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462 results on '"Stalenhoef, Anton F. H."'

1. Cardiometabolic Differences in People Living with HIV Receiving Integrase Strand Transfer Inhibitors Compared to Non-nucleoside Reverse Transcriptase Inhibitors: Implications for Current ART Strategies

Author

Vos, Wilhelm A. J. W., primary, Vadaq, Nadira, additional, Matzaraki, Vasiliki, additional, Otten, Twan, additional, Groenendijk, Albert L., additional, Blaauw, Marc J. T., additional, van Eekeren, Louise E., additional, Brinkman, Kees, additional, de Mast, Quirijn, additional, Riksen, Niels P., additional, Stalenhoef, Anton F. H., additional, van Lunzen, Jan, additional, van der Ven, Andre J. A. M., additional, Blok, Willem L., additional, and Stalenhoef, Janneke E., additional

Published
2024
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2. The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

Author

Hegele, Robert A, Ginsberg, Henry N, Chapman, M John, Nordestgaard, Børge G, Kuivenhoven, Jan Albert, Averna, Maurizio, Borén, Jan, Bruckert, Eric, Catapano, Alberico L, Descamps, Olivier S, Hovingh, G Kees, Humphries, Steve E, Kovanen, Petri T, Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G, Raal, Frederick J, Ray, Kausik K, Santos, Raul D, Stalenhoef, Anton F H, Stroes, Erik, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Watts, Gerald F, and Wiklund, Olov

Published
2014
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7. Casus 9 – Antwoord

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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8. Casus 8 – Antwoord

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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9. Casus 6 – Antwoord

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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10. Casus 3

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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11. Casus 2

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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12. TLR4 Polymorphisms, Infectious Diseases, and Evolutionary Pressure during Migration of Modern Humans

Author

Ferwerda, Bart, McCall, Matthew B. B., Alonso, Santos, Giamarellos-Bourboulis, Evangelos J., Mouktaroudi, Maria, Izagirre, Neskuts, Syafruddin, Din, Kibiki, Gibson, Cristea, Tudor, Hijmans, Anneke, Hamann, Lutz, Israel, Shoshana, ElGhazali, Gehad, Troye-Blomberg, Marita, Kumpf, Oliver, Maiga, Boubacar, Dolo, Amagana, Doumbo, Ogobara, Hermsen, Cornelus C., Stalenhoef, Anton F. H., van Crevel, Reinout, Brunner, Han G., Oh, Djin-Ye, Schumann, Ralf R., de la Rúa, Concepcion, Sauerwein, Robert, Kullberg, Bart-Jan, van der Ven, André J. A. M., van der Meer, Jos W. M., and Netea, Mihai G.

Published
2007
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13. Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

Author

Cuchel, Marina, Bruckert, Eric, Ginsberg, Henry N., Raal, Frederick J., Santos, Raul D., Hegele, Robert A., Kuivenhoven, Jan Albert, Nordestgaard, Børge G., Descamps, Olivier S., Steinhagen-Thiessen, Elisabeth, Tybjærg-Hansen, Anne, Watts, Gerald F., Averna, Maurizio, Boileau, Catherine, Borén, Jan, Catapano, Alberico L., Defesche, Joep C., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G., Ray, Kausik K., Stalenhoef, Anton F. H., Stroes, Erik, Taskinen, Marja-Riitta, Wiegman, Albert, Wiklund, Olov, Chapman, M. John, Cuchel, Marina, Bruckert, Eric, Chapman, M. John, Descamps, Olivier S., Ginsberg, Henry N., Hegele, Robert A., Kuivenhoven, Jan Albert, Nordestgaard, Børge G., Raal, Frederick J., Santos, Raul D., Steinhagen-Thiessen, Elisabeth, Tybjærg-Hansen, Anne, Watts, Gerald F., Chapman, M. John, Ginsberg, Henry N., Averna, Maurizio, Boileau, Catherine, Borén, Jan, Catapano, Alberico L., Defesche, Joep C., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G., Ray, Kausik K., Stalenhoef, Anton F. H., Stroes, Erik, Taskinen, Marja-Riitta, Wiegman, Albert, and Wiklund, Olov

Published
2014
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15. Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

Author

Wiegman, Albert, Gidding, Samuel S., Watts, Gerald F., Chapman, M. John, Ginsberg, Henry N., Cuchel, Marina, Ose, Leiv, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Alberico L., Defesche, Joep C., Descamps, Olivier S., Hegele, Robert A., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Kuivenhoven, Jan Albert, Masana, Luis, Nordestgaard, Børge G., Pajukanta, Päivi, Parhofer, Klaus G., Raal, Frederick J., Ray, Kausik K., Santos, Raul D., Stalenhoef, Anton F.H., Steinhagen- Thiessen, Elisabeth, Stroes, Erik S., Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Wiklund, Olov, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Alberico L., Chapman, M. John, Cuchel, Marina, Defesche, Joep C., Descamps, Olivier S., Gidding, Samuel S., Ginsberg, Henry N., Hegele, Robert A., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Kuivenhoven, Jan Albert, Masana, Luis, Nordestgaard, Børge G., Ose, Leiv, Pajukanta, Päivi, Parhofer, Klaus G., Raal, Frederick J., Ray, Kausik K, Santos, Raul D., Stalenhoef, Anton F. H., Steinhagen-Thiessen, Elisabeth, Stroes, Erik S., Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Watts, Gerald F., Wiegman, Albert, Wiklund, Olov, Gidding, Samuel S., Watts, Gerald F., Chapman, M. John, Ginsberg, Henry N., Cuchel, Marina, Ose, Leiv, Chapman, M. John, and Ginsberg, Henry N.

Published
2015
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16. Casus 40 – Antwoord

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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17. Casus 19

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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18. Casus 7 – Antwoord

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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19. Casus 5 – Antwoord

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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20. Casus 8

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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21. Casus 9

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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22. Casus 6

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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23. Casus 7

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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24. Casus 4

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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25. Casus 5

Author

de Graaf, Jacqueline, Stalenhoef, Anton F. H., de Graaf, Jacqueline, editor, and Stalenhoef, Anton F. H., editor

Published
2012
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26. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease : Consensus Statement of the European Atherosclerosis Society

Author

Nordestgaard, Børge G., Chapman, M. John, Humphries, Steve E., Ginsberg, Henry N., Masana, Luis, Descamps, Olivier S., Wiklund, Olov, Hegele, Robert A., Raal, Frederick J., Defesche, Joep C., Wiegman, Albert, Santos, Raul D., Watts, Gerald F., Parhofer, Klaus G., Hovingh, G. Kees, Kovanen, Petri T., Boileau, Catherine, Averna, Maurizio, Borén, Jan, Bruckert, Eric, Catapano, Alberico L., Kuivenhoven, Jan Albert, Pajukanta, Päivi, Ray, Kausik, Stalenhoef, Anton F. H., Stroes, Erik, Taskinen, Marja-Riitta, and Tybjærg-Hansen, Anne

Published
2013
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48. Two Genes That Map to the STSL Locus Cause Sitosterolemia: Genomic Structure and Spectrum of Mutations Involving Sterolin-1 and Sterolin-2, Encoded by ABCG5 and ABCG8, Respectively

Author

Lu, Kangmo, Lee, Mi-Hye, Hazard, Starr, Brooks-Wilson, Angela, Hidaka, Hideki, Kojima, Hideto, Ose, Leiv, Stalenhoef, Anton F. H., Mietinnen, Tatu, Bjorkhem, Ingemar, Bruckert, Eric, Pandya, Arti, Brewer, H. Bryan Jr., Salen, Gerald, Dean, Michael, Srivastava, Anand, and Patel, Shailendra B.

Subjects
Intestinal absorption -- Genetic aspects, Sterols -- Physiological aspects, Gene mutations -- Analysis, Protein metabolism disorders -- Genetic aspects, Biological sciences
Published
2001

49. Measurement of atherosclerosis progression

Author

Wierzbicki, Anthony S, Crook, Martin A, Reynolds, Timothy M, Mikhailidis, Dimitri P, Stalenhoef, Anton F H, Kastelein, John J P, Wissen, Sanne van, Smilde, Tineke J, Young, John H, Schminke, Ulf, Bond, M Gene, and Tang, Rong

Subjects
Atherosclerosis -- Development and progression
Published
2001

50. Familial hypercholesterolaemia in children and adolescents:gaining decades of life by optimizing detection and treatment

Author

Wiegman, Albert, Gidding, Samuel S, Watts, Gerald F, Chapman, M John, Ginsberg, Henry N, Cuchel, Marina, Ose, Leiv, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Alberico L, Defesche, Joep C, Descamps, Olivier S, Hegele, Robert A, Hovingh, G Kees, Humphries, Steve E, Kovanen, Petri T, Kuivenhoven, Jan Albert, Masana, Luis, Nordestgaard, Børge G, Pajukanta, Päivi, Parhofer, Klaus G, Raal, Frederick J, Ray, Kausik K, Santos, Raul D, Stalenhoef, Anton F H, Steinhagen-Thiessen, Elisabeth, Stroes, Erik S, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Wiklund, Olov, Wiegman, Albert, Gidding, Samuel S, Watts, Gerald F, Chapman, M John, Ginsberg, Henry N, Cuchel, Marina, Ose, Leiv, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Alberico L, Defesche, Joep C, Descamps, Olivier S, Hegele, Robert A, Hovingh, G Kees, Humphries, Steve E, Kovanen, Petri T, Kuivenhoven, Jan Albert, Masana, Luis, Nordestgaard, Børge G, Pajukanta, Päivi, Parhofer, Klaus G, Raal, Frederick J, Ray, Kausik K, Santos, Raul D, Stalenhoef, Anton F H, Steinhagen-Thiessen, Elisabeth, Stroes, Erik S, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, and Wiklund, Olov

Abstract

Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated early in childhood, individuals with FH can have normal life expectancy. This consensus paper aims to improve awareness of the need for early detection and management of FH children. Familial hypercholesterolaemia is diagnosed either on phenotypic criteria, i.e. an elevated low-density lipoprotein cholesterol (LDL-C) level plus a family history of elevated LDL-C, premature coronary artery disease and/or genetic diagnosis, or positive genetic testing. Childhood is the optimal period for discrimination between FH and non-FH using LDL-C screening. An LDL-C ≥5 mmol/L (190 mg/dL), or an LDL-C ≥4 mmol/L (160 mg/dL) with family history of premature CHD and/or high baseline cholesterol in one parent, make the phenotypic diagnosis. If a parent has a genetic defect, the LDL-C cut-off for the child is ≥3.5 mmol/L (130 mg/dL). We recommend cascade screening of families using a combined phenotypic and genotypic strategy. In children, testing is recommended from age 5 years, or earlier if homozygous FH is suspected. A healthy lifestyle and statin treatment (from age 8 to 10 years) are the cornerstones of management of heterozygous FH. Target LDL-C is <3.5 mmol/L (130 mg/dL) if >10 years, or ideally 50% reduction from baseline if 8–10 years, especially with very high LDL-C, elevated lipoprotein(a), a family history of premature CHD or other cardiovascular risk factors, balanced against the long-term risk of treatment side effects. Identifying FH early and optimally lowering LDL-C over the lifespan reduces cumulative LDL-C burden and offers health and socioeconomic benefits. To drive policy change for timely detection and management, we call for further studies in the young. Increased awareness, early identification, and optimal treatment from childhood are critical to adding decades of healthy life, Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated early in childhood, individuals with FH can have normal life expectancy. This consensus paper aims to improve awareness of the need for early detection and management of FH children. Familial hypercholesterolaemia is diagnosed either on phenotypic criteria, i.e. an elevated low-density lipoprotein cholesterol (LDL-C) level plus a family history of elevated LDL-C, premature coronary artery disease and/or genetic diagnosis, or positive genetic testing. Childhood is the optimal period for discrimination between FH and non-FH using LDL-C screening. An LDL-C ≥5 mmol/L (190 mg/dL), or an LDL-C ≥4 mmol/L (160 mg/dL) with family history of premature CHD and/or high baseline cholesterol in one parent, make the phenotypic diagnosis. If a parent has a genetic defect, the LDL-C cut-off for the child is ≥3.5 mmol/L (130 mg/dL). We recommend cascade screening of families using a combined phenotypic and genotypic strategy. In children, testing is recommended from age 5 years, or earlier if homozygous FH is suspected. A healthy lifestyle and statin treatment (from age 8 to 10 years) are the cornerstones of management of heterozygous FH. Target LDL-C is <3.5 mmol/L (130 mg/dL) if >10 years, or ideally 50% reduction from baseline if 8-10 years, especially with very high LDL-C, elevated lipoprotein(a), a family history of premature CHD or other cardiovascular risk factors, balanced against the long-term risk of treatment side effects. Identifying FH early and optimally lowering LDL-C over the lifespan reduces cumulative LDL-C burden and offers health and socioeconomic benefits. To drive policy change for timely detection and management, we call for further studies in the young. Increased awareness, early identification, and optimal treatment from childhood are critical to adding decades of healthy li

Published
2015

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