bepalingen (mede) ter verdediging van de democratische rechtsstaat.

Published
2021

18. The association between viral load and concurrent human papillomavirus infection at the genital and anal sites of young women and the impact of vaccination

Author

van Eer, Kahren, primary, Laâbi, Ihsane, additional, van Benthem, Birgit H.B., additional, Steenbergen, Renske D.M., additional, King, Audrey J., additional, Adema, D., additional, Buist-Arkema, R., additional, Beerens, A., additional, Luijt, D., additional, Meijer, S., additional, Schirm, J., additional, Peeters, M., additional, Rossen, J., additional, Verbakel, H., additional, van Esch, P., additional, Verweij, J., additional, van der Eijk, A., additional, Huisman, R., additional, Kerkhof, C., additional, Korff, H., additional, Schutten, M., additional, Velzing, J., additional, Verduyn-Lunel, F., additional, Lakbiach, S., additional, van Rosmalen, P., additional, Schuurman, R., additional, Doorn, E., additional, Masthoff, L., additional, Pannekoek, E., additional, Sigurdsson, V., additional, Abma, D., additional, Adams, K., additional, Bruisten, S., additional, Linde, I., additional, Oostvogel, P., additional, Touwen, C., additional, Vermeulen, W., additional, Brink, A., additional, Nelissen, J., additional, Wolffs, P., additional, Duijvendijk, N., additional, Schneeberger, P., additional, Dinnissen van Poppel, M., additional, Melchers, W., additional, Poort, Y., additional, Hooghiemstra, Izore: M., additional, Huisman, H., additional, Weel, J., additional, Bosma, F., additional, Geeraedts, F., additional, Polman, I., additional, van Goor, Isala: P., additional, Wolfhagen. Rijnstate, M., additional, de Mooij, C., additional, van Koolwijk, E., additional, Peters, M., additional, Swanink, C., additional, Tiemessen, R., additional, van Zwet, T., additional, Janssen, J., additional, Pelsers, M., additional, de Waal, W., additional, Aalfs, G., additional, Kiewiet, J., additional, Sanders, P., additional, van Buel- Bruins, H., additional, van Bokhoven-Rombouts, C., additional, Cornelissen, P., additional, Kersten, M., additional, van Ruitenbeek, C., additional, Molenaar, I., additional, Bugter, M., additional, Götz, H., additional, Illidge-Onder de Linden, M., additional, Mattijssen, M., additional, Stam, J., additional, Swaders, E., additional, de Groot, F., additional, Postma, F., additional, Brouwers, E., additional, Niekamp, A., additional, Smit, M., additional, Botraby, A., additional, Bukasa, D., additional, de Haan, C., additional, Hut-van Vliet, P., additional, Taconis, T., additional, de Graas, M., additional, Hondelink, I., additional, Kampman, C., additional, Gelissen-Hansen, A., additional, de Koning, I., additional, van Kruchten, H., additional, van de Pas, M., additional, Fennema, H., additional, Heijman, T., additional, Hogewoning, A., additional, van Leeuwen, A., additional, van Rooijen, M., additional, Neienhuijsen, F., additional, and Pelgrim, M., additional

Published
2021
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21. Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Author

Best J.G., Ambler G., Wilson D., Lee K.-J., Lim J.-S., Shiozawa M., Koga M., Li L., Lovelock C., Chabriat H., Hennerici M., Wong Y.K., Mak H.K.F., Prats-Sanchez L., Martinez-Domeno A., Inamura S., Yoshifuji K., Arsava E.M., Horstmann S., Purrucker J., Lam B.Y.K., Wong A., Kim Y.D., Song T.-J., Lemmens R., Eppinger S., Gattringer T., Uysal E., Tanriverdi Z., Bornstein N.M., Ben Assayag E., Hallevi H., Molad J., Nishihara M., Tanaka J., Coutts S.B., Polymeris A., Wagner B., Seiffge D.J., Lyrer P., Algra A., Kappelle L.J., Al-Shahi Salman R., Jager H.R., Lip G.Y.H., Fischer U., El-Koussy M., Mas J.-L., Legrand L., Karayiannis C., Phan T., Gunkel S., Christ N., Abrigo J., Leung T., Chu W., Chappell F., Makin S., Hayden D., Williams D.J., Mess W.H., Nederkoorn P.J., Barbato C., Browning S., Wiegertjes K., Tuladhar A.M., Maaijwee N., Guevarra A.C., Yatawara C., Mendyk A.-M., Delmaire C., Kohler S., van Oostenbrugge R., Zhou Y., Xu C., Hilal S., Gyanwali B., Chen C., Lou M., Staals J., Bordet R., Kandiah N., de Leeuw F.-E., Simister R., Hendrikse J., Kelly P.J., Wardlaw J., Soo Y., Fluri F., Srikanth V., Calvet D., Jung S., Kwa V.I.H., Engelter S.T., Peters N., Smith E.E., Hara H., Yakushiji Y., Orken D.N., Fazekas F., Thijs V., Heo J.H., Mok V., Veltkamp R., Ay H., Imaizumi T., Gomez-Anson B., Lau K.K., Jouvent E., Rothwell P.M., Toyoda K., Bae H.-J., Marti-Fabregas J., Werring D.J., Harkness K., Shaw L., Sword J., Mohd Nor A., Sharma P., Kelly D., Harrington F., Randall M., Smith M., Mahawish K., Elmarim A., Esisi B., Cullen C., Nallasivam A., Price C., Barry A., Roffe C., Coyle J., Hassan A., Birns J., Cohen D., Sekaran L., Parry-Jones A., Parry A., Hargroves D., Proschel H., Datta P., Darawil K., Manoj A., Burn M., Patterson C., Giallombardo E., Smyth N., Mansoor S., Anwar I., Marsh R., Ispoglou S., Chadha D., Prabhakaran M., Meenakishundaram S., O'Connell J., Scott J., Krishnamurthy V., Aghoram P., McCormick M., Sprigg N., O'Mahony P., Cooper M., Choy L., Wilkinson P., Leach S., Caine S., Burger I., Gunathilagan G., Guyler P., Emsley H., Davis M., Manawadu D., Pasco K., Mamun M., Luder R., Sajid M., Okwera J., Warburton E., Saastamoinen K., England T., Putterill J., Flossman E., Power M., Dani K., Mangion D., Suman A., Corrigan J., Lawrence E., Vahidassr D., Shakeshaft C., Brown M., Charidimou A., Cohen H., Banerjee G., Houlden H., White M., Yousry T., Flossmann E., Muir K., Gratz P., Mattle H., Panos L., Korczyn A., Kliper E., Maeder P., Gass A., Pachai C., Bracoub L., Douste-Blazy M.-Y., Fratacci M.D., Vicaut E., Sato S., Miwa K., Fujita K., Ide T., Ma H., Ly J., Singhal S., Chandra R., Slater L.-A., Soufan C., Moran C., Traenka C., Thilemann S., Fladt J., Gensicke H., Bonati L., Kim B.J., Han M.-K., Kang J., Ko E., Yang M.H., Jang M.S., Murphy S., Carty F., Akijian L., Thornton J., Schembri M., Douven E., Delgado-Mederos R., Marin R., Camps-Renom P., Guisado-Alonso D., Nunez F., Medrano-Martorell S., Merino E., Iida K., Ikeda S., Irie H., Demirelli D.S., Medanta J.M., Zerna C., Hernandez M.V., Armitage P., Heye A., Munoz-Maniega S., Sakka E., Thrippleton M., Dennis M., Beigneux Y., Silva M., Venketasubramanian N., Ho S.L., Cheung R.T.F., Chan K.H., Teo K.C., Hui E., Kwan J.S.K., Chang R., Tse M.Y., Hoi C.P., Chan C.Y., Chan O.L., Cheung R.H.K., Wong E.K.M., Leung K.T., Tsang S.F., Ip H.L., Ma S.H., Ma K., Fong W.C., Li S.H., Li R., Ng P.W., Wong K.K., Liu W., Wong L., Ramos L., De Schryver E., Jobsis J., van der Sande J., Brouwers P., Roos Y., Stam J., Bakker S., Verbiest H., Schoonewille W., Linn C., Hertzberger L., van Gemert M., Berntsen P., Van Dam-Nolen D., Kooi M.E., Van der Lugt A., Koudstaal P., Leff A., Ward N., Nachev P., Perry R., Ozkan H., Mitchell J., Best J.G., Ambler G., Wilson D., Lee K.-J., Lim J.-S., Shiozawa M., Koga M., Li L., Lovelock C., Chabriat H., Hennerici M., Wong Y.K., Mak H.K.F., Prats-Sanchez L., Martinez-Domeno A., Inamura S., Yoshifuji K., Arsava E.M., Horstmann S., Purrucker J., Lam B.Y.K., Wong A., Kim Y.D., Song T.-J., Lemmens R., Eppinger S., Gattringer T., Uysal E., Tanriverdi Z., Bornstein N.M., Ben Assayag E., Hallevi H., Molad J., Nishihara M., Tanaka J., Coutts S.B., Polymeris A., Wagner B., Seiffge D.J., Lyrer P., Algra A., Kappelle L.J., Al-Shahi Salman R., Jager H.R., Lip G.Y.H., Fischer U., El-Koussy M., Mas J.-L., Legrand L., Karayiannis C., Phan T., Gunkel S., Christ N., Abrigo J., Leung T., Chu W., Chappell F., Makin S., Hayden D., Williams D.J., Mess W.H., Nederkoorn P.J., Barbato C., Browning S., Wiegertjes K., Tuladhar A.M., Maaijwee N., Guevarra A.C., Yatawara C., Mendyk A.-M., Delmaire C., Kohler S., van Oostenbrugge R., Zhou Y., Xu C., Hilal S., Gyanwali B., Chen C., Lou M., Staals J., Bordet R., Kandiah N., de Leeuw F.-E., Simister R., Hendrikse J., Kelly P.J., Wardlaw J., Soo Y., Fluri F., Srikanth V., Calvet D., Jung S., Kwa V.I.H., Engelter S.T., Peters N., Smith E.E., Hara H., Yakushiji Y., Orken D.N., Fazekas F., Thijs V., Heo J.H., Mok V., Veltkamp R., Ay H., Imaizumi T., Gomez-Anson B., Lau K.K., Jouvent E., Rothwell P.M., Toyoda K., Bae H.-J., Marti-Fabregas J., Werring D.J., Harkness K., Shaw L., Sword J., Mohd Nor A., Sharma P., Kelly D., Harrington F., Randall M., Smith M., Mahawish K., Elmarim A., Esisi B., Cullen C., Nallasivam A., Price C., Barry A., Roffe C., Coyle J., Hassan A., Birns J., Cohen D., Sekaran L., Parry-Jones A., Parry A., Hargroves D., Proschel H., Datta P., Darawil K., Manoj A., Burn M., Patterson C., Giallombardo E., Smyth N., Mansoor S., Anwar I., Marsh R., Ispoglou S., Chadha D., Prabhakaran M., Meenakishundaram S., O'Connell J., Scott J., Krishnamurthy V., Aghoram P., McCormick M., Sprigg N., O'Mahony P., Cooper M., Choy L., Wilkinson P., Leach S., Caine S., Burger I., Gunathilagan G., Guyler P., Emsley H., Davis M., Manawadu D., Pasco K., Mamun M., Luder R., Sajid M., Okwera J., Warburton E., Saastamoinen K., England T., Putterill J., Flossman E., Power M., Dani K., Mangion D., Suman A., Corrigan J., Lawrence E., Vahidassr D., Shakeshaft C., Brown M., Charidimou A., Cohen H., Banerjee G., Houlden H., White M., Yousry T., Flossmann E., Muir K., Gratz P., Mattle H., Panos L., Korczyn A., Kliper E., Maeder P., Gass A., Pachai C., Bracoub L., Douste-Blazy M.-Y., Fratacci M.D., Vicaut E., Sato S., Miwa K., Fujita K., Ide T., Ma H., Ly J., Singhal S., Chandra R., Slater L.-A., Soufan C., Moran C., Traenka C., Thilemann S., Fladt J., Gensicke H., Bonati L., Kim B.J., Han M.-K., Kang J., Ko E., Yang M.H., Jang M.S., Murphy S., Carty F., Akijian L., Thornton J., Schembri M., Douven E., Delgado-Mederos R., Marin R., Camps-Renom P., Guisado-Alonso D., Nunez F., Medrano-Martorell S., Merino E., Iida K., Ikeda S., Irie H., Demirelli D.S., Medanta J.M., Zerna C., Hernandez M.V., Armitage P., Heye A., Munoz-Maniega S., Sakka E., Thrippleton M., Dennis M., Beigneux Y., Silva M., Venketasubramanian N., Ho S.L., Cheung R.T.F., Chan K.H., Teo K.C., Hui E., Kwan J.S.K., Chang R., Tse M.Y., Hoi C.P., Chan C.Y., Chan O.L., Cheung R.H.K., Wong E.K.M., Leung K.T., Tsang S.F., Ip H.L., Ma S.H., Ma K., Fong W.C., Li S.H., Li R., Ng P.W., Wong K.K., Liu W., Wong L., Ramos L., De Schryver E., Jobsis J., van der Sande J., Brouwers P., Roos Y., Stam J., Bakker S., Verbiest H., Schoonewille W., Linn C., Hertzberger L., van Gemert M., Berntsen P., Van Dam-Nolen D., Kooi M.E., Van der Lugt A., Koudstaal P., Leff A., Ward N., Nachev P., Perry R., Ozkan H., and Mitchell J.

Abstract

Background: Balancing the risks of recurrent ischaemic stroke and intracranial haemorrhage is important for patients treated with antithrombotic therapy after ischaemic stroke or transient ischaemic attack. However, existing predictive models offer insufficient performance, particularly for assessing the risk of intracranial haemorrhage. We aimed to develop new risk scores incorporating clinical variables and cerebral microbleeds, an MRI biomarker of intracranial haemorrhage and ischaemic stroke risk. Method(s): We did a pooled analysis of individual-patient data from the Microbleeds International Collaborative Network (MICON), which includes 38 hospital-based prospective cohort studies from 18 countries. All studies recruited participants with previous ischaemic stroke or transient ischaemic attack, acquired baseline MRI allowing quantification of cerebral microbleeds, and followed-up participants for ischaemic stroke and intracranial haemorrhage. Participants not taking antithrombotic drugs were excluded. We developed Cox regression models to predict the 5-year risks of intracranial haemorrhage and ischaemic stroke, selecting candidate predictors on biological relevance and simplifying models using backward elimination. We derived integer risk scores for clinical use. We assessed model performance in internal validation, adjusted for optimism using bootstrapping. The study is registered on PROSPERO, CRD42016036602. Finding(s): The included studies recruited participants between Aug 28, 2001, and Feb 4, 2018. 15 766 participants had follow-up for intracranial haemorrhage, and 15 784 for ischaemic stroke. Over a median follow-up of 2 years, 184 intracranial haemorrhages and 1048 ischaemic strokes were reported. The risk models we developed included cerebral microbleed burden and simple clinical variables. Optimism-adjusted c indices were 0.73 (95% CI 0.69-0.77) with a calibration slope of 0.94 (0.81-1.06) for the intracranial haemorrhage model and 0.63 (0.62-0.65) w

Published
2021

22. Population Impact of Girls-Only Human Papillomavirus 16/18 Vaccination in the Netherlands: Cross-Protective and Second-Order Herd Effects

Author

Cardiometabolic Health, Global Health, JC onderzoeksprogramma Cardiovascular Health, MMB Medische Staf, Infection & Immunity, MMB Staf diagnostiek, Hoes, Joske, Woestenberg, Petra J., Bogaards, Johannes A., King, Audrey J., De Melker, Hester E., Berkhof, Johannes, Hoebe, Christian J.P.A., Van Der Sande, Marianne A.B., Van Benthem, Birgit H.B., Adema, D., Buist-Arkema, R., Luijt, D., Meijer, S., Schirm, J., Buiting, A., Verbakel, H., Van Esch, P., Verweij, J., Van Der Eijk, A., Verduyn Lunel, F., Lakbiach, S., Schuurman, R., Abma, D., Adams, K., Bruisten, S., Linde, I., Oostvogel, P., Touwen, C., Vermeulen, W., Nelissen, J., Wolffs, P., Van Duijvendijk, N., Schneeberger, P., Dinnissen-Van Poppel, M., Melchers, W., Hooghiemstra, M., Huisman, H., Weel, J., Bosma, F., Geeraedts, F., Polman, I., Van Goor, P., Wolfhagen, M., Van Koolwijk, E., Peters, M., Swanink, C., Tiemessen, R., Janssen, J., Pelsers, M., De Waal, W., Aalfs, G., Van Buel, H., Van Bokhoven-Rombouts, C., Cornelissen, P., Kersten, M., Van Ruitenbeek, C., Molenaar, I., Doorn, E., Götz, H., Illidge, M., Stam, J., Swaders, E., Postma, F., Niekamp, A. M., Smit, M., Bukasa, D., Chirandjilal, M., Taconis, T., De Graas, M., Hondelink, I., Kampman, C., Van De Pas, M., Heijman, T., Hogewoning, A., Van Rooijen, M., Neienhuijsen, F., Pelgrim, M., Cardiometabolic Health, Global Health, JC onderzoeksprogramma Cardiovascular Health, MMB Medische Staf, Infection & Immunity, MMB Staf diagnostiek, Hoes, Joske, Woestenberg, Petra J., Bogaards, Johannes A., King, Audrey J., De Melker, Hester E., Berkhof, Johannes, Hoebe, Christian J.P.A., Van Der Sande, Marianne A.B., Van Benthem, Birgit H.B., Adema, D., Buist-Arkema, R., Luijt, D., Meijer, S., Schirm, J., Buiting, A., Verbakel, H., Van Esch, P., Verweij, J., Van Der Eijk, A., Verduyn Lunel, F., Lakbiach, S., Schuurman, R., Abma, D., Adams, K., Bruisten, S., Linde, I., Oostvogel, P., Touwen, C., Vermeulen, W., Nelissen, J., Wolffs, P., Van Duijvendijk, N., Schneeberger, P., Dinnissen-Van Poppel, M., Melchers, W., Hooghiemstra, M., Huisman, H., Weel, J., Bosma, F., Geeraedts, F., Polman, I., Van Goor, P., Wolfhagen, M., Van Koolwijk, E., Peters, M., Swanink, C., Tiemessen, R., Janssen, J., Pelsers, M., De Waal, W., Aalfs, G., Van Buel, H., Van Bokhoven-Rombouts, C., Cornelissen, P., Kersten, M., Van Ruitenbeek, C., Molenaar, I., Doorn, E., Götz, H., Illidge, M., Stam, J., Swaders, E., Postma, F., Niekamp, A. M., Smit, M., Bukasa, D., Chirandjilal, M., Taconis, T., De Graas, M., Hondelink, I., Kampman, C., Van De Pas, M., Heijman, T., Hogewoning, A., Van Rooijen, M., Neienhuijsen, F., and Pelgrim, M.

Published
2021

27. Potential of COmbined drive of Fuel cell And Internal Combustion Engine (COFAICE) for naval ships

Author

Sapra, H, Stam, J, van Biert, L, de Vos, P, Visser, K, and Meijn, G

Subjects
COFAICE, System integration, Solid oxide fuel cell, Optimal load, Marine natural gas engine, Naval ships
Abstract

Naval vessels around the world are looking to reduce their fuel consumption to not only drive down their environmental impact, but also gain the additional benefit of improving their endurance and reducing their (strategic) dependency on their primary fuel sources. Therefore, based on the strategic value of fuel in the operational environment, multiple navies around the world are investigating alternative energy conversion devices and fuels. In recent years, solid oxide fuel cells (SOFCs) have gathered increasing attention for maritime applications as an alternative to the traditional diesel engines. SOFCs showcase high power generation efficiency, ultralow emissions and noise-free operation, which are ideal pre-requisites for power generation onboard naval and commercial ships. Capitalizing on these attributes of SOFCs, this paper aims to investigate the potential of a novel COmbined drive of Fuel cell And Internal Combustion Engine (COFAICE) for naval vessels that employs a SOFC-ICE integration concept for power generation. In this paper, the performance of SOFC-ICE integration is tested for three different case studies of naval ships, namely, an oceangoing patrol vessel, a landing platform dock and a high-speed surface combatant. We investigate the optimal load sharing between the two energy conversion devices for different operational profiles and operating modes of a notional naval vessel. Optimal load sharing strategies are generated to study the impact on power-generation efficiency and CO2 emissions while taking into account the space and weight considerations for the system and fuel bunkering. The performance of the natural gas-fuelled SOFC-ICE integration concept is compared against the conventional and existing power plants onboard comparable ships. Furthermore, based on the optimal power split, potential of two SOFC-ICE integration methods are investigated for part-load operations. We find that significant improvements in efficiency and CO2 emission reductions can be achieved for the integrated SOFC-ICE power plants with optimized space and weight considerations.

Published
2020

34. Cerebral Venous and Sinus Thrombosis

Author

Einhäupl, K., primary, Stam, J., additional, Bousser, M.-G., additional, de Bruijn, S. F. T. M., additional, Ferro, J. M., additional, Martinelli, I., additional, and Masuhr, F., additional

Published
2010
Full Text
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44. Multifunctional river Groynes

Author

Abe, Shuya, primary, Yasuharu Watanabe, Dr, additional, Bauer, Christian, additional, Röttcher, Klaus, additional, Tönsmann, Frank, additional, Bettmann, T, additional, Webler, H, additional, Nijland, H, additional, Eerden, H, additional, Betts, H, additional, Joy, C, additional, Haslam, W, additional, Hallam, A, additional, Xingping, Jin, additional, Bose, Shivashish, additional, Ahmed Choudhury, Giasuddin, additional, Couderé, K, additional, Gommers, A, additional, Dauwe, W, additional, Flikweert, J, additional, Blommaar, P, additional, van Gerven, K, additional, Akkerman, G, additional, Akkerman, P, additional, Gudkov, D, additional, Derevets, V, additional, Kireev, S, additional, Nazarov, A, additional, Harries, T, additional, Tapsell, S, additional, Havinga, H, additional, Roovers, G, additional, Stamm, J, additional, Fischenich, C, additional, Khan, A, additional, Kreibich, H, additional, Thieken, A, additional, Merz, B, additional, Müller, M, additional, Li, Kungang, additional, van Linn, A, additional, Köngeter, J, additional, Majewski, W, additional, Jasinska, E, additional, Masumoto, T, additional, Hai, Pham, additional, Shimizu, K, additional, Niemeyer, M, additional, Schaap, G, additional, Ogunyoye, F, additional, Bray, R, additional, Gunasekara, R, additional, Vigor, M, additional, Pichel, G, additional, Jost, C, additional, Rouas, G, additional, van Schijndel, S, additional, Jagers, H, additional, Mosselman, E, additional, Schropp, M, additional, Savin, A, additional, Stere, C, additional, Kersting, N, additional, Waals*, J, additional, Kool, H, additional, Van Zutven, B, additional, van der Wal, M, additional, and Stam, J, additional

Published
2006
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