166 results on '"Spencer, Robert H"'
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2. Pharmacokinetics, Metabolism, and Excretion of Intravenous [14C]Difelikefalin in Healthy Subjects and Subjects on Hemodialysis
3. The Burden of Pruritus Associated With CKD: A Mixed Methods Analysis Among Patients Undergoing Dialysis
4. A phase 2 study of oral difelikefalin in subjects with chronic kidney disease and moderate-to-severe pruritus
5. Psychometric validation and meaningful change thresholds of the Worst Itching Intensity Numerical Rating Scale for assessing itch in patients with chronic kidney disease-associated pruritus
6. Structure of the MscL Homolog from Mycobacterium tuberculosis: A Gated Mechanosensitive Ion Channel
7. Assessment of the physical dependence potential of difelikefalin: Randomized placebo‐controlled study in patients receiving hemodialysis
8. Crystal Structure of Inhibitor-Bound Human 5-Lipoxygenase: Activating Protein
9. Evaluation of the abuse potential of difelikefalin, a selective kappa‐opioid receptor agonist, in recreational polydrug users
10. Clinically meaningful change in itch intensity scores: An evaluation in patients with chronic kidney disease–associated pruritus
11. Additional file 1 of Psychometric validation and meaningful change thresholds of the Worst Itching Intensity Numerical Rating Scale for assessing itch in patients with chronic kidney disease-associated pruritus
12. Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients
13. The right internal controls prevent fraud and loss: the larger the organization, the more formal the requirement for internal controls; the smaller the organization, the more resources-constrained it is. Yet, some simple procedures can be applied for writing internal controls that can be utilized for all levels of business
14. Analogs of MK-499 are differentially affected by a mutation in the S6 domain of the hERG K+ channel
15. High-throughput analysis of drug binding interactions for the human cardiac channel, Kv1.5
16. Evaluation of the abuse potential of difelikefalin, a selective kappa‐opioid receptor agonist, in recreational polydrug users.
17. A Family of Three Mouse Potassium Channel Genes with Intronless Coding Regions
18. Time to go paperless: just preparing for the switchover will save you money.
19. Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics
20. Influence of Gear Design Parameters on Gearbox Radiated Noise
21. The relative noise levels of parallel axis gear sets with various contact ratios and gear tooth forms
22. Gear sound levels with various tooth contact ratios and forms
23. Investigation of the κ-opioid receptor agonist cr845 and reference comparator, butorphanol, in rats trained to discriminate (−)pentazocine from saline
24. Structural Studies of MscL, a Gated Mechanosensitive Ion Channel
25. Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
26. Subjective and objective evidence of low abuse potential of the peripherally-acting kappa opioid, CR845, compared with pentazocine
27. Poster 147 CR845, a Peripheral Kappa Opioid Receptor Agonist, Provides Better Pain Relief With Less Nausea and Vomiting Than Placebo in Patients After Bunionectomy
28. Poster 146 CR845, a Novel Peripherally-Acting Kappa Opioid Receptor Agonist, Has Low Abuse Potential Compared With Pentazocine
29. Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3)
30. Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channel
31. Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3)
32. Technology best practices
33. Reversal of acid-induced and inflammatory pain by the selective ASIC3 inhibitor, APETx2
34. The alpha-helix and the organization and gating of channels
35. Synthesis, Structure−Activity Relationship, and Pharmacological Profile of Analogs of The ASIC-3 Inhibitor A-317567
36. Peripheral mechanisms of pain and analgesia
37. Ion Channel Structural Studies
38. Integration of Postclosure Safety Analysis with Repository Design for the Yucca Mountain Repository through the Selection of Design Control Parameters
39. Crystallographic Analyses of Ion Channels: Lessons and Challenges
40. Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors
41. Potent antagonists of the Kv1.5 potassium channel: Synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides
42. Design and Synthesis of Novel Isoquinoline-3-nitriles as Orally Bioavailable Kv1.5 Antagonists for the Treatment of Atrial Fibrillation
43. Approaches for Ion Channel Structural Studies
44. TBX5 Genetic Testing Validates Strict Clinical Criteria for Holt-Oram Syndrome
45. High Throughput Assay Technologies for Ion Channel Drug Discovery
46. Potent antagonists of the Kv1.5 potassium channel: Synthesis and evaluation of analogous N, N-diisopropyl-2-(pyridine-3-yl)acetamides
47. Integration of Postclosure Safety Analysis with Repository Design for the Yucca Mountain Repository through the Selection of Design Control Parameters.
48. The α-Helix and the Organization and Gating of Channels
49. Monte Carlo modeling of radiation dose distributions in intravascular radiation therapy
50. Crystallographic Analyses of Ion Channels: Lessons and Challenges
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