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Medical errors related to antineoplastic drugs are subject to multilple researches, whereas in the Republic of Croatia, that is still a subject of discussion. Insufficient information which would serve as a basis for a conclusion about the extent medical error is present in Croatian hospital system. By supervising prescribed drugs, dosages, solutions, and correct preparation and instructions for accurate application, oncology pharmacists can to a great extent contribute to a safe application of drugs in hospitals, reducing, by doing so, the margin of medication error. Drugs that make part of the chemotherapy protocol of a patient, accompanied or not by biological therapy, get prepared in accordance with instructions from the Summaries of Product Characteristics (SPC). Due to individual differences between patients and the need to adjust these protocols, other referential data from literature are also used. Antineoplastic drugs are prepared in microbiologically validated space by manipulation in aseptic conditions. Sterile state of the prepared drug is of outstanding importance, because the immune system of oncology patients is often compromised due to side effects which are the consequence of the therapy itself. By organizing the entire procedure, from recieving and control of the request for chemotherapy, the pre-preparation procedure, the preparation, visual control of ready preparations, the packaging of chemotherapy and its application at wards, an entire system of multiple controls prior to application is established. In this way, we attempt to reduce the occurence of undesired events which could threaten the health of the patient and increase treatment costs. In everyday work the most used are the world and the national guidelines as well as QUAPOS - Quality Standard for the Oncology Pharmacy Service edited by ESOP ( European Society of Oncology Pharmacy).

Oncology patients are facing numerous psychological consequences (hard disease, mourning for lost functions, anxiety, depression, fear of the future) among which are very often neglected changes in the field of love and sexuality. Because of disease and the treatment (chemotherapy and radiotherapy) there are multiple physical changes which may result by damaging the secondary health (e.g. iatrogenic menopause, hormonal imbalance, atrophy of the vaginal mucosa). Some frequent sexual problems are low sexual desire, problems with libido and dyspareunia. However, beside of the physical changes, there are psychological changes which can affect the sexuality (low self-esteem, changed body image, fear of losing attraction in partner, and depression) which may have as consequences the avoidance of sex, reduced sexual desire and reduced intimacy. Apart from sexuality, there is often loss of intimacy between partners and due to reducing communication their love and closeness can be affected. Considering patients which will never first speak about their sexual and love problems, every expert (doctor, pharmacist) who participate in the treatment of oncology patient should learn skills how to communicate with the patient about love, sex and methods how to keep their sexual health. This consultation should involve education about physiology and psychology of sexuality, using of sexual toys, imagination, stimulation, improving communication between partners, stimulating their conversations, exploring and experimenting in changed conditions and tighten their relationships, love and closeness.