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Your search keyword '"Spencer, Julianne"' showing total 23 results
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23 results on '"Spencer, Julianne"'

2. Feasibility of Coronary Access Following Redo-TAVR for Evolut Failure: A Computed Tomography Simulation Study

Author

Tang, Gilbert H.L., Spencer, Julianne, Rogers, Toby, Grubb, Kendra J., Gleason, Patrick, Gada, Hemal, Mahoney, Paul, Dauerman, Harold L., Forrest, John K., Reardon, Michael J., Blanke, Philipp, Leipsic, Jonathon A., Abdel-Wahab, Mohamed, Attizzani, Guilherme F., Puri, Rishi, Caskey, Michael, Chung, Christine J., Chen, Ying-Hwa, Dudek, Dariusz, Allen, Keith B., Chhatriwalla, Adnan K., Htun, Wah Wah, Blackman, Daniel J., Tarantini, Giuseppe, Zhingre Sanchez, Jorge, Schwartz, Greta, Popma, Jeffrey J., and Sathananthan, Janarthanan

Published
2023
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3. Hydrodynamic Assessment of Explanted Degenerated Transcatheter Aortic Valves

Author

Sathananthan, Janarthanan, primary, Nigade, Anish, additional, Meier, David, additional, Navarro, Dante, additional, Spencer, Julianne, additional, Lai, Althea, additional, Gill, Hacina, additional, Pirelli, Luigi, additional, Webb, John G., additional, Wood, David A., additional, Lutter, Georg, additional, Puehler, Thomas, additional, Tang, Gilbert H.L., additional, Fukuhara, Shinichi, additional, and Sellers, Stephanie L., additional

Published
2024
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6. COMPUTED TOMOGRAPHY TO ASSESS FEASIBILITY OF CORONARY ACCESS FOLLOWING BALLOON-EXPANDABLE VALVE IMPLANTATION WITHIN A SUPRA-ANNULAR TRANSCATHETER VALVE

Author

Rogers, Toby, primary, Spencer, Julianne, additional, Tang, Gilbert Hin-Lung, additional, Grubb, Kendra Janel, additional, Gleason, Patrick, additional, Gada, Hemal, additional, Mahoney, Paul D., additional, Dauerman, Harold L., additional, Forrest, John K., additional, Reardon, Michael J., additional, Abdel-Wahab, Mohamed, additional, Puri, Rishi, additional, Attizzani, Guilherme, additional, Caskey, Michael, additional, Chung, Christine, additional, Chen, Ying-Hwa, additional, Htun, Wah Wah, additional, Sanchez, Jorge Zhingre, additional, Schwartz, Greta, additional, Popma, Jeffrey J., additional, and Sathananthan, Janarthanan, additional

Published
2023
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21. The implications and effects of coronary venous anatomy on clinical interventions

Author

Spencer, Julianne

Subjects
Anatomy, Cardiac veins, Coronary veins, Pacing
Abstract

Background: The anatomy of the coronary venous system has important implications for clinical interventions including cardiac resynchronization therapy, ablation therapy, defibrillation, perfusion therapy, and mitral valve annuloplasty. Method: The effect of coronary venous anatomy on cardiac therapies was assessed by characterizing the venous anatomy, the clinically relevant adjacent anatomy, and the anatomical effect on pacing thresholds. Coronary venous anatomy was evaluated using perfusion-fixed human cardiac specimens with direct measurements using a microscribe digitizer and with contrast-computed tomography. Contrast-computed tomography and magnetic resonance imaging were used to investigate the coronary venous anatomical relationship with the phrenic nerve, coronary arteries, and mitral isthmus. Finally, electrostatic field simulations were performed to evaluate how cardiac anatomy and pacing electrode location affect clinical pacing thresholds and phrenic nerve stimulation. Results/Discussion: In short, the human coronary venous system is a highly variable physiological system that is essential for several current cardiac therapies. The consistent observation of high anatomical variation throughout all of the performed studies stress the clinical importance of understanding a given patient's individual anatomy when performing a planned intervention within the coronary veins. Importantly, the database of coronary venous anatomical parameters and pacing thresholds presented here can be incorporated into the development and implementation of therapies that utilize these vessels.

Published
2013

23. Feasibility of redo-TAVI in self-expanding Evolut valves: a CT analysis from the Evolut Low Risk Trial substudy.

Author

Grubb KJ, Shekiladze N, Spencer J, Perdoncin E, Tang GHL, Xie J, Lisko J, Sanchez JZ, Lucas LM, Sathananthan J, Rogers T, Deeb GM, Fukuhara S, Blanke P, Leipsic JA, Forrest JK, Reardon MJ, and Gleason P

Subjects
Female, Humans, Aortic Valve diagnostic imaging, Aortic Valve surgery, Feasibility Studies, Prosthesis Design, Tomography, X-Ray Computed, Treatment Outcome, Aortic Valve Stenosis diagnostic imaging, Aortic Valve Stenosis surgery, Heart Valve Prosthesis, Transcatheter Aortic Valve Replacement methods
Abstract

Background: Transcatheter aortic valve implantation in an existing transcatheter valve (redo-TAVI) pins the index valve leaflets in the open position (neoskirt), which can cause coronary flow compromise and limit access. Whether anatomy may preclude redo-TAVI in self-expanding Evolut valves is unknown., Aims: We aimed to evaluate the anatomical feasibility of redo-TAVI by simulating implantation of a balloon-expandable SAPIEN 3 (S3) within an Evolut or an Evolut within an Evolut., Methods: A total of 204 post-TAVI computed tomography (CT) scans from the Evolut Low Risk CT substudy were analysed. Five redo-TAVI positions were evaluated: S3-in-Evolut inflow-to-inflow, S3 outflow at Evolut nodes 4, 5, and 6, and Evolut-in-Evolut inflow-to-inflow. Univariable modelling identified pre-TAVI clinical characteristics, CT anatomical parameters, and procedural variables associated with coronary flow compromise using the neoskirt height and post-TAVI aortic root dimensions., Results: The risk of coronary flow compromise was lowest when the S3 outflow was at Evolut node 4 (20%) and highest when at Evolut node 6 (75%). The highest likelihood of preserving coronary accessibility occurred with the S3 outflow at Evolut node 4. Female sex and higher body mass index were associated with a higher risk of coronary flow compromise, as were a smaller annulus diameter, lower sinus of Valsalva height and width, shorter coronary height, smaller sinotubular junction diameter, and shallower Evolut implant depth., Conclusions: The feasibility of redo-TAVI after Evolut failure is multifactorial and relates to the native annular anatomy, as well as the implantation depth of the index and second bioprostheses. Placement of an S3 at a lower Evolut position may reduce the risk of coronary flow compromise while preserving coronary access., Clinicaltrials: gov: NCT02701283.

Published
2023
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