69 results on '"Spencer Marcantonio Camargo"'
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2. Computed tomography on lung cancer screening is useful for adjuvant comorbidity diagnosis in developing countries
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Juliane Nascimento de Mattos, Carlos Eugênio Santiago Escovar, Manuela Zereu, Adalberto Sperb Rubin, Spencer Marcantonio Camargo, Tan-Lucien Mohammed, Ricardo Sales dos Santos, Nupur Verma, Diana Penha Pereira, Erique Guedes Pinto, Tiago Machuca, Tássia Machado Medeiros, and Bruno Hochhegger
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Medicine - Abstract
Purpose The aim of this study was to analyse and quantify the prevalence of six comorbidities from lung cancer screening (LCS) on computed tomography (CT) scans of patients from developing countries. Methods For this retrospective study, low-dose CT scans (n=775) were examined from patients who underwent LCS in a tertiary hospital between 2016 and 2020. An age- and sex-matched control group was obtained for comparison (n=370). Using the software, coronary artery calcification (CAC), the skeletal muscle area, interstitial lung abnormalities, emphysema, osteoporosis and hepatic steatosis were accessed. Clinical characteristics of each participant were identified. A t-test and Chi-squared test were used to examine differences between these values. Interclass correlation coefficients (ICCs) and interobserver agreement (assessed by calculating kappa coefficients) were calculated to assess the correlation of measures interpreted by two observers. p-values
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- 2022
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3. Transplante pulmonar sem circulação extracorpórea em uma paciente com síndrome de Kartagener Lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener syndrome
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Luziélio Alves Sidney Filho, Tiago Noguchi Machuca, José de Jesus Camargo, José Carlos Felicetti, Spencer Marcantonio Camargo, Fabíola Adélia Perin, Letícia Beatriz Sanchez, and Sadi Marcelo Schio
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Diseases of the respiratory system ,RC705-779 - Published
- 2012
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4. Sobrevida de 12 anos do primeiro transplante pulmonar pediátrico intervivos do Brasil
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Tiago Noguchi Machuca, Luzielio Alves Sidney Filho, Sadi Marcelo Schio, Spencer Marcantonio Camargo, José Carlos Felicetti, and José de Jesus Peixoto Camargo
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Transplante de pulmão ,bronquiolite obliterante ,doadores vivos ,pediatria ,Pediatrics ,RJ1-570 - Abstract
OBJETIVO: Apresentar o acompanhamento a longo prazo do primeiro caso de transplante pulmonar intervivos realizado na América Latina. DESCRIÇÃO: Paciente do sexo masculino, com 12 anos de idade, portador de bronquiolite obliterante com doença pulmonar avançada. Fazia uso de oxigênio domiciliar contínuo, com dispneia aos mínimos esforços. Foi submetido a transplante pulmonar bilateral com doadores vivos. A cirurgia foi realizada utilizando os lobos inferiores esquerdo e direito de dois doadores diferentes e com grau de parentesco com o receptor. No segundo lado (direito), foi necessário emprego de circulação extracorpórea. O transplante não teve intercorrências, e o paciente foi extubado com 14 horas de pós-operatório; com 44 dias, recebeu alta hospitalar, após a resolução de complicações infecciosas, imunológicas e medicamentosas. Após 12 anos de seguimento, encontra-se com função pulmonar preservada e desempenha normalmente suas atividades. COMENTÁRIOS: O transplante pulmonar intervivos é um procedimento de alta complexidade que pode contribuir para o tratamento de algumas pneumopatias na infância. Essa população se beneficia dessa abordagem, uma vez que a disponibilidade de doadores pediátricos é muito rara, e as pneumopatias pediátricas tendem a seguir um curso imprevisível.
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- 2012
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5. Ground-glass nodules and CT-guided placement of platinum coils
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Bruno Hochhegger, Fabíola Adélia Perin, Spencer Marcantonio Camargo, Edson Marchiori, Klaus Irion, Marcos Duarte Guimarães, Jose Carlos Felicetti, and Jose Camargo
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Diseases of the respiratory system ,RC705-779 - Published
- 2014
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6. Nódulo sincrônico pulmonar e hepático em paciente com antecedente de carcinoma broncogênico: a importância da confirmação histopatológica Synchronous pulmonary and hepatic nodules in a patient with previous bronchogenic carcinoma: the relevance of histopathological confirmation
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José de Jesus Peixoto Camargo, Tiago Noguchi Machuca, Spencer Marcantonio Camargo, Sadi Marcelo Schio, and Rodrigo Moreira Bello
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Carcinoma broncogênico ,Metástase neoplásica ,Carcinoma hepatocelular ,Carcinoma, bronchogenic ,Neoplasm metastasis ,Carcinoma, hepatocellular ,Diseases of the respiratory system ,RC705-779 - Abstract
A apresentação de lesão sincrônica pulmonar e hepática em um paciente com antecedente de carcinoma broncogênico operado gera a suspeita de recidiva tumoral e indica a necessidade de re-estadiamento. Apresentamos o caso de um paciente de 71 anos submetido à lobectomia pulmonar com ressecção de pericárdio e linfadenectomia mediastinal (T3N0M0). Cinco anos após a cirurgia, detectou-se a presença de uma nova lesão pulmonar. No re-estadiamento, foi diagnosticada uma lesão sincrônica no fígado. Apesar da forte suspeita de recidiva tumoral, prosseguiu-se a investigação e uma punção hepática revelou carcinoma hepatocelular. Para esclarecer a etiologia da lesão pulmonar (hipóteses de recidiva de carcinoma brônquico ou de metástase de carcinoma hepatocelular), foi realizada uma biópsia a céu aberto, compatível com reação inflamatória crônica com focos de antracose e de calcificação distrófica. O paciente foi então submetido à ressecção hepática não-regrada com intuito curativo. Teve boa evolução, com alta no 10º dia de pós-operatório. O presente relato destaca a importância do diagnóstico histopatológico em pacientes com antecedente de carcinoma broncogênico e suspeita de recidiva. Hipóteses diagnósticas e condutas terapêuticas são discutidas.The synchronous presentation of pulmonary and hepatic nodules in a patient with previously resected bronchogenic carcinoma raises suspicion of recurrence and mandates restaging. We present the case of a 71-year-old male with a history of lobectomy with pericardial resection and mediastinal lymphadenectomy (T3N0M0). At five years after the operation, he presented with a new pulmonary lesion. Restaging detected a synchronous nodule in the liver. Despite the strong suspicion of tumor recurrence, further investigation with a percutaneous liver biopsy revealed hepatocellular carcinoma. In order to investigate the etiology of the pulmonary lesion (hypotheses of recurrent bronchial cancer and of metastatic hepatocellular carcinoma), an open lung biopsy was performed, which revealed chronic inflammatory tissue with foci of anthracosis and dystrophic calcification. The patient was submitted to a non-anatomic resection of the liver lesion. The postoperative course was uneventful, and the patient was discharged on postoperative day 10. This report highlights the relevance of the histopathological diagnosis in patients with a history of bronchogenic carcinoma and suspicion of tumor recurrence. Differential diagnoses and the treatment administered are discussed.
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- 2009
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7. Síndrome incompleto de Carney
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Lina Maria Velásquez Gomez, Frederico Barth, Gustavo Grün, Diego Cassagrande Madalosso, Fabiola Perin, Spencer Marcantonio Camargo, Jose Carlos Felicetti, and Jose de Jesus Peixoto Camargo
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síndrome de Carney ,neoplasias pulmonares ,condroma ,paraganglioma ,extra-adrenal ,tumores del estroma gastrointestinal ,Surgery ,RD1-811 - Abstract
El síndrome de Carney es una enfermedad rara, con diferentes formas de presentación, que afecta principalmente al sexo femenino y es asintomática en la mayoría de los casos. Se caracteriza por la aparición de tumores, generalmente benignos, principalmente en el pulmón, la glándula suprarrenal y el estómago; sin embargo, se pueden afectar otros órganos como el esófago. Su tratamiento es principalmente quirúrgico. Se presenta el caso de una paciente con síndrome incompleto de Carney, manejada quirúrgicamente, con excelente resultado posoperatorio. Se hace una revisión de la literatura científica actual.
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- 2015
8. Síndrome incompleto de Carney
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Lina Maria Velásquez Gomez, Frederico Barth, Gustavo Grün, Diego Cassagrande Madalosso, Fabiola Perin, Spencer Marcantonio Camargo, Jose Carlos Felicetti, and Jose de Jesus Peixoto Camargo
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Carney syndrome ,lung neoplasms ,chondroma ,paraganglioma ,extra-adrenal ,gastrointestinal stromal tumors ,Surgery ,RD1-811 - Abstract
El síndrome de Carney es una enfermedad rara, con diferentes formas de presentación, que afecta principalmente al sexo femenino y es asintomática en la mayoría de los casos. Se caracteriza por la aparición de tumores, generalmente benignos, principalmente en el pulmón, la glándula suprarrenal y el estómago; sin embargo, se pueden afectar otros órganos como el esófago. Su tratamiento es principalmente quirúrgico. Se presenta el caso de una paciente con síndrome incompleto de Carney, manejada quirúrgicamente, con excelente resultado posoperatorio. Se hace una revisión de la literatura científica actual.
9. Diretrizes para avaliação e validação do potencial doador de órgãos em morte encefálica
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Glauco Adrieno Westphal, Valter Duro Garcia, Rafael Lisboa de Souza, Cristiano Augusto Franke, Kalinca Daberkow Vieira, Viviane Renata Zaclikevis Birckholz, Miriam Cristine Machado, Eliana Régia Barbosa de Almeida, Fernando Osni Machado, Luiz Antônio da Costa Sardinha, Raquel Wanzuita, Carlos Eduardo Soares Silvado, Gerson Costa, Vera Braatz, Milton Caldeira Filho, Rodrigo Furtado, Luana Alves Tannous, André Gustavo Neves de Albuquerque, Edson Abdala, Anderson Ricardo Roman Gonçalves, Lúcio Filgueiras Pacheco-Moreira, Fernando Suparregui Dias, Rogério Fernandes, Frederico Di Giovanni, Frederico Bruzzi de Carvalho, Alfredo Fiorelli, Cassiano Teixeira, Cristiano Feijó, Spencer Marcantonio Camargo, Neymar Elias de Oliveira, André Ibrahim David, Rafael Augusto Dantas Prinz, Laura Brasil Herranz, and Joel de Andrade
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Medical emergencies. Critical care. Intensive care. First aid ,RC86-88.9 - Abstract
RESUMO O transplante de órgãos é a única alternativa para muitos pacientes portadores de algumas doenças terminais. Ao mesmo tempo, é preocupante a crescente desproporção entre a alta demanda por transplantes de órgãos e o baixo índice de transplantes efetivados. Dentre as diferentes causas que alimentam essa desproporção, estão os equívocos na identificação do potencial doador de órgãos e as contraindicações mal atribuídas pela equipe assistente. Assim, o presente documento pretende fornecer subsídios à equipe multiprofissional da terapia intensiva para o reconhecimento, a avaliação e a validação do potencial doador de órgãos.
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10. Anatomic pulmonary resection by video-assisted thoracoscopy: the Brazilian experience (VATS Brazil study)
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Ricardo Mingarini Terra, Thamara Kazantzis, Darcy Ribeiro Pinto-Filho, Spencer Marcantonio Camargo, Francisco Martins-Neto, Anderson Nassar Guimarães, Carlos Alberto Araújo, Luis Carlos Losso, Mario Claudio Ghefter, Nuno Ferreira de Lima, Antero Gomes-Neto, Flávio Brito-Filho, Rui Haddad, Maurício Guidi Saueressig, Alexandre Marcelo Rodrigues Lima, Rafael Pontes de Siqueira, Astunaldo Júnior de Macedo e Pinho, and Fernando Vannucci
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Thoracic surgery, video-assisted ,Thoracoscopy ,Pneumonectomy ,Diseases of the respiratory system ,RC705-779 - Abstract
ABSTRACT Objective: The objective of this study was to describe the results of anatomic pulmonary resections performed by video-assisted thoracoscopy in Brazil. Methods: Thoracic surgeons (members of the Brazilian Society of Thoracic Surgery) were invited, via e-mail, to participate in the study. Eighteen surgeons participated in the project by providing us with retrospective databases containing information related to anatomic pulmonary resections performed by video-assisted thoracoscopy. Demographic, surgical, and postoperative data were collected with a standardized instrument, after which they were compiled and analyzed. Results: The surgeons provided data related to a collective total of 786 patients (mean number of resections per surgeon, 43.6). However, 137 patients were excluded because some data were missing. Therefore, the study sample comprised 649 patients. The mean age of the patients was 61.7 years. Of the 649 patients, 295 (45.5%) were male. The majority-521 (89.8%)-had undergone surgery for neoplasia, which was most often classified as stage IA. The median duration of pleural drainage was 3 days, and the median hospital stay was 4 days. Of the 649 procedures evaluated, 598 (91.2%) were lobectomies. Conversion to thoracotomy was necessary in 30 cases (4.6%). Postoperative complications occurred in 124 patients (19.1%), the most common complications being pneumonia, prolonged air leaks, and atelectasis. The 30-day mortality rate was 2.0%, advanced age and diabetes being found to be predictors of mortality. Conclusions: Our analysis of this representative sample of patients undergoing pulmonary resection by video-assisted thoracoscopy in Brazil showed that the procedure is practicable and safe, as well as being comparable to those performed in other countries.
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11. Round pneumonia: a rare condition mimicking bronchogenic carcinoma. Case report and review of the literature
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José Jesus de Peixoto Camargo, Spencer Marcantonio Camargo, Tiago Noguchi Machuca, and Fabíola Adélia Perin
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Pneumonia ,Lung neoplasm ,Lung diseases ,Medical imaging ,Lung ,Medicine - Abstract
CONTEXT: Round pneumonia is a condition usually described in children, with few reports addressing adult patients. It is an oval-shaped consolidation that, due to its radiological appearance, simulates bronchogenic carcinoma. Its evolution tends to be benign, although diagnostic dilemmas have sometimes required exploratory thoracotomy. Deaths caused by this condition have even been reported. To the best of our knowledge, there have been 31 previous cases of round pneumonia in adults reported in the English and Portuguese-language literature, of which only one was completely asymptomatic. CASE REPORT: The case of a 54-year-old female patient presenting a lung mass found on routine imaging evaluation is reported. Respiratory symptoms and signs were absent, but the patient had a significant history of smoking. Her physical examination gave normal results. On chest radiographs, a mass located in the middle third of the right lung was observed. Three weeks after the initial evaluation, the patient was admitted for a complete evaluation and for staging of a pulmonary malignancy, but repeated chest radiographs showed complete resolution.
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12. Extracorporeal membrane oxygenation in an awake patient as a bridge to lung transplantation
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Spencer Marcantonio Camargo, Stephan Adamour Soder, Fabiola Adelia Perin, Douglas Zaione Nascimento, and Sadi Marcelo Schio
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Diseases of the respiratory system ,RC705-779 - Full Text
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13. PP.24 High Correlation With KRAS and PDL-1 in Lung Adenocarcinoma of a Single Institution
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Bruna Motke, Manuela Zereu, Spencer Marcantonio Camargo, Jose Felicetti, Bruna Santin, Luiza Andres, Fabiola Perin, and Stephan Soder
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Pulmonary and Respiratory Medicine ,Oncology - Published
- 2023
14. FP13.04 CHECK Lung Protocol: CT Lung Cancer Screening is Useful to Adjuvant Comorbid Diseases Diagnosis
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C.E. Escovar, M. Zereu, Bruno Hochhegger, J. De Mattos, Tan-Lucien H. Mohammed, F. Torres, Spencer Marcantonio Camargo, A. Rubin, P.A. Schulze, and Nupur Verma
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Pulmonary and Respiratory Medicine ,Protocol (science) ,Oncology ,medicine.medical_specialty ,Lung ,business.industry ,medicine.medical_treatment ,medicine.anatomical_structure ,Internal medicine ,Medicine ,business ,Adjuvant ,Lung cancer screening - Published
- 2021
15. Video-assisted thoracoscopic surgery yields better outcomes than thoracotomy for anatomical lung resection in Brazil: a propensity score-matching analysis using the Brazilian Society of Thoracic Surgery database†
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Maria Teresa Ruiz Tsukazan, Álvaro Vigo, G. Fortunato, Darcy Ribeiro Pinto Filho, Antero Gomes Neto, Ricardo Mingarini Terra, Humberto Alves de Oliveira, and Spencer Marcantonio Camargo
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Adult ,Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Lung Neoplasms ,Databases, Factual ,MORBIDADE ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,computer.software_genre ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,medicine ,Humans ,Thoracotomy ,Pneumonectomy ,Propensity Score ,Lung cancer ,Aged ,Retrospective Studies ,Database ,Thoracic Surgery, Video-Assisted ,business.industry ,Retrospective cohort study ,General Medicine ,Odds ratio ,Middle Aged ,medicine.disease ,Confidence interval ,030228 respiratory system ,Cardiothoracic surgery ,Video-assisted thoracoscopic surgery ,Propensity score matching ,Female ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,computer ,Brazil - Abstract
Objectives The use of video-assisted anatomical lung resection is increasingly widespread for lung cancer and non-neoplastic diseases, showing excellent results. Nonetheless, a comparative analysis of the benefits of this technique has yet to be conducted in Latin America, a region with a completely different case mix from the USA or Europe. The purpose of this study was to compare the outcomes of video-assisted thoracoscopic surgery (VATS) and open thoracotomy (OT) for anatomical lung resection in patients included on the Brazilian Society of Thoracic Surgery (BSTS) database. Methods Using propensity score matching, we conducted an analysis of 1355 patients who underwent anatomical lung resection (704 OT and 651 VATS) registered in the BSTS database between August 2015 and December 2016. Propensity score matching was performed using the following baseline characteristics: age at surgery, gender, comorbidities, pulmonary lung function, type of resection and cancer and non-cancer diagnosis. The propensity score-matched sample comprised a well-matched group of 890 patients. The main outcomes tested were mortality, complications and major cardiopulmonary complications based on the European Society of Thoracic Surgeons (ESTS) database definitions and terminology. Results Standardized differences of means and proportions suggested that an adequate balance had been achieved. Major cardiopulmonary complications were shown to be more frequent in patients who underwent OT (16.0% compared with 9.2% in VATS patients; odds ratio = 1.87, 95% confidence interval 1.25-2.80) and the overall complications rate was higher among patients who underwent OT (30.1% compared with 21.8% in VATS patients; odds ratio = 1.55, 95% confidence interval 1.17-2.05). No statistically significant difference in mortality rate was observed between OT (2.5%) and VATS (1.8%) (odds ratio = 1.38, 95% confidence interval 0.54-3.50). Conclusions In Brazil, the rate of complications associated with minimally invasive surgery (VATS) for anatomical lung resection is significantly lower than that of conventional OT.
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- 2017
16. P06.09 Lobectomy for Lung Cancer, What Is the Brazilian reality? Brazilian Society of Thoracic Surgeons Analysis
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L. Brand, Maria Teresa Ruiz Tsukazan, Mauricio Guidi Saueressig, Ricardo R. Terra, M. Soares, Humberto Alves de Oliveira, A. Miotto, Álvaro Vigo, S. De Sateles, G. Fortunato, and Spencer Marcantonio Camargo
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Oncology ,business.industry ,General surgery ,medicine ,Lung cancer ,medicine.disease ,business - Published
- 2021
17. Ressecção Pulmonar: Análise do Banco de Dados da Sociedade Brasileira de Cirurgia Torácica
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Leticia Leone Lauricella, G. Fortunato, Humberto Alves de Oliveira, Darcy Pinto, Maria Teresa Ruiz Tsukazan, Ricardo Mingarini Terra, and Spencer Marcantonio Camargo
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A Sociedade Brasileira de Cirurgia Torácica (SBCT) utiliza uma versão customizada da plataforma de banco de dados da Sociedade Europeia de Cirurgia Torácica (ESTS). Nesta análise, de agosto/15 a dezembro/ 15, 1.367 pacientes haviam sido registrados no banco de dados. Destes, 902 haviam sido submetidos à ressecção pulmonar anatômica (lobectomia, segmentectomia ou pneumectomia). O desfecho analisado foi morbi-mortalidade intrahospitalar.
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- 2020
18. Pulmonary rehabilitation improves survival in patients with idiopathic pulmonary fibrosis undergoing lung transplantation
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Juliessa Florian, Leticia Sanchez, Stephan Altmayer, Douglas Zaione Nascimento, Paulo José Zimermann Teixeira, Spencer Marcantonio Camargo, Fabiola Adelia Perin, José da Silva Moreira, José de Jesus Peixoto Camargo, Guilherme Watte, Sadi Marcelo Schio, and José Carlos Felicetti
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0301 basic medicine ,Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,lcsh:Medicine ,Kaplan-Meier Estimate ,Article ,Perioperative Care ,law.invention ,03 medical and health sciences ,Idiopathic pulmonary fibrosis ,0302 clinical medicine ,law ,Internal medicine ,medicine ,Lung transplantation ,Humans ,Pulmonary rehabilitation ,lcsh:Science ,Aged ,Retrospective Studies ,Mechanical ventilation ,Respiratory tract diseases ,Multidisciplinary ,Lung ,business.industry ,Proportional hazards model ,lcsh:R ,Rehabilitation ,Retrospective cohort study ,Recovery of Function ,Middle Aged ,medicine.disease ,Prognosis ,Intensive care unit ,Respiration, Artificial ,Idiopathic Pulmonary Fibrosis ,Respiratory Function Tests ,030104 developmental biology ,medicine.anatomical_structure ,Treatment Outcome ,lcsh:Q ,Female ,business ,030217 neurology & neurosurgery ,Lung Transplantation - Abstract
This study was conducted to evaluate whether a pulmonary rehabilitation program (PRP) is independently associated with survival in patients with idiopathic pulmonary fibrosis (IPF) undergoing lung transplant (LTx). This quasi-experimental study included 89 patients who underwent LTx due to IPF. Thirty-two completed all 36 sessions in a PRP while on the waiting list for LTx (PRP group), and 53 completed fewer than 36 sessions (controls). Survival after LTx was the main outcome; invasive mechanical ventilation (IMV), length of stay (LOS) in intensive care unit (ICU) and in hospital were secondary outcomes. Kaplan-Meier curves and Cox regression models were used in survival analyses. Cox regression models showed that the PRP group had a reduced 54.0% (hazard ratio = 0.464, 95% confidence interval 0.222–0.970, p = 0.041) risk of death. A lower number of patients in the PRP group required IMV for more than 24 hours after LTx (9.0% vs. 41.6% p = 0.001). This group also spent a mean of 5 days less in the ICU (p = 0.004) and 5 days less in hospital (p = 0.046). In conclusion, PRP PRP completion halved the risk of cumulative mortality in patients with IPF undergoing unilateral LTx
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- 2019
19. P41.05 Challenges of Implementing Lung Cancer Screening in Brazil: Preliminary Results of a Multicenter Group
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C.E. Escovar, R. Chiarantano, Juliana P. Franceschini, G. Szarf, Jefferson Luiz Gross, R. F. Pereira, Spencer Marcantonio Camargo, Bruno Hochhegger, P. Sarmento, M. Albuquerque, João Rocha, N. Rizvi, Rui Manuel Reis, G. Teles, Mario C.laudio Ghefter, Marcos Duarte Guimarães, Paula Barbosa, Rodrigo Caruso Chate, and E. Mauad
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Oncology ,business.industry ,Internal medicine ,Medicine ,business ,Lung cancer screening - Published
- 2021
20. Diretrizes para avaliação e validação do potencial doador de órgãos em morte encefálica
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Eliana Regia Barbosa de Almeida, Glauco Adrieno Westphal, Frederico Di Giovanni, Rafael Lisboa de Souza, André Ibrahim David, Cristiano Augusto Franke, Gerson Costa, Edson Abdala, Viviane Renata Zaclikevis Birckholz, Cassiano Teixeira, Luana Alves Tannous, Neymar Elias de Oliveira, Milton Caldeira Filho, Laura Brasil Herranz, Vera Braatz, Fernando Suparregui Dias, Miriam Cristine V Machado, André Gustavo Neves de Albuquerque, Rogério Fernandes, Lucio F. Pacheco-Moreira, Raquel Wanzuita, Rodrigo Furtado, Cristiano Feijó, Rafael Augusto Dantas Prinz, Fernando Osni Machado, Carlos Silvado, Anderson R.R. Gonçalves, Joel de Andrade, Frederico Bruzzi de Carvalho, Kalinca Daberkow Vieira, Luiz Antonio da Costa Sardinha, Alfredo Inácio Fiorelli, Spencer Marcantonio Camargo, and Valter Duro Garcia
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medicine.medical_specialty ,Brain Death ,Tissue and Organ Procurement ,030504 nursing ,business.industry ,General Medicine ,Organ Transplantation ,Critical Care and Intensive Care Medicine ,Organ transplantation ,Tissue Donors ,03 medical and health sciences ,Intensive Care Units ,0302 clinical medicine ,Intensive care ,Medicine ,Special Articles ,Humans ,030212 general & internal medicine ,0305 other medical science ,business ,Intensive care medicine - Abstract
RESUMO O transplante de órgãos é a única alternativa para muitos pacientes portadores de algumas doenças terminais. Ao mesmo tempo, é preocupante a crescente desproporção entre a alta demanda por transplantes de órgãos e o baixo índice de transplantes efetivados. Dentre as diferentes causas que alimentam essa desproporção, estão os equívocos na identificação do potencial doador de órgãos e as contraindicações mal atribuídas pela equipe assistente. Assim, o presente documento pretende fornecer subsídios à equipe multiprofissional da terapia intensiva para o reconhecimento, a avaliação e a validação do potencial doador de órgãos. ABSTRACT Organ transplantation is the only alternative for many patients with terminal diseases. The increasing disproportion between the high demand for organ transplants and the low rate of transplants actually performed is worrisome. Some of the causes of this disproportion are errors in the identification of potential organ donors and in the determination of contraindications by the attending staff. Therefore, the aim of the present document is to provide guidelines for intensive care multi-professional staffs for the recognition, assessment and acceptance of potential organ donors.
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- 2016
21. Silicone Thorax: Another Complication of Breast Prosthesis Rupture
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Bruno Hochhegger, Spencer Marcantonio Camargo, and Edson Marchiori
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Pulmonary and Respiratory Medicine ,Thorax ,Rupture ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Breast Implants ,Silicones ,General Medicine ,Prosthesis ,Surgery ,chemistry.chemical_compound ,Silicone ,chemistry ,medicine ,Humans ,Complication ,business ,Breast Implantation - Published
- 2018
22. Brazilian guidelines for the diagnosis and treatment of cystic fibrosis
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Rodrigo Abensur Athanazio, Luiz Vicente Ribeiro Ferreira da Silva Filho, Alberto Andrade Vergara, Antônio Fernando Ribeiro, Carlos Antônio Riedi, Elenara da Fonseca Andrade Procianoy, Fabíola Villac Adde, Francisco José Caldeira Reis, José Dirceu Ribeiro, Lídia Alice Torres, Marcelo Bicalho de Fuccio, Matias Epifanio, Mônica de Cássia Firmida, Neiva Damaceno, Norberto Ludwig-Neto, Paulo José Cauduro Maróstica, Samia Zahi Rached, Suzana Fonseca de Oliveira Melo, Leonardo Araújo Pinto, Luciana Freitas Velloso Monte, Laurinda Yoko Shinzato Higa, Tania Wrobel Folescu, Fernando Augusto de Lima Marson, Isabela Sad, Maria de Fátima Correa Pimenta Servidoni, Paulo Kussek, Salmo Raskin, Adriana Della Zuana, Albin Augustin, Anneliese Hoffmann, Beatriz Barbisan, Bruno Hochhegger, Carlos Emilio Levy, Claudine Sarmento da Veiga, Claudio Ricachinevsky, Concetta Esposito, Dante Escuissato, Diego Brandemburgo, Elisabeth Marques, Evanirso de Aquino, Gilberto Bueno Fischer, Joaquim Carlos Rodrigues, Leticia Machado, Lucia Muramato, Lusmaia Damasceno Camargo Costa, Marcio Donadio, Marcos César Santos de Castro, Maria Angela Ribeiro, Maria Angélica Santana, Mariane Canan, Marina Buarque de Almeida, Murilo Britto, Paulo Roth Tarso Dalcin, Regina Terse Trindade Ramos, Sonia Chiba, Valéria de Carvalho Martins, Claudine Lacerda, Eliana Barbosa, Elizabet Vilar Guimarães, Gabriel Hessel, Jocemara Gurmini, Lenycia Neri, Marcelo Coelho Nogueira, Mônica Chang Wayhs, Miriam Isabel Santos Simon, Arlene Gonçalves dos Santos Fernandes, Claudia de Castro de Silva, Cristiano Túlio Maciel Albuquerque, Edna Lúcia Souza, Fernando Antonio de Abreu e Silva, Paulo de Tarso Dalcin, Renata Maria de Noronha, Ricardo Teixeira, Sandra Helena Machado, Spencer Marcantonio Camargo, Tatiana Rozov, and Ticiana da Costa Rodrigues
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Male ,medicine.medical_specialty ,Practice guideline ,Cystic Fibrosis ,Nutritional Status ,Literature based ,Cystic fibrosis/therapy ,Cystic fibrosis ,Cftr gene ,Special Article ,03 medical and health sciences ,0302 clinical medicine ,Fibrose cística/diagnóstico ,medicine ,Humans ,030212 general & internal medicine ,Physical Therapy Modalities ,Gynecology ,Fibrose cística/terapia ,lcsh:RC705-779 ,Evidence-Based Medicine ,Guia de prática clínica ,business.industry ,Age Factors ,Cystic fibrosis/diagnosis ,Pediatric age ,lcsh:Diseases of the respiratory system ,medicine.disease ,Multisystem disease ,030228 respiratory system ,Practice Guidelines as Topic ,Quality of Life ,Referral center ,Fibrose cística/complicações ,Female ,business ,Cystic fibrosis/complications ,Brazil - Abstract
Cystic fibrosis (CF) is an autosomal recessive genetic disorder characterized by dysfunction of the CFTR gene. It is a multisystem disease that most often affects White individuals. In recent decades, various advances in the diagnosis and treatment of CF have drastically changed the scenario, resulting in a significant increase in survival and quality of life. In Brazil, the current neonatal screening program for CF has broad coverage, and most of the Brazilian states have referral centers for the follow-up of individuals with the disease. Previously, CF was limited to the pediatric age group. However, an increase in the number of adult CF patients has been observed, because of the greater number of individuals being diagnosed with atypical forms (with milder phenotypic expression) and because of the increase in life expectancy provided by the new treatments. However, there is still great heterogeneity among the different regions of Brazil in terms of the access of CF patients to diagnostic and therapeutic methods. The objective of these guidelines was to aggregate the main scientific evidence to guide the management of these patients. A group of 18 CF specialists devised 82 relevant clinical questions, divided into five categories: characteristics of a referral center; diagnosis; treatment of respiratory disease; gastrointestinal and nutritional treatment; and other aspects. Various professionals working in the area of CF in Brazil were invited to answer the questions devised by the coordinators. We used the PubMed database to search the available literature based on keywords, in order to find the best answers to these questions. RESUMO A fibrose cística (FC) é uma doença genética autossômica recessiva caracterizada pela disfunção do gene CFTR. Trata-se de uma doença multissistêmica que ocorre mais frequentemente em populações descendentes de caucasianos. Nas últimas décadas, diversos avanços no diagnóstico e tratamento da FC mudaram drasticamente o cenário dessa doença, com aumento expressivo da sobrevida e qualidade de vida. Atualmente, o Brasil dispõe de um programa de ampla cobertura para a triagem neonatal de FC e centros de referência distribuídos na maior parte desses estados para seguimento dos indivíduos. Antigamente confinada à faixa etária pediátrica, tem-se observado um aumento de pacientes adultos com FC tanto pelo maior número de diagnósticos de formas atípicas, de expressão fenotípica mais leve, assim como pelo aumento da expectativa de vida com os novos tratamentos. Entretanto, ainda se observa uma grande heterogeneidade no acesso aos métodos diagnósticos e terapêuticos para FC entre as diferentes regiões brasileiras. O objetivo dessas diretrizes foi reunir as principais evidências científicas que norteiam o manejo desses pacientes. Um grupo de 18 especialistas em FC elaborou 82 perguntas clínicas relevantes que foram divididas em cinco categorias: características de um centro de referência; diagnóstico; tratamento da doença respiratória; tratamento gastrointestinal e nutricional; e outros aspectos. Diversos profissionais brasileiros atuantes na área da FC foram convidados a responder as perguntas formuladas pelos coordenadores. A literatura disponível foi pesquisada na base de dados PubMed com palavras-chave, buscando-se as melhores respostas às perguntas dos autores.
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- 2017
23. Thoracolithiasis: A Rare Cause of Multiple Nodules
- Author
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Douglas Zaione Nascimento, Spencer Marcantonio Camargo, Bruno Hochhegger, Gláucia Zanetti, and Edson Marchiori
- Subjects
Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,business.industry ,Treatment outcome ,MEDLINE ,Middle Aged ,Critical Care and Intensive Care Medicine ,Dermatology ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Rare Diseases ,Treatment Outcome ,0302 clinical medicine ,Thoracic Diseases ,Humans ,Multiple Pulmonary Nodules ,Medicine ,business ,030217 neurology & neurosurgery - Published
- 2018
24. Non-anatomic lung resection by video-assisted thoracoscopic surgery
- Author
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Spencer Marcantonio Camargo, José Carlos Felicetti, Stephan Adamour Soder, and Renata Baú
- Subjects
medicine.medical_specialty ,Tuberculosis ,business.industry ,medicine.medical_treatment ,General surgery ,Incidence (epidemiology) ,Context (language use) ,Disease ,medicine.disease ,Video-assisted thoracoscopic surgery ,medicine ,Differential diagnosis ,Lung cancer ,business ,Lung cancer screening - Abstract
Most of the patients with pulmonary neoplasia are diagnosed at an advanced stage in Brazil. Consequently, the possibility of curative surgical treatment is restricted to less than 30% of patients with surgical indication. The difficulty of including a greater number of these individuals is in the difficulty of an early diagnosis of the disease, leading it to more advanced stages. Currently, despite the lack of statistical studies, a project is underway to recruit patients to set up a lung cancer screening program in Brazil. In other words, early stages amenable to surgical treatment. The prevalence of lung cancer has also been increasing in Brazil and tuberculosis has once again become a public health problem. The World Health Organization (WHO) estimates that 9.6 million cases of tuberculosis occurred in 2014. Out of this total, over 80% of the cases are concentrated in 22 countries, and Brazil ranks 19th in this classification. We also have to consider the possibility of the incidence of fungal diseases in a tropical country. With such disease profile, the presence of granulomas is high and differential diagnosis implies biopsies. In this context, small pulmonary nodules could be included in the surgical treatment for a differential diagnosis, or even for definitive treatment in certain patients with limitation for major surgeries, as in the case of lung cancer. For this group of patients, segmental, non-anatomic lung resection (wegde resection) could be performed with adequate results.
- Published
- 2018
25. Pulmonary calcified masses and gastric tumor: Incomplete Carney's triad
- Author
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Edson Marchiori, Spencer Marcantonio Camargo, and Bruno Hochhegger
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lcsh:RC705-779 ,Leiomyosarcoma ,Pathology ,medicine.medical_specialty ,business.industry ,Extra-Adrenal ,lcsh:Diseases of the respiratory system ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Paraganglioma ,Calcinosis ,030220 oncology & carcinogenesis ,Materials Chemistry ,Carney's triad ,medicine ,Gastric tumor ,030212 general & internal medicine ,business ,Chondroma - Abstract
Submitted by Biblioteca Suporte PUCRS (biblioteca.suporte@pucrs.br) on 2022-08-10T20:38:22Z No. of bitstreams: 2 Pulmonary_calcified_masses_and_gastric_tumor_Incomplete_Carneys_triad.pdf: 471057 bytes, checksum: 3c464ea1a6d32a26723b03b0d23a335d (MD5) Pulmonary_calcified_masses_and_gastric_tumor_Incomplete_Carneys_triad.pdf: 471057 bytes, checksum: 3c464ea1a6d32a26723b03b0d23a335d (MD5) Made available in DSpace on 2022-08-10T20:38:22Z (GMT). No. of bitstreams: 2 Pulmonary_calcified_masses_and_gastric_tumor_Incomplete_Carneys_triad.pdf: 471057 bytes, checksum: 3c464ea1a6d32a26723b03b0d23a335d (MD5) Pulmonary_calcified_masses_and_gastric_tumor_Incomplete_Carneys_triad.pdf: 471057 bytes, checksum: 3c464ea1a6d32a26723b03b0d23a335d (MD5) Previous issue date: 2017
- Published
- 2017
26. P1.16-028 Is Video-Assisted Thoracic Surgery a Safer Procedure for Lung Cancer Patients?
- Author
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Humberto Alves de Oliveira, Ricardo R. Terra, Álvaro Vigo, M.T. Ruiz Tsukazan, G. Fortunato, D. Pinto Filho, and Spencer Marcantonio Camargo
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,business.industry ,General surgery ,030204 cardiovascular system & hematology ,medicine.disease ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,Oncology ,Video assisted thoracic surgery ,SAFER ,medicine ,Lung cancer ,business - Published
- 2017
27. P1.08-058 VATS Lung Resection Analysis from Brazilian Society of Thoracic Surgery Database
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Leticia Leone Lauricella, Darcy Pinto, Humberto De Oliveira, Maria Teresa Ruiz Tsukazan, G. Fortunato, Spencer Marcantonio Camargo, and Ricardo R. Terra
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Oncology ,business.industry ,Cardiothoracic surgery ,medicine ,Lung resection ,business ,Surgery - Published
- 2017
28. Ground-glass nodules and CT-guided placement of platinum coils
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Klaus L. Irion, Marcos Duarte Guimarães, Fabiola Adelia Perin, Edson Marchiori, Spencer Marcantonio Camargo, Bruno Hochhegger, José de Jesus Peixoto Camargo, and José Carlos Felicetti
- Subjects
lcsh:RC705-779 ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Lung ,medicine.diagnostic_test ,Thoracoscope ,Cartas Ao Editor ,business.industry ,medicine.medical_treatment ,lcsh:Diseases of the respiratory system ,Palpation ,medicine.anatomical_structure ,medicine ,Radiology ,Thoracotomy ,business ,Lung tissue ,Letter to the Editor - Abstract
Various centers perform the excision of these small growing nodules using video-assisted thoracoscopic surgery (VATS) in order to minimize postoperative morbidity, as well as to remove as small a volume of lung tissue as possible. Small nodules are often visible with the thoracoscope if they lie within 5 mm of the visceral pleural surface; however, if they are located deeper in the lung, palpation is required in order to locate them for excision. A previous study found that, in a series of 92 consecutive patients undergoing VATS, 50 (54%) required conversion to thoracotomy.
- Published
- 2014
29. A right middle lobectomy and lingulectomy for treatment of bronchiectasis
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Spencer Marcantonio Camargo, Fabiola Adelia Perin, Stephan Adamour Soder, José de Jesus Peixoto Camargo, and José Carlos Felicetti
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Lingulectomy ,medicine.medical_specialty ,Bronchiectasis ,business.industry ,Materials Chemistry ,medicine ,business ,medicine.disease ,Surgery - Published
- 2018
30. Video-assisted thoracic surgery segmentectomies: Brazilian experience
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José de Jesus Peixoto Camargo, Fabiola Adelia Perin, Stephan Adamour Soder, Spencer Marcantonio Camargo, and José Carlos Felicetti
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education.field_of_study ,medicine.medical_specialty ,Lung resections ,business.industry ,General surgery ,Population ,Sublobar resection ,Cardiothoracic surgery ,Video assisted thoracic surgery ,medicine ,Lung cancer staging ,education ,business ,Lung cancer screening ,Minimally invasive procedures - Abstract
There is growing enthusiasm with lung resections by video-assisted thoracic surgery (VATS) technique in Brazil. The benefits of these minimally invasive procedures and their incorporation in the routine of many Brazilian centers produced a significant increase of sublobar and lobar resections in the country. The changes in our daily practice, including improvements in lung cancer staging, the rising of lung cancer screening programs and the analysis of several recent studies showing equivalent long-term outcomes with sublobar resections, while we treat often an elderly and poor performance population, have made the thoracic surgeon to look to a sublobar resection as a potentially curative procedure. We sought to analyze the Brazilian and institutional experience with VATS sublobar anatomical resections for treatment of benign and malignant diseases, and discuss technical aspects as well. Even though is much underreported, the outcomes of VATS segmentectomies resemble what is observed around the world and constitute in an effective surgery when well indicated. The Brazilian Society of Thoracic Surgery database is improving the notification by many centers and this better quality of data will provide us a deep knowledge about the results of our procedures national-wide.
- Published
- 2018
31. A basilar segmentectomy for lung cancer
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Fabiola Adelia Perin, José Carlos Felicetti, José de Jesus Peixoto Camargo, Spencer Marcantonio Camargo, and Stephan Adamour Soder
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Pathology ,medicine.medical_specialty ,business.industry ,Materials Chemistry ,medicine ,Lung cancer ,medicine.disease ,business - Published
- 2018
32. Posterior segmentectomy (S2) for lung cancer
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José de Jesus Peixoto Camargo, Fabiola Adelia Perin, Spencer Marcantonio Camargo, José Carlos Felicetti, and Stephan Adamour Soder
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medicine.medical_specialty ,business.industry ,Materials Chemistry ,Medicine ,Radiology ,business ,Lung cancer ,medicine.disease - Published
- 2018
33. Surgical treatment of bronchial carcinoid tumors: A single-center experience
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Spencer Marcantonio Camargo, Ana Luiza Schneider Moreira, Cristiano Feijó Andrade, Leonardo Signori, Tiago N. Machuca, José da Silva Moreira, Paulo Francisco Guerreiro Cardoso, José de Jesus Peixoto Camargo, and José Carlos Felicetti
- Subjects
Adult ,Male ,Pulmonary and Respiratory Medicine ,Cancer Research ,medicine.medical_specialty ,Adolescent ,Carcinoid tumors ,Pulmonary Surgical Procedures ,Carcinoid Tumor ,Chest pain ,Single Center ,Bronchoscopy ,Risk Factors ,Bronchial neoplasm ,Fiber Optic Technology ,Humans ,Medicine ,Aged ,Neoplasm Staging ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Pleural empyema ,Bronchial Neoplasms ,Respiratory disease ,Middle Aged ,Prognosis ,medicine.disease ,Survival Analysis ,Surgery ,Treatment Outcome ,Oncology ,Female ,medicine.symptom ,business ,Follow-Up Studies - Abstract
Background Bronchial carcinoid is an infrequent neoplasm with a neuroendocrine differentiation. Surgical treatment is the gold standard therapy, with procedures varying from sublobar resections to complex lung sparing broncoplastic procedures. This study evaluates the results of surgical treatment of bronchial carcinoids and its prognostic factors. Patients and methods Retrospective review of 126 consecutive patients who underwent surgical treatment for bronchial carcinoid tumors between December 1974 and July 2007. Results There were 70 females (55%) and the mean age was 46 years, ranging from 17 to 81 years. Upon clinical presentation, 38 patients (30%) have had recurrent respiratory tract infection, 31 (24%) cough, 16 (12%) chest pain and 25 (20%) were asymptomatic. Preoperative bronchoscopic diagnosis was obtained in 74 cases (58.7%). The procedures performed were: 19 sublobar resections (14,9%), 58 lobectomies (46%), 8 bilobectomies (6.3%), 6 pneumonectomies (4.7%), 2 sleeve segmentectomies (1.5%), 26 sleeve lobectomies (20.6%) and 9 bronchoplastic procedures without lung resection (7.1%). Operative mortality was 1.5% (n = 2) and morbidity was 25.8% (n = 32), including 12 respiratory tract infections and 4 reinterventions due to bleeding (3) and pleural empyema (1). Among the 112 patients available for follow-up, the overall survival at 3, 5 and 10 years was 89.2%, 85.5% and 79.8%, respectively. Five and 10-year survival for typical and atypical carcinoids were 91, 89% and 56, 47%, respectively. Overall disease-free survival at 5 years was 91.9% Statistical analysis showed that overall disease-free survival correlated with histology – typical vs. atypical – (p = 0.04) and stage (p = 0.02). Conclusion Surgery provides safe and adequate treatment to bronchial carcinoid tumors. Histology and stage were the main prognostic factors.
- Published
- 2010
34. Diagnosis of Invasive Aspergillosis in Lung Transplant Recipients by Detection of Galactomannan in the Bronchoalveolar Lavage Fluid
- Author
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Spencer Marcantonio Camargo, Luiz Carlos Severo, Melissa Orzechowski Xavier, Sadi Marcelo Schio, Alessandro C. Pasqualotto, Teresa C. T. Sukiennik, Leticia Sanchez, C. Costa, and José de Jesus Peixoto Camargo
- Subjects
Male ,Pathology ,Antifungal Agents ,Aspergillosis ,Gastroenterology ,Mannans ,chemistry.chemical_compound ,Medicine ,Cutoff ,Prospective Studies ,Child ,Invasive Pulmonary Aspergillosis ,medicine.diagnostic_test ,Incidence (epidemiology) ,Middle Aged ,respiratory system ,Prognosis ,Treatment Outcome ,medicine.anatomical_structure ,Female ,Bronchoalveolar Lavage Fluid ,Immunosuppressive Agents ,Lung Transplantation ,Adult ,medicine.medical_specialty ,Adolescent ,Sensitivity and Specificity ,Young Adult ,Galactomannan ,Predictive Value of Tests ,Internal medicine ,Bronchoscopy ,Humans ,False Positive Reactions ,Mycosis ,Aged ,Transplantation ,Chi-Square Distribution ,Lung ,business.industry ,Galactose ,medicine.disease ,respiratory tract diseases ,Bronchoalveolar lavage ,ROC Curve ,chemistry ,Reagent Kits, Diagnostic ,business ,Biomarkers - Abstract
Background. Galactomannan (GM) detection in serum samples has been used to diagnose invasive aspergillosis (IA). Limited sensitivity has been observed in lung transplant recipients, for whom bronchoalveolar lavage (BAL) testing has been advocated. Because airway colonization with Aspergillus species occurs frequently in these patients, false-positive GM results have been reported if the cutoff validated for sera is used (i.e., 0.5). Methods. Herein, we prospectively studied BAL fluid samples from 60 lung transplant patients to determine the optimal cutoff for BAL GM testing. Only one sample per patient was studied. BAL samples were vortexed and processed according to the manufacturer's instructions for serum samples. Sensitivity, specificity, and likelihood ratios were calculated in reference to proven or probable IA cases using receiver operating characteristic analysis. Results. Eight patients had IA during the study (incidence 13.3%), including four patients with proven IA. Aspergillosis increased 5-fold the risk of death in lung transplant recipients. The positive predictive value of a positive BAL GM test at the 0.5 cutoff was low (24.2%). Raising the cutoff improved test specificity without compromising sensitivity. The best cutoff was defined at 1.5 (sensitivity 100% and specificity 90.4%). Conclusions. This study reinforces the importance of BAL GM testing in lung transplant recipients, particularly to exclude the diagnosis of IA. To minimize the frequency of false-positive results, a higher test cutoff should be applied to BAL samples, in comparison with serum samples.
- Published
- 2010
35. Surgical treatment of benign tracheo-oesophageal fistulas with tracheal resection and oesophageal primary closure: is the muscle flap really necessary?☆
- Author
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José de Jesus Peixoto Camargo, Vivalde F. Lobato, Spencer Marcantonio Camargo, Carlos Remolina Medina, and Tiago N. Machuca
- Subjects
Adult ,Male ,Reoperation ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Adolescent ,Fistula ,Tracheoesophageal fistula ,Unnecessary Procedures ,Anastomosis ,Surgical Flaps ,Young Adult ,Esophagus ,Suture (anatomy) ,Intubation, Intratracheal ,medicine ,Paralysis ,Humans ,Muscle, Skeletal ,Aged ,business.industry ,Anastomosis, Surgical ,General Medicine ,Middle Aged ,medicine.disease ,Tracheal Stenosis ,Surgery ,Stenosis ,Treatment Outcome ,medicine.anatomical_structure ,Female ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Follow-Up Studies ,Tracheoesophageal Fistula - Abstract
Objectives: Nowadays, despite the advances of the low-pressure high-volume cuffs, post-intubation tracheo-oesophageal fistula (TEF) still poses a major challenge to thoracic surgeons. The original technique includes interposition of muscle flaps between suture lines to avoid recurrence. It is not clear if this manoeuvre is indispensable and, in fact, we and others have faced problems with it. Our aim is to present our experience with TEF management in a consecutive group with no muscle interposition. Methods: From June 1992 to November 2007, we evaluated 14 patients presenting with TEF, with a mean age of 44 years (from 18 to 79 years). Thirteen patients had a prolonged intubation history. The remaining case was a 40-year-old male with congenital TEF. Three patients had been previously submitted to failed repairs in other institutions. Ten patients had associated tracheal stenosis, which was subglottic in three of them. Regarding surgical technique, in all cases, we performed a single-staged procedure, which consisted of tracheal resection and anastomosis with double-layer oesophageal closure. In none of our cases was a muscle flap interposed between suture lines. Results: All operations were performed through a cervical incision; however, in one case, an extension with partial sternotomy was required. There was no operative mortality. Thirteen patients were extubated in the first 24 h after the procedure, while one patient required 48 h of mechanical ventilation. Four complications were recorded: one each of pneumonia and left vocal cord paralysis and two small tracheal dehiscences managed with a T-tube and a tracheostomy tube. After discharge, three patients returned to their native cities and were lost to follow-up. The remaining 11 patients have been followed up by a mean of 32 months (from three to 108 months), with 10 presenting excellent and one good anatomic and functional results. Conclusions: The single-staged repair with tracheal resection and anastomosis with oesophageal closure provides good short- and mid-term results for TEF management. The interposition of a muscle flap between suture lines may not be crucial to prevent recurrence.
- Published
- 2010
36. Surgical maneuvers for the management of bronchial complications in lung transplantation☆☆☆
- Author
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Tiago N. Machuca, José Carlos Felicetti, José de Jesus Peixoto Camargo, Sadi Marcelo Schio, Spencer Marcantonio Camargo, and Fabiola Adelia Perin
- Subjects
Adult ,Male ,Reoperation ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Pulmonary Fibrosis ,Fistula ,medicine.medical_treatment ,Bronchi ,Constriction, Pathologic ,Anastomosis ,Postoperative Complications ,Surgical Wound Dehiscence ,Humans ,Medicine ,Lung transplantation ,Lung ,business.industry ,Anastomosis, Surgical ,Sleeve Lobectomy ,General Medicine ,Bronchography ,Middle Aged ,respiratory system ,medicine.disease ,respiratory tract diseases ,Surgery ,Transplantation ,Stenosis ,Treatment Outcome ,medicine.anatomical_structure ,Female ,Bronchial Fistula ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business ,Complication ,Follow-Up Studies ,Lung Transplantation - Abstract
Background: Many advances have substantially improved the clinical results of lung transplantation. However, the incidence of bronchial complications is still high, with significant impact on survival and limited interventional strategies for complex cases. Our aim is to evaluate the surgical management of bronchial complications following lung transplantation. Methods: From May 1989 to June 2007, 251 patients were submittedtolungtransplantationatourinstitution.Infivecases, thebronchialcomplicationsobservedweredealtwithopensurgicalprocedures. Results: Complications surgically dealt were one broncho-arterial fistula and four stenosis. One left upper sleeve lobectomy, one right upper sleeve lobectomy and three segmental bronchial resections with anastomosis were performed. In all five cases the surgical procedure was successful and optimal bronchial healing was observed. Three patients died due to causes unrelated to the bronchial anastomosis 5, 21 and 32 months after the bronchoplastic procedure. Two patients are still alive and functionally well at 52 and 70 months post-bronchoplasty. Conclusions: Surgical management of bronchial complications after lung transplantation may be the last resort in complex, recalcitrant cases, nevertheless it is a feasible procedure and can provide good results not only on short- but also long-term follow-up. # 2008 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
- Published
- 2008
37. Superior Vena Cava Lipoma in an Asymptomatic Man
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Bruno Hochhegger, Edson Marchiori, Natália Henz Concatto, Klaus L. Irion, J.J. Camargo, and Spencer Marcantonio Camargo
- Subjects
Male ,Pulmonary and Respiratory Medicine ,Surgical resection ,medicine.medical_specialty ,Vena Cava, Superior ,Computed tomography ,Asymptomatic ,Lesion ,Superior vena cava ,medicine ,Humans ,Incidental Findings ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Middle Aged ,Lipoma ,medicine.disease ,Magnetic Resonance Imaging ,Vascular Neoplasms ,Asymptomatic Diseases ,Radiology ,medicine.symptom ,Tomography, X-Ray Computed ,business ,Lung cancer screening - Abstract
Submitted by Biblioteca Suporte PUCRS (biblioteca.suporte@pucrs.br) on 2022-08-16T19:20:44Z No. of bitstreams: 2 Superior_Vena_Cava_Lipoma_in_an_Asymptomatic_Man.pdf: 852005 bytes, checksum: adb95e8743175699017dce74ea0be38b (MD5) Superior_Vena_Cava_Lipoma_in_an_Asymptomatic_Man.pdf: 852005 bytes, checksum: adb95e8743175699017dce74ea0be38b (MD5) Made available in DSpace on 2022-08-16T19:20:44Z (GMT). No. of bitstreams: 2 Superior_Vena_Cava_Lipoma_in_an_Asymptomatic_Man.pdf: 852005 bytes, checksum: adb95e8743175699017dce74ea0be38b (MD5) Superior_Vena_Cava_Lipoma_in_an_Asymptomatic_Man.pdf: 852005 bytes, checksum: adb95e8743175699017dce74ea0be38b (MD5) Previous issue date: 2015
- Published
- 2015
38. P1.20: Lung Resection Analysis From Brazilian Society of Thoracic Surgery Database
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Leticia Leone Lauricella, Ricardo Mingarini Terra, Humberto Alves de Oliveira, Darcy Pinto, Maria Teresa Ruiz Tsukazan, G. Fortunato, and Spencer Marcantonio Camargo
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Oncology ,Cardiothoracic surgery ,business.industry ,medicine ,Anatomical resection ,Lung resection ,Stage (cooking) ,business ,Lung cancer ,medicine.disease ,Surgery - Published
- 2016
39. What is expected in lung function after lung transplantation due to end-stage pulmonary silicosis?
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Luzielio Alves Sidney-Filho, Bruno Hochhegger, Fabiola Adelia Perin, José da Silva Moreira, Pedro Reck dos Santos, Spencer Marcantonio Camargo, Sadi Marcelo Schio, José de Jesus Peixoto Camargo, Guilherme Watte, and José Carlos Felicetti
- Subjects
Male ,Spirometry ,medicine.medical_specialty ,Waiting Lists ,medicine.medical_treatment ,Silicosis ,Population ,Pulmonary function testing ,03 medical and health sciences ,FEV1/FVC ratio ,0302 clinical medicine ,DLCO ,Forced Expiratory Volume ,Internal medicine ,medicine ,Humans ,Lung transplantation ,education ,Retrospective Studies ,Transplantation ,education.field_of_study ,medicine.diagnostic_test ,business.industry ,Pneumoconiosis ,Middle Aged ,Prognosis ,medicine.disease ,030210 environmental & occupational health ,Respiratory Function Tests ,Surgery ,Survival Rate ,030228 respiratory system ,business ,Follow-Up Studies ,Lung Transplantation - Abstract
In the present study, we aimed to determine the impact of lung transplantation (LTx) on pulmonary function tests (PFTs) and survival among patients with end-stage silicosis. We included patients with end-stange silicosis on the wait list for LTx, between January 1989 and July 2015 (N=26). Sixteen of these patients received LTx; 10 were eligible, but did not undergo LTx (non-LTx) during the study period. Retrospective information on PFTs (spirometry [volumes and flows], 6-minute walking test [6MWT], and DLCO) was retrieved from patients’ medical charts, including baseline information for all patients, and follow-up information for the LTx. At baseline, most patients presented with spirometric and 6MWT values that were suggestive of severe disease (FEV1/FVC 76.5±29.7; 6MWT 267.4±104.5m). Significant increases in these values were observed at follow-up in the LTx (p=0.036 and 0.151, respectively). The overall median survival of patients in the LTx and non-LTx was 3.35 years (95% CI: 0.16–14.38) and 0.78 years (95% confidence interval [CI]: 0.12–3.65) (p=0.002), respectively. For patients with end-stage silicosis, LTx offers significant benefits regarding pulmonary function and survival when compared to non-LTx, and is a reliable tool to help this critical population of patients, whose only treatment option is LTx. This article is protected by copyright. All rights reserved.
- Published
- 2017
40. Lung Transplantation for Patients Older Than 65 Years: Is It a Feasible Option?
- Author
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Tiago N. Machuca, J.J. Camargo, Vivalde F. Lobato, Leticia Sanchez, José Carlos Felicetti, Spencer Marcantonio Camargo, Fabiola Adelia Perin, and Sadi Marcelo Schio
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Primary Graft Dysfunction ,law.invention ,Coronary artery disease ,law ,Humans ,Medicine ,Lung transplantation ,Contraindication ,Aged ,Retrospective Studies ,Mechanical ventilation ,Transplantation ,business.industry ,Extracorporeal circulation ,Atrial fibrillation ,medicine.disease ,Intensive care unit ,Surgery ,Feasibility Studies ,Female ,business ,Lung Transplantation - Abstract
Background Advanced age has been a relative contraindication to lung transplantation. However, the exact age limit for this procedure has not yet been established. The aim of this work is to present our experience with this particular group. Methods This retrospective review included medical charts of patients who underwent lung transplantation at our institution from January 2004 to February 2009: namely, 112 cadaveric lung transplants with 12 patients (10.7%) >65 years old. Results There were 9 male patients and the overall mean age was 68 years (range 66–72). The indications were pulmonary fibrosis in 8 and emphysema in 4 cases. Four patients had mild coronary artery disease and 4 systemic hypertension. All of the procedures were unilateral and only 2 required extracorporeal circulation. Only 5 patients received blood product transfusions intraoperatively; the mean ischemic time was 222 minutes. Four patients developed primary graft dysfunction, the mean requirement for mechanical ventilation was 30 hours, and the mean intensive care unit stay, 11 days. Postoperative complications were respiratory infections (n = 8), catheter-related infection (n = 1), atrial fibrillation (n = 2). The mean hospital stay was 28 days and the 1-year survival was 75%. Conclusion Lung transplantation is a feasible option for well-selected patients with end-stage pulmonary disease who are >65 years old. Our study reinforces the modern trend for unilateral procedures in this situation.
- Published
- 2011
41. Lung Transplantation for Lymphangioleiomyomatosis: Single-Center Brazilian Experience with No Chylothorax
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Iury Andrade Melo, J.J. Camargo, Sadi Marcelo Schio, Spencer Marcantonio Camargo, M.J. Losso, Tiago N. Machuca, Bruno Hochhegger, and José Carlos Felicetti
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,medicine ,Humans ,Lung transplantation ,Lymphangioleiomyomatosis ,Retrospective Studies ,Transplantation ,Lung ,business.industry ,Respiratory disease ,Chylothorax ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Pneumothorax ,Female ,business ,Pleurodesis ,Brazil ,Lung Transplantation - Abstract
Background Lymphangioleiomyomatosis (LAM), a rare cystic disease characterized by proliferation of smooth muscle cells in the lung interstitium, almost exclusively affects females in their reproductive years. Lung transplantation has been extablished as effective therapy for end-stage pulmonary LAM. Methods This retrospective study includes lung transplantation patients with LAM at a single institution between 1989 and 2009. Results During the study period we performed 300 lung transplantations, and in 10 cases the recipients had LAM. All patients were females with a mean age of 43.8 years. The mean time from the diagnosis to lung transplantation was 5 years. Seven patients had experienced previous pneumothoraces, five of whom were treated with pleurodesis. In all patients we performed a single-lung transplantation (left-sided = 9 and right-sided = 1). In three cases, the pleurodesis was on the same side as the transplantation, with great intraoperative bleeding in one subject (left pleurectomy). There was one early death due to infective endocarditis at posttransplant day 19. The median length of mechanical ventilation was 13 hours, while the mean hospital stay was 16.75 days. There was no case of chylothorax. Late complications included one case of native lung pneumothorax, one diaphragmatic hernia, one posttransplant lymphoproliferative disease, one respiratory sepsis, and one mycobacterial infection. The 1- and 3-year survival rates were 90% and 80%, respectively. Conclusion Lung transplantation is a feasible therapeutic option for patients with LAM, despite previous ipsilateral pleurodesis. The left-sided predilection for our procedures may have been responsible for the absence of chylothorax in this series.
- Published
- 2011
42. Multiple Synchronous Bronchial Carcinoid Tumors: Report of a Case
- Author
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Ana Luiza Schneider Moreira, Spencer Marcantonio Camargo, J.J. Camargo, José da Silva Moreira, Sadi Marcelo Schio, and Tiago N. Machuca
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Carcinoid tumors ,medicine.medical_treatment ,Treatment outcome ,Carcinoid Tumor ,Bronchial carcinoid ,Neoplasms, Multiple Primary ,X ray computed ,Humans ,Medicine ,Thoracotomy ,Pathological ,Lung ,business.industry ,Bronchial Neoplasms ,Middle Aged ,medicine.disease ,Treatment Outcome ,medicine.anatomical_structure ,Nodular lesions ,Lymph Node Excision ,Female ,Surgery ,Radiology ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business - Abstract
Peripheral bronchial carcinoids are uncommon. Their presentation as synchronous tumors is rare and limited to anecdotal cases.We report the case of a 62-year-old female with the radiological finding of multiple bilateral nodular lesions. Bilateral sequential thoracotomies were performed and all three nodules were treated by sublobar resections. Pathological examination revealed all specimens to be carcinoid tumors and subsequent investigation confirmed the lung as the primary site. A review of previous cases of multiple carcinoids is presented and the particularities of their management are discussed.
- Published
- 2009
43. Lung transplantation without the use of cardiopulmonary bypass in a patient with Kartagener syndrome
- Author
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Spencer Marcantonio Camargo, José de Jesus Peixoto Camargo, Tiago N. Machuca, Luzielio Alves Sidney Filho, Sadi Marcelo Schio, José Carlos Felicetti, Fabiola Adelia Perin, and Leticia Sanchez
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Pulmonary and Respiratory Medicine ,Gynecology ,medicine.medical_specialty ,law ,business.industry ,medicine.medical_treatment ,medicine ,Cardiopulmonary bypass ,Lung transplantation ,Kartagener Syndrome ,business ,law.invention - Abstract
A discinesia ciliar primaria e uma condicao rara que evolui com a formacao de bronquiectasias, e invariavelmente o tratamento cirurgico esta indicado; alguns desses pacientes evoluem para doenca pulmonar avancada, refrataria ao tratamento clinico e as resseccoes cirurgicas, tornando-se, portanto, candidatos ao transplante pulmonar. Quando associada a dextrocardia, bronquiectasias e sinusopatia cronica, a discinesia ciliar primaria e chamada de sindrome de Kartagener e e considerada como uma contraindicacao de transplante pulmonar por muitos centros.
- Published
- 2012
44. F-056OUTCOMES OF ANATOMIC LUNG RESECTIONS IN BRAZIL: RESULTS OF A NATIONAL DATABASE FROM THE BRAZILIAN SOCIETY OF THORACIC SURGERY
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Humberto Alves de Oliveira, Leticia Leone Lauricella, D. Pinto Filho, Ricardo R. Terra, Maria Teresa Ruiz Tsukazan, Spencer Marcantonio Camargo, and G. Fortunato
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Lung resections ,business.industry ,Cardiothoracic surgery ,Medicine ,Surgery ,National database ,Cardiology and Cardiovascular Medicine ,business - Published
- 2016
45. Pulmonary Infection by a Negative Acid-Fast Bacilli Nocardia cyriacigeorgica in a Patient With Bronchiectasis and Past History of Tuberculosis (TB)
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Eduardo Garcia, Eduardo Morais Everling, Mara Rubia Lima, Aline Siebeneichler, Everton Inamine, Bruno Hochhegger, Rafael Kiss, Spencer Marcantonio Camargo, Patrícia Yuri Noguchi, and Bianca Schwengber
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Pulmonary and Respiratory Medicine ,Tuberculosis ,Bronchiectasis ,biology ,business.industry ,Lung infection ,Nocardia ,Pulmonary infection ,Critical Care and Intensive Care Medicine ,biology.organism_classification ,medicine.disease ,Past history ,Microbiology ,Acid-fast ,medicine ,NOCARDIA CYRIACIGEORGICA ,Cardiology and Cardiovascular Medicine ,business - Published
- 2016
46. Three Years History of Repeated Pneumonias on the Same Location Associated to Bronchial Typcal Carcinoid Tumor
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M. A. Klein, Ana Moreira, Gabriela Buffon, José Cláudio Fonseca Moreira, Mara Rubia Lima, Jackeline Souza, Felipe Sanches, Camila Zuconi, Bruno Hochhegger, and Spencer Marcantonio Camargo
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Pulmonary and Respiratory Medicine ,Pneumonia ,medicine.medical_specialty ,business.industry ,General surgery ,Internal medicine ,Medicine ,Cardiology and Cardiovascular Medicine ,Critical Care and Intensive Care Medicine ,business ,medicine.disease - Published
- 2016
47. Twelve-year survival of the first living-donor pediatric lung transplantation in Brazil
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Spencer Marcantonio Camargo, Tiago N. Machuca, Luzielio Alves Sidney Filho, José de Jesus Peixoto Camargo, José Carlos Felicetti, and Sadi Marcelo Schio
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Male ,business.industry ,Treatment Outcome ,Pediatrics, Perinatology and Child Health ,Living Donors ,Humans ,Medicine ,Survivors ,Child ,business ,Bronchiolitis Obliterans ,Humanities ,Brazil ,Lung Transplantation - Abstract
OBJETIVO: Apresentar o acompanhamento a longo prazo do primeiro caso de transplante pulmonar intervivos realizado na America Latina. DESCRICAO: Paciente do sexo masculino, com 12 anos de idade, portador de bronquiolite obliterante com doenca pulmonar avancada. Fazia uso de oxigenio domiciliar continuo, com dispneia aos minimos esforcos. Foi submetido a transplante pulmonar bilateral com doadores vivos. A cirurgia foi realizada utilizando os lobos inferiores esquerdo e direito de dois doadores diferentes e com grau de parentesco com o receptor. No segundo lado (direito), foi necessario emprego de circulacao extracorporea. O transplante nao teve intercorrencias, e o paciente foi extubado com 14 horas de pos-operatorio; com 44 dias, recebeu alta hospitalar, apos a resolucao de complicacoes infecciosas, imunologicas e medicamentosas. Apos 12 anos de seguimento, encontra-se com funcao pulmonar preservada e desempenha normalmente suas atividades. COMENTARIOS: O transplante pulmonar intervivos e um procedimento de alta complexidade que pode contribuir para o tratamento de algumas pneumopatias na infância. Essa populacao se beneficia dessa abordagem, uma vez que a disponibilidade de doadores pediatricos e muito rara, e as pneumopatias pediatricas tendem a seguir um curso imprevisivel.
- Published
- 2012
48. Guidelines for potential multiple organ donors (adult). Part III: organ-specific recommendations
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Álvaro Réa-Neto, Raquel Wanzuita, Valter Duro Garcia, Spencer Marcantonio Camargo, Rafael Lisboa de Souza, Gerson Costa, Nazah Cherif Mohamad Youssef, Glauco Adrieno Westphal, Fernando Suparregui Dias, M. Bartz, Frederico Bruzzi de Carvalho, José Mario Meira Teles, Fernando Osni Machado, Jorge Dias de Matos, Cassiano Teixeira, José de Jesus Peixoto Camargo, Alfredo Inácio Fiorelli, Marilda Mazzali, Ben-Hur Ferraz Neto, Anderson R.R. Gonçalves, Joel de Andrade, Viviane Renata Zaclikevis, Marcelo Nogara, Rogério Fernandes, Marcelo de Oliveira Maia, Cristiano Augusto Franke, Kalinca Daberkow Vieira, Maria Emília Coelho, Milton Caldeira Filho, Péricles Almeida Delfino Duarte, and Karine Gerent
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Cardiac function curve ,medicine.medical_specialty ,business.industry ,Transplant recipient ,lcsh:Medical emergencies. Critical care. Intensive care. First aid ,Hemodynamics ,General Medicine ,lcsh:RC86-88.9 ,Critical Care and Intensive Care Medicine ,Internal medicine ,Intensive care ,medicine ,Cardiology ,Liver function ,business - Abstract
A morte encefálica induz várias alterações fisiopatológicas que podem causar lesões em rins, pulmões, coração e fígado. Portanto, a atuação do intensivista durante a manutenção do potencial doador falecido exige cuidados específicos com estes órgãos visando sua maior viabilidade para transplantes. O manejo hemodinâmico cuidadoso, os cuidados ventilatórios e de higiene brônquica minimizam a perda de rins e pulmões para o transplante. A avaliação da condição morfológica e funcional do coração auxilia na avaliação do potencial transplantável deste órgão. Por fim, a avaliação da função hepática, assim como o controle metabólico e a realização de sorologias virais são fundamentais para a orientação das equipes transplantadoras na seleção do órgão a ser doado e no cuidado com o receptor. Brain death (BD) alters the pathophysiology of patients and may damage the kidneys, the lungs, the heart and the liver. To obtain better quality transplant organs, intensive care physicians in charge of the maintenance of deceased donors should attentively monitor these organs. Careful hemodynamic, ventilatory and bronchial clearance management minimizes the loss of kidneys and lungs. The evaluation of cardiac function and morphology supports the transplant viability assessment of the heart. The monitoring of liver function, the management of the patient's metabolic status and the evaluation of viral serology are fundamental for organ selection by the transplant teams and for the care of the transplant recipient
- Published
- 2011
49. Prognostic factors in lung transplantation: the Santa Casa de Porto Alegre experience
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José da Silva Moreira, Tiago N. Machuca, José Carlos Felicetti, Spencer Marcantonio Camargo, Vivalde F. Lobato, José de Jesus Peixoto Camargo, C. Costa, and Sadi Marcelo Schio
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Adult ,Male ,medicine.medical_specialty ,Central Venous Pressure ,medicine.medical_treatment ,law.invention ,Pulmonary Disease, Chronic Obstructive ,Postoperative Complications ,law ,medicine ,Lung transplantation ,Humans ,Pulmonary wedge pressure ,Dialysis ,Aged ,Mechanical ventilation ,Transplantation ,Cardiopulmonary Bypass ,business.industry ,Respiratory disease ,Hazard ratio ,Middle Aged ,medicine.disease ,Prognosis ,Intensive care unit ,Tissue Donors ,Surgery ,Anesthesia ,Multivariate Analysis ,Female ,business ,Brazil ,Lung Transplantation - Abstract
Background. Lung transplantation (LT) has been established as a current therapy for selected patients with end-stage lung disease. Different prognostic factors have been reported by transplant centers. The objective of this study is to report our recent results with LT and to search for prognostic factors. Methods. We performed a retrospective analysis of 130 patients who underwent LT at our institution from January 2004 to July 2009. Donor, recipient, intraoperative, and postoperative variables were collected. Results. The mean age was 53.14 years (ranging from 8 to 72 years) and 80 (61.5%) were male. The main causes of end-stage respiratory disease were pulmonary fibrosis 53 (40.7%) and chronic obstructive pulmonary disease 52 (40%). The actuarial 1-year survival was 67.7%. Variables correlated with survival were age (P=0.004), distance in the 6-min walk test (P=0.007), coronary heart disease (P=0.001),cardiopulmonary bypass (P=0.02), intraoperative transfusion of red blood cells (P=0.016), increasing central venous pressure at 24th postoperative hour (P=0.001), increasing pulmonary capillary wedge pressure at 24th postoperative hour (P=0.01); length of intubation (P
- Published
- 2011
50. Synchronous pulmonary and hepatic nodules in a patient with previous bronchogenic carcinoma: the relevance of histopathological confirmation
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José de Jesus Peixoto, Camargo, Tiago Noguchi, Machuca, Spencer Marcantonio, Camargo, Sadi Marcelo, Schio, and Rodrigo Moreira, Bello
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Lung Diseases ,Male ,Carcinoma, Bronchogenic ,Carcinoma, Hepatocellular ,Lung Neoplasms ,Biopsy ,Liver Neoplasms ,Calcinosis ,Humans ,Tomography, X-Ray Computed ,Aged ,Neoplasm Staging - Abstract
The synchronous presentation of pulmonary and hepatic nodules in a patient with previously resected bronchogenic carcinoma raises suspicion of recurrence and mandates restaging. We present the case of a 71-year-old male with a history of lobectomy with pericardial resection and mediastinal lymphadenectomy (T3N0M0). At five years after the operation, he presented with a new pulmonary lesion. Restaging detected a synchronous nodule in the liver. Despite the strong suspicion of tumor recurrence, further investigation with a percutaneous liver biopsy revealed hepatocellular carcinoma. In order to investigate the etiology of the pulmonary lesion (hypotheses of recurrent bronchial cancer and of metastatic hepatocellular carcinoma), an open lung biopsy was performed, which revealed chronic inflammatory tissue with foci of anthracosis and dystrophic calcification. The patient was submitted to a non-anatomic resection of the liver lesion. The postoperative course was uneventful, and the patient was discharged on postoperative day 10. This report highlights the relevance of the histopathological diagnosis in patients with a history of bronchogenic carcinoma and suspicion of tumor recurrence. Differential diagnoses and the treatment administered are discussed.
- Published
- 2008
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