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922 results on '"Spaan, Jos A"'

1. Impact of core laboratory assessment on treatment decisions and clinical outcomes using combined fractional flow reserve and coronary flow reserve measurements – DEFINE-FLOW core laboratory sub-study

Author

van de Hoef, Tim P., Stegehuis, Valérie E., Madera-Cambero, Maribel I., van Royen, Niels, van der Hoeven, Nina W., de Waard, Guus A., Meuwissen, Martijn, Christiansen, Evald H., Eftekhari, Ashkan, Niccoli, Giampaolo, Lockie, Tim, Matsuo, Hitoshi, Nakayama, Masafumi, Kakuta, Tsunekazu, Tanaka, Nobuhiro, Casadonte, Lorena, Spaan, Jos A.E., Siebes, Maria, Tijssen, Jan G.P., Escaned, Javier, and Piek, Jan J.

Published
2023
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2. The danger of pseudo science in Informetrics

Author

Spaan, Jos AE

Subjects
Computer Science - Digital Libraries, Physics - Popular Physics, Physics - Physics and Society
Abstract

Two papers have been archived to which this letter is complementary: 1) Opthof and Leydesdorff arxiv:1002.2769 2) Van Raan et al. arxiv:1003.2113 Van Raan at all claims that the order of operations (first dividing then adding) does not apply to citation analysis. In my contribution I discuss a few analogues in Physics and Medicine and argue that in no other field of science where quantities have physical or financial meaning, implying that that numbers have a real unit of measure, it would be allowed to ignore the rule of operations. Hence, the claim of CWTS that the order of operations is not relevant brings studies ignoring this rule as done by CWTS in the category 'Pseudo Science'.

Published
2010

4. Impact of core laboratory assessment on treatment decisions and clinical outcomes using combined fractional flow reserve and coronary flow reserve measurements - DEFINE-FLOW core laboratory sub-study

Author

Team Medisch, van de Hoef, Tim P, Stegehuis, Valérie E, Madera-Cambero, Maribel I, van Royen, Niels, van der Hoeven, Nina W, de Waard, Guus A, Meuwissen, Martijn, Christiansen, Evald H, Eftekhari, Ashkan, Niccoli, Giampaolo, Lockie, Tim, Matsuo, Hitoshi, Nakayama, Masafumi, Kakuta, Tsunekazu, Tanaka, Nobuhiro, Casadonte, Lorena, Spaan, Jos A E, Siebes, Maria, Tijssen, Jan G P, Escaned, Javier, Piek, Jan J, Team Medisch, van de Hoef, Tim P, Stegehuis, Valérie E, Madera-Cambero, Maribel I, van Royen, Niels, van der Hoeven, Nina W, de Waard, Guus A, Meuwissen, Martijn, Christiansen, Evald H, Eftekhari, Ashkan, Niccoli, Giampaolo, Lockie, Tim, Matsuo, Hitoshi, Nakayama, Masafumi, Kakuta, Tsunekazu, Tanaka, Nobuhiro, Casadonte, Lorena, Spaan, Jos A E, Siebes, Maria, Tijssen, Jan G P, Escaned, Javier, and Piek, Jan J

Published
2023

9. Modelling Parameter Role on Accuracy of Cardiac Perfusion Quantification

Author

Zarinabad, Niloufar, Chiribiri, Amedeo, Hautvast, Gilion L. T. F., Shuster, Andreas, Sinclair, Matthew, van den Wijngaard, Jeroen P. H. M., Smith, Nicolas, Spaan, Jos A. E., Siebes, Maria, Breeuwer, Marcel, Nagel, Eike, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Ourselin, Sébastien, editor, Rueckert, Daniel, editor, and Smith, Nicolas, editor

Published
2013
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12. Extraction of Coronary Vascular Tree and Myocardial Perfusion Data from Stacks of Cryomicrotome Images

Author

van Horssen, Pepijn, van den Wijngaard, Jeroen P. H. M., Nolte, Froukje, Hoefer, Imo, Haverslag, Rene, Spaan, Jos A. E., Siebes, Maria, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Ayache, Nicholas, editor, Delingette, Hervé, editor, and Sermesant, Maxime, editor

Published
2009
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29. Coronary Circulation Mechanics

Author

Dankelman, Jenny, Stassen, Henk G., Spaan, Jos A. E., Kajiya, Fumihiko, editor, Klassen, Gerald A., editor, Spaan, Jos A. E., editor, and Hoffman, Julien I. E., editor

Published
1990
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43. A quantitative high resolution voxel-wise assessment of myocardial blood flow from contrast-enhanced first-pass magnetic resonance perfusion imaging: microsphere validation in a magnetic resonance compatible free beating explanted pig heart model

Author

Schuster, Andreas, Sinclair, Matthew, Zarinabad, Niloufar, Ishida, Masaki, van den Wijngaard, Jeroen P.H.M., Paul, Matthias, van Horssen, Pepijn, Hussain, Shazia T., Perera, Divaka, Schaeffter, Tobias, Spaan, Jos A.E., Siebes, Maria, Nagel, Eike, and Chiribiri, Amedeo

Published
2015
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45. Myocardial perfusion distribution and coronary arterial pressure and flow signals: clinical relevance in relation to multiscale modeling, a review

Author

Nolte, Froukje, Hyde, Eoin R., Rolandi, Cristina, Lee, Jack, van Horssen, Pepijn, Asrress, Kal, van den Wijngaard, Jeroen P. H. M., Cookson, Andrew N., van de Hoef, Tim, Chabiniok, Radomir, Razavi, Reza, Michler, Christian, Hautvast, Gilion L. T. F., Piek, Jan J., Breeuwer, Marcel, Siebes, Maria, Nagel, Eike, Smith, Nic P., and Spaan, Jos A. E.

Published
2013
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50. Acute attenuation of glycocalyx barrier properties increases coronary blood volume independently of coronary flow reserve

Author

Brands, Judith, Spaan, Jos A.E., Van den Berg, Bernard M., Vink, Hans, and VanTeeffelen, Jurgen W.G.E.

Subjects
Blood flow -- Research, Glycocalyx -- Physiological aspects, Glycocalyx -- Research, Vascular endothelium -- Physiological aspects, Vascular endothelium -- Research, Biological sciences
Abstract

Vascular endothelium is covered with an extensive mesh of glycocalyx constituents, which acts like an effective barrier up to several micrometers thick that shields the luminal surface of the vasculature from direct exposure to flowing blood. Many studies report that various enzymatic and pharmaceutical challenges are able to increase glycocalyx porosity, resulting in farther permeation of plasma macromolecules and greater access of red blood cells into glycocalyx domain. Attenuation of glycocalyx barrier properties therefore potentially increases the amount of blood that effectively occupies available microvascular volume. We tested in the present study whether attenuation of coronary glycocalyx barrier properties actually increases coronary blood volume and whether such changes would be noticeable during measurements of coronary flow reserve using adenosine. In anesthetized goats (n = 6) with cannulated left main coronary artery that were perfused under controlled pressure, coronary blood volume was measured via the indicator-dilution technique using high-molecular-weight (2,000 kDa) dextrans as plasma tracer and labeled red blood cells as red blood cell tracer. Coronary blood volume was determined at baseline and during intracoronary infusion of adenosine causing maximal vasodilation (0.2-0.6 mg'*[kg.sup.-]*[h.sup.-1]) before and after intracoronary hyaluronidase treatment (170,000 units) of the glycocalyx. With an intact glycocalyx, coronary blood volume was 18.9 [+ or -] 1.1 ml/100 g heart tissue at baseline, which increased to 26.3 [+ or -] 2.7 ml/100 g after hyaluronidase treatment of the coronary glycocalyx. Maximal vasodilation by administration of adenosine further increased coronary blood volume to 33.9 [+ or -] 6.8 ml/100 g, a value not different from the maximal coronary blood volume of 33.2 [+ or -] 5.3 ml/100 g obtained by administration of adenosine in the absence of hyaluronidase treatment. Adenosine-induced increases in coronary conductance were not affected by hyaluronidase treatment. We conclude that acute attenuation of glycocalyx barrier properties increases coronary blood volume by ~40%, which is of similar magnitude as additional changes in coronary blood volume during subsequent maximal vasodilation with adenosine. Furthermore, maximal coronary blood volume following administration of adenosine was similar with and without prior hyaluronidase degradation of the glycocalyx, suggesting that adenosine and hyaluronidase potentially increase glycocalyx porosity to a similar extent. Hyaluronidase-mediated changes in coronary blood volume did not affect baseline and adenosine-induced increases in coronary conductance, demonstrating that measurements of coronary flow reserve are insufficient to detect impairment of coronary blood volume recruitment in conditions of damaged glycocalyx. adenosine; blood flow; coronary circulation; indicator-dilution doi: 10.1152/ajpheart.01306.2008.

Published
2010

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