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1. Oral Health-Related Quality of Life, A Proxy of Poor Outcomes in Patients on Peritoneal Dialysis

Author

Tungsanga, Kriang, Praditpornsilpa, Kearkiat, Chutsawan, Tanittha, Pongpirul, Krit, Triamamornwooth, Kanittha, Towannang, Piyaporn, Lorvinitnun, Pichet, Sritippayawan, Suchai, Halue, Guttiga, Tangjittrong, Kittisak, Poonvivatchaikarn, Ussanee, Buranaosot, Somphon, Nilvarangkul, Sukit, Somboonsilp, Wanida, Wongtrakul, Pimpong, Boonyakrai, Chanchana, Narenpitak, Surapong, Tatiyanupanwong, Sajja, Saikong, Wadsamon, Uppamai, Sriphrae, Phisutrattanaporn, Jarubut, Panyatong, Setthapon, Taruangsri, Puntapong, Chieochanthanakij, Rutchanee, Lounseng, Niwat, Wongpiang, Angsuwarin, Treamtrakanpon, Worapot, Rattanasoonton, Peerapach, Lukrat, Narumon, Songviriyavithaya, Phichit, Parinyasiri, Uraiwan, Cheawchanwattana, Areewan, Purisinsith, Sirirat, Kanjanabuch, Patnarin, Phannajit, Jeerath, Kanjanabuch, Talerngsak, Puapatanakul, Pongpratch, Johnson, David W., Perl, Jeffrey, and Robinson, Bruce

Published
2022
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5. Association of Local Unit Sampling and Microbiology Laboratory Culture Practices With the Ability to Identify Causative Pathogens in Peritoneal Dialysis-Associated Peritonitis in Thailand

Author

Praditpornsilpa, Kearkiat, Cheawchanwattana, Areewan, Towannang, Piyaporn, Triamamornwooth, Kanittha, Thongbor, Nisa, Aiyasanon, Nipa, Kaewboonsert, Donkum, Uttayotha, Pensri, Sopassathit, Wichai, Pitakmongkol, Salakjit, Poonvivatchaikarn, Ussanee, Jaroenpattrawut, Bunpring, Buranaosot, Somphon, Nilvarangkul, Sukit, Satitkan, Warakoan, Somboonsilp, Wanida, Wongtrakul, Pimpong, Tongpliw, Ampai, Pullboon, Anocha, Jankramol, Montha, Wechpradit, Apinya, Kleebchaiyaphum, Chadarat, Saikong, Wadsamon, Panya, Worauma, Thaweekote, Siriwan, Uppamai, Sriphrae, Phisutrattanaporn, Jarubut, Sirinual, Sirirat, Panyatong, Setthapon, Taruangsri, Puntapong, Prasertkul, Boontita, Buanet, Thanchanok, Passorn, Panthira, Luksanaprom, Rujira, Wongpiang, Angsuwarin, Chaiwut, Metinee, Phaichan, Ruchdaporn, Rattanasoonton, Peerapach, Thongsiw, Wanlaya, Lukrat, Narumon, Thaitrng, Sayumporn, Laoong, Yupha, Pikul, Niparat, Rukchart, Navarat, Sukmee, Korawee, Chantarungsri, Wandee, Kanjanabuch, Talerngsak, Chatsuwan, Tanittha, Udomsantisuk, Nibondh, Nopsopon, Tanawin, Puapatanakul, Pongpratch, Halue, Guttiga, Lorvinitnun, Pichet, Tangjittrong, Kittisak, Narenpitak, Surapong, Boonyakrai, Chanchana, Tatiyanupanwong, Sajja, Chieochanthanakij, Rutchanee, Treamtrakanpon, Worapot, Parinyasiri, Uraiwan, Lounseng, Niwat, Songviriyavithaya, Phichit, Sritippayawan, Suchai, Eiam-Ong, Somchai, Tungsanga, Kriang, Johnson, David W., Robinson, Bruce, and Perl, Jeffrey

Published
2021
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8. Mortality rates and a clinical predictive model for the elderly on maintenance hemodialysis: A large observational cohort study of 17,354 Asian patients

Author

Noppakun, Kajohnsak, primary, Nochaiwong, Surapon, additional, Tantraworasin, Apichat, additional, Khorana, Jiraporn, additional, Susantitaphong, Paweena, additional, Lumpaopong, Adisorn, additional, Sritippayawan, Suchai, additional, Ophascharoensuk, Vuddhidej, additional, and Ruengorn, Chidchanok, additional

Published
2023
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10. Mortality Rates and a Clinical Predictive Model for the Elderly on Maintenance Hemodialysis: A Large Observational Cohort Study of 17,354 Asian Patients.

Author

Noppakun, Kajohnsak, Nochaiwong, Surapon, Tantraworasin, Apichat, Khorana, Jiraporn, Susantitaphong, Paweena, Lumpaopong, Adisorn, Sritippayawan, Suchai, Ophascharoensuk, Vuddhidej, and Ruengorn, Chidchanok

Subjects
DEATH rate, ASIANS, COHORT analysis, DISEASE risk factors, KARNOFSKY Performance Status
Abstract

Introduction: Mortality following hemodialysis initiation may influence the decision to initiate hemodialysis in elderly patients. Our objective is to demonstrate mortality following hemodialysis initiation in elderly patients (≥70 years) and to derive a prediction risk score based on clinical and laboratory indicators to determine risk of all-cause mortality in patients aged ≥80 years. Methods: We identified elderly patients (≥70 years) who initiated maintenance hemodialysis between January 2005 and December 2016 using data from the Thai Renal Replacement Therapy (TRT) registry. The mortality rate was determined based on age categories. A predictive risk score for all-cause mortality was created for 4,451 patients aged ≥80 years by using demographics, laboratory values, and interview-based parameters. Using a flexible parametric survival analysis, we predicted mortality 3 months, 6 months, 1 year, 5 years, and 10 years after hemodialysis initiation. Results: 17,354 patients (≥70 years) were included, mean age 76.9 ± 5.1 years, 46.5% male, and 6,309 (36.4%) died. Patients aged <80 years had a median survival time of 110.6 months. A 9-point risk score was developed to predict mortality in patients aged ≥80 years: age >85 years, male, body mass index <18.5 kg/m2, hemoglobin <10.0 g/dL, albumin <3.5 g/dL, substantial assistance required in daily living (1 point each), and Karnofsky Performance Status (KPS) score <50 (3 points). C-statistic of 0.797 indicated high model discrimination. Internal validation demonstrated good agreement between observed and anticipated mortalities. Conclusions: Hemodialysis is appropriate for patients aged 70–80 years. A risk score for mortality in patients aged ≥80 years has been developed. The score is based on seven readily obtainable and evaluable clinical characteristics. [ABSTRACT FROM AUTHOR]

Published
2024
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12. An induced pluripotent stem cell line (MUSIi019-A) generated from a patient with distal renal tubular acidosis carrying a compound heterozygous mutation in solute carrier family 4 member 1 (SLC4A1) gene

Author

Kaewboonlert, Narissara, primary, Wattanapanitch, Methichit, additional, Praditsap, Oranud, additional, Deejai, Nipaporn, additional, Chanprasert, Chutima, additional, Sawasdee, Nunghathai, additional, Nettuwakul, Choochai, additional, Wanachiwanawin, Wanchai, additional, Sritippayawan, Suchai, additional, Thamtarana, Prapaporn Jungtrakoon, additional, Yenchitsomanus, Pa-thai, additional, and Rungroj, Nanyawan, additional

Published
2023
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13. Constipation and clinical outcomes in peritoneal dialysis: Results from Thailand PDOPPS.

Author

Halue, Guttiga, Tharapanich, Huttaporn, Phannajit, Jeerath, Kanjanabuch, Talerngsak, Banjongjit, Athiphat, Lorvinitnun, Pichet, Sritippayawan, Suchai, Sopassathit, Wichai, Poonvivatchaikarn, Ussanee, Buranaosot, Somphon, Somboonsilp, Wanida, Wongtrakul, Pimpong, Boonyakrai, Chanchana, Narenpitak, Surapong, Tatiyanupanwong, Sajja, Saikong, Wadsamon, Uppamai, Sriphrae, Panyatong, Setthapon, Chieochanthanakij, Rutchanee, and Lounseng, Niwat

Subjects
PERITONEAL dialysis, CONSTIPATION, PROPORTIONAL hazards models, TREATMENT effectiveness, PATIENT reported outcome measures
Abstract

Background: Patient‐reported outcome measures (PROMs) are widely recognized as valuable predictors of clinical outcomes in peritoneal dialysis (PD). Our study aimed to explore the connections between patient‐reported constipation and clinical outcomes. Methods: We assessed constipation in patients across 22 facilities participating in the Thailand Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) from 2014 to 2017. Constipation diagnosis utilized objective assessment tools such as the Bristol stool form scale (BSFS) and a self‐reported questionnaire known as the constipation severity score (CSS). The BSFS is a 7‐level scale that visually inspects feces based on texture and morphology, while the CSS measures constipation duration and severity using a 5‐point Likert scale for various factors. We employed Cox proportional hazards model regression to determine the associations between constipation and clinical outcomes, including mortality, hemodialysis (HD) transfer and peritonitis. Results: Among 975 randomly selected PD patients from 22 facilities, 845 provided written informed consent, and 729 completed CSS questionnaire. Constipation was prevalent in the PD population (13%), particularly among older patients, those who were caregiver dependent, had diabetes and poorer nutritional status (indicated by lower time‐averaged serum albumin, potassium, creatinine and phosphate concentrations). Twenty‐seven percent of which experiencing symptoms of constipation for over a year. Notably, self‐reported constipation at baseline was significantly associated with a shorter time to first peritonitis and higher rates of peritonitis and death. However, no significant association was found between constipation and HD transfer after adjusting for various factors, including age, gender, PD vintage, comorbidities, shared frailty by study sites and serum albumin. Conclusion: Patient‐reported constipation independently correlated with increased risks of peritonitis and all‐cause mortality, though no such correlation was observed with HD transfer. These findings underscore the need for further investigation to identify effective interventions for constipation in PD patients. [ABSTRACT FROM AUTHOR]

Published
2023
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14. Enhancing healthcare quality and outcomes for peritoneal dialysis patients in Thailand: An evaluation of key performance indicators and PDOPPS cohort representativeness.

Author

Boongird, Sarinya, Phannajit, Jeerath, Kanjanabuch, Talerngsak, Chuengsaman, Piyatida, Dandecha, Phongsak, Halue, Guttiga, Lorvinitnun, Pichet, Boonyakrai, Chanchana, Treamtrakanpon, Worapot, Tatiyanupanwong, Sajja, Lounseng, Niwat, Perl, Jeffrey, Johnson, David W., Pecoits‐Filho, Roberto, Sritippayawan, Suchai, Tungsanga, Kriang, Kantachuvesiri, Surasak, and Ophascharoensuk, Vuddhidej

Subjects
PERITONEAL dialysis, HEMODIALYSIS patients, LOGISTIC regression analysis, KEY performance indicators (Management), TREATMENT effectiveness
Abstract

Aim: To assess whether the peritoneal dialysis (PD) centres included in the Peritoneal Dialysis Outcomes and Practise Patterns Study (PDOPPS) in Thailand are representative of other PD centres in the country, based on 8 key performance indicators (KPIs 1–8). Methods: A retrospective analysis was conducted comparing PD‐related clinical outcomes between PD centres included in the PDOPPS (the PDOPPS group) and those not included (the non‐PDOPPS group) from January 2018 to December 2019. Logistic regression analysis was used to identify predictors associated with achieving the target KPIs. Results: Of 181 PD centres, 22 (12%) were included in the PDOPPS. PD centres in the PDOPPS group were larger and tended to serve more PD patients than those in the non‐PDOPPS group. However, the process and outcome KPIs (KPIs 1–8) were comparable between the 2 groups. Large hospitals (≥120 beds), providing care to ≥100 PD cases and having experience for >10 years were independent predictors of achieving the peritonitis rate target of <0.5 episodes/year. Most PD centres in Thailand showed weaknesses in off‐target haemoglobin levels and culture‐negative peritonitis rate. Conclusions: The PD centres included in Thai PDOPPS were found to be representative of other PD centres in Thailand in terms of clinical outcomes. Thus, Thai PDOPPS findings may apply to the broader PD population in Thailand. Summary at a glance: We investigated whether the PD centres included in PDOPPS were representative of other PD centres in Thailand using the national Thai key performance indicators.The PDOPPS centres had comparable process and clinical outcomes and barriers to those of other PD centres in Thailand.Key performance indicators can enhance the quality of PD care by facilitating the identification and prioritisation of improvement areas. [ABSTRACT FROM AUTHOR]

Published
2023
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17. Oral Health-Related Quality of Life, A Proxy of Poor Outcomes in Patients on Peritoneal Dialysis

Author

Purisinsith, Sirirat, primary, Kanjanabuch, Patnarin, additional, Phannajit, Jeerath, additional, Kanjanabuch, Talerngsak, additional, Puapatanakul, Pongpratch, additional, Johnson, David W., additional, Pongpirul, Krit, additional, Perl, Jeffrey, additional, Robinson, Bruce, additional, Tungsanga, Kriang, additional, Praditpornsilpa, Kearkiat, additional, Chutsawan, Tanittha, additional, Triamamornwooth, Kanittha, additional, Towannang, Piyaporn, additional, Lorvinitnun, Pichet, additional, Sritippayawan, Suchai, additional, Halue, Guttiga, additional, Tangjittrong, Kittisak, additional, Poonvivatchaikarn, Ussanee, additional, Buranaosot, Somphon, additional, Nilvarangkul, Sukit, additional, Somboonsilp, Wanida, additional, Wongtrakul, Pimpong, additional, Boonyakrai, Chanchana, additional, Narenpitak, Surapong, additional, Tatiyanupanwong, Sajja, additional, Saikong, Wadsamon, additional, Uppamai, Sriphrae, additional, Phisutrattanaporn, Jarubut, additional, Panyatong, Setthapon, additional, Taruangsri, Puntapong, additional, Chieochanthanakij, Rutchanee, additional, Lounseng, Niwat, additional, Wongpiang, Angsuwarin, additional, Treamtrakanpon, Worapot, additional, Rattanasoonton, Peerapach, additional, Lukrat, Narumon, additional, Songviriyavithaya, Phichit, additional, Parinyasiri, Uraiwan, additional, and Cheawchanwattana, Areewan, additional

Published
2022
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18. Loss-of-function mutations of SCN10A encoding NaV1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease

Author

Nettuwakul, Choochai, Praditsap, Oranud, Sawasdee, Nunghathai, Rungroj, Nanyawan, Ruamyod, Katesirin, Watanapa, Wattana B., Junking, Mutita, Sangnual, Sittideth, Sritippayawan, Suchai, Cheunsuchon, Boonyarit, Chuawattana, Duangporn, Rojsatapong, Santi, Chaowagul, Wipada, Dib-Hajj, Sulayman D., Waxman, Stephen G., and Yenchitsomanus, Pa-thai

Published
2018
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19. Additional file 1 of Impaired trafficking and instability of mutant kidney anion exchanger 1 proteins associated with autosomal recessive distal renal tubular acidosis

Author

Deejai, Nipaporn, Sawasdee, Nunghathai, Nettuwakul, Choochai, Wanachiwanawin, Wanchai, Sritippayawan, Suchai, Yenchitsomanus, Pa-thai, and Rungroj, Nanyawan

Abstract

Additional file 1: Table S1: PCR primers for amplification of all exons and exon-intron boundaries of the SLC4A1 gene. Table S2: Clinical and laboratory data of patient (II:1). Table S3: Results of bioinformatic analyses of the T444N mutation using VarCards web-based program. Fig. S1: The original and unprocessed versions of Fig. 1c. Fig. S2: The original and unprocessed versions of Fig. 3a. Fig. S3: Cellular localization of wild-type and mutant kAE1 proteins in HEK293T cells detected by immunofluorescence assay. Fig. S4: The original blot and unprocessed versions of Fig. 5a. Fig. S5: The original blot and unprocessed versions of Fig. 5b.

Published
2022
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22. Supplemental Material, sj-pdf-1-ptd-10.1177_0896860821993950 - Implementation of PDOPPS in a middle-income country: Early lessons from Thailand

Author

Kanjanabuch, Talerngsak, Puapatanakul, Pongpratch, Halue, Guttiga, Lorvinitnun, Pichet, Tangjittrong, Kittisak, Pongpirul, Krit, Narenpitak, Surapong, Boonyakrai, Chanchana, Tatiyanupanwong, Sajja, Chieochanthanakij, Rutchanee, Treamtrakanpon, Worapot, Parinyasiri, Uraiwan, Lounseng, Niwat, Songviriyavithaya, Phichit, Sritippayawan, Suchai, Perl, Jeffrey, Pecoits-Filho, Roberto, Robinson, Bruce, Davies, Simon J, Johnson, David W, and Tungsanga, Kriang

Subjects
Medicine
Abstract

Supplemental Material, sj-pdf-1-ptd-10.1177_0896860821993950 for Implementation of PDOPPS in a middle-income country: Early lessons from Thailand by Talerngsak Kanjanabuch, Pongpratch Puapatanakul, Guttiga Halue, Pichet Lorvinitnun, Kittisak Tangjittrong, Krit Pongpirul, Surapong Narenpitak, Chanchana Boonyakrai, Sajja Tatiyanupanwong, Rutchanee Chieochanthanakij, Worapot Treamtrakanpon, Uraiwan Parinyasiri, Niwat Lounseng, Phichit Songviriyavithaya, Suchai Sritippayawan, Jeffrey Perl, Roberto Pecoits-Filho, Bruce Robinson, Simon J Davies, David W Johnson, Kriang Tungsanga and on behalf of International and Thailand PDOPPS Steering Groups in Peritoneal Dialysis International

Published
2021
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24. Spiritual well‐being and its relationship with patient characteristics and other patient‐reported outcomes in peritoneal dialysis patients: Findings from the PDOPPS.

Author

Cheawchanwattana, Areewan, Kanjanabuch, Talerngsak, Puapatanakul, Pongpratch, Narenpitak, Surapong, Halue, Guttiga, Tungsanga, Kriang, Tatiyanupanwong, Sajja, Lorvinitnun, Pichet, Sritippayawan, Suchai, Chieochanthanakij, Rutchanee, Tungsanga, Somkanya, Thamcharoen, Natanong, Pongpirul, Krit, Shen, Jenny I., Johnson, David W., Davies, Simon J., Finkelstein, Fredric O., Perl, Jeffrey, and Robinson, Bruce

Subjects
PERITONEAL dialysis, HEMODIALYSIS patients, PATIENT reported outcome measures, PATIENT education, MENTAL depression
Abstract

Background: Spiritual well‐being (SWB), an individual's understanding of the meaning and purpose of life, may help patients with chronic or terminal illnesses cope with their diseases. This study aimed to assess SWB in patients on peritoneal dialysis (PD), as well as its relationship with patient characteristics and patient‐reported outcomes (PRO). Methods: The data were obtained from questionnaires that formed part of the PD Outcomes and Practice Patterns Study (PDOPPS). Measures used in this study were SWB scores derived from the WHO quality of life, spirituality, religiousness and personal beliefs (WHOQOL‐SRPB) tool including 32 items from eight facets; physical (PCS) and mental component summary (MCS) scores of the 12‐Item Short‐Form Health Survey (SF‐12), Center of Epidemiologic Studies Depression Scale‐10 (CES‐D‐10) scores, burden of kidney disease scores and functional status scores. Results: Overall, 529 out of 848 participants (62%) completely responded to the questionnaires and were included in the analysis. Over two‐thirds of PD patients (70%) had moderate or higher SWB scores. The SWB scores were significantly lower in patients with age >65 years and unemployed status. SWB scores positively correlated with higher PCS, MCS, burden of kidney disease scores and functional status scores, while negatively correlated with depression scores by CES‐D‐10 scale. Patients who reported significant depressive symptoms (CES‐D‐10 score ≥ 10) had significantly lower SWB scores. Conclusion: Better SWB was significantly associated with better health‐related QOL (HRQOL) and the absence of depressive symptoms. SWB may be an essential consideration in the delivery of high‐quality PD. SUMMARY AT A GLANCE: This study examined spiritual well‐being (SWB, the understanding of the meaning and purpose of life by the patient), which is an unexplored area in the care of PD patients. It showed that SWB has a close relation with quality of life. The result suggests that SWB may be a target for intervention and patient education. [ABSTRACT FROM AUTHOR]

Published
2022
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25. Association of Local Unit Sampling and Microbiology Laboratory Culture Practices With the Ability to Identify Causative Pathogens in Peritoneal Dialysis-Associated Peritonitis in Thailand

Author

Kanjanabuch, Talerngsak, primary, Chatsuwan, Tanittha, additional, Udomsantisuk, Nibondh, additional, Nopsopon, Tanawin, additional, Puapatanakul, Pongpratch, additional, Halue, Guttiga, additional, Lorvinitnun, Pichet, additional, Tangjittrong, Kittisak, additional, Narenpitak, Surapong, additional, Boonyakrai, Chanchana, additional, Tatiyanupanwong, Sajja, additional, Chieochanthanakij, Rutchanee, additional, Treamtrakanpon, Worapot, additional, Parinyasiri, Uraiwan, additional, Lounseng, Niwat, additional, Songviriyavithaya, Phichit, additional, Sritippayawan, Suchai, additional, Eiam-Ong, Somchai, additional, Tungsanga, Kriang, additional, Johnson, David W., additional, Robinson, Bruce, additional, Perl, Jeffrey, additional, Praditpornsilpa, Kearkiat, additional, Cheawchanwattana, Areewan, additional, Towannang, Piyaporn, additional, Triamamornwooth, Kanittha, additional, Thongbor, Nisa, additional, Aiyasanon, Nipa, additional, Kaewboonsert, Donkum, additional, Uttayotha, Pensri, additional, Sopassathit, Wichai, additional, Pitakmongkol, Salakjit, additional, Poonvivatchaikarn, Ussanee, additional, Jaroenpattrawut, Bunpring, additional, Buranaosot, Somphon, additional, Nilvarangkul, Sukit, additional, Satitkan, Warakoan, additional, Somboonsilp, Wanida, additional, Wongtrakul, Pimpong, additional, Tongpliw, Ampai, additional, Pullboon, Anocha, additional, Jankramol, Montha, additional, Wechpradit, Apinya, additional, Kleebchaiyaphum, Chadarat, additional, Saikong, Wadsamon, additional, Panya, Worauma, additional, Thaweekote, Siriwan, additional, Uppamai, Sriphrae, additional, Phisutrattanaporn, Jarubut, additional, Sirinual, Sirirat, additional, Panyatong, Setthapon, additional, Taruangsri, Puntapong, additional, Prasertkul, Boontita, additional, Buanet, Thanchanok, additional, Passorn, Panthira, additional, Luksanaprom, Rujira, additional, Wongpiang, Angsuwarin, additional, Chaiwut, Metinee, additional, Phaichan, Ruchdaporn, additional, Rattanasoonton, Peerapach, additional, Thongsiw, Wanlaya, additional, Lukrat, Narumon, additional, Thaitrng, Sayumporn, additional, Laoong, Yupha, additional, Pikul, Niparat, additional, Rukchart, Navarat, additional, Sukmee, Korawee, additional, and Chantarungsri, Wandee, additional

Published
2021
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26. Implementation of PDOPPS in a middle-income country: Early lessons from Thailand

Author

Kanjanabuch, Talerngsak, primary, Puapatanakul, Pongpratch, additional, Halue, Guttiga, additional, Lorvinitnun, Pichet, additional, Tangjittrong, Kittisak, additional, Pongpirul, Krit, additional, Narenpitak, Surapong, additional, Boonyakrai, Chanchana, additional, Tatiyanupanwong, Sajja, additional, Chieochanthanakij, Rutchanee, additional, Treamtrakanpon, Worapot, additional, Parinyasiri, Uraiwan, additional, Lounseng, Niwat, additional, Songviriyavithaya, Phichit, additional, Sritippayawan, Suchai, additional, Perl, Jeffrey, additional, Pecoits-Filho, Roberto, additional, Robinson, Bruce, additional, Davies, Simon J, additional, Johnson, David W, additional, and Tungsanga, Kriang, additional

Published
2021
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27. Barriers to and constraints of acute peritoneal dialysis in acute kidney injury: A nationwide survey

Author

Treamtrakanpon, Worapot, primary, Kanjanabuch, Talerngsak, additional, Nopsopon, Tanawin, additional, Chuengsaman, Piyatida, additional, Dandecha, Phongsak, additional, Boongird, Sarinya, additional, Khositrangsikun, Kamol, additional, Wongluechai, Laddaporn, additional, Tatiyanupanwong, Sajja, additional, Puapatanakul, Pongpratch, additional, Srisawat, Nattachai, additional, Eiam-Ong, Somchai, additional, Johnson, David W, additional, Sritippayawan, Suchai, additional, and Kantachuvesiri, Surasak, additional

Published
2021
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30. Serum Galactomannan Index for the Rapid Diagnosis of Fungal Peritonitis in Patients With Peritoneal Dialysis

Author

Chamroensakchai, Tamonwan, primary, Manuprasert, Wasin, additional, Puapatanakul, Pongpratch, additional, Saejew, Thunvarat, additional, Leelahavanichkul, Asada, additional, Chatsuwan, Tanittha, additional, Halue, Guttiga, additional, Lorvinitnun, Pichet, additional, Tangjittrong, Kittisak, additional, Pongpirul, Krit, additional, Tungsanga, Kriang, additional, Eiam-Ong, Somchai, additional, Johnson, David W., additional, Kanjanabuch, Talerngsak, additional, Towannang, Piyaporn, additional, Thongbor, Nisa, additional, Sritippayawan, Suchai, additional, Aiyasanon, Nipa, additional, Kaewboonsert, Donkum, additional, Uttayotha, Pensri, additional, Sopassathit, Wichai, additional, Pitakmongkol, Salakjit, additional, Poonvivatchaikarn, Ussanee, additional, Jaroenpattrawut, Bunpring, additional, Buranaosot, Somphon, additional, Nilvarangkul, Sukit, additional, Satitkan, Warakoan, additional, Somboonsilp, Wanida, additional, Wongtrakul, Pimpong, additional, Tongpliw, Ampai, additional, Pullboon, Anocha, additional, Boonyakrai, Chanchana, additional, Jankramol, Montha, additional, Narenpitak, Surapong, additional, Wechpradit, Apinya, additional, Tatiyanupanwong, Sajja, additional, Kleebchaiyaphum, Chadarat, additional, Saikong, Wadsamon, additional, Panya, Worauma, additional, Thaweekote, Siriwan, additional, Uppamai, Sriphrae, additional, Phisutrattanaporn, Jarubut, additional, Sirinual, Sirirat, additional, Panyatong, Setthapon, additional, Taruangsri, Puntapong, additional, Prasertkul, Boontita, additional, Buanet, Thanchanok, additional, Chieochanthanakij, Rutchanee, additional, Passorn, Panthira, additional, Lounseng, Niwat, additional, Luksanaprom, Rujira, additional, Wongpiang, Angsuwarin, additional, Chaiwut, Metinee, additional, Treamtrakanpon, Worapot, additional, Phaichan, Ruchdaporn, additional, Rattanasoonton, Peerapach, additional, Thongsiw, Wanlaya, additional, Lukrat, Narumon, additional, Thaitrng, Sayumporn, additional, Songviriyavithaya, Phichit, additional, Laoong, Yupha, additional, Pikul, Niparat, additional, Parinyasiri, Uraiwan, additional, Rukchart, Navarat, additional, Sukmee, Korawee, additional, and Chantarungsri, Wandee, additional

Published
2020
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31. Variation in Peritoneal Dialysis Time on Therapy by Country

Author

Lambie, Mark, Zhao, Junhui, McCullough, Keith, Davies, Simon J., Kawanishi, Hideki, Johnson, David W., Sloand, James A., Sanabria, Mauricio, Kanjanabuch, Talerngsak, Kim, Yong-Lim, Shen, Jenny I., Pisoni, Ronald L., Robinson, Bruce M., Perl, Jeffrey, Johnson, David, Perl, Jeffrey, Kawanishi, Hideki, Kim, Yong-Lim, Kanjanabuch, Talerngsak, Davies, Simon, Bernardo, Angelito, Pisoni, Ron, Robinson, Bruce, Shen, Jenny, Badve, Sunil, Boudville, Neil, Brown, Fiona, Chow, Josephine, Collins, John, Morton, Rachael, Wilson, Scott, Vychytil, Andreas, Van Biesen, Wim, Figueiredo, Ana, de Moraes, Thyago, Brunier, Gillian, Jain, Arsh, Jassal, Vanita, Nessim, Sharon, Oliver, Matthew, Price, Valerie, Quinn, Rob, Fang, Wei, Szeto, CC, Wang, Angela, Fukasawa, Mizuya, Ito, Yasuhiko, Ryuzaki, Munekazu, Tomo, Tadashi, Manzano, Alfonso Cueto, Marshall, Mark, Ljungman, Susanne, Boongird, Sarinya, Boonyakrai, Chanchana, Cheawchanwattana, Areewan, Halue, Guttiga, Sritippayawan, Suchai, Tatiyanupanwong, Sajja, Tungsanga, Kriang, Bowes, Elaine, Brown, Edwina, Fluck, Richard, Goh, Bak Leong, Hurst, Helen, Wilkie, Martin, Woodrow, Graham, Bender, Filitsa, Bernardini, Judith, Chatoth, Dinesh, Crabtree, John, Finkelstein, Fred, Ghaffari, Arshia, Mehrotra, Rajnish, Piraino, Beth, Schreiber, Martin, and Teitelbaum, Isaac

Published
2022
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34. Effects of Sustained‐Release Beraprost in Patients With Primary Glomerular Disease or Nephrosclerosis: CASSIOPEIR Study Results

Author

Nakamoto, Hidetomo, primary, Yu, Xue‐Qing, additional, Kim, Suhnggwon, additional, Origasa, Hideki, additional, Zheng, Hongguang, additional, Chen, Jianghua, additional, Joo, Kwon Wook, additional, Sritippayawan, Suchai, additional, Chen, Qinkai, additional, Chen, Hung‐Chun, additional, Tsubakihara, Yoshiharu, additional, Tamai, Hirofumi, additional, Song, Sang Heon, additional, Vaithilingam, Indralingam, additional, Lee, Kang Wook, additional, Shu, Kuo‐Hsiung, additional, Hok‐King Lo, Stanley, additional, Isono, Masanao, additional, Kurumatani, Hajimu, additional, Okada, Kiyonobu, additional, Kanoh, Hiroyuki, additional, Kiriyama, Takashi, additional, Yamada, Shunsuke, additional, and Fujita, Toshiro, additional

Published
2019
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35. Implementation of PDOPPS in a middle-income country: Early lessons from Thailand

Author

Kanjanabuch, Talerngsak, Puapatanakul, Pongpratch, Halue, Guttiga, Lorvinitnun, Pichet, Tangjittrong, Kittisak, Pongpirul, Krit, Narenpitak, Surapong, Boonyakrai, Chanchana, Tatiyanupanwong, Sajja, Chieochanthanakij, Rutchanee, Treamtrakanpon, Worapot, Parinyasiri, Uraiwan, Lounseng, Niwat, Songviriyavithaya, Phichit, Sritippayawan, Suchai, Perl, Jeffrey, Pecoits-Filho, Roberto, Robinson, Bruce, Davies, Simon J, Johnson, David W, and Tungsanga, Kriang

Abstract

Background: Despite the implementation of a ‘Peritoneal Dialysis (PD) First’ policy in Thailand since 2008, nationwide PD practices and patients’ outcomes have rarely been reported.Methods: As part of the multinational PD Outcomes and Practice Patterns Study (PDOPPS), PD patients from 22 PD centres from different geographic regions, sizes and affiliations, representing Thailand PD facilities, have been enrolled starting in May 2016. Demographic, clinical and laboratory data and patients’ outcomes were prospectively collected and analysed.Results: The pilot and implementation phases demonstrated excellent concordance between study data and validation data collected at enrolment. In the implementation phase, 848 PD patients (including 262 (31%) incident PD patients) were randomly sampled from 5090 patients in participating centres. Almost all participants (95%) performed continuous ambulatory PD (CAPD), and a high proportion had hypoalbuminemia (67%, serum albumin < 3.5 g/dL), anaemia (42%, haemoglobin <10 g/dL) and hypokalaemia (37%, serum potassium < 3.5 mmol/L). The peritonitis rate was 0.40 episodes/year, but the culture-negative rate was high (0.13 episodes/year, 28% of total episodes). The patients from PD clinics located in Bangkok metropolitan region had higher socio-economic status, more optimal nutritional markers, blood chemistries, haemoglobin level and lower peritonitis rates compared to the provincial regions, emphasizing the centre effect on key success factors in PD.Conclusions: Participation in the PDOPPS helps unveil the critical barriers to improving outcomes of PD patients in Thailand, including a high prevalence of hypokalaemia, anaemia, poor nutritional status and culture-negative peritonitis. These factors should be acted upon to formulate solutions and implement quality improvement on a national level.

Published
2022
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36. Barriers to and constraints of acute peritoneal dialysis in acute kidney injury: A nationwide survey

Author

Treamtrakanpon, Worapot, Kanjanabuch, Talerngsak, Nopsopon, Tanawin, Chuengsaman, Piyatida, Dandecha, Phongsak, Boongird, Sarinya, Khositrangsikun, Kamol, Wongluechai, Laddaporn, Tatiyanupanwong, Sajja, Puapatanakul, Pongpratch, Srisawat, Nattachai, Eiam-Ong, Somchai, Johnson, David W, Sritippayawan, Suchai, and Kantachuvesiri, Surasak

Abstract

This national survey of barriers to and constraints of acute peritoneal dialysis (aPD) in acute kidney injury (AKI) was performed by distributing an online questionnaire to all medical directors of public dialysis units registered with the Nephrology Society of Thailand during September–November 2019. One hundred and thirteen adult facilities responded to the survey covering 75 from 76 provinces (99%) of Thailand. aPD was performed in 66 centres (58%). In facilities where aPD practice was available, the utilization rate was relatively low (<10 cases/year) and limited to specific conditions, including HIV seropositive patients, previous receiving dialysis education and plan and difficult vascular access creation. Only 9% of facilities performed aPD routinely, but interestingly all such units permitted bedside catheter insertion by the nephrologists or internists. The major constraints placed on aPD practice were PD catheter insertion competency, timely catheter insertion support and the medical supporting team’s knowledge/competency deficits. aPD for AKI is underutilized in Thailand and limited by the inability to undertake timely PD catheter insertion and knowledge and competency deficits.

Published
2022
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37. Ertugliflozin and Slope of Chronic eGFR

Author

Cherney, David Z.I., Cosentino, Francesco, Dagogo-Jack, Samuel, McGuire, Darren K., Pratley, Richard, Frederich, Robert, Maldonado, Mario, Liu, Chih-Chin, Liu, Jie, Pong, Annpey, Cannon, Christopher P., Pozzi, Jose Maria, Maffei, Laura, Nardone, Lucrecia, Sessa, Horacio, Brasca, Daniela Garcia, Aizenberg, Diego, Baccaro, Claudia Emilce, Gelersztein, Elizabeth Silvana, Rosario, Fabian Calella Pedro, Leon de la Fuente, Ricardo, de Lapertosa, Silvia Gorban, Maldonado, Natacha, Cruciani, Adrian, Bartolacci, Ines, Hasbani, Eduardo, Frechtel, Gustavo, Papini, Nelson Rodriguez, Pereyra, Alejandro, Montana, Oscar, Zaidman, Cesar, Mansilla, Maria, Ayres, Bronte, Simpson, Richard, Glastras, Sarah, William, Maged, Davis, Timothy, Colquhoun, David, Proietto, Joseph, Roberts, Adam, Roberts, Anthony, Stuckey, Bronwyn, Wittert, Gary, Soldatos, Georgia, Vora, Parind, Kusljugic, Zumreta, Avdagic, Azra, Durak-Nalbantic, Azra, Ibrahimpasic, Kanita, Horozic, Bosanko, Spuzic, Muhamed, Soldat-Stankovic, Valentina, Stevanovic, Dragan, Koco, Damir, Jatic, Zaim, Terzic, Ibrahim, Potkonjak, Ljiljana Markovic, Prnjavorac, Besim, Radanovic, Aleksandar, Salihbasic, Muhamed, Dimitrov, Dimitar, Stoikov, Anastas, Damyanova, Velichka, Vasileva, Darina, Kirilov, Kiril, Lefterov, Ivailo, Lyubenova, Lyudmila, Raev, Dimitar, Tsanova, Veska, Mitkov, Mitko, Shumkova, Rositsa, Kichukov, Kostadin, Simeonova-Nikolova, Tatyana, Ekoe, Jean-Marie, Pandey, Shekhar A., Dumas, Richard, Woo, Vincent, Saunders, Kevin, Conway, James, Breger, Laurie, Constance, Christian, O'Mahony, Michael, Perron, Patrice, Garceau, Claude, Csanadi, Michael, Bourgeois, Ronald, Salter, Timothy, Frechette, Andre, Diaz, Ariel, Ransom, Thomas, Sanchez-Vallejo, Gregorio, Silva, Sandra Isabel Barrera, Mendoza, Jose Accini, Ortiz, Luis Garcia, Lozno, Hernan Yupanqui, de Salazar, Dora Molina, Arroyo, Julian Coronel, Orozco Linares, Luis Alejandro, Lenis Rendon, Claudia Patricia, Darko, Pocanic, Tusek, Srecko, Weiss, Sonja Slosic, Silvija, Canecki-Varzic, Velimir, Altabas, Sidbela, Zukanovic, Cikac, Tatjana, Vucak, Jasna, Cenan, Ljiljana, Boljkovac, Zrinka, Margetic, Srecko, Kranjcevic, Ksenija, Cop, Renata, Adamkova, Vera, Pavlina, Kyselova, Wasserburger, Bedrich, Hrdina, Tomas, Smolenakova, Katerina, Ketevan, Chagunava, Pagava, Zurab, Mamatsashvili, Merab, Burnadze, Koba, Chumburidze, Vakhtang, Lominadze, Zaza, Nikoleishvili, Lali, Kobulia, Bondo, Koberidze, Nana, Emukhvari, Nodar, Kipiani, Zviad, Metreveli, David, Glonti, Salome, Giorgadze, Elene, Shaburishvili, Tamaz, Chapidze, Gulnara, Gulua, Julieta, Gogorishvili, Irakli, Berukashvili, Ekaterine, Petriashvili, Shalva, Kurashvili, Givi, Elisaf, Moses, Bousboulas, Stavros, Tentolouris, Nikolaos, Tsioufis, Konstantinos, Lymperi, Sotiria, Luk, Andrea, Yiu, Kelvin Kai Hang, Tsang, Chiu Chi, Yeung, Vincent Tok Fai, Lee, Alex Pui-Wai, Tan, Kathryn Choon Beng, Wan Ma, Ronald Ching, Wudi, Krisztina Beatrix, Bujtor, Zoltan, Feher, Zsuzsanna, Koranyi, Laszlo, Paragh, Gyorgy, Vasas, Szilard, Pauker, Zsolt, Kesmarki, Nora, Takacs, Janos, Nagy, Laszlo, Salamon, Csaba, Papp, Zsuzsanna, Hajdu, Csaba, Abramov, Galina, Hussein, Osamah, Vishlitzky, Victor, Dicker, Dror, Darawsha, Mahmud, Itzhak, Baruch, Gavish, Dov, Wainstein, Julio, Lewis, Basil, Klainman, Eliezer, Katz, Amos, Elias, Mazen, Ness-Abramof, Rosane, Hayek, Tony, Orsi, Emanuela, Lembo, Giuseppe, Piatti, Piermarco, Consoli, Agostino, Berti, Sergio, Pugliese, Giuseppe, Derosa, Giuseppe, Paolisso, Giuseppe, Limone, Paolo Piero, Jang, Hak Chul, Lee, Moon-Kyu, Kim, Nam Hoon, Cha, Bong-Soo, Park, Kyong Soo, Yoon, Kun Ho, Ahn, Chul Woo, Lee, Kwan Woo, Baik, Sei Hyun, Pirags, Valdis, Pastare, Sigita, Kavaliauskiene, Jurate, Augusteniene, Audrone, Navickas, Antanas, Urbanavicius, Vaidotas, Kavaliauskiene, Roma, Sirutaviciene, Ausra, Llamas Esperon, Guillermo Antonio, Mesa, Juan Villagordoa, Garcia Hernandez, Pedro Alberto, Ceballos, Rosa Luna, Salinas, Carlos Aguilar, Galvez, Guillermo Gonzalez, Melendez-Mier, Guillermo, Orozco, Raul Aguilar, Crijns, Harry, Hoogenberg, Klaas, Voors-Pette, Christine, Lunt, Helen, Scott, Russell, Baker, John, Williams, Michael, Kerr, Jane Elizabeth, Denopol, Marian, Panelo, Araceli, Tirador, Louie, Aquitania, Grace, Rogelio, Gregorio, Amorado-Santos, Florence, Habaluyas, Ramoncito, Rosa, Allyn Sy, Palomares, Ellen, Ebo, Geraldine, Romero, Chela Marie, Gladczak, Joanna, Hawryluk, Jaroslaw, Franek, Edward, Lukaszewicz, Monika, Madej-Dmochowska, Aleksandra, Jeznach-Steinhagen, Anna, Sokolowski, Grzegorz, Ruxer, Jan, Karczmarczyk, Agnieszka, Krzyzagorska, Ewa, Wozniak, Iwona, Olech-Cudzik, Anna, Dwojak, Marek, Anand, Izabela, Strojek, Krzysztof, Czernecka, Ewa, Antkowiak-Piatyszek, Karolina, Rozanska, Aleksandra, Gadzinski, Waldemar, Mader, Piotr, Kuligowska-jakubowska, Monika, Arciszewska, Malgorzata, Stankiewicz, Andrzej, Cypryk, Katarzyna, Wittek, Andrzej, Sawer-Szewczyk, Joanna, Pieniazek, Adam, Negrisanu, Gabriela, Pletea, Noemi, Zaharie, Daniela, Pintilei, Ella, Cif, Adriana, Duma, Livia, Szilagyi, Iosif, Halmagyi, Ildiko, Morosanu, Magdalena, Munteanu, Mircea, Albota, Adrian, Popescu, Alexandrina, Enculescu, Dan Anton, Hancu, Nicolae, Nafornita, Valerica, Croitoru, Lacramioara, Sebestyen, Lucia Luana, Pavlysh, Elena, Nikolaev, Konstantin, Vishnevsky, Alexandr, Reshetko, Olga, Kvitkova, Liudmila, Barbarash, Olga, Rodionova, Tatiana, Shaydyuk, Oxana, Ershova, Olga, Chizhov, Petr, Berns, Svetlana, Rechkova, Elena, Yakushin, Sergey, Zanozina, Olga, Lukyanov, Yuri, Vorobeva, Elena, Zateyshchikov, Dmitry, Verbovaya, Nelly, Bolshakova, Olga, Khrustalev, Oleg, Strongin, Leonid, Bondar, Irina, Zalevskaya, Alsu, Filippova, Ekaterina, Chumakova, Galina, Repin, Alexey, Panov, Alexey, Zivkovic, Teodora Beljic, Petakov, Milan, Sumarac-Dumanovic, Mirjana, Brankovic, Georgina Pudar, Kendereski, Aleksandra, Stojic, Stevo, Macut, Djuro, Babikova, Jana, Teplanova, Miriam, Tomasova, Livia, Martinka, Emil, Lachova, Beata, Ivancova, Gabriela, Rociakova, Jana, Schroner, Zbynek, Donicova, Viera, Ilavska, Adriana, Raslova, Katarina, Africa, South, Distiller, Lawrence, Siebert, Heidi, Badat, Aysha, Blignaut, Suzanne, Sarvan, Mahomed, Govender, Thirumani, Gani, Mashra, Nortje, Hendrik, Mookadam, Mohamed, Naiker, Puvanesveri, de Jong, Douwe, Van Zyl, Louis, Seeber, Mary, Urbach-Bolus, Dorothea, Bayat, Junaid, Boyd, Warren, du Toit, Margaretha, Punt, Zelda, Arnold, Susan, Van Dyk, Christo, Robertson, Leslie Ivan, Kotze, Hester Johanna, Anders, Luts, Martin, Lundvall, Carl-Johan, Lindholm, Bengt-Olov, Tengmark, Dan, Curiac, Peter, Bosson, Pekka, Koskinen, Hajimirsadeghi, Ali, Huang, Chen-Ling, Jiang, Ju-Ying, Hsia, Te- Lin, Ueng, Kwo-Chang, Yang, Wei-Shiung, Lu, Yung-Chuan, Yang, Chwen-Yi, Sheu, Wayne Huey-Herng, Chiang, Chern-En, Yeh, Hung-I, Suwanwalaikorn, Sompongse, Kosachunhanun, Natapong, Sritippayawan, Suchai, Tejavanija, Sirakarn, Silaruks, Songkwan, Araz, Mustafa, Sari, Ramazan, Berker, Dilek Sensoz, Arslan, Muyesser Sayki, Godlevska, Olga, Chopey, Ivan, Teliatnikova, Zinaida, Kuskalo, Petro, Abrahamovych, Orest, Mankovskyi, Borys, Fushtey, Ivan, Myshanych, Galyna, Tykhonova, Susanna, Tseluyko, Vira, Koval, Olena, Parkhomenko, Oleksandr, Prokhorov, Oleksandr, Vayda, Myroslava, Martymianova, Larysa, Zharinova, Viktoriia, Prystupa, Lyudmyla, Pererva, Larysa, Kovalov, Oleksandr, Sokolova, Lyubov, Botsyurko, Volodymyr, Maslyanko, Vitaliy, Vlasenko, Maryna, Khomazyuk, Tetyana, Kulyk, Anna, Synenko, Volodymyr, Karpenko, Oleksandr, Mostovoy, Yuriy, Gyrina, Olga, Dolzhenko, Maryna, Donets, Oleksandra, Sorokina, Inna, Malynovsky, Yaroslav, Lysunets, Olena, Petrovskyy, Roman, Panina, Svitlana, Avornyo, Anthony, Eyre, Susannah, Ryan, John, Cardwell, Glenn, Robinson, Anthony, Clark, Rebecca, Issa, Basil, Weeraratne, Devinda, McCrimmon, Rory, Jones, Thomas, Philip, Sam, Beboso, Ronnie, Davies, Melanie, Kyriakidou, Christina, Saxena, Manish, Thomas, Hawys, Gowda, Madhu, Arif, Imrozia, Oyesile, Babatunde, Cecil, John, Brunskill, Jonathan Mark Edwin, Akinboboye, Olakunle, Akright, Laura, Arora, Chander, Ball, Eric, Benjamin, Sabrina, Budoff, Matthew, Cathcart, Harold, Daboul, Nizar, Denker, Paul, Garner, Andrew, Jabbour, Serge, Jaffrani, Naseem, Jeanfreau, Robert, Knutson, Thomas, Lillestol, Michael, McNeil, Donald, Nakhle, Samer, Randall, William, Mallepalli, Jyothi, Schmidt, Jay, Serje, Jorge, Shoemaker, James, Storey, Daniel, Warner, Alberta, Pimentel, Severino, Quintero, Luis, Galvez, Juan, Bernard, David, Cruz, Humberto, O'Donnell, Philip, Thawani, Hemant, Sorial, Ehab, Schwartzbard, Arthur, Agaiby, John, Garcia, Bernard, Cone, Clancy, Doshi, Ankur, Iranmanesh, Ali, Lingvay, Ildiko, Smith, Kimberly, McLean, Barry, Neutel, Joel, Odugbesan, Adeniyi, Sligh, Teresa, Lesh, Kurt, Rohr, Kathryn, Ajani, Dilawar, Daniel, Jerome, Cornett, George, Dykstra, Gary, Mahal, Sharan, Adams, Michael, Ramstad, David, Arif, Ahmed, Martin, Earl, Sastre, Ramon, Srivastava, Sunny, Feld, Lawrence, Bush, Kelvin, Shah, Vinay, Konigsberg, Sarah, Allaw, Mohammed, Kelly, Richard, MacGillivray, Brian, McGuire, Michael, Weinstein, Debra, Budhraja, Madhusudan, Tahirkheli, Naeem, Binker, Josefa, Bernstein, Marc, Andrawis, Nabil, Abdullah, Shuaib, Christensen, Tom, Khan, Misal, El Shahawy, Mahfouz, Tripathy, Devjit, Ranadive, Nandkishore, Grena, Paul, Villafuerte, Betty, Cook, Charles, Bautista, Jose, Marar, Isam, Kaunzinger, Christian, Bittar, Neville, Frias, Juan, Davit, Rajesh, Bays, Harold, Cohen, Robert, Garvey, William, Smith, Stephen, Ruiz, Jose-Luis, Hartman, Aaron, Diener, James, Chochinov, Ronald, Hunter, John, Aronoff, Stephen, Reed, Larry, Evans, John, Ackermann, Jeremy, Haaksma, James, Torres-Consuegra, Aurelio, Khan, Jalil, Yousuf, Kabir, Bermudez, Lidia, Lumicao, Benjamin, Olmeda, Jorge Torres, Kessler, Evan, Winnie, Michael, Lending, Robert, Razzaque, Naveed, McCartney, Michael, Munoz, Francisco, Buynak, Robert, Ables, Lilia Rodriguez, Makam, Sashi, Lozano, Josefina, Paez, Henry, Gore, Ashwini, Al-Karadsheh, Amer, Masri, Bassem, Gorrela, Sushma, Al-Amin, Jessie Louise, Alani, Firas, Haffizulla, Jason, Hsieh, Ron, Hernandez, Luis Castillo, Turner, Merle, French, William, Jetty, Preetham, Sheikh-Ali, Mae, Leggett, Richard, Perlman, Richard, Goldstein, Gary, Osea, Edgardo A., Bartkowiak, Anthony James, Gimness, Michael Paul, Higgins, Alexander John, Khan, Sohail Mohyuddin, Rahimi, Ali R, Shah, Anil Vallabhdas, Lillo, Joseph Leonard, Hartman, Israel Alejandro, Whitney, Edwin J., Johnston, Janice G., Juarez, Mario R., Perley, Michael J., Kahn, Brian Howard, Amine, Maged A., Pace, Michael Anthony, Peters, Shirin Sabina, Hidalgo, Horacio Augusto, Krichmar, Perry, and Sinha, Rabi Ranjan

Published
2021
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38. National feasibility survey of peritoneal dialysis key performance indicators in Thailand from provider perspective.

Author

Pongpirul, Krit, Kanjanabuch, Talerngsak, Puapatanakul, Pongpratch, Chuengsaman, Piyatida, Dandecha, Phongsak, Kingwatanakul, Pornchai, Sritippayawan, Suchai, Chittinandana, Anutra, Eiam‐Ong, Somchai, Vareesangthip, Kriengsak, and Tungsanga, Kriang

Subjects
PERITONEAL dialysis, KEY performance indicators (Management), LIKERT scale, FEASIBILITY studies, SURVEYS
Abstract

Background: Peritoneal dialysis (PD) has been the main method of renal replacement therapy under the "PD First" policy in Thailand since 2008. Initially, the proposed 13 key performance indicators (KPIs) raised feasibility concerns because of inequitable distribution of resources such as laboratory facilities and/or specialized health‐care staff for PD care throughout the country. Methods: Data availability and goals from the health‐care providers' perspective were explored using an online questionnaire survey for all PD centers registered with the Nephrology Society of Thailand from May to June 2016. The availability of essential data required for each KPI indicator to achieve the desired target was assessed using a 5‐point Likert scale. Results: Of the 197 centers, 119 responded to the survey (response rate of 60.41%). PD indicators with a high percentage of strongly disagree or disagree were "PD adequacy measured in the last 12 months" (26.83%), "Total weekly Kt/V ≥ 1.7" (24.59%), "3‐year PD technique survival" (21.31%), "Serum parathyroid levels within 150 to 500 pg/mL" (16.94%), and a "3‐year PD patient survival" (19.01%). As many as 34.17%, 39.19%, 27.27%, 28.93%, and 22.00%, respectively, did not anticipate that the targets could be achieved. Based on the findings from this survey, the national committee concluded that these indicators be removed, and only eight PD indicators were launched. Conclusion: Given the importance of KPIs for quality assurance and financial reimbursement, inputs from health‐care providers especially data availability and achievement of targets should be considered to ensure feasibility before the final list of indicators are launched. SUMMARY AT A GLANCE: This report is a summary of the results of a national study conducted in Thailand to assess the feasibility of reporting key performance indicators for peritoneal dialysis, which highlights clinician attitudes and the tensions inherent in developing standards, particularly in resource constrained environments. [ABSTRACT FROM AUTHOR]

Published
2020
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39. Effects of Sustained‐Release Beraprost in Patients With Primary Glomerular Disease or Nephrosclerosis: CASSIOPEIR Study Results.

Author

Nakamoto, Hidetomo, Yu, Xue‐Qing, Kim, Suhnggwon, Origasa, Hideki, Zheng, Hongguang, Chen, Jianghua, Joo, Kwon Wook, Sritippayawan, Suchai, Chen, Qinkai, Chen, Hung‐Chun, Tsubakihara, Yoshiharu, Tamai, Hirofumi, Song, Sang Heon, Vaithilingam, Indralingam, Lee, Kang Wook, Shu, Kuo‐Hsiung, Hok‐King Lo, Stanley, Isono, Masanao, Kurumatani, Hajimu, and Okada, Kiyonobu

Subjects
DRUG side effects, CHRONIC kidney failure, CONTROLLED release preparations, KIDNEY glomerulus diseases, CHRONICALLY ill, ADVERSE health care events
Abstract

TRK‐100STP, a sustained‐release preparation of the orally active prostacyclin analogue beraprost sodium, targets renal hypoxia. This study aimed to show the superiority of TRK‐100STP over placebos in patients with chronic kidney disease (with either primary glomerular disease or nephrosclerosis) to determine the recommended dose. CASSIOPEIR (Chronic Renal Failure Asian Study with Oral PGI2 Derivative for Evaluating Improvement of Renal Function) was a randomized, double‐blind, placebo‐controlled study conducted at 160 sites in seven Asia‐Pacific countries and regions. Eligible patients (n = 892) were randomized to TRK‐100STP 120, 240 μg, or placebo for a treatment period of up to 4 years. The primary efficacy endpoint was time to first occurrence of a renal composite: doubling of serum creatinine or occurrence of end‐stage renal disease. No significant differences were observed in composite endpoints between TRK‐100STP and placebo (P = 0.5674). Hazard ratios (95% CI) in the TRK‐100STP 120 and 240 μg vs. placebo groups were 0.98 (0.78, 1.22) and 0.91 (0.72, 1.14), respectively. The overall incidence of adverse events and adverse drug reactions was comparable between treatment arms. [ABSTRACT FROM AUTHOR]

Published
2020
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45. Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in End-Stage Renal Disease Patients Receiving Continuous Ambulatory Peritoneal Dialysis

Author

Koomanachai, Pornpan, primary, Landersdorfer, Cornelia B., additional, Chen, Gong, additional, Lee, Hee Ji, additional, Jitmuang, Anupop, additional, Wasuwattakul, Somkiat, additional, Sritippayawan, Suchai, additional, Li, Jian, additional, Nation, Roger L., additional, and Thamlikitkul, Visanu, additional

Published
2014
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46. Association between Human Prothrombin Variant (T165M) and Kidney Stone Disease

Author

Rungroj, Nanyawan, primary, Sudtachat, Nirinya, additional, Nettuwakul, Choochai, additional, Sawasdee, Nunghathai, additional, Praditsap, Oranud, additional, Jungtrakoon, Prapaporn, additional, Sritippayawan, Suchai, additional, Chuawattana, Duangporn, additional, Borvornpadungkitti, Sombat, additional, Predanon, Chagkrapan, additional, Susaengrat, Wattanachai, additional, and Yenchitsomanus, Pa-thai, additional

Published
2012
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47. Prothrombin Haplotype Associated With Kidney Stone Disease in Northeastern Thai Patients

Author

Rungroj, Nanyawan, primary, Sritippayawan, Suchai, additional, Thongnoppakhun, Wanna, additional, Paemanee, Atchara, additional, Sawasdee, Nunghathai, additional, Nettuwakul, Choochai, additional, Sudtachat, Nirinya, additional, Ungsupravate, Duangporn, additional, Praihirunkit, Pairao, additional, Chuawattana, Duangporn, additional, Akkarapatumwong, Varaporn, additional, Borvornpadungkitti, Sombat, additional, Susaengrat, Wattanachai, additional, Vasuvattakul, Somkiat, additional, Malasit, Prida, additional, and Yenchitsomanus, Pa-thai, additional

Published
2011
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50. Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in End-Stage Renal Disease Patients Receiving Continuous Ambulatory Peritoneal Dialysis

Author

Koomanachai, Pornpan, Landersdorfer, Cornelia B., Chen, Gong, Lee, Hee Ji, Jitmuang, Anupop, Wasuwattakul, Somkiat, Sritippayawan, Suchai, Li, Jian, Nation, Roger L., and Thamlikitkul, Visanu

Abstract

ABSTRACTColistin, administered intravenously as its inactive prodrug colistin methanesulfonate (CMS), is increasingly used as last-line therapy to combat multidrug-resistant Gram-negative bacteria. CMS dosing needs to be adjusted for renal function. The impact of continuous ambulatory peritoneal dialysis (CAPD) on the pharmacokinetics of both CMS and colistin has not been studied. No CMS dosing recommendations are available for patients receiving CAPD. Eight CAPD patients received a single intravenous CMS dose (150 mg colistin base activity [CBA]) over 30 min. Serial blood and dialysate samples, and cumulative urine where applicable, were collected over 25 h. CMS and colistin concentrations were determined by high-performance liquid chromatography. Population pharmacokinetic modeling and Monte Carlo simulations were conducted. The total body clearance of CMS (excluding CAPD clearance) was 1.77 liters/h (44%) [population mean (between-subject variability)], while CAPD clearance was 0.088 liter/h (64%). The population mean terminal half-life of CMS was 8.4 h. For colistin, the total clearance/fraction of CMS metabolized to colistin (fm) (excluding CAPD clearance) was 2.74 liters/h (50%), the CAPD clearance was 0.101 liter/h (34%), and the mean terminal half-life was 13.2 h. Monte Carlo simulations suggested a loading dose of 300 mg CBA on day 1 and a maintenance dose of either 150 mg or 200 mg CBA daily to achieve a target average steady-state plasma colistin concentration of 2.5 mg/liter. Clearance by CAPD was low for both CMS and formed colistin. Therefore, CMS doses should not be increased during CAPD. Modeling and simulation enabled us to propose the first evidence-based CMS dosage regimen for CAPD patients.

Published
2013
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