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6 results on '"Srikumar Padmalayam Sadanandan"'

1. List of contributors

Author

Gareeballah Osman Adam, Charles Oluwaseun Adetunji, Dickson Adom, Muhammad Akram, Adeola Ala, Idongesit E. Archibong, Maria Aslam, Muhammad Barkaat Azam, Mohammad Azharuddin, Anindita Behera, Maryam Behmanesh, Subhash Chandra, Abdulrahman Ahmed Chyad, Michael K. Danquah, Chukwuebuka Egbuna, Emmanuel Onyemaechi Eze, Franklyn N. Ezeonyebuchi, Shahira M. Ezzat, Masrat ul Gani, Ankita Gautam, Jonathan C. Ifemeje, Areeba Imtiaz, Zeenat Iqbal, Jaison Jeevanandam, Jyothi Kaparapu, Rohini Karunakaran, Shyam Sundar Kesh, Iram Khan, Saravanan Krishnan, M. Krishna Prasad, Barbara Krochmal-Marczak, Saikumar Manchala, Sheikh Mansoor, Rana M. Merghany, Mohd Aamir Mirza, G. Mohan Narasimha Rao, null Navneet, Alloysius Chibuike Ogodo, Chinenyenwa Ohia, Christopher Uche Okoronkwo, Olutosin Ademola Otekunrin, Santwana Padhi, Santwana Palai, Puja Patel, Kingsley C. Patrick-Iwuanyanwu, Kumar Ponnuchamy, Ibrahim Alhaji Sabo, Srikumar Padmalayam Sadanandan, Sarla Saklani, Mohamed A. Salem, Barbara Sawicka, Suhaib Shamas, Ajeet Singh, Bikarma Singh, Dominika Skiba, Ashokkumar Thirunavukkarasu, Foziyah Zakir, Saima Zameer, Ahmed Zayed, Chukwuemelie Zedech Uche, and Parisa Ziarati

Published
2022

3. Role of Zinc (Zn) in Human Reproduction: A Journey from Initial Spermatogenesis to Childbirth

Author

Vickram, Sundaram, primary, Rohini, Karunakaran, additional, Srinivasan, Subramanian, additional, Nancy Veenakumari, David, additional, Archana, Kumar, additional, Anbarasu, Krishnan, additional, Jeyanthi, Palanivelu, additional, Thanigaivel, Sundaram, additional, Gulothungan, Govindarajan, additional, Rajendiran, Nanmaran, additional, and Srikumar, Padmalayam Sadanandan, additional

Published
2021
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4. Contributors

Author

Ahmed M. Abdel-Azeem, Mohamed A. Abdel-Azeem, Wan Mohd Aizat, Khokon Miah Akanda, Abdelwahab A. Alsenosy, Luana Barbosa Correa, Katarina Bauerova, Rodney L. Benjamin, Prakash S. Bisen, Richard J. Bloomer, Matthew Butawan, Matthew Cheesman, Hymie Chera, Flavia M. Cicuttini, Ian Edwin Cock, Zhaoli Dai, Jonathan Daich, Harman Dhanoa, Palani Dinesh, Meenal Dixit, David T. Felson, Neda Ghamarzad Shishavan, Reza Ghiasvand, Sumit Govil, Ramesh K. Goyal, Maria das Graças Henriques, Sultana Monira Hussain, Indrani Jadhav, Rohini Karunakaran, Diyathi Tharindhi Karunaratne, Waleed F. Khalil, Viera Kuncirova, Yuan Z. Lim, Santram Lodhi, Michel Mansur Machado, Eliana Mariño, Ili Natasya Marzaimi, Justice Mbizo, Keiran H. McLeod, Maryam Miraghajani, Menachem Nagar, Mukesh Nandave, Shreesh Ojha, Anthony Okafor, Siriwan Ongchai, Vikas Pandey, Arzoo Pannu, Shalini Pareek, Kanika Patel, Dinesh Kumar Patel, G.M. Masud Parvez, Brian A. Pedersen, Pathirage Kamal Perera, Silvester Ponist, Bahram Pourghassem Gargari, Jerzy A. Przyborowski, Kilambi Pundarikakshudu, Mahaboobkhan Rasool, James L. Richards, Elaine Cruz Rosas, Yitzhak Rosen, Srikumar Padmalayam Sadanandan, Hazem M. Shaheen, Divya Shrivastava, Rajesh Shukla, Lukas Slovak, Luís Flávio Souza de Oliveira, Leauna M. Stone, Vetriselvan Subramaniyan, Paweł Sulima, Melanie A. Sutton, Jared F. Taylor, Angélica Thomaz Vieira, Gautam P. Vadnere, Maryam Vahedi, Marie van der Merwe, Marco Aurélio Ramirez Vinolo, Yuanyuan Wang, Yu Anne Yap, Puya G. Yazdi, Swan Sim Yeap, and Luísa Zuravski

Published
2019

5. Zingiber officinale: Antiinflammatory Actions and Potential Usage for Arthritic Conditions

Author

Srikumar Padmalayam Sadanandan and Rohini Karunakaran

Subjects
Leukotriene, Prostaglandin biosynthesis, Antioxidant, Traditional medicine, business.industry, medicine.medical_treatment, Research studies, Medicine, Arthritis, Zingiber officinale, business, medicine.disease
Abstract

Zingiber officinale, commonly known as ginger, has been traditionally used in the treatment of various diseases. Researchers have reported that Z. officinale possesses antiinflammatory, antioxidant, and neuroprotective properties. Z. officinale has been used effectively to treat antiinflammatory conditions and rheumatoid diseases. Clinical trials of Z. officinale have confirmed that it is effective in the treatment of swelling and the reduction of rheumatoid factors. The ameliorative effects of ginger have been related to the inhibition of the leukotriene and prostaglandin biosynthesis. Ginger is an excellent natural product and offers much promise for the treatment of arthritis. It is useful in the life-long treatment of patients, with no side effects. This chapter deals with the antiinflammatory property and the potential use of Z. officinale in the treatment of arthritis. Excerpts were picked from research studies to summarize all the findings.

Published
2019

6. Insights from the docking and molecular dynamics simulation of the Phosphopantetheinyl transferase (PptT) structural model from Mycobacterium tuberculosis.

Author

Rohini K and Srikumar PS

Abstract

A great challenge is posed to the treatment of tuberculosis due to the evolution of multidrug-resistant (MDR) and extensively drugresistant (XDR) strains of Mycobacterium tuberculosis in recent times. The complex cell envelope of the bacterium contains unusual structures of lipids which protects the bacterium from host enzymes and escape immune response. To overcome the drug resistance, targeting "drug targets" which have a critical role in growth and virulence factor is a novel approach for better tuberculosis treatment. The enzyme Phosphopantetheinyl transferase (PptT) is an attractive drug target as it is primarily involved in post translational modification of various types-I polyketide synthases and assembly of mycobactin, which is required for lipid virulence factors. Our in silico studies reported that the structural model of M.tuberculosis PptT characterizes the structure-function activity. The refinement of the model was carried out with molecular dynamics simulations and was analyzed with root mean square deviation (RMSD), and radius of gyration (Rg). This confirmed the structural behavior of PptT in dynamic system. Molecular docking with substrate coenzyme A (CoA) identified the binding pocket and key residues His93, Asp114 and Arg169 involved in PptT-CoA binding. In conclusion, our results show that the M.tuberculosis PptT model and critical CoA binding pocket initiate the inhibitor design of PptT towards tuberculosis treatment.

Published
2013
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