11 results on '"Stachel I"'
Search Results
2. Searches for transverse momentum dependent flow vector fluctuations in Pb-Pb and p-Pb collisions at the LHC
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Acharya, S. Adamova, D. Adolfsson, J. Aggarwal, M. M. and Rinella, G. Aglieri Agnello, M. Agrawal, N. Ahammed, Z. and Ahmad, N. Ahn, S. U. Aiola, S. Akindinov, A. Alam, S. N. and Alba, J. L. B. Albuquerque, D. S. D. Aleksandrov, D. and Alessandro, B. Molina, R. Alfaro Alici, A. Alkin, A. and Alme, J. Alt, T. Altenkamper, L. Altsybeev, I. Prado, C. Alves Garcia Andrei, C. Andreou, D. Andrews, H. A. and Andronic, A. Anguelov, V. Anson, C. Anticic, T. and Antinori, F. Antonioli, P. Anwar, R. Aphecetche, L. and Appelshaeuser, H. Arcelli, S. Arnaldi, R. Arnold, O. W. and Arsene, I. C. Arslandok, M. Audurier, B. Augustinus, A. and Averbeck, R. Azmi, M. D. Badala, A. Baek, Y. W. and Bagnasco, S. Bailhache, R. Baa, R. Baldisseri, A. Ball, M. Bara, R. C. Barbano, A. M. Barbera, R. Barile, F. and Barioglio, L. Barnafoldi, G. G. Barnby, L. S. Barret, V. and Bartalini, P. Barth, K. Bartsch, E. Basile, M. Bastid, N. Basu, S. Bathen, B. Batigne, G. Batyunya, B. and Batzing, P. C. Bearden, I. G. Beck, H. Bedda, C. Behera, N. K. Belikov, I. Bellini, F. Bello Martinez, H. and Bellwied, R. Beltran, L. G. E. Belyaev, V. Bencedi, G. and Beole, S. Bercuci, A. Berdnikov, Y. Berenyi, D. Bertens, R. A. Berzano, D. Betev, L. Bhasin, A. Bhat, I. R. and Pia, A. K. Bhati Bhattacharjee, B. Bhom, J. Bianchi, L. and Bianchi, N. Bianchin, C. Bielcik, J. Bielcikova, J. and Bilandzic, A. Biro, G. Biswas, R. Biswas, S. Blair, J. T. Blau, D. Blume, C. Boca, G. Bock, F. Bogdanov, A. and Boldizsar, L. Bombara, M. Bonomi, G. Bonora, M. and Book, J. Borel, H. Borissov, A. Borri, M. Botta, E. and Bourjau, C. Bratrud, L. Braun-Munzinger, P. Bregant, M. and Broker, T. A. Broz, M. Brucken, E. J. Bruna, E. Bruno, G. E. Budnikov, D. Buesching, H. Bufalino, S. Buhler, P. and Buncic, P. Busch, O. Buthelezi, Z. Butt, J. B. and Buxton, J. T. Cabala, J. Caffarri, D. Caines, H. Caliva, A. Calvo Villar, E. Camerini, P. Capon, A. A. Carena, F. and Carena, W. Carnesecchi, F. Castellanos, J. Castillo and Castro, A. J. Casula, E. A. R. Ceballos Sanchez, C. Cerello, P. Chandra, S. Chang, B. Chapeland, S. Chartier, M. and Charvet, J. L. Chattopadhyay, S. Chattopadhyay, S. Chauvin, A. Cherney, M. Cheshkov, C. Cheynis, B. Barroso, V. Chibante Chinellato, D. D. Cho, S. Chochula, P. Choi, K. and Chojnacki, M. Choudhury, S. Chowdhury, T. Christakoglou, P. Christensen, C. H. Christiansen, P. Chujo, T. Chung, S. U. Cicalo, C. Cifarelli, L. Cindolo, F. Cleymansl, J. and Colamaria, F. Colella, D. Collu, A. Colocci, M. and Concas, M. Balbastre, G. Conesa del Valle, Z. Conesa and Connors, M. E. Contreras, J. G. Cormier, T. M. Corrales Morales, Y. Cortes Maldonado, I. Cortese, P. Cosentino, M. R. Costa, F. Costanza, S. Crkovska, J. Crochet, P. and Cuautle, E. Cunqueiro, L. Dahrns, T. Dainese, A. and Danisch, M. C. Danu, A. Das, D. Das, I. Das, S. and Dash, A. Dash, S. De, S. De Caro, A. de Cataldo, G. and de Conti, C. de Cuveland, J. De Falco, A. De Gruttola, D. and De Marco, N. De Pasquale, S. De Souza, R. D. Degenhardt, H. F. Deisting, A. Deloff, A. Deplano, C. Dhankher, P. and Di Bari, D. Di Mauro, A. Di Nezza, P. Di Ruzza, B. and Diaz Corchero, M. A. Dietel, T. Dillenseger, P. Divia, R. and Djuvsland, O. Dobrin, A. Gimenez, D. Domenicis Doenigus, B. Dordic, O. Doremalen, L. V. V. Drozhzhova, T. Dubey, A. K. Dubla, A. Ducroux, L. Duggal, A. K. Dupieux, P. and Ehlers, R. J. Elia, D. Endress, E. Engel, H. Epple, E. Erazmus, B. Erhardt, F. Espagnon, B. Esumi, S. and Eulisse, G. Eum, J. Evans, D. Evdokimov, S. Fabbietti, L. Faivre, J. Fantoni, A. Fase, M. Feldkamp, L. and Feliciello, A. Feofilov, G. Ferencei, J. Fernandez Tellez, A. Ferreiro, E. G. Ferretti, A. Festanti, A. Feuillard, V. J. G. Figie, J. Figueredo, M. A. S. Filchagin, S. and Finogeev, D. Fionda, F. M. Fiore, E. M. Floris, M. and Foertsch, S. Foka, P. Fokin, S. Fragiacomo, E. and Francescon, A. Francisco, A. Frankenfeld, U. Fronze, G. G. and Fuchs, U. Furget, C. Furs, A. Girard, M. Fusco and Gaardhoje, J. J. Gagliardi, M. Gago, A. M. Gajdosova, K. and Gallio, M. Galvan, C. D. Ganoti, P. Gao, C. Garabatos, C. Garcia-Solis, E. Garg, K. Garg, P. Gargiulo, C. and Gasik, P. Gauger, E. F. Ducati, M. B. Gay Germain, M. and Ghosh, J. Ghosh, P. Ghosh, S. K. Gianotti, P. and Giubellino, P. Giubilato, P. Gladysz-Dziadus, E. Glassel, P. and Gomez Coral, D. M. Ramirez, A. Gomez Gonzalez, A. S. and Gonzalez, V. Gonzalez-Zamoram, P. Gorbunov, S. Gorlich, L. and Gotovac, S. Grabski, V. Graczykowski, L. K. Graham, K. L. Greiner, L. Grelli, A. Grigoras, C. Grigoriev, V. and Grigoryan, A. Grigoryan, S. Grion, N. Gronefeld, J. M. and Grosa, F. Grosse-Oetringhaus, J. F. Grosso, R. Gruber, L. and Guber, F. Guernane, R. Guerzoni, B. Gulbrandsen, K. and Gunji, T. Gupta, A. Gupta, R. Guzman, I. B. Haake, R. and Hadjidakis, C. Hamagaki, H. Hamar, G. Hamon, J. C. and Haque, M. R. Harris, J. W. Harton, A. Hassan, H. and Hatzifotiadou, D. Hayashi, S. Heckel, S. T. Hellbaer, E. and Helstrup, H. Herghelegiu, A. Herrera Corral, G. Herrmann, F. and Hess, B. A. Hetland, K. F. Hillemanns, H. Hills, C. and Hippolyte, B. Hladky, J. Hohlweger, B. Horak, D. and Hornungl, S. Hosokawa, R. Hristov, P. Hughes, C. and Humanic, T. J. Hussain, N. Hussain, T. Hutter, D. Hwang, D. S. Buitron, S. A. Iga Ilkaev, R. Inaba, M. Ippolitov, M. Irfan, M. Isakv, V. Ivanov, M. Ivanov, V. and Izucheev, V. Jacak, B. Jacazio, N. Jacobs, P. M. Jadhav, M. B. Jadlovska, S. Jadlovsky, J. Jaelani, S. Jahnke, C. and Jakubowska, M. J. Janik, M. A. Jayarathna, P. H. S. Y. and Jena, C. Jena, S. Jercicm, M. Bustamante, R. T. Jimenez and Jones, P. G. Jusko, A. Kalinak, P. Kalweit, A. Kang, J. H. Kaplin, V. Kar, S. Uysal, A. Karasu Karavichev, . and Karavicheva, T. Karayan, L. Karczmarczyk, P. Karpechev, E. and Kebschu, U. Keide, R. Keijdener, D. L. D. Keil, M. and Ketzer, B. Khabanova, Z. Khan, P. Khan, S. A. and Khanzadeev, A. Kharlov, Y. Khatun, A. Khuntia, A. and Kielbowicz, M. M. Kileng, B. Kim, B. Kim, D. Kim, D. W. and Kim, D. J. Kim, H. Kim, J. S. Kim, J. Kim, M. and Kim, M. Kim, S. Kim, T. Kirsch, S. Kise, I. Kiselev, S. Kisiel, A. Kiss, G. Klay, J. L. Klein, C. Klein, J. Klein-Boesing, C. Klewin, S. Kluge, A. Knichel, M. L. and Knospe, A. G. Kobdaj, C. Kofarago, M. Kolleggerl, T. and Kolojvari, A. Kondratiev, V. Kondratyeva, N. Kondratyuk, E. and Konevskikh, A. Konyushikhin, M. Kopcik, M. Kourl, M. and Kouzinopoulos, C. Kovalenko, O. Kovalenko, V. Kowalski, M. and Meethaleveedu, G. Koyithatta Kralik, I. Kraveakova, A. and Krivda, M. Krizek, F. Kryshen, E. Krzewicki, M. Kubera, A. M. Kucera, V. Kuhn, C. Kuijer, P. G. Kumarl, A. and Kumar, J. Kumar, L. Kumar, S. Kundu, S. Kurashvili, P. and Kurepin, A. Kurepin, A. B. Kuryakin, A. Kushpi, S. and Kweon, M. J. Kwon, Y. La Pointe, S. L. La Rocca, P. and Fernandes, C. Lagana Lai, Y. S. Lakomov, I. Langoy, R. and Lapidus, K. Lara, C. Lardeux, A. Lattuca, A. Laudi, E. and Lavicka, R. Lazaridis, L. Lea, R. Leardini, L. Lee, S. Lehas, F. Lehner, S. Lehrbach, J. Lemmon, R. C. and Lenti, V. Leogrande, E. Monzon, T. Leon Levai, P. Li, S. and Li, X. Lien, J. Lietava, R. Lim, B. Lindal, S. and Lindenstruth, V. Lindsay, S. W. Lipprnann, C. Lisa, M. A. and Litichevskyi, V. Ljunggren, H. M. Llope, W. J. Lodato, D. F. Loenne, P. I. Loginov, V. Loizides, C. Loncar, P. and Lopez, X. Lopez Torres, E. Lowe, A. Luettig, P. and Lunardon, M. Luparello, G. Lupi, M. Lutz, T. H. and Maevskaya, A. Mager, M. Mahajan, S. Mahmood, S. M. and Maire, A. Majka, R. D. Malaev, M. Malinina, L. and Mal'Kevich, D. Malzacher, P. Mamonov, A. Manko, V. and Manso, F. Manzari, V. Mao, Y. Marchisone, M. Mares, J. and Margagliotti, G. V. Margotti, A. Margutti, J. Marin, A. and Markert, C. Marquard, M. Martin, N. A. Martinengo, P. and Martinez, J. A. L. Martinez, M. I. Garcia, G. Martinez and Pedreira, M. Martinez Mas, A. Masciocchi, S. Masera, M. and Masoni, A. Masson, E. Mastroserio, A. Mathis, A. M. and Matyja, A. Mayer, C. Mazer, J. Mazzilli, M. Mazzoni, M. A. Meddi, F. Melikyan, Y. Menchaca-Rocha, A. Meninno, E. and Perez, J. Mercado Meres, M. Mhlanga, S. Miake, Y. and Mieskolainen, M. M. Mihaylov, D. Mihaylov, D. L. Mikhaylov, K. Milano, L. Milosevic, J. Mischke, A. Mishra, A. N. and Miskowiec, D. Mitra, J. Mitu, C. M. Mohammadi, N. and Mohanty, B. Khan, M. Mohisin Montesth, E. De Godoy, D. A. Moreira Moreno, L. A. P. Moretto, S. Morreale, A. and Morsch, A. Muccifora, V. Mudnic, E. Muehlheirn, D. and Muhuri, S. Mukherjee, M. Mulligan, J. D. Munhoz, M. G. and Muenning, K. Munzer, R. H. Murakarni, H. Murray, S. and Musa, L. Musinsky, J. Myers, C. J. Myrcha, J. W. Naik, B. Nair, R. Nandi, B. K. Nania, R. Nappi, E. and Narayan, A. Naru, M. U. da Luz, H. Natal Nattrass, C. and Navarro, S. R. Nayak, K. Nayak, R. Nayak, T. K. and Nazarenko, S. Nedosekin, A. De Oliveira, R. A. Negrao and Nellen, L. Nesbo, S. V. Ng, F. Nicassio, M. Niculescu, M. Niedziela, J. Nielsen, B. S. Nikolaev, S. Nikulin, S. and Nikulin, V. Nobuhiro, A. Noferini, F. Nomokonov, P. and Nooren, G. Noris, J. C. C. Norman, J. Nyanin, A. and Nystrand, J. Oeschler, H. Oh, S. Ohlson, A. Okubo, T. and Olah, L. Oleniacz, J. Da Silva, A. C. Oliveira Oliver, M. H. Onderwaater, J. Oppedisano, C. Orava, R. Oravec, M. Velasquez, A. Ortiz Oskarsson, A. Otwinowski, J. and Oyama, K. Pachmayer, Y. Pacik, V. Pagano, D. Pagano, P. and Paic, G. Palni, P. Pan, J. Pandey, A. K. Panebianco, S. Papikyan, V. Pappalardo, G. S. Pareek, P. Parke, J. and Parmar, S. Passfeld, A. Pathak, S. P. Paticchio, V. and Patra, R. N. Pau, B. Pei, H. Peitzmann, T. Peng, X. and Pereira, L. G. Da Costa, H. Pereira Peresunko, D. Lezama, E. Perez Peskov, V. Pestov, Y. Petracek, V. Petrov, V. and Petrovici, M. Petta, C. Pezzi, R. P. Piano, S. Pikna, M. and Pillot, P. Pimente, L. O. D. L. Pinazza, O. Pinsky, L. and Piyarathna, D. B. Ploskon, M. Planinic, M. Pliquett, F. and Pluta, J. Pochybova, S. Podesta-Lerma, P. L. M. and Poghosyan, M. G. Polichtchouk, B. Poljak, N. Poonsawat, W. and Pop, A. Poppenborg, H. Porteboeuf-Houssais, S. Porter, J. Pozdniakov, V. Prasad, S. K. Preghenella, R. Prino, F. Pruneau, C. A. Pshenichnov, I. Puccio, M. Puddu, G. and Pujahari, P. Punin, V. Putschke, J. Rachevski, A. and Raha, S. Rajput, S. Rak, J. Rakotozafindrabe, A. and Ramello, L. Rami, F. Rana, D. B. Raniwalal, R. Raniwala, S. Rasanen, S. S. Rascanu, B. T. Rathee, D. Ratza, V. and Ravasenga, I. Read, K. F. Redlich, K. Rehman, A. and Reichelt, P. Reidt, F. Ren, X. Renfordt, R. Reolon, A. R. Reshetin, A. Reygers, K. Riabov, V. Ricci, R. A. and Richert, T. Richter, M. Riedler, P. Riegler, W. Riggi, F. C. Rodriguez Cahuantzi, M. Roed, K. Rogochaya, E. and Rohr, D. Rohrich, D. Rokita, P. S. Ronchetti, F. Rosas, E. D. Rosnet, P. Rossi, A. Rotondi, A. Roukoutakis, F. and Roy, A. Roy, C. Roy, P. Rubio Montero, A. J. Rueda, O. V. Rui, R. Rumyantsev, B. Rustamov, A. Ryabinkin, E. and Ryabov, Y. Rybicki, A. Saarinen, S. Sadhu, S. and Sadovsky, S. Safarik, K. Saha, S. K. Sahlmuller, B. and Sahoo, B. Sahoo, P. Sahoo, R. Sahoo, S. Sahu, P. K. and Saini, J. Sakai, S. Saleh, M. A. Salzwedel, J. Sambyall, S. Samsonov, V. Sandoval, A. Sarkar, D. Sarkar, N. and Sarma, P. Sas, M. H. P. Scapparone, E. Scarlassara, F. and Scharenberg, R. P. Scheid, H. S. Schiaua, C. Schicker, R. and Schmidt, C. Schmidtl, H. R. Schmidt, M. O. Schmidt, M. and Schuchmann, S. Schukraft, J. Schutz, Y. Schwarz, K. and Schweda, K. Scioli, G. Scomparin, E. Scott, R. Sefcik, M. Seger, J. E. Sekiguchi, Y. Sekihata, D. Selyuzhenkov, I. Senosi, K. Senyukov, S. Serradilla, E. Sett, P. and Sevcenco, A. Shabanov, A. Shabetai, A. Shahoyan, R. and Shaikh, W. Shangaraev, A. Sharmaror, A. Sharmal, A. and Sharrna, M. Sharrna, M. Sharma, N. Sheikh, A. I. and Shigaki, K. Shou, Q. Shtejer, K. Sibiriak, Y. Siddhanta, S. Sielewicz, K. M. Siemiarczuk, T. Silvermyr, D. and Silvestre, C. Simatovicl, G. Simonetti, G. Singaraju, R. and Singh, R. Singhal, V. Sinha, T. Sitar, B. Sitta, M. and Skaali, T. B. Slupecki, M. Smirnov, N. Snellings, R. J. M. and Snellman, T. W. Song, J. Song, M. Soramel, F. and Sorensen, S. Sozzil, F. Spiriti, E. Sputowska, I. and Srivastava, B. K. Stachel, I, J. Stan, I. Stankus, P. and Stenlund, E. Stocco, D. Strmen, P. Suaide, A. A. P. and Sugitate, T. Suire, C. Suleymanov, M. Suljic, M. and Sultanov, R. Sumbera, M. Sumowidagdo, S. Suzuki, K. and Swain, S. Szabo, A. Szarka, I. Tabassam, U. Takahashi, J. Tambave, G. J. Tanaka, N. Tarhini, M. Tariq, M. and Tarzila, M. G. Tauro, A. Tejeda Munoz, G. Telesca, A. and Terasaki, K. Terrevoli, C. Teyssier, B. Thakur, D. and Thakur, S. Thomas, D. Thoresen, F. Tieulent, R. and Tikhonov, A. Timmins, A. R. Toia, A. Tripathy, S. and Trogolo, S. Trombetta, G. Tropp, L. Trubnikov, V. and Trzaska, W. H. Trzeciak, B. A. Tsuji, T. Tumkin, A. and Turrisi, R. Tveter, T. S. Ullaland, K. Urnaka, E. N. and Uras, A. Usai, G. L. Utrobicicm, A. Vala, M. Van der Maare, J. Van Hoorne, J. W. van Leeuwen, M. Vanat, T. and Vande Vyvre, P. Varga, D. Vargas, A. Vargyas, M. Varma, R. Vasileiou, M. Vasiliev, A. Vauthier, A. Doce, O. Vazquez Vechernin, V. Veen, A. M. Velure, A. Vercellin, E. Vergara Limon, S. Vernet, R. Vertesi, R. Vickovic, L. and Vigolo, S. Viinikainen, J. Vilakazi, Z. Baillie, O. Villalobos Villatoro Tello, A. Vinogradov, A. Vinogradov, L. and Virgili, T. Vislavicius, V. Vodopyanov, A. Voelkl, M. A. and Voloshin, K. Voloshin, S. A. Volpe, G. von Haller, B. and Vorobyev, I. Voscek, D. Vranic, D. Vrlakova, J. and Wagner, B. Wang, H. Wang, M. Watanabe, D. Watanabe, Y. and Weber, M. Weberl, S. G. Weiser, D. F. Wenze, S. C. and Wessels, J. P. Westerhoff, U. Whiteheadl, A. M. Wiechula, J. and Wikne, J. Wilk, G. Wilkinson, J. Willems, G. A. and Williams, M. C. S. Willsher, E. Windelband, B. Witt, W. E. and Yalcin, S. Yamakawa, K. Yang, P. Yano, S. Yin, Z. and Yokoyama, H. Yoo, I. -K. Yoon, J. H. Yurchenko, V. and Zaccolo, V. Zaman, A. Zampolli, C. Zanoli, H. J. C. and Zardoshti, N. Zarochentsev, A. Zavada, P. Zaviyalov, N. and Zbroszczyk, H. Zhalov, M. Zhang, H. Zhang, X. Zhang, Y. and Zhang, C. Zhang, Z. Zhao, C. Zhigareva, N. Zhou, D. and Zhou, Y. Zhou, Z. Zhu, H. Zhu, J. Zhu, X. and Zichichi, A. Zimmermannl, A. Zimmermann, M. B. Zinovjev, G. and Zmeska, J. Zou, S. ALICE Collaboration
- Subjects
High Energy Physics::Experiment ,Nuclear Experiment - Abstract
The measurement of azimuthal correlations of charged particles is presented for Pb-Pb collisions at root S-NN 2.76 TeV and p-Pb collisions at root S-NN 5.02 TeV with the ALICE detector at the CERN Large Hadron Collider. These correlations are measured for the second, third and fourth order flow vector in the pseudorapidity region vertical bar eta vertical bar 0.8 as a function of centrality and transverse momentum pT using two observables, to search for evidence of PT-dependent flow vector fluctuations. For Ph-Ph collisions at 2.76 TeV, the measurements indicate that PT-dependent fluctuations are only present for the second order flow vector. Similar results have been found for p-Pb collisions at 5.02 TeV. These measurements are compared to hydrodynamic model calculations with event-by-event geometry fluctuations in the initial state to constrain the initial conditions and transport properties of the matter created in Ph-Ph and p-Pb collisions.
- Published
- 2017
3. Interferenz des Immediate Early Response-3 (IER3) Gens mit dem Transkriptionsfaktor Nuclear factor E2 related factor-2 (Nrf2): ein neuer Mechanismus der Karzinogenese
- Author
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Stachel, I, primary, Geismann, C, additional, Aden, K, additional, Bauer, I, additional, Rosenstiel, P, additional, Schreiber, S, additional, Arlt, A, additional, and Schäfer, H, additional
- Published
- 2013
- Full Text
- View/download PDF
4. Cross-linking of collagen with laccases and tyrosinases
- Author
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Jus, S., primary, Stachel, I., additional, Schloegl, W., additional, Pretzler, M., additional, Friess, W., additional, Meyer, M., additional, Birner-Gruenberger, R., additional, and Guebitz, G.M., additional
- Published
- 2011
- Full Text
- View/download PDF
5. Stabilization of collagen with biotechnological approaches
- Author
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Stachel, I., Schlögl, W., Frieß, W., Gübitz, G., and Michael Meyer
6. Unveiling the strong interaction among hadrons at the LHC
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Acharya, Shreyasi, Adamova, Dagmar, Ahn, Sang Un, Bhattacharjee, Buddhadeb, Yurchenko, Volodymyr, Zaccolo, Valentina, Zaman, Ali, Zampolli, Chiara, Correia Zanoli, Henrique Jose, Zardoshti, Nima, Zarochentsev, Andrey, Zavada, Petr, Zavyalov, Nikolay, Zbroszczyk, Hanna Paulina, Bianchi, Antonio, Zhalov, Mikhail, Zhang, Song, Zhang, Xiaoming, Zhang, Zuman, Zherebchevskii, Vladimir, Yu, Zhi, Zhou, Daicui, Zhou, You, Zhou, Zhuo, Zhu, Jianhui, Bianchi, Livio, Zhu, Ya, Zichichi, Antonino, Zinovjev, Gennady, Zurlo, Nicola, ALICE Collaboration, Bianchi, Nicola, Bielcik, Jaroslav, Bielcikova, Jana, Bilandzic, Ante, Biro, Gabor, Biswas, Rathijit, Biswas, Saikat, Akbar, Zaenal, Blair, Justin Thomas, Blau, Dmitry, Blume, Christoph, Boca, Gianluigi, Bock, Friederike, Bogdanov, Alexey, Boi, Stefano, Bok, Jeongsu, Boldizsar, Laszlo, Bolozdynya, Alexander, Akindinov, Alexander, Bombara, Marek, Bonomi, Germano, Borel, Herve, Borissov, Alexander, Bossi, Hannah, Botta, Elena, Bratrud, Lars, Braun-munzinger, Peter, Bregant, Marco, Broz, Michal, Al-turany, Mohammad, Bruna, Elena, Bruno, Giuseppe Eugenio, Buckland, Matthew Daniel, Budnikov, Dmitry, Buesching, Henner, Bufalino, Stefania, Bugnon, Ophelie, Buhler, Paul Alois, Buncic, Predrag, Buthelezi, Edith Zinhle, Alam, Sk Noor, Bashir Butt, Jamila, Bysiak, Sebastian Adam, Caffarri, Davide, Caliva, Alberto, Calvo Villar, Ernesto, Mejia Camacho, Juan Manuel, Soto Camacho, Rabi, Camerini, Paolo, De Moraes Canedo, Fabio, Capon, Aaron Allan, Silva De Albuquerque, Danilo, Carnesecchi, Francesca, Caron, Robin Albert Andre, Castillo Castellanos, Javier Ernesto, Castro, Andrew John, Casula, Ester Anna Rita, Catalano, Fabio, Ceballos Sanchez, Cesar, Chakraborty, Pritam, Chandra, Sinjini, Chang, Wan, Aleksandrov, Dmitry, Chapeland, Sylvain, Chartier, Marielle, Chattopadhyay, Subhasis, Chattopadhyay, Sukalyan, Chauvin, Alex Henri Jean, Cheshkov, Cvetan Valeriev, Cheynis, Brigitte, Chibante Barroso, Vasco Miguel, Dobrigkeit Chinellato, 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Shiming, Yuncu, Alperen, Acharya, S., Adamova, D., Adler, A., Adolfsson, J., Aggarwal, M. M., Rinella, G. A., Agnello, M., Agrawal, N., Ahammed, Z., Ahmad, S., Ahn, S. U., Akbar, Z., Akindinov, A., Al-Turany, M., Alam, S. N., Albuquerque, D. S. D., Aleksandrov, D., Alessandro, B., Alfanda, H. M., Molina, R. A., Ali, B., Ali, Y., Alici, A., Alizadehvandchali, N., Alkin, A., Alme, J., Alt, T., Altenkamper, L., Altsybeev, I., Anaam, M. N., Andrei, C., Andreou, D., Andronic, A., Angeletti, M., Anguelov, V., Anson, C., Anticic, T., Antinori, F., Antonioli, P., Apadula, N., Aphecetche, L., Appelshauser, H., Arcelli, S., Arnaldi, R., Arratia, M., Arsene, I. C., Arslandok, M., Augustinus, A., Averbeck, R., Aziz, S., Azmi, M. D., Badala, A., Baek, Y. W., Bagnasco, S., Bai, X., Bailhache, R., Bala, R., Balbino, A., Baldisseri, A., Ball, M., Balouza, S., Banerjee, D., Barbera, R., Barioglio, L., Barnafoldi, G. G., Barnby, L. S., Barret, V., Bartalini, P., Bartels, C., Barth, K., Bartsch, E., Baruffaldi, F., Bastid, N., Basu, S., Batigne, G., Batyunya, B., Bauri, D., Alba, J. L. B., Bearden, I. G., Beattie, C., Bedda, C., Behera, N. K., Belikov, I., Hechavarria, A. D. C. B., Bellini, F., Bellwied, R., Belyaev, V., Bencedi, G., Beole, S., Bercuci, A., Berdnikov, Y., Berenyi, D., Bertens, R. A., Berzano, D., Besoiu, M. G., Betev, L., Bhasin, A., Bhat, I. R., Bhat, M. A., Bhatt, H., Bhattacharjee, B., Bianchi, A., Bianchi, L., Bianchi, N., Bielcik, J., Bielcikova, J., Bilandzic, A., Biro, G., Biswas, R., Biswas, S., Blair, J. T., Blau, D., Blume, C., Boca, G., Bock, F., Bogdanov, A., Boi, S., Bok, J., Boldizsar, L., Bolozdynya, A., Bombara, M., Bonomi, G., Borel, H., Borissov, A., Bossi, H., Botta, E., Bratrud, L., Braun-Munzinger, P., Bregant, M., Broz, M., Bruna, E., Bruno, G. E., Buckland, M. D., Budnikov, D., Buesching, H., Bufalino, S., Bugnon, O., Buhler, P., Buncic, P., Buthelezi, Z., Butt, J. B., Bysiak, S. A., Caffarri, D., Caliva, A., Villar, E. C., Camacho, J. M. M., Camacho, R. S., Camerini, P., Canedo, F. D. M., Capon, A. A., Carnesecchi, F., Caron, R., Castellanos, J. C., Castro, A. J., Casula, E. A. R., Catalano, F., Sanchez, C. C., Chakraborty, P., Chandra, S., Chang, W., Chapeland, S., Chartier, M., Chattopadhyay, S., Chauvin, A., Cheshkov, C., Cheynis, B., Barroso, V. C., Chinellato, D. D., Cho, S., Chochula, P., Chowdhury, T., Christakoglou, P., Christensen, C. H., Christiansen, P., Chujo, T., Cicalo, C., Cifarelli, L., Cilladi, L. D., Cindolo, F., Ciupek, M. R., Clai, G., Cleymans, J., Colamaria, F., Colella, D., Collu, A., Colocci, M., Concas, M., Balbastre, G. C., del Valle, Z. C., Contin, G., Contreras, J. G., Cormier, T. M., Morales, Y. C., Cortese, P., Cosentino, M. R., Costa, F., Costanza, S., Crochet, P., Cuautle, E., Cui, P., Cunqueiro, L., Dabrowski, D., Dahms, T., Dainese, A., Damas, F. P. A., Danisch, M. 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R., Harlenderova, A., Harris, J. W., Harton, A., Hasenbichler, J. A., Hassan, H., Hassan, Q. U., Hatzifotiadou, D., Hauer, P., Havener, L. B., Hayashi, S., Heckel, S. T., Hellbar, E., Helstrup, H., Herghelegiu, A., Herman, T., Hernandez, E. G., Corral, G. H., Herrmann, F., Hetland, K. F., Hillemanns, H., Hills, C., Hippolyte, B., Hohlweger, B., Honermann, J., Horak, D., Hornung, A., Hornung, S., Hosokawa, R., Hristov, P., Huang, C., Hughes, C., Huhn, P., Humanic, T. J., Hushnud, H., Husova, L. A., Hussain, N., Hussain, S. A., Hutter, D., Iddon, J. P., Ilkaev, R., Ilyas, H., Inaba, M., Innocenti, G. M., Ippolitov, M., Isakov, A., Islam, M. S., Ivanov, M., Ivanov, V., Izucheev, V., Jacak, B., Jacazio, N., Jacobs, P. M., Jadlovska, S., Jadlovsky, J., Jaelani, S., Jahnke, C., Jakubowska, M. J., Janik, M. A., Janson, T., Jercic, M., Jevons, O., Jin, M., Jonas, F., Jones, P. G., Jung, J., Jung, M., Jusko, A., Kalinak, P., Kalweit, A., Kaplin, V., Kar, S., Uysal, A. K., Karatovic, D., Karavichev, O., Karavicheva, T., Karczmarczyk, P., Karpechev, E., Kazantsev, A., Kebschull, U., Keidel, R., Keil, M., Ketzer, B., Khabanova, Z., Khan, A. M., Khan, S., Khanzadeev, A., Kharlov, Y., Khatun, A., Khuntia, A., Kileng, B., Kim, B., Kim, D., Kim, D. J., Kim, E. J., Kim, H., Kim, J., Kim, J. S., Kim, M., Kim, S., Kim, T., Kirsch, S., Kisel, I., Kiselev, S., Kisiel, A., Klay, J. L., Klein, C., Klein, J., Klein, S., Klein-Bosing, C., Kleiner, M., Kluge, A., Knichel, M. L., Knospe, A. G., Kobdaj, C., Kohler, M. K., Kollegger, T., Kondratyev, A., Kondratyeva, N., Kondratyuk, E., Konig, J., Konigstorfer, S. A., Konopka, P. J., Kornakov, G., Koska, L., Kovalenko, O., Kovalenko, V., Kowalski, M., Kralik, I., Kravcakova, A., Kreis, L., Krivda, M., Krizek, F., Gajdosova, K. K., Kruger, M., Kryshen, E., Krzewicki, M., Kubera, A. M., Kucera, V., Kuhn, C., Kuijer, P. G., Kumar, L., Kundu, S., Kurashvili, P., Kurepin, A., Kurepin, A. 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A., Martinengo, P., Martinez, J. L., Martinez, M. I., Garcia, G. M., Masciocchi, S., Masera, M., Masoni, A., Massacrier, L., Masson, E., Mastroserio, A., Mathis, A. M., Matonoha, O., Matuoka, P. F. T., Matyja, A., Mayer, C., Mazzaschi, F., Mazzilli, M., Mazzoni, M. A., Mechler, A. F., Meddi, F., Melikyan, Y., Menchaca-Rocha, A., Mengke, C., Meninno, E., Menon, A. S., Meres, M., Mhlanga, S., Miake, Y., Micheletti, L., Migliorin, L. C., Mihaylov, D. L., Mikhaylov, K., Mishra, A. N., Miskowiec, D., Modak, A., Mohammadi, N., Mohanty, A. P., Mohanty, B., Khan, M. M., Moravcova, Z., Mordasini, C., Moreira De Godoy, D. A., Moreno, L. A. P., Morozov, I., Morsch, A., Mrnjavac, T., Muccifora, V., Mudnic, E., Muhlheim, D., Muhuri, S., Mulligan, J. D., Mulliri, A., Munhoz, M. G., Munzer, R. H., Murakami, H., Murray, S., Musa, L., Musinsky, J., Myers, C. J., Myrcha, J. W., Naik, B., Nair, R., Nandi, B. K., Nania, R., Nappi, E., Naru, M. U., Nassirpour, A. F., Nattrass, C., Nayak, R., Nayak, T. 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N., Uras, A., Usai, G. L., Vala, M., Valle, N., Vallero, S., van der Kolk, N., van Doremalen, L. V. R., van Leeuwen, M., Vyvre, P. V., Varga, D., Varga, Z., Varga-Kofarago, M., Vargas, A., Vasileiou, M., Vasiliev, A., Doce, O. V., Vechernin, V., Vercellin, E., Limon, S. V., Vermunt, L., Vernet, R., Vertesi, R., Vickovic, L., Vilakazi, Z., Baillie, O. V., Vino, G., Vinogradov, A., Virgili, T., Vislavicius, V., Vodopyanov, A., Volkel, B., Volkl, M. A., Voloshin, K., Voloshin, S. A., Volpe, G., von Haller, B., Vorobyev, I., Voscek, D., Vrlakova, J., Wagner, B., Weber, M., Weber, S. G., Wegrzynek, A., Wenzel, S. C., Wessels, J. P., Wiechula, J., Wikne, J., Wilk, G., Wilkinson, J., Willems, G. A., Willsher, E., Windelband, B., Winn, M., Witt, W. E., Wright, J. R., Wu, Y., Xu, R., Yalcin, S., Yamaguchi, Y., Yamakawa, K., Yang, S., Yano, S., Yin, Z., Yokoyama, H., Yoo, I. -K., Yoon, J. H., Yuan, S., Yuncu, A., Yurchenko, V., Zaccolo, V., Zaman, A., Zampolli, C., Zanoli, H. J. C., Zardoshti, N., Zarochentsev, A., Zavada, P., Zaviyalov, N., Zbroszczyk, H., Zhalov, M., Zhang, S., Zhang, X., Zhang, Z., Zherebchevskii, V., Zhi, Y., Zhou, D., Zhou, Y., Zhou, Z., Zhu, J., Zhu, Y., Zichichi, A., Zinovjev, G., Zurlo, N., Laboratoire de physique subatomique et des technologies associées (SUBATECH), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Département de Physique Nucléaire (ex SPhN) (DPHN), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique de Clermont (LPC), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Institut Pluridisciplinaire Hubert Curien (IPHC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ALICE, Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), S. 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Ryabov, A. Rybicki, H. Rytkonen, O. A. M. Saarimaki, R. Sadek, S. Sadhu, S. Sadovsky, K. Šafařík, S. K. Saha, B. Sahoo, P. Sahoo, R. Sahoo, S. Sahoo, P. K. Sahu, J. Saini, S. Sakai, S. Sambyal, V. Samsonov, D. Sarkar, N. Sarkar, P. Sarma, V. M. Sarti, M. H. P. Sas, E. Scapparone, J. Schambach, H. S. Scheid, C. Schiaua, R. Schicker, A. Schmah, C. Schmidt, H. R. Schmidt, M. O. Schmidt, M. Schmidt, N. V. Schmidt, A. R. Schmier, J. Schukraft, Y. Schutz, K. Schwarz, K. Schweda, G. Scioli, E. Scomparin, J. E. Seger, Y. Sekiguchi, D. Sekihata, I. Selyuzhenkov, S. Senyukov, D. Serebryakov, A. Sevcenco, A. Shabanov, A. Shabetai, R. Shahoyan, W. Shaikh, A. Shangaraev, A. Sharma, A. Sharma, H. Sharma, M. Sharma, N. Sharma, S. Sharma, O. Sheibani, K. Shigaki, M. Shimomura, S. Shirinkin, Q. Shou, Y. Sibiriak, S. Siddhanta, T. Siemiarczuk, D. Silvermyr, G. Simatovic, G. Simonetti, B. Singh, R. Singh, R. Singh, R. Singh, V. K. Singh, V. Singhal, T. Sinha, B. Sitar, M. Sitta, T. B. Skaali, M. 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Zhou, Y. Zhou, Z. Zhou, J. Zhu, Y. Zhu, A. Zichichi, G. Zinovjev & N. Zurlo, Helsinki Institute of Physics, Sub Subatomic Physics (SAP), Afd Subatomic Physics (SAP), Sub Algemeen Physics Education, and Subatomic Physics
- Subjects
EXCHANGE-POTENTIAL APPROACH ,Strange quark ,ALICE Collaboration ,Hadron ,Nuclear Theory ,Strong interaction ,hadron collisions ,Position and momentum space ,hiukkasfysiikka ,nucl-ex ,7. Clean energy ,01 natural sciences ,VDP::Fysikk: 430 ,High Energy Physics - Experiment ,High Energy Physics - Experiment (hep-ex) ,Hadron-Hadron scattering (experiments) ,scattering [hadron] ,p p scattering ,[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex] ,scattering [p p] ,Nuclear Experiment (nucl-ex) ,Experimental nuclear physics ,NUCLEON ,Nuclear Experiment ,VDP::Physics: 430 ,Physics ,Multidisciplinary ,Large Hadron Collider ,strong interaction ,lattice [space-time] ,Publisher Correction ,PRIRODNE ZNANOSTI. Fizika ,BARYON-BARYON SCATTERING ,CERN LHC Coll ,LHC ,ddc:500 ,Nucleon ,Particle Physics - Experiment ,discrete [space-time] ,Quark ,Particle physics ,CERN Lab ,General Science & Technology ,FOS: Physical sciences ,short-range ,Hadron, strong interaction, LHC ,114 Physical sciences ,Fysikk: 430 [VDP] ,Article ,hadron scattering ,quark ,ultrarelativistic proton–proton collisions, LHC, ALICE ,0103 physical sciences ,Nuclear Physics - Experiment ,General ,010306 general physics ,Physics: 430 [VDP] ,interaction [hadron hadron] ,hep-ex ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,effect [strong interaction] ,hadron-hadron interaction ,strong interaction: effect ,space-time: discrete ,space-time: lattice ,correlation ,NATURAL SCIENCES. Physics ,Baryon ,Hypernuclei ,Neutron Stars ,Strangeness ,Physics::Accelerator Physics ,High Energy Physics::Experiment ,hadron ,Experimental particle physics - Abstract
One of the key challenges for nuclear physics today is to understand from first principles the effective interaction between hadrons with different quark content. First successes have been achieved using techniques that solve the dynamics of quarks and gluons on discrete space-time lattices1,2. Experimentally, the dynamics of the strong interaction have been studied by scattering hadrons off each other. Such scattering experiments are difficult or impossible for unstable hadrons3–6 and so high-quality measurements exist only for hadrons containing up and down quarks7. Here we demonstrate that measuring correlations in the momentum space between hadron pairs8–12 produced in ultrarelativistic proton–proton collisions at the CERN Large Hadron Collider (LHC) provides a precise method with which to obtain the missing information on the interaction dynamics between any pair of unstable hadrons. Specifically, we discuss the case of the interaction of baryons containing strange quarks (hyperons). We demonstrate how, using precision measurements of proton–omega baryon correlations, the effect of the strong interaction for this hadron–hadron pair can be studied with precision similar to, and compared with, predictions from lattice calculations13,14. The large number of hyperons identified in proton–proton collisions at the LHC, together with accurate modelling15 of the small (approximately one femtometre) inter-particle distance and exact predictions for the correlation functions, enables a detailed determination of the short-range part of the nucleon-hyperon interaction., Correlations in momentum space between hadrons created by ultrarelativistic proton–proton collisions at the CERN Large Hadron Collider provide insights into the strong interaction, particularly the short-range dynamics of hyperons—baryons that contain strange quarks.
- Published
- 2020
7. Green Sorbitol- and Isosorbide-Based Flame Retardants for Cotton Fabrics.
- Author
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De Smet D, Wéry M, Bader M, Stachel I, Meyer M, and Vanneste M
- Abstract
Flame retardancy is often required in various textile applications. Halogenated flame retardants (FR) are commonly used since they have good FR performance. Several of these components are listed under REACH. Halogen-free FR compounds have been developed as alternatives. So far, not many biobased FR have made it to the market and are being applied in the textile sector, leaving great opportunities since biobased products are experiencing a renaissance. In this study, renewable FR based on sorbitol and isosorbide were synthesised. The reaction was performed in the melt. The resulting biobased FR were characterised via FT-IR, thermogravimetric analysis (TGA) and X-ray fluorescence (XRF). Cotton fabrics functionalized with the developed biobased FR passed ISO 15025 FR test. After washing, the FR properties of the fabrics decreased (longer afterflame and afterglow time) but still complied with ISO 15025, indicating the biobased FR were semi-permanent. The amount of residue of modified sorbitol and isosorbide measured at 600 °C in air was 31% and 27%, respectively. Cotton treated with biobased modified FR showed no ignition during cone calorimetry experiments, indicating a flame retardancy. Furthermore, a charring of the FR containing samples was observed by means of cone calorimetry and TGA measurements.
- Published
- 2021
- Full Text
- View/download PDF
8. Modulation of nuclear factor E2-related factor-2 (Nrf2) activation by the stress response gene immediate early response-3 (IER3) in colonic epithelial cells: a novel mechanism of cellular adaption to inflammatory stress.
- Author
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Stachel I, Geismann C, Aden K, Deisinger F, Rosenstiel P, Schreiber S, Sebens S, Arlt A, and Schäfer H
- Subjects
- Animals, Apoptosis Regulatory Proteins genetics, Cell Line, Chromones pharmacology, Colitis chemically induced, Colitis genetics, Colon pathology, Dextran Sulfate toxicity, Enzyme Inhibitors pharmacology, Epithelial Cells pathology, Gene Expression Regulation drug effects, Gene Expression Regulation genetics, Humans, Immediate-Early Proteins genetics, Inflammation chemically induced, Inflammation genetics, Inflammation metabolism, Membrane Proteins genetics, Mice, Mice, Knockout, Morpholines pharmacology, NF-E2-Related Factor 2 genetics, Phosphatidylinositol 3-Kinases genetics, Phosphatidylinositol 3-Kinases metabolism, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Mas, Proto-Oncogene Proteins c-akt genetics, Proto-Oncogene Proteins c-akt metabolism, Proto-Oncogene Proteins c-fyn genetics, Proto-Oncogene Proteins c-fyn metabolism, Reactive Oxygen Species metabolism, Signal Transduction drug effects, Signal Transduction genetics, TNF-Related Apoptosis-Inducing Ligand genetics, TNF-Related Apoptosis-Inducing Ligand metabolism, Apoptosis Regulatory Proteins metabolism, Colitis metabolism, Colon metabolism, Epithelial Cells metabolism, Immediate-Early Proteins metabolism, Membrane Proteins metabolism, NF-E2-Related Factor 2 metabolism
- Abstract
Although nuclear factor E2-related factor-2 (Nrf2) protects from carcinogen-induced tumorigenesis, underlying the rationale for using Nrf2 inducers in chemoprevention, this antioxidative transcription factor may also act as a proto-oncogene. Thus, an enhanced Nrf2 activity promotes formation and chemoresistance of colon cancer. One mechanism causing persistent Nrf2 activation is the adaptation of epithelial cells to oxidative stress during chronic inflammation, e.g. colonocytes in inflammatory bowel diseases, and the multifunctional stress response gene immediate early response-3 (IER3) has a crucial role under these conditions. We now demonstrate that colonic tissue from Ier3(-/-) mice subject of dextran sodium sulfate colitis exhibit greater Nrf2 activity than Ier3(+/+) mice, manifesting as increased nuclear Nrf2 protein level and Nrf2 target gene expression. Likewise, human NCM460 colonocytes subjected to shRNA-mediated IER3 knockdown exhibit greater Nrf2 activity compared with control cells, whereas IER3 overexpression attenuated Nrf2 activation. IER3-deficient NCM460 cells exhibited reduced reactive oxygen species levels, indicating increased antioxidative protection, as well as lower sensitivity to TRAIL or anticancer drug-induced apoptosis and greater clonogenicity. Knockdown of Nrf2 expression reversed these IER3-dependent effects. Further, the enhancing effect of IER3 deficiency on Nrf2 activity relates to the control of the inhibitory tyrosine kinase Fyn by the PI3K/Akt pathway. Thus, the PI3K inhibitor LY294002 or knockdown of Akt or Fyn expression abrogated the impact of IER3 deficiency on Nrf2 activity. In conclusion, the interference of IER3 with the PI3K/Akt-Fyn pathway represents a novel mechanism of Nrf2 regulation that may get lost in tumors and by which IER3 exerts its stress-adaptive and tumor-suppressive activity.
- Published
- 2014
- Full Text
- View/download PDF
9. Biomimetically mineralized salmon collagen scaffolds for application in bone tissue engineering.
- Author
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Hoyer B, Bernhardt A, Heinemann S, Stachel I, Meyer M, and Gelinsky M
- Subjects
- Animals, Biomimetic Materials chemical synthesis, Bone Substitutes chemical synthesis, Cell Count, Cells, Cultured, Cross-Linking Reagents chemical synthesis, Cross-Linking Reagents chemistry, Humans, Mesenchymal Stem Cells cytology, Particle Size, Porosity, Salmon, Surface Properties, Biomimetic Materials chemistry, Bone Substitutes chemistry, Collagen chemistry, Tissue Engineering, Tissue Scaffolds chemistry
- Abstract
Biomimetic mineralization of collagen is an advantageous method to obtain resorbable collagen/hydroxy-apatite composites for application in bone regeneration. In this report, established procedures for mineralization of bovine collagen were adapted to a new promising source of collagen from salmon skin challenged by the low denaturation temperature. Therefore, in the first instance, variation of temperature, collagen concentration, and ionic strength was performed to reveal optimized parameters for fibrillation and simultaneous mineralization of salmon collagen. Porous scaffolds from mineralized salmon collagen were prepared by controlled freeze-drying and chemical cross-linking. FT-IR analysis demonstrated the mineral phase formed during the preparation process to be hydroxyapatite. The scaffolds exhibited interconnecting porosity, were sufficiently stable under cyclic compression, and showed elastic mechanical properties. Human mesenchymal stem cells were able to adhere to the scaffolds, cell number increased during cultivation, and osteogenic differentiation was demonstrated in terms of alkaline phosphatase activity.
- Published
- 2012
- Full Text
- View/download PDF
10. Cross-linking of type I collagen with microbial transglutaminase: identification of cross-linking sites.
- Author
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Stachel I, Schwarzenbolz U, Henle T, and Meyer M
- Subjects
- Chromatography, Gel, Electrophoresis, Polyacrylamide Gel, Spectrometry, Fluorescence, Bacteria enzymology, Collagen Type I metabolism, Transglutaminases metabolism
- Abstract
Collagen is a popular biomaterial. To deal with its lack of thermal stability and its weak resistance to proteolytic degradation, collagen-based materials are stabilized via different cross-linking procedures. Regarding the potential toxicity of residual cross-linking agents, enzyme-mediated cross-linking would provide an alternative and nontoxic method for collagen stabilization. The results of this study show that type I collagen is a substrate for mTG. However, epsilon-(gamma-glutamyl)lysine cross-links are only incorporated at elevated temperatures when the protein is partially or completely denatured. A maximum number of 5.4 cross-links per collagen monomer were found for heat-denatured collagen. Labeling with the primary amine monodansylcadaverine revealed that at least half of the cross-links are located within the triple helical region of the collagen molecule. Because the triple helix is highly ordered in its native state, this finding might explain why the glutamine residues are inaccessible for mTG under nondenaturing conditions.
- Published
- 2010
- Full Text
- View/download PDF
11. [Experiences with hydantal Sandoz and Mesantoin in the therapy of epilepsy of children].
- Author
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SCHMUTTERMEIER E and STACHEL I
- Subjects
- Child, Infant, Epilepsy, Hydantoins therapeutic use, Mephenytoin
- Published
- 1952
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