1. Evaluation of vitamin B12 monitoring in patients on metformin in urban ambulatory care settings
- Author
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Michael P. Conley, Kelsey B Sheehan, Jessica M Ryan, Debra J. Reid, Carla Bouwmeester, and Stacy L Longo
- Subjects
Pharmaceutical Science ,lcsh:RS1-441 ,Pharmacy ,Type 2 diabetes ,mesh:Metformin ,030226 pharmacology & pharmacy ,mesh:Diabetes Mellitus ,0302 clinical medicine ,Prevalence ,mesh:Practice ,mesh:Retrospective Studies ,Original Research ,Practice ,Health Knowledge ,mesh:Attitudes ,Metformin ,mesh:Vitamin B 12 ,Vitamin B 12 ,mesh:Prevalence ,mesh:United States ,Vitamin B12 Deficiency ,Type 2 ,medicine.drug ,medicine.medical_specialty ,mesh:Health Knowledge ,lcsh:Pharmacy and materia medica ,03 medical and health sciences ,Ambulatory care ,Internal medicine ,Diabetes mellitus ,mesh:Type 2 ,medicine ,Diabetes Mellitus ,Vitamin B12 ,Medical prescription ,Quality of Health Care ,Retrospective Studies ,Health Knowledge Attitudes Practice ,mesh:Vitamin B 12 Deficiency ,business.industry ,lcsh:RM1-950 ,nutritional and metabolic diseases ,Vitamin B 12 Deficiency ,Diabetes Mellitus Type 2 ,medicine.disease ,United States ,Peripheral neuropathy ,lcsh:Therapeutics. Pharmacology ,Concomitant ,Attitudes ,mesh:Quality of Health Care ,business - Abstract
Background: Previous studies linked metformin use to vitamin B12 deficiency and demonstrated that the prevalence of vitamin B12 monitoring remains low. Objective: This study aimed to assess the occurrence of monitoring vitamin B12 levels in a diverse population. Methods: This was a retrospective chart review of adult patients with type 2 diabetes on metformin doses ≥ 1000 mg for ≥ 6 months at five Federally Qualified Health Centers (FQHC) and one Program of All-Inclusive Care for the Elderly (PACE). Charts were reviewed for occurrence of monitoring vitamin B12 levels in the past 5 years. Data collected included patient demographics, laboratory data, other potential vitamin B12 level lowering agents, active prescription for vitamin B12 supplementation, concomitant diabetes medications and metformin total daily dose. Results: Of the 322 patients included, 25% had a vitamin B12 level measured in the previous five years. Among the patients with a vitamin B12 level, 87.7% were within the normal range (>350 pg/mL), 11.1% were low (200-300 pg/mL), and only one patient (1.2%) was deficient (
- Published
- 2019