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1. The Solar Orbiter SPICE instrument -- An extreme UV imaging spectrometer

Author

Consortium, The SPICE, Anderson, M., Appourchaux, T., Auchère, F., Cuadrado, R. Aznar, Barbay, J., Baudin, F., Beardsley, S., Bocchialini, K., Borgo, B., Bruzzi, D., Buchlin, E., Burton, G., Blüchel, V., Caldwell, M., Caminade, S., Carlsson, M., Curdt, W., Davenne, J., Davila, J., DeForest, C. E., Del Zanna, G., Drummond, D., Dubau, J., Dumesnil, C., Dunn, G., Eccleston, P., Fludra, A., Fredvik, T., Gabriel, A., Giunta, A., Gottwald, A., Griffin, D., Grundy, T., Guest, S., Gyo, M., Haberreiter, M., Hansteen, V., Harrison, R., Hassler, D. M., Haugan, S. V. H., Howe, C., Janvier, M., Klein, R., Koller, S., Kucera, T. A., Kouliche, D., Marsch, E., Marshall, A., Marshall, G., Matthews, S. A., McQuirk, C., Meining, S., Mercier, C., Morris, N., Morse, T., Munro, G., Parenti, S., Pastor-Santos, C., Peter, H., Pfiffner, D., Phelan, P., Philippon, A., Richards, A., Rogers, K., Sawyer, C., Schlatter, P., Schmutz, W., Schühle, U., Shaughnessy, B., Sidher, S., Solanki, S. K., Speight, R., Spescha, M., Szwec, N., Tamiatto, C., Teriaca, L., Thompson, W., Tosh, I., Tustain, S., Vial, J. -C., Walls, B., Waltham, N., Wimmer-Schweingruber, R., Woodward, S., Young, P., De Groof, A., Pacros, A., Williams, D., and Müller, D.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract

The Spectral Imaging of the Coronal Environment (SPICE) instrument is a high-resolution imaging spectrometer operating at extreme ultraviolet (EUV) wavelengths. In this paper, we present the concept, design, and pre-launch performance of this facility instrument on the ESA/NASA Solar Orbiter mission. The goal of this paper is to give prospective users a better understanding of the possible types of observations, the data acquisition, and the sources that contribute to the instrument's signal. The paper discusses the science objectives, with a focus on the SPICE-specific aspects, before presenting the instrument's design, including optical, mechanical, thermal, and electronics aspects. This is followed by a characterisation and calibration of the instrument's performance. The paper concludes with descriptions of the operations concept and data processing. The performance measurements of the various instrument parameters meet the requirements derived from the mission's science objectives. The SPICE instrument is ready to perform measurements that will provide vital contributions to the scientific success of the Solar Orbiter mission., Comment: A&A, accepted 19 August 2019; 26 pages, 25 figures

Published
2019
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2. Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition

Author

Kammermeier, Jochen, Lamb, Christopher A, Jones, Kelsey D J, Anderson, Carl A, Baple, Emma L, Bolton, Chrissy, Braggins, Helen, Coulter, Tanya I, Gilmour, Kimberly C, Gregory, Vicki, Hambleton, Sophie, Hartley, David, Hawthorne, A Barney, Hearn, Sarah, Laurence, Arian, Parkes, Miles, Russell, Richard K, Speight, R Alexander, Travis, Simon, Wilson, David C, and Uhlig, Holm H

Published
2023
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3. Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

Author

Islam, Madiha, Croft, Nick, Cipriano, Bessie, Francia, Caroline, Khalid, Nosheen, Kingston, Ashley, Lee, Irish, Lehmann, Anouk, Naik, Kinnari, Samuels, Kevin, Plaatjies, Nicolene, Khatun, Hafiza, Bokth, Farjana, Pabriaga, Elise, Saich, Rebecca, Cousins, Hayley, Fraser, Wendy, Thomas, Rachel, Brown, Matthew, White, Benjamin, Kirkineziadis, Nikolaos, Tilley, Bernadette, Porter, Pennie, Bryant, Rachel, Robaczewska, Natalia, Muhammed, Rafeeq, Bi, Rehana, Cotter, Catherine, Grove, Jayne, Hong, Kate, Howman, Ruth, Mitchell, Monica, Clayton, Sophie, Rogers, Louise, Sultan, Sugrah, Rooney, Melanie, Cottrill, Charlotte, Singh, Salil, Dawe, Chris, Hull, Robert, Silva, Natalie, Chadwick, Julie, Robertson, Laura, Manning, Jonathan, Finlayson, Lauren, Roebuck, Allison, Dawson, Joy, Sonwalkar, Sunil, Chambers, Naomi, Robinson, Matthew, Haigh, Andrew, Matapure, Lear, Raine, Tim, George, Varun, Kapizioni, Christina, Strongili, Konstantina, Thompson, Tina, Ahmed, Mohamed, Kontos, Christos, Dawson, Claire, Bourges, Christophe, Barbutti, Isabella, Gozzard, Megan E, Hendy, Philip, Bull, Rhian, Costa, Patricia, Davey, Lisa, Hannington, Hayley, Nundlall, Kribashnie, Martins, Catarina, Avanzi, Laura, Carungcong, Jaime, Barr, Sabrina, Appleby, Richard, Johnson, Emma, Shakweh, Eathar, Phillis, Kath, Gascoyne, Rachel, Crowder, Amanda, Whileman, Amanda, London, Ian, Grounds, Jenny, Martin, Emmeline, Pajak, Susie, Price, Jude, Cawley, Kathryn, Powell, Sandra, Kearsley, Nichola, Dhar, Anjan, Brown, Ellen, Cowton, Amanda, Stamp, Kimberley, Warner, Ben, Stuart, Carmel, Lacey, Louise, de Silva, Shanika, Allcock, Clare, Harvey, Philip, Jones, Lesley, Cooke, Elise, Slater, Jayne, King, Dominic, Brooks, Johanne, Baker, Pearl, Beadle, Hannah, Cruz, Carina, Potter, Debbie, Collum, Joe, Masters, Farzana, Kumar, Aashish, Coetzee, Samantha, Peiu, Mihaela, Icke, Becky, Williams, Jill, Raj, Meena, Gaynor, Edward, Chadokufa, Sibongile, Huggett, Bonita, Meghari, Hamza, El-Khouly, Sara, Kiparissi, Fevronia, Girshab, Waffa, Russell-Walker, Lynda, Jackson, Christopher, Sidler, Sara, Claridge, Andrew, Fowler, Emily, McCafferty, Laura, Haxton, Lesley, Irving, Peter, Christodoulides, Karolina, Clifford, Angela, Dawson, Patrick, Honap, Sailish, Lim, Samuel, Luber, Raphael, Mahiouz, Karina, Meade, Susanna, Raymode, Parizade, Reynolds, Rebecca, Stanton, Anna, Tripoli, Sherill, Hare, Naomi, Odukwe, Sopuluchukwu, Balachandran, Senthuran, North, Emma, North, Jessica, Browne, Bria, Cordle, Jessica, Jameson, Ella, Siaw, Yih Harn, Manzano, Lane, Segal, Jonathan, Al-Bakir, Ibrahim, Khakoo, Imran, Portukhay, Sofiya, Thoua, Nora, Davidson, Katherine, Miah, Jagrul, Canclini, Lisa, Hall, Alex, Furreed, Hassina, Mitchell-Inwang, Christine, Hayes, Melony, Myers, Sally, Talbot, Alison, Turnbull, Jack, Whitehead, Emma, Stamp, Katie, Pattinson, Alison, Mathew, Verghese, Sherris, Leanne, Wilcox, Julie, Ramachandran, Sankaranarayanan, Robertson, Hayley, Harvey, Angela, Hicks, Lucy, Byrne, Tara-Marie, Cabreros, Leilani, Downing-Wood, Hannah, Hunter, Sophie, Saifuddin, Mohammad Aamir, Prabhudev, Hemanth, Balarajah, Sharmili, Krucznski, Jan, Driva, Kalliopi, D'Mello, Andrea, Shah, Parith, Castro-Seoane, Rocio, Ibraheim, Hajir, Constable, Laura E, Lo, Jonathan W, Torkizadeh, Melissa, Hermangild, Sherine K, Sutherland, Helen, Wilhelmsen, Elva, Mackintosh, Katherine, Verma, Ajay M, Sebastian, Juliemol, Peerally, Mohammad Farhad, Guerdette, Anne-marie, Coburn, Susan, Novem lam, Ching Yee, Durrant, Donna, Schaefer, Belinda, Serna, Solange, Shahzad, Muhammad, Kent, Alexandra, Choong, Lee Meng, Pantaloni, Benedetta, Ravdas, Pantelis, Vadamalayan, Babu, Foley, Stephen, Arnold, Becky, Heeley, Cheryl, Lovegrove, Wayne, Sowton, Donna, Allsop, Lynne, Gregory, Heidi, Gill, Mandy, Holmes, Megan, Balan, Valeria, Smith, Susan, Turner, Sarah, Smith, Philip J, Steel, Alan, Bretland, Giovanna, King, Sarah, Lofthouse, Martina, Rigby, Lindsey, Subramanian, Sreedhar, Tyrer, David, Martin, Kate, Probert, Christopher, Kamperidis, Nikolaos, Adedoyin, Temi, Baden, Manisha, Brown, Jeannette, Chacko, Feba, Young, Lisa, Cicchetti, Michela, Saifuddin, Mohammad, Yesupatham, Priya, Gowda, Rohit, Williams, Maureen, Kemp, Karen, Akhand, Rima, Gray, Glaxy, John, Anu, John, Maya, Mohammed, Tasnim, Sathe, Diamond, Jones, Natasha, Soren, Jennifer, Sprakes, Michael, Burton, Julie, Kane, Patricia, Lupton, Stephanie, Bartholomew, Jacqueline, Denis, Elizabeth, Daniels, Alison, MacFaul, George, Scaletta, Diane, Siamia, Loria, Williams, Felicity, Green, Chloe, Ver, Zeljka, Lamb, Chris, Doona, Mary, Hogg, Ashleigh, Jeffrey, Lesley, King, Andrew, Speight, R Alexander, Doyle, Jennifer, Owen, Ruth, Haworth, Jenny, Patterson, Linda, Varnaulasingam, Vithusa, Mowat, Craig, Rice, Debbie, MacFarlane, Susan, MacLeod, Anne, Mohammed, Samera, Murray, Shona, Elliott, Anne, Anne Morris, Mary, Coke, Louise, Hindle, Grace, Kolokouri, Eirini, Wright, Catherine, Lee, Claire, Ward, Nicola, Dann, Adele, Lockett, Melanie, Cranfield, Charlotte, Jennings, Louise, Srivastava, Ankur, Ward, Lana, Jeynes, Nouf, Ranga, Poonam, Rajasekhar, Praveen, Gallagher, Lisa, Ward, Jill, Basnett, Rae, Murphy, Judy, Parking, Lauren, Lawson, Emma, Short, Stacey, Devadason, David, Moran, Gordon, Khan, Neelam, Tarr, Lauren, Olivia, Charmaine, Warbarton, Samantha, Kelly, Sian, Limdi, Jimmy, Goulden, Kay, Javed, Asad, McKenzie, Lauren, Melville, Julie, Liu, Eleanor, Sabine, Joseph, Jacob, Patricia, McSorland, Denise, Schofield, Nick, Cornwall, Lisa, Quirke, James, Crook, Emma, Turner, Anne, Bhandari, Pradeep, Baker-Moffatt, Michelle, Dash, Joanne, Le Poidevin, Alison, Downe, Hayley, Bombeo, Lucille, Blackman, Helen, Smith, Rebecca, Wiles, Alan, Bloxham, Hannah, Dias, Jose, Nadar, Evelyn, Curgenven, Hollie, Gilham, Ellie, Macdonald, Jonathan, Finan, Shona, McMeeken, Faye, Mahmood, Misbah, Shields, Stephanie, Seenan, John Paul, DeSilva, Des, Malkakorpi, Susanna, Carson, Rachel, Lawrence, Holly, Boateng, Ofori, Kpodo, Felix, Whiteoak, Simon, Edger-Earley, Kelli, Vamplew, Luke, Samways, Joanna, Roffe, Sue, Ingram, Sarah, James, Joel, Botfield, Sharon, Hammonds, Fiona, James, Clare, Berry, Zoe, Aspinall, Gemma, Hawkins, Sarah, Parkinson, Marian, Gardner-Thorpe, Helen, Marriott, Suzie, Redstone, Clare, Windak, Halina, Adam, Ana-Marie, Mabb, Hannah, Stevenson, Emma, Record, Jessica, Murray, Charles, Diaba, Cynthia, Joseph, Fexy, Pakou, Glykeria, Gleeson, Yvonne, Nunag, Annalyn, Berrill, James, Stroud, Natalie, Pothecary, Carla, Roche, Lisa, Turner, Keri, Deering, Lisa, Israel, Lynda, Baker, Evelyn, Nash, Maxine, Fagbemi, Andrew, Jennings, Felicia, Mayor, Imelda, Wilson, Jill, Wheeler, Alice, Phillips, Nicola, Gordon, John, Levell, Emma, Zagalo, Silvia, Hoad, Ina, Anil, Bindu, Russell, Richard, Henderson, Paul, Millar, Margaret, Alexakis, Christopher, Michalak, Natalia, Marriott, Cheryl, Stone, Sarah, Pristopan, Veronika, Saunders, John, Burton, Helen, Cambridge, Vanessa, Clark, Tonia, Ekblad, Charlotte, Hierons, Sarah, Katebe, Joyce, Saunsbury, Emma, Perry, Rachel, Brookes, Matthew, Davies, Kathryn, Green, Marie, Plumbe, Ann, Ormerod, Clare, Christensen, Helen, Howlett, Hannah, Keen, Anne, Ogor, Jonathan, Greenhaigh, Marie, Knowles, Karen, Yin, Shanzi, Poulaka, Maria, Anthony, Alpha, Newitt, Emily, Trim, Fiona, Casey, Ruth, Seymour, Katherine, Reed, Catherine, Joy, Lijo, Fogden, Edward, Russell, Kalisha, Hussain, Samia, Phillips, Anne, Abdulla, Muaad, Butterworth, Jeff, Adams, Colene, Carnahan, Mandy, Buckingham, Elizabeth, Childs, Danielle, Magness, Alison, Stickley, Jo, Motherwell, Nichola, Tonks, Louise, Gibson, Hannah, Wistance, Kate, Thomas, Caradog, Brinkworth, Elaine, Connor, Lynda, Cook, Amanda, Rees, Tabitha, Harford, Rachel, Farley, Sean, Jones, Marie, Wesley, Emma, Moss, Alison, Lucas, Jacob, Lorimer, Claire, Oleary, Maria, Dixon, Maxine, Goodchild, Fiona, Twenlow, Rebecca, Pawley, Corinne, Ramadas, Arvind, Tregonning, Julie, Okeke, Olaku, Jackson, Wendy, Koumoutsos, Ioannis, George, Viji, Kunhunny, Swapna, Laverick, Sophie, Anderson, Isla, Smith, Sophie, Joyce, Joan, Janarthan, Sarala, Patel, Kamal, Ali, Mariam, Mhandu, Hilda, Rana, Aleem, Spears, Katherine, Teixeira, Joana, Mencias, Mark, Seaward, Abigail, Sousa, Jessica, Said, Nooria, Soomaroo, Mark, Raspa, Valentina, Tacouri, Asha, Reps, Nicholas, Martin, Rebecca, Samakomva, Tinashe, Selinger, Christian, Carbonell, Jenelyn, Onovira, Felicia, Quartey, Doris, L'Anson, Alice, Ashworth, Andrew, Bailey, Jessica, Dunn, Angie, Bespaloi, Gjuzel, Rasalan, Harold, Mahmood, Zahid, Campbell, Racheal, Marsh, Liane, Coughlan, Tricia, Jafar, Wisam, Marrs, Janet, McPheat, Christopher, Rahman, Monira, Davies, Sarah, Habibi, Ruth, Jessup-Dunton, Ellen, Joefield, Teishel, Layug, Reina, Patel, Vinod, Vere, Joanne, Turner, Victoria, Kilroy, Susan, Coulding, Martina, Clark, Martyn, McCormick, Jacqueline, Nisar, Attiya, Walker, Gareth, Atkins, Stacey, Growdon, Jasmine, George, Becky, McNeill, Charlotte, Reed, Bryony, Foulds, Angela, Marshall, Catherine, Allison, Michele, Dillon, Briony, Cooney, Rachel, Bennett, Lillie, Bowlas, Louise, Shariff, Sharafaath, Fraser, Aileen, Punnette, Dwayne, Lambert, Rebecca, Bishop-Hurman, Charlotte, Undrell, Elizabeth, Belfield, Katherine, Din, Said, Addleton, Catherine, Appleby, Marie, Brown, Johanna, Holding, Kathleen, Fraser, Catherine, Birkenshaw, Janice, Williams, Jodie, Maulion, Kamille, Lane, Meg, Kravale, Arita, Smith, Claud, Hooper, Patricia, deCaestecker, John, Watchorn, Olivia, Clarke, Ellie, Hayward, Chris, Inniss, Susan, Pritchard, Lucy, Rudge, Karen, Carney, Amanda, Griffee, Sarah, Andreyev, Jervoise, Babu, Sathish, Hayhurst, Caroline, Lockwood, Carol, Osborne, Lynn, Roper, Amanda, Warner, Karen, Hindle, Julia, Lawrence, Tara, Netherton, Kimberley, Watt, Caroline, Szymiczek, Kinga, Mehta, Shameer, Bell, James, Blad, William, Whitley, Lisa, Jastrub, Roman, Durai, Dhamaraj, Baker, Mark, John Sivamurugan, Elizabeth, Evans, Mim, Cummings, Fraser, Harris, Clare, Jones, Amy, Krauze, Liga, Rahmany, Sohail, Earl, Michelle, Vowles, Jenny, Torokwa, Audrey, Petrova, Mirela, Procter, Andrew, Stanley, Jo, Silvamoniz, Claudia, Bettey, Marion, Wahid, Amar, Morrison, Zoe, Thomas-Turner, Rhian, Yendle, Louise, Muller, Jennifer, Mitchell, Marcus, Kirkwood, John, Barnes, Anna, Chaudhary, Rakesh, Claridge, Melanie, Ellis, Chiara, Kemp, Cheryl, Tobi, Ogwa, Milton, Jentus, Johnston, Emma, Oblak, Metod, Winpenny, Carmen, Svensson, Marie-Louise, Godden, Jo, Ashhar, Marium, Alexander, Debbie, Covil, Kate, Derikx, Lauranne, Siakavellas, Sryros, Baxter, Helen, Robertson, Scott, Smith, Linda, Poulose, Beena, Colemam, Anne, Balint, Margareta, Rhys-Jones, Gareth, Watters, Helen, Begg, Susan, Grosalcalde, Beatriz, Coyle, Judy, Johns, Kerrie, Hughes, Rachel, Phipps, Janet, Taylor, Abigail, MacPhee, Catherine, Brooks, Suzanne, John, Jolene, Edwards, Michelle, Smith, Katie, Howard, Linda, Wood, Dianne, Muddu, Ajay, Barman, Laura, Mallinson, Janine, Neale, Tania, Ionita, Diana, Elliot, Kerry, Turnball, Alison, Thomas, Iola, Thomas, Alice, Andrews, Kelly, Sutton, Jonathon, Mulvaney Jones, Caroline, Roberts, Julia, Bishop, Jeannie, Liu, Zhigang, Le, Kaixing, Zhou, Xin, Alexander, James L, Lin, Simeng, Bewshea, Claire, Chanchlani, Neil, Nice, Rachel, McDonald, Timothy J, Lamb, Christopher A, Sebastian, Shaji, Kok, Klaartje, Lees, Charlie W, Hart, Ailsa L, Pollok, Richard C, Boyton, Rosemary J, Altmann, Daniel M, Pollock, Katrina M, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, and Powell, Nick

Published
2023
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6. Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study

Author

Abdale, Shukri, Abbasi, Abdullah, Abusrewil, Anwar, Aghimien, Precious, Ahmed, Saeed, Ali, Akram, Ali, Amjad, Alkhoury, Jad, Allen, Patrick, Al-Rifaie, Ammar, Appleby, Richard, Arasaradnam, Ramesh, Arebi, Naila, Arms-Williams, Bradley, Ashraf, Muteeb, Au, Andrea, Avades, Tamar, Ayubi, Homira, Azhar, Saleha, Baillie, Samantha, Balarajah, Sharmili, Bancil, Aaron, Basit, Abdul, Bayati, Murad, Bell, Andrew, Berry, Alexander, Bhat, Shivaram, Bhattacharyya, Joya, Bishop, Sophia, Blackmore, Laura, Bond, Ashley, Borg-Bartolo, Simon, Botwright, Emma, Bouri, Sonia, Boyle, Stephen, Bradley, Neil, Brailsford, Fiona, Britton, Deborah, Brown, Caitlin, Butcher, Rhys, Butterworth, Jeffrey, Campbell, Rachel, Campbell, Roisin, Campbell, Iona, Carr, Ruth, Carter, Josiah, Cartlidge, Peter, Chandy, Rajiv, Chatten, Kelly, Chaudhary, Rakesh, Chee, Desmond, Cheesbrough, Jonathan, Churchhouse, Antonia, Chughtai, Sara, Clough, Jennie, Cole, Alexander, Cook, Johannah, Cooney, Rachel, Cotton, Sarah, Coulter, Archibald, Critchlow, Tamsin, Cuison, Frederic, Curran, Chris, Darie, Ana-Maria, Dart, Robin, Davwar, Pantong, Dawa, Kasamu Kabiru, Dhar, Anjan, Din, Shahida, Diong, Kok Leong, Disney, Benjamin, Dooks, Emma, Downey, Louise, D'Souza, Anita, Dyall, Lovesh, El Masri, Ali El Rida, Elias, Mary, Evans, Holli, Felwick, Richard, Finegan, Michael, Flanagan, Paul, Fofaria, Rishi, Fong, Steven Chung Ming, Fox, Richard, Fraser, Aileen, Frunza, Christian, Ghodeif, Alhassan, Ghosh, Nivedita, Gilroy, Leah, Good, Larissa, Gordon, John, Grasso, Nicola, Guéroult, Aurelién M, Gulliver, James, Guthrie, Sarah, Gwiggner, Markus, Hanna, Mina, Harlow, Christopher, Harrison, Wendy, Hart, Ailsa, Hawthorne, Barney, Henshaw, Julie, Herdman-Grant, Rosaleen, Hooper, Patricia, Howard, Willow, Hussain, Nasir, Hutton, Thomas, Htun, Aye Mya, Irving, Peter, Jagdish, Reema, Javed, Anum, Javed, Asima, Jayasooriya, Nishani, Johnson, Matthew, Johnston, Emma, Jones, Gareth-Rhys, Kanagasundaram, Cynthia, Karagkouni, Fotein, Kemp, Karen, Kemp, Cheryl, Khalil, Hesham, Khan, Najeebullah, Khasawneh, Mais, Khurshid, Bilal, King, Andrew, Kirkham, Beverley, Kirkham, Fiona, Kokwaro, Flora, Korani, Mohamed, Koumoutsos, Ioannis, Kumar, Aditi, Kuzhiyanjal, Anish John Kuriakose, Lakeland, Martyn, Laverick, Sophie, Lees, Charlie, Levell, Emma, Levison, Scott, Lim, Samuel, Lim, Yuen-Hui, Limdi, Jimmy, Lindsay, James Oliver, Lisle, Jessica, Lobo, Alan, Luber, Raphael, Lucaciu, Laura, Lyne, Holly, MacDonald, Jonathan, Mahalingam, Aarani, Mahgoub, Sara, Malakar, Ridhima, Marley, Fenella, Mason, Joy, Mazhar, Zia, McCaughan, Hannah, Naughton, Tracy, McCulloch, Adam, McIlwaine, Stuart, Meah, Nirmol, Mebarek, Leila, Mendall, Mike, Meiarasu, Radharetnas, Mir, Nasir, Mills, Tilly, Milton, Jentus, Moffat, Victoria, Moran, Gordon W, Morris, Liam, Morrison, Gary, Morrison, Graham, Mulligan, Robert, Murray, Charles, Murray, Jennifer, Musharaf, Mutwakil, Myers, Sally, Naeck-Boolauky, Pineshwari, Naranjo, Andres, Navaratnam, Janardhan, Naylor, Deanna, Nixon, Emma, Nixon, Kirsty, Nooredinvand, Hesam Ahmadi, Nosegbe, Uche, Olabintan, Olaolu, Ong Ming San, Elaine, Okpeh, Comfort, Owen, Hayley, Owen, Ruth, Palmer-Jones, Christopher, Peddada, Kalyan, Peerally, Mohammad, Perkins, Rebecca, Phillips, Frank, Pohl, Keith, Pollok, Richard, Powell, Nick, Qayyum, Farah, Qurashi, Maria, Quraishi, Mohammed Nabil, Ratcliffe, Elizabeth, Radford, Shellie, Rahmany, Sohail, Ramadan, Hanin, Ramadas, Arvind, Reddington, Anne, Riley, Tom, Rimmer, Peter, Ritchie, Susan, Roscoe, Jacqueline, Rosiou, Konstantina, Rowland, Siobhan, Sabine, Joseph, Saifuddin, Aamir, Samaan, Mark, Sarkar, Priya, Sarwar, Shahzad, Sasegbon, Ayodele, Saunders, Jayne, Sebepos-Rogers, Gregory, Seenan, John Paul, Selinger, Christian, Serna, Solange, Sethi, Sonika, Shale, Matthew, Shenderey, Richard, Shenoy, Achuth, Sherifat, Yousuf, Sheth, Roosey, Siakavellas, Spyros, Sikafi, Rafid, Singh, Amar, Singh, Salil, Singh, Updesh, Sivaji, Ganesh, Smith, Philip, Speight, R Alexander, Spence, Andy, Stansfield, Catherine, Steed, Helen, Suseeharan, Kishaani, Tabuso, Maria, Taucius, Donatas, Taylor, Joanne, Thakor, Amit, Tham, Tony, Townsend, Gill, Townsend, Tristan, Troth, Thomas, Tunney, Ruth, Turner, Kelly, Umar, Nosheen, Vakeeswarasarma, Vithushan, Verma, Ajay M, Wallace, Hazel, Wallis, Katharina, Walton, Hannah, Wang, Bo, Warner, Eleanor, Watson, Callum, Watson, Eleanor, Wen, Susie, Widlak, Monika, Williams, Maureen, Woods, Amy, Younge, Lisa, Zafar, Mansoor, Sebastian, Shaji, Walker, Gareth J, Kennedy, Nicholas A, Conley, Thomas E, Patel, Kamal V, Subramanian, Sreedhar, Kent, Alexandra J, Segal, Jonathan P, Brookes, Matthew J, Bhala, Neeraj, Gonzalez, Haidee A, Hicks, Lucy C, Mehta, Shameer J, and Lamb, Christopher A

Published
2021
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7. SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement

Author

Norton, Christine, Din, Shahida, Glatter, Jackie, Kammermeier, Jochen, Ramdeen, Madhoor, Quraishi, Nabil, Sagar, Peter, Radford, Shellie, Speight, R. Alexander, Steed, Helen, Mcfarlane, Michael, Hawthorne, A. Barney, Alexander, James L, Moran, Gordon W, Gaya, Daniel R, Raine, Tim, Hart, Ailsa, Kennedy, Nicholas A, Lindsay, James O, MacDonald, Jonathan, Segal, Jonathan P, Sebastian, Shaji, Selinger, Christian P, Parkes, Miles, Smith, Philip J, Dhar, Anjan, Subramanian, Sreedhar, Arasaradnam, Ramesh, Lamb, Christopher A, Ahmad, Tariq, Lees, Charlie W, Dobson, Liz, Wakeman, Ruth, Iqbal, Tariq H, Arnott, Ian, and Powell, Nick

Published
2021
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13. Establishing Key Performance Indicators for Inflammatory Bowel Disease in the United Kingdom

Author

Quraishi, Mohammed, Dobson, Elizabeth, Ainley, Rachel, Din, Shahida, Wakeman, Ruth, Cummings, Fraser, Sebastian, Shaji, Bloom, Stuart, K. Limdi, Jimmy, Dhar, Anjan, Speight, R Alexander, Bodger, Keith, Kennedy, Nicholas A, Lamb, Christopher, Arnott, Ian, and Selinger, Christian

Subjects
Key performance indicators, Quality improvement, Inflammatory bowel disease
Abstract

Background and aimsHealthcare quality improvement is the systematic process to continuously improve the quality of care and outcomes for patients. The landmark Inflammatory Bowel Disease UK National Audits provided a means to measure the variation in care, highlighting the need to define the standards of excellence in IBD care. Through a consensus approach, we aimed to establish key performance indicators (KPIs), providing reliable benchmarks for IBD care delivery in UK.MethodsKPIs that measure critical aspects of a patient journey within an IBD service were identified though stakeholder meetings. A two stage Delphi consensus was then conducted. The first involved a multidisciplinary team of IBD clinicians and patients to refine definitions and methodology. The second stage assessed feasibility and utility of the proposed QI process by surveying gastroenterology services across UK. ResultsFirstly, the four proposed KPIs were refined and included time from primary care referral todiagnosis in secondary care, time to treatment recommendation following a diagnosis, appropriate use of steroids and advanced therapies pre-screening and assessment. Secondly, the Delphi consensus reported >85% agreement on the feasibility of local adoption of the QI process and >75%agreement on the utility of benchmarking of the KPIs.Conclusions:Through a structured approach we propose quantifiable KPIs for benchmarking to improve and reduce the individual variation in IBD care across the UK.

Published
2023

14. Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab after three doses of COVID-19 vaccine (CLARITY IBD): an analysis of a prospective multicentre cohort study

Author

Liu, Zhigang, primary, Le, Kaixing, additional, Zhou, Xin, additional, Alexander, James L, additional, Lin, Simeng, additional, Bewshea, Claire, additional, Chanchlani, Neil, additional, Nice, Rachel, additional, McDonald, Timothy J, additional, Lamb, Christopher A, additional, Sebastian, Shaji, additional, Kok, Klaartje, additional, Lees, Charlie W, additional, Hart, Ailsa L, additional, Pollok, Richard C, additional, Boyton, Rosemary J, additional, Altmann, Daniel M, additional, Pollock, Katrina M, additional, Goodhand, James R, additional, Kennedy, Nicholas A, additional, Ahmad, Tariq, additional, Powell, Nick, additional, Islam, Madiha, additional, Croft, Nick, additional, Cipriano, Bessie, additional, Francia, Caroline, additional, Khalid, Nosheen, additional, Kingston, Ashley, additional, Lee, Irish, additional, Lehmann, Anouk, additional, Naik, Kinnari, additional, Samuels, Kevin, additional, Plaatjies, Nicolene, additional, Khatun, Hafiza, additional, Bokth, Farjana, additional, Pabriaga, Elise, additional, Saich, Rebecca, additional, Cousins, Hayley, additional, Fraser, Wendy, additional, Thomas, Rachel, additional, Brown, Matthew, additional, White, Benjamin, additional, Kirkineziadis, Nikolaos, additional, Tilley, Bernadette, additional, Porter, Pennie, additional, Bryant, Rachel, additional, Robaczewska, Natalia, additional, Muhammed, Rafeeq, additional, Bi, Rehana, additional, Cotter, Catherine, additional, Grove, Jayne, additional, Hong, Kate, additional, Howman, Ruth, additional, Mitchell, Monica, additional, Clayton, Sophie, additional, Rogers, Louise, additional, Sultan, Sugrah, additional, Rooney, Melanie, additional, Cottrill, Charlotte, additional, Singh, Salil, additional, Dawe, Chris, additional, Hull, Robert, additional, Silva, Natalie, additional, Chadwick, Julie, additional, Robertson, Laura, additional, Manning, Jonathan, additional, Finlayson, Lauren, additional, Roebuck, Allison, additional, Dawson, Joy, additional, Sonwalkar, Sunil, additional, Chambers, Naomi, additional, Robinson, Matthew, additional, Haigh, Andrew, additional, Matapure, Lear, additional, Raine, Tim, additional, George, Varun, additional, Kapizioni, Christina, additional, Strongili, Konstantina, additional, Thompson, Tina, additional, Ahmed, Mohamed, additional, Kontos, Christos, additional, Dawson, Claire, additional, Bourges, Christophe, additional, Barbutti, Isabella, additional, Gozzard, Megan E, additional, Hendy, Philip, additional, Bull, Rhian, additional, Costa, Patricia, additional, Davey, Lisa, additional, Hannington, Hayley, additional, Nundlall, Kribashnie, additional, Martins, Catarina, additional, Avanzi, Laura, additional, Carungcong, Jaime, additional, Barr, Sabrina, additional, Appleby, Richard, additional, Johnson, Emma, additional, Shakweh, Eathar, additional, Phillis, Kath, additional, Gascoyne, Rachel, additional, Crowder, Amanda, additional, Whileman, Amanda, additional, London, Ian, additional, Grounds, Jenny, additional, Martin, Emmeline, additional, Pajak, Susie, additional, Price, Jude, additional, Cawley, Kathryn, additional, Powell, Sandra, additional, Kearsley, Nichola, additional, Dhar, Anjan, additional, Brown, Ellen, additional, Cowton, Amanda, additional, Stamp, Kimberley, additional, Warner, Ben, additional, Stuart, Carmel, additional, Lacey, Louise, additional, de Silva, Shanika, additional, Allcock, Clare, additional, Harvey, Philip, additional, Jones, Lesley, additional, Cooke, Elise, additional, Slater, Jayne, additional, King, Dominic, additional, Brooks, Johanne, additional, Baker, Pearl, additional, Beadle, Hannah, additional, Cruz, Carina, additional, Potter, Debbie, additional, Collum, Joe, additional, Masters, Farzana, additional, Kumar, Aashish, additional, Coetzee, Samantha, additional, Peiu, Mihaela, additional, Icke, Becky, additional, Williams, Jill, additional, Raj, Meena, additional, Gaynor, Edward, additional, Chadokufa, Sibongile, additional, Huggett, Bonita, additional, Meghari, Hamza, additional, El-Khouly, Sara, additional, Kiparissi, Fevronia, additional, Girshab, Waffa, additional, Russell-Walker, Lynda, additional, Jackson, Christopher, additional, Sidler, Sara, additional, Claridge, Andrew, additional, Fowler, Emily, additional, McCafferty, Laura, additional, Haxton, Lesley, additional, Irving, Peter, additional, Christodoulides, Karolina, additional, Clifford, Angela, additional, Dawson, Patrick, additional, Honap, Sailish, additional, Lim, Samuel, additional, Luber, Raphael, additional, Mahiouz, Karina, additional, Meade, Susanna, additional, Raymode, Parizade, additional, Reynolds, Rebecca, additional, Stanton, Anna, additional, Tripoli, Sherill, additional, Hare, Naomi, additional, Odukwe, Sopuluchukwu, additional, Balachandran, Senthuran, additional, North, Emma, additional, North, Jessica, additional, Browne, Bria, additional, Cordle, Jessica, additional, Jameson, Ella, additional, Siaw, Yih Harn, additional, Manzano, Lane, additional, Segal, Jonathan, additional, Al-Bakir, Ibrahim, additional, Khakoo, Imran, additional, Portukhay, Sofiya, additional, Thoua, Nora, additional, Davidson, Katherine, additional, Miah, Jagrul, additional, Canclini, Lisa, additional, Hall, Alex, additional, Furreed, Hassina, additional, Mitchell-Inwang, Christine, additional, Hayes, Melony, additional, Myers, Sally, additional, Talbot, Alison, additional, Turnbull, Jack, additional, Whitehead, Emma, additional, Stamp, Katie, additional, Pattinson, Alison, additional, Mathew, Verghese, additional, Sherris, Leanne, additional, Wilcox, Julie, additional, Ramachandran, Sankaranarayanan, additional, Robertson, Hayley, additional, Harvey, Angela, additional, Hicks, Lucy, additional, Byrne, Tara-Marie, additional, Cabreros, Leilani, additional, Downing-Wood, Hannah, additional, Hunter, Sophie, additional, Saifuddin, Mohammad Aamir, additional, Prabhudev, Hemanth, additional, Balarajah, Sharmili, additional, Krucznski, Jan, additional, Driva, Kalliopi, additional, D'Mello, Andrea, additional, Shah, Parith, additional, Castro-Seoane, Rocio, additional, Ibraheim, Hajir, additional, Constable, Laura E, additional, Lo, Jonathan W, additional, Torkizadeh, Melissa, additional, Hermangild, Sherine K, additional, Sutherland, Helen, additional, Wilhelmsen, Elva, additional, Mackintosh, Katherine, additional, Verma, Ajay M, additional, Sebastian, Juliemol, additional, Peerally, Mohammad Farhad, additional, Guerdette, Anne-marie, additional, Coburn, Susan, additional, Novem lam, Ching Yee, additional, Durrant, Donna, additional, Schaefer, Belinda, additional, Serna, Solange, additional, Shahzad, Muhammad, additional, Kent, Alexandra, additional, Choong, Lee Meng, additional, Pantaloni, Benedetta, additional, Ravdas, Pantelis, additional, Vadamalayan, Babu, additional, Foley, Stephen, additional, Arnold, Becky, additional, Heeley, Cheryl, additional, Lovegrove, Wayne, additional, Sowton, Donna, additional, Allsop, Lynne, additional, Gregory, Heidi, additional, Gill, Mandy, additional, Holmes, Megan, additional, Balan, Valeria, additional, Smith, Susan, additional, Turner, Sarah, additional, Smith, Philip J, additional, Steel, Alan, additional, Bretland, Giovanna, additional, King, Sarah, additional, Lofthouse, Martina, additional, Rigby, Lindsey, additional, Subramanian, Sreedhar, additional, Tyrer, David, additional, Martin, Kate, additional, Probert, Christopher, additional, Kamperidis, Nikolaos, additional, Adedoyin, Temi, additional, Baden, Manisha, additional, Brown, Jeannette, additional, Chacko, Feba, additional, Young, Lisa, additional, Cicchetti, Michela, additional, Saifuddin, Mohammad, additional, Yesupatham, Priya, additional, Gowda, Rohit, additional, Williams, Maureen, additional, Kemp, Karen, additional, Akhand, Rima, additional, Gray, Glaxy, additional, John, Anu, additional, John, Maya, additional, Mohammed, Tasnim, additional, Sathe, Diamond, additional, Jones, Natasha, additional, Soren, Jennifer, additional, Sprakes, Michael, additional, Burton, Julie, additional, Kane, Patricia, additional, Lupton, Stephanie, additional, Bartholomew, Jacqueline, additional, Denis, Elizabeth, additional, Daniels, Alison, additional, MacFaul, George, additional, Scaletta, Diane, additional, Siamia, Loria, additional, Williams, Felicity, additional, Green, Chloe, additional, Ver, Zeljka, additional, Lamb, Chris, additional, Doona, Mary, additional, Hogg, Ashleigh, additional, Jeffrey, Lesley, additional, King, Andrew, additional, Speight, R Alexander, additional, Doyle, Jennifer, additional, Owen, Ruth, additional, Haworth, Jenny, additional, Patterson, Linda, additional, Varnaulasingam, Vithusa, additional, Mowat, Craig, additional, Rice, Debbie, additional, MacFarlane, Susan, additional, MacLeod, Anne, additional, Mohammed, Samera, additional, Murray, Shona, additional, Elliott, Anne, additional, Anne Morris, Mary, additional, Coke, Louise, additional, Hindle, Grace, additional, Kolokouri, Eirini, additional, Wright, Catherine, additional, Lee, Claire, additional, Ward, Nicola, additional, Dann, Adele, additional, Lockett, Melanie, additional, Cranfield, Charlotte, additional, Jennings, Louise, additional, Srivastava, Ankur, additional, Ward, Lana, additional, Jeynes, Nouf, additional, Ranga, Poonam, additional, Rajasekhar, Praveen, additional, Gallagher, Lisa, additional, Ward, Jill, additional, Basnett, Rae, additional, Murphy, Judy, additional, Parking, Lauren, additional, Lawson, Emma, additional, Short, Stacey, additional, Devadason, David, additional, Moran, Gordon, additional, Khan, Neelam, additional, Tarr, Lauren, additional, Olivia, Charmaine, additional, Warbarton, Samantha, additional, Kelly, Sian, additional, Limdi, Jimmy, additional, Goulden, Kay, additional, Javed, Asad, additional, McKenzie, Lauren, additional, Melville, Julie, additional, Liu, Eleanor, additional, Sabine, Joseph, additional, Jacob, Patricia, additional, McSorland, Denise, additional, Schofield, Nick, additional, Cornwall, Lisa, additional, Quirke, James, additional, Crook, Emma, additional, Turner, Anne, additional, Bhandari, Pradeep, additional, Baker-Moffatt, Michelle, additional, Dash, Joanne, additional, Le Poidevin, Alison, additional, Downe, Hayley, additional, Bombeo, Lucille, additional, Blackman, Helen, additional, Smith, Rebecca, additional, Wiles, Alan, additional, Bloxham, Hannah, additional, Dias, Jose, additional, Nadar, Evelyn, additional, Curgenven, Hollie, additional, Gilham, Ellie, additional, Macdonald, Jonathan, additional, Finan, Shona, additional, McMeeken, Faye, additional, Mahmood, Misbah, additional, Shields, Stephanie, additional, Seenan, John Paul, additional, DeSilva, Des, additional, Malkakorpi, Susanna, additional, Carson, Rachel, additional, Lawrence, Holly, additional, Boateng, Ofori, additional, Kpodo, Felix, additional, Whiteoak, Simon, additional, Edger-Earley, Kelli, additional, Vamplew, Luke, additional, Samways, Joanna, additional, Roffe, Sue, additional, Ingram, Sarah, additional, James, Joel, additional, Botfield, Sharon, additional, Hammonds, Fiona, additional, James, Clare, additional, Berry, Zoe, additional, Aspinall, Gemma, additional, Hawkins, Sarah, additional, Parkinson, Marian, additional, Gardner-Thorpe, Helen, additional, Marriott, Suzie, additional, Redstone, Clare, additional, Windak, Halina, additional, Adam, Ana-Marie, additional, Mabb, Hannah, additional, Stevenson, Emma, additional, Record, Jessica, additional, Murray, Charles, additional, Diaba, Cynthia, additional, Joseph, Fexy, additional, Pakou, Glykeria, additional, Gleeson, Yvonne, additional, Nunag, Annalyn, additional, Berrill, James, additional, Stroud, Natalie, additional, Pothecary, Carla, additional, Roche, Lisa, additional, Turner, Keri, additional, Deering, Lisa, additional, Israel, Lynda, additional, Baker, Evelyn, additional, Nash, Maxine, additional, Fagbemi, Andrew, additional, Jennings, Felicia, additional, Mayor, Imelda, additional, Wilson, Jill, additional, Wheeler, Alice, additional, Phillips, Nicola, additional, Gordon, John, additional, Levell, Emma, additional, Zagalo, Silvia, additional, Hoad, Ina, additional, Anil, Bindu, additional, Russell, Richard, additional, Henderson, Paul, additional, Millar, Margaret, additional, Alexakis, Christopher, additional, Michalak, Natalia, additional, Marriott, Cheryl, additional, Stone, Sarah, additional, Pristopan, Veronika, additional, Saunders, John, additional, Burton, Helen, additional, Cambridge, Vanessa, additional, Clark, Tonia, additional, Ekblad, Charlotte, additional, Hierons, Sarah, additional, Katebe, Joyce, additional, Saunsbury, Emma, additional, Perry, Rachel, additional, Brookes, Matthew, additional, Davies, Kathryn, additional, Green, Marie, additional, Plumbe, Ann, additional, Ormerod, Clare, additional, Christensen, Helen, additional, Howlett, Hannah, additional, Keen, Anne, additional, Ogor, Jonathan, additional, Greenhaigh, Marie, additional, Knowles, Karen, additional, Yin, Shanzi, additional, Poulaka, Maria, additional, Anthony, Alpha, additional, Newitt, Emily, additional, Trim, Fiona, additional, Casey, Ruth, additional, Seymour, Katherine, additional, Reed, Catherine, additional, Joy, Lijo, additional, Fogden, Edward, additional, Russell, Kalisha, additional, Hussain, Samia, additional, Phillips, Anne, additional, Abdulla, Muaad, additional, Butterworth, Jeff, additional, Adams, Colene, additional, Carnahan, Mandy, additional, Buckingham, Elizabeth, additional, Childs, Danielle, additional, Magness, Alison, additional, Stickley, Jo, additional, Motherwell, Nichola, additional, Tonks, Louise, additional, Gibson, Hannah, additional, Wistance, Kate, additional, Thomas, Caradog, additional, Brinkworth, Elaine, additional, Connor, Lynda, additional, Cook, Amanda, additional, Rees, Tabitha, additional, Harford, Rachel, additional, Farley, Sean, additional, Jones, Marie, additional, Wesley, Emma, additional, Moss, Alison, additional, Lucas, Jacob, additional, Lorimer, Claire, additional, Oleary, Maria, additional, Dixon, Maxine, additional, Goodchild, Fiona, additional, Twenlow, Rebecca, additional, Pawley, Corinne, additional, Ramadas, Arvind, additional, Tregonning, Julie, additional, Okeke, Olaku, additional, Jackson, Wendy, additional, Koumoutsos, Ioannis, additional, George, Viji, additional, Kunhunny, Swapna, additional, Laverick, Sophie, additional, Anderson, Isla, additional, Smith, Sophie, additional, Joyce, Joan, additional, Janarthan, Sarala, additional, Patel, Kamal, additional, Ali, Mariam, additional, Mhandu, Hilda, additional, Rana, Aleem, additional, Spears, Katherine, additional, Teixeira, Joana, additional, Mencias, Mark, additional, Seaward, Abigail, additional, Sousa, Jessica, additional, Said, Nooria, additional, Soomaroo, Mark, additional, Raspa, Valentina, additional, Tacouri, Asha, additional, Reps, Nicholas, additional, Martin, Rebecca, additional, Samakomva, Tinashe, additional, Selinger, Christian, additional, Carbonell, Jenelyn, additional, Onovira, Felicia, additional, Quartey, Doris, additional, L'Anson, Alice, additional, Ashworth, Andrew, additional, Bailey, Jessica, additional, Dunn, Angie, additional, Bespaloi, Gjuzel, additional, Rasalan, Harold, additional, Mahmood, Zahid, additional, Campbell, Racheal, additional, Marsh, Liane, additional, Coughlan, Tricia, additional, Jafar, Wisam, additional, Marrs, Janet, additional, McPheat, Christopher, additional, Rahman, Monira, additional, Davies, Sarah, additional, Habibi, Ruth, additional, Jessup-Dunton, Ellen, additional, Joefield, Teishel, additional, Layug, Reina, additional, Patel, Vinod, additional, Vere, Joanne, additional, Turner, Victoria, additional, Kilroy, Susan, additional, Coulding, Martina, additional, Clark, Martyn, additional, McCormick, Jacqueline, additional, Nisar, Attiya, additional, Walker, Gareth, additional, Atkins, Stacey, additional, Growdon, Jasmine, additional, George, Becky, additional, McNeill, Charlotte, additional, Reed, Bryony, additional, Foulds, Angela, additional, Marshall, Catherine, additional, Allison, Michele, additional, Dillon, Briony, additional, Cooney, Rachel, additional, Bennett, Lillie, additional, Bowlas, Louise, additional, Shariff, Sharafaath, additional, Fraser, Aileen, additional, Punnette, Dwayne, additional, Lambert, Rebecca, additional, Bishop-Hurman, Charlotte, additional, Undrell, Elizabeth, additional, Belfield, Katherine, additional, Din, Said, additional, Addleton, Catherine, additional, Appleby, Marie, additional, Brown, Johanna, additional, Holding, Kathleen, additional, Fraser, Catherine, additional, Birkenshaw, Janice, additional, Williams, Jodie, additional, Maulion, Kamille, additional, Lane, Meg, additional, Kravale, Arita, additional, Smith, Claud, additional, Hooper, Patricia, additional, deCaestecker, John, additional, Watchorn, Olivia, additional, Clarke, Ellie, additional, Hayward, Chris, additional, Inniss, Susan, additional, Pritchard, Lucy, additional, Rudge, Karen, additional, Carney, Amanda, additional, Griffee, Sarah, additional, Andreyev, Jervoise, additional, Babu, Sathish, additional, Hayhurst, Caroline, additional, Lockwood, Carol, additional, Osborne, Lynn, additional, Roper, Amanda, additional, Warner, Karen, additional, Hindle, Julia, additional, Lawrence, Tara, additional, Netherton, Kimberley, additional, Watt, Caroline, additional, Szymiczek, Kinga, additional, Mehta, Shameer, additional, Bell, James, additional, Blad, William, additional, Whitley, Lisa, additional, Jastrub, Roman, additional, Durai, Dhamaraj, additional, Baker, Mark, additional, John Sivamurugan, Elizabeth, additional, Evans, Mim, additional, Cummings, Fraser, additional, Harris, Clare, additional, Jones, Amy, additional, Krauze, Liga, additional, Rahmany, Sohail, additional, Earl, Michelle, additional, Vowles, Jenny, additional, Torokwa, Audrey, additional, Petrova, Mirela, additional, Procter, Andrew, additional, Stanley, Jo, additional, Silvamoniz, Claudia, additional, Bettey, Marion, additional, Wahid, Amar, additional, Morrison, Zoe, additional, Thomas-Turner, Rhian, additional, Yendle, Louise, additional, Muller, Jennifer, additional, Mitchell, Marcus, additional, Kirkwood, John, additional, Barnes, Anna, additional, Chaudhary, Rakesh, additional, Claridge, Melanie, additional, Ellis, Chiara, additional, Kemp, Cheryl, additional, Tobi, Ogwa, additional, Milton, Jentus, additional, Johnston, Emma, additional, Oblak, Metod, additional, Winpenny, Carmen, additional, Svensson, Marie-Louise, additional, Godden, Jo, additional, Ashhar, Marium, additional, Alexander, Debbie, additional, Covil, Kate, additional, Derikx, Lauranne, additional, Siakavellas, Sryros, additional, Baxter, Helen, additional, Robertson, Scott, additional, Smith, Linda, additional, Poulose, Beena, additional, Colemam, Anne, additional, Balint, Margareta, additional, Rhys-Jones, Gareth, additional, Watters, Helen, additional, Begg, Susan, additional, Grosalcalde, Beatriz, additional, Coyle, Judy, additional, Johns, Kerrie, additional, Hughes, Rachel, additional, Phipps, Janet, additional, Taylor, Abigail, additional, MacPhee, Catherine, additional, Brooks, Suzanne, additional, John, Jolene, additional, Edwards, Michelle, additional, Smith, Katie, additional, Howard, Linda, additional, Wood, Dianne, additional, Muddu, Ajay, additional, Barman, Laura, additional, Mallinson, Janine, additional, Neale, Tania, additional, Ionita, Diana, additional, Elliot, Kerry, additional, Turnball, Alison, additional, Thomas, Iola, additional, Thomas, Alice, additional, Andrews, Kelly, additional, Sutton, Jonathon, additional, Mulvaney Jones, Caroline, additional, Roberts, Julia, additional, and Bishop, Jeannie, additional

Published
2023
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26. OC-0524 Evidence supporting anal and rectal cancer MR-only radiotherapy planning clinical implementation

Author

Bird, D., primary, Nix, M., additional, Tyyger, M., additional, Beasley, M., additional, McCallum, H., additional, Teo, M., additional, Casanova, N., additional, Cooper, R., additional, Gilbert, A., additional, Buckley, D., additional, Sebag-Montefiore, D., additional, Henry, A., additional, Speight, R., additional, and Al-Qaisieh, B., additional

Published
2021
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28. Multicentre, deep learning, synthetic-CT generation for ano-rectal MR-only radiotherapy treatment planning

Author

Bird, D, Nix, MG, McCallum, H, Teo, M, Gilbert, A, Casanova, N, Cooper, R, Buckley, DL, Sebag-Montefiore, D, Speight, R, Al-Qaisieh, B, and Henry, AM

Abstract

Background and purpose Comprehensive dosimetric analysis is required prior to the clinical implementation of pelvic MR-only sites, other than prostate, due to the limited number of site specific synthetic-CT (sCT) dosimetric assessments in the literature. This study aims to provide a comprehensive assessment of a deep learning-based, conditional generative adversarial network (cGAN) model for a large ano-rectal cancer cohort. The following challenges were investigated; T2-SPACE MR sequences, patient data from multiple centres and the impact of sex and cancer site on sCT quality. Method RT treatment position CT and T2-SPACE MR scans, from two centres, were collected for 90 ano-rectal patients. A cGAN model trained using a focal loss function, was trained and tested on 46 and 44 CT-MR ano-rectal datasets, paired using deformable registration, respectively. VMAT plans were created on CT and recalculated on sCT. Dose differences and gamma indices assessed sCT dosimetric accuracy. A linear mixed effect (LME) model assessed the impact of centre, sex and cancer site. Results A mean PTV D95% dose difference of 0.1% (range: −0.5% to 0.7%) was found between CT and sCT. All gamma index (1%/1 mm threshold) measurements were >99.0%. The LME model found the impact of modality, cancer site, sex and centre was clinically insignificant (effect ranges: −0.4% and 0.3%). The mean dose difference for all OAR constraints was 0.1%. Conclusion Focal loss cGAN models using T2-SPACE MR sequences from multiple centres can produce generalisable, dosimetrically accurate sCTs for ano-rectal cancers.

Published
2021

31. P002 Methodological development of single-cell phenotyping and spatial analysis of intestinal leukocyte, stromal and epithelial cell populations in inflammatory bowel disease formalin fixed paraffin embedded tissue by Hyperion imaging mass cytometry

Author

Lamb, C A, primary, Doyle, J, additional, Hulme, G, additional, Cooke, K, additional, Au-Yeung, A, additional, Ojeda-Garcia, J, additional, Fuller, A, additional, McDonald, D, additional, Mansfield, J C, additional, Kirby, J A, additional, McBride, J, additional, Speight, R A, additional, O’Gorman, W, additional, and Filby, A, additional

Published
2021
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32. Assessment, endoscopy, and treatment in patients with acute severe ulcerative colitis during the COVID-19 pandemic (PROTECT-ASUC): a multicentre, observational, case-control study

Author

Sebastian, Shaji, primary, Walker, Gareth J, additional, Kennedy, Nicholas A, additional, Conley, Thomas E, additional, Patel, Kamal V, additional, Subramanian, Sreedhar, additional, Kent, Alexandra J, additional, Segal, Jonathan P, additional, Brookes, Matthew J, additional, Bhala, Neeraj, additional, Gonzalez, Haidee A, additional, Hicks, Lucy C, additional, Mehta, Shameer J, additional, Lamb, Christopher A, additional, Abdale, Shukri, additional, Abbasi, Abdullah, additional, Abusrewil, Anwar, additional, Aghimien, Precious, additional, Ahmed, Saeed, additional, Ali, Akram, additional, Ali, Amjad, additional, Alkhoury, Jad, additional, Allen, Patrick, additional, Al-Rifaie, Ammar, additional, Appleby, Richard, additional, Arasaradnam, Ramesh, additional, Arebi, Naila, additional, Arms-Williams, Bradley, additional, Ashraf, Muteeb, additional, Au, Andrea, additional, Avades, Tamar, additional, Ayubi, Homira, additional, Azhar, Saleha, additional, Baillie, Samantha, additional, Balarajah, Sharmili, additional, Bancil, Aaron, additional, Basit, Abdul, additional, Bayati, Murad, additional, Bell, Andrew, additional, Berry, Alexander, additional, Bhat, Shivaram, additional, Bhattacharyya, Joya, additional, Bishop, Sophia, additional, Blackmore, Laura, additional, Bond, Ashley, additional, Borg-Bartolo, Simon, additional, Botwright, Emma, additional, Bouri, Sonia, additional, Boyle, Stephen, additional, Bradley, Neil, additional, Brailsford, Fiona, additional, Britton, Deborah, additional, Brown, Caitlin, additional, Butcher, Rhys, additional, Butterworth, Jeffrey, additional, Campbell, Rachel, additional, Campbell, Roisin, additional, Campbell, Iona, additional, Carr, Ruth, additional, Carter, Josiah, additional, Cartlidge, Peter, additional, Chandy, Rajiv, additional, Chatten, Kelly, additional, Chaudhary, Rakesh, additional, Chee, Desmond, additional, Cheesbrough, Jonathan, additional, Churchhouse, Antonia, additional, Chughtai, Sara, additional, Clough, Jennie, additional, Cole, Alexander, additional, Cook, Johannah, additional, Cooney, Rachel, additional, Cotton, Sarah, additional, Coulter, Archibald, additional, Critchlow, Tamsin, additional, Cuison, Frederic, additional, Curran, Chris, additional, Darie, Ana-Maria, additional, Dart, Robin, additional, Davwar, Pantong, additional, Dawa, Kasamu Kabiru, additional, Dhar, Anjan, additional, Din, Shahida, additional, Diong, Kok Leong, additional, Disney, Benjamin, additional, Dooks, Emma, additional, Downey, Louise, additional, D'Souza, Anita, additional, Dyall, Lovesh, additional, El Masri, Ali El Rida, additional, Elias, Mary, additional, Evans, Holli, additional, Felwick, Richard, additional, Finegan, Michael, additional, Flanagan, Paul, additional, Fofaria, Rishi, additional, Fong, Steven Chung Ming, additional, Fox, Richard, additional, Fraser, Aileen, additional, Frunza, Christian, additional, Ghodeif, Alhassan, additional, Ghosh, Nivedita, additional, Gilroy, Leah, additional, Good, Larissa, additional, Gordon, John, additional, Grasso, Nicola, additional, Guéroult, Aurelién M, additional, Gulliver, James, additional, Guthrie, Sarah, additional, Gwiggner, Markus, additional, Hanna, Mina, additional, Harlow, Christopher, additional, Harrison, Wendy, additional, Hart, Ailsa, additional, Hawthorne, Barney, additional, Henshaw, Julie, additional, Herdman-Grant, Rosaleen, additional, Hooper, Patricia, additional, Howard, Willow, additional, Hussain, Nasir, additional, Hutton, Thomas, additional, Htun, Aye Mya, additional, Irving, Peter, additional, Jagdish, Reema, additional, Javed, Anum, additional, Javed, Asima, additional, Jayasooriya, Nishani, additional, Johnson, Matthew, additional, Johnston, Emma, additional, Jones, Gareth-Rhys, additional, Kanagasundaram, Cynthia, additional, Karagkouni, Fotein, additional, Kemp, Karen, additional, Kemp, Cheryl, additional, Khalil, Hesham, additional, Khan, Najeebullah, additional, Khasawneh, Mais, additional, Khurshid, Bilal, additional, King, Andrew, additional, Kirkham, Beverley, additional, Kirkham, Fiona, additional, Kokwaro, Flora, additional, Korani, Mohamed, additional, Koumoutsos, Ioannis, additional, Kumar, Aditi, additional, Kuzhiyanjal, Anish John Kuriakose, additional, Lakeland, Martyn, additional, Laverick, Sophie, additional, Lees, Charlie, additional, Levell, Emma, additional, Levison, Scott, additional, Lim, Samuel, additional, Lim, Yuen-Hui, additional, Limdi, Jimmy, additional, Lindsay, James Oliver, additional, Lisle, Jessica, additional, Lobo, Alan, additional, Luber, Raphael, additional, Lucaciu, Laura, additional, Lyne, Holly, additional, MacDonald, Jonathan, additional, Mahalingam, Aarani, additional, Mahgoub, Sara, additional, Malakar, Ridhima, additional, Marley, Fenella, additional, Mason, Joy, additional, Mazhar, Zia, additional, McCaughan, Hannah, additional, Naughton, Tracy, additional, McCulloch, Adam, additional, McIlwaine, Stuart, additional, Meah, Nirmol, additional, Mebarek, Leila, additional, Mendall, Mike, additional, Meiarasu, Radharetnas, additional, Mir, Nasir, additional, Mills, Tilly, additional, Milton, Jentus, additional, Moffat, Victoria, additional, Moran, Gordon W, additional, Morris, Liam, additional, Morrison, Gary, additional, Morrison, Graham, additional, Mulligan, Robert, additional, Murray, Charles, additional, Murray, Jennifer, additional, Musharaf, Mutwakil, additional, Myers, Sally, additional, Naeck-Boolauky, Pineshwari, additional, Naranjo, Andres, additional, Navaratnam, Janardhan, additional, Naylor, Deanna, additional, Nixon, Emma, additional, Nixon, Kirsty, additional, Nooredinvand, Hesam Ahmadi, additional, Nosegbe, Uche, additional, Olabintan, Olaolu, additional, Ong Ming San, Elaine, additional, Okpeh, Comfort, additional, Owen, Hayley, additional, Owen, Ruth, additional, Palmer-Jones, Christopher, additional, Peddada, Kalyan, additional, Peerally, Mohammad, additional, Perkins, Rebecca, additional, Phillips, Frank, additional, Pohl, Keith, additional, Pollok, Richard, additional, Powell, Nick, additional, Qayyum, Farah, additional, Qurashi, Maria, additional, Quraishi, Mohammed Nabil, additional, Ratcliffe, Elizabeth, additional, Radford, Shellie, additional, Rahmany, Sohail, additional, Ramadan, Hanin, additional, Ramadas, Arvind, additional, Reddington, Anne, additional, Riley, Tom, additional, Rimmer, Peter, additional, Ritchie, Susan, additional, Roscoe, Jacqueline, additional, Rosiou, Konstantina, additional, Rowland, Siobhan, additional, Sabine, Joseph, additional, Saifuddin, Aamir, additional, Samaan, Mark, additional, Sarkar, Priya, additional, Sarwar, Shahzad, additional, Sasegbon, Ayodele, additional, Saunders, Jayne, additional, Sebepos-Rogers, Gregory, additional, Seenan, John Paul, additional, Selinger, Christian, additional, Serna, Solange, additional, Sethi, Sonika, additional, Shale, Matthew, additional, Shenderey, Richard, additional, Shenoy, Achuth, additional, Sherifat, Yousuf, additional, Sheth, Roosey, additional, Siakavellas, Spyros, additional, Sikafi, Rafid, additional, Singh, Amar, additional, Singh, Salil, additional, Singh, Updesh, additional, Sivaji, Ganesh, additional, Smith, Philip, additional, Speight, R Alexander, additional, Spence, Andy, additional, Stansfield, Catherine, additional, Steed, Helen, additional, Suseeharan, Kishaani, additional, Tabuso, Maria, additional, Taucius, Donatas, additional, Taylor, Joanne, additional, Thakor, Amit, additional, Tham, Tony, additional, Townsend, Gill, additional, Townsend, Tristan, additional, Troth, Thomas, additional, Tunney, Ruth, additional, Turner, Kelly, additional, Umar, Nosheen, additional, Vakeeswarasarma, Vithushan, additional, Verma, Ajay M, additional, Wallace, Hazel, additional, Wallis, Katharina, additional, Walton, Hannah, additional, Wang, Bo, additional, Warner, Eleanor, additional, Watson, Callum, additional, Watson, Eleanor, additional, Wen, Susie, additional, Widlak, Monika, additional, Williams, Maureen, additional, Woods, Amy, additional, Younge, Lisa, additional, and Zafar, Mansoor, additional

Published
2021
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34. The Solar Orbiter SPICE instrument

Author

Anderson, M., Appourchaux, T., Auchère, F., Aznar Cuadrado, R., Barbay, J., Baudin, F., Beardsley, S., Bocchialini, K., Borgo, B., Bruzzi, D., Buchlin, Eric, Burton, G., Büchel, V., Caldwell, M., Caminade, S., Carlsson, M., Curdt, W., Davenne, J., Davila, J., DeForest, C., Del Zanna, G., Drummond, D., Dubau, J., Dumesnil, C., Dunn, G., Eccleston, P., Fludra, A., Fredvik, T., Gabriel, A., Giunta, A., GOTTWALD, A., Griffin, D., Grundy, T., Guest, S., Gyo, M., Haberreiter, M., Hansteen, V., Harrison, R., Hassler, D., Haugan, S., Howe, C., Janvier, M., Klein, R., Koller, S., Kucera, T., Kouliche, D., Marsch, E., Marshall, A., Marshall, G., Matthews, S., McQuirk, C., Meining, S., Mercier, C., Morris, N., Morse, T., Munro, G., Parenti, S., Pastor-Santos, C., Peter, H., Pfiffner, D., Phelan, P., Philippon, A., Richards, A., Rogers, K., Sawyer, C., Schlatter, P., Schmutz, W., Schühle, U., Shaughnessy, B., Sidher, S., Solanki, S., Speight, R., Spescha, M., Szwec, N., Tamiatto, C., Teriaca, L., Thompson, W., Tosh, I., Tustain, S., Vial, J.-C., Walls, B., Waltham, N., Wimmer-Schweingruber, R., Woodward, S., Young, P., De Groof, A., Pacros, A., Williams, D., Müller, D., Institut d'astrophysique spatiale (IAS), and Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract

International audience; Aims. The Spectral Imaging of the Coronal Environment (SPICE) instrument is a high-resolution imaging spectrometer operating at extreme ultraviolet (EUV) wavelengths. In this paper, we present the concept, design, and pre-launch performance of this facility instrument on the ESA/NASA Solar Orbiter mission. Methods. The goal of this paper is to give prospective users a better understanding of the possible types of observations, the data acquisition, and the sources that contribute to the instrument's signal. Results. The paper discusses the science objectives, with a focus on the SPICE-specific aspects, before presenting the instrument's design, including optical, mechanical, thermal, and electronics aspects. This is followed by a characterisation and calibration of the instrument's performance. The paper concludes with descriptions of the operations concept and data processing. Conclusions. The performance measurements of the various instrument parameters meet the requirements derived from the mission's science objectives. The SPICE instrument is ready to perform measurements that will provide vital contributions to the scientific success of the Solar Orbiter mission.

Published
2020

36. SARS-CoV-2 vaccination for patients with inflammatory bowel disease: a British Society of Gastroenterology Inflammatory Bowel Disease section and IBD Clinical Research Group position statement

Author

Alexander, James L, primary, Moran, Gordon W, additional, Gaya, Daniel R, additional, Raine, Tim, additional, Hart, Ailsa, additional, Kennedy, Nicholas A, additional, Lindsay, James O, additional, MacDonald, Jonathan, additional, Segal, Jonathan P, additional, Sebastian, Shaji, additional, Selinger, Christian P, additional, Parkes, Miles, additional, Smith, Philip J, additional, Dhar, Anjan, additional, Subramanian, Sreedhar, additional, Arasaradnam, Ramesh, additional, Lamb, Christopher A, additional, Ahmad, Tariq, additional, Lees, Charlie W, additional, Dobson, Liz, additional, Wakeman, Ruth, additional, Iqbal, Tariq H, additional, Arnott, Ian, additional, Powell, Nick, additional, Norton, Christine, additional, Din, Shahida, additional, Glatter, Jackie, additional, Kammermeier, Jochen, additional, Ramdeen, Madhoor, additional, Quraishi, Nabil, additional, Sagar, Peter, additional, Radford, Shellie, additional, Speight, R. Alexander, additional, Steed, Helen, additional, Mcfarlane, Michael, additional, and Hawthorne, A. Barney, additional

Published
2021
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38. Gastrointestinal mucosal damage in patients with COVID-19 undergoing endoscopy: an international multicentre study

Author

Vanella, Giuseppe, primary, Capurso, Gabriele, additional, Burti, Cesare, additional, Fanti, Lorella, additional, Ricciardiello, Luigi, additional, Souza Lino, Andre, additional, Boskoski, Ivo, additional, Bronswijk, Michiel, additional, Tyberg, Amy, additional, Krishna Kumar Nair, Govind, additional, Angeletti, Stefano, additional, Mauro, Aurelio, additional, Zingone, Fabiana, additional, Oppong, Kofi W., additional, de la Iglesia-Garcia, Daniel, additional, Pouillon, Lieven, additional, Papanikolaou, Ioannis S., additional, Fracasso, Pierluigi, additional, Ciceri, Fabio, additional, Rovere-Querini, Patrizia, additional, Tomba, Carolina, additional, Viale, Edi, additional, Eusebi, Leonardo Henry, additional, Riccioni, Maria Elena, additional, van der Merwe, Schalk, additional, Shahid, Haroon, additional, Sarkar, Avik, additional, Yoo, Jin Woo (Gene), additional, Dilaghi, Emanuele, additional, Speight, R. Alexander, additional, Azzolini, Francesco, additional, Buttitta, Francesco, additional, Porcari, Serena, additional, Petrone, Maria Chiara, additional, Iglesias-Garcia, Julio, additional, Savarino, Edoardo V., additional, Di Sabatino, Antonio, additional, Di Giulio, Emilio, additional, Farrell, James J., additional, Kahaleh, Michel, additional, Roelandt, Philip, additional, Costamagna, Guido, additional, Artifon, Everson Luiz de Almeida, additional, Bazzoli, Franco, additional, Testoni, Per Alberto, additional, Greco, Salvatore, additional, and Arcidiacono, Paolo Giorgio, additional

Published
2021
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40. A Systematic Review of the Clinical Implementation of Pelvic Magnetic Resonance Imaging (MR)-Only Planning for External Beam Radiation Therapy

Author

Bird, D, Henry, AM, Sebag-Montefiore, D, Buckley, DL, Al-Qaisieh, B, and Speight, R

Abstract

The use of magnetic resonance imaging (MRI) scans alone for radiotherapy treatment planning (MR-only planning) has been highlighted as one method of improving patient outcomes. Recent technological advances have meant that introducing MR-only planning to the clinic is now becoming a reality, with several specialist radiotherapy clinics treating patients with this technique. As such, substantial efforts are being made to introduce this technique into wide-spread clinical implementation. A systematic review of publications investigating the clinical implementation of pelvic MR-only radiotherapy treatment planning was undertaken following the PRISMA guidelines. The Medline, Embase, Scopus, Science Direct, CINAHL and Web of Science databases were searched (timespan: all years to 2nd January 2019). Twenty six articles met the inclusion criteria. The studies were grouped into the following categories: 1. MR acquisition and synthetic-CT generation verification, 2. MR distortion quantification and phantom development, 3. Clinical validation of patient treatment positioning in an MR-only workflow and 4. MR-only commissioning processes. Key conclusions from this review are: i) MR-only planning has been clinically implemented for prostate cancer treatments; ii) A substantial amount of work remains to translate MR-only planning into wide spread clinical implementation for all pelvic sites; iii) MR scanner distortions are no longer a barrier to MR-only planning; however they must be managed appropriately; iv) MR-only based patient positioning verification shows promise, however limited evidence is reported in the literature and further investigation is required; and v) a number of MR-only commissioning processes have been reported which can aid centres as they undertake local commissioning, however this needs to be formalised in guidance from national bodies.

Published
2019

47. PH-0406: An IPEM international survey of MRI use for external beam RT treatment planning

Author

Speight, R., primary, Tyyger, M., additional, Schmidt, M.A., additional, Liney, G.P., additional, Johnstone, R.I., additional, Eccles, C.L., additional, Dubec, M., additional, George, B., additional, Henry, A., additional, Nyholm, T., additional, Mahmood, F., additional, Korhonen, J., additional, Sims, R., additional, Tijssen, R.H.N., additional, Vanhoutte, F., additional, Busoni, S., additional, Lacornerie, T., additional, and McCallum, H., additional

Published
2020
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