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633 results on '"Sportoletti, Paolo"'

1. Genetic variation in NOTCH1 is associated with overweight and obesity in Brazilian elderly

Author

Silva Barcelos, Estevão Carlos, Naslavsky, Michel Satya, Fernandes, Izadora Silveira, Scliar, Marilia Oliveira, Yamamoto, Guilherme Lopes, Wang, Jaqueline Yu Ting, Bride, Laís, de Sousa, Valdemir Pereira, Pimassoni, Lucia Helena Sagrillo, Sportoletti, Paolo, de Paula, Flavia, von Zeidler, Sandra Ventorin, Duarte, Yeda Aparecida Oliveira, Passos-Bueno, Maria Rita, Zatz, Mayana, and Errera, Flávia Imbroisi Valle

Published
2024
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2. A pro-inflammatory environment in bone marrow of Treg transplanted patients matches with graft-versus-leukemia effect

Author

Guardalupi, Francesco, Sorrentino, Carlo, Corradi, Giulia, Giancola, Raffaella, Baldoni, Stefano, Ulbar, Francesca, Fabi, Bianca, Andres Ejarque, Rosa, Timms, Jessica, Restuccia, Francesco, Santarone, Stella, Accorsi, Patrizia, Sportoletti, Paolo, De Falco, Filomena, Rosati, Emanuela, Carotti, Alessandra, Falzetti, Franca, Velardi, Andrea, Martelli, Massimo Fabrizio, Kordasti, Shahram, Pierini, Antonio, Ruggeri, Loredana, and Di Ianni, Mauro

Published
2023
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3. Other malignancies in the history of CLL: an international multicenter study conducted by ERIC, the European Research Initiative on CLL, in HARMONY

Author

Chatzikonstantinou, Thomas, Scarfò, Lydia, Karakatsoulis, Georgios, Minga, Eva, Chamou, Dimitra, Iacoboni, Gloria, Kotaskova, Jana, Demosthenous, Christos, Smolej, Lukas, Mulligan, Stephen, Alcoceba, Miguel, Al-Shemari, Salem, Aurran-Schleinitz, Thérèse, Bacchiarri, Francesca, Bellido, Mar, Bijou, Fontanet, Calleja, Anne, Medina, Angeles, Khan, Mehreen Ali, Cassin, Ramona, Chatzileontiadou, Sofia, Collado, Rosa, Christian, Amy, Davis, Zadie, Dimou, Maria, Donaldson, David, Santos, Gimena Dos, Dreta, Barbara, Efstathopoulou, Maria, El-Ashwah, Shaimaa, Enrico, Alicia, Fresa, Alberto, Galimberti, Sara, Galitzia, Andrea, García-Serra, Rocío, Gimeno, Eva, González-Gascón-y-Marín, Isabel, Gozzetti, Alessandro, Guarente, Valerio, Guieze, Romain, Gogia, Ajay, Gupta, Ritu, Harrop, Sean, Hatzimichael, Eleftheria, Herishanu, Yair, Hernández-Rivas, José-Ángel, Inchiappa, Luca, Jaksic, Ozren, Janssen, Susanne, Kalicińska, Elżbieta, Laribi, Kamel, Karakus, Volkan, Kater, Arnon P., Kho, Bonnie, Kislova, Maria, Konstantinou, Eliana, Koren-Michowitz, Maya, Kotsianidis, Ioannis, Kreitman, Robert J., Labrador, Jorge, Lad, Deepesh, Levin, Mark-David, Levy, Ilana, Longval, Thomas, Lopez-Garcia, Alberto, Marquet, Juan, Martin-Rodríguez, Lucia, Maynadié, Marc, Maslejova, Stanislava, Mayor-Bastida, Carlota, Mihaljevic, Biljana, Milosevic, Ivana, Miras, Fatima, Moia, Riccardo, Morawska, Marta, Murru, Roberta, Nath, Uttam Kumar, Navarro-Bailón, Almudena, Oliveira, Ana C., Olivieri, Jacopo, Oscier, David, Panovska-Stavridis, Irina, Papaioannou, Maria, Papajík, Tomas, Kubova, Zuzana, Phumphukhieo, Punyarat, Pierie, Cheyenne, Puiggros, Anna, Rani, Lata, Reda, Gianluigi, Rigolin, Gian Matteo, Ruchlemer, Rosa, Daniel de Deus Santos, Marcos, Schipani, Mattia, Schiwitza, Annett, Shen, Yandong, Simkovic, Martin, Smirnova, Svetlana, Abdelrahman Soliman, Dina Sameh, Spacek, Martin, Tadmor, Tamar, Tomic, Kristina, Tse, Eric, Vassilakopoulos, Theodoros, Visentin, Andrea, Vitale, Candida, von Tresckow, Julia, Vrachiolias, George, Vukovic, Vojin, Walewska, Renata, Wasik-Szczepanek, Ewa, Xu, Zhenshu, Yagci, Munci, Yañez, Lucrecia, Yassin, Mohamed, Zuchnicka, Jana, Angelopoulou, Maria, Antic, Darko, Biderman, Bella, Catherwood, Mark, Claus, Rainer, Coscia, Marta, Cuneo, Antonio, Demirkan, Fatih, Espinet, Blanca, Gaidano, Gianluca, Kalashnikova, Olga B., Laurenti, Luca, Nikitin, Eugene, Pangalis, Gerassimos A., Panagiotidis, Panagiotis, Popov, Viola Maria, Pospisilova, Sarka, Sportoletti, Paolo, Stavroyianni, Niki, Tam, Constantine, Trentin, Livio, Chatzidimitriou, Anastasia, Bosch, Francesc, Doubek, Michael, Ghia, Paolo, and Stamatopoulos, Kostas

Published
2023
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6. Prolonged XPO1 inhibition is essential for optimal antileukemic activity in NPM1-mutated AML

Author

Pianigiani, Giulia, Gagliardi, Andrea, Mezzasoma, Federica, Rocchio, Francesca, Tini, Valentina, Bigerna, Barbara, Sportoletti, Paolo, Caruso, Simona, Marra, Andrea, Peruzzi, Sara, Petito, Eleonora, Spinozzi, Giulio, Shacham, Sharon, Landesman, Yosef, Quintarelli, Concetta, Gresele, Paolo, Locatelli, Franco, Martelli, Maria Paola, Falini, Brunangelo, and Brunetti, Lorenzo

Published
2022
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7. Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL

Author

Antic, Darko, Milic, Natasa, Chatzikonstantinou, Thomas, Scarfò, Lydia, Otasevic, Vladimir, Rajovic, Nina, Allsup, David, Alonso Cabrero, Alejandro, Andres, Martin, Baile Gonzales, Monica, Capasso, Antonella, Collado, Rosa, Cordoba, Raul, Cuéllar-García, Carolina, Correa, Juan Gonzalo, De Paoli, Lorenzo, De Paolis, Maria Rosaria, Del Poeta, Giovanni, Dimou, Maria, Doubek, Michael, Efstathopoulou, Maria, El-Ashwah, Shaimaa, Enrico, Alicia, Espinet, Blanca, Farina, Lucia, Ferrari, Angela, Foglietta, Myriam, Lopez-Garcia, Alberto, García-Marco, José A., García-Serra, Rocío, Gentile, Massimo, Gimeno, Eva, da Silva, Maria Gomes, Gutwein, Odit, Hakobyan, Yervand K., Herishanu, Yair, Hernández-Rivas, José Ángel, Herold, Tobias, Itchaki, Gilad, Jaksic, Ozren, Janssens, Ann, Kalashnikova, Olga B., Kalicińska, Elżbieta, Kater, Arnon P., Kersting, Sabina, Koren-Michowitz, Maya, Labrador, Jorge, Lad, Deepesh, Laurenti, Luca, Fresa, Alberto, Levin, Mark-David, Mayor Bastida, Carlota, Malerba, Lara, Marasca, Roberto, Marchetti, Monia, Marquet, Juan, Mihaljevic, Biljana, Milosevic, Ivana, Mirás, Fatima, Morawska, Marta, Motta, Marina, Munir, Talha, Murru, Roberta, Nunes, Raquel, Olivieri, Jacopo, Pavlovsky, Miguel Arturo, Piskunova, Inga, Popov, Viola Maria, Quaglia, Francesca Maria, Quaresmini, Giulia, Reda, Gianluigi, Rigolin, Gian Matteo, Shrestha, Amit, Šimkovič, Martin, Smirnova, Svetlana, Špaček, Martin, Sportoletti, Paolo, Stanca, Oana, Stavroyianni, Niki, Te Raa, Doreen, Tomic, Kristina, Tonino, Sanne, Trentin, Livio, Van Der Spek, Ellen, van Gelder, Michel, Varettoni, Marzia, Visentin, Andrea, Vitale, Candida, Vukovic, Vojin, Wasik-Szczepanek, Ewa, Wróbel, Tomasz, Segundo, Lucrecia Yáñez San, Yassin, Mohamed, Coscia, Marta, Rambaldi, Alessandro, Montserrat, Emili, Foà, Robin, Cuneo, Antonio, Carrier, Marc, Ghia, Paolo, and Stamatopoulos, Kostas

Published
2022
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8. COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study

Author

Chatzikonstantinou, Thomas, Kapetanakis, Anargyros, Scarfò, Lydia, Karakatsoulis, Georgios, Allsup, David, Cabrero, Alejandro Alonso, Andres, Martin, Antic, Darko, Baile, Mónica, Baliakas, Panagiotis, Bron, Dominique, Capasso, Antonella, Chatzileontiadou, Sofia, Cordoba, Raul, Correa, Juan-Gonzalo, Cuéllar-García, Carolina, De Paoli, Lorenzo, De Paolis, Maria Rosaria, Del Poeta, Giovanni, Demosthenous, Christos, Dimou, Maria, Donaldson, David, Doubek, Michael, Efstathopoulou, Maria, Eichhorst, Barbara, El-Ashwah, Shaimaa, Enrico, Alicia, Espinet, Blanca, Farina, Lucia, Ferrari, Angela, Foglietta, Myriam, Frederiksen, Henrik, Fürstenau, Moritz, García-Marco, José A., García-Serra, Rocío, Gentile, Massimo, Gimeno, Eva, Glenthøj, Andreas, Gomes da Silva, Maria, Gutwein, Odit, Hakobyan, Yervand K., Herishanu, Yair, Hernández-Rivas, José Ángel, Herold, Tobias, Innocenti, Idanna, Itchaki, Gilad, Jaksic, Ozren, Janssens, Ann, Kalashnikova, Оlga B., Kalicińska, Elżbieta, Karlsson, Linda Katharina, Kater, Arnon P., Kersting, Sabina, Labrador, Jorge, Lad, Deepesh, Laurenti, Luca, Levin, Mark-David, Lista, Enrico, Lopez-Garcia, Alberto, Malerba, Lara, Marasca, Roberto, Marchetti, Monia, Marquet, Juan, Mattsson, Mattias, Mauro, Francesca R., Milosevic, Ivana, Mirás, Fatima, Morawska, Marta, Motta, Marina, Munir, Talha, Murru, Roberta, Niemann, Carsten U., Rodrigues, Raquel Nunes, Olivieri, Jacopo, Orsucci, Lorella, Papaioannou, Maria, Pavlovsky, Miguel Arturo, Piskunova, Inga, Popov, Viola Maria, Quaglia, Francesca Maria, Quaresmini, Giulia, Qvist, Kristian, Reda, Gianluigi, Rigolin, Gian Matteo, Ruchlemer, Rosa, Saghumyan, Gevorg, Shrestha, Amit, Šimkovič, Martin, Špaček, Martin, Sportoletti, Paolo, Stanca, Oana, Stavroyianni, Niki, Tadmor, Tamar, Te Raa, Doreen, Tonino, Sanne H., Trentin, Livio, Van Der Spek, Ellen, van Gelder, Michel, van Kampen, Roel, Varettoni, Marzia, Visentin, Andrea, Vitale, Candida, Wasik-Szczepanek, Ewa, Wróbel, Tomasz, San Segundo, Lucrecia Yáñez, Yassin, Mohamed, Coscia, Marta, Rambaldi, Alessandro, Montserrat, Emili, Foà, Robin, Cuneo, Antonio, Stamatopoulos, Kostas, and Ghia, Paolo

Published
2021
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10. Do age, fitness, and concomitant medications influence management and outcomes of patients with CLL treated with ibrutinib?

Author

Tedeschi, Alessandra, Frustaci, Anna Maria, Mauro, Francesca Romana, Chiarenza, Annalisa, Coscia, Marta, Ciolli, Stefania, Reda, Gianluigi, Laurenti, Luca, Varettoni, Marzia, Murru, Roberta, Baratè, Claudia, Sportoletti, Paolo, Greco, Antonino, Borella, Chiara, Rossi, Valentina, Deodato, Marina, Biagi, Annalisa, Zamprogna, Giulia, Pelle, Angelo Curto, Lapietra, Gianfranco, Vitale, Candida, Morelli, Francesca, Cassin, Ramona, Fresa, Alberto, Cavalloni, Chiara, Postorino, Massimiliano, Ielo, Claudia, Cairoli, Roberto, Di Raimondo, Francesco, Montillo, Marco, and Del Poeta, Giovanni

Published
2021
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11. Real-World Outcome of Treatment with Single-Agent Ibrutinib in Italian Patients with Chronic Lymphocytic Leukemia: Final Results of the EVIdeNCE Study

Author

Mauro, Francesca Romana, primary, Scalzulli, Potito Rosario, additional, Scarfò, Lydia, additional, Minoia, Carla, additional, Murru, Roberta, additional, Sportoletti, Paolo, additional, Frigeri, Ferdinando, additional, Albano, Francesco, additional, Di Renzo, Nicola, additional, Sanna, Alessandro, additional, Laurenti, Luca, additional, Massaia, Massimo, additional, Cassin, Ramona, additional, Coscia, Marta, additional, Patti, Caterina, additional, Pennese, Elsa, additional, Tafuri, Agostino, additional, Chiarenza, Annalisa, additional, Galieni, Piero, additional, Perbellini, Omar, additional, Selleri, Carmine, additional, Califano, Catello, additional, Ferrara, Felicetto, additional, Cuneo, Antonio, additional, Murineddu, Marco, additional, Palumbo, Gaetano, additional, Scortechini, Ilaria, additional, Tedeschi, Alessandra, additional, Trentin, Livio, additional, Varettoni, Marzia, additional, Pane, Fabrizio, additional, Liberati, Anna Marina, additional, Merli, Francesco, additional, Morello, Lucia, additional, Musuraca, Gerardo, additional, Tani, Monica, additional, Ibatici, Adalberto, additional, Regazzoni, Giulia, additional, Di Candia, Michele, additional, Palma, Maria, additional, Arienti, Danilo, additional, and Molica, Stefano, additional

Published
2024
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13. Ibrutinib as first line therapy in chronic lymphocytic leukemia patients over 80 years old: A retrospective real‐life multicenter Italian cohort

Author

Martino, Enrica Antonia, primary, Mauro, Francesca Romana, additional, Reda, Gianluigi, additional, Laurenti, Luca, additional, Visentin, Andrea, additional, Frustaci, Annamaria, additional, Vigna, Ernesto, additional, Pepe, Sara, additional, Catania, Gioacchino, additional, Loseto, Giacomo, additional, Murru, Roberta, additional, Chiarenza, Annalisa, additional, Sportoletti, Paolo, additional, Del Principe, Maria Ilaria, additional, Laureana, Roberta, additional, Coscia, Marta, additional, Galimberti, Sara, additional, Ferretti, Eleonora, additional, Zucchetto, Antonella, additional, Bomben, Riccardo, additional, Polesel, Jerry, additional, Tedeschi, Alessandra, additional, Rossi, Davide, additional, Trentin, Livio, additional, Neri, Antonino, additional, Morabito, Fortunato, additional, Gattei, Valter, additional, and Gentile, Massimo, additional

Published
2024
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14. Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML

Author

Gionfriddo, Ilaria, Brunetti, Lorenzo, Mezzasoma, Federica, Milano, Francesca, Cardinali, Valeria, Ranieri, Roberta, Venanzi, Alessandra, Pierangeli, Sara, Vetro, Calogero, Spinozzi, Giulio, Dorillo, Erica, Wu, Hsin Chieh, Berthier, Caroline, Ciurnelli, Raffaella, Griffin, Melanie J., Jennings, Claire E., Tiacci, Enrico, Sportoletti, Paolo, Falzetti, Franca, de Thé, Hugues, Veal, Gareth J., Martelli, Maria Paola, and Falini, Brunangelo

Published
2021
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15. NOTCH1 inhibition prevents GvHD and maintains GvL effect in murine models

Author

Baldoni, Stefano, Ruggeri, Loredana, Del Papa, Beatrice, Sorcini, Daniele, Guardalupi, Francesco, Ulbar, Francesca, Marra, Andrea, Dorillo, Erica, Stella, Arianna, Giancola, Raffaella, Fabi, Bianca, Sola, Rosaria, Ciardelli, Sara, De Falco, Filomena, Rompietti, Chiara, Adamo, Francesco Maria, Rosati, Emanuela, Pierini, Antonio, Sorrentino, Carlo, Sportoletti, Paolo, and Di Ianni, Mauro

Published
2021
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16. Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

Author

Sportoletti, Paolo, Sorcini, Daniele, Guzman, Anna G., Reyes, Jaime M., Stella, Arianna, Marra, Andrea, Sartori, Sara, Brunetti, Lorenzo, Rossi, Roberta, Papa, Beatrice Del, Adamo, Francesco Maria, Pianigiani, Giulia, Betti, Camilla, Scialdone, Annarita, Guarente, Valerio, Spinozzi, Giulio, Tini, Valentina, Martelli, Maria Paola, Goodell, Margaret A., and Falini, Brunangelo

Published
2021
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17. Identification of an Epi-metabolic dependency on EHMT2/G9a in T-cell acute lymphoblastic leukemia

Author

Montanaro, Anna, Kitara, Samuel, Cerretani, Elisa, Marchesini, Matteo, Rompietti, Chiara, Pagliaro, Luca, Gherli, Andrea, Su, Angela, Minchillo, Maria Laura, Caputi, Mariafrancesca, Fioretzaki, Rodanthi, Lorusso, Bruno, Ross, Linda, Alexe, Gabriela, Masselli, Elena, Marozzi, Marina, Rizzi, Federica Maria Angela, La Starza, Roberta, Mecucci, Cristina, Xiong, Yan, Jin, Jian, Falco, Angela, Knoechel, Birgit, Aversa, Franco, Candini, Olivia, Quaini, Federico, Sportoletti, Paolo, Stegmaier, Kimberly, and Roti, Giovanni

Published
2022
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18. Survival risk score for real-life relapsed/refractory chronic lymphocytic leukemia patients receiving ibrutinib. A campus CLL study

Author

Gentile, Massimo, Morabito, Fortunato, Del Poeta, Giovanni, Mauro, Francesca Romana, Reda, Gianluigi, Sportoletti, Paolo, Laurenti, Luca, Coscia, Marta, Herishanu, Yair, Recchia, Anna Grazia, Varettoni, Marzia, Murru, Roberta, Chiarenza, Annalisa, Condoluci, Adalgisa, Moia, Riccardo, Pietrasanta, Daniela, Loseto, Giacomo, Consoli, Ugo, Scortechini, Ilaria, Rossi, Francesca Maria, Zucchetto, Antonella, Fraticelli, Vincenzo, Vigna, Ernesto, Botta, Cirino, Tripepi, Giovanni, Arrigo, Graziella D’, Rago, Angela, Angeletti, Ilaria, Biagi, Annalisa, Del Giudice, Ilaria, Bomben, Riccardo, Rigolin, Gian Matteo, Rossi, Davide, Di Raimondo, Francesco, Gaidano, Gianluca, Polliack, Aaron, Cuneo, Antonio, Foà, Robin, and Gattei, Valter

Published
2021
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19. Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

Author

Marchesini, Matteo, Gherli, Andrea, Montanaro, Anna, Patrizi, Laura, Sorrentino, Claudia, Pagliaro, Luca, Rompietti, Chiara, Kitara, Samuel, Heit, Sabine, Olesen, Claus E., Møller, Jesper V., Savi, Monia, Bocchi, Leonardo, Vilella, Rocchina, Rizzi, Federica, Baglione, Marilena, Rastelli, Giorgia, Loiacono, Caterina, La Starza, Roberta, Mecucci, Cristina, Stegmaier, Kimberly, Aversa, Franco, Stilli, Donatella, Lund Winther, Anne-Marie, Sportoletti, Paolo, Bublitz, Maike, Dalby-Brown, William, and Roti, Giovanni

Published
2020
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20. Chronic Obstructive Pulmonary Disease and Previous Infections Have Impact on Infectious Complications in Patients with Chronic Lymphocytic Leukemia Treated with Venetoclax: A Multicentre Seifem Study

Author

Autore, Francesco, primary, Visentin, Andrea, additional, Deodato, Marina, additional, Vitale, Candida, additional, Galli, Eugenio, additional, Fresa, Alberto, additional, Fazzi, Rita, additional, Sanna, Alessandro, additional, Olivieri, Jacopo, additional, Scortechini, Ilaria, additional, Del Principe, Maria Ilaria, additional, Sportoletti, Paolo, additional, Schiattone, Luana, additional, Maschio, Nilla, additional, Facchinelli, Davide, additional, Coscia, Marta, additional, Tedeschi, Alessandra, additional, Trentin, Livio, additional, Innocenti, Idanna, additional, Candoni, Anna, additional, Busca, Alessandro, additional, Pagano, Livio, additional, and Laurenti, Luca, additional

Published
2023
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21. COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

Author

Scarfò, Lydia, Chatzikonstantinou, Thomas, Rigolin, Gian Matteo, Quaresmini, Giulia, Motta, Marina, Vitale, Candida, Garcia-Marco, Jose Antonio, Hernández-Rivas, José Ángel, Mirás, Fatima, Baile, Mónica, Marquet, Juan, Niemann, Carsten U., Reda, Gianluigi, Munir, Talha, Gimeno, Eva, Marchetti, Monia, Quaglia, Francesca Maria, Varettoni, Marzia, Delgado, Julio, Iyengar, Sunil, Janssens, Ann, Marasca, Roberto, Ferrari, Angela, Cuéllar-García, Carolina, Itchaki, Gilad, Špaček, Martin, De Paoli, Lorenzo, Laurenti, Luca, Levin, Mark-David, Lista, Enrico, Mauro, Francesca R., Šimkovič, Martin, Van Der Spek, Ellen, Vandenberghe, Elisabeth, Trentin, Livio, Wasik-Szczepanek, Ewa, Ruchlemer, Rosa, Bron, Dominique, De Paolis, Maria Rosaria, Del Poeta, Giovanni, Farina, Lucia, Foglietta, Myriam, Gentile, Massimo, Herishanu, Yair, Herold, Tobias, Jaksic, Ozren, Kater, Arnon P., Kersting, Sabina, Malerba, Lara, Orsucci, Lorella, Popov, Viola Maria, Sportoletti, Paolo, Yassin, Mohamed, Pocali, Barbara, Barna, Gabor, Chiarenza, Annalisa, dos Santos, Gimena, Nikitin, Eugene, Andres, Martin, Dimou, Maria, Doubek, Michael, Enrico, Alicia, Hakobyan, Yervand, Kalashnikova, Olga, Ortiz Pareja, Macarena, Papaioannou, Maria, Rossi, Davide, Shah, Nimish, Shrestha, Amit, Stanca, Oana, Stavroyianni, Niki, Strugov, Vladimir, Tam, Constantine, Zdrenghea, Mihnea, Coscia, Marta, Stamatopoulos, Kostas, Rossi, Giuseppe, Rambaldi, Alessandro, Montserrat, Emili’, Foà, Robin, Cuneo, Antonio, and Ghia, Paolo

Published
2020
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22. Germline NPM1 mutations lead to altered rRNA 2′-O-methylation and cause dyskeratosis congenita

Author

Nachmani, Daphna, Bothmer, Anne H., Grisendi, Silvia, Mele, Aldo, Bothmer, Dietmar, Lee, Jonathan D., Monteleone, Emanuele, Cheng, Ke, Zhang, Yang, Bester, Assaf C., Guzzetti, Alison, Mitchell, Caitlin A., Mendez, Lourdes M., Pozdnyakova, Olga, Sportoletti, Paolo, Martelli, Maria-Paola, Vulliamy, Tom J., Safra, Modi, Schwartz, Schraga, Luzzatto, Lucio, Bluteau, Olivier, Soulier, Jean, Darnell, Robert B., Falini, Brunangelo, Dokal, Inderjeet, Ito, Keisuke, Clohessy, John G., and Pandolfi, Pier Paolo

Published
2019
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23. Efficacy of front-line ibrutinib versus fludarabine, cyclophosphamide and rituximab (FCR) in patients with CLL. A retrospective multicenter 'real-world' study

Author

Levi, Shai, Bronstein, Yotam, Goldschmidt, Neta, Morabito, Fortunato, Ziv-Baran, Tomer, Del Poeta, Giovanni, Bairey, Osnat, Del Principe, Maria Ilaria, Fineman, Riva, Mauro, Francesca Romana, Gutwein, Odit, Reda, Gianluigi, Ruchlemer, Rosa, Sportoletti, Paolo, Laurenti, Luca, Shvidel, Lev, Coscia, Marta, Tadmor, Tamar, Varettoni, Marzia, Aviv, Ariel, Murru, Roberta, Braester, Andrei, Chiarenza, Annalisa, Visentin, Andrea, Pietrasanta, Daniela, Loseto, Giacomo, Zucchetto, Antonella, Bomben, Riccardo, Olivieri, Jacopo, Neri, Antonio, Rossi, Davide, Gaidano, Gianluca, Trentin, Livio, Foà, Robin, Cuneo, Antonio, Perry, Chava, Gattei, Valter, Gentile, Massimo, and Herishanu, Yair

Subjects
Settore MED/15
Published
2023

24. Patients' preferences for chronic lymphocytic leukemia treatment: The CHOICE study.

Author

Sportoletti, Paolo, Laurenti, Luca, Chiarenza, Annalisa, Gaidano, Gianluca, Albi, Elisa, Mauro, Francesca Romana, Trentin, Livio, Vallisa, Daniele, Pane, Fabrizio, Cuneo, Antonio, Albano, Francesco, Zamprogna, Giulia, Coscia, Marta, Gozzetti, Alessandro, Reda, Gianluigi, Caira, Morena, Finsinger, Paola, Gualberti, Giuliana, Iannella, Emilia, and Malgieri, Simona

Subjects
CHRONIC lymphocytic leukemia, PATIENT preferences, CHRONIC leukemia, COVID-19 pandemic, QUALITY of life, PROGRESSION-free survival
Abstract

Chronic lymphocytic leukemia (CLL) therapies differ in efficacy, side effects, route, frequency, and duration of administration. We assessed patient preferences for treatment attributes and evaluated associations with disease stage, treatment line, and socio‐demographic characteristics in a cross sectional, observational study conducted at 16 Italian hematology centers. Study visits occurred between February and July 2020; 401 adult patients with CLL (201 Watch and Wait (W&W), 200 treated) participated in a discrete choice experiment (DCE), composed of 8 choices between pairs of treatment profiles with different levels of 5 attributes of currently available CLL treatments (length of response, route and duration of administration, risk of side effects including diarrhea, infections, or organ damage). Health‐related quality of life was assessed with the EQ‐5D‐5L, EORTC QLQ‐C30 and QLQ CLL‐16. Previously treated patients had longer disease duration (7 vs. 5 years), higher prevalence of serious comorbidities (45.5% vs. 36.2%) and high‐risk molecular markers (unmutated IGHV 55.6% vs. 17.1%; TP53 mutation 15.2% vs. 4.0%). Health‐related quality of life scores were similar between groups. In the DCE, W&W patients rated "possible occurrence of infections" highest (relative importance [RI] = 36.2%), followed by "treatment and relevant duration" (RI = 28.0%) and "progression‐free survival (PFS)" (RI = 16.9%). Previously treated patients rated "treatment and relevant duration" highest (RI = 33.3%), followed by "possible occurrence of infections" (RI = 28.8%), "possible occurrence of organ damage" (RI = 19.4%), and "PFS" (RI = 9.8%). Concern over infection was rated highest overall; unexpectedly PFS was not among the most important criteria in either group, suggesting that the first COVID‐19 pandemic wave may have influenced patient preferences and concerns about CLL therapy options. [ABSTRACT FROM AUTHOR]

Published
2024
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25. Patients' preferences for chronic lymphocytic leukemia treatment: The CHOICE study

Author

Sportoletti, Paolo, primary, Laurenti, Luca, additional, Chiarenza, Annalisa, additional, Gaidano, Gianluca, additional, Albi, Elisa, additional, Mauro, Francesca Romana, additional, Trentin, Livio, additional, Vallisa, Daniele, additional, Pane, Fabrizio, additional, Cuneo, Antonio, additional, Albano, Francesco, additional, Zamprogna, Giulia, additional, Coscia, Marta, additional, Gozzetti, Alessandro, additional, Reda, Gianluigi, additional, Caira, Morena, additional, Finsinger, Paola, additional, Gualberti, Giuliana, additional, Iannella, Emilia, additional, Malgieri, Simona, additional, and Molica, Stefano, additional

Published
2023
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26. The evolving landscape of COVID‐19 and post‐COVID condition in patients with chronic lymphocytic leukemia: A study by ERIC, the European research initiative on CLL

Author

Visentin, Andrea, primary, Chatzikonstantinou, Thomas, additional, Scarfò, Lydia, additional, Kapetanakis, Anargyros, additional, Demosthenous, Christos, additional, Karakatsoulis, Georgios, additional, Minga, Eva, additional, Chamou, Dimitra, additional, Allsup, David, additional, Cabrero, Alejandro Alonso, additional, Andres, Martin, additional, Antic, Darko, additional, Baile, Mónica, additional, Baliakas, Panagiotis, additional, Besikli‐Dimou, Sotiria, additional, Bron, Dominique, additional, Chatzileontiadou, Sofia, additional, Cordoba, Raul, additional, Correa, Juan‐Gonzalo, additional, Cuéllar‐García, Carolina, additional, De Paoli, Lorenzo, additional, De Paolis, Maria Rosaria, additional, Delgado, Julio, additional, Dimou, Maria, additional, Donaldson, David, additional, Catherwood, Mark, additional, Doubek, Michael, additional, Efstathopoulou, Maria, additional, Eichhorst, Barbara, additional, Elashwah, Salma, additional, Enrico, Alicia, additional, Espinet, Blanca, additional, Farina, Lucia, additional, Ferrari, Angela, additional, Foglietta, Myriam, additional, Frederiksen, Henrik, additional, Fürstenau, Moritz, additional, García‐Marco, José A., additional, García‐Serra, Rocío, additional, Collado, Rosa, additional, Gentile, Massimo, additional, Gimeno, Eva, additional, Glenthøj, Andreas, additional, da Silva, Maria Gomes, additional, Hakobyan, Yervand K., additional, Herishanu, Yair, additional, Hernández‐Rivas, José Ángel, additional, Herold, Tobias, additional, Innocenti, Idanna, additional, Itchaki, Gilad, additional, Jaksic, Ozren, additional, Janssens, Ann, additional, Kalashnikova, Оlga B., additional, Kalicińska, Elżbieta, additional, Kater, Arnon P., additional, Kersting, Sabina, additional, Labrador, Jorge, additional, Lad, Deepesh, additional, Laurenti, Luca, additional, Levin, Mark‐David, additional, Lista, Enrico, additional, Lopez‐Garcia, Alberto, additional, Malerba, Lara, additional, Marasca, Roberto, additional, Marchetti, Monia, additional, Marquet, Juan, additional, Mattsson, Mattias, additional, Mauro, Francesca R., additional, Morawska, Marta, additional, Motta, Marina, additional, Munir, Talha, additional, Murru, Roberta, additional, Niemann, Carsten U., additional, Rodrigues, Raquel Nunes, additional, Olivieri, Jacopo, additional, Orsucci, Lorella, additional, Papaioannou, Maria, additional, Pavlovsky, Miguel Arturo, additional, Piskunova, Inga, additional, Popov, Viola Maria, additional, Quaglia, Francesca Maria, additional, Quaresmini, Giulia, additional, Qvist, Kristian, additional, Rigolin, Gian Matteo, additional, Ruchlemer, Rosa, additional, Šimkovič, Martin, additional, Špaček, Martin, additional, Sportoletti, Paolo, additional, Stanca, Oana, additional, Tadmor, Tamar, additional, Capasso, Antonella, additional, Del Poeta, Giovanni, additional, Gutwein, Odit, additional, Karlsson, Linda Katharina, additional, Milosevic, Ivana, additional, Mirás, Fatima, additional, Reda, Gianluigi, additional, Saghumyan, Gevorg, additional, Shrestha, Amit, additional, Te Raa, Doreen, additional, Tonino, Sanne H., additional, Van Der Spek, Ellen, additional, van Gelder, Michel, additional, van Kampen, Roel, additional, Wasik‐Szczepanek, Ewa, additional, Wróbel, Tomasz, additional, Segundo, Lucrecia Yáñez San, additional, Yassin, Mohamed, additional, Pocali, Barbara, additional, Vandenberghe, Elisabeth, additional, Iyengar, Sunil, additional, Varettoni, Marzia, additional, Vitale, Candida, additional, Coscia, Marta, additional, Rambaldi, Alessandro, additional, Montserrat, Emili, additional, Cuneo, Antonio, additional, Stavroyianni, Niki, additional, Trentin, Livio, additional, Stamatopoulos, Kostas, additional, and Ghia, Paolo, additional

Published
2023
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27. NOTCH1-mutated chronic lymphocytic leukemia displays high endoplasmic reticulum stress response with druggable potential

Author

Silva Barcelos, Estevão Carlos, primary, Rompietti, Chiara, additional, Adamo, Francesco Maria, additional, Dorillo, Erica, additional, De Falco, Filomena, additional, Del Papa, Beatrice, additional, Baldoni, Stefano, additional, Nogarotto, Manuel, additional, Esposito, Angela, additional, Capoccia, Silvia, additional, Geraci, Clelia, additional, Sorcini, Daniele, additional, Stella, Arianna, additional, Arcaleni, Roberta, additional, Tini, Valentina, additional, Imbroisi Valle Errera, Flávia, additional, Rosati, Emanuela, additional, and Sportoletti, Paolo, additional

Published
2023
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28. XPO1 mutations identify early‐stage CLL characterized by shorter time to first treatment and enhanced BCR signalling

Author

Moia, Riccardo, primary, Terzi di Bergamo, Lodovico, additional, Talotta, Donatella, additional, Bomben, Riccardo, additional, Forestieri, Gabriela, additional, Spina, Valeria, additional, Bruscaggin, Alessio, additional, Cosentino, Chiara, additional, Almasri, Mohammad, additional, Dondolin, Riccardo, additional, Bittolo, Tamara, additional, Zucchetto, Antonella, additional, Baldoni, Stefano, additional, Del Giudice, Ilaria, additional, Mauro, Francesca Romana, additional, Maffei, Rossana, additional, Chiarenza, Annalisa, additional, Tafuri, Agostino, additional, Laureana, Roberta, additional, Del Principe, Maria Ilaria, additional, Zaja, Francesco, additional, D'Arena, Giovanni, additional, Olivieri, Jacopo, additional, Rasi, Silvia, additional, Mahmoud, Abdurraouf, additional, Al Essa, Wael, additional, Awikeh, Bassel, additional, Kogila, Sreekar, additional, Bellia, Matteo, additional, Mouhssine, Samir, additional, Sportoletti, Paolo, additional, Marasca, Roberto, additional, Scarfò, Lydia, additional, Ghia, Paolo, additional, Gattei, Valter, additional, Foà, Robin, additional, Rossi, Davide, additional, and Gaidano, Gianluca, additional

Published
2023
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29. P1509: CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND PREVIOUS INFECTIONS HAD IMPACT ON INFECTIOUS COMPLICATIONS IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA TREATED WITH VENETOCLAX: A MULTICENTRE SEIFEM STUDY

Author

Autore, Francesco, primary, Visentin, Andrea, additional, Deodato, Marina, additional, Vitale, Candida, additional, Galli, Eugenio, additional, Fresa, Alberto, additional, Fazzi, Rita, additional, Sanna, Alessandro, additional, Olivieri, Jacopo, additional, Scortechini, Ilaria, additional, Principe, Maria Ilaria DEL, additional, Sportoletti, Paolo, additional, Schiattone, Luana, additional, Maschio, Nilla, additional, Facchinelli, Davide, additional, Coscia, Marta, additional, Tedeschi, Alessandra, additional, Trentin, Livio, additional, Innocenti, Idanna, additional, Candoni, Anna, additional, Busca, Alessandro, additional, Pagano, Livio, additional, and Laurenti, Luca, additional

Published
2023
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30. P686: REAL-WORLD EFFICACY PROFILE OF ASCIMINIB IN AN ITALIAN, MULTI-RESISTANT CHRONIC-PHASE CHRONIC MYELOID LEUKEMIA (CP-CML) PATIENT POPULATION

Author

Breccia, Massimo, primary, Russo Rossi, Antonella, additional, Giai, Valentina, additional, Martino, Bruno, additional, Fava, Carmen, additional, Annunziata, Mario, additional, Abruzzese, Elisabetta, additional, Binotto, Gianni, additional, Baratè, Claudia, additional, Pio Nardozza, Aurelio, additional, Misto, Alessandra, additional, Coco, Paola, additional, Calafiore, Valeria, additional, Cristina Carraro, Maria, additional, Cattina, Federica, additional, Cavazzini, Francesco, additional, Teresa Corsetti, Maria, additional, Crucitti, Lara, additional, Crugnola, Monica, additional, Ditonno, Paolo, additional, DI Veroli, Ambra, additional, Ermacora, Anna, additional, Ferrara, Felicetto, additional, Genua, Angelo, additional, Gozzini, Antonella, additional, Impera, Stefana, additional, Iurlo, Alessandra, additional, Levato, Luciano, additional, Luciano, Luigiana, additional, Cristina Miggiano, Maria, additional, De Gobbi, Marco, additional, Santoro, Marco, additional, Scappini, Barbara, additional, Rita Scortechini, Anna, additional, Patriarca, Andrea, additional, Rosati, Serena, additional, Russo, Sabina, additional, Sancetta, Rosaria, additional, Sanpaolo, Grazia, additional, Maria Santeramo, Teresa, additional, Sibilla, Silvia, additional, Sorà, Federica, additional, Sportoletti, Paolo, additional, Stagno, Fabio, additional, Trabacchi, Elena, additional, and Castagnetti, Fausto, additional

Published
2023
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31. P1038: TL-895, A FIRST-IN-CLASS, COVALENT BRUTON TYROSINE KINASE INHIBITOR (BTKI) FOR THE TREATMENT OF MYELOFIBROSIS (MF) PATIENTS (PTS) WITH SEVERE THROMBOCYTOPENIA (PLATELETS (PLTS) <50 K/UL)

Author

Loschi, Michael, primary, Rejto, Laszlo, additional, Chuah, Hun, additional, Caramella, Marianna, additional, Hernández Rivas, Jesus, additional, Sportoletti, Paolo, additional, Dubruille, Viviane, additional, Bellesso, Marcelo, additional, Gröpper, Stefanie, additional, Crodel, Carl, additional, Qamoos, Hope, additional, Socotch, Ashley, additional, Huang, Zhuying, additional, Wall, Sarah, additional, Mcgreivy, Jesse, additional, Rothbaum, Wayne P., additional, Verstovsek, Srdan, additional, and Palandri, Francesca, additional

Published
2023
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32. P597: XPO1 MUTATIONS IDENTIFY EARLY STAGE CLL CHARACTERIZED BY SHORTER TIME TO FIRST TREATMENT AND ENHANCED BCR SIGNALING

Author

Talotta, Donatella, primary, Moia, Riccardo, additional, Terzi DI Bergamo, Lodovico, additional, Bomben, Riccardo, additional, Forestieri, Gabriela, additional, Spina, Valeria, additional, Bruscaggin, Alessio, additional, Cosentino, Chiara, additional, Almasri, Mohammad, additional, Dondolin, Riccardo, additional, Bittolo, Tamara, additional, Zucchetto, Antonella, additional, Baldoni, Stefano, additional, Del Giudice, Ilaria, additional, Romana Mauro, Francesca, additional, Maffei, Rossana, additional, Chiarenza, Annalisa, additional, Tafuri, Agostino, additional, Laureana, Roberta, additional, Ilaria Del Principe, Maria, additional, Zaja, Francesco, additional, D’arena, Giovanni, additional, Olivieri, Jacopo, additional, Rasi, Silvia, additional, Mahmoud, Abdurraouf, additional, Al Essa, Wael, additional, Awikeh, Bassel, additional, Kogila, Sreekar, additional, Bellia, Matteo, additional, Mouhssine, Samir, additional, Sportoletti, Paolo, additional, Marasca, Roberto, additional, Scarfò, Lydia, additional, Ghia, Paolo, additional, Gattei, Valter, additional, Foà, Robin, additional, Rossi, Davide, additional, and Gaidano, Gianluca, additional

Published
2023
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33. S149: OTHER MALIGNANCIES IN THE HISTORY OF CLL: THE FINAL ANALYSIS OF THE INTERNATIONAL MULTICENTER STUDY CONDUCTED BY ERIC, IN HARMONY.

Author

Chatzikonstantinou, Thomas, primary, Scarfò, Lydia, additional, Karakatsoulis, Georgios, additional, Minga, Eva, additional, Chamou, Dimitra, additional, Iacoboni, Gloria, additional, Kotaskova, Jana, additional, Demosthenous, Christos, additional, Alcoceba, Miguel, additional, Al-Shemari, Salem, additional, Aurran-Schleinitz, Thérèse, additional, Bacchiarri, Francesca, additional, Bellido, Mar, additional, Bijou, Fontanet, additional, Calleja, Anne, additional, Medina, Angeles, additional, Khan, Mehreen Ali, additional, Cassin, Ramona, additional, Chatzileontiadou, Sofia, additional, Collado, Rosa, additional, Davis, Zadie, additional, Dimou, Maria, additional, Donaldson, David, additional, Santos, Gimena Dos, additional, Dreta, Barbara, additional, Efstathopoulou, Maria, additional, El-Ashwah, Shaimaa, additional, Enrico, Alicia, additional, Fresa, Alberto, additional, Galimberti, Sara, additional, Galitzia, Andrea, additional, García-Serra, Rocío, additional, Gimeno, Eva, additional, González-Gascón-Y-Marín, Isabel, additional, Gozzetti, Alessandro, additional, Guarente, Valerio, additional, Guieze, Romain, additional, Gogia, Ajay, additional, Gupta, Ritu, additional, Harrop, Sean, additional, Hatzimichael, Eleftheria, additional, Herishanu, Yair, additional, Hernández-Rivas, José-Ángel, additional, Inchiappa, Luca, additional, Jaksic, Ozren, additional, Janssen, Susanne, additional, Kalicińska, Elżbieta, additional, Kamel, Laribi, additional, Karakus, Volkan, additional, Kater, Arnon P, additional, Kho, Bonnie, additional, Kislova, Maria, additional, Konstantinou, Εliana, additional, Koren-Michowitz, Maya, additional, Kotsianidis, Ioannis, additional, Kreitman, Robert J, additional, Labrador, Jorge, additional, Lad, Deepesh, additional, Levin, Mark-David, additional, Levy, Ilana, additional, Longval, Thomas, additional, Lopez-Garcia, Alberto, additional, Marquet, Juan, additional, Maynadié, Marc, additional, Maslejova, Stanislava, additional, Mayor-Bastida, Carlota, additional, Mihaljevic, Biljana, additional, Milosevic, Ivana, additional, Miras, Fatima, additional, Moia, Riccardo, additional, Morawska, Marta, additional, Murru, Roberta, additional, Nath, Uttam Kumar, additional, Navarro-Bailón, Almudena, additional, Oliveira, Ana C., additional, Olivieri, Jacopo, additional, Oscier, David, additional, Panovska-Stavridis, Irina, additional, Papaioannou, Maria, additional, Papajík, Tomas, additional, Phumphukhieo, Punyarat, additional, Pierie, Cheyenne, additional, Puiggros, Anna, additional, Rani, Lata, additional, Reda, Gianluigi, additional, Rigolin, Gian Matteo, additional, Ronson, Aharon, additional, Ruchlemer, Rosa, additional, de Deus Santos, Marcos Daniel, additional, Schipani, Mattia, additional, Schiwitza, Annett, additional, Shen, Yandong, additional, Simkovic, Martin, additional, Smirnova, Svetlana, additional, Sameh Abdelrahman Soliman, Dina, additional, Spacek, Martin, additional, Tadmor, Tamar, additional, Tomic, Kristina, additional, Tse, Eric, additional, Vassilakopoulos, Theodoros, additional, Visentin, Andrea, additional, Vitale, Candida, additional, Tresckow, Julia von, additional, Vrachiolias, George, additional, Vukovic, Vojin, additional, Walewska, Renata, additional, Wasik-Szczepanek, Ewa, additional, Xu, Zhenshu, additional, Yagci, Munci, additional, Yañez, Lucrecia, additional, Yassin, Mohamed, additional, Zuchnicka, Jana, additional, Angelopoulou, Maria, additional, Antic, Darko, additional, Biderman, Bella, additional, Catherwood, Mark, additional, Claus, Rainer, additional, Coscia, Marta, additional, Cuneo, Antonio, additional, Demirkan, Fatih, additional, Espinet, Blanca, additional, Gaidano, Gianluca, additional, Kalashnikova, Olga, additional, Laurenti, Luca, additional, Nikitin, Eugene, additional, Pangalis, Gerassimos A., additional, Panagiotidis, Panagiotis, additional, Mulligan, Stephen, additional, Popov, Viola Maria, additional, Pospisilova, Sarka, additional, Smolej, Lukas, additional, Sportoletti, Paolo, additional, Stavroyianni, Niki, additional, Tam, Constantine, additional, Trentin, Livio, additional, Chatzidimitriou, Anastasia, additional, Bosch, Francesc, additional, Doubek, Michael, additional, Ghia, Paolo, additional, and Stamatopoulos, Kostas, additional

Published
2023
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34. PB1942: PARTIAL RESPONSE WITH LYMPHOCYTOSIS (PR-L) IS NOT APPLICABLE FOR ACALABRUTINIB. AN ITALIAN MULTICENTER EXPERIENCE OF REAL LIFE.

Author

Innocenti, Idanna, primary, Mosca, Antonio, additional, Tomasso, Annamaria, additional, Galitzia, Andrea, additional, Scarfò, Lydia, additional, Galli, Eugenio, additional, Laureana, Roberta, additional, Benintende, Giulia, additional, Mattiello, Veronica, additional, Morelli, Francesca, additional, Chiriu, Sabrina, additional, Del Principe, Maria Ilaria, additional, Zamprogna, Giulia, additional, Gentile, Massimo, additional, Fabbri, Nicole, additional, Autore, Francesco, additional, Sportoletti, Paolo, additional, Fresa, Alberto, additional, Catania, Gioacchino, additional, Coscia, Marta, additional, Tedeschi, Alessandra, additional, Sanna, Alessandro, additional, Varettoni, Marzia, additional, Ghia, Paolo, additional, Murru, Roberta, additional, and Laurenti, Luca, additional

Published
2023
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35. Therapeutic Targeting Potential of Novel Silver Nanoparticles Coated with Anti-CD20 Antibody against Chronic Lymphocytic Leukemia

Author

Adamo, Francesco Maria, primary, Silva Barcelos, Estevao Carlos, additional, De Falco, Filomena, additional, Dorillo, Erica, additional, Rompietti, Chiara, additional, Sorcini, Daniele, additional, Stella, Arianna, additional, Del Papa, Beatrice, additional, Baldoni, Stefano, additional, Esposito, Angela, additional, Geraci, Clelia, additional, Arcaleni, Roberta, additional, Pennetta, Chiara, additional, Ragonese, Francesco, additional, Moretti, Lorenzo, additional, Mameli, Mariagrazia, additional, Di Ianni, Mauro, additional, Rosati, Emanuela, additional, Fioretti, Bernard, additional, and Sportoletti, Paolo, additional

Published
2023
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36. Venetoclax infectious risk score to identify patients with chronic lymphocytic leukemia at high infectious risk during venetoclax treatment: A multicenter SEIFEM study.

Author

Autore, Francesco, Visentin, Andrea, Deodato, Marina, Vitale, Candida, Galli, Eugenio, Fresa, Alberto, Fazzi, Rita, Sanna, Alessandro, Olivieri, Jacopo, Scortechini, Ilaria, Del Principe, Maria Ilaria, Sportoletti, Paolo, Schiattone, Luana, Maschio, Nilla, Facchinelli, Davide, Marchesi, Francesco, Coscia, Marta, Tedeschi, Alessandra, Trentin, Livio, and Innocenti, Idanna

Published
2024
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38. Clinical-Grade–Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell–Dependent Graft-versus-Leukemia Effect in Murine Models

Author

Del Papa, Beatrice, Ruggeri, Loredana, Urbani, Elena, Baldoni, Stefano, Cecchini, Debora, Zei, Tiziana, Iacucci Ostini, Roberta, Crescenzi, Barbara, Carotti, Alessandra, Pierini, Antonio, Sportoletti, Paolo, Di Bartolomeo, Paolo, Falzetti, Franca, Mecucci, Cristina, Velardi, Andrea, Martelli, Massimo F., and Di Ianni, Mauro

Published
2017
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39. Antibody Response to the SARS-CoV-2 Vaccine and COVID-19 Vulnerability during the Omicron Pandemic in Patients with CLL: Two-Year Follow-Up of a Multicenter Study

Author

Mauro, Francesca R., primary, Giannarelli, Diana, additional, Galluzzo, Clementina M., additional, Visentin, Andrea, additional, Frustaci, Anna M., additional, Sportoletti, Paolo, additional, Vitale, Candida, additional, Reda, Gianluigi, additional, Gentile, Massimo, additional, Levato, Luciano, additional, Murru, Roberta, additional, Armiento, Daniele, additional, Molinari, Maria C., additional, Proietti, Giulia, additional, Pepe, Sara, additional, De Falco, Filomena, additional, Mattiello, Veronica, additional, Barabino, Luca, additional, Amici, Roberta, additional, Coscia, Marta, additional, Tedeschi, Alessandra, additional, Girmenia, Corrado, additional, Trentin, Livio, additional, and Baroncelli, Silvia, additional

Published
2023
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40. Therapeutic targeting of chronic lymphocytic leukemia by silver nanoparticles

Author

Adamo, Francesco Maria, primary, Barcelos, Estevao Carlos Silva, additional, Falco, Filomena, additional, Dorillo, Erica, additional, Rompietti, Chiara, additional, Sorcini, Daniele, additional, Stella, Arianna, additional, Papa, Beatrice Del, additional, Baldoni, Stefano, additional, Esposito, Angela, additional, Geraci, Clelia, additional, Arcaleni, Roberta, additional, Pennetta, Chiara, additional, Ragonese, Francesco, additional, Moretti, Lorenzo, additional, Mameli, Mariagrazia, additional, Ianni, Mauro, additional, Rosati, Emanuela, additional, Fioretti, Bernard, additional, and Sportoletti, Paolo, additional

Published
2023
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41. Polatuzumab‐bendamustine‐rituximab as bridge to CD19‐directed CAR T cells in mantle cell lymphoma refractory to ibrutinib and venetoclax

Author

Perriello, Vincenzo Maria, primary, Falini, Lorenza, additional, Ruggeri, Loredana, additional, Sorcini, Daniele, additional, Ballanti, Stelvio, additional, Flenghi, Leonardo, additional, Baffa, Nicodemo, additional, Covarelli, Piero, additional, Sportoletti, Paolo, additional, Pierini, Antonio, additional, and Falini, Brunangelo, additional

Published
2023
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42. Data from Dissecting Clonal Hematopoiesis in Tissues of Patients with Classic Hodgkin Lymphoma

Author

Venanzi, Alessandra, primary, Marra, Andrea, primary, Schiavoni, Gianluca, primary, Milner, Sara G., primary, Limongello, Roberto, primary, Santi, Alessia, primary, Pettirossi, Valentina, primary, Ultimo, Simona, primary, Tasselli, Luisa, primary, Pucciarini, Alessandra, primary, Falini, Lorenza, primary, Sciabolacci, Sofia, primary, Martelli, Maria Paola, primary, Sportoletti, Paolo, primary, Ascani, Stefano, primary, Falini, Brunangelo, primary, and Tiacci, Enrico, primary

Published
2023
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43. Supplementary Tables from Dissecting Clonal Hematopoiesis in Tissues of Patients with Classic Hodgkin Lymphoma

Author

Venanzi, Alessandra, primary, Marra, Andrea, primary, Schiavoni, Gianluca, primary, Milner, Sara G., primary, Limongello, Roberto, primary, Santi, Alessia, primary, Pettirossi, Valentina, primary, Ultimo, Simona, primary, Tasselli, Luisa, primary, Pucciarini, Alessandra, primary, Falini, Lorenza, primary, Sciabolacci, Sofia, primary, Martelli, Maria Paola, primary, Sportoletti, Paolo, primary, Ascani, Stefano, primary, Falini, Brunangelo, primary, and Tiacci, Enrico, primary

Published
2023
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44. Supplementary Figures from Dissecting Clonal Hematopoiesis in Tissues of Patients with Classic Hodgkin Lymphoma

Author

Venanzi, Alessandra, primary, Marra, Andrea, primary, Schiavoni, Gianluca, primary, Milner, Sara G., primary, Limongello, Roberto, primary, Santi, Alessia, primary, Pettirossi, Valentina, primary, Ultimo, Simona, primary, Tasselli, Luisa, primary, Pucciarini, Alessandra, primary, Falini, Lorenza, primary, Sciabolacci, Sofia, primary, Martelli, Maria Paola, primary, Sportoletti, Paolo, primary, Ascani, Stefano, primary, Falini, Brunangelo, primary, and Tiacci, Enrico, primary

Published
2023
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45. Supplementary Appendix from Dissecting Clonal Hematopoiesis in Tissues of Patients with Classic Hodgkin Lymphoma

Author

Venanzi, Alessandra, primary, Marra, Andrea, primary, Schiavoni, Gianluca, primary, Milner, Sara G., primary, Limongello, Roberto, primary, Santi, Alessia, primary, Pettirossi, Valentina, primary, Ultimo, Simona, primary, Tasselli, Luisa, primary, Pucciarini, Alessandra, primary, Falini, Lorenza, primary, Sciabolacci, Sofia, primary, Martelli, Maria Paola, primary, Sportoletti, Paolo, primary, Ascani, Stefano, primary, Falini, Brunangelo, primary, and Tiacci, Enrico, primary

Published
2023
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46. Supplementary Figure Legends from A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells

Author

Guarnerio, Jlenia, primary, Riccardi, Luisa, primary, Taulli, Riccardo, primary, Maeda, Takahiro, primary, Wang, Guocan, primary, Hobbs, Robin M., primary, Song, Min Sup, primary, Sportoletti, Paolo, primary, Bernardi, Rosa, primary, Bronson, Roderick T., primary, Castillo-Martin, Mireia, primary, Cordon-Cardo, Carlos, primary, Lunardi, Andrea, primary, and Pandolfi, Pier Paolo, primary

Published
2023
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47. Supplementary Figures S1 - S5 from A Genetic Platform to Model Sarcomagenesis from Primary Adult Mesenchymal Stem Cells

Author

Guarnerio, Jlenia, primary, Riccardi, Luisa, primary, Taulli, Riccardo, primary, Maeda, Takahiro, primary, Wang, Guocan, primary, Hobbs, Robin M., primary, Song, Min Sup, primary, Sportoletti, Paolo, primary, Bernardi, Rosa, primary, Bronson, Roderick T., primary, Castillo-Martin, Mireia, primary, Cordon-Cardo, Carlos, primary, Lunardi, Andrea, primary, and Pandolfi, Pier Paolo, primary

Published
2023
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48. COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study

Author

Chatzikonstantinou, Thomas, Kapetanakis, Anargyros, Scarfò, Lydia, Karakatsoulis, Georgios, Allsup, David, Cabrero, Alejandro Alonso, Andres, Martin, Antic, Darko, Baile, Mónica, Baliakas, Panagiotis, Bron, Dominique, Capasso, Antonella, Chatzileontiadou, Sofia, Cordoba, Raul, Correa, Juan-Gonzalo, Cuéllar-García, Carolina, De Paoli, Lorenzo, De Paolis, Maria Rosaria, Del Poeta, Giovanni, Demosthenous, Christos, Dimou, Maria, Donaldson, David, Doubek, Michael, Efstathopoulou, Maria, Eichhorst, Barbara, El-Ashwah, Shaimaa, Enrico, Alicia, Espinet, Blanca, Farina, Lucia, Ferrari, Angela, Foglietta, Myriam, Frederiksen, Henrik, Fürstenau, Moritz, García-Marco, José A., García-Serra, Rocío, Gentile, Massimo, Gimeno, Eva, Glenthøj, Andreas, Gomes da Silva, Maria, Gutwein, Odit, Hakobyan, Yervand K., Herishanu, Yair, Hernández-Rivas, José Ángel, Herold, Tobias, Innocenti, Idanna, Itchaki, Gilad, Jaksic, Ozren, Janssens, Ann, Kalashnikova, Оlga B., Kalicińska, Elżbieta, Karlsson, Linda Katharina, Kater, Arnon P., Kersting, Sabina, Labrador, Jorge, Lad, Deepesh, Laurenti, Luca, Levin, Mark-David, Lista, Enrico, Lopez-Garcia, Alberto, Malerba, Lara, Marasca, Roberto, Marchetti, Monia, Marquet, Juan, Mattsson, Mattias, Mauro, Francesca R., Milosevic, Ivana, Mirás, Fatima, Morawska, Marta, Motta, Marina, Munir, Talha, Murru, Roberta, Niemann, Carsten U., Rodrigues, Raquel Nunes, Olivieri, Jacopo, Orsucci, Lorella, Papaioannou, Maria, Pavlovsky, Miguel Arturo, Piskunova, Inga, Popov, Viola Maria, Quaglia, Francesca Maria, Quaresmini, Giulia, Qvist, Kristian, Reda, Gianluigi, Rigolin, Gian Matteo, Ruchlemer, Rosa, Saghumyan, Gevorg, Shrestha, Amit, Šimkovič, Martin, Špaček, Martin, Sportoletti, Paolo, Stanca, Oana, Stavroyianni, Niki, Tadmor, Tamar, Te Raa, Doreen, Tonino, Sanne H., Trentin, Livio, Van Der Spek, Ellen, van Gelder, Michel, van Kampen, Roel, Varettoni, Marzia, Visentin, Andrea, Vitale, Candida, Wasik-Szczepanek, Ewa, Wróbel, Tomasz, San Segundo, Lucrecia Yáñez, Yassin, Mohamed, Coscia, Marta, Rambaldi, Alessandro, Montserrat, Emili, Foà, Robin, Cuneo, Antonio, Stamatopoulos, Kostas, and Ghia, Paolo

Abstract

Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to Coronavirus disease 2019 (COVID-19) due to age, disease, and treatment-related immunosuppression. We aimed to assess risk factors of outcome and elucidate the impact of CLL-directed treatments on the course of COVID-19. We conducted a retrospective, international study, collectively including 941 patients with CLL and confirmed COVID-19. Data from the beginning of the pandemic until March 16, 2021, were collected from 91 centers. The risk factors of case fatality rate (CFR), disease severity, and overall survival (OS) were investigated. OS analysis was restricted to patients with severe COVID-19 (definition: hospitalization with need of oxygen or admission into an intensive care unit). CFR in patients with severe COVID-19 was 38.4%. OS was inferior for patients in all treatment categories compared to untreated (p< 0.001). Untreated patients had a lower risk of death (HR = 0.54, 95% CI:0.41–0.72). The risk of death was higher for older patients and those suffering from cardiac failure (HR = 1.03, 95% CI:1.02–1.04; HR = 1.79, 95% CI:1.04–3.07, respectively). Age, CLL-directed treatment, and cardiac failure were significant risk factors of OS. Untreated patients had a better chance of survival than those on treatment or recently treated.

Published
2024
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49. Validation of a survival-risk score (SRS) in relapsed/refractory CLL patients treated with idelalisib–rituximab

Author

Gentile, Massimo, Martino, Enrica Antonia, Visentin, Andrea, Coscia, Marta, Reda, Gianluigi, Sportoletti, Paolo, Mauro, Francesca Romana, Laurenti, Luca, Varettoni, Marzia, Murru, Roberta, Chiarenza, Annalisa, Vigna, Ernesto, Mendicino, Francesco, Lucia, Eugenio, Bossio, Sabrina, Recchia, Anna Grazia, Moia, Riccardo, Pietrasanta, Daniela, Loseto, Giacomo, Consoli, Ugo, Scortechini, Ilaria, Rossi, Francesca Maria, Zucchetto, Antonella, Al-Janazreh, Hamdi, Vitale, Candida, Tripepi, Giovanni, D’Arrigo, Graziella, Angeletti, Ilaria, Bomben, Riccardo, Neri, Antonino, Cutrona, Giovanna, Fronza, Gilberto, Di Raimondo, Francesco, Gaidano, Gianluca, Cuneo, Antonio, Foà, Robin, Ferrarini, Manlio, Trentin, Livio, Gattei, Valter, and Morabito, Fortunato

Published
2020
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50. Lymphadenopathy as a predictor of progression during venetoclax treatment in chronic lymphocytic leukemia. A campus chronic lymphocytic leukemia study.

Author

Autore, Francesco, Innocenti, Idanna, Reda, Gianluigi, Visentin, Andrea, Vitale, Candida, Piciocchi, Alfonso, Fresa, Alberto, Leone, Monica M. A., Farina, Lucia, Quaresmini, Giulia, Baratè, Claudia, Giordano, Annamaria, Ferrari, Angela, Angeletti, Ilaria, De Paolis, Maria Rosaria, Malerba, Lara, Chiurazzi, Federico, Loseto, Giacomo, Catania, Gioacchino, and Sportoletti, Paolo

Subjects
CHRONIC lymphocytic leukemia, VENETOCLAX, PROGRESSION-free survival, LYMPHADENITIS, LYMPHATIC metastasis, MULTIVARIATE analysis, CHRONIC leukemia
Abstract

Clinical or biological parameters useful to predict progression during treatment in real‐life setting with ibrutinib, idelalisib and venetoclax in relapsed/refractory chronic lymphocytic leukemia (CLL) are still debated. We conducted a multi‐center retrospective study on CLL patients treated with ibrutinib and/or idelalisib who were switched to venetoclax for progression or due to adverse events to identify any clinical and/or biological parameters useful to predict progression during treatment with venetoclax. Of all the 128 evaluable patients, 81 had received ibrutinib prior to switching to venetoclax, 35 had received idelalisib and 12 both. When comparing the three subgroups, we did not notice any statistical difference in terms of clinical or biological features. No variable at baseline and at different time points during the follow‐up (at 6, 12, 18 and 24 months) was found to predict progression nor to have significance for Progression Free Survival (PFS) in the ibrutinib group and in the idelalisib group and in subgroups according to the line of treatment. Analyzing the data of the venetoclax treatment, after a median follow up of 14.3 months, median PFS was not reached and estimated 3‐year PFS was 54%. Of the 128 patients treated with venetoclax, 28 (22%) experienced progressive disease. At multivariate analysis for predictive factors for progression, lymph node diameter >56.5 mm before starting treatment emerged as an independent risk factor for progression. The lymph node predictive role for progression during venetoclax treatment could be a new parameter that deserves to be investigate in future studies. [ABSTRACT FROM AUTHOR]

Published
2023
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