352 results on '"Spadari S"'
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2. Mammalian DNA Polymerase α: A Replication-Competent Holoenzyme Form from Calf Thymus
3. Lack of enantioselectivity of herpes virus thymidine kinase allows safer imaging of gene delivery
4. The Major DNA Polymerase in Cultured Plant Cells: Partial Purification and Correlation with Cell Multiplication
5. DNA Methylation and DNA Structure
6. Alteration of Dna Structure: The Common Result of the Interaction Between DNA and Physical and Chemical Agents
7. On the Molecular Mechanism of Mutagenesis by Carcinogenic Mutagens
8. Inactivation of aphidicolin by plant cells
9. Ribonucleotide reductase potential inhibitors: Design, synthesis and activity of bioisosters of ribofuranosylnucleoside diphosphates
10. Localization of ribosomal RNA genes on human acrocentric chromosomes
11. Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. Synthesis and Biological Evaluation of Novel Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Antiviral Agents
12. Pyrrolobenzoxazepinone (PBO) Derivatives as Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further Structure-Activity Relationship Studies and Identification of More Potent Broad Spectrum HIV-1 RT Inhibitors with Antiviral Activity
13. MAKING AND CORRECTING ERRORS IN DNA SYNTHESIS : IN VITRO STUDIES OF MUTAGENESIS
14. Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy-pyrimidine nucleoside triphosphates: molecular basis for the combination of L-dideoxynucleoside analogs with non-nucleoside inhibitors in anti HIV chemotherapy
15. 2,4-Dioxo-5-hexenoic Acid Derivatives Are Novel Selective Non-Nucleoside Inhibitors of Mammalian Terminal Deoxynucleotidyl Transferases, with Potent Cytotoxic Effect Against Leukemic Cells
16. Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda
17. Diketo hexenoic acid (DKHA) derivatives are novel selective non nucleoside inhibitors of mammalian terminal deoxynucleotidyl transferases, with potent cytotoxic effect against leukemic cells
18. Gln145Met/Leu changes in HIV-1 RT confer resistance to nucleoside and non-nucleoside analogs and impair virus replication
19. Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1
20. The stereoselective targeting of a specific enzyme-substrate complex is the molecular mechanism for the synergic inhibition of HIV-1 reverse transcriptase by (R)-(-)-PPO464: a novel generation of nonnucleoside inhibitors
21. Potentiation of inhibition of wild-type and mutant human immunodeficiency virus type 1 reverse transcriptases by combinations of nonnucleoside inhibitors and d- and L-(beta)-dideoxynucleoside triphosphate analogs
22. The Stereoselective Targeting of a Specific Enzyme-Substrate Complex is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(-)PPO464, a Novel Generation of Non-Nucleoside Inhibitors
23. Replication protein A as a 'fidelity clamp' for DNA polymerase alpha
24. DNA polymerase switching: I. Replication factor C displaces DNA polymerase alpha prior to PCNA loading
25. HERPES-SIMPLEX VIRUS TYPE-1 URACIL-DNA GLYCOSYLASE - CLONING AND CHARACTERIZATION
26. HERPES-SIMPLEX VIRUS TYPE-1 (HSV-1) URACIL-DNA GLYCOSYLASE - FUNCTIONAL EXPRESSION IN ESCHERICHIA-COLI, BIOCHEMICAL-CHARACTERIZATION, AND SELECTIVE-INHIBITION BY 6-(P-N-OCTYLANILINO)URACIL
27. ChemInform Abstract: L-Thymidine is Phosphorylated by Herpes Simplex Virus Type 1 Thymidine Kinase and Inhibits Viral Growth.
28. ChemInform Abstract: Some 6-Aza-5-substituted-2′-deoxyuridines Show Potent and Selective Inhibition of Herpes Simplex Virus Type 1 Thymidine Kinase
29. Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases and
30. Thymidine Phosphorylase: A Two-Face Janus in Anticancer Chemotherapy
31. Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: Synthesis and Biological Evaluation of Novel Quinoxalinylethylpyridylthioureas as Potent Antiviral Agents
32. Synthesis and Molecular Modeling of Novel HSV1 Uracil-DNA Glycosylase Inhibitors
33. Structural Determinants of HIV-1 Reverse Transcriptase Stereoselectivity Towards (β)-L-Deoxy- and Dideoxy-Pyrimidine Nucleoside Triphosphates: Molecular Basis for the Combination of L-Dideoxynucleoside Analogs with Non-nucleoside Inhibitors in Anti HIV Chemotherapy
34. Interaction of β-L-Adenosine-5′-triphosphate (L-ATP) with Human Deoxycytidine Kinase, Human DNA Primase and T4 DNA Ligase: Does the Chance Direct Enzymatic Enantioselectivity?
35. Some 6-Aza-5-substituted-2'-deoxyuridines Show Potent and Selective Inhibition of Herpes Simplex Virus Type 1 Thymidine Kinase
36. 9-(4-hydroxybutyl)-N2-phenylguanine (HBPG), a thymidine kinase inhibitor, suppresses herpes virus reactivation in mice
37. Herpes Simplex Virus Type 1 (HSV-1) Uracil-DNA Glycosylase: Functional Expression in Escherichia coli, Biochemical Characterization, and Selective Inhibition by 6-(p-n-Octylanilino)Uracil
38. Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: Molecular basis for the antiviral activity of unnatural l-β-nucleosides
39. Stereospecificity of human DNA polymerases α,β,γ,§ and ɛ, HIV-reverse transcriptase, HSV- DNA polymerase, calf thymus terminal transferase andEscherichia coliDNA polymerase I in recognizing D- and L-thymidine 5′-triphosphate as substrate
40. Kinetic studies with N2-phenylguanines and with l-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site
41. ChemInform Abstract: Researches on Antiviral Agents. Part 4. Studies on the Chemistry of 6‐ Methyl‐2‐methoxy‐4‐O‐acyloxy and 6‐Methyl‐2,4‐di‐O‐acyloxypyrimidine Derivatives as New Acylation Reagents and Inhibitors of Uracil DNA Glycosylases.
42. DNA replication and chemotherapy
43. Identification, partial purification and inhibition by guanine analogues of a novel enzymic activity which phosphorylates guanosine to GMP in the protozoan parasite Eimeria tenella
44. Myoclonus epilepsy and ragged-red fibers: blood mitochondrial DNA heteroplasmy in affected and asymptomatic members of a family
45. Lack of stereospecificity of suid pseudorabies virus thymidine kinase
46. Herpes simplex virus type 1 uracil-DNA glycosylase: isolation and selective inhibition by novel uracil derivatives
47. Enzymes of DNA Metabolism in a Patient with the Wiedemann-Rautenstrauch Progeroid Syndrome
48. Uracil-DNA glycosylases preferentially excise mispaired uracil
49. Correlation between anthracycline structure and human DNA ligase inhibition
50. Use of ATP, dATP and their α-thio derivatives to study DNA ligase adenylation
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