Search

A new equation of state (NEOS) for Halides has been developed using the theory of lattice potential and the concept of volume dependence of the short-range force constant. The derivation of this equation of state involved the use of the third-order approximation of the lattice potential. A comparative analysis was conducted between the isothermal equations of state, including Vinet EOS, Murnaghan EOS, Holzapfel EOS, Born-Mie EOS, Birch-Murnaghan EOS, and the newly derived NEOS. The NEOS was used to analyze the compression behavior of Halides, and it was found that Vinet EOS and NEOS agreed with the experimental data for Halides up to high compression. However, Murnaghan EOS, Born-Mie EOS, Holzapfel EOS, and Birch-Murnaghan EOS are usually less sensitive to calculating pressure at high compression. It was also observed that for some Halides, such as NaBr and NaI, Vinet EOS could not produce results consistent with experimental findings. In contrast, NEOS consistently produced results that matched the experimental findings for all Halides samples, unequivocally demonstrating its reliability and accuracy. [ABSTRACT FROM AUTHOR]

The manipulation of spin textures by spin currents is of fundamental and technological interest. A particularly interesting system is the 2D van der Waals ferromagnet Fe3GeTe2, in which Néel-type skyrmions have recently been observed. The origin of these chiral spin textures is of considerable interest. Recently, it was proposed that these derive from defects in the structure that lower the symmetry and allow for a bulk vector Dzyaloshinsky-Moriya interaction. Here, we demonstrate current-induced domain wall motion in Fe3GeTe2 flakes, in which the maximum domain wall velocity is an order of magnitude higher than those reported in previous studies. In heterostructures with Pt or W layers on top of the Fe3GeTe2 flakes, domain walls can be moved via a combination of spin transfer and spin-orbit torques. The competition between these torques leads to a change in the direction of domain wall motion with increasing magnitude of the injected current. In this work, the researchers realize the current-induced motion of Néel type chiral domain walls via spin-transfer-torque in the pristine van der Waals ferromagnet Fe3GeTe2 and via spin-orbit-torques in heterostructures with platinum or tungsten. [ABSTRACT FROM AUTHOR]

Ischemic heart disease is among the primary causes of cardiovascular-related deaths worldwide. Conventional treatments including surgical interventions and medical therapies aid in preventing further damage to heart muscle but are unable to provide a permanent solution. In recent years, stem cell therapy has emerged as an attractive alternative to restore damaged myocardium after myocardial injury. Allogeneic (donor-derived) mesenchymal stem cells (MSCs) have shown great promise in preclinical and clinical studies, making them the most widely accepted candidates for cardiac cell therapy. MSCs promote cardiac repair by modulating host immune system and secreting various soluble factors, of which prostaglandin E2 (PGE2) is an important one. PGE2 plays a significant role in regulating cardiac remodeling following myocardial injury. In this review, we provide an overview of allogeneic MSCs as candidates for myocardial regeneration with a focus on the role of the PGE2/cyclooxygenase-2 (COX2) pathway in mediating these effects. Key words: mesenchymal stem cells, COX2, PGE2, cardiac ischemia, immunoprivilege, cell therapy. La maladie cardiaque ischemique est parmi les principales causes de deces liees au systeme cardiovasculaire a l'echelle mondiale. Les traitements classiques, y compris les interventions chirurgicales et les traitements medicaux, contribuent a la prevention de plus de dommages au muscle cardiaque, mais ne sont pas en mesure de fournir une solution definitive. Au cours des dernieres annees, le traitement par les cellules souches s'est revele constituer un autre choix attrayant pour le retablissement du myocarde endommage a la suite de lesions myocardiques. Les cellules souches mesenchymateuses (CSM) allogeniques (issues de donneurs) se sont revelees tres prometteuses dans les etudes precliniques et cliniques, ce qui en a fait les candidates les plus largement acceptees pour la therapie cellulaire cardiaque. Les CSM favorisent la reparation du creur par l'intermediaire de la modulation du systeme immunitaire de l'hote et la secretion de divers facteurs solubles, dont la PGE2 est l'une des plus importantes. La PGE2 joue un role important dans la regulation du remodelage du creur a la suite de lesions cardiaques. Dans cet article de synthese, nous of frons un aperqu des CSM allogeniques en tant que candidates pour la regenerescence du myocarde, avec une attention particuliere sur le role de la voie de signalisation PGE2/COX2 dans la mediation de ces effets. [Traduit par la Redaction] Mots-cles: cellules souches mesenchymateuses, COX2, PGE2, ischemie cardiaque, immunoprivilege, therapie cellulaire., Introduction Cardiovascular diseases are the leading cause of deaths around the globe, consuming nearly 17.9 million lives annually (World Health Organization 2017). In Canada alone, these deaths account for almost [...]

Background: All women with hyperglycemia in pregnancy (HIP) require optimal care. With western Uttarakhand alone recording a HIP prevalence of 9.7%, the successful implementation of HIP guidelines pan-India at primary healthcare level becomes paramount. Aim and objective: The present cross-sectional study aimed to assess the baseline awareness of medical undergraduates regarding HIP management protocols assuming higher their knowledge better the successful implementation of these guidelines within the community. Methodology: A descriptive study was carried out among 309 medical undergraduates at a private teaching institute in Uttarakhand. Data was collected using a selfadministered, pre-tested questionnaire. Based on individual knowledge scores, participants were subdivided into: good (score≥24), moderate (score 12-24), and poor (score<12) knowledge categories. Data were analyzed using Statistical Package for Social Sciences. Results: Most subjects (92.2%) reported reading Indian textbooks on obstetrics; despite this, only 3.6% of subjects had good awareness of the protocols. Sub-domain analysis showed while 90.0% of respondents had a fair understanding of the disease basics, more than two-thirds lagged in recollecting its standard diagnostic and management protocols including the role of health workers. Conclusion: Most medical undergraduates have overall poor-to-moderate awareness of HIP management especially the diagnostic and management protocols including the role of health workers. [ABSTRACT FROM AUTHOR]