28 results on '"Stöcker, Andreas"'
Search Results
2. Propidium Monoazide Real-Time Quantitative Polymerase Chain Reaction for Sulfate Reducing Bacteria Viability Assay
- Author
-
Sampaio, Igor Carvalho Fontes, primary, Matos, Josilene Borges Torres Lima, additional, Chinalia, Fabio Alexandre, additional, Stöcker, Andreas, additional, and de Almeida, Paulo Fernando, additional
- Published
- 2023
- Full Text
- View/download PDF
3. A novel hepatitis B virus species discovered in capuchin monkeys sheds new light on the evolution of primate hepadnaviruses
- Author
-
de Carvalho Dominguez Souza, Breno Frederico, König, Alexander, Rasche, Andrea, de Oliveira Carneiro, Ianei, Stephan, Nora, Corman, Victor Max, Roppert, Pia Luise, Goldmann, Nora, Kepper, Ramona, Müller, Simon Franz, Völker, Christof, de Souza, Alex Junior Souza, Gomes-Gouvêa, Michele Soares, Moreira-Soto, Andrés, Stöcker, Andreas, Nassal, Michael, Franke, Carlos Roberto, Rebello Pinho, João Renato, Soares, Manoel do Carmo Pereira, Geyer, Joachim, Lemey, Philippe, Drosten, Christian, Netto, Eduardo Martins, Glebe, Dieter, and Drexler, Jan Felix
- Published
- 2018
- Full Text
- View/download PDF
4. Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes
- Author
-
Drexler, Jan Felix, Geipel, Andreas, König, Alexander, Corman, Victor M., van Riel, Debby, Leijten, Lonneke M., Bremer, Corinna M., Rasche, Andrea, Cottontail, Veronika M., Magangaf, Gael D., Schlegel, Mathias, Müller, Marcel A., Adam, Alexander, Klose, Stefan M., Carneiro, Aroldo José Borges, Stöcker, Andreas, Franke, Carlos Roberto, Rausch, Florian Gloza, Geyer, Joachim, Annan, Augustina, Adu-Sarkodie, Yaw, Oppongn, Samuel, Binger, Tabea, Vallo, Peter, Tschapka, Marco, Ulrich, Rainer G., Gerlich, Wolfram H., Leroy, Eric, Kuiken, Thijs, Glebe, Dieter, and Drosten, Christian
- Published
- 2013
5. Microbiological findings of the maternal periodontitis associated to low birthweight
- Author
-
Oliveira, Mariana Cedraz de, primary, Gomes-Filho, Isaac Suzart, additional, Stöcker, Andreas, additional, Barreto, Laerte Oliveira, additional, Santos, André do Nascimento, additional, Cruz, Simone Seixas da, additional, Passos-Soares, Johelle Santana, additional, Falcão, Michelle Miranda Lopes, additional, Meireles, José Roberto Cardoso, additional, Seymour, Gregory John, additional, Meyer, Roberto, additional, and Trindade, Soraya Castro, additional
- Published
- 2020
- Full Text
- View/download PDF
6. Prevotella intermedia and periodontitis are associated with severe asthma
- Author
-
Lopes, Mabel P., primary, Cruz, Álvaro A., additional, Xavier, Márcia T., additional, Stöcker, Andreas, additional, Carvalho‐Filho, Paulo, additional, Miranda, Patrícia M., additional, Meyer, Roberto J., additional, Soledade, Kaliane R., additional, Gomes‐Filho, Isaac S., additional, and Trindade, Soraya C., additional
- Published
- 2019
- Full Text
- View/download PDF
7. Prevotella intermedia and periodontitis are associated with severe asthma.
- Author
-
Lopes, Mabel P., Cruz, Álvaro A., Xavier, Márcia T., Stöcker, Andreas, Carvalho‐Filho, Paulo, Miranda, Patrícia M., Meyer, Roberto J., Soledade, Kaliane R., Gomes‐Filho, Isaac S., Trindade, Soraya C., Carvalho-Filho, Paulo, and Gomes-Filho, Isaac S
- Abstract
Background: Periodontitis, an inflammatory disease of multibacterial etiology that affects the protective and supporting tissues surrounding teeth, can influence the course of respiratory diseases, such as asthma, due to epithelial alterations arising from inflammatory and immunological processes, bronchial remodeling, or by the aspiration of pathogenic colonizers found in periodontal pockets. This study evaluated the levels of periodontal pathogens Prevotella intermedia, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans in the subgingival biofilm of individuals with and without severe asthma.Methods: A case-control study enrolling 457 individuals (220 with asthma and 237 without asthma) was conducted at the Program for Control of Asthma in Bahia (ProAR) Clinic located in Salvador, Bahia, Brazil. A structured questionnaire was used to obtain data on sociodemographic, health status, and lifestyle habits. A clinical periodontal assessment was performed, including bleeding on probing, probing depth, and clinical attachment level. Subgingival biofilm was collected at the deepest site of each sextant, and bacterial DNA was extracted. Quantitative real-time PCR analysis was performed to detect and relatively quantify periodontopathogens in the biofilm.Results: Statistically significant positive associations were found between periodontitis and severe asthma, (odds ratio [OR]adjusted] : 4.00; 95% confidence interval [CI]: 2.26 to 7.10). High levels of P. intermedia were found in association with the presence of severe asthma (ORadjusted : 2.64; 95% CI: 1.62 to 4.39; P < 0.01).Conclusions: The present results suggest that periodontitis and P. intermedia are associated with severe asthma. However, the functional consequences of this dysbiosis upon asthma susceptibility and its phenotypes remain unclear. [ABSTRACT FROM AUTHOR]- Published
- 2020
- Full Text
- View/download PDF
8. Prototypische Integration automatisierter Programmbewertung in das LMS Moodle
- Author
-
Becker, Sebastian, Stöcker, Andreas, Bräckelmann, Daniel, Garmann, Robert, Grzanna, Sören, Heine, Felix, Kleiner, Carsten, Werner, Peter, and Bott, Oliver J.
- Subjects
ddc:004 ,004 Informatik - Abstract
Der Beitrag erläutert die prototypische Integration automatisierter Programmbewertung in das LMS Moodle.Beschrieben wird die Grader-unabhängige Schnittstelle Grappa und die Moodle-Integration.
- Published
- 2016
- Full Text
- View/download PDF
9. Lerntrainings als Antwort der Schule auf defizitäre häusliche Unterstützung? Analysen zum Kompensationspotenzial schulischer Lerntrainings am Beispiel des Konzepts der Realschule Enger
- Author
-
Huber-Stöcker, Andreas
- Subjects
Kompensation ,Selbstgesteuertes Lernen ,Motivation ,ddc:370 ,Selbstwirksamkeit ,Lerntraining - Abstract
Dass Eltern positiven, negativen oder ausbleibenden Einfluss auf das Lernverhalten nehmen können, ist gesichert. Ebenso ist die diesbezügliche Wirkung von Methoden- bzw. Lerntrainings nachgewiesen. Bislang wurden beide Entwicklungsfaktoren noch nicht miteinander in Beziehung gesetzt. Die hier gegenständliche Studie geht am Beispiel des Lerntrainings der Realschule Enger der Frage nach, ob ein schulisches Lerntraining dazu in der Lage ist, defizitäre häusliche Unterstützung auszugleichen. Fernerhin interessieren sich hieraus ergebende Anforderungen, welche an die Konzeption eines Lerntrainings - insbesondere unter kompensatorischen Intentionen - zu stellen sind. Dazu werden in den Jahrgangsstufen 5 bis 9 Extremgruppen (Kontrollgruppe = funktionale elterliche Unterstützung durch die Eltern, kein Lerntraining; Aktionsgruppe = dysfunktionale elterliche Unterstützung, Teilnahme am Lerntraining) gebildet und in der Funktionalitätsstruktur des Lernverhaltens (konzeptspezifiert nach dem Drei-Schalen-Modell nach Boekaerts) verglichen. Zentrales Ergebnis ist, dass das exemplarische Lerntraining defizitäre häusliche Unterstützung nicht vollständig, aber stark auszugleichen vermag, was einer dauerhaften motivationalen Benachteiligung der Aktionsgruppe geschuldet ist. Weiterhin zeigen sich Kompensationseffekte des Trainings auf das Elternverhalten. Die Selbstregulation bildet für häuslich ungünstig Unterstützte ein zentrales Problem.
- Published
- 2015
10. Prevotella intermediaand periodontitis are associated with severe asthma
- Author
-
Lopes, Mabel P., Cruz, Álvaro A., Xavier, Márcia T., Stöcker, Andreas, Carvalho‐Filho, Paulo, Miranda, Patrícia M., Meyer, Roberto J., Soledade, Kaliane R., Gomes‐Filho, Isaac S., and Trindade, Soraya C.
- Abstract
Periodontitis, an inflammatory disease of multibacterial etiology that affects the protective and supporting tissues surrounding teeth, can influence the course of respiratory diseases, such as asthma, due to epithelial alterations arising from inflammatory and immunological processes, bronchial remodeling, or by the aspiration of pathogenic colonizers found in periodontal pockets. This study evaluated the levels of periodontal pathogens Prevotella intermedia, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, and Aggregatibacter actinomycetemcomitansin the subgingival biofilm of individuals with and without severe asthma. A case‐control study enrolling 457 individuals (220 with asthma and 237 without asthma) was conducted at the Program for Control of Asthma in Bahia (ProAR) Clinic located in Salvador, Bahia, Brazil. A structured questionnaire was used to obtain data on sociodemographic, health status, and lifestyle habits. A clinical periodontal assessment was performed, including bleeding on probing, probing depth, and clinical attachment level. Subgingival biofilm was collected at the deepest site of each sextant, and bacterial DNA was extracted. Quantitative real‐time PCR analysis was performed to detect and relatively quantify periodontopathogens in the biofilm. Statistically significant positive associations were found between periodontitis and severe asthma, (odds ratio [OR]adjusted]: 4.00; 95% confidence interval [CI]: 2.26 to 7.10). High levels of P. intermediawere found in association with the presence of severe asthma (ORadjusted: 2.64; 95% CI: 1.62 to 4.39; P< 0.01). The present results suggest that periodontitis and P. intermediaare associated with severe asthma. However, the functional consequences of this dysbiosis upon asthma susceptibility and its phenotypes remain unclear.
- Published
- 2020
- Full Text
- View/download PDF
11. Envolvimento do Desmodus rotundus no ciclo epidemiológico das leishmanioses na Bahia, Brasil
- Author
-
Cunha, Rogério de Magalhães, Carneiro, Aroldo José Borges, Gonçalves, Rafaela de Sousa, Becerra, Dinah Ribeiro Dantas, Stöcker, Andreas, Barrouin-Melo, Stella Maria, and Franke, Carlos Roberto
- Subjects
Leishmania ,zoonose ,PCR ,parasitic diseases ,wild animals ,bat ,zoonosis ,morcegos ,quirópteros - Abstract
As leishmanioses são protozoonoses causadas por diferentes espécies do gênero Leishmania. Pouco se sabe sobre o papel de algumas espécies de mamíferos na epidemiologia dessas doenças. Alguns relatos apontam quirópteros como potenciais hospedeiros. Este estudo visa avaliar a presença de infecção por Leishmania spp. em Desmodus rotundus. Métodos moleculares capazes de identificar fragmentos de DNA de Leishmania foram empregados para as análises dos 100 quirópteros envolvidos neste estudo . Em 16% das amostras foram detectados presença de DNA de Leishmania sp. com a PCR (Polymerase Chain Reaction) convencional. Contudo, tal resultado não se repetiu quando avaliadas pela PCR em Tempo Real, aplicada com finalidade de distinção das espécies de Leishmania, o que sugeriu a ocorrência de contaminação das amostras na análise prévia. Apesar deste resultado, aspectos comportamentais e da biologia do D. rotundus sugerem que eles, assim como outras espécies de quirópteros, sejam potenciais hospedeiros destes protozoários. Leishmaniasis are protozoonosis caused by different Leishmania species. The role of some wild mammal's species in the epidemiology of these diseases is not well known. A few studies point to chiropteran as possible hosts. The aim of this study was to evaluate the presence of Leishmania spp. infection in Desmodus rotundus (vampire bat). Molecular methods capable of amplifying the DNA of Leishmania were used to evaluate one hundred chiropters from this species. In 16% of the samples, the DNA of Leishmania sp. was detected through PCR (Polymerase Chain Reaction), in the trial stage. However, the result was not repeated when evaluated through Real Time PCR, which suggested the occurrence of prior sample contamination. In spite of this result, some behavioral and biological aspects of D. rotundus suggest that they, in a similar vein to other bat species, are potential hosts for these protozoans.
- Published
- 2014
12. Corrigendum: Bats host major mammalian paramyxoviruses
- Author
-
Drexler, Jan Felix, Corman, Victor Max, Müller, Marcel Alexander, Maganga, Gael Darren, Vallo, Peter, Binger, Tabea, Gloza-Rausch, Florian, Cottontail, Veronika M., Rasche, Andrea, Yordanov, Stoian, Seebens, Antje, Knörnschild, Mirjam, Oppong, Samuel, Sarkodie, Yaw Adu, Pongombo, Célestin, Lukashev, Alexander N., Schmidt-Chanasit, Jonas, Stöcker, Andreas, Carneiro, Aroldo José Borges, Erbar, Stephanie, Maisner, Andrea, Fronhoffs, Florian, Buettner, Reinhard, Kalko, Elisabeth K. V., Kruppa, Thomas, Franke, Carlos Roberto, Kallies, René, Yandoko, Emmanuel R. N., Herrler, Georg, Reusken, Chantal, Hassanin, Alexandre, Krüger, Detlev H., Matthee, Sonja, Ulrich, Rainer G., Leroy, Eric M., and Drosten, Christian
- Subjects
Corrigenda - Published
- 2014
13. Journal of Periodontology
- Author
-
Trindade, Soraya Castro, Olczak, Teresa, Gomes Filho, Isaac Suzart, Costa, Lília Ferreira de Moura, Vale, Vera Costa, Galdino Neto, Milton, Santos, Heidiane Alves dos, Carvalho Filho, Paulo Cirino de, Stöcker, Andreas, Bendicho, Maria Teresita Del Niño Jesus Fernandez, Xavier, Márcia Tosta, Cerqueira, Eneida de Moraes Marcílio, and Nascimento, Roberto José Meyer
- Subjects
Interleukin-6 ,Periodontitis ,Porphyromonas gingivalis - Abstract
Acesso restrito: p. 650-655 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-12-16T11:21:11Z No. of bitstreams: 1 Soraya Castro Trindade.pdf: 510609 bytes, checksum: c5168586f5b6da648adc8ecb8d5ad214 (MD5) Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2015-01-09T13:29:09Z (GMT) No. of bitstreams: 1 Soraya Castro Trindade.pdf: 510609 bytes, checksum: c5168586f5b6da648adc8ecb8d5ad214 (MD5) Made available in DSpace on 2015-01-09T13:29:09Z (GMT). No. of bitstreams: 1 Soraya Castro Trindade.pdf: 510609 bytes, checksum: c5168586f5b6da648adc8ecb8d5ad214 (MD5) Previous issue date: 2013 Background: In chronic periodontitis (CP), the gene polymorphism of interleukin-6 (IL-6) to 174C/G has been associated with the altered production of this cytokine. The aim of this pilot study is to compare the allelic and genotypic frequencies in patients with CP with control individuals without periodontitis (NP) and to measure the production of IL-6 by whole blood cells stimulated with Porphyromonas gingivalis HmuY protein. Methods: DNA was isolated from peripheral blood cells of 49 patients with CP and 60 control individuals classified as NP, and genotyping was performed by polymerase chain reaction using sequence-specific primers. Whole blood cells from 29 patients with CP and 30 control individuals were stimulated for 48 hours with HmuY, and IL-6 levels were measured using enzyme-linked immunosorbent assay. Results: The proportion of individuals carrying the G allele at position –174 of the IL-6 gene was higher in the group with CP (85.7%) than in the normal control group (73.3%; P
- Published
- 2013
- Full Text
- View/download PDF
14. Emerging Infectious Diseases
- Author
-
Stöcker, Andreas, Souza, Breno Frederico de Carvalho Dominguez, Ribeiro, Tereza Cristina Medrado, Martins Netto, Eduardo, Araujo, Luciana Oliveira, Corrêa, Jefferson Ivan, Almeida, Patrícia Silva, and Mattos, Angela Peixoto de
- Abstract
p. 656-659 Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-08-18T12:14:42Z No. of bitstreams: 1 Andreas Stöcker.pdf: 335325 bytes, checksum: 87d2af6acbe162b996217a1697fd6fa8 (MD5) Approved for entry into archive by Delba Rosa (delba@ufba.br) on 2014-09-29T13:42:22Z (GMT) No. of bitstreams: 1 Andreas Stöcker.pdf: 335325 bytes, checksum: 87d2af6acbe162b996217a1697fd6fa8 (MD5) Made available in DSpace on 2014-09-29T13:42:22Z (GMT). No. of bitstreams: 1 Andreas Stöcker.pdf: 335325 bytes, checksum: 87d2af6acbe162b996217a1697fd6fa8 (MD5) Previous issue date: 2012 To determine possible cosavirus association with clinical disease, we used real-time reverse transcription PCR to test children and HIV-positive adults in Brazil with and without gastroenteritis. Thirteen (3.6%) of 359 children with gastroenteritis tested positive, as did 69 (33.8%) of 204 controls. Low prevalence, frequent viral co-infections, and low fecal cosavirus RNA concentrations argue against human pathogenicity.
- Published
- 2012
- Full Text
- View/download PDF
15. Journal of General Virology
- Author
-
Drexler, Jan Felix, Baumgarte, Sigrid, Luna, Luciano Kleber de Souza, Stöcker, Andreas, Almeida, Patrícia Silva, Ribeiro, Tereza Cristina Medrado, Pedroso, Célia, Brites, Carlos, and Ribeiro Jr, Hugo da Costa
- Abstract
Texto completo: acesso restrito. p.1418-1427 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-08-28T14:52:47Z No. of bitstreams: 1 Jan Drexler1418.full.pdf: 563463 bytes, checksum: 23a2f23905662e9ee3ad6769391d0b2d (MD5) Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-10-31T18:07:25Z (GMT) No. of bitstreams: 1 Jan Drexler1418.full.pdf: 563463 bytes, checksum: 23a2f23905662e9ee3ad6769391d0b2d (MD5) Made available in DSpace on 2013-10-31T18:07:25Z (GMT). No. of bitstreams: 1 Jan Drexler1418.full.pdf: 563463 bytes, checksum: 23a2f23905662e9ee3ad6769391d0b2d (MD5) Previous issue date: 2010 This study identified the complete genomic sequence of four type 2 and type 3 human Saffold-like cardioviruses (SLCVs) isolated in Germany and Brazil. The secondary structures of the SLCV internal ribosome entry sites (IRESs) were deduced based on RNA base-pairing conservation and co-variation, using an established Theiler's murine encephalomyelitis virus (TMEV) IRES structure as a reference. The SLCV IRES was highly similar to that of TMEV, but motifs critical in TMEV for binding of the polypyrimidine tract-binding protein (PTB) were disrupted. In TMEV, corresponding alterations have been associated with reduced neurovirulence in mice. In the non-structural genome region, there was evidence of multiple intertypic recombination events between different SLCV types. Between viruses of the same type, recombination also occurred in the capsid-encoding genome region. There were apparently no recombination events between mouse TMEV and human SLCV. In another genus of the family Picornaviridae, Enterovirus, natural recombination occurs strictly within species and can serve as an additional criterion for delimiting species. Accordingly, the results of this study suggest that SLCV and TMEV may represent distinct species within the genus Cardiovirus.
- Published
- 2010
- Full Text
- View/download PDF
16. Emerging Infectious Diseases
- Author
-
Drexler, Jan Felix, Grywna, Klaus, Stöcker, Andreas, Almeida, Patrícia Silva, Ribeiro, Tereza Cristina Medrado, Eschbach Bludau, Monika, Petersen, Nadine, Ribeiro, Hugo da Costa, and Drosten, Christian
- Abstract
p. 310-313 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-11-01T14:46:24Z No. of bitstreams: 1 08-1028.pdf: 444128 bytes, checksum: 90b61e82d1529ce104156ef5dcd42d7c (MD5) Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-08T18:28:33Z (GMT) No. of bitstreams: 1 08-1028.pdf: 444128 bytes, checksum: 90b61e82d1529ce104156ef5dcd42d7c (MD5) Made available in DSpace on 2013-11-08T18:28:33Z (GMT). No. of bitstreams: 1 08-1028.pdf: 444128 bytes, checksum: 90b61e82d1529ce104156ef5dcd42d7c (MD5) Previous issue date: 2009 Human parechoviruses (HPeVs) were detected by reverse transcription–PCR in 16.1% of 335 stool samples from children
- Published
- 2009
- Full Text
- View/download PDF
17. Emerging Infectious Diseases
- Author
-
Drexler, Jan Felix, Luna, Luciano Kleber de Souza, Stöcker, Andreas, Almeida, Patrícia Silva, Ribeiro, Tereza Cristina Medrado, Pedroso, Célia, and Ribeiro, Hugo da Costa
- Abstract
p. 1398-1405 Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-11-26T12:26:55Z No. of bitstreams: 1 10.3201eid1409.080570.pdf: 257095 bytes, checksum: 07bdb0bfc4640ec20260e7bbfa35dcf9 (MD5) Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-26T12:55:15Z (GMT) No. of bitstreams: 1 10.3201eid1409.080570.pdf: 257095 bytes, checksum: 07bdb0bfc4640ec20260e7bbfa35dcf9 (MD5) Made available in DSpace on 2013-11-26T12:55:15Z (GMT). No. of bitstreams: 1 10.3201eid1409.080570.pdf: 257095 bytes, checksum: 07bdb0bfc4640ec20260e7bbfa35dcf9 (MD5) Previous issue date: 2008 Cardioviruses cause serious disease, mainly in rodents, including diabetes, myocarditis, encephalomyelitis, and multiple sclerosis–like disseminated encephalomyelitis. Recently, a human virus isolate obtained 25 years ago, termed Saffold virus, was sequenced and classified as a cardiovirus. We conducted systematic molecular screening for Saffold-like viruses in 844 fecal samples from patients with gastroenteritis from Germany and Brazil, across all age groups. Six cardioviruses were identified in patients
- Published
- 2008
- Full Text
- View/download PDF
18. Envolvimento do Desmodus rotundus no ciclo epidemiológico das leishmanioses na Bahia, Brasil
- Author
-
Cunha, Rogério de Magalhães, primary, Carneiro, Aroldo José Borges, additional, Gonçalves, Rafaela de Sousa, additional, Becerra, Dinah Ribeiro Dantas, additional, Stöcker, Andreas, additional, Barrouin-Melo, Stella Maria, additional, and Franke, Carlos Roberto, additional
- Published
- 2014
- Full Text
- View/download PDF
19. Correction: Corrigendum: Bats host major mammalian paramyxoviruses
- Author
-
Drexler, Jan Felix, primary, Corman, Victor Max, additional, Müller, Marcel Alexander, additional, Maganga, Gael Darren, additional, Vallo, Peter, additional, Binger, Tabea, additional, Gloza-Rausch, Florian, additional, Cottontail, Veronika M., additional, Rasche, Andrea, additional, Yordanov, Stoian, additional, Seebens, Antje, additional, Knörnschild, Mirjam, additional, Oppong, Samuel, additional, Sarkodie, Yaw Adu, additional, Pongombo, Célestin, additional, Lukashev, Alexander N., additional, Schmidt-Chanasit, Jonas, additional, Stöcker, Andreas, additional, Carneiro, Aroldo José Borges, additional, Erbar, Stephanie, additional, Maisner, Andrea, additional, Fronhoffs, Florian, additional, Buettner, Reinhard, additional, Kalko, Elisabeth K. V., additional, Kruppa, Thomas, additional, Franke, Carlos Roberto, additional, Kallies, René, additional, Yandoko, Emmanuel R. N., additional, Herrler, Georg, additional, Reusken, Chantal, additional, Hassanin, Alexandre, additional, Krüger, Detlev H., additional, Matthee, Sonja, additional, Ulrich, Rainer G., additional, Leroy, Eric M., additional, and Drosten, Christian, additional
- Published
- 2014
- Full Text
- View/download PDF
20. Highly diversified coronaviruses in neotropical bats
- Author
-
Corman, Victor Max, primary, Rasche, Andrea, additional, Diallo, Thierno Diawo, additional, Cottontail, Veronika M., additional, Stöcker, Andreas, additional, Souza, Breno Frederico de Carvalho Dominguez, additional, Corrêa, Jefferson Ivan, additional, Carneiro, Aroldo José Borges, additional, Franke, Carlos Roberto, additional, Nagy, Martina, additional, Metz, Markus, additional, Knörnschild, Mirjam, additional, Kalko, Elisabeth K. V., additional, Ghanem, Simon J., additional, Morales, Karen D. Sibaja, additional, Salsamendi, Egoitz, additional, Spínola, Manuel, additional, Herrler, Georg, additional, Voigt, Christian C., additional, Tschapka, Marco, additional, Drosten, Christian, additional, and Drexler, Jan Felix, additional
- Published
- 2013
- Full Text
- View/download PDF
21. Bats host major mammalian paramyxoviruses
- Author
-
Drexler, Jan Felix, primary, Corman, Victor Max, additional, Müller, Marcel Alexander, additional, Maganga, Gael Darren, additional, Vallo, Peter, additional, Binger, Tabea, additional, Gloza-Rausch, Florian, additional, Cottontail, Veronika M., additional, Rasche, Andrea, additional, Yordanov, Stoian, additional, Seebens, Antje, additional, Knörnschild, Mirjam, additional, Oppong, Samuel, additional, Sarkodie, Yaw Adu, additional, Pongombo, Célestin, additional, Lukashev, Alexander N., additional, Schmidt-Chanasit, Jonas, additional, Stöcker, Andreas, additional, Carneiro, Aroldo José Borges, additional, Erbar, Stephanie, additional, Maisner, Andrea, additional, Fronhoffs, Florian, additional, Buettner, Reinhard, additional, Kalko, Elisabeth K. V., additional, Kruppa, Thomas, additional, Franke, Carlos Roberto, additional, Kallies, René, additional, Yandoko, Emmanuel R.N., additional, Herrler, Georg, additional, Reusken, Chantal, additional, Hassanin, Alexandre, additional, Krüger, Detlev H., additional, Matthee, Sonja, additional, Ulrich, Rainer G., additional, Leroy, Eric M., additional, and Drosten, Christian, additional
- Published
- 2012
- Full Text
- View/download PDF
22. Cosavirus Infection in Persons with and without Gastroenteritis, Brazil
- Author
-
Stöcker, Andreas, primary, de Carvalho Dominguez Souza, Breno Frederico, additional, Ribeiro, Tereza Cristina Medrado, additional, Netto, Eduardo Martins, additional, Araujo, Luciana Oliveira, additional, Corrêa, Jefferson Ivan, additional, Almeida, Patrícia Silva, additional, Peixoto de Mattos, Angela, additional, Ribeiro, Hugo da Costa, additional, Pedral-Sampaio, Diana Brasil, additional, Drosten, Christian, additional, and Drexler, Jan Felix, additional
- Published
- 2012
- Full Text
- View/download PDF
23. Rabies Virus RNA in Naturally Infected Vampire Bats, Northeastern Brazil
- Author
-
Carneiro, Aroldo J.B., primary, Franke, Carlos R., additional, Stöcker, Andreas, additional, dos Santos, Flávia, additional, Úngar de Sá, José E., additional, Moraes-Silva, Evandro, additional, Alves, José N.M., additional, Brünink, Sebastian, additional, Corman, Victor M., additional, Drosten, Christian, additional, and Drexler, Jan F., additional
- Published
- 2010
- Full Text
- View/download PDF
24. Novel Human Parechovirus from Brazil
- Author
-
Drexler, Jan Felix, primary, Grywna, Klaus, additional, Stöcker, Andreas, additional, Almeida, Patrícia Silva, additional, Ribeiro, Tereza Cristina Medrado, additional, Eschbach-Bludau, Monika, additional, Petersen, Nadine, additional, Ribeiro, Hugo da Costa, additional, and Drosten, Christian, additional
- Published
- 2009
- Full Text
- View/download PDF
25. Circulation of 3 Lineages of a Novel Saffold Cardiovirus in Humans
- Author
-
Drexler, Jan Felix, primary, Luna, Luciano Kleber de Souza, additional, Stöcker, Andreas, additional, Almeida, Patrícia Silva, additional, Ribeiro, Tereza Cristina Medrado, additional, Petersen, Nadine, additional, Herzog, Petra, additional, Pedroso, Célia, additional, Huppertz, Hans Iko, additional, Ribeiro, Hugo da Costa, additional, Baumgarte, Sigrid, additional, and Drosten, Christian, additional
- Published
- 2008
- Full Text
- View/download PDF
26. Microbiological findings of the maternal periodontitis associated to low birthweight.
- Author
-
Cedraz de Oliveira, Mariana, Suzart Gomes-Filho, Isaac, Stöcker, Andreas, Oliveira Barreto Neto, Laerte, do Nascimento Santos, André, Seixas da Cruz, Simone, Santana Passos-Soares, Johelle, Miranda Lopes Falcão, Michelle, Cardoso Meireles, José Roberto, Seymour, Gregory John, Meyer, Roberto, and Castro Trindade, Soraya
- Subjects
- *
PERIODONTITIS , *MATERNAL health , *LOW birth weight , *BIOFILMS , *PORPHYROMONAS - Abstract
Objective: To determine the association between the presence of periodontal pathogens and low birthweight. Methods: This observational and case-control study consisted of mothers of infants weighing <2,500g (Group A), and mothers of newborns weighing ≥2,500g (Group B), born at Hospital da Mulher in Feira de Santana (BA), Brazil. A semi-structured questionnaire covering demographic data, gestational history and aspects related to general and oral health was employed postpartum. Following a complete periodontal examination, biofilm samples were collected at six sites in the mouth. The participants were further categorized in terms of presence or absence of periodontitis. Differences between the groups were determined using Pearson's χ² test, odds ratio, and confidence intervals were obtained using the Mantel-Haenszel test. Results: Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia and Prevotella intermedia were detected by polymerase chain reaction. A total of 303 postpartum women were evaluated, 224 (73.9%) in Group B. Statistically significant differences between the groups were found for age, body mass index and history of previous low birthweight babies. Group A had a higher frequency of periodontitis (33.34%) than Group B (16.22%). P. gingivalis and P. intermedia were detected more frequently among women with periodontitis (74.19% and 88.70%, respectively). Conclusion: In this population, there was no association between the presence of maternal periodontal pathogens and the occurrence of low birthweight infants. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
27. Full genome sequence analysis of parechoviruses from Brazil reveals geographical patterns in the evolution of non-structural genes and intratypic recombination in the capsid region.
- Author
-
Drexler JF, Grywna K, Lukashev A, Stöcker A, Almeida PS, Wieseler J, Ribeiro TC, Petersen N, Ribeiro Hda C Jr, Belalov I, Kümmerer BM, and Drosten C
- Subjects
- Brazil, Capsid Proteins genetics, Cluster Analysis, Humans, Molecular Sequence Data, Parechovirus classification, Phylogeny, RNA, Viral genetics, Sequence Analysis, DNA, Sequence Homology, Viral Nonstructural Proteins genetics, Evolution, Molecular, Genome, Viral, Parechovirus genetics, Parechovirus isolation & purification, Picornaviridae Infections virology, Recombination, Genetic
- Abstract
Due to high genome plasticity, the evolutionary fate and geographical history of picornaviruses is hard to follow. Here, we determined the complete coding sequences of eight human parechoviruses (HPeV) of types 1, 5 and 6 directly from clinical samples from Brazil. The capsid genes of these strains were not remarkably different from European, North American and Japanese HPeV. Full genome analysis revealed frequent intertypic recombination in the non-structural genome region. In addition, evidence of recombination between viruses of the same type in the capsid-encoding genome region among HPeV1 and HPeV4 was obtained. Bayesian phylogenetic analysis indicated that strains without evidence of recombination with each other in any genome region were separated by no more than 35 years of circulation. Interestingly, in the 3C gene, all Brazilian parechoviruses grouped together regardless of serotype. The most recent common ancestor of these strains dated back 108 years, suggesting long-term endemicity of this particular P3 genome lineage in South America. Our results support the idea that picornavirus replicative genes acquire capsid proteins introduced by new strains. Under certain epidemiological conditions, replicative genes may be maintained in circumscript geographical regions.
- Published
- 2011
- Full Text
- View/download PDF
28. Genomic features and evolutionary constraints in Saffold-like cardioviruses.
- Author
-
Drexler JF, Baumgarte S, Luna LK, Stöcker A, Almeida PS, Ribeiro TC, Petersen N, Herzog P, Pedroso C, Brites C, Ribeiro Hda C Jr, Gmyl A, Drosten C, and Lukashev A
- Subjects
- Animals, Brazil, Cardiovirus classification, Cardiovirus isolation & purification, Cardiovirus Infections virology, Germany, Humans, Mice, Molecular Sequence Data, Nucleic Acid Conformation, Recombination, Genetic, Theilovirus genetics, Viral Nonstructural Proteins genetics, Viral Structural Proteins genetics, Cardiovirus genetics, Evolution, Molecular, Genome, Viral, RNA, Viral genetics, Sequence Analysis, DNA
- Abstract
This study identified the complete genomic sequence of four type 2 and type 3 human Saffold-like cardioviruses (SLCVs) isolated in Germany and Brazil. The secondary structures of the SLCV internal ribosome entry sites (IRESs) were deduced based on RNA base-pairing conservation and co-variation, using an established Theiler's murine encephalomyelitis virus (TMEV) IRES structure as a reference. The SLCV IRES was highly similar to that of TMEV, but motifs critical in TMEV for binding of the polypyrimidine tract-binding protein (PTB) were disrupted. In TMEV, corresponding alterations have been associated with reduced neurovirulence in mice. In the non-structural genome region, there was evidence of multiple intertypic recombination events between different SLCV types. Between viruses of the same type, recombination also occurred in the capsid-encoding genome region. There were apparently no recombination events between mouse TMEV and human SLCV. In another genus of the family Picornaviridae, Enterovirus, natural recombination occurs strictly within species and can serve as an additional criterion for delimiting species. Accordingly, the results of this study suggest that SLCV and TMEV may represent distinct species within the genus Cardiovirus.
- Published
- 2010
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.