38 results on '"St Laurent Denis R"'
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2. HCV NS5A replication complex inhibitors. Part 3 : discovery of potent analogs with distinct core topologies
3. HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides
4. Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir
5. Discovery and Development of Hepatitis C Virus NS5A Replication Complex Inhibitors
6. Hepatitis C Virus NS5A Replication Complex Inhibitors. Part 6: Discovery of a Novel and Highly Potent Biarylimidazole Chemotype with Inhibitory Activity Toward Genotypes 1a and 1b Replicons
7. HCV NS5A Replication Complex Inhibitors. Part 4.1 Optimization for Genotype 1a Replicon Inhibitory Activity
8. Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes
9. ChemInform Abstract: Oxime Derivatives of Sordaricin as Potent Antifungal Agents.
10. Identification of Hepatitis C Virus NS5A Inhibitors
11. Ethynylp-Tolyl Sulfone
12. Novel 3‘,6‘-Anhydro and N12,N13-Bridged Glycosylated Fluoroindolo[2,3-a]carbazoles as Topoisomerase I Inhibitors. Fluorine as a Leaving Group from sp3Carbon
13. Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11
14. Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyranosyl]-5H,13H-benzo[b]thienyl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model.
15. Design and Synthesis of a Fluoroindolocarbazole Series as Selective Topoisomerase I Active Agents. Discovery of Water-Soluble 3,9-Difluoro-12,13-dihydro-13-[6-amino-β- d-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with Curative Antitumor Activity against Prostate Carcinoma Xenograft Tumor Model
16. Regioselective synthesis of 3-(heteroaryl)-iminothiazolidin-4-ones
17. Sordarin Oxazepine Derivatives as Potent Antifungal Agents
18. ChemInform Abstract: Mild Deprotection of 2‐(Trimethylsilyl)ethyl Esters.
19. Oxime derivatives of sordaricin as potent antifungal agents
20. Mild deprotection of 2-(trimethylsilyl)ethyl esters
21. Ethynylp-Tolyl Sulfone
22. Ethyl β-Phenylsulfonylpropiolate
23. HCV NS5AReplication Complex Inhibitors. Part 4.1 Optimization for Genotype 1a Replicon InhibitoryActivity.
24. Discovery and Developmentof Hepatitis C Virus NS5AReplication Complex Inhibitors.
25. Hepatitis C Virus NS5A ReplicationComplex Inhibitors.Part 6: Discovery of a Novel and Highly Potent Biarylimidazole Chemotypewith Inhibitory Activity Toward Genotypes 1a and 1b Replicons.
26. Effect of a novel thrombin active-site inhibitor on arterial and venous thrombosis
27. Total synthesis of the Lycopodium alkaloids magellanine and magellaninone by three-fold...
28. Hepatitis C Virus Inhibitors
29. Hepatitis C Virus Inhibitors
30. Hepatitis C Virus Inhibitors
31. Hepatitis C Virus Inhibitors
32. Hepatitis C Virus Inhibitors
33. Hepatitis C Virus Inhibitors
34. Hepatitis C Virus Inhibitors
35. Cyclopentannulation with a 1,3-dicarbonyl dipole equivalent. Synthesis of bicyclo[3.3.0]oct-1(5)-ene-2,6-dione
36. ChemInform Abstract: Oxime Derivatives of Sordaricin as Potent Antifungal Agents.
37. HCV NS5A replication complex inhibitors. Part 31: discovery of potent analogs with distinct core topologies
38. Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model.
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